@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0257: (2015-11-29 )
MSIIIGLMAAMFIIRLAYLKLSIANEKALRKNGAKEYGVGVSKAITVLHIIIYFSSVTEAILTKASFNFVSVIGLSLMIFSVFMLHTVTRLLGRIWTVKLMVDKNHQFVDHWLFRVVKHPNYFLNIAPELLGVTLLCHAKYTALFVLPIYAFVIYLRIREENLLLKTIIIPNGIKKSRVT
Atome Classification :
(19 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10....-....20........30........40........50----........60....--....70.......-.80....-----....-----90---....--....100...--....110---......--..120.......130.......140.......150.......160......---.-170.......180---------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
S
I
I
I
G
L
M
A
A
M
F
I
I
R
-
L
A
Y
L
K
LSIA
N
E
K
A
L
R
KNG
A
K
EYGV
G
V
S
K
A
I
T
V
L
H
I
I
----
I
Y
F
S
S
V
T
E
A
I
L
T
KA--S
F
N
F
V
S
V
I
G
L
S
L
M
-
I
F
S
V
F
M
L
-----
H
T
V
T
-----
R
L
---
L
G
R
I
--
W
T
V
K
L
M
VDKN--
H
Q
F
V
D
H
----
W
L
F
R
V
V
--KHP
N
Y
F
LNI
A
P
E
L
L
G
V
T
L
L
CHA
K
Y
T
A
L
F
V
L
P
I
Y
A
F
V
I
Y
L
R
I
REEN
L
L
L
K
T
I
---I-IPNGIKKSRVT-----------------------------------------------------------------------------------------------
14
Fugue
91.74
19%
-136
* C9 *
4V1S
2
?
A:
[37-395]
--------------------------------------------------------------------------------------------------------------------------PGVEIGNND
Y
Y
T
W
C
K
E
T
L
S
V
I
D
K
D
LKISGTHSYYENQDRSQVSFI
W
G
N
I
F
L
L
Y
T
Y
T
E
G
I
S
L
SKSEW
S
D
A
L
M
N
C
F
L
N
F
D
N
Y
WHPNYKG
I
A
G
Y
A
TLPTSAEKVPDRF
Y
D
E
N
G
W
T
A
I
G
L
C
D
A
Y
L
A
T
Q
N
N
S
Y
L
E
K
A
K
G
A
L
A
F
S
L
S
G
E
D
N
V
L
G
G
G
---------------
I
Y
F
Q
E
T
F
V
S
L
P
V
Q
K
--
N
T
I
C
S
A
V
T
M
L
S
C
M
K
L
Y
E
I
T
Q
D
-----
R
Q
Y
L
-----
D
A
---
A
I
R
I
N
D
W
T
V
E
N
L
L
D
K
S
------
D
N
----
L
L
W
D
A
K
--
M
V
A
D
G
S
V
N
------------
T
Q
K
W
S
Y
N
A
G
F
M
I
R
S
W
L
K
M
Y
Q
A
T
K
D
E
K
Y
L
S
Q
A
------
K
A
T
L
A
S
S
E
A
K
WYNSINGALNDPGYFA
F
S
I
I
D
S
W
F
D
M
Y
D
T
DKNT
V
W
L
T
K
A
F
H
A
I
N
F
I
H
N
KLRDGNGRYPEHWGTPTTSNLEKYD
L
R
F
S
T
V
A
A
Y
M
Y
M
R
A
A
N
Y
K
R
I
L
N
12
Fugue
78.50
12%
-119
- C9 -
4A2N
3
?
B:
[1-192]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNENL
W
K
I
C
F
I
V
M
F
I
I
W
V
F
V
-
R
K
V
Y
G
T
R
A
M
K
N
K
S
K
K
K
V
R
P
N
F
E
K
S
L
V
F
L
N
F
I
G
M
V
F
L
----
P
L
T
A
V
F
S
S
Y
L
D
S
F
N
IN
L
P
D
S
I
R
L
F
A
L
I
V
T
-
F
L
N
I
G
L
F
-----
T
K
I
H
-----
K
D
---
L
G
N
N
--
W
S
A
I
L
E
I
K
D
G
--
H
K
L
V
K
E
----
G
I
Y
K
N
I
--
R
H
P
M
Y
A
H
L
W
L
W
V
I
T
Q
G
I
I
L
S
N
W
V
V
L
I
F
G
I
V
A
W
A
I
L
-
Y
F
I
R
V
P
K
E
E
E
L
L
I
E
E
---
F
-
G
D
E
Y
I
E
Y
M
G
K
T
GRLFPK-----------------------------------------------------------------------------------------
1
PsiBlast_PDB
75.66
21%
-85
- C9 -
4A2N
3
?
