@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0352: (2016-03-14 )
MFPFERQNKIIHLLDQNSKITVPELSRILDVSISTIRNDLSSLEESGMIKKVHGGAVLLKSEEKFTNFNDRIIRNIEEKEAIAKEAATLVKNNQTIILDASSTALALAKELHGFSRLTVITSGLYTAIELKDNPNISVILTGGIVTTNSFTLEGILGANLIENIHADLCFMSAKGFTMEEGLTDFNIYETELKRLLAKRTNKLIALLDHTKMGVISTASITSAENIDLLITDNKINKALYKKFQDAGLPVKVAE
Atome Classification :
(20 SA)
.........10......--------.--.20........30........40.......-.50.----.......60..--......-----70........80.......-.----90...-----....-.100...---.....110-.------.--------.....-120.------.-------------...-..130.....-....------140.....---..-.-.-150..-.-....160..-----------.....170.......180...---....----------------------190.-----.-------..-.-..-200.....-..210-----........220.......230----------------........240.......250..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MFPFERQN
K
I
I
H
L
LDQN--------S--KI
T
V
P
E
L
S
R
I
L
D
V
S
I
S
T
I
R
N
D
L
S
S
L
E
ESG
M
-
I
K
KV----HG
G
A
V
L
L
KSEE--KFTNF
N
-----
D
R
I
I
R
N
I
E
E
K
E
A
I
A
K
E
A
A
T
-
L
----VKNN
Q
-----
T
I
I
L
-DA-S
S
T
A
---
L
A
L
A
K
E
L
H-G------F--------SR
L
T
V
-
I
TSG------
L
-------------
Y
T
A
-
I
E
L--KDNP
N
-
I
S
V
I
------
L
--TG
G
I
V
---TT-N-
S
-
F
T
L
E
G
-
I
-
L
G
A
N
L
I
E
N
I
-----------
H
A
D
L
C
F
MSAKGF
T
M
EEGLTDF---N
I
Y
E
----------------------
T
E
L
K
-----
R
-------
L
L
-
A
-
K
R-TN
K
L
I
A
L
L-DHTK------M
G
V
I
S
T
A
SITSAE
N
I
D
L
L
I
T-----------------DNKI
N
K
A
L
Y
K
K
F
Q
DAGLPVKVAE
53
HHSearch
72.76
19%
-97
- C3 -
3RRL
1
SCOB_HELPY
B:
[1-175]
---------------------------------------------------------------------------------------------------
M
R
E
A
I
I
K
R
A
A
K
-
E
----
L
K
E
G
M
-----
Y
V
N
L
-
G
I
-
G
L
P
T
---
L
-
V
A
N
E
V
S
-
G
---------------
M
N
I
V
F
-
Q
S
E
N
------
G
-------------
L
L
G
I
G
A
Y
PL
E
G
S
V
D
-
A
D
L
I
------
N
--
A
G
K
E
T
I
T
V
V
P
-
G
-
A
-
S
F
F
N
S
-
A
-
D
S
F
A
M
I
R
G
G
-----------
H
I
D
L
A
I
L
G
G
M
E
V
S
Q
N
G
D
L
A
N
W
---
M
I
P
K
----------------------
K
L
I
K
G
MGG
A
M
-------
D
L
-
V
-
H
G
-
A
K
K
V
I
V
I
M
-
E
H
C
N
KYGESK
V
K
K
E
C
S
L
P
L
T
G
K
G
V
V
H
Q
L
I
T
-----------------
D
L
A
V
F
E
-----------------
66
HHSearch
68.35
12%
-83
- C3 -
2W48
3
SORC_KLEPN
A:
[6-313]
--
D
I
R
L
I
V
K
I
A
Q
L
Y
Y
