@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1383: (2015-12-23 )
MDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLALEMSQRLDTYLSATQLGITLSSLALGWVGEPAIAKLLAALFESMDLRENPIFIHSMSVVIAFLSITFLHVVLGEIVPKSLAIAKSEKATLFAARPLHVFWVVFYPVVRLFDVIAHFFLKKMGVNPKEHEGMHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMVCLDEENSYEENIDIVLKSHFTRYPYCKGSKDNIIGMVHIRDLLSRSIFTPKMHDFKQIVRKMIIVPESASISQILIKMKKEQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQEGVNKLEEGVFELEGMLDLESVEEVLHIQFDKECEQVTLGGYVFSLLERMPIEGDTIVSHGYAFEVLSVDGARIKRLKAVKQDQGENEA
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.-......250.......260.......270..--.....280-..--.-....290----.......300.......310.......320-------........330.......340........350...-....360.......370.......380.......390.......400.......410.......420.......430.......440
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDP
S
E
S
I
L
M
L
M
V
A
F
L
L
V
L
L
N
A
F
F
V
L
S
E
F
A
L
V
K
V
R
K
T
R
L
E
E
L
V
K
IGNSN
A
K
L
A
L
E
M
S
Q
R
L
D
T
Y
L
S
A
T
Q
L
G
I
T
L
S
S
L
A
LGWVG
E
P
A
I
A
K
L
L
A
A
L
F
E
SMDLREN
P
I
F
I
H
S
M
S
V
V
I
A
F
L
S
I
T
F
L
H
V
V
L
G
E
IV
P
K
S
L
AIAKSE
K
A
T
L
F
AAR
P
L
H
V
F
W
V
V
F
Y
P
V
V
R
L
F
D
V
I
A
H
F
F
L
K
KMGVN
P
K
E
HEGMH
S
E
E
E
L
K
I
I
V
G
E
S
L
R
E
G
I
I
D
SV
E
G
E
I
I
K
N
AVDFSDT
S
A
K
EIMTPRK
D
M
V
C
LDEENSYEEN-
I
D
I
V
L
KSHFTRYPYCKGSKD
N
I
I
G
M
V
H
I
R
D
L
--
L
S
RSIFTP-
K
M
--
H
-
D
F
K
Q
I
V
R
----
K
M
IIVPESA
S
I
S
Q
I
L
I
K
M
K
K
EQI
H
T
A
L
V
I
--------DEYGGTAG
L
L
T
M
E
D
I
I
E
E
I
M
-
G
EISDEY
D
L
K
Q
E
G
V
-
N
K
L
E
E
G
V
F
E
L
EGML
D
L
E
S
V
E
E
V
L
H
I
QFDKEC
E
Q
V
TL
G
G
Y
V
F
S
L
L
E
RMPIEG
D
T
I
V
SHG
Y
A
F
E
V
L
SVD
G
A
R
I
K
R
L
K
A
V
K
QDQGENEA
2
PsiBlast_PDB
93.11
29%
-83
* C1 *
4HG0
1
CORC_ECOLI
A:
[51-274]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
D
T
R
D
M
L
E
G
V
M
D
I
A
D
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
Q
T
L
D
E
C
-
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
S
E
D
K
D
H
I
E
G
I
L
M
A
K
D
L
--
L
P
F
M
R
S
D
A
-
E
A
--
F
-
S
M
D
K
V
L
R
----
Q
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
--------
D
E
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
V
-
G
E
I
E
D
E
Y
D
E
E
D
D
I
D
F
R
Q
L
S
R
H
T
W
T
V
R
A
L
A
S
I
E
D
F
N
E
A
F
G
T
H
F
S
D
E
-
E
V
D
T
I
G
G
L
V
M
Q
A
F
G
H
L
P
A
R
G
E
T
I
D
I
D
G
Y
Q
F
K
V
A
M
A
D
S
R
R
I
I
Q
V
H
V
K
I
P
-------
41
HHSearch
79.88
32%
-88
- C1 -
3OI8
4
?