B:
[13-129]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
I
I
W
-
V
F
V
R
K
--
V
Y
G
T
R
A
M
K
N
K
S
K
K
K
V
R
P
N
F
E
K
S
L
V
F
L
N
F
I
GMVF
L
P
L
T
A
V
F
S
S
Y
L
D
S
F
--
N
I
N
L
P
D
S
I
R
L
F
A
L
-
I
V
T
F
L
N
I
-----
G
L
F
T
-----
K
I
HKD
L
G
N
N
--
W
S
A
I
L
E
I
K
D
G
--
H
K
L
V
K
E
----
G
I
Y
K
N
I
--
R
H
P
M
Y
A
H
L
W
L
W
V
I
T
Q
G
I
I
L
S
N
W
V
V
L
I
F
G
I
V
A
W
A
I
L
Y
F
I
R
V
P
K
E
E
E
L
L
I
E
E
F
---
G
-
D
E
Y
I
E
Y
M
G
K
T
G
-----------------------------------------------------------------------------------------------
21
Fugue
72.95
16%
-126
- C6 -
1PP7
4
?
U:
[5-118]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
E
A
S
F
T
S
R
-
L
-----
P
P
E
I
V
A
A
L
K
R
K
S
S
R
D
---
P
N
S
R
F
P
R
K
L
H
M
L
----
L
T
Y
L
A
S
N
P
Q
L
E
E
E
I
--
G
L
S
W
I
S
D
T
E
F
K
M
K
-
K
K
N
V
A
L
V
MGIKL
N
T
L
N
-----
V
N
---
L
R
D
L
--
A
F
E
Q
L
Q
H
D
K
G
GW
T
Q
W
K
R
S
----
G
F
T
R
N
S
--
V
F
E
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
65.12
9%
-108
- C7 -
2JE3
4
?
A:
[2-171]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
V
A
E
F
N
D
K
G
E
L
L
L
P
K
N
Y
R
E
W
V
M
V
G
T
Q
V
T
P
T
E
I
R
T
----
V
Y
V
D
P
E
S
Y
A
H
W
K
K
T
--
G
E
F
R
D
G
T
V
T
V
K
E
L
-
V
S
V
G
D
R
K
-----
G
P
N
G
-----
Y
F
---
M
G
D
Y
--
I
G
L
E
A
S
V
K
D
S
--
Q
R
F
A
N
E
PGN-
W
A
F
Y
I
F
YV
P
D
T
P
L
V
A
A
A
K
N
L
P
T
A
E
C
A
A
C
H
K
E
N
A
K
T
D
M
V
F
T
Q
F
Y
P
V
L
R
A
A
K
A
T
G
----------------
E
S
G
V
V
A
-----------------------------------------------------------------------------------------------
20
Fugue
56.20
13%
-47
- C5 -
1JHN
1
CALX_CANFA
A:
[17-414]
Y
K
A
P
V
P
S
G
EVYFADSFDRGTLS
G
W
I
L
S
KAKD
G
K
W
E
V
D
E
M
KETKLPGDKGL
V
L
M
S
RAKHH
A
I
S
A
K
L
NKPFLFDT
K
P
L
I
V
Q
Y
E
V
N
FQNGIECGGAYVKL
L
S
K
T
PELNLDQFHDKTPYT
I
M
F
G
P
D
K
C
GE
D
Y
K
L
H
F
I
F
R
H
K
NPKTGVY
E
E
K
H
A
K
R
PDADLKTYFTDK
K
T
H
L
Y
T
L
I
L
N
PDN
S
F
E
I
L
V
DQSIVNSGNPVN
P
S
R
E
I
E
DPEDQKPEDWDERPKIPDPDAVKPDDWNEDA
P
A
K
I
P
D
E
E
A
T
K
P
D
G
W
-
L
D
D
E
P
E
Y
V
P
D
P
D
A
E
K
P
E
D
W
D
E
D
M
D
G
E
W
E
A
--------------
P
Q
I
A
N
P
K
C
E
S
A
--
P
G
-------------
C
G
V
W
Q
R
-----
P
M
I
D
-------------------------
N
--
P
N
Y
K
G
K
----
W
K
P
P
M
I
--
D
N
P
N
Y
Q
G
I
W
K
P
R
K
I
P
N
P
D
F
-
F
E
D
L
E
P
F
K
M
T
P
F
S
A
I
G
L
E
L
W
S
M
T
S
D
I
F
F
D
N
F
---
I
-
V
C
G
D
R
R
V
V
D
D
W
A
N
D
GWGL----------------------------------------------------------------------------------------
15
Fugue
42.89
25%
84
- C9 -
2Z5I
-
?
