@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1137: (2015-12-21 )
MNTDFSHITDIEGMRFVNEEDALNKLINEIHTRHIDLKDSIMLALSFNALYLANALAQKFGATYDILFLEPILAPLNSKCEIALVSESMDIVMNESLINSFDIALDYVYGEAKRAYEEDILSHIYQYRKGNAIKSLKDKNIFIVDRGIETGFRAGLGVQTCLKKECQDIYILTPILAQNVAQGLESLCDGVISVYRPECFVSVEHHYKELKRLSNEEIEKYLGANNAPNLKKEH
Atome Classification :
(20 SA)
-.........10-.-----------.......20........30.....-.--------..40........-------------50.......-.60-.---..----.----....70.-.......80....---.-...90..-......100.......110......-.120........130.-..-.---------...140.......150---.......160...-.--.-----------------..170.--.--....--.180...-....190.......200---.-----..-------......210.......220...--....230..--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MNTDFSHITDI-E-----------G
M
R
FV
N
E
E
D
A
L
N
K
L
I
N
E
I
H
T
RHID-L--------KD
S
I
M
L
A
L
SF
N
A
-------------
L
Y
L
A
N
A
L
A
Q
-
K
FG-A---
T
Y
----
D
----
I
L
F
L
E
P
I
-
L
APLNSK
C
E
I
A
L
V---S-ES
M
D
I
V
M
-
N
E
S
L
I
N
S
F
D
I
A
L
D
Y
VY
G
E
A
K
R
A
Y
E
E
-
D
I
L
-
S
H
I
Y
Q
Y
RKGNAI-KS-L---------KDK
N
I
F
I
V
DRGIE
T
G
F
---RAGL
G
V
Q
T
C
L
K
KE-C--Q-----------------
D
I
Y
I
L
T
--
P
--
I
L
A
Q
--
N
V
A
Q
G
L
E
-
S
L
C
D
G
V
I
S
VYRP
E
C
F
-----
V
-----
S
V
-------
E
H
H
Y
K
E
L
K
R
L
S
N
E
E
I
E
K
Y
LGAN--NAPNLKKEH--
4
HHSearch
98.08
19%
-123
- C5 -
1WD5
1
?
A:
[1-207]
--------------------------
M
R
F
R
D
R
R
H
A
G
A
L
L
A
E
A
L
A
P
--
L
G
-
L
--------
E
A
P
V
V
L
G
L
P
R
G
G
-------------
V
V
V
A
D
E
V
A
R
-
R
L
G
-
G
---
E
L
----
D
----
V
V
L
V
R
K
V
-
G
A
P
G
N
P
E
F
A
L
G
A
V
---
G
-
E
G
G
E
L
V
L
-
M
P
Y
A
L
R
Y
A
--
D
Q
S
Y
L
E
R
E
A
A
R
Q
R
D
V
--
L
R
-
K
R
A
E
R
Y
R
R
V
R
P
K
-
A
A
-
R
---------
K
G
R
D
V
V
L
V
D
D
G
V
A
T
G
A
---
S
M
E
A
A
L
S
V
V
F
Q
E
G
-
P
--
R
-----------------
R
V
V
V
A
V
--
P
--
V
A
S
P
--
E
A
V
E
R
L
K
-
A
R
A
-
E
V
V
A
L
S
V
P
Q
D
F
-----
A
-----
A
V
-------
G
A
Y
Y
L
D
F
G
E
V
T
D
E
D
V
E
A
I
L
L
E
W
--
A
G
---------
1
PsiBlast_PDB
87.49
19%
-118
- C5 -
1WD5
1
?
A:
[25-203]
-------------------------------------------------------------
P
V
V
L
G
L
P
R
G
G
-------------
V
V
V
A
D
E
V
A
R
-
R
L
G
-
G
---
E
L
----
D
----
V
V
L
V
R
K
V
-
G
A
P
G
N
P
E
F
A
L
G
A
V
---
G
-
E
G
G
E
L
V
L
-
M
P
Y
A
L
R
Y
A
D
Q
S
----
Y
L
E
R
E
A
A
R
Q
R
-
D
V
L
R
K
R
A
E
R
Y
R
R
V
R
P
K
-
A
A
-
R
---------
K
G
R
D
V
V
L
V
D
D
G
V
A
T
G
A
---
S
M
E
A
A
L
S
V
V
F
Q
E
G
-
P
--
R
-----------------
R
V
V
V
A
V
--
P
--
V
A
S
P
--
E
A
V
E
R
L
K
-
A
R
A
E
-
V
V
A
L
S
V
P
Q
D
F
-----
A
-----
A
V
-------
G
A
Y
Y
L
D
F
G
E
V
T
D
E
D
V
E
A
I
L
L
E
W
--
A
G
---------
7
HHSearch
78.00
17%
-128
- C5 -
3OHP
-
?
