@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0434: (2016-03-15 )
VKEKHNPRRKYCLISGLAIIFSLWIIIGNGAKVQAETITVPTPIKQIFSDDAFAETIKDNLKKKSVTDAVTQNELNSIDQIIANNSDIKSVQGIQYLPNVTKLFLNGNKLTDIKPLANLKNLGWLFLDENKVKDLSSLKDLKKLKSLSLEHNGISDINGLVHLPQLESLYLGNNKITDITVLSRLTKLDTLSLEDNQISDIVPLAGLTKLQNLYLSKNHISDLRALAGLKNLDVLELFSQECLNKPINHQSNLVVPNTVKNTDGSLVTPEIISDDGDYEKPNVKWHLPEFTNEVSFIFYQPVTIGKAKARFHGRVTQPLKEVYTVSYDVDGTVIKTKVEAGTRITAPKPPTKQGYVFKGWYTEKNGGHEWNFNTDYMSGNDFTLYAVFKAETTEKAVNLTRYVKYIRGNAGIYKLPREDNSLKQGTLASHRCKALTVDREARNGGKLWYRLKNIGWTKAENLSLDRYDKMEYDKGVTAYARVRNASGNSVWTKPYNTAGAKHVNKLSVYQGKNMRILREAKTPITTWYQFSIGGKVIGWVDTRALNTFYKQSMEKPTRLTRYVSANKAGESYYKVPVADNPVKRGTLAKYKNQKLIVDCQATIEGQLWYRIRTSSTFIGWTKAANLRAQK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........----------------------100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
VKEKHNPRRK
Y
C
L
I
S
G
L
A
I
I
F
S
L
W
I
IIGNG
A
K
V
Q
A
E
T
I
TVP
T
P
I
K
Q
I
FS
D
D
A
F
A
E
T
I
K
D
N
L
K
KKSV
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
IANNSDIKSVQG
I
Q
YL
P
N
----------------------
V
T
K
L
FLNGNKLTD
I
K
P
L
ANLKN
L
G
W
L
F
LDENK
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
SLEHNGISDINGLVHLP
Q
L
E
S
L
YLGNNKI
T
D
I
T
V
L
S
R
L
TKL
D
T
L
SLEDNQISDIVPL
A
G
L
T
K
L
Q
N
L
YLSK
N
H
I
S
D
L
R
A
L
AGLKN
L
D
V
L
E
L
F
S
Q
E
C
LNKPINHQSNLVVPNTVKNTDG
S
L
V
T
P
E
IISDDGDYEKP
N
V
K
W
HL
P
E
FTNE
V
S
F
I
F
YQPVTIG
K
A
K
A
R
FHGR
V
T
Q
P
L
K
E
V
Y
T
V
S
YDVDG
T
V
I
K
T
K
VEAG
T
R
ITAPKPPTKQ
G
Y
V
F
K
G
W
Y
TEKNGGHEWNFNTDYMSGN
D
F
T
L
Y
A
V
F
KAET
T
E
K
A
V
N
L
T
R
Y
V
K
Y
I
RGNA
G
I
Y
KLPREDNSLKQGTLASHR
C
K
A
L
T
VDREARNG
G
K
L
W
Y
R
LKNIGWTKAENLSLDRY
D
K
M
E
YDKGV
T
A
Y
A
R
V
RNASGN
S
V
W
TKPYNTAGAKH
V
N
K
L
S
VYQGKN
M
R
I
L
REAKTP
I
T
T
W
Y
Q
F
SIG
G
K
V
I
G
W
V
D
T
R
A
L
N
T
F
Y
K
Q
S
MEK
P
T
R
L
T
R
YVSANKAGE
S
Y
Y
KVPVADNPVKRG
T
L
A
KYKN
Q
K
L
I
V
D
C
Q
A
T
IE
G
Q
L
W
Y
R
I
RTSS
T
F
I
G
W
TKAANLRAQK
113
Fugue
92.52
99%
-96
* C6 *
1M9S
8
INLB_LISMO
A:
[3-596]
-----------------------------------
E
T
I
T
V
S
T
P
I
K
Q
I
F
P
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
T
N
L
K
N
L
G
W
L
F
L
D
E
N
K
I
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
-----------------------------------------------------------------------
E
T
T
E
K
T
V
N
L
T
R
Y
V
K
Y
I
R
G
N
A
G
I
Y
K
L
P
R
E
D
N
S
L
K
Q
G
T
L
A
S
H
R
C
K
A
L
T
V
D
R
E
A
R
N
G
G
K
L
W
Y
R
L
K
N
I
G
W
T
K
A
E
N
L
S
L
D
R
Y
D
K
M
E
Y
D
K
G
V
T
A
Y
A
R
V
R
N
A
S
G
N
S
V
W
T
K
P
Y
N
T
A
G
A
K
H
V
N
K
L
S
V
Y
Q
G
K
N
M
R
I
L
R
E
A
K
T
P
I
T
T
W
Y
Q
F
S
I
G
G
K
V
I
G
W
V
D
T
R
A
L
N
T
F
Y
K
Q
S
M
E
K
P
T
R
L
T
R
Y
V
S
A
N
K
A
G
E
S
Y
Y
K
V
P
V
A
D
N
P
V
K
R
G
T
L
A
K
Y
K
N
Q
K
L
I
V
D
C
Q
A
T
I
E
G
Q
L
W
Y
R
I
R
T
S
S
T
F
I
G
W
T
K
A
A
N
L
R
A
Q
-
93
HHSearch
92.45
99%
-96
- C5 -
1M9S
8
INLB_LISMO
A:
[3-596]
-----------------------------------
E
T
I
T
V
S
T
P
I
K
Q
I
F
P
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
T
N
L
K
N
L
G
W
L
F
L
D
E
N
K
I
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
-----------------------------------------------------------------------
E
T
T
E
K
T
V
N
L
T
R
Y
V
K
Y
I
R
G
N
A
G
I
Y
K
L
P
R
E
D
N
S
L
K
Q
G
T
L
A
S
H
R
C
K
A
L
T
V
D
R
E
A
R
N
G
G
K
L
W
Y
R
L
K
N
I
G
W
T
K
A
E
N
L
S
L
D
R
Y
D
K
M
E
Y
D
K
G
V
T
A
Y
A
R
V
R
N
A
S
G
N
S
V
W
T
K
P
Y
N
T
A
G
A
K
H
V
N
K
L
S
V
Y
Q
G
K
N
M
R
I
L
R
E
A
K
T
P
I
T
T
W
Y
Q
F
S
I
G
G
K
V
I
G
W
V
D
T
R
A
L
N
T
F
Y
K
Q
S
M
E
K
P
T
R
L
T
R
Y
V
S
A
N
K
A
G
E
S
Y
Y
K
V
P
V
A
D
N
P
V
K
R
G
T
L
A
K
Y
K
N
Q
K
L
I
V
D
C
Q
A
T
I
E
G
Q
L
W
Y
R
I
R
T
S
S
T
F
I
G
W
T
K
A
A
N
L
R
A
Q
-
1
PsiBlast_PDB
91.61
98%
-96
- C5 -
1M9S
8
INLB_LISMO
A:
[3-596]
-----------------------------------
E
T
I
T
V
S
T
P
I
K
Q
I
F
P
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
T
N
L
K
N
L
G
W
L
F
L
D
E
N
K
I
