@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0001: (2016-03-11 )
VQSIEDIWQETLQIVKKNMSKPSYDTWMKSTTAHSLEGNTFIISAPNNFVRDWLEKSYTQFIANILQEITGRLFDVRFIDGEQEENFEYTVIKPNPALDEDGIEIGKHMLNPRYVFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAVGHYVQQHKDNAKVMYLSSEKFTNEFISSIRDNKTEEFRTKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNTLYDEQKQIIISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKADGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLVNKDITAGLAAEALKDIIPSSKSQVITISGIQEAVGEYFHVRLEDFKAKKRTKSIAFPRQIAMYLSRELTDASLPKIGDEFGGRDHTTVIHAHEKISQLLKTDQVLKNDLAEIEKNLRKAQNMF
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180......-.190.......200.-..-.-...210.......220.......230......--------.240........250.......260.......270.......280.......290.......300.......310....--...320.......-330.......340.......350....-...360.......370.......380.......390.......400.......410.......420.......430.......440.......450
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
VQ
S
I
E
D
I
W
Q
E
T
L
Q
I
V
K
K
NMSKP
S
Y
D
T
W
M
KSTTAHSLEG
N
T
F
I
I
SA
P
N
N
F
V
R
D
W
L
E
K
S
Y
T
Q
F
I
A
N
I
L
Q
E
I
TG
R
L
F
D
V
R
FIDGEQEENF
E
Y
T
V
IKPNPALDE
D
G
I
E
I
G
K
H
MLNP
R
Y
V
F
D
T
F
V
IGSGNR
F
A
H
A
A
S
L
A
VAEAPAKAY
N
P
L
F
I
YGGVGL
G
K
T
H
L
M
H
A
V
G
H
Y
V
Q
Q
HKDN
A
K
V
M
Y
L
S
S
E
K
F
T
N
E
F
-
I
S
S
I
RDN
K
T
E
E
F
R
T
K
-YR-N-V
D
V
L
L
IDD
I
Q
F
L
AGKEG
T
Q
E
E
F
F
H
T
F
N
T
L
Y
D
E
--------
Q
K
-
Q
I
I
ISSDRPPKEIP
T
L
E
D
R
L
R
S
R
FEWGLITDITPP
D
L
E
T
R
I
A
I
L
R
K
K
AKADGLDI
P
N
E
V
M
L
Y
I
A
N
Q
ID
S
N
I
R
E
L
E
G
--
A
L
I
R
V
V
A
Y
S
S
L
VN-
K
D
I
T
A
G
L
A
A
E
A
L
K
D
IIPSSKS
Q
V
I
T
I
S
-
G
I
Q
E
A
V
G
E
Y
F
H
V
R
L
E
D
F
K
AKKRTKSIA
F
P
R
Q
I
A
M
Y
L
S
R
ELTDASLPK
I
G
D
E
FGGRDH
T
T
V
I
H
A
H
E
K
I
S
Q
L
L
K
T
D
Q
V
L
K
N
D
L
A
E
I
E
K
N
L
R
K
A
QNMF
42
HHSearch
87.04
39%
-91
- C2 -
1L8Q
2
DNAA_AQUAE
A:
[2-322]
-----------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
K
R
--
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
E
L
-
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
--
K
I
K
L
I
K
L
K
G
F
E
G
L
-
E
--
R
---
K
----------
E
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
R
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
K
--
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
----
31
Fugue
86.25
38%
-92
- C2 -
1L8Q
2
DNAA_AQUAE
A:
[2-324]
-----------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
K
--
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
-
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
--
K
I
K
L
I
K
L
K
G
-----------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
R
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
K
R
K
--
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
--
5
PsiBlast_PDB
85.02
38%
-89
- C2 -
1L8Q
2
DNAA_AQUAE
A:
[2-317]
-----------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
--
E
A
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
F
E
G
L
E
R
-
K
E
-----------------
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
R
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
K
--
R
K
F
K
H
L
V
G
F
L
E
K
---------
23
PsiBlast_CBE
84.60
38%
-88
- C2 -
3R8F
3
DNAA_AQUAE
D:
[2-317]
-----------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
--
E
A
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-
K
E
-----------------
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
---
R
K
F
K
H
L
V
G
F
L
E
K
---------
24
PsiBlast_CBE
84.45
38%
-87
- C2 -
3R8F
4
DNAA_AQUAE
C:
[2-317]
-----------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
--
E
A
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-
K
E
-----------------
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
---
R
K
F
K
H
L
V
G
F
L
E
K
---------
25
PsiBlast_CBE
84.01
38%
-86
- C2 -
3R8F
4
DNAA_AQUAE
B:
[2-317]
-----------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
--
E
A
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-
K
E
-----------------
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
---
R
K
F
K
H
L
V
G
F
L
E
K
---------
3
PsiBlast_PDB
83.63
38%
-87
- C2 -
3R8F
4
DNAA_AQUAE
A:
[2-317]
-----------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
--
E
A
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
F
E
G
L
E
R
-
K
E
-----------------
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
---
R
K
F
K
H
L
V
G
F
L
E
K
---------
26
PsiBlast_CBE
83.30
38%
-86
- C2 -
2HCB
2
DNAA_AQUAE
D:
