@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0278: (2015-11-29 )
MFLSIMAGVIAFVLTVIAIPRFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLIVALLVSLIFSIILSKENSGNLGATFGILSVVLIYGIIGFLDDFLKIFKQINEGLTPKQKMSLQLIAGLIFYFVHVLPSGTSAINIFGFYLEVGYLYAFFVLFWVVGFSNAVNLTDGIDGLASISVVISLITYGIIAYNQTQFDILLIIVIMIGALLGFFVFNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLFIGFVYVFETSSVMLQVAYFKYTKKKTGVGKRIFRMTPFHHHLELGGVSGKGNKWSEWKVDAFLWAIGIFMSAITLAILYL
Atome Classification :
(16 SA)
---------.........10........-20.........30.....-...40.----.......50..---......60-.........70...--......80......-----..--90-........-100---......---------.110----------.-----....---..120-----..---.....130...-...--------.140...----..----..150...--....160.....-...170--------.........180.......190....-----.-----..200---------........210.......-----220.......230..-------------------.....240.......250.....--..260....---...270........280..-....--.290........300.-.....------.310..------.......320-----.......-.330....------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------
M
F
L
S
I
M
A
G
V
I
A
F
V
L
T
V
I
A
I
-
P
-
R
F
I
K
F
Y
Q
L
K
K
IG
G
Q
Q
M
-
H
E
D
V
K
Q
----
H
L
A
KAGTPTM
G
---
G
T
V
F
L
I
V
--
A
L
L
V
S
L
I
F
S
I
-
I
LS--KENSGNL
G
A
T
F
G
I
L
-----
S
V
--
V
L
-
I
Y
G
I
I
G
F
L
-
D
D
F
---
L
K
I
F
K
Q
---------
I
NEG----------L-----T
P
K
Q
---
K
M
S
L
Q
-----
L
I
---
A
G
L
I
F
Y
F
V
H
VL-PSG--------T
S
A
I
N
I
F
----
G
F
----
Y
L
E
V
G
Y
L
Y
--
A
F
F
V
L
F
-
W
V
VGF-SNAV----------NLTDGI
D
G
L
A
S
I
S
V
V
I
S
L
I
T
Y
G
I
IAY-----N-----QT
Q
F
----------
D
I
L
L
I
I
V
I
M
I
G
A
L
L
G
F
F
V
-----FNHK
P
A
K
V
F
MG
D
V
G
S
-------------------
L
A
L
G
A
M
L
A
A
I
S
I
A
L
RQE
W
T
L
L
F
I
--
G
F
V
Y
V
FETS---
S
V
M
L
Q
-
V
A
Y
F
K
YTKKKTGV-G
K
R
I
--
F
R
M-TPF
H
H
H
L
E
LGGV-SGKGN------KW--SE------W
K
V
D
A
F
L
W
A
------
I
G
I
F
M
S
A
-
I
T
L
A
I
LYL------
11
Fugue
97.37
40%
-168
- C6 -
4J72
3
MRAY_AQUAE
A:
[20-363]
F
A
F
N
V
L
K
Y
I
T
F
R
S
F
T
A
V
L
I
A
F
F
L
T
L
V
L
S
-
P
-
S
F
I
N
R
L
------------------------
K
K
Y
T
P
T
M
G
---
G
I
V
I
L
I
V
--
V
T
L
S
T
L
L
L
M
----------
