@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0326: (2016-03-14 )
MISYGELIRQIRQSKKISQKEVYTGVISKSYAIEFEKGTHAISSLLLEKIVAKLMVSMEEFFLMYHQEALPEKEDFWEAYARTCKTDEASAWESLYQKISLEKGKVNQVKSAAIKLELDHIKGKQVADKKAVQILENYLIEAVFWTLQDIFLFTRMMHYLPLKSRVPFYYKLLNTLDRYRHFERGRSISQSALASIMDDFIEKNEIEYMELMIKSLEKISEDCDGTYSKILCMYYRGIVRWREGEKREGSEEIEQAVAILRALGYENKAAEYETMYRQFARENNDIKTME
Atome Classification :
(20 SA)
----------.........10........-20.-..-..-...30.......-.40------.........50........60.....---------------...70........80.......-.90........100---....---...-------------------------110.......120.......130.......140----....---------...150.---......-----160--.........170.......180..----.....190.......200...--....210.......220.......230..----------.....240.------..-.-...250.......260.-.....---.270......--------.280.......290--------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------MI
S
Y
G
E
L
I
R
Q
I
R
Q
SKKI
S
Q
-
K
E
V
-
Y
T
-GV-ISK
S
Y
A
I
E
FEK
G
-
T
H
-------
A
I
S
S
L
L
L
E
K
I
V
A
K
L
M
V
S
M
E
E
F
F
L
M
Y
H
---------------
Q
E
ALP
E
K
E
D
F
W
E
A
Y
A
R
TCKTD
E
-
A
S
A
W
E
S
L
Y
Q
K
ISLE---KGK
V
---
N
Q
V-------------------------K
S
A
A
I
K
L
E
L
DHIKGKQV
A
D
K
K
A
V
Q
I
L
E
N
Y
L
I
E
A
----
V
F
W
T
---------
L
Q
D
I
F
L
F
---
T
R
M
M
H
Y-----L----PLKSRV
P
F
Y
Y
K
L
L
N
T
L
D
R
Y
R
H
F
E
R----GRSI
S
Q
S
A
L
A
S
I
M
D
D
F
I
EKN
E
--
I
E
Y
M
E
L
M
I
K
S
L
E
K
I
S
E
DCD
G
T
Y
S
K
I
L
C
M
Y
----------
Y
R
G
I
V
RWRE------GE-K-RE
G
S
E
E
I
E
Q
A
V
A
I
L
R
AL-GYENK---A
A
E
Y
E
T
M
Y
R
Q
--------
F
A
RENNDIKTME----------------------
16
HHSearch
75.53
14%
-93
- C4 -
3U3W
4
?
A:
[3-282]
----------
A
E
K
L
G
S
E
I
K
K
I
R
V
L
R
G
L
T
Q
-
K
Q
L
-
S
E
-
N
I
-
C
H
Q
S
E
V
S
R
I
E
S
G
-
A
V
-------
Y
P
S
M
D
I
L
Q
G
I
A
A
K
L
Q
I
P
I
I
H
F
Y
E
V
L
I
---------------
Y
S
D
I
E
R
K
K
Q
F
K
D
Q
V
I
M
L
C
K
Q
K
R
-
Y
K
E
I
Y
N
K
V
W
N
E
L
K
K
EEY
H
P
E
F
Q
Q
F
L
Q
W
-------------------------
Q
Y
Y
V
A
A
Y
V
L
-
K
K
--
V
--
D
Y
E
Y
C
I
L
E
L
K
K
L
L
N
Q
Q
LTGI
D
V
Y
Q
-----------
N
L
Y
I
E
---
N
A
I
A
N
I
-----
Y
A
E
N
G
Y
L
K
K
G
I
D
L
F
E
Q
I
L
K
Q
L
E
A
L
H
---
D
----
N
E
E
F
D
V
K
V
R
Y
N
H
A
K
A
L
Y
L
D
S
R
--
Y
E
E
S
L
Y
Q
V
N
K
A
I
E
I
S
C
R
I
N
S
M
A
L
I
G
Q
L
Y
Y
----------
Q
R
G
E
C
L
R
K
L
------
E
Y
-
E
E
A
E
I
E
D
A
Y
K
K
A
S
F
F
F
D
I
L
-
E
M
H
A
Y
---
K
E
A
L
V
N
K
---------------------------------------------
40
Fugue
69.01
11%
-76
- C4 -
2QFC
4
?