A:
[2-156]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
S
A
E
D
V
L
N
L
L
R
Q
A
H
E
Q
E
V
F
D
A
D
T
L
L
R
L
E
K
V
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
N
V
L
K
E
N
D
S
I
E
R
I
-
T
A
Y
V
I
D
T
A
H
S
R
F
P
V
I
G
E
D
K
D
E
V
L
G
I
L
H
A
K
D
L
--
L
K
Y
M
F
N
P
---
E
--
Q
F
H
L
K
S
I
L
R
----
P
A
V
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
--------
D
E
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
---------------------------------------------------------------------------------------------------------
45
HHSearch
79.40
43%
-85
- C1 -
3LV9
1
?
A:
[18-147]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
V
C
I
Y
E
S
D
S
E
E
K
I
-
L
A
I
L
K
E
E
G
V
T
R
Y
P
V
C
R
K
N
K
D
D
I
L
G
F
V
H
I
R
D
L
--
Y
N
Q
K
I
N
E
---
N
--
K
I
E
L
E
E
I
L
R
----
D
I
I
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
--------
D
E
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
-
G
E
I
--------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
79.31
41%
-85
- C1 -
3LV9
1
?
A:
[18-147]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
F
E
E
K
K
I
R
E
I
M
V
P
R
T
D
M
V
C
I
Y
E
S
D
S
E
E
K
I
-
L
A
I
L
K
E
E
G
V
T
R
Y
P
V
C
R
K
N
K
D
D
I
L
G
F
V
H
I
R
D
L
--
Y
N
Q
K
I
N
E
N
-
K
I
----
E
L
E
E
I
L
R
----
D
I
I
Y
I
S
E
N
L
T
I
D
K
A
L
E
R
I
R
K
E
K
L
Q
L
A
I
V
V
--------
D
E
Y
G
G
T
S
G
V
V
T
I
E
D
I
L
E
E
I
V
-
G
E
I
--------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
77.19
36%
-93
- C1 -
3OI8
4
?
A:
[29-156]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
K
V
L
D
F
S
D
L
E
V
R
D
A
M
I
T
R
S
R
M
N
V
L
K
E
N
D
S
I
E
R
I
-
T
A
Y
V
I
D
T
A
H
S
R
F
P
V
I
G
E
D
K
D
E
V
L
G
I
L
H
A
K
D
L
--
L
-
K
Y
M
F
N
P
-
E
Q
--
F
-
H
L
K
S
I
L
R
----
P
A
V
F
V
P
E
G
K
S
L
T
A
L
L
K
E
F
R
E
Q
R
N
H
M
A
I
V
I
--------
D
E
Y
G
G
T
S
G
L
V
T
F
E
D
I
I
E
---------------------------------------------------------------------------------------------------------
61
HHSearch
72.22
34%
-90
- C1 -
3NQR
1
CORC_SALTY
A:
[3-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
Q
T
L
D
E
C
-
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
S
E
D
K
D
H
I
E
G
I
L
M
A
K
D
L
--
L
P
F
M
R
S
D
A
--
E
--
A
F
S
M
D
K
V
L
R
----
T
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
--------
D
E
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
-------------------------------------------------------------------------------------------------------
60
HHSearch
71.61
35%
-85
- C1 -
3LFR
2
?
A:
[3-125]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
V
R
D
I
M
V
P
R
S
Q
M
I
S
I
K
A
T
Q
T
P
R
E
F
-
L
P
A
V
I
D
A
A
H
S
R
Y
P
V
I
G
E
S
H
D
D
V
L
G
V
L
L
A
K
D
L
--
L
P
L
I
L
K
A
D
-
G
D
--
S
D
D
V
K
K
L
L
R
----
P
A
T
F
V
P
E
S
K
R
L
N
V
L
L
R
E
F
R
A
N
H
N
H
M
A
I
V
I
--------
D
E
Y
G
G
V
A
G
L
V
T
I
E
D
V
L
E
Q
I
-------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
71.59
33%
-84
- C1 -
3LFR
2
?
