@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2018: (2016-03-31 )
MATIHFTKVHGSQNDFFLVDEEGNQIMDWSDAKRADFAIKLCDREHSLGGADGILYVTKSSEAGPIGQMRVVNSDGSIASMCGNGLRTVARYLLEKHALTEAKVETMKAILDVKKATSLGFDIPTYQVEISPVKFNAESLPMNVGVEKLFNQVVPELDAELAFSAVSVPNPHLITFVDQTVLDSDRQETLASYLNSENPYFPDGVNVSFVKRLSDDAIYVRTFERGVGFTNACGTAMSACSLIKKMLDKDTFETPLNVYNDGGRVQVTAKKDEAGDISLQLIGNATFVSTGSVSYESDTVTELTNEATPEQAQYQELVKEVKEFLKTTE
Atome Classification :
(21 SA)
.........10........20........30..-......40........50........60.--------------.......-------70.-------.......80........90........---100.---.---.-....--110.......120.....------..130.......140-.....---..150...--..---..160.......170.......-----180.---......--.190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
T
I
H
F
T
K
VHGSQN
D
F
F
L
VDEEG
N
Q
IMDWSDAK-RA
D
F
A
I
K
L
CDREHSLGGAD
G
I
L
Y
V
TKSSE--------------AGPIG
Q
M
-------
R
V
V-------NSDG
S
I
A
S
M
C
G
N
G
L
R
T
V
A
R
Y
L
L
E
K
HA
L
---
T
E
A
K
---
V
---
E
-
T
M
K
A
--
I
L
D
V
K
K
A
TSLGFDI
P
T
Y
Q
------
V
E
I
S
P
V
K
FNAESLPM-NV
G
V
E
---
K
L
F
N
Q
V
V
P
--
E
L
---
D
A
E
L
A
F
S
AVSVPNP
H
L
I
T
F
V
D
Q
-----
T
V-L---D
S
D
R
Q
E
--
T
L
A
S
Y
LNSENPYFPDGV
N
V
S
F
V
K
R
LSDD
A
I
Y
V
R
T
FERGVGFT
N
A
C
G
T
A
M
S
A
C
S
L
I
K
K
M
LDKDTFETPLNVYNDG
G
R
V
Q
V
T
AKKDEAG
D
I
S
L
Q
L
IG
N
A
T
F
V
STGSVSYES
D
T
V
T
E
L
TNEATP
E
Q
A
Q
Y
Q
E
L
V
K
E
V
K
E
F
L
KTTE
28
PsiBlast_CBE
92.26
31%
-75
- C1 -
3EJX
1
DAPF_ARATH
D:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDGQVK
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
VVD
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
1
PsiBlast_PDB
91.86
31%
-75
- C1 -
3EJX
1
DAPF_ARATH
A:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDG
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
3
PsiBlast_PDB
91.71
29%
-97
- C1 -
2OTN
-
DAPF_BACAN
A:
[1-285]
M
S
Q
F
S
F
T
K
M
H
G
L
G
N
S
Y
I
Y
V
N
M
F
E
E
Q
I
---
P
E
E
D
-
L
A
L
V
A
E
K
V
S
N
I
N
T
G
I
G
-
A
D
G
M
I
L
I
C
P
S
D
V
--------------
A
-
P
V
-
K
M
-------
R
M
F
-------
N
N
D
G
S
E
G
K
S
C
G
N
G
L
R
C
V
A
K
Y
A
Y
E
-
H
K
L
---
V
E
D
T
---
V
F
T
I
E
-
T
L
A
G
--
I
V
T
A
E
V
T
V
E
E
G
-
K
V
T
L
A
K
------
I
D
M
G
A
P
R
L
T
R
A
E
I
P
M
L
G
E
G
E
T
---
P
F
I
R
E
N
F
L
--
Y
N
---
N
H
R
Y
A
F
T
A
V
S
M
G
N
P
H
A
V
I
F
V
D
D
--------
V
---
E
Q
A
P
L
T
--
T
L
G
P
V
L
E
T
-
H
E
M
F
P
E
R
V
N
V
E
F
I
E
I
L
N
E
E
E
M
N
F
R
V
W
E
R
G
S
G
V
T
Q
A
C
G
T
G
A
C
A
A
V
V
A
S
I
L
N
G
K
M
E
R
G
K
E
I
T
V
H
L
A
G
G
D
L
M
I
A
W
T
--
E
E
G
N
V
L
M
K
--
G
P
A
E
V
I
C
R
G
V
Y
E
Y
K
---------------------------------
2
PsiBlast_PDB
91.45
31%
-74
- C1 -
3EKM
1
DAPF_ARATH
A:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDG
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
26
PsiBlast_CBE
91.17
31%
-76
- C1 -
3EJX
1
DAPF_ARATH
F:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDGQVK
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