A:
[9-170]
--------------------------
I
S
E
Q
E
V
A
Q
R
I
R
E
L
G
Q
Q
I
T
E
-
H
Y
Q
-
G
S-------
S
D
L
V
L
V
G
L
L
R
G
S
-------------
F
V
F
M
A
D
L
A
R
-
Q
I
H
-
L
---
T
H
----
Q
----
V
D
F
M
T
A
S
-------------------------------------------------
S
R
D
--
V
-----
R
I
-
L
K
D
-
L
D
-
D
D
-
I
---------
K
G
K
D
V
L
L
V
E
D
I
I
D
T
G
N
---
T
L
N
K
V
K
E
I
L
A
L
R
E
-
P
--
K
-----------------
S
I
R
I
C
T
--
L
--
L
D
K
P
--
T
R
R
-
E
V
--
D
V
E
V
N
W
V
G
F
E
I
P
D
E
F
-----
V
V
G
VG
I
D
Y
-------
A
Q
K
Y
R
H
L
P
Y
I
G
K
V
V
P
L
A
------------------
24
Fugue
70.01
14%
-84
- C5 -
1D9E
2
KDSA_ECOLI
A:
[1-284]
-
M
K
Q
K
V
V
S
I
G
D
I
-
N
V
A
NDLPFVLFG
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
-
L
--------
G
I
P
Y
V
F
K
A
S
F
D
K
ANRSSIHSYRGPG
L
E
E
G
M
K
I
F
Q
-
E
L
K
-
Q
---
T
F
----
G
----
V
----
K
I
-
I
T
D
V
H
E
P
S
Q
A
Q
P
V
---
A
-
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
-
S
P
G
Q
M
G
N
I
V
D
K
F
-
K
E
-
G
---------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
K
V
-
S
--
G
-----------------
N
S
P
V
I
F
--
D
--
V
T
H
A
--
L
Q
R
A
Q
V
A
-
E
L
A
R
A
G
M
A
V
G
L
A
G
L
F
-----
I
-----
E
A
H
PDPEPS
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
--
G
F
E
E
L
D
T
S
K
--
17
HHSearch
68.98
15%
-111
- C5 -
1YFZ
4
?
A:
[38-197]
---------------------------
T
E
E
Q
L
K
A
K
V
K
E
L
G
E
M
I
T
R
-
D
Y
E
-
G
--------
K
D
L
V
L
I
G
V
L
K
G
A
-------------
I
M
F
M
S
G
L
S
R
-
A
I
D
-
L
---
P
L
----
S
----
I
D
F
L
A
V
S
-
S
-----------------
Y
G
S
S
------
T
--------
K
-------
S
--
S
G
I
--
V
------
K
I
I
K
D
-
H
D
-
I
D
-
I
---------
E
G
K
D
V
L
I
V
E
D
I
I
D
S
G
L
---
T
L
A
Y
L
R
E
T
L
L
G
R
K
-
P
--
R
-----------------
S
L
K
I
C
T
--
I
--
L
D
K
P
--
E
R
R
E
-
A
--
D
V
K
V
D
Y
C
G
F
K
I
P
D
K
F
V
V
G
YG
L
-----
D
Y
-------
A
E
K
Y
R
N
L
P
F
I
G
V
L
K
P
E
L
Y
-----------------
15
HHSearch
66.86
15%
-118
- C5 -
2GEB
1
?