A:
[3-125]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
V
R
D
I
M
V
P
R
S
Q
M
I
S
I
K
A
T
Q
T
P
R
E
F
-
L
P
A
V
I
D
A
A
H
S
R
Y
P
V
I
G
E
S
H
D
D
V
L
G
V
L
L
A
K
D
L
--
L
P
L
I
L
K
A
D
G
D
S
--
D
-
D
V
K
K
L
L
R
----
P
A
T
F
V
P
E
S
K
R
L
N
V
L
L
R
E
F
R
A
N
H
N
H
M
A
I
V
I
--------
D
E
Y
G
G
V
A
G
L
V
T
I
E
D
V
L
E
Q
I
-------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
71.40
32%
-88
- C1 -
3NQR
1
CORC_SALTY
A:
[3-124]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
R
V
R
D
I
M
I
P
R
S
Q
M
I
T
L
K
R
N
Q
T
L
D
E
C
-
L
D
V
I
I
E
S
A
H
S
R
F
P
V
I
S
E
D
K
D
H
I
E
G
I
L
M
A
K
D
L
--
L
P
F
M
R
S
D
A
-
E
A
--
F
-
S
M
D
K
V
L
R
----
T
A
V
V
V
P
E
S
K
R
V
D
R
M
L
K
E
F
R
S
Q
R
Y
H
M
A
I
V
I
--------
D
E
F
G
G
V
S
G
L
V
T
I
E
D
I
L
E
L
I
-------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
71.09
31%
-89
- C1 -
3JTF
4
?
A:
[4-128]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
T
V
A
D
I
M
V
P
R
S
R
M
D
L
L
D
I
S
Q
P
L
P
Q
L
-
L
A
T
I
I
E
T
A
H
S
R
F
P
V
Y
E
D
D
R
D
N
I
I
G
I
L
L
A
K
D
L
--
L
-
R
Y
M
L
E
P
-
A
L
----
D
I
R
S
L
V
R
----
P
A
V
F
I
P
E
V
K
R
L
N
V
L
L
R
E
F
R
A
S
R
N
H
L
A
I
V
I
--------
D
E
-
G
G
I
S
G
L
V
T
M
E
D
V
L
E
Q
I
V
-
G
D
I
--------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
70.79
26%
-76
- C1 -
4IY4
-
CNNM2_HUMAN
A:
[3-152]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
G
E
A
I
L
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
AF
V
D
P
D
D
C
T
P
-
L
K
--
T
-
I
T
K
F
Y
N
H
----
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
F
Y
E
V
L
G
I
V
I
L
E
D
V
I
E
E
I
I
K
S
E
---------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
70.74
27%
-82
- C1 -
4IYS
-
A:
[3-156]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
G
E
A
I
L
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
AF
V
D
P
D
D
C
T
P
-
L
K
--
T
-
I
T
K
F
Y
N
H
----
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
VNNEGE-
D
P
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
K
S
E
I
L
D
E
-----------------------------------------------------------------------------------------------
20
PsiBlast_PDB
70.09
25%
-105
- C1 -
4IY3
-
CNNM4_HUMAN
B:
[3-147]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
Q
L
Q
D
C
F
M
I
R
S
D
A
I
L
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
D
E
Q
S
N
I
V
D
I
L
Y
V
K
D
L
AF
V
D
P
D
D
C
T
P
--------
L
K
T
I
T
R
F
YN
H
P
V
H
F
V
F
H
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
K
V
N
NEG--
D
P
F
Y
E
V
L
G
L
V
T
L
E
D
V
I
E
E
I
I
K-----------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
69.99
27%
-94
- C1 -
3LHH
1
?
A:
[43-165]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
S
L
M
V
P
R
S
D
I
V
F
L
D
L
N
L
P
L
D
A
N
-
L
R
T
V
M
Q
S
P
H
S
R
F
P
V
C
R
N
N
V
D
D
M
V
G
I
I
S
A
K
Q
L
--
L
S
E
S
I
A
G
E
-
R
L
----
E
L
V
D
L
V
K
----
N
C
N
F
V
P
N
S
L
S
G
M
E
L
L
E
H
F
R
T
T
G
S
Q
M
V
F
V
V
--------
D
E
Y
G
D
L
K
G
L
V
T
L
Q
D
M
M
D
A
L
T
-
G
E
F
F
-------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
69.79
27%
-74
- C1 -
3OCM
7
?
