@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0380: (2016-03-15 )
MNKFKILGEYKDWCEIYKDGTLIHNGSSLGIVSQVESELCLRLNYGTNKHFYSILKKCGDFILAVPKKVGFLKAEYKYEPIIFNKQEFDEFIDCIYVDEKLISSIPQLNKEDILNMWFLSNPLHKTYSNEMEMQENIINNILFFSDDEYDISCLKKVINKPDLSVHPIDSNYEVITIYMDGDAGMYEWKGIVIIDNNAYLKIDTHYYIN
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10----.........20.......-.30--..---....-----...40...----------------..-..----.50........-60....-....70---------------.---.----.......80...-----------....-..-90-...-----------.--------.---------------...100---....-...--110.....---------------------..120...-....130......---.140-----------.---........150-..--......160...-...-.170.......180..--.------....-190...----....200.......------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MN
K
F
K
I
LGE
Y
-----
K
D
W
C
E
I
YKD
G
T
L
I
HNGSS-L
G
---
I
V
---
S
Q
V
E
-----
S
E
L
C
L
R
L
N----------------YG-T
N
----
K
H
F
Y
S
I
L
K
K
C
G
-
D
F
I
L
AV-PKKVG----------------
F
---
L
----
K
A
E
Y
KYE
P
-
I
I
F-----------
N
K
Q
E
-
F
D
-
E
F
-
I
D
C
-----------
I
--------Y---------------V
D
E
K
L
I
---
S
SIP-QL
N
--
K
E
D
I
L
N
M
W
---------------------FLSN
P
L
H
K
-TY
S
N
E
M
E
M
Q
E
N
I
I
---NN-------------
I
---
L
F
FSDDEY
D
-
I
-
S
C
--
L
K
K
V
INKPD
L
S
V
-
H
PI-DSN
Y
E
V
I
T
I
Y
MDGDAG--
M
------
Y
E
W
K
-
G
I
V
I
ID----NN
A
Y
L
K
ID
T
H
Y
YIN------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
85.99
13%
-72
* C4 *
1R7M
5
SCE1_YEAST
A:
[3-225]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NIKKNQV
M
N
L
G
P
N
S
K
L
L
-----
K
E
Y
K
S
Q
L
I
E
L
N
I
E
Q
F
E
A
G
-
I
G
---
L
I
L
G
D
A
Y
I
R
S
RDEG
K
T
Y
C
M
Q
F
E
----------------
W
K
-
N
K
----
A
Y
M
D
H
V
C
L
L
Y
D
-
Q
W
V
L
S
P
-
P
H
K
K
E
----------------
R
---
V
N
HLG
N
L
V
I
T
W
G
A
-
Q
T
F
-----------
K
H
Q
A
-
F
N
-
K
L
-
A
N
L
-----------
F
--------
I
---------------
V
N
N
K
K
T
I
P
N
N
L
V
E
-
N
Y
L
--
T
P
M
S
L
A
Y
W
---------------------
F
M
D
D
G
G
K
W
-
D
Y
N
K
N
S
T
N
K
S
I
V
L
---
N
T
-------------
Q
---
S
F
---
T
F
E
E
-
V
-
E
Y
--
L
V
K
G
L
R
N
K
F
Q
L
N
-
C
Y
V
-
K
I
N
K
N
K
P
I
I
Y
I
D
-
S
M
S
--
Y
------
L
I
F
Y
-
N
L
I
--------
K
P
Y
L
I
P
Q
M
M
Y
K
L
P
------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
84.33
15%
-63
- C4 -
1A35
2
TOP1_HUMAN
A:
[41-334]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
W
K
F
L
E
H
K
G
P
V
F
A
P
P
Y
E
P
L
P
E
N
V
K
F
Y
Y
D
G
K
V
-
M
K
---
L
S
---
P
K
A
E
------
E
V
A
T
F
F
A
----------------
K
M
-
L
D
----
H
E
Y
T
T
K
E
I
F
R
K
-
N
F
F
K
D
W
-
R
K
E
M
T
----------------
N
---
E
----
E
K
N
-------
I
I
-----------
T
N
L
S
-
K
C
-
D
F
-
T
Q
M
-----------
S
--------
Q
---------------
Y
F
K
A
Q
T
---
E
A
R
K
-
Q
M
S
--
K
E
E
K
L
K
I
K
---------------------
E
E
N
E
K
L
L
K
-
E
Y
G
--
F
C
I
M
D
N
H
K
---
E
R
-------------
I
---
A
N
F
K
I
E
P
P
G
-
L
-
F
R
--
G
R
G
N
H
P
K
M
G
M
L
K
-
R
R
I
---
M
P
E