VVD
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
30
PsiBlast_CBE
91.15
31%
-75
- C1 -
3EJX
1
DAPF_ARATH
B:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDG
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
27
PsiBlast_CBE
91.14
31%
-75
- C1 -
3EJX
1
DAPF_ARATH
E:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDGQVK
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
VVD
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
21
PsiBlast_CBE
90.73
31%
-75
- C1 -
3EKM
1
DAPF_ARATH
F:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDGQVK
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
VVD
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
23
PsiBlast_CBE
90.44
31%
-76
- C1 -
3EKM
1
DAPF_ARATH
D:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDGQVK
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
VVD
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
29
PsiBlast_CBE
90.40
31%
-76
- C1 -
3EJX
1
DAPF_ARATH
C:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDGQVK
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
VVD
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
22
PsiBlast_CBE
90.38
31%
-73
- C1 -
3EKM
1
DAPF_ARATH
E:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDGQVK
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
VVD
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
25
PsiBlast_CBE
90.12
31%
-75
- C1 -
3EKM
1
DAPF_ARATH
B:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDG
Q
V
K
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
V
V
D
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
24
PsiBlast_CBE
90.09
31%
-74
- C1 -
3EKM
1
DAPF_ARATH
C:
[25-308]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
-----
D
S
S
E
P
K
I
T
Q
E
Q
A
A
K
L
C
D
R
N
F
G
V
G
-
A
D
G
V
I
F
A
M
P
G
V
N
---------------
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
-----------
A
E
---
L
---
E
-
N
L
Q
G
--
K
H
S
F
T
I
H
T
G
A
G
L
I
V
P
E
I
Q
DDGQVK
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
---
K
G
E
A
V
V
E
A
--
E
L
VVD
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
GGPNL
K
V
-
D
---
D
L
N
L
P
E
--
I
G
P
K
F
E
H
H
E
--
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
--
A
C
A
L
V
V
A
A
V
L
E
G
R
A
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
-------------------------------------
31
HHSearch
87.78
29%
-79
- C1 -
3EJX
1
DAPF_ARATH
A:
[25-311]
-
G
V
L
H
F
V
K
Y
H
G
L
G
N
D
F
I
L
V
D
N
R
D
S
S
E
P
K
I
T
Q
-----
E
Q
A
A
K
L
C
D
R
N
-
F
G
V
G
A
D
G
V
I
F
A
M
P
G
V
---------------
N
G
T
D
Y
A
M
-------
R
I
F
-------
N
S
D
G
S
E
P
E
M
C
G
N
G
V
R
C
F
A
R
F
I
A
E
L
E
N
L
Q
G
K
H
S
F
T
---
I
---
H
-
T
G
A
G
--
L
I
V
P
E
I
Q
D
D
-----
G
Q
V
K
------
V
D
M
G
T
P
I
L
K
A
Q
D
V
P
T
-
K
L
S
G
N
KGE
A
V
V
E
A
-
E
L
--
V
V
D--
G
V
S
W
N
V
T
C
V
S
M
G
N
P
H
C
I
T
F
G
K
K
-----
G
G
P
N
LKV
D
D
L
N
L
P
--
E
I
G
P
K
F
E
-
H