E
Q
-----------
D
M
T
Q
A
Q
I
A
R
E
L
G
I
Y
R
T
T
I
S
R
L
L
K
R
G
R
E
Q
G
I
-
V
T
I
A
I
NYD
Y
N
E
N
L
W
L
-
E
Q
Q
L
K
Q
K
F
G
L
K
E
A
V
V
A
S
S
---
E
E
E
Q
L
S
A
M
G
Q
H
G
A
L
-
L
V
D
R
L
L
E
P
G
D
-----
I
I
G
F
-
S
W
-
G
R
A
V
---
R
S
L
V
E
N
L
P
-
Q
RSQ---
S
--------
R
Q
V
I
C
-
V
P
I
I
------
G
GPSGKLESRYH
V
N
T
L
T
-
Y
G
A
--
A
A
R
L
K
-
A
E
S
H
------
L
A
D
F
P
A
L
L
---
D
N
-
P
L
I
R
N
G
I
M
Q
-
S
Q
H
F
K
T
I
S
S
Y
W
D
----------
S
L
D
V
A
L
V
G
I
G
S
P
A
I
R
D
G
A
N
W
H
AFY
G
S
E
E
S
D
D
L
N
A
R
HVAGDICS
R
F
Y
D
ING
G
L
V
D
TNMS-
E
KTLSIEM
A
K
-
L
-
R
Q
-
A
R
Y
S
I
G
I
A
M
G
E
E
K
------
Y
S
--
G
I
L
G
A
L
H
G
R
Y
I
N
C
L
V
T
-----------------
N
R
E
T
A
E
L
L
---------------
20
PsiBlast_PDB
66.97
23%
-54
- C2 -
1STZ
-
HRCA_THEMA
A:
[17-165]
----
D
R
Q
R
K
V
L
Y
C
I
V
R
E
Y
I
E
NK
K
P
V
S
--
S
Q
R
V
L
E
V
S
N
I
-
E
F
S
S
A
T
I
R
N
D
M
K
K
L
E
Y
L
G
Y
-
I
Y
Q
P
----
H
T
S
A
G
R
I
P
T
D
K
--
G
L
R
F
Y
Y
-----
E
E
M
L
K
I
S
K
E
----
T
S
E
A
D
L
-
A
----
V
E
T
F
K
-----
S
M
P
L
-
A
D
-
P
E
K
V
---
L
F
L
A
G
N
L
--------------------
L
A
R
-
L
T
E
G
--------------------
Y
V
L
-
I
E
R
--
P
N
T
R
D
-
L
K
I
L
------
R
--
V
M
L
I
P
---
V
S
-
E
-
D
-
Y
L
I
F
S
-
I
-
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
HHSearch
62.53
18%
-84
- C3 -
1LK5
2
RPIA_PYRHO
A:
[3-130]
------------------------------------------------------------------------------------------------
V
E
E
M
K
K
I
A
A
K
E
A
L
K
-
F
----
I
E
D
D
M
-----
V
I
G
L
-
G
T
-
G
S
T
T
---
A
Y
F
I
K
L
L
G
-
E
------
K
L
K
R
GEI--
S
D
I
V
G
-
V
P
T
S
------
Y
-------------
Q
A
K
-
L
L
A
--
I
E
-
H
D
-
I
P
I
A
------
S
--
L
D
Q
V
---------------------------
D
-----------
A
I
D
V
A
V
D
G
A
D
E
V
D
P
N
L
N
L
I
K
----
G
R
G
A
----------------------
A
L
T
M
E
----
K
-------
I
I
-
E
-
Y
R
-
A
G
T
F
I
V
L
V
-
D
E
R
K
------
L
V
D
Y
L
-------------------------------------------------------
2
PsiBlast_PDB
62.39
40%
-56
- C2 -
2E1C
2
REG6_PYRHO
A:
[27-73]
----
E
I
D
K
K
I
I
K
I
L
Q
N
D
--------
G
--
K
A
P
L
R
E
I
S
K
I
T
G
L
A
E
S
T
I
H
E
R
I
R
K
L
R
E
S
G
V
-
I
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
79
Fugue
60.96
13%
-49
- C2 -
3ISP
-
Y1985_MYCTU
A:
[5-296]
Q
L
D
G
P
Q
L
A
A
L
A
A
V
V
E
L
G
--------
S
-----
F
D
A
A
A
E