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
-----------------------------------------------------------------------
E
T
T
E
K
T
V
N
L
T
R
Y
V
K
Y
I
R
G
N
A
G
I
Y
K
L
P
R
E
D
N
S
L
K
Q
G
T
L
A
S
H
R
C
K
A
L
T
V
D
R
E
A
R
N
G
G
K
L
W
Y
R
L
K
N
I
G
W
T
K
A
E
N
L
S
L
D
R
Y
D
K
M
E
Y
D
K
G
V
T
A
Y
A
R
V
R
N
A
S
G
N
S
V
W
T
K
P
Y
N
T
A
G
A
K
H
V
N
K
L
S
V
Y
Q
G
K
N
M
R
I
L
R
E
A
K
T
P
I
T
T
W
Y
Q
F
S
I
G
G
K
V
I
G
W
V
D
T
R
A
L
N
T
F
Y
K
Q
S
M
E
K
P
T
R
L
T
R
Y
V
S
A
N
K
A
G
E
S
Y
Y
K
V
P
V
A
D
N
P
V
K
R
G
T
L
A
K
Y
K
N
Q
K
L
I
V
D
C
Q
A
T
I
E
G
Q
L
W
Y
R
I
R
T
S
S
T
F
I
G
W
T
K
A
A
N
L
R
A
Q
-
22
PsiBlast_CBE
76.51
100%
-114
- C5 -
2WQU
6
INLB_LISMO
F:
[5-288]
------------------------------------
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
76.22
100%
-112
- C5 -
2WQU
5
INLB_LISMO
E:
[5-288]
------------------------------------
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
76.18
92%
-114
- C5 -
4AW4
9
INLB_LISMO
B:
[4-310]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
LTSLNLSNNQITDISPIQYLPN
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
95
HHSearch
75.87
100%
-114
- C5 -
1H6T
-
INLB_LISMO
A:
[36-320]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
75.73
99%
-114
- C5 -
1H6T
-
INLB_LISMO
A:
[35-321]
----------------------------------
S
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
75.71
92%
-111
- C5 -
4AW4
6
INLB_LISMO
C:
[4-310]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
LTSLNLSNNQITDISPIQYLPN
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
75.67
100%
-115
- C5 -
2WQU
7
INLB_LISMO
A:
[4-288]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
75.34
100%
-110
- C5 -
2WQV
5
INLB_LISMO
B:
[5-288]
------------------------------------
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
114
Fugue
75.09
98%
-111
- C6 -
1H6T
-
INLB_LISMO
A:
[31-321]
------------------------------
G
P
L
G
S
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
74.96
100%
-111
- C5 -
2WQU
6
INLB_LISMO
B:
[4-288]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
-----
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
74.80
100%
-114
- C5 -
2UZX
-
INLB_LISMO
A:
[36-320]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
74.61
98%
-111
- C5 -
2WQW
7
INLB_LISMO
B:
[1-286]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
C
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
C
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
A
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
74.57
98%
-109
- C5 -
2WQX
-
INLB_LISMO
A:
[36-321]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
R
R
I
V
P
L
A
R
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
R
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
A
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.51
99%
-112
- C5 -
2Y5Q
3
INLB_LISMO
A:
[5-291]
----------------------------------
S
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
74.36
100%
-110
- C5 -
2WQV
4
INLB_LISMO
A:
[5-288]
------------------------------------
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
----
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
74.32
92%
-115
- C5 -
4AW4
14
INLB_LISMO
A:
[4-310]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
LTSLNLSNNQITDISPIQYLPN
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
------
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
74.27
98%
-112
- C5 -
2WQW
5
INLB_LISMO
A:
[1-286]
-----------------------------------
E
T
I
T
V
P
T
P
I
K
Q
I
F
S
D
D
A
F
A
E
T
I
K
D
N
L
K
K
K
S
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
L
P
N
----------------------
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
C
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
C
G
L
K
N
L
D
V
L
E
L
F
S
Q
E
A
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------