R
W
D
I
K
Y
T
W
V
V
L
-----
L
S
--
F
L
-
S
F
G
T
I
G
F
W
-
D
D
Y
---
V
K
L
K
N
-----------
K
K
G
----------
I
-----
S
I
K
T
---
K
F
L
L
Q
-----
V
L
---
S
A
S
L
I
S
V
L
I
Y
Y
-
W
A
D
--------
I
D
T
I
L
Y
F
----
P
F
FKE
L
Y
V
D
L
G
V
L
Y
--
L
P
F
A
V
F
-
V
I
V
G
S
-
A
N
A
V
----------
N
L
T
D
G
L
D
G
L
A
I
G
P
A
M
T
T
A
T
A
L
G
V
V
A
Y
-----
A
V
G
H
S
K
I
A
Q
Y
L
N
I
P
Y
V
P
YA
G
E
L
T
V
F
C
F
A
L
V
G
A
G
L
G
F
L
W
-----
F
N
S
F
P
A
Q
M
F
M
G
D
V
G
S
-------------------
L
S
I
G
A
S
L
A
T
V
A
L
L
T
K
S
E
F
I
F
A
V
A
--
A
G
V
F
V
F
E
T
I
---
S
V
I
L
Q
-
I
I
Y
F
R
W
T
G
------
G
K
R
L
--
F
K
R
-
A
P
F
H
H
H
L
E
L
N
G
--------------
L
--
P
E
------
P
K
I
V
V
R
M
W
I
------
I
S
I
L
L
A
I
-
I
A
I
S
M
L
K
-------
1
PsiBlast_PDB
89.84
37%
-174
- C6 -
4J72
3
MRAY_AQUAE
A:
[30-339]
----------
F
R
S
F
T
A
V
L
I
A
F
F
L
T
L
V
L
S
-
P
-
S
F
I
N
--
R
L
----------------------
K
K
Y
T
P
T
M
G
---
G
I
V
I
L
I
V
--
V
T
L
S
T
L
L
L
M
----------
R
W
D
I
K
Y
T
W
V
V
L
-----
L
S
--
F
L
-
S
F
G
T
I
G
F
W
-
D
D
Y
---
V
K
L
--
K
---------
N
K
K
G
----------
I
-----
S
I
K
T
---
K
F
L
L
Q
V
L
S
A
S
L
I
---
S
V
L
I
Y
Y
W
A
D
I
--------------
D
T
I
L
Y
F
----
P
F
FKE
L
Y
V
D
L
G
V
L
Y
--
L
P
F
A
V
F
-
V
I
V
G
S
-
A
N
A
V
----------
N
L
T
D
G
L
D
G
L
A
I
G
P
A
M
T
T
A
T
A
L
G
V
V
A
Y
A
V
G
H
S
K
-----
I
A
Q
Y
L
N
I
P
Y
V
P
YA
G
E
L
T
V
F
C
F
A
L
V
G
A
G
L
G
F
L
W
-----
F
N
S
F
P
A
Q
M
F
M
G
D
V
G
S
-------------------
L
S
I
G
A
S
L
A
T
V
A
L
L
T
K
S
E
F
I
F
A
V
A
--
A
G
V
F
V
F
E
T
I
---
S
V
I
L
Q
-
I
I
Y
F
R
W
T
G
------
G
K
R
L
--
F
K
R
-
A
P
F
H
H
H
L
E
L
N
G
L
-
P
E
P
K
I
------
V
V
--
R
M
------
W
I
I
S
I
L
L
A
I
------
I
A
I
S
M
L
K
---------------
14
Fugue
64.17
18%
-130
- C6 -
5A07
3
?
A:
[40-434]
----D
H
D
A
E
V
L
D
S
I
M
D
R
L
H
E
P
L
Y
E
K
D
T
F
-
D
-
P
N
E
V
L
A
E
N
K
Q
L
Y
E
E
F
L
-
L
Q
E
I
S
E
PKVD
N
L
V
R
S
G
D
P
L
A
G
KAK
G
T
I
L
S
L
V
RN
S
D
L
E
D
I
I
S
S
I
Q
Q
L
E
--
E
E
Y
N
K
N
F
G
Y
P
Y
T
F
L
N
DEEF
T
D
--
E
F
-
K
D
G
I
K
S
I
L
P
K
D
R
---
V
V
E
F
G
T
---------
I
G
P
D
NWNMPDSID
R
E
-----
R
Y
D
Q
---
E
M
D
K
M
-----
S
K
---
E
N
I
Q
Y
A
E
V
---------------