A:
[18-177]
---------------------------
T
E
E
Q
L
K
A
K
V
K
E
L
G
E
M
I
T
R
D
-
Y
E
-
G
--------
K
D
L
V
L
I
G
V
L
K
G
A
-------------
I
M
F
M
S
G
L
S
R
-
A
I
D
-
L
---
P
L
----
S
----
I
D
F
L
A
V
S
-
S
-----------------
Y
G
S
S
------------------
T
K
S
-----
S
G
I
--
V
-----
K
I
-
I
K
D
-
H
D
-
I
D
-
I
---------
E
G
K
D
V
L
I
V
E
D
I
I
D
S
G
L
---
T
L
A
Y
L
R
E
T
L
L
G
R
K
-
P
--
R
-----------------
S
L
K
I
C
T
--
I
--
L
D
K
P
--
E
R
R
-
E
A
--
D
V
K
V
D
Y
C
G
F
K
I
P
D
K
F
-----
V
VGYG
I
D
Y
-------
A
E
K
Y
R
N
L
P
F
I
G
V
L
K
P
E
L
Y
-----------------
29
Fugue
66.62
13%
-70
- C5 -
1QB7
3
?
A:
[1-236]
------
P
F
K
E
V
S
-
P
-----------
N
S
F
L
L
D
D
S
H
A
L
S
Q
L
L
K
K
S
Y
R
W
Y
S
P
-
V
--------
F
S
P
R
N
V
P
R
F
A
D
----------------
V
S
S
I
T
E
S
-
P
E
T
-
L
---
K
A
----
I
----
R
D
F
L
V
Q
R
-
Y
R
A
M
S
P
A
P
T
H
I
L
G
---
F
-
D
A
R
G
F
L
F
-
G
P
M
I
A
V
E
L
E
I
P
F
V
L
M
R
K
A
D
K
N
A
-
G
L
-
L
I
R
-
S
E
P
Y
E
K
E
Y
K
E
A
A
-
P
E
-
V
MTIRYGSIG
K
G
S
R
V
V
L
I
D
D
V
L
A
T
G
----
G
T
A
L
S
G
L
Q
L
V
E
A
S
-
D
--
A
-----------------
V
V
V
E
M
V
--
S
--
I
L
S
I
--
P
F
L
K
A
A
E
-
K
I
H
S
T
A
N
S
R
Y
K
D
I
K
F
-----
I
-----
S
L
-------
L
S
-
D
D
A
L
T
E
E
N
C
G
D
S
K
N
Y
T
G
P
R
VL
S
C
G
D
V
L
A
E
H
PH
18
HHSearch
65.86
15%
-112
- C5 -
1VDM
-
?
A:
[8-138]
----------------------------
W
W
Q
V
D
R
A
I
F
A
L
A
E
K
L
R
E
--
Y
-----------
K
P
D
V
I
I
G
V
A
R
G
G
-------------
L
I
P
A
V
R
L
S
H
-
I
L
G
D
I
---
P
L
----
K
----
V
I
D
V
K
F
--------------------
Y
K
G
------------------------
E
--
R
G
E
--
K
-----
P
V
I
T
I
P
-
I
H
-
G
D
-
L
---------
K
D
K
R
V
V
I
V
D
D
V
S
D
T
G
K
---
T
L
E
V
V
I
E
E
V
K
K
L
G
-
A
--
K
-----------------
E
I
K
I
A
C
--
L
--
A
M
K
P
--
W
T
-
S
-----
V
V
P
D
Y
Y
V
F
R
T
E
K
W
I
-----
V
-----
F
P
-------
W
E
E
F
P
V
I
E
K
E
-------------------------
5
HHSearch
64.50
17%
-96
- C5 -
3OZF
4
?
