@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0229: (2015-11-29 )
MSLIGAVLKGTKEDKEFKKQIQKALVRFVHAPEIVEEADSIKTTYSEKIDDISETAKSSIKTIKNQIDTGLVGQFGEKVKAQVDLNKGSYDDL
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........--10-......-.--.20........------30........40.......-..50...-..--...60........----70........80.....-----...90..---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
I
G
A
V
LK--GT-KE
D
K
E
F
-
K
--
K
Q
I
Q
K
A
L
V
R
F
V------H
A
P
E
I
V
E
E
A
D
S
-
I
K
T
T
Y
S
E
-
K
I
D
D
I
S
E
-
T
A
--
K
S
S
I
K
T
I
K
N
QIDT----
G
L
V
G
Q
FGE
K
V
K
A
Q
V
D
LN-----KGSYDDL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
85.61
26%
-28
- C2 -
4D10
-
CSN2_HUMAN
B:
[34-447]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VD
L
E
N
Q
Y
Y
N
S
K
A
L
K
EDDPKA
A
L
S
S
F
Q
K
V
L
E
LE
G
E
-
K
G
E
W
G
F
-
K
A
L
K
Q
M
I
K
I
N
F
K
L
T
------
N
F
P
E
M
M
N
R
Y
K
Q
-
L
L
T
Y
I
R
S
-
A
V
T
--
R
N
-
Y
S
--
E
K
S
I
N
S
I
L
D
Y
I
S
T
S
KQM
D
L
L
Q
E
F
Y
E
T
T
L
E
A
--
L
K
-----
D
A
K
N
D
R
L
W
F
K
T
N
T
K
L
G
K
L
Y
L
E
R
EEY
G
K
L
Q
K
I
L
R
Q
L
H
Q
S
CQT
Q
L
L
E
I
Y
A
L
E
I
Q
M
Y
T
A
Q
KN
N
K
K
L
K
A
L
Y
E
Q
S
L
H
I
K
S
A
I
P
H
P
L
I
M
G
V
I
R
E
C
G
G
K
M
H
L
R
E
GE
F
E
K
A
H
T
D
F
F
E
A
F
K
N
Y
D
E
S
GSPR
R
T
T
C
L
K
Y
L
V
L
A
N
M
L
M
KSGINPFDSQEAKPYKNDPEI
L
A
M
T
N
L
V
S
A
Y
Q
N
ND
I
T
E
F
E
K
I
L
K
T
N
HSNIMDD
P
F
I
R
E
H
I
E
E
L
L
R
N
I
R
T
Q
V
L
I
K
L
I
KPYTRIH
I
P
F
I
S
K
E
L
NID
V
A
D
V
E
S
L
L
V
Q
C
I
L
D
NTIHGRIDQVNQLLELDHQKRGG
A
R
Y
T
A
L
D
K
W
T
N
Q
L
N
S
L
N
Q
A
V
V
S
K
L
A
17
Fugue
76.83
16%
-21
- C2 -
2LSE
-
?
A:
[1-101]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
-
E
E
R
K
K
L
-
L
--
E
K
L
E
K
I
L
D
E
V
T
D
G
APDE
A
R
E
R
I
E
K
L
A
K
D
-
V
K
D
E
L
E
E
G
D
A
K
N
M
I
E
-
K
F
--
R
D
E
M
E
Q
M
Y
K
D
A
P
N
----
A
V
M
E
Q
L
L
E
E
I
E
K
L
L
K
K
A
GSLVP
R
G
S
Y
L
E
H
HHHHH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
70.65
16%
-17
* C2 *
2LD7
-
SIN3A_MOUSE
B:
[454-528]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
A
S
K
H
--
G
V
-
G
T
E
S
L
F
-
F
--
D
K
V
R
K
A
L
----------
R
S
A
E
A
Y
E
N
F
L
R
-
C
L
V
I
F
N
Q
-
E
V
I
S
R
A
E
-
L
V
--
Q
L
V
S
P
F
L
G
K
F
--
P
----
E
L
F
N
W
F
K
N
F
L
--------------
G
Y
K
E
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
70.25
18%
-9
- C2 -
2CWO
-
P21_BYVU
A:
[1-177]
------------------------------------------------------------------------------------------------------------------------------------------------M
K
F
F
L
KDGE
T
S
R
A
L
S
R
S
E
S
L
L
R
R
V
K
E
LGTNSQ
Q
S
E
I
S
E
C
V
D
E
F
N
E
L
A
S
F
N
H
L
L
V
T
V
E
H
R
E
W
--
M
E
-
Q
R
I
G
E
M
-
L
--
K
E
I
R
A
F
L
K
V
R
V
------
V
T
P
M
H
K
E
T
A
S
D
-
T
L
N
A
F
L
E
-
E
Y
C
R
I
T
G
L
A
R
--
E
D
A
L
R
E
K
M
R
K
V
K
S
----
V
V
L
F
H
H
S
E
L
L
K
F
E
V
T
E
N
-----
M
F
S
Y
T
E
L
L
K
LNLS
L
R
V
I
S
S
QILGMAI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
59.24
22%
26
- C2 -
2KON
-
?