E
S
Y
H
N
M
C
----
R
F
----
Y
S
K
E
F
Y
H
H
--
P
L
L
S
K
Y
K
Y
V
W
R
L
-
E
P
N
V
----------
N
F
Y
C
K
I
N
Y
D
V
F
Q
F
M
N
K
N
D
K
I
Y
G
F
V
L
-------------
N
L
Y
----------
D
S
P
Q
T
I
E
T
L
W
T
S
T
M
D
F
V
E
E
H
PNY
L
N
V
N
G
A
F
A
W
L
K
D
N
S
Q
N
P
K
N
Y
D
Y
T
QGYSTCHFWTN
F
E
I
V
D
L
D
F
L
R
S
E
P
Y
E
K
Y
M
Q
Y
L
E
E
K
G
G
F
Y
Y
E
R
W
G
D
---
A
P
V
R
S
-
L
A
L
A
L
F
A
D
K
S
S
I
H
-
W
F
R
D
IG
Y
H
H
-
T
P
Y
T
N
C
P
T
C
P
A
D
-
S
D
R
C
N
GNCVPG
K
F
--
T
P
------
W
S
D
L
D
N
Q
N
C
------
Q
A
T
W
I
R
H
S
M
S
E
E
E
L
E
M
Y-----
12
Fugue
61.98
14%
-129
- C6 -
4LDV
13
ARFA_ARATH
A:
[16-356]
--S
D
A
L
C
R
E
L
W
H
A
C
A
G
P
L
V
T
L
P
R
E
G
E
R
V
-
Y
-
Y
F
P
E
G
H
M
E
Q
L
--
E
A
S
M
-
H
Q
G
L
E
Q
----
Q
M
P
S
F
N
L
P
S
K
----------------
I
L
C
K
V
I
N
-
I
Q
R
--
R
A
E
T
D
E
V
Y
A
Q
I
T
L
L
-----
P
E
--
L
D
-
Q
S
E
P
T
S
P
D
-
A
P
V
---
Q
E
T
V
H
S
---------
F
C
K
T
----------
L
-----
T
A
S
D
---
T
S
T
H
G
-----
G
F
---
S
V
L
R
R
H
A
D
D
C
L
-
P
P
L
--------
D
M
S
Q
Q
P
P
----
W
Q
----
E
L
V
A
T
D
L
H
N
S
E
W
H
F
R
H
-
I
F
R
G
Q
-
P
R
R
H
----------
L
L
T
T
G
W
S
V
F
V
S
S
K
------------------
K
-----
L
V
A
G
----------
D
A
F
I
F
L
R
G
E
N
E
E
-
L
R
V
G
V
-----
R
R
H
M
P
S
S
V
----
I
S
S
-------------------
H
S
M
H
I
G
V
L
A
T
A
A
H
A
I
T
T
G
T
I
F
S
V
--
F
Y
K
P
R
T
S
R
S
---
E
F
I
V
S
-
V
N
R
Y
L
E
A
K
T
Q
K
L
S
-
V
G
M
R
--
F
K
M
-
R
F
K
R
F
S
G
T
I
V
G
V
Q
E
N
K
S
S
------
V
W
HD
S
E
------
W
R
S
L
K
V
Q
W
D
EPSSVF
R
P
E
R
V
S
P
-
W
E
L
E
P
L
N
-------
2
PsiBlast_PDB
58.84
24%
-172
* C7 *
2EWV
1
?
A:
[33-231]
----------------------------------------------------------------------------------------------------------
T
A
G
A
P
-----
P
A
--
V
R
-
I
D
G
Y
I
K
F
L
-
K
D
F
---
P
R
L
T
P
E
---------
D
T
Q
K
----------
L
A
Y
SVM
S
E
K
H
---
R
Q
K
L
E
-----
E
N
---
G
Q
V
D
F
S
F
-
G
V
R
-
G
V
G
--------
R
F
R
A
N
V
F
YQRG
S
V
----
A
A
A
L
R
S
L
P
--
A
E
I
P
E
F
-
K
K
L
G
L
-
P
D
K
V
L
E
L
C
H
RK
M
G
L
I
L
V
T
G
P
T
G
S
G
K
S
T
T
I
A
S
M
I
D
Y
----
I
-----
N
-----
Q
T
K
S
----------
Y
H
I
I
T
I
E
D
P
I
E
-----
Y
V
-----
F
K
H
K
K
S
I
V
N
Q
R
E
V
G
E
--------------------