R
L
H
V
T
P
S
A
V
S
Q
R
I
K
S
L
E
Q
Q
V
-----------
G
Q
V
L
V
V
R
E
K
P
C
-
R
A
T
T
A
G
-----
I
P
L
L
R
L
A
A
Q
T
A
L
L
E
S
E
A
L
A
-
E
----
M
G
A
S
L
K
R
T
R
I
T
I
A
V
-
N
A
-
D
S
M
A
TWF
S
A
V
F
D
G
L
G
-
D
------
V
--------
L
L
D
V
R
-
I
E
D
Q
------
D
-------------
H
S
A
-
R
L
L
--
R
E
G
V
A
-
M
G
A
V
TTERNP
V
--
P
G
C
R
V
---
H
P
L
G
-
E
-
M
R
Y
L
P
-
V
-
A
S
R
P
F
V
Q
R
H
LSDGFT
A
A
A
A
A
K
A
P
S
L
A
W
N
R
D
D
G
L
Q
D
M
L
V
R
K
A
---
F
R
R
A
----------------------
I
T
R
P
-----
T
-------
H
F
-
V
-
P
T
-
T
E
G
F
T
A
A
A
-
R
A
G
L
G
-----
W
G
M
F
P
E
K
L
A
A
S
P
L
A
D
G
S
F
V
R
VCD
I
H
L
D
V
P
L
Y
W
Q
C
WKL
D
S
P
I
I
A
R
I
T
D
T
V
R
A
A
A
S
G
L
Y
R
G
Q
64
HHSearch
60.94
20%
-83
- C3 -
1VB5
-
EI2BL_PYRHO
A:
[91-228]
-----------------------------------------------------------------------------------------------
R
M
E
E
A
K
R
E
L
A
S
I
G
A
Q
-
L
----
I
D
D
G
D
-----
V
I
I
T
H
S
F
-
S
S
T
V
---
L
E
I
I
R
T
A
K
E
R
------
K
--------
K
R
F
K
V
I
L
T
E
S
------
S
PDY
E
G
L
-------
H
L
A
-
R
E
L
--
E
F
-
S
G
-
I
E
F
E
------
V
--
I
T
-------------------
D
-
A
Q
M
G
L
F
C
R
------------
E
A
S
I
A
I
V
G
A
D
M
I
T
K
D
-
G
Y
V
V
N
---
K
A
G
T
----------------------
Y
L
L
A
-----
L
-------
A
C
-
H
-
E
N
-
A
I
P
F
Y
V
A
A
-
E
T
Y
K
------
F
H
P
T
L
K
------------------------------------------------------
3
PsiBlast_PDB
59.96
40%
-65
- C2 -
2ZNY
-
REG6_PYRHO
A:
[27-73]
----
E
I
D
K
K
I
I
K
I
L
Q
N
D
--------
G
--
K
A
P
L
R
E
I
S
K
I
T
G
L
A
E
S
T
I
H
E
R
I
R
K
L
R
E
S
G
V
-
I
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
HHSearch
59.53
16%
-76
- C3 -
1M0S
1
RPIA_HAEIN
A:
[3-127]
------------------------------------------------------------------------------------------------
Q
L
E
M
K
K
L
A
A
Q
A
A
L
Q
-
Y
----
V
K
A
D
R
-----
I
V
G
V
-
G
S
-
G
S
T
V
---
N
C
F
I
E
A
L
G
-
T
I
-----
K
D-------
K
I
Q
G
A
-
V
A
A
S
------
K
-------------
E
S
E
-
E
L
L
--
R
K
-
Q
G
-
I
E
V
F
------
N
--
A
N
D
---------------------------
V
S
-----------
S
L
D
I
Y
V
D
G
A
D
E
I
N
P
Q
K
M
M
I
-
K
---
G
G
G
A
----------------------
A
L
T
R
E
----
K
-------
I
V
-
A
-
A
L
-
A
K
K
F
I
C
I
V
-
D
S
S
K
------
Q
V
D
V
L
G
------------------------------------------------------
1
PsiBlast_PDB
59.24
40%
-61
- C2 -
1RI7