A:
[1-82]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
V
A
H
Y
R
G
Y
--
E
I
-
E
P
G
H
Q
Y
-
R
--
D
D
I
R
K
Y
V
P
Y
A
L
------
I
R
K
V
G
V
P
D
R
T
P
-
I
P
T
T
Y
P
E
-
F
Y
D
L
E
A
D
-
A
E
--
R
V
S
I
A
C
A
K
I
I
I
D
S
----
H
L
D
R
H
-----------------
D
Q
G
L
A
D
L
G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
57.98
14%
32
- C2 -
1QOY
-
HLYE_ECOLI
A:
[-4-298]
S
M
A
E
I
V
A
D
K
T
V
E
V
V
K
N
A
I
E
T
A
D
G
A
L
D
L
Y
N
KYLDQVIP
W
Q
T
F
D
E
T
I
K
E
LSRFKQEYS
Q
A
A
S
V
L
V
G
D
I
K
T
L
L
M
D
S
Q
D
K
Y
F
E
A
T
Q
T
V
Y
E
W
C
G
V
A
T
Q
L
L
A
A
Y
I
L
L
F
DEYN
E
K
K
A
S
A
Q
K
D
I
L
I
K
V
L
D
D
G
I
T
K
L
N
E
A
Q
K
S
L
L
V
S
S
Q
S
F
N
N
A
S
G
K
L
L
A
L
D
S
Q
L
T
N
D
F
SEKS
S
Y
F
Q
S
Q
V
D
K
I
R
K
E
A
Y
A
G
A
AAG
V
V
V
G
P
FG
L
I
I
S
Y
S
I
A
A
G
V
V
E
--
G
--
K
L
I
P
E
L
-
K
--
N
K
L
K
S
V
Q
N
F
F
T
------
T
L
S
N
T
V
K
Q
A
N
K
D
I
D
A
A
K
L
K
-
L
T
T
E
I
A
A
-
I
G
--
E
I
K
T
E
T
E
T
T
R
F
Y
V
----
D
Y
D
D
L
M
L
S
L
L
K
E
A
A
K
K
M
-----
I
N
T
C
N
E
Y
Q
K
R
H
GKKTLF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
55.59
17%
-3
- C2 -
1PU1
-
Y677_METTH
A:
[1-91]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
R
K
L
T
E
G
--
D
L
-
D
E
I
S
S
F
L
H
--
N
T
I
S
D
F
I
L
K
R
V
------
S
A
K
E
I
V
D
I
D
I
T
-
V
L
V
E
Y
T
D
-
E
-
L
K
V
D
I
-
S
A
--
E
L
Y
L
D
E
L
S
D
A
-
D
P
----
G
I
V
D
E
A
V
D
A
A
Y
R
S
L
E
S
F
-----
L
D
G
F
R
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
54.10
16%
25
- C2 -
1E91
1
A:
[1-85]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
--
D
S
-
V
E
F
N
N
A
-
I
--
S
Y
V
N
K
I
K
T
R
F
L
------
D
H
P
E
I
Y
R
S
F
L
E
-
I
L
H
T
Y
Q
K
-
E
Q
L
H
T
K
G
-
R
P
FR
G
M
S
E
E
E
V
F
T
E
V
A
N
----
L
F
R
G
Q
E
D
L
L
S
E
F
G
Q
F
L
P
-----
E
A
K
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
50.09
35%
-76
- C3 -
1SS1
-
A:
[-1-26]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
T
A
D
N
K
F
-
N
--
K
E
Q
Q
N
A
F
W
E
I
L
------
H
L
P
N
L
N
E
E
Q
R
N
-
G
F
I
Q
S
L
K
-
D
D
P
S
Q
S
A
-
N
L
--
L
A
E
A
K
K
L
N
D
A
Q
A
P
----
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
46.93
33%
-45
- C3 -
2L82
-
?