A:
[23-166]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
N
M
V
S
G
V
L
T
L
A
E
R
S
I
R
S
I
M
T
P
R
T
D
V
S
W
V
N
I
D
D
D
A
A
T
I
-
R
Q
Q
L
T
A
A
P
H
S
F
F
P
V
C
R
G
S
L
D
E
V
V
G
I
G
R
A
K
D
L
--
V
A
D
L
I
T
E
G
-
R
V
--
R
---
R
N
R
L
R
----
D
P
I
I
V
H
E
S
I
G
I
L
R
L
M
D
T
L
K
R
S
R
G
Q
L
V
L
V
A
--------
D
E
F
G
A
I
E
G
L
V
T
P
I
D
V
F
E
A
I
A
-
G
E
F
P
D
E
D
E
L
P
-------------------------------------------------------------------------------------------
13
PsiBlast_PDB
68.89
27%
-78
- C1 -
4IY0
4
A:
[6-152]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
G
E
A
I
L
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
AF
V
D
P
D
D
C
T
P
-
L
K
--
T
-
I
T
K
F
Y
N
H
----
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
K
S
E
---------------------------------------------------------------------------------------------------
40
HHSearch
68.39
27%
-93
- C1 -
3LHH
1
?
A:
[43-167]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
S
S
L
M
V
P
R
S
D
I
V
F
L
D
L
N
L
P
L
D
A
N
-
L
R
T
V
M
Q
S
P
H
S
R
F
P
V
C
R
N
N
V
D
D
M
V
G
I
I
S
A
K
Q
L
--
L
S
E
S
I
A
G
---
E
--
R
L
E
L
V
D
L
V
K
----
N
C
N
F
V
P
N
S
L
S
G
M
E
L
L
E
H
F
R
T
T
G
S
Q
M
V
F
V
V
--------
D
E
Y
G
D
L
K
G
L
V
T
L
Q
D
M
M
D
A
L
T
-
G
E
F
F
-------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
68.03
25%
-79
- C1 -
4P1G
1
A:
[3-149]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
N
I
I
Q
G
A
L
E
L
R
T
K
T
V
E
D
V
M
T
P
L
R
D
C
F
M
I
T
G
E
A
I
L
D
F
N
T
M
S
E
I
M
E
S
G
Y
T
R
I
P
V
F
E
G
E
R
S
N
I
V
D
L
L
F
V
K
D
L
AF
V
D
P
D
D
C
T
P
-
L
K
--
T
-
I
T
K
F
Y
N
H
----
P
L
H
F
V
F
N
D
T
K
L
D
A
M
L
E
E
F
K
K
G
K
S
H
L
A
I
V
Q
R
V
N
NEGE
G
D
P
F
Y
E
V
L
G
I
V
T
L
E
D
V
I
E
E
I
I
-
K
S
E
--------------------------------------------------------------------------------------------------
63
Fugue
67.92
28%
-95
- C1 -
3HF7
1
?
A:
[1-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
S
V
N
D
I
M
V
P
R
N
E
I
V
G
I
D
I
N
D
D
W
K
S
I
-
V
R
Q
L
T
H
S
P
H
G
R
I
V
L
Y
R
D
S
L
D
D
A
I
S
M
L
R
V
R
E
A
--
Y
R
L
M
T
E
K
K
-
E
F
T
K
E
-
I
M
L
R
A
A
D
----
E
I
Y
F
V
P
E
G
T
P
L
S
T
Q
L
V
K
F
Q
R
N
K
K
K
V
G
L
V
V
--------
D
E
Y
G
D
I
Q
G
L
V
T
V
E
D
I
L
E
E
I
V
-
G
----------------------------------------------------------------------------------------------------
42
HHSearch
67.91
25%
-69
- C1 -
3OCM
7
?
A:
[18-164]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
G
V
E
E
R
N
M
V
S
G
V
L
T
L
A
E
R
S
I
R
S
I
M
T
P
R
T
D
V
S
W
V
N
I
D
D
D
A
A
T
I
-
R
Q
Q
L
T
A
A
P
H
S
F
F
P
V
C
R
G
S
L
D
E
V
V
G
I
G
R
A
K
D
L
--
V
A
D
L
I
T
E
G
-------
R
V
R
R
N
R
L
R
---
D
P
I
I
V
H
E
S
I
G
I
L
R
L
M
D
T
L
K
R
S
R
G
Q
L
V
L
V
A
--------
D
E
F
G
A
I
E
G
L
V
T
P
I
D
V
F
E
A
I
A
-
G
E
F
P
D
E
D
E
L
P
-------------------------------------------------------------------------------------------