H
E
M
F
P
A
R
T
N
T
E
F
V
E
V
L
S
R
S
H
L
K
M
R
V
W
E
R
G
A
G
A
T
L
A
C
G
T
G
A
C
A
L
V
V
A
A
V
L
E
G
R
A
--
D
R
K
C
T
V
D
L
P
G
G
P
L
E
I
E
W
K
Q
E
---
D
N
H
I
Y
M
T
G
P
A
E
A
V
F
Y
G
S
A
L
L
----------------------------------
34
HHSearch
86.67
28%
-88
* C1 *
2OTN
-
DAPF_BACAN
A:
[2-285]
-
S
Q
F
S
F
T
K
M
H
G
L
G
N
S
Y
I
Y
V
N
M
F
E
E
---
Q
I
P
E
E
D
-
L
A
L
V
A
E
K
V
S
N
I
N
-
T
G
I
G
A
D
G
M
I
L
I
C
P
S
D
----------------
V
A
P
V
K
M
-------
R
M
F
-------
N
N
D
G
S
E
G
K
S
C
G
N
G
L
R
C
V
A
K
Y
A
Y
E
H
K
L
V
ED-
T
V
F
T
---
I
---
E
-
T
L
A
G
--
I
V
T
A
E
V
T
V
E
E
-
G
K
V
T
L
A
K
------
I
D
M
G
A
P
R
L
T
R
A
E
I
P
M
-
L
-
G
E
G
---
E
T
P
F
I
R
E
N
F
L
Y
N
---
N
H
R
Y
A
F
T
A
V
S
M
G
N
P
H
A
V
I
F
V
D
D
-----
V
E
-
Q
-----
A
P
L
T
--
T
L
G
P
V
L
E
-
T
H
E
M
F
P
E
R
V
N
V
E
F
I
E
I
L
N
E
E
E
M
N
F
R
V
W
E
R
G
S
G
V
T
Q
A
C
G
T
G
A
C
A
A
V
V
A
S
I
L
N
G
K
M
E
R
G
K
E
I
T
V
H
L
A
G
G
D
L
M
I
A
W
T
E
E
----
G
N
V
L
M
K
G
P
A
E
V
I
C
R
G
V
Y
E
Y
K
---------------------------------
11
PsiBlast_PDB
85.59
27%
-84
- C1 -
2Q9H
3
DAPF_HAEIN
A:
[1-273]
---
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
G
V
T
Q
N
V
F
F
T
P
E
T
I
-
R
-----
R
L
A
N
R
-
H
C
G
I
G
F
D
Q
L
L
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
-------
R
I
F
-------
N
A
D
G
S
E
V
S
Q
S
G
N
G
A
R
C
F
A
R
F
V
T
L
K
-
G
L
---
T
N
K
K
D
I
S
V
---
S
-
T
Q
K
G
N
M
V
L
T
V
K
D
D
N
Q
I
R
V
N
M
G
E
P
I
------
W
E
P
A
K
I
P
F
T
A
N
K
F
E
K
-
N
Y
I
L
R
---
T
D
I
Q
T
V
L
-------------
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
D
D
--------
I
---
Q
T
A
N
V
E
--
Q
L
G
P
L
L
E
S
H
E
-
R
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
--
A
C
A
A
V
A
V
G
I
M
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
--
E
W
N
G
V
G
H
-
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
-----------------------------------
10
PsiBlast_PDB
85.29
28%
-85
- C1 -
2GKJ
3
DAPF_HAEIN
A:
[1-273]
---
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
G
V
T
Q
N
V
F
F
T
P
E
T
I
-
R
-----
R
L
A
N
R
-
H
C
G
I
G
F
D
Q
L
L
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
-------
R
I
F
-------
N
A
D
G
S
E
V
S
Q
C
G
N
G
A
R
C
F
A
R
F
V
T
L
K
-
G
L
---
T
N
K
K
D
I
S
V
---
S
-
T
Q
K
G
N
M
V
L
T
V
K
D
D
N
Q
I
R
V
N
M
G
E
P
I
------
W
E
P
A
K
I
P
F
T
A
N
K
F
E
K
-
N
Y
I
L
R
---
T
D
I
Q
T
V
L
-------------
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
D
D
--------
I
---
Q
T
A
N
V
E
--
Q
L
G
P
L
L
E
S
H
E
-
R
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
--
A
C
A
A
V
A
V
G
I
M
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
--
E
W
N
G
V
G
H
-
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
-----------------------------------
32
HHSearch
84.97
30%
-75
- C1 -
3FVE
3
DAPF_MYCTU
A:
[2-288]
---
M
I
F
A
K
G
H
G
T
Q
N
D
F
V
L
L
P
D
V
D
A
E
-
L
V
L
T
A
-----
A
R
V
A
A
L
C
D
R
R
-
K
G
L
G
A
D
G
V
L
R
V
T
T
A
G
A
A
Q
A
V
GVLDSLPEGV