A:
[3-286]
----------
A
E
K
L
G
S
E
I
K
K
I
R
V
L
R
G
L
T
Q
-
K
Q
L
-
S
E
-
N
I
-
C
H
Q
S
E
V
S
R
I
E
S
G
-
A
V
-------
Y
P
S
M
D
I
L
Q
G
I
A
A
K
L
Q
I
P
I
I
H
F
Y
E
V
L
I
---------------
Y
S
D
I
E
R
K
K
Q
F
K
D
Q
V
I
M
L
C
K
Q
K
R
-
Y
K
E
I
Y
N
K
V
W
N
E
L
K
K
---
E
E
Y
H
---
P
E
F
-------------------------
Q
Q
F
L
Q
W
Q
Y
Y
V
A
A
Y
V
L
K
K
V
D
Y
E
Y
C
I
L
E
L
K
K
L
L
N
Q
----
Q
L
T
G
---------
I
D
V
Y
Q
N
L
---
Y
I
E
N
A
I
-----
A
----
N
I
Y
A
E
N
G
Y
L
K
K
G
I
D
L
F
E
Q
I
L
K
Q
L
E
A
L
HD
N
E
E
F
D
V
K
V
R
Y
N
H
A
K
A
L
Y
L
D
S
R
--
Y
E
E
S
L
Y
Q
V
N
K
A
I
E
I
S
C
R
I
N
S
M
A
L
I
G
Q
L
Y
Y
----------
Q
R
G
E
C
L
R
K
L
------
E
Y
E
E
-
A
E
I
E
D
A
Y
K
K
A
S
F
F
F
D
I
L
-
E
M
H
A
Y
---
K
E
A
L
V
N
K
I
S
R
--------
L
---------------------------------
46
Fugue
67.74
14%
-59
- C2 -
4O5J
3
?
A:
[27-400]
LKN
L
N
E
K
Y
E
Q
L
S
Q
Y
L
N
Q
V
A
S
L
K
Q
S
I
Q
N
A
N
-
N
I
E
-
L
V
-
N
S
-
S
L
N
Y
L
K
S
F
T
N
N
N
-
Y
N
-------
S
T
T
Q
S
P
I
F
N
A
V
Q
A
V
I
T
S
V
L
G
F
W
S
L
Y
A
GNYFTFFVGKKVD
S
G
Q
P
A
S
V
Q
G
N
P
P
F
K
T
I
I
E
N
C
S
G
I
E
N
C
A
M
D
Q
T
T
Y
D
K
M
K
K
L
---
A
E
D
L
---
Q
A
A
Q
TNSATKGNNLCALSGCAATSNPPN
S
T
V
S
N
A
L
N
L
A
Q
Q
L
M
D
L
I
A
N
T
K
T
A
M
M
W
K
N
I
V
I
S
G
----
V
S
N
T
SGAIT
S
T
N
Y
P
T
Q
Y
A
V
F
---
N
N
I
K
A
M
-----
I
----
P
I
L
Q
Q
A
V
T
L
S
Q
S
N
H
T
L
S
A
S
L
Q
A
Q
A
----
T
G
S
Q
T
N
P
K
F
A
K
D
I
Y
T
F
A
Q
N
Q
K
Q
V
I
S
Y
A
Q
D
I
F
N
L
F
N
S
I
P
A
E
Q
Y
K
Y
L
E
K
A
Y
L
K
I
PNAGSTPTNP
Y
R
Q
V
V
N
L
N
Q
E
V
Q
T
I
K
N
N
-
V
-
S
Y
Y
G
N
R
V
D
A
A
L
S
V
A
R
D
V
Y
N
L
K
S
N
---
Q
A
E
I
V
T
A
Y
N
D
--------
A
K
T
L
S
E
E
I
S
K
L
P
H---------------------
42
Fugue
62.67
15%
-52
- C3 -
4Q0W
4
RAD2_YEAST
A:
[1-362]
---------G
V
H
S
F
W
D
I
A
G
P
T
A
R
P
V
R
L
E
S
L
E
D
K
-
R
M
-
A
V
-
D
A
S
I
W
I
Y
Q
F
L
K
A
-
V
R
DQNAVKN
S
H
I
T
G
F
F
R
R
I
C
K
L
L
Y
F
G
I
R
P
V
F
V
F
D
G
---------------
G
V
P
V
L
K
R
E
T
I
R
Q
R
K
E
R
R
Q
G
K
R
E
-
D
E
----------
V
T
---
M
D
M
I
---
K
E
V
-------------------------
Q
E
L
L
S
R
F
G
I
P
Y
I
T
A
P
M
E
A
E
A
Q
C
A
E
L
L
Q
L
N
L
V
D
G
----
I
I
T
D
---------
D
S
D
V
F
L
F
GG-
T
K
I
Y
K
N
-----
M
----
F
H
E
K
N
Y
V
E
F
Y
D
-
A
E
S
I
L
K
L
L
G
L
D
R
----
K
N
M
I
E
L
A
Q
L
L
G
--
S
D
Y
--
T
N
G
--
L
K
G
M
G
-
P
V
S
S
I
E
V
I
A
E
F
--
G
N
L
K
N
F
K
D
W
Y
----------
N
N
G
Q
F
D
K
R
K
------
Q
E
-
T
-
E
N
K
F
E
K
D
L
R
K
K
L
V
N
N
E
I
-
I
L
D
D
D
FPS
V
M
V
Y
D
A
Y
M
R
P
EVDHDT
T
P
F
V
W
G
V
P
D
L
D
M
L
R
S
F
M
K
T
Q
LGWP
H
E
K
S
D
E
I
L
I
PLI
1
PsiBlast_PDB
62.66
21%
-30
- C4 -
4YV9
5
?