D
I
I
I
N
C
S
K
D
A
K
--
V
PSPPPG
H
K
W
K
-
E
V
R
H
D
N
----
K
V
T
W
L
V
S
W
T
E
N
I
Q
G
S
I
K
Y
I
M
L
N
P---------------------------------------------------------------------------------------------------------------------------------
21
Fugue
82.72
11%
-61
- C3 -
1JJ2
-
RL4_HALMA
C:
[1-246]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
A
T
I
Y
D
L
D
G
-----
N
T
D
G
E
V
D
L
P
D
V
F
E
T
P
V
R
S
-
D
L
---
I
G
---
K
A
V
R
-----
A
A
Q
A
N
R
K
Q
D
Y
G
S
DEYAGLRTPAES
F
G
-
S
G
----
R
G
Q
A
H
V
P
K
L
D
G
-
R
A
R
R
V
P
-
Q
A
V
K
G
RSAHPPKTEKDR
S
L
D
L
N
---
D
----
K
E
R
Q
L
A
V
R
-
S
A
L
-----------
A
A
T
A
-
D
A
-
D
L
-
V
A
D
R
G
H
E
F
DRDEVP
V
--------
V
---------------
V
S
D
D
F
E
---
D
L
V
K
-
T
Q
E
--
V
V
S
L
L
E
A
L
---------------------
D
V
H
A
D
I
D
R
-
A
D
E
T
K
I
K
A
G
Q
G
S
A
---
R
G
RK
Y
R
R
P
A
S
-----
I
---
L
F
V
T
S
D
E
P
S
-
T
-
A
A
--
R
----
N
L
A
G
A
D
V
-
A
T
A
-
S
-
E
V
N
T
E
D
L
A
P
G
G
A
P
G
--------------
R
L
T
V
F
T
----
E
S
A
L
A
E
V
A
E
R
----------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
74.95
16%
-58
- C1 -
4WW4
1
?
A:
[3-458]
-----------------------------------------------------------------------------------------------------------------------------------------------QISE
V
R
G
N
T
RDHRTAAHTHIKGLGLNSSGIAEKQAAGFVGQ
C
A
A
R
E
A
C
G
V
V
V
D
L
I
K
A
HKMAG
R
G
V
L
L
A
G
G
P
GTG
K
T
A
L
A
L
A
I
S
Q
E
L
G
T
K
-----
I
P
F
C
P
I
T
--
G
S
E
I
Y
S
--------------
T
E
V
K
-----
K
T
E
V
L
M
E
N
----------------
F
R
-
R
A
----
I
G
L
R
V
R
E
T
K
D
V
-
Y
E
G
E
V
S
-
T
L
L
I
G
----------------
L
---
K
----
S
A
R
G
Q
K
-----
L
-----------
D
Q
K
E
-
R
V
-
Q
V
-
G
D
V
-----------
I
--------
Y
---------------
I
E
T
N
T
G
---
A
C
R
S
-
D
A
Y
--
A
T
E
F
D
L
E
A
---------------------
E
E
Y
V
P
I
P
K
G
E
V
H
K
K
K
E
I
V
Q
D
V
T
---
L
H
-------------
D
---
L
D
V
A
N
A
R
P
D
-
I
-
I
S
--
M
M
G
Q
L
M
K
P
K
M
T
E
-
I
T
D
-
K
L
R
M
E
I
N
K
V
V
Q
K
Y
I
N
Q
GV
A
------
E
L
I
P
-
G
V
L
F
I
D
----
E
A
H
M
L
D
I
E
C
F
T
Y
L
N
K
A
L
E
SPIA
P
I
V
V
L
A
S
NRGIATIRGADDLKAAHGIP
P
D
F
L
Q
R
LL
I
I
P
T
H
P
Y
E
P
D
E
I
R
R
I
V
R
I
R
A
Q
T
E
G
V
Q
L
T
D
A
A
V
D
R
V
A
E
H
G
V
R
I
S
L
R
Y
C
L
Q
L
L
A
P
A
S
I
L
A
R
V
N
GRTQVD
V
Q
D
I
A
E
A
E
E
L
F
LD
A
R
R
S
A
N
I
L
T
S
TGGLH
19
Fugue
70.65
11%
-48
- C3 -
1DCQ
1
A:
[3-278]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L
T
K
E
I
I
S
E
V
Q
R
M
-----
T
G
N
D
V
C
C
D
C
G
A
P
D
P
T
W
L
S
-
T
N
LG
I
L
T
---
C
I
E
C
-----
S
G
I
H
R
E
L
G
----------------
V
H
-
Y
S
----
R
M
Q
S
L
T
L
D
V
L
G
-
T
S
E
L
L
L
-
A
K
N
I
G
----------------
N
---
A
----
G
F
N
E
I
M
E
C
-
C
L
P
SEDPVKPNPGS
D
M
I
A
-
R
K
-
D
Y
-
I
T
A
-----------
K
--------
Y
MERRYARKKHAD
T
A
A
K
L
H
S
L
C
---
E
A
V
K
-
T
R
D
--
I
F
G
L
L
Q
A
Y
A
D
GVDLTEKIPLANGHEPDET
A
L
H
L
A
V
R
S
-
V
D
R
T
S
L
H
I
V
D
F
L
V
---
Q
N
SGNLDKQTGKGST
A
---
L
H
Y
C
C
L
T
D
N
-
A
-
E
C
--
L
K
L
L
L
R
G
K
A