A:
[64-235]
--------------------------
V
P
N
G
V
I
K
N
R
I
E
K
L
A
Y
D
I
K
K
-
V
Y
N
-
N
--------
E
E
F
H
I
L
C
L
L
K
G
S
-------------
R
G
F
F
T
A
L
L
K
-
H
L
S
-
R
---
I
H
----
N
----
Y
S
A
V
E
T
S
--
K
P
L
-
F
G
E
H
Y
V
R
V
K
--
S
-
Y
C
N
D
-----------------------
Q
-
S
T
G
T
--
L
-----
E
I
V
-
S
-
E
D
L
-
S
C
-
L
---------
K
G
K
H
V
L
I
V
E
D
I
I
D
T
G
K
---
T
L
V
K
F
C
E
Y
L
K
K
F
E
-
I
--
K
-----------------
T
V
A
I
A
C
--
L
--
F
I
K
R
--
T
P
L
-
W
N
--
G
F
K
A
D
F
V
G
F
S
I
P
D
H
F
-----
V
V
G
YSL
D
Y
-------
N
E
I
F
R
D
L
D
H
C
C
L
V
N
D
E
G
K
K
K
Y
K
--
A
----------
33
Fugue
63.88
12%
-80
- C5 -
1BD3
3
UPP_TOXGO
A:
[20-243]
Q
E
E
S
I
L
Q
D
I
I
T
R
F
P
-----------
N
V
V
L
M
K
Q
T
A
Q
L
R
A
M
M
T
I
I
R
D
K
E
T
P
-
K
--------
E
E
F
V
F
Y
A
D
R
L
I
R
-------------
L
L
I
E
E
A
L
N
E
L
P
F
Q
-
K
---
K
E
----
V
----
T
T
P
L
D
V
S
-
Y
H
G
V
S
F
Y
S
K
I
C
G
V
---
S
I
V
R
A
G
E
S
M
-
E
S
G
L
R
A
V
C
R
G
V
R
I
G
K
I
L
I
Q
R
D
E
T
T
A
-
E
P
K
-
L
I
Y
E
K
L
P
A
------
D
-
I
---------
R
E
R
W
V
M
L
L
D
P
M
C
A
T
A
G
---
S
V
C
K
A
I
E
V
L
L
R
L
G
-
V
KE
E
-----------------
R
I
I
F
V
N
--
I
--
L
A
A
-----
P
Q
G
I
E
-
R
V
F
K
E
-----
Y
P
K
V
R
-----
M
-----
V
T
-------
A
A
V
D
I
C
L
N
--
S
R
Y
Y
I
V
P
G
I
G
D
F
--
G
D
R
Y
F
G
T
M
---
9
HHSearch
63.80
14%
-107
- C5 -
1FSG
4
HGXR_TOXGO
A:
[52-221]
----------------------------
G
G
L
V
K
D
R
V
E
K
L
A
Y
D
I
H
R
-
T
Y
F
-
G
--------
E
E
L
H
I
I
C
I
L
K
G
S
-------------
R
G
F
F
N
L
L
I
D
-
Y
L
A
-
T
---
I
Q
----
K
------
Y
S
G
R
E
S
S
V
P
P
---
F
F
E
H
Y
V
R
L
K
S
-
Y
Q
N
D
-----------------------
N
-
S
T
G
Q
--
L
-----
T
V
L
-
S
D
-
D
L
-
S
I
-
F
---------
R
D
K
H
V
L
I
V
E
D
I
V
D
T
G
F
---
T
L
T
E
F
G
E
R
L
K
A
V
G
-
P
--
K
-----------------
S
M
R
I
A
T
--
L
--
V
E
K
R
--
T
D
R
-
S
N
--
S
L
K
G
D
F
V
G
F
S
I
E
D
V
W
-----
I
V
G
CCY
D
F
-------
N
E
M
F
R
D
F
D
H
V
A
V
L
S
D
A
A
R
K
K
F
E
--
K
----------
10
HHSearch
62.88
15%
-114
- C5 -
3HVU
2
?
A:
[35-195]
--------------------------
I
S
E
E
Q
I
Q
E
K
V
L
E
L
G
A
I
I
A
E
-
D
Y
K
-
N
--------
T
V
P
L
A
I
G
V
L
K
G
A
-------------
M
P
F
M
A
D
L
L
K
-
R
T
D
-
T
---
Y
L
----
E
----
M
D
F
M
A
V
S
-----------------
S
-
Y
G
H
S
---------------
T
--------
V
S
T
G
E
--
V
-----
K
I
-
L
K
D
-
L
D
-
T
S
-
V
---------
E
G
R
D
I
L
I
V
E
D
I
I
D
S
G
L
---
T
L
S
Y
L
V
D
L
F
K
Y
R
K
-
A
--
K
-----------------
S
V
K
I
V
T
--
L
--
L
D
K
P
--
T
G
R
K
-
V
--
D
L
K
A
D
Y
V
G
F
T
V
P
H
E
F
-----
V
VGYG
L
D
Y
-------
K
E
Q
Y
R
N
L
P
Y
V
G
V
L
K
P
S
V
Y
S
----------------
20
HHSearch
62.28
14%
-139
- C5 -
3DAH
1
?