[2-316]
------------------------------------------------------------------------------------------------------------
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
--
E
A
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-
K
E
-----------------
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
K
--
R
K
F
K
H
L
V
G
F
L
E
K
---------
4
PsiBlast_PDB
82.46
38%
-87
- C2 -
2HCB
3
DNAA_AQUAE
A:
[2-316]
------------------------------------------------------------------------------------------------------------
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
--
E
A
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
F
E
G
L
E
R
-
K
E
-----------------
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
R
--
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
--
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
K
--
R
K
F
K
H
L
V
G
F
L
E
K
---------
22
PsiBlast_CBE
82.37
37%
-102
- C2 -
2Z4R
2
DNAA_THEMA
B:
[96-335]
---------------------------------------------------------------------------------------------------
T
P
--------
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
-
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
-
Y
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
---------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
82.26
38%
-84
- C2 -
2HCB
3
DNAA_AQUAE
C:
[2-316]
------------------------------------------------------------------------------------------------------------
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
--
E
A
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
KI
K
L
I
K
L
K
G
F
E
G
L
E
R
-
K
E
-----------------
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
---
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
K
--
R
K
F
K
H
L
V
G
F
L
E
K
---------
1
PsiBlast_PDB
82.15
37%
-102
- C2 -
2Z4R
2
DNAA_THEMA
A:
[96-335]
---------------------------------------------------------------------------------------------------
T
P
--------
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
-
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
-
Y
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
---------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
82.05
37%
-102
- C2 -
2Z4R
2
DNAA_THEMA
C:
[96-335]
---------------------------------------------------------------------------------------------------
T
P
--------
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
-
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
-
Y
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
---------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
81.50
37%
-103
- C2 -
2Z4S
2
DNAA_THEMA
A:
[96-335]
---------------------------------------------------------------------------------------------------
T
P
--------
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
-
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
-
Y
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
---------------------------------------------------------------------------------------------------------
41
HHSearch
81.19
37%
-105
- C2 -
2Z4S
2
DNAA_THEMA
A:
[96-335]
-----------------------------------------------------------------------------------------------------------
T
P
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
-
R
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
D
L
R
V
M
Y
I
T
S
E
K
F
L
N
D
L
-
V
D
S
M
K
E
G
K
L
N
E
F
R
E
K
-
Y
R
K
K
-
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
--------
G
K
-
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
--
A
I
I
K
L
L
V
Y
K
E
T
T
G
-
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
K
P
---------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
80.78
38%
-82
- C2 -
2HCB
3
DNAA_AQUAE
B:
[2-316]
------------------------------------------------------------------------------------------------------------
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
--
E
A
K
K
R
G
Y
R
V
I
Y
S
S
A
D
D
F
A
Q
A
M
-
V
E
H
L
K
K
G
T
I
N
E
F
R
N
M
-
Y
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
--------
E
K
-
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
T
-
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
F
E
G
L
E
R
-
K
E
-----------------
R
K
E
R
D
K
L
M
-
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
--
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
K
--
R
K
F
K
H
L
V
G
F
L
E
K
---------
11
PsiBlast_PDB
55.62
24%
-76
- C2 -
3BOS
13
?
