@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2215: (2016-04-02 )
MALVEVEHLTGGYTKRPVLKDISFAIEEKQIVGLIGLNGAGKSTTIKHITGLMHPKQGTIKINNHQLVEDTETYRKQFSYIPETPVLYEELTLKEHLELTGMAYGISEEELHARMTPLLKEFRLEKKLNWFPAHFSKGMKQKVMIMSAFLIEPKLYIIDEPFVGLDPLGIQSLLNWMDEMRSKGASILMSTHILATAEKYCDTFIIIHQGEIRAEGTLKDLQTNFEMPGASLDEIYIQLTKEEEADEDDI
Atome Classification :
(20 SA)
-.........10...----.----....20........30........40........50........60....--..----..--------------70---.----..----......80.....-...90......-..100.-..-....110.......120-......-.130.......140.......150.......160.......170.......180-..-......190.......200.......210.......220.......230.......240.......250--------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
A
L
V
E
V
EHLTGGYT----K----R
P
V
L
K
D
I
S
F
A
IEE
K
Q
I
V
G
L
I
GLNGAGKS
T
T
I
K
H
I
T
G
LMHPKQ
G
T
I
K
INN
H
--
Q
L----V
E
--------------
D
----
T
----
E
T
----
Y
R
K
Q
FSYIPETP
V
-
L
Y
E
E
L
T
L
K
E
H
L
-
E
L
T
G
M
A-YG-I
S
E
E
E
L
H
A
R
M
T
P
L
L
K
E
F
-
R
L
E
KKL-NWF
P
A
H
F
SKG
M
K
Q
K
V
M
I
M
S
A
F
L
IE
P
K
L
Y
I
I
DEPFVGLD
P
L
G
I
Q
S
L
L
N
W
M
D
E
M
-
R
-SK-
G
A
S
I
L
M
S
T
H
I
L
A
T
A
E
KYC
D
T
F
I
I
I
HQ
G
E
I
R
AEG
T
L
K
D
L
Q
TNFEMPGA
S
L
D
E
I
Y
I
Q
LTKEEEADEDDI----------------------------------------------------------------------------------------------
1
PsiBlast_PDB
96.42
63%
-128
- C1 -
4RVC
-
?
A:
[2-241]
--
T
L
L
E
V
K
D
L
S
G
G
Y
T
----
A
----
Q
N
V
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
I
S
I
N
G
Y
--
R
L
----
A
D
--------------
G
----
P
----
E
T
----
Y
R
R
Q
F
A
Y
I
P
E
T
P
V
-
L
Y
E
E
L
T
L
E
E
H
L
-
R
L
A
A
M
A
-
Y
G
-
L
S
E
A
E
Y
E
R
R
L
P
P
L
L
R
E
F
-
R
L
E
R
R
L
-
S
S
F
P
A
H
F
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
P
L
A
I
H
A
L
L
E
R
M
N
E
Q
-
K
-
A
K
-
G
A
G
I
L
L
S
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
V
I
L
H
N
G
R
V
K
A
K
G
T
L
D
D
I
R
R
Q
F
G
L
R
G
A
S
L
D
E
L
Y
V
E
L
T
K
-------------------------------------------------------------------------------------------------------
42
HHSearch
75.54
33%
-114
- C1 -
1VPL
2
?
A:
[14-251]
--
G
A
V
V
V
K
D
L
R
K
R
I
G
----
K
----
K
E
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
K
--
N
V
----
V
E
--------------
E
----
P
----
H
E
----
V
R
K
L
I
S
Y
L
P
E
E
A
G
-
A
Y
R
N
M
Q
G
I
E
Y
L
-
R
F
V
A
G
F
-
Y
A
-
S
S
S
S
E
I
E
E
M
V
E
R
A
T
E
I
A
-
G
L
G
E
K
I
-
K
D
R
V
S
T
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
A
-
S
-
Q
E
-
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
E
R
Y
K
--
A
Q
N
I
E
E
V
F
E
E
V
V
K
-------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
75.10
32%
-114
- C1 -
1VPL
2
?