D
T
K
S
F
A
D
A
L
R
A
A
L
R
E
D
P
D
V
I
F
V
--
G
E
M
R
D
L
E
T
V
---
E
T
A
L
R
-
A
A
E
T
G
H
L
V
F
G
T
L
H
-
T
N
T
A
--
I
D
T
-
I
H
R
I
V
D
I
F
P
L
N
Q
-
Q
E
Q
V
R
------
I
V
--
L
S
------
F
I
L
Q
G
I
I
S
Q
------
R
L
L
P
K
I
G
-
G
G
R
V
L
A
Y
E
------
13
Fugue
58.69
15%
-150
- C6 -
4BVA
3
CRYM_MOUSE
A:
[24-334]
----------------
K
R
A
P
A
F
L
S
A
E
E
V
-
Q
-
D
H
L
R
-------
S
S
S
L
L
-
I
P
P
L
E
A
----
A
L
A
N
F
S
K
G
P
D
G
---
G
----------
V
M
Q
P
V
R
T
V
-
V
P
V
--
A
K
H
R
G
F
L
G
V
M
P
A
Y
S
-----
A
A
ED
A
L
-
T
T
K
L
V
T
F
Y
-
E
S
H
Q
A
S
V
L
L
F
D
P
---------
S
N
G
S
----------
L
-----
L
A
V
M
D
G
N
V
I
T
A
K
-----
R
T
---
A
A
V
S
A
I
A
T
K
L
L
K
P
P
G
--------
S
D
V
L
C
I
L
----
G
A
----
G
V
Q
A
Y
S
H
Y
--
E
I
F
T
E
Q
-
F
S
F
K
E
-
V
R
M
W
----------
N
R
T
R
E
N
A
E
K
F
A
S
T
V
Q
G
D
V
R
V
C
S
S
V
Q
E
-----
A
-----
V
T
G
A
----------
D
V
I
I
T
V
T
M
A
------------------
T
E
P
I
L
F
G
E
W
---------------------
V
K
P
G
A
H
I
N
A
V
G
-
A
S
R
P
D
W
R
E
L
-----------
D
D
---
E
L
M
R
Q
-
A
V
L
Y
V
D
S
R
E
A
A
L
K
-
E
S
G
D
--
V
L
L
-
S
G
A
D
I
F
A
E
L
G
E
V
-
I
-
S
G
A
------
K
P
--
A
H
------
C
E
K
T
T
V
F
K
S
------
L
G
M
A
V
E
D
-
L
V
A
A
K
L
V
Y
D
S
W
S
S
G
17
Fugue
56.47
15%
-136
- C6 -
4ART
4
Y273_ATV
A:
[22-270]
-------------------------------------
I
D
A
T
N
D
E
E
K
L
-
A
D
I
V
E
N
----
E
I
E
K
E
I
R
K
I
E
N
---
F
Y
Y
Y
I
L
R
DG
K
I
Y
P
A
S
D
Y
D
I
-
E
V
E
--
K
G
K
R
S
A
N
D
I
Y
A
F
V
E
-----
T
D
--
V
T
----------
R
D
F
---
D
E
F
L
F
D
---------
I
D
Y
G
----------
L
-----
P
---------------------------------------------
S
I
S
D
I
L
----
K
F
----
Y
L
E
K
A
---------------
G
F
-
R
I
A
N
----------
E
V
P
T
P
N
---------
L
K
Y
Y
I
H
A
V
V
E
F
-----
P
-----
Q
--------------
Y
L
A
V
N
I
Y
D
I
D
S
L
A
R
A
L
R
-----
I
P
Q
I
V
E
Q
K
L
-
G
N
K
P
R
-------------------
T
I
T
A
D
E
F
N
D
I
E
R
I
V
A
E
E
Q
P
I
L
-
A
--
G
Y
-----
T
Y
---
D
E
A
L
R
-
I
P
Y
H
Y
Y
V
D
H
N
N
S
F
-
K
D
D
A
--
L
K
I
-
A
H
A
Y
L
Q
L
------------------
F
--
P
T
------
P
Y
Q
V
C
Y
E
W
K
------
A
R
W
F
N
K
I
-
D
C
L
K
L
E
R
L
K-----
18
Fugue
54.91
20%
-58
- C5 -
3UP6
-
?