A:
[45-241]
---------------------------------------------------------------------------------------------------------------------------------------
S
A
A
S
G
D
G
V
Q
A
I
Y
L
W
G
P
V
K
S
G
R
T
H
L
I
H
A
A
C
A
R
A
N
E
L
E
R
R
S
F
Y
I
P
L
G
----
I
H
A
S
-
I
S
T
A
L
L
E
G
L
E
Q
F
----------
D
L
I
C
I
D
D
V
D
A
V
A
G
H
P
L
W
E
E
A
I
F
D
L
Y
N
R
V
A
E
Q
--------
K
R
G
S
L
I
V
S
A
S
A
S
P
M
E
A
G
F
V
L
P
D
L
V
S
R
M
H
W
G
L
T
Y
Q
L
Q
P
M
M
D
D
E
K
L
A
A
L
Q
R
R
A
A
M
R
G
L
Q
L
P
E
D
V
G
R
F
L
L
N
R
M
A
R
D
L
R
T
L
F
D
--
V
L
D
R
L
D
K
A
S
M
V
H
Q
-
R
K
L
T
I
P
F
V
K
E
M
L
R
--------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
54.56
24%
-75
- C2 -
3SC3
2
?
A:
[28-224]
---------------------------------------------------------------------------------------------------------------------------------------
S
A
A
S
G
D
G
V
Q
A
I
Y
L
W
G
P
V
K
S
G
R
T
H
L
I
H
A
A
C
A
R
A
N
E
L
E
R
R
S
F
Y
I
P
L
G
----
I
H
A
S
-
I
S
T
A
L
L
E
G
L
E
Q
F
----------
D
L
I
C
I
D
D
V
D
A
V
A
G
H
P
L
W
E
E
A
I
F
D
L
Y
N
R
V
A
E
Q
--------
K
R
G
S
L
I
V
S
A
S
A
S
P
M
E
A
G
F
V
L
P
D
L
V
S
R
M
H
W
G
L
T
Y
Q
L
Q
P
M
M
D
D
E
K
L
A
A
L
Q
R
R
A
A
M
R
G
L
Q
L
P
E
D
V
G
R
F
L
L
N
R
M
A
R
D
L
R
T
L
F
D
--
V
L
D
R
L
D
K
A
S
M
V
H
Q
-
R
K
L
T
I
P
F
V
K
E
M
L
R
--------------------------------------------------------------------------------------------------------------
61
HHSearch
52.56
21%
-86
- C2 -
3PFI
1
?
A:
[27-251]
------------------------------------------------------------------------------------------------------------------
N
F
D
G
Y
I
G
Q
E
S
I
K
K
N
L
N
V
F
I
A
A
A
K
K
R
N
E
C
L
D
H
I
L
F
S
G
P
A
G
L
G
K
T
T
L
A
N
I
I
S
Y
E
M
S
A
-----
N
I
K
T
T
A
A
P
M
I
E
K
---
S
G
-----
D
L
A
A
I
L
T
N
-
L
S
-
E
-
G
D
I
L
F
I
D
E
I
H
R
L
S
P
A
--
I
E
E
V
L
Y
P
A
M
E
D
Y
R
L
-A
Q
T
I
K
I
D
L
P
K
-
F
T
L
I
G
A
T
T
R
A
G
---
M
L
S
N
P
L
R
D
R
F
G
M
--
Q
F
R
L
E
F
Y
K
D
S
E
L
A
L
I
L
Q
K
A
A
L
K
L
N
K
T
C
E
E
K
A
A
L
E
I
A
K
R
S
R
S
T
P
R
I
A
L
R
--
L
L
K
R
V
R
D
F
A
D
V
N
D
E
E
I
I
T
E
K
R
A
N
E
A
L
---------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
52.00
48%
-98
- C1 -
4TPS
-
DNAA_BACSU
B:
[4-82]
M
E
N
I
L
D
L
W
N
Q
A
L
A
Q
I
E
K
K
L
S
K
P
S
F
E
T
W
M
K
S
T
K
A
H
S
L
Q
G
D
T
L
T
I
T
A
P
N
E
F
A
R
D
W
L
E
S
R
Y
L
H
L
I
A
D
T
I
Y
E
L
T
G
E
E
L
S
I
K
F
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------