A:
[6-272]
--------------
G
K
T
L
R
R
L
R
Q
G
K
Q
V
S
I
-
S
S
L
-------
L
S
K
S
Q
I
S
R
F
E
R
G
-
E
S
-------
E
I
S
C
S
R
L
L
N
L
L
D
K
L
N
I
T
I
D
E
F
V
S
T
------------------------
T
H
F
F
T
L
L
S
R
V
R
K
Y
Y
A
-
E
K
N
V
A
K
L
L
K
L
--
L
E
---
D
Y
A
H
---
K
D
Y
-------------------------
E
S
T
M
I
K
A
I
L
S
S
I
E
P
T
V
E
P
S
E
E
E
V
T
R
L
T
D
Y
L
F
S
V
----
E
Q
W
G
---------
Y
Y
E
I
I
L
L
G
N
C
S
R
F
I
N
Y
N
T
L
F
L
L
----
T
K
E
M
V
T
S
F
A
Y
S
E
Q
N
K
T
N
K
-----------
T
L
V
T
Q
L
S
I
N
C
L
I
I
S
-
I
D
Y
S
Y
--
F
D
H
S
H
Y
L
I
E
K
I
E
F
L
L
R
D
E
L
N
F
Y
E
K
T
V
F
L
Y
----------
V
H
G
Y
Y
K
L
K
Q
------
G
Q
-
V
--
S
G
K
D
D
M
R
Q
A
L
Q
I
F
K
Y
L
-
G
E
D
A
L
---
Y
Y
S
Y
K
E
H
Y
R
K
------------------------------------------
31
HHSearch
61.91
30%
-89
- C4 -
3QQ6
-
SINR_BACSU
A:
[-1-64]
-----------
H
M
I
G
Q
R
I
K
Q
Y
R
K
E
K
G
Y
S
L
-
S
E
L
-
A
E
-
K
A
G
V
A
K
S
Y
L
S
S
I
E
R
N
L
Q
T
-------
N
P
S
I
Q
F
L
E
K
V
S
A
V
L
D
V
S
V
H
T
L
L
D
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
61.00
35%
-74
- C4 -
2GRM
-
?
A:
[1-60]
----------
M
F
K
I
G
S
V
L
K
Q
I
R
Q
E
L
N
Y
H
Q
-
I
D
L
-
Y
S
-
G
I
-
M
S
K
S
V
Y
I
K
V
E
A
D
-
S
R
-------
P
I
S
V
E
E
L
S
K
F
S
E
R
L
G
V
N
F
F
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
59.06
30%
-85
- C4 -
2B5A
1
?
A:
[11-76]
-------------
F
G
R
T
L
K
K
I
R
T
Q
K
G
V
S
Q
-
E
E
L
-
A
D
L
A
G
-
L
H
R
T
Y
I
S
E
V
E
R
G
-
D
R
-------
N
I
S
L
I
N
I
H
K
I
C
A
A
L
D
I
P
A
S
T
F
F
R
K
M
E
---------------
E
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
58.49
31%
-75
- C4 -
1B0N
4
SINR_BACSU
A:
[1-71]
------------
M
I
G
Q
R
I
K
Q
Y
R
K
E
K
G
Y
S
L
-
S
E
L
-
A
E
-
K
A
G
V
A
K
S
Y
L
S
S
I
E
R
N
L
Q
T
-------
N
P
S
I
Q
F
L
E
K
V
S
A
V
L
D
V
S
V
H
T
L
L
D
E
K
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
57.78
35%
-64
- C4 -
2AXV
-
?
A:
[2-60]
-----------
F
K
I
G
S
V
L
K
Q
I
R
Q
E
L
N
Y
H
Q
-
I
D
L
-
Y
S
-
G
I
-
M
S
K
S
V
Y
I
K
V
E
A
D
-
S
R
-------
P
I
S
V
E
E
L
S
K
F
S
E
R
L
G
V
N
F
F
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
57.66
35%
-68
- C4 -
2GRL
-
?