A:
[149-281]
-------------------------------
N
I
Y
A
T
P
I
L
L
G
D
L
R
K
Q
N
Y
-----------
P
D
L
L
V
V
S
P
D
V
G
G
-------------
V
V
R
A
R
A
L
A
K
-
Q
L
N
-
C
---
D
L
----
A
----
I
-----------------------------------------------------------------------------------------
E
G
R
T
C
V
I
M
D
D
M
V
D
T
A
G
---
T
L
C
K
A
A
Q
V
L
K
E
R
G
-
A
--
K
-----------------
Q
V
F
A
Y
A
TH
P
--
V
L
S
G
--
G
A
A
D
R
I
A
A
S
A
L
D
E
L
V
V
T
D
T
I
P
L
S
-----
A
-----
E
S
-------
L
A
C
P
K
I
R
A
L
S
S
A
G
L
L
A
E
T
F
S
R
I
--
R
R
G
D
S
V
M
S
L
--
22
HHSearch
61.18
14%
-131
* C5 *
3LRT
1
KPRS_THEVO
A:
[140-266]
---------------------------------
H
A
N
D
A
I
V
R
Y
Y
K
N
--
V
-----------
D
V
D
Y
V
V
S
P
D
D
G
G
-------------
L
A
R
V
A
D
I
S
A
-
K
L
G
-
K
---
K
H
----
F
----
F
I
--
E
K
K
-
R
I
D
D
----------------
R
---------------------------
T
V
E
--
M
------
K
V
----
P
N
-
V
D
-
V
---------
N
G
K
K
L
L
I
V
D
D
I
I
S
T
G
G
---
T
I
A
K
S
S
G
L
L
R
E
K
G
-
A
--
S
-----------------
K
I
Y
V
S
A
--
V
HG
L
F
V
N
--
G
S
E
N
K
I
L
-
Q
N
A
D
E
I
H
V
T
D
T
V
E
S
K
-----
F
-----
S
D
-------
I
S
V
Y
Q
E
V
C
N
Y
I
R
D
I
---------------------
21
HHSearch
60.77
14%
-110
- C5 -
1W30
-
PYRR_MYCTU
A:
[17-172]
--------------------------
M
S
A
A
N
V
G
R
T
I
S
R
I
A
H
Q
I
I
E
-
K
T
A
-
L
DDPVGPDA
P
R
V
V
L
L
G
I
P
T
R
G
-------------
V
T
L
A
N
R
L
A
G
-
N
I
T
-
E
---
Y
S
GIH
V
G
----
H
G
A
L
D
I
T
-----------------
L
-
Y
R
D
---------------------------------------
P
L
A
S
T
S
I
P
A
G
G
-
I
---------
D
D
A
L
V
I
L
V
D
D
V
L
Y
S
G
R
---
S
V
R
S
A
L
D
A
L
R
D
V
G
R
P
--
R
-----------------
A
V
Q
L
A
V
--
L
--
V
D
R
G
--
H
-
R
-
E
L
--
P
L
R
A
D
Y
V
G
K
N
V
P
T
S
R
-----
S
-----
E
S
-------
V
H
V
R
L
R
E
H
D
G
R
D
G
V
V
I
S
R
-----------------
23
HHSearch
60.56
11%
-142
- C5 -
3S5J
1
PRPS1_HUMAN
B:
[147-278]
----------------------------------
A
E
P
A
V
L
K
W
I
R
E
-
N
I
S
E
W
--------
R
N
C
T
I
V
S
P
D
A
G
G
-------------
A
K
R
V
T
S
I
A
D
-
R
L
N
-
V
---
D
F
----
A
----
L
I
--
H
K
E
------------------------------------------------------------
D
R
M
---
V
L
V
-
G
D
-
V
---------
K
D
R
V
A
I
L
V
D
D
M
A
D
T
C
G
---
T
I
C
H
A
A
D
K
L
L
S
A
G
-
A
--
T
-----------------
R
V
Y
A
I
L
TH
G
--
I
F
S
G
--
P
A
I
S
R
I
N
N
A
C
F
E
A
V
V
V
T
N
T
I
P
Q
E
-----
D
-----
K
M
-------
K
H
C
S
K
I
Q
V
I
D
I
S
M
I
L
A
E
A
I
R
R
T
--
H
N
G
E
S
V
S
Y
L
--
8
HHSearch
58.69
10%
-121
- C5 -
3ACD
3
?