S
I
E
-
I
A
N
-
E
S
G
E
T
P
L
D
I
A
K
R
L
--
K
--
H
------
E
H
C
E
-
E
L
L
T
Q
A
L
S
GR
F
N
S
H
V
H
V
E
Y
E
W
R
L
L
------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
68.47
19%
-57
* C3 *
1JR5
-
ASIA_BPT4
A:
[1-90]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
K
N
I
-
D
T
V
R
E
I
-
I
T
V
A
S
----------------
I
---
L
----
I
K
-
F
S
R
E
D
-
I
V
E
-----------
N
R
A
N
-
F
I
-
A
F
-
L
N
E
-----------
I
GVTHEGRK
L
---------------
N
Q
N
S
F
R
---
K
I
V
S
-
E
L
T
--
Q
E
D
K
K
T
L
I
---------------------
D
E
F
N
E
G
F
E
-
G
V
Y
R
Y
L
E
M
Y
T
N
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
66.45
17%
31
- C3 -
4OWT
-
INT3_HUMAN
A:
[1-466]
GGRL
L
L
S
T
SLDAKD
E
L
E
E
R
L
E
R
C
M
S
I
V
T
S
M
T
AGVS
E
R
E
A
N
D
A
L
N
A
Y
V
C
KG
L
P
Q
H
E
E
I
C
L
G
L
F
T
L
I
L
T
E
PAQ
A
Q
K
C
Y
R
D
L
A
L
V
SRDGM
N
I
V
L
N
K
I
N
Q
I
L
M
EKYLKLQ
D
T
C
R
T
Q
L
V
W
L
V
R
E
L
V
K
S
GVLG
A
D
G
V
C
M
T
F
M
K
Q
IAGGDVT
A
K
N
I
W
L
A
E
S
V
L
D
I
L
T
E
Q
R
E
W
V
L
K
S
S
I
L
I
A
M
A
V
Y
T
Y
L
R
L
I
V
D
HHGT
A
Q
L
Q
A
L
R
Q
K
E
V
D
F
C
I
S
L
L
R
E
R
F
M
E
C
L
MIG
R
D
L
V
R
L
L
Q
N
V
A
R
I
-----
P
E
F
E
L
L
W
K
D
--
I
I
H
N
P
Q
A
-
L
---------
S
P
Q
F
-----
T
G
I
L
Q
L
L
Q
----------------
S
R
-
T
S
----
R
K
F
L
A
C
R
L
T
P
D
M
E
T
K
L
L
F
M
T
S
R
V
R
----------------
F
GQQ
K
----
R
Y
Q
D
W
F
Q
R
-
Q
Y
L
-----------
S
T
P
D
-
S
Q
-
S
L
R
C
D
L
-----------
I
--------
R
---------------
Y
I
C
G
V
V
---
H
P
S
N
-
E
V
L
--
S
S
D
I
L
P
R
W
---------------------
A
I
I
G
W
L
L
T
-
T
C
T
S
N
V
A
A
S
N
A
K
L
---
A
L
-------------
F
Y
DW
L
F
F
S
P
D
K
D
S
-
I
M
N
I
--------
E
P
A
I
L
V
M
H
H
S
M
K
P
H
P
A
I
T
A
T
L
L
D
----------------
F
M
C
R
I
I
P
N
----
F
Y
P
P
L
E
G
H
V
R
Q
G
V
F
S
S
L
N
H
I
V
E
K
RVLAHL
A
P
L
F
D
NPKLD
K
E
L
R
A
M
L
R
E
K
FPEFCS-------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
60.07
39%
27
- C5 -
4J2V
5
ALBU_HORSE
A:
[147-189]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
Y
G
P
E
L
L
F
-----------
H
A
E
E
-
Y
K
A
D
F
-
T
E
C
-----------
C
--------
P
---------------
A
D
D
K
L
A
---
C
L
I
P
-
K
L
D
A
L
K
E
R
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
59.80
15%
-75
- C5 -
3ER9
3
PAP1_VACCW
B:
[173-270]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
Y
L
R
R
-
H
N
K
S
C
I
C
Y
G
S
Y
S
L
Y
---
L
I
---------------
N
P
N
I
R
----------------
Y
G
-
D
I
D
I
L
Q
T
N
S
R
T
F
L
I
D
L
A
-
F
L
I
K
F
I
-
T
G
N
N
I
----------------
I
---
L
----
S
K
I
P
Y
L
R
N
-
Y
M
V
-----------
I
K
D
E
N
D
N
-
H
I
-
I
D
S
-----------
F
--------
N
---------------
I
R
Q
D
T
M
---
N
V
V
P
-
K
I
F
--
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
59.28
39%
27
- C5 -
4OT2
1
ALBU_HORSE
A:
[147-189]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
Y
G
P
E
L
L
F
-----------
H
A
E
E
-
Y
K
A
D
F
-
T
E
C
-----------
C
--------
P
---------------
A
D
D
K
L
A
---
C
L
I
P
-
K
L
D
A
L
K
E
R