A:
[1-60]
----------
M
F
K
I
G
S
V
L
K
Q
I
R
Q
E
L
N
Y
H
Q
-
I
D
L
-
Y
S
-
G
I
-
M
S
K
S
V
Y
I
K
V
E
A
D
-
S
R
-------
P
I
S
V
E
E
L
S
K
F
S
E
R
L
G
V
N
F
F
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
57.14
23%
-82
- C4 -
3U3W
4
?
A:
[7-98]
--------------
G
S
E
I
K
K
I
R
V
L
R
G
L
T
Q
-
K
Q
L
-
S
E
-
N
I
-
C
H
Q
S
E
V
S
R
I
E
S
G
-
A
V
-------
Y
P
S
M
D
I
L
Q
G
I
A
A
K
L
Q
I
P
I
I
H
F
Y
E
V
L
I
---------------
Y
S
D
I
E
R
K
K
Q
F
K
D
Q
V
I
M
L
C
K
Q
----
K
R
Y
K
E
I
Y
N
K
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
56.90
30%
-88
- C4 -
2B5A
1
?
A:
[9-73]
-----------
R
K
F
G
R
T
L
K
K
I
R
T
Q
K
G
V
S
Q
-
E
E
L
-
A
D
-
L
A
G
L
H
R
T
Y
I
S
E
V
E
R
G
-
D
R
-------
N
I
S
L
I
N
I
H
K
I
C
A
A
L
D
I
P
A
S
T
F
F
R
K
M
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
56.67
35%
-71
- C4 -
2AW6
-
?
A:
[1-60]
----------
M
F
K
I
G
S
V
L
K
Q
I
R
Q
E
L
N
Y
H
Q
-
I
D
L
-
Y
S
-
G
I
-
M
S
K
S
V
Y
I
K
V
E
A
D
-
S
R
-------
P
I
S
V
E
E
L
S
K
F
S
E
R
L
G
V
N
F
F
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
55.88
23%
-71
- C4 -
2QFC
-
?
A:
[7-98]
--------------
G
S
E
I
K
K
I
R
V
L
R
G
L
T
Q
-
K
Q
L
-
S
E
-
N
I
-
C
H
Q
S
E
V
S
R
I
E
S
G
-
A
V
-------
Y
P
S
M
D
I
L
Q
G
I
A
A
K
L
Q
I
P
I
I
H
F
Y
E
V
L
I
---------------
Y
S
D
I
E
R
K
K
Q
F
K
D
Q
V
I
M
L
C
K
Q
----
K
R
Y
K
E
I
Y
N
K
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
54.98
24%
-82
- C4 -
3F52
2
?
A:
[26-93]
----------
R
E
A
L
G
A
A
L
R
S
F
R
A
D
K
G
V
T
L
-
R
E
L
-
A
E
-
A
S
R
V
S
P
G
Y
L
S
E
L
E
R
G
-
R
K
-------
E
V
S
S
E
L
L
A
S
V
C
H
A
L
G
A
S
V
A
D
V
L
I
E
A
A
---------------
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
54.32
22%
-68
- C4 -
2R1J
2
RPC2_BPP22
L:
[3-66]
----------
T
Q
L
M
G
E
R
I
R
A
R
R
K
K
L
K
I
R
Q
-
A
A
L
-
G
K
-
M
V
G
V
S
N
V
A
I
S
Q
W
E
R
S
-
E
T
-------
E
P
N
G
E
N
L
L
A
L
S
K
A
L
Q
C
S
P
D
Y
L
L
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
53.72
35%
-64
- C4 -
2AXZ
1
?
A:
[5-60]
--------------
G
S
V
L
K
Q
I
R
Q
E
L
N
Y
H
Q
-
I
D
L
-
Y
S
-
G
I
-
M
S
K
S
V
Y
I
K
V
E
A
D
-
S
R
-------
P
I
S
V
E
E
L
S
K
F
S
E
R
L
G
V
N
F
F
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
53.64
22%
-66
- C4 -
1ADR
-
RPC2_BPP22
A:
[3-68]
----------
T
Q
L
M
G
E
R
I
R
A
R
R
K
K
L
K
I
R
Q
-
A
A
L
-
G
K
-
M
V
G
V
S
N
V
A
I
S
Q
W
E
R
S
-
E
T
-------
E
P
N
G
E
N
L
L
A
L
S
K
A
L
Q
C
S
P
D
Y
L
L
K
G
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
51.69
23%
-59
- C4 -
1Y7Y
-
?
A:
[11-73]
----------
L
V
K
F
G
Q
R
L
R
E
L
R
T
A
K
G
L
S
Q
-
E
T
L
A
F
L
-
S
G
-
L
D
R
S
Y
V
G
G
V
E
R
G
-
Q
R
-------
N
V
S
L
V
N
I
L
K
L
A
T
A
L
D
I
E
P
R
E
L
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------