A:
[35-358]
-------T
R
A
Q
L
S
I
--
D
L
V
N
N
V
E
Q
Q
E
K
I
N
S
M
R
F
I
V
F
G
S
T
P
--
G
G
V
R
L
-
D
V
N
E
H
I
----
L
L
S
T
P
E
T
A
T
D
I
---
D
A
Q
L
L
E
V
--
T
S
S
N
D
I
L
V
V
V
-
I
A
N
EP
Q
S
L
T
S
Q
L
D
G
I
A
N
L
L
-----
T
L
--
Q
E
M
I
Y
D
I
S
S
I
L
-
N
S
D
---
G
Q
I
I
S
A
T
G
M
P
M
T
G
V
I
R
D
I
S
----------
I
-----
A
P
D
E
---
T
K
T
V
Q
M
----
V
I
E
R
A
V
A
R
V
D
V
F
I
E
A
I
-
D
G
G
A
V
T
G
Y
T
AG
S
T
S
V
T
L
H
----
N
F
----
S
H
D
S
-------
Y
F
V
--------
M
G
N
V
G
----------
N
G
T
R
D
N
A
D
S
S
K
--------
N
Y
G
K
V
K
E
-----
D
-----
V
S
E
S
----------
N
--
L
L
T
H
S
W
T
A
A
T
T
E
T
W
A
-----
Y
S
S
A
P
G
----------------------------------------
A
E
N
R
K
L
L
C
S
F
Y
--
T
A
E
R
L
F
K
S
D
YSD
R
L
S
I
S
M
A
N
V
L
K
G
P
S
D
V
T
G
I
T
G
K
V
I
--
E
S
V
-
T
K
V
D
-----
G
T
G
-
S
P
T
A
Q
------
P
F
--
T
E
IRRN
N
V
Y
Q
V
T
A
R
V
G
K
------
I
G
I
Q
I
L
T
-
I
S
V
E
D
W
--------
15
Fugue
45.32
19%
-41
- C6 -
3A1Y
-
RL12_PYRHO
A:
[1-58]
-----------------------------
M
-
E
Y
V
Y
A
A
L
L
L
H
S
V
G
K
E
I
N
E
E
N
L
K
A
----
V
L
Q
A
A
G
V
E
P
E
E
---
A
R
I
K
A
L
V
--
A
A
L
E
G
V
N
I
D
E
-
V
I
E
--
K
A
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
44.47
17%
-97
* C6 *
2RRE
-
NVL_MOUSE
A:
[1-74]
--------------
M
K
P
R
P
G
V
F
V
D
R
K
L
K
-
Q
-
R
V
I
Q
Y
L
S
S
N
R
C
G
K
Y
V
D
-
T
G
I
L
A
S
----
D
L
Q
R
L
Y
S
V
D
Y
G
---
R
R
K
R
N
A
F
--
R
I
Q
V
E
K
V
F
S
I
-
I
S
S
--
E
K
E
L
K
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
35.81
40%
192
- C7 -
2LS4
-
A:
[4-23]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
C
I
A
V
A
A
G
A
G
T
G
Y
F
L
-----
F
S
W
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
33.18
16%
151
- C6 -
2Z5I
-
?
I:
[5-40]
------------------------
M
D
A
I
-
K
-
K
K
M
Q
M
L
K
L
D
K
E
N
A
L
D
R
-
A
E
Q
L
E
N
----
E
V
A
R
L
K
K
L
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
31.74
28%
179
- C4 -
1QK6
-
A:
[1-33]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-
C
K
G
V
--
F
D
A
C
T
P
G
K
N
E
C
C
P
N
R
V
-
C
S
D
K
H
------
K
W
--
C
K
------
W
K
L
----------------------------------
10
HHSearch
20.91
35%
654
- C2 -
3U43
-
IMM2_ECOLX
A:
[76-92]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
N
-
G
K
S
G
--
F
K
Q
-
G
L
E
H
H
H
H
H
H
----------------------------------------------------------------
3
HHSearch
15.76
29%
765
- C3 -
3NK4
2
?
C:
[17-30]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
V
L
--
L
S
A
-
D
H
H
H
H
H
H
------------------------------------------------------------------
6
HHSearch
0.50
36%
1210
- C1 -
2HZS
-
MED8_YEAST
I:
[16-26]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
--
F
T
G
-
E
K
H
H
H
H
H
H
-----------------------------------------------------------------