R
V
T
D
W
Y
M
-------
D
Y
R
-------
N
A
D
G
S
A
A
Q
M
C
G
N
G
V
R
V
F
A
H
Y
L
R
A
S
G
L
E
VR-
D
E
F
V
---
V
---
G
-
S
L
A
G
--
P
R
P
V
T
C
H
H
V
E
A
-
A
Y
A
D
V
S
------
V
D
M
G
K
A
N
R
L
G
A
G
-
E
------------
A
V
--------------
F
H
G
L
A
V
D
V
G
N
P
H
L
A
C
V
D
S
Q
-----
L
T
-
V
---
D
--
G
L
A
AL
D
V
G
--
V
S
F
D
G
A
Q
F
P
D
G
V
N
V
E
V
L
T
A
P
V
D
G
A
V
W
M
R
V
H
E
R
G
V
G
E
T
R
S
C
G
T
G
T
V
A
A
A
V
A
A
L
A
A
V
G
S
P
-
T
G
T
L
T
V
H
V
P
G
G
E
V
V
V
T
V
T
D
-----
A
T
S
F
L
R
G
P
S
V
L
V
A
R
G
D
L
A
D
D
W
W
N
A
-----------------------------
9
PsiBlast_PDB
84.94
28%
-85
- C1 -
2GKE
5
DAPF_HAEIN
A:
[1-273]
---
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
G
V
T
Q
N
V
F
F
T
P
E
T
I
-
R
-----
R
L
A
N
R
-
H
C
G
I
G
F
D
Q
L
L
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
-------
R
I
F
-------
N
A
D
G
S
E
V
S
Q
C
G
N
G
A
R
C
F
A
R
F
V
T
L
K
-
G
L
---
T
N
K
K
D
I
S
V
---
S
-
T
Q
K
G
N
M
V
L
T
V
K
D
D
N
Q
I
R
V
N
M
G
E
P
I
------
W
E
P
A
K
I
P
F
T
A
N
K
F
E
K
-
N
Y
I
L
R
---
T
D
I
Q
T
V
L
-------------
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
D
D
--------
I
---
Q
T
A
N
V
E
--
Q
L
G
P
L
L
E
S
H
E
-
R
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
--
A
C
A
A
V
A
V
G
I
M
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
--
E
W
N
G
V
G
H
-
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
-----------------------------------
8
PsiBlast_PDB
84.59
28%
-83
- C1 -
1GQZ
-
DAPF_HAEIN
A:
[1-273]
---
M
Q
F
S
K
M
H
G
L
G
N
D
F
V
V
V
D
G
V
T
Q
N
V
F
F
T
P
E
T
I
-
R
-----
R
L
A
N
R
-
H
C
G
I
G
F
D
Q
L
L
I
V
E
A
P
Y
D
--------------
P
E
L
D
F
H
Y
-------
R
I
F
-------
N
A
D
G
S
E
V
S
Q
C
G
N
G
A
R
C
F
A
R
F
V
T
L
K
-
G
L
---
T
N
K
K
D
I
S
V
---
S
-
T
Q
K
G
N
M
V
L
T
V
K
D
D
N
Q
I
R
V
N
M
G
E
P
I
------
W
E
P
A
K
I
P
F
T
A
N
K
F
E
K
-
N
Y
I
L
R
---
T
D
I
Q
T
V
L
-------------
C
G
A
V
S
M
G
N
P
H
C
V
V
Q
V
D
D
--------
I
---
Q
T
A
N
V
E
--
Q
L
G
P
L
L
E
S
H
E
-
R
F
P
E
R
V
N
A
G
F
M
Q
I
I
N
K
E
H
I
K
L
R
V
Y
E
R
G
A
G
E
T
Q
A
C
G
S
G
--
A
C
A
A
V
A
V
G
I
M
Q
G
L
L
N
N
N
V
Q
V
D
L
P
G
G
S
L
M
I
--
E
W
N
G
V
G
H
-
P
L
Y
M
T
G
E
A
T
H
I
Y
D
G
F
I
T
-----------------------------------
4
PsiBlast_PDB
66.79
30%
-65
- C1 -
3FVE
3
DAPF_MYCTU
A:
[4-261]
-----
F
A
K
G
H
G
T
Q
N
D
F
V
L
L
P
D
V
D
A
E
L
V
-----
L
-
T
A
A
R
V
A
A
L
C
D
R
R
K
G
L
G
-
A
D
G
V
L
R
V
T
T
A
G
A
--------------
A
Q
A
V
G
V
L
DSLPEGV
R
V
T
DWYMDYR
N
A
D
G
S
A
A
Q
M
C
G
N
G
V
R
V
F
A
H
Y
L
--
R
A
S
G
---
L
E
V
R
---
D
---
E
F
V
V
G
S
--
L
A
G
P
R
P
V
T
C
H
H
V
E
A
A
Y
A
D
------
V
S
V
D
M
G
K
A
N
R
L
G
A
G
E
-
A
V
--------
F
H
G
L
----------------
A
V
D
V
G
N
P
H
L
A
C
V
D
S
Q
-----
L
T
-
V
---
D
G
L
A
A
L
--
D
V
G
--
V
S
F
D
G
A
Q
F
P
D
G
V
N
V
E
V
L
T
A
P
V
D
G
A
V
W
M
R
V
H
E
R
G
V
G
E
T
R
S
C
G
T
G
T
V
A
A
A
V
A
A
L
A
A
V
G
S
P
T
G
T
-
L
T
V
H
V
P
G
G
E
V
V
V
T
-------------------------------------------------------------