A:
[15-174]
---------------------------
S
A
E
A
I
K
K
R
V
E
E
L
G
G
E
I
A
R
-
D
Y
Q
-
G
--------
K
T
P
H
L
I
C
V
L
N
G
A
-------------
F
I
F
M
A
D
L
V
R
-
A
I
P
-
L
---
P
L
----
T
----
M
D
F
I
A
I
S
------------------------------------------------------------
E
L
-
L
K
D
-
L
R
-
L
P
-
I
---------
H
G
R
D
V
I
V
V
E
D
I
V
D
T
G
L
---
T
L
S
Y
L
L
D
Y
L
E
A
R
K
-
P
--
A
-----------------
S
V
R
V
A
A
--
L
--
L
S
K
P
--
S
R
R
Q
-
V
--
E
V
P
I
H
Y
L
G
F
E
I
E
D
A
Y
-----
V
Y
G
YGL
D
R
-------
A
Q
F
D
R
N
L
P
F
I
T
S
I
R
P
E
-------------------
14
HHSearch
57.93
9%
-115
- C5 -
3DEZ
3
PYRE_STRMU
A:
[86-236]
----------------------------------
I
E
N
G
F
V
E
T
I
K
E
-
A
F
P
----------
E
V
E
V
I
A
G
T
A
T
A
G
-------------
I
P
H
G
A
I
I
A
D
-
K
M
N
-
L
---
P
L
----
A
----
Y
--
I
R
S
K
-
P
K
---------------------------------------------------------
N
Q
I
-----
E
-
G
R
V
T
---------
K
G
Q
K
M
V
I
I
E
D
L
I
S
T
G
G
---
S
V
L
D
A
V
A
A
A
Q
R
E
G
-
A
--
D
-----------------
V
L
G
V
V
A
--
I
--
F
T
Y
E
L
P
K
A
T
A
N
F
E
-
K
A
S
V
K
L
V
T
L
---
S
N
Y
-----
S
-----
E
L
-------
I
K
V
A
K
V
Q
G
Y
I
D
A
D
G
L
T
L
L
K
K
F
K
--
E
N
Q
E
T
W
Q
D
---
6
HHSearch
57.88
12%
-126
- C5 -
1PZM
1
?
A:
[29-198]
---------------------------
T
Q
E
Q
V
W
A
A
T
A
K
C
A
K
K
I
A
A
-
D
Y
K
-
D
FHLTAD--
N
P
L
Y
L
L
C
V
L
K
G
S
-------------
F
I
F
T
A
D
L
A
R
-
F
L
A
-
D
E
G
V
P
V
----
K
----
V
E
F
I
C
A
S
-------------------------------------------------------------
M
L
-
L
D
-
V
R
-
D
S
-
V
---------
E
N
R
H
I
M
L
V
E
D
I
V
D
S
A
I
---
T
L
Q
Y
L
M
R
F
M
L
A
K
K
-
P
--
A
-----------------
S
L
K
T
V
V
--
L
--
L
D
K
P
--
S
G
R
-
K
V
--
D
V
L
V
D
Y
P
V
I
T
I
P
R
A
F
-----
V
I
G
YG
M
D
F
-------
A
E
S
Y
R
E
L
R
D
I
C
V
L
K
K
E
-------------------
19
HHSearch
57.58
15%
-120
- C5 -
2XBU
2
HPRT_YEAST
A:
[9-161]
--------------------------
I
S
Y
N
N
V
H
Q
L
C
Q
V
S
A
E
R
I
K
--
N
F
-----------
K
P
D
L
I
I
A
I
G
G
G
G
-------------
F
I
P
A
R
I
L
R
T
-
F
L
K
-
E
---
P
G
----
V
P
T
I
R
I
F
A
I
I
L
S
-----------------
L
-
Y
E
-----------------------------
V
K
--
V
S
-
R
T
-
Q
W
I
D
Y
E
Q
C
K
-
L
D
-
L
---------
V
G
K
N
V
L
I
V
D
E
V
D
D
T
R
T
---
T
L
H
Y
A
L
S
E
L
E
K
D
A
-
A
--
E
Q
A
K
A
K
GIDTEKSPEM
K
T
N
F
G
I
F
V
--
L
--
H
D
K
Q
--
K
P
K
K
A
D
L
-
P
A
E
M
L
N
D
K
N
R
Y
F
A
A
K
-----
T
-----
V
P
-------
D
K
W
Y
A
Y
P
W
E
S
T
D
I
V
F
H
T
R
M
A
I
E
--
Q
G
N
D
I
F
I
P
E
--