A:
[1-31]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
Q
I
F
V
V
F
S
--
S
D
P
E
I
L
K
E
I
-
V
--
R
E
I
K
R
Q
G
V
R
V
V
------
L
L
Y
S
D
Q
D
E
K
R
R
-
R
E
R
L
E
E
F
-
E
K
Q
G
V
D
V
-
R
T
--
V
E
D
K
E
D
F
R
E
N
I
R
E
----
I
W
E
R
Y
P
Q
L
D
V
V
V
I
V
T
T
D
-----
D
K
E
W
I
K
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
46.62
26%
-37
- C4 -
3V4V
1
ITA4_HUMAN
A:
[374-415]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
G
-
I
S
S
T
F
S
Q
-
R
I
E
G
L
----------------
Q
I
S
K
----
S
L
-
S
M
F
G
Q
S
I
S
G
Q
I
D
A
D
-----
N
N
G
Y
V
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
45.99
26%
-23
* C4 *
3V4P
1
ITA4_HUMAN
A:
[374-415]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
G
-
I
S
S
T
F
S
Q
-
R
I
E
G
L
----------------
Q
I
S
K
----
S
L
-
S
M
F
G
Q
S
I
S
G
Q
I
D
A
D
-----
N
N
G
Y
V
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
40.75
6%
20
- C2 -
3S63
-
?
A:
[1-88]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
P
K
E
T
--
C
D
-
L
C
Q
I
A
L
-
R
--
T
V
F
G
H
F
G
G
N
I
P
------
S
R
R
K
L
V
H
Q
L
K
H
-
E
C
K
R
H
F
N
-
Y
R
R
R
C
L
L
-
L
M
--
K
V
N
S
D
L
I
F
R
E
M
T
D
----
G
S
F
K
--
P
M
E
V
C
L
I
M
R
E
C
-----
N
P
H
D
S
P
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
39.98
32%
13
- C1 -
3EOJ
7
BCPA_PROAE
A:
[60-106]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
G
V
V
R
F
T
------
T
K
I
E
S
V
--
V
D
S
-
V
K
N
T
L
N
V
-
E
V
D
I
A
N
E
-
T
K
--
D
R
R
I
A
V
G
E
G
S
L
S
V
----
G
D
F
S
H
S
F
S
F
E
G
S
V
V
N
M
Y
-----
Y
Y
R
S
D
A
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
36.76
23%
61
- C3 -
1DD5
1
RRF_THEMA
A:
[111-141]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
W
V
K
-
K
A
K
E
I
V
E
-
E
G
--
K
I
A
I
R
N
I
R
R
E
I
L
K
----
K
I
K
E
D
Q
K
E
G
L
I
P
E
D
D
A
K
-----
R
L
E
N
E
I
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
34.25
10%
70
- C3 -
1IS1
-
RRF_VIBPA
A:
[112-141]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
V
K
-
I
V
R
G
E
A
E
-
G
G
--
R
V
A
V
R
N
I
R
R
D
A
N
N
----
D
L
K
A
L
L
K
D
K
E
I
S
E
D
E
D
R
-----
K
A
Q
E
E
I
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
32.77
35%
76
- C3 -
2KI0
-
?
A:
[15-31]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
K
K
L
-
K
--
E
E
A
K
K
A
N
I
R
V
T
------
F
W
G
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
24.43
13%
76
* C3 *
3FX7
-
?
A:
[8-39]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
E
V
R
E
F
V
G
-
H
L
E
R
F
K
E
-
L
L
R
E
E
V
N
-
S
L
--
S
N
H
F
H
N
L
E
S
W
R
D
A
----
R
R
D
K
F
S
E
V
L
D
N
L
K
S
T
F
N
-----
E
F
D
E
A
A
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
23.37
13%
41
- C3 -
2K6L
-
?
A:
[13-43]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
--
D
Q
S
V
R
M
F
I
A
A
Q
G
G
----
G
R
K
G
D
L
S
R
F
I
E
D
A
V
R
A
Y
-----
L
F
E
R
A
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
22.19
10%
51
- C3 -
2X43
-
?
S:
[5-56]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
R
D
Q
M
K
N
A
------
A
A
-
E
A
K
D
N
V
H
D
-
K
I
Q
E
L
K
D
-
D
V
G
N
K
A
A
-
E
V
--
R
D
A
V
S
S
T
V
E
S
I
K
D
----
K
L
S
G
G
S
S
S
R
A
S
S
Y
T
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------