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
58.72
39%
34
- C5 -
4F5U
2
ALBU_HORSE
A:
[147-189]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
Y
G
P
E
L
L
F
-----------
H
A
E
E
-
Y
K
A
D
F
-
T
E
C
-----------
C
--------
P
---------------
A
D
D
K
L
A
---
C
L
I
P
-
K
L
D
A
L
K
E
R
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
55.55
39%
19
- C5 -
4F5T
5
ALBU_HORSE
A:
[147-189]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
Y
G
P
E
L
L
F
-----------
H
A
E
E
-
Y
K
A
D
F
-
T
E
C
-----------
C
--------
P
---------------
A
D
D
K
L
A
---
C
L
I
P
-
K
L
D
A
L
K
E
R
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
55.35
39%
10
- C5 -
3V08
7
ALBU_HORSE
A:
[147-189]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
Y
G
P
E
L
L
F
-----------
H
A
E
E
-
Y
K
A
D
F
-
T
E
C
-----------
C
--------
P
---------------
A
D
D
K
L
A
---
C
L
I
P
-
K
L
D
A
L
K
E
R
I
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
54.53
19%
-72
- C5 -
2LMD
-
A:
[20-83]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
H
L
K
K
A
K
-
L
M
F
F
Y
T
-
R
Y
P
S
S
----------------
N
---
M
----
L
K
T
Y
-
F
S
D
-
V
K
F
-----------
N
R
C
I
-
T
S
-
Q
----------------------------------------------------------------
L
I
K
W
---------------------
F
--
S
N
F
R
E
F
Y
Y
I
Q
M
E
K
Y
A
R
Q
A
I
---
N
D
-------------
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
41.44
8%
-37
- C2 -
1USU
1
A:
[174-228]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
---------------------
Y
N
S
T
K
S
V
D
-
E
L
T
S
L
T
D
Y
V
T
R
M
P
EHQ
K
N
-------------
I
---
Y
Y
I
T
G
E
S
L
K
S
V
-
E
K
SP
F
L
D
A
L
K
A
K
N
F
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
36.56
13%
23
- C6 -
2EQK
-
A:
[35-83]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
Q
W
R
R
G
Q
I
-
I
R
---
M
V
---
T
-
D
T
-----
L
V
E
V
L
L
Y
D
----------------
V
G
-
V
E
L
---
V
V
N
V
D
C
L
R
K
L
E
-
E
N
L
K
T
M
-
G
R
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
36.47
19%
118
- C5 -
1D0Q
-
DNAG_GEOSE
A:
[4-25]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
---------------
I
P
E
E
T
I
---
E
A
I
R
R
G
V
D
--
I
V
D
V
I
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
35.33
7%
25
* C6 *
2EQU
-
P20L1_HUMAN
A:
[99-146]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
C
R
Y
Y
P
A
K
I
-
E
A
---
I
N
---
K
E
G
-------
T
F
T
V
Q
F
-----------------
Y
D
G
V
I
R
---
C
L
K
R
M
H
I
K
A
M
P
-
E
D
A
K
G
Q
-
D
W
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
21.70
29%
225
- C5 -
2ROD
-
APR_MOUSE
B:
[24-37]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
Q
L
R
K
I
G
-
D
K
V
Y
C
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
20.57
23%
104
* C5 *
3J1R
-
?
A:
[8-33]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
S
P
V
-
I
A
T
L
L
L
I
L
I
A
V
A
A
A
V
L
--
L
------
Y
T
W
V
-
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------