-
REG6_PYRHO
A:
[27-73]
----
E
I
D
K
K
I
I
K
I
L
Q
N
D
--------
G
--
K
A
P
L
R
E
I
S
K
I
T
G
L
A
E
S
T
I
H
E
R
I
R
K
L
R
E
S
G
V
-
I
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
65
HHSearch
59.05
20%
-80
- C3 -
3ECS
4
EI2BA_HUMAN
A:
[103-253]
-----------------------------------------------------------------------------------------------
R
I
S
L
S
R
N
K
I
A
D
L
C
H
T
-
F
----
I
K
D
G
A
-----
T
I
L
T
-
H
A
Y
S
R
V
V
---
L
R
V
L
E
A
A
V
A
A
------
K
--------
K
R
F
S
V
Y
V
T
E
S
QPDL
S
G
K
-------------
K
M
A
-
K
A
L
--
C
H
-
L
N
-
V
P
V
T
------
V
--
V
L
-------------------
D
-
A
A
V
G
Y
I
M
E
------------
K
A
D
L
V
I
V
G
A
E
G
V
V
E
N
-
G
G
I
I
N
---
K
I
G
T
----------------------
N
Q
M
A
-----
V
-------
C
A
-
K
-
A
Q
-
N
K
P
F
Y
V
V
A
-
E
S
F
K
------
F
V
R
L
F
P
------------------------------------------------------
71
HHSearch
58.93
22%
-53
- C2 -
3WG9
1
?
A:
[14-157]
--
R
L
P
R
Y
H
R
Y
L
E
E
L
L
K
N
--------
D
VK
R
I
S
S
R
E
L
S
E
K
M
G
V
T
A
S
Q
I
R
Q
D
L
N
N
F
G
--------
G
----
Y
G
Y
N
V
E
E
-------------------------
L
Y
N
N
L
T
-
K
I
L
G
-
L
----
D
K
T
Y
N
-----
T
I
I
I
-
G
A
-
G
N
L
G
---
Q
A
I
A
N
Y
T
S
-
F
---------------
E
------
K
S
G
------
F
-------------
N
L
K
-
G
I
F
--
D
I
N
P
R
L
F
G
L
K
------
I
--
R
D
V
E
V
-------------
M
D
V
E
-
T
V
E
D
F
I
A
R
N
-----------
K
I
D
I
G
I
L
C
I
P
K
D
----------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
58.71
40%
-63
- C2 -
2CYY
-
REG6_PYRHO
A:
[7-53]
----
E
I
D
K
K
I
I
K
I
L
Q
N
D
--------
G
--
K
A
P
L
R
E
I
S
K
I
T
G
L
A
E
S
T
I
H
E
R
I
R
K
L
R
E
S
G
V
-
I
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
58.24
35%
-101
- C2 -
2IA0
-
REG4_PYRFU
A:
[22-65]
---------
I
L
R
L
L
K
K
D
--------
A
--
R
L
T
I
S
E
L
S
E
Q
L
K
K
P
E
S
T
I
H
F
R
I
K
K
L
Q
E
R
G
V
-
I
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.22
40%
-65
- C2 -
2ZNZ
-
REG6_PYRHO
A:
[27-73]
----
E
I
D
K
K
I
I
K
I
L
Q
N
D
--------
G
--
K
A
P
L
R
E
I
S
K
I
T
G
L
A
E
S
T
I
H
E
R
I
R
K
L
R
E
S
G
V
-
I
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
HHSearch
57.93
16%
-73
* C3 *
1XTZ
-
RPIA_YEAST
A:
[19-150]
-------------------------------------------------------------------------------------------------
E
D
A
K
R
A
A
A
Y
R
A
V
D
E
N