A:
[14-251]
--
G
A
V
V
V
K
D
L
R
K
R
I
G
----
K
----
K
E
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
V
F
G
K
--
N
V
----
V
E
--------------
E
----
P
----
H
E
----
V
R
K
L
I
S
Y
L
P
E
E
A
G
-
A
Y
R
N
M
Q
G
I
E
Y
L
-
R
F
V
A
G
F
-
Y
A
-
S
S
S
S
E
I
E
E
M
V
E
R
A
T
E
I
A
-
G
L
G
E
K
I
-
K
D
R
V
S
T
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
A
-
S
-
Q
E
-
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
E
T
G
T
V
E
E
L
K
E
R
Y
K
--
A
Q
N
I
E
E
V
F
E
E
V
V
K
-------------------------------------------------------------------------------------------------------
47
HHSearch
74.11
26%
-113
- C1 -
1B0U
4
HISP_SALTY
A:
[5-245]
--
N
K
L
H
V
I
D
L
H
K
R
Y
G
----
G
----
H
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
--
N
I
----
N
L
V
R
D
KDGQLKVAD
K
N
Q
----
L
----
R
L
----
L
R
T
R
L
T
M
V
F
Q
H
F
N
-
L
W
S
H
M
T
V
L
E
N
V
-
M
E
A
P
I
Q
V
L
G
-
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
-
G
I
D
E
R
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
-
A
-
E
E
-
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
G
N
P
Q
----------------------------------------------------------------------------------------------------------------------
40
HHSearch
73.55
26%
-108
* C1 *
3TUI
1
METN_ECOLI
C:
[23-256]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
----
Q
GTRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
--
E
L
----
T
T
--------------
L
----
S
ESEL
T
K
----
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
-
A
L
P
L
E
L
-
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
-
G
L
G
D
K
H
-
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
R
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
----------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
72.60
28%
-113
- C1 -
3TUI
1
METN_ECOLI
C:
[44-275]
---------------------------
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
--
E
L
----
T
T
--------------
L
----
S
----
E
S
ELTK
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
-
A
L
P
L
E
L
-
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
-
G
L
G
D
K
H
-
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
-
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
---
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
72.07
28%
-115
- C1 -
3TUZ
1
METN_ECOLI
C:
[44-275]
---------------------------
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
--
E
L
----
T
T
--------------
L
----
S
----
E
S
ELTK
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
-
A
L
P
L
E
L
-
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
-
G
L
G
D
K
H
-
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
-
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
---
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
------------------------------------------------------------------------------------------------
45
HHSearch
69.71
27%
-110
- C1 -
2OLJ
4
?
A:
[22-251]
-
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
----
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
--
N
L
----
K
A
KDT-----------
N
----
L
----
N
K
----
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
-
T
L
A
P
M
K
-
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
-
G
L
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
-
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
----------------------------------------------------------------------------------------------------------------------
22
Fugue
67.51
24%
-99
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
QGTR
T
----
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
--
E
L
TTLS
E
S
--------------
E
----
L
----
T
K
----
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
-
A
L
P
L
E
L
-
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
-
G
L
G
D
K
H
-
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
-
N
-
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
E
R
L
QAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV------------
39
HHSearch
67.38
25%
-102
- C1 -
1OXX
21
?
K:
[1-233]
-
M
V
R
I
I
V
K
N
V
S
K
V
F
K
----
K
GK--
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
--
L
V
----
A
S
--------------
N
GKLI
V
----
P
P
----
E
D
R
K
I
G
M
V
F
Q
T
W
A
-
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
P
L
T
N
-
M
K
-
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
-
D
I
H
H
V
L
-
N
H
F
P
R
E
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
-
Q
S
R
L
-
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
Y
D
N
P
V
----------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
67.19
27%
-108
- C1 -
4P33
7
LPTB_ECOLI
A:
[1-219]
--
A
T
L
T
A
K
N
L
A
K
A
Y
K
----
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
DI
S
L
----
L
P
--------------
L
----
H
----
A
R
----
A
R
R
G
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
-
D
D
-
L
S
A
E
Q
R
E
D
R
A
N
E
L
M
E
E
F
-
H
I
E
H
L
R
-
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
-
D
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
-------------------------------------------------------------------------------------------------------------------------------
25
Fugue
66.45
23%
-94
- C1 -
1Z47
1
?