I:
[5-40]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
A
I
K
-
K
K
M
Q
M
L
K
L
D
K
E
N
A
L
D
R
A
E
Q
L
E
N
E
V
A
R
L
K
K
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
42.43
23%
29
- C9 -
1CEU
-
VPR_HV1B9
A:
[1-51]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
-----
Q
A
P
E
DQGPQ
R
E
---
P
Y
N
D
--
W
T
L
E
L
L
E
E
L
K
--
N
E
A
V
R
H
F
P
R
I
W
L
H
S
L
G
--
Q
H
I
Y
E
T
Y
G
----------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
40.72
13%
79
* C8 *
3J2W
-
?
Q:
[10-25]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
--
H
E
I
I
L
-------
Y
Y
Y
E
--
L
Y
P
T
M
T
V
V
I
V
S
V
A
S
F
V
L
L
S
M
V
G
T
A
V
G
M
C
V
C
A
R
R
R
C
I
T
P
Y
E
L
T
P
G
A
T
V
P
F
L
L
---
S
-
L
L
C
C
V
R
T
T
K
A
------------------------------------------------------------------------------------------------
16
Fugue
37.01
38%
147
- C9 -
3PLV
-
C:
[1-21]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
S
I
E
E
T
N
E
L
R
A
S
L
GLK
L
-
I
P
P
-------------------------------------------------------------------------------------------------------
5
HHSearch
34.94
21%
86
- C9 -
3J27
-
?
B:
[35-62]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
I
L
--
R
H
P
G
F
T
-
I
-
M
A
A
I
L
A
Y
T
I
G
T
T
H
F
Q
R
A
L
I
F
I
L
L
T
A
V
A
P
-----------------------------------------------------------------------------------------------------------------------------
8
HHSearch
32.33
11%
222
- C8 -
2LSW
-
DAB2_HUMAN
A:
[34-53]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
D
E
Y
L
L
A
R
---
F
K
G
D
G
V
K
Y
K
A
K
-------------------------------------------------------------------------------------------------
4
HHSearch
30.82
15%
-5
- C9 -
2JP3
-
FXYD4_RAT
A:
[25-63]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
L
L
C
-
I
A
G
I
A
L
A
-----
L
S
G
K
-----
C
K
---
C
R
R
N
--
H
T
P
S
S
L
P
E
K
V
--
T
P
L
I
T
P
----
G
S
A
S
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
24.99
40%
601
- C3 -
1V8H
-
?
A:
[24-33]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
A
--
Q
H
P
N
E
P
-
G
T
R
R
D
A
E
G
K
L
I
P
A
K
Y
I
N
L
V
E
V
Y
F
E
G
E
K
V
A
E
A
R
P
G
P
S
T
S
A
N
P
L
Y
A
---
F
-
K
F
K
A
E
K
A
G
T
F
T
-----------------------------------------------------------------------------------------------
3
HHSearch
22.03
10%
480
- C1 -
2OXG
1
?
Z:
[24-33]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
I
--
S
H
K
M
E
S
-
G
Q
R
K
D
A
D
G
K
L
I
P
R
S
I
I
N
R
F
T
C
E
L
N
G
V
N
V
V
D
V
A
I
D
P
A
V
S
T
N
P
Y
F
E
---
F
-
D
A
K
V
D
A
A
G
E
F
K
-----------------------------------------------------------------------------------------------
6
HHSearch
21.51
13%
165
- C9 -
2ZXE
-
?
G:
[27-41]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
V
L
C
-
V
I
G
I
I
I
L
-----
L
A
G
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
21.39
44%
794
- C2 -
2KLQ
-
MCM6_HUMAN
A:
[810-818]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
V
--
V
N
P
N
Y
L
------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
18.43
17%
688
- C4 -
2PKA
-
KLK_PIG
A:
[67-78]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
T
A
D
F
--
P
H
P
G
F
N
L
S
----------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
0.00
7%
0
- C- -
1QD6
-
?
?:
[1-13]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVRGS
I
I
A
N
M
L
QE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------