LK--
F
D
D
H
K
-----
I
I
G
I
-
G
S
-
G
S
T
V
---
V
Y
V
A
E
R
I
G
-
Q
Y
L
----
H
DPKF
Y
E
V
A
S
K
F
I
C
-
I
P
T
G
------
F
-------------
Q
S
R
-
N
L
I
--
L
D
-
N
K
-
L
Q
L
G
------
S
--
I
E
Q
---------------------------
Y
P
-----------
R
I
D
I
A
F
D
G
A
D
E
V
D
E
N
L
Q
L
I
-
K
---
G
G
G
A
----------------------
C
L
F
Q
-----
E
-------
K
L
V
S
-
T
S
-
A
K
T
F
I
V
V
A
-
D
S
R
K
------
K
S
P
---------------------------------------------------------
82
Fugue
57.89
22%
-75
* C2 *
1BIA
-
?
?:
[1-88]
M
K
D
N
T
V
P
L
K
L
I
A
L
L
A
N
G
--------
E
--
F
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
D
W
G
V
D
V
F
T
V
----
P
G
K
G
Y
S
L
P
E
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
HHSearch
57.87
19%
-67
- C3 -
1UJ6
2
RPIA_THET2
A:
[4-131]
-----------------------------------------------------------------------------------------------
P
L
E
S
Y
K
K
E
A
A
H
A
A
I
A
-
Y
----
V
Q
D
G
M
-----
V
V
G
L
-
G
T
-
G
S
T
A
---
R
Y
A
V
L
E
L
A
-
R
R
L
R
E
GE
L
--------
K
G
V
V
G
-
V
P
T
S
------
R
-------------
A
T
E
-
E
L
A
--
K
R
-
E
G
-
I
P
L
V
------
D
--
L
P
----------------------------
P
E
-----------
G
V
D
L
A
I
D
G
A
D
E
I
A
P
G
L
A
L
I
-
K
---
G
M
G
G
----------------------
A
L
L
R
-----
E
-------
K
I
-
V
E
R
V
-
A
K
E
F
I
V
I
A
-
D
H
T
K
------
K
V
P
V
L
-------------------------------------------------------
56
HHSearch
57.68
16%
-84
- C3 -
3HHE
2
RPIA_BARHE
A:
[23-148]
-----------------------------------------------------------------------------------------------
N
V
Q
Q
L
K
K
M
A
A
L
K
A
L
E
-
F
----
V
E
D
D
M
-----
R
L
G
I
-
G
S
-
G
S
T
V
---
N
E
F
I
P
L
L
G
-
E
R
V
A
N
--
G
--------
L
R
V
T
C
-
V
A
T
S
------
Q
-------------
Y
S
E
-
Q
L
C
--
H
K
-
F
G
-
V
P
I
S
------
T
--
L
E
K
I
---------------------------
P
-----------
E
L
D
L
D
I
D
G
A
D
E
I
G
P
E
M
T
L
I
-
K
---
G
G
G
G
----------------------
A
L
L
H
-----
E
-------
K
I
-
V
-
A
S
A
S
R
A
M
F
V
I
A
-
D
E
T
K
------
M
V
K
T
--------------------------------------------------------
8
PsiBlast_PDB
57.60
33%
-102
- C2 -
2P5V
-
?
A:
[14-64]
--------
K
I
L
Q
V
L
Q
E
N
--------
G
--
R
L
T
N
V
E
L
S
E
R
V
A
L
S
P
S
P
C
L
R
R
L
K
Q
L
E
D
A
G
I
-
V
R
Q
Y
-------
A
A
L
L
S
P
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------