A:
[11-355]
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G---
G
----
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
--
R
-----
V
T
--------------
D
----
L
----
P
P
----
Q
K
R
N
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
G
L
R
E
-
K
R
-
V
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
-
R
L
E
S
Y
A
-
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
-
H
-
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
-
T
L
F
V
A
S
F
I
G
E
S
N
V
W
T
R
A
V
Q
N
G
R
I
E
V
AG
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
43
HHSearch
66.26
26%
-106
- C1 -
3GFO
1
ECFA3_CLOP1
A:
[5-236]
-
D
Y
I
L
K
V
E
E
L
N
Y
N
Y
S
----
D
G---
T
H
A
L
K
G
I
N
M
N
I
K
R
G
E
V
T
A
I
L
G
G
N
G
V
G
K
S
T
L
F
Q
N
F
N
G
I
L
K
P
S
S
G
R
I
L
F
D
N
K
--
P
I
----
D
Y
S
R
K
-----------
G
----
I
----
M
K
----
L
R
E
S
I
G
I
V
F
Q
D
P
D
N
Q
L
F
S
A
S
V
Y
Q
D
V
-
S
F
G
A
V
N
-
M
K
-
L
P
E
D
E
I
R
K
R
V
D
N
A
L
K
R
T
-
G
I
E
H
L
K
-
D
K
P
T
H
C
L
S
F
G
Q
K
K
R
V
A
I
A
G
V
L
V
M
E
P
K
V
L
I
L
D
E
P
T
A
G
L
D
P
M
G
V
S
E
I
M
K
L
L
V
E
M
-
Q
K
E
L
-
G
I
T
I
I
I
A
T
H
D
I
D
I
V
P
L
Y
C
D
N
V
F
V
M
K
E
G
R
V
I
L
Q
G
N
P
K
E
V
F
A
E
K
E
----------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
65.96
27%
-106
- C1 -
4P32
2
LPTB_ECOLI
A:
[1-219]
--
A
T
L
T
A
K
N
L
A
K
A
Y
K
----
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
DI
S
L
----
L
P
--------------
L
----
H
----
A
R
----
A
R
R
G
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
-
D
D
-
L
S
A
E
Q
R
E
D
R
A
N
E
L
M
E
E
F
-
H
I
E
H
L
R
-
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
-
D
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
-------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
65.86
28%
-104
- C1 -
4QC2
2
?
A:
[2-220]
--
A
T
L
T
A
K
N
L
A
K
A
Y
K
----
G
----
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
DI
S
L
----
L
P
--------------
L
----
H
----
A
R
----
A
R
R
G
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
Q
I
R
-
D
D
-
L
S
A
E
Q
R
E
D
R
A
N
E
L
M
E
E
F
-
H
I
E
H
L
R
-
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
-
R
-
D
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
-------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
65.74
24%
-102
- C1 -
2IT1
-
?
A:
[1-225]
-
M
V
E
I
K
L
E
N
I
V
K
K
F
G
----
N
----
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
E
K
--
D
V
----
T
E
--------------
L
---------
P
P
----
K
D
R
N
V
G
L
V
F
Q
N
W
A
-
L
Y
P
H
M
T
V
Y
K
N
I
-
A
F
P
L
E
L
-
R
K
-
A
P
R
E
E
I
D
K
K
V
R
E
V
A
K
M
L
-
H
I
D
K
L
L
-
N
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
-
Q
K
E
L
-
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
Y
Y
K
P
-----------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
65.74
29%
-104
- C1 -
3DHW
-
METN_ECOLI
C:
[21-252]
---------------------------
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
--
E
L
----
T
T
--------------
L
----
S
----
E
S
ELTK
A
R
R
Q
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
F
G
N
V
-
A
L
P
L
E
L
-
D
N
-
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
-
G
L
G
D
K
H
-
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
E
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
-
R
L
-
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
---
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
------------------------------------------------------------------------------------------------
38
HHSearch
65.07
23%
-107
- C1 -
3RLF
3
MALK_ECOLI
A:
[2-226]
--
A
S
V
Q
L
Q
N
V
T
K
A
W
G
----
E
----
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
I
G
E
K
--
R
M
----
N
D
--------------
T
---------
P
P
----
A
E
R
G
V
G
M
V
F
Q
S
Y
A
-
L
Y
P
H
L
S
V
A
E
N
M
-
S
F
G
L
K
L
-
A
G
-
A
K
K
E
V
I
N
Q
R
V
N
Q
V
A
E
V
L
-
Q
L
A
H
L
L
-
D
R
K
P
K
A
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
-
H
K
R
L
-
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
L
Y
H
Y
P
A
----------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
64.55
26%
-98
- C1 -
1Z47
1
?
A:
[17-238]
---
F
V
G
V
E
K
I
Y
P
G
G
A
----
R
----
S
--
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
--
R
-----
V
T
--------------
D
----
L
----
P
P
----
Q
K
R
N
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
G
L
R
E
-
K
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E
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---
Y
E
K
P
G
-------------------------------------------------------------------------------------------------------------------
50
HHSearch
64.48
28%
-114
- C1 -
1JI0
1
?
A:
[5-231]
--
I
V
L
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V
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S
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Y
G
----
A
----
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--
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----
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--------------
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----
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----
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M
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