@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0280: (2015-11-29 )
MFKKIILSIATIAATASLAVSVQASEKVELKVATDSDTAPFTYQKDGKFKGYDVDVVKAVFKGSKYKVTFKTVPFDTISTGIDAGKFDLSANDFSYNKERAEKYLFSDPISRSNYAVVGKKGSHYKSLSDLSGKSTEVLSGVNYAQVLENWNKNHPNKKPIKIKYVSGTTGVTSRLKNIESGKIDFILYDAISSDYIVKDQSLNLSVSPLKGKIGNNKDGLEYLLLPKDKKGKTLQKFINKRIKVLKENGTLARLSKQYFGGDYVSNIDK
Atome Classification :
(20 SA)
.........10........20--.........30........40..-.-.-.-...50........60..-.---.....70..-.-.....80..-......90.....-...100--.......110.-....---..120-.--.-.-....130.......140.......150.......160....-...-170.......180.......190..-...-..---200.-.-.--...---..210...-....220.-......230.......240.......250.......260.......270-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
F
K
K
I
I
L
S
I
A
T
I
A
A
T
A
S
L
A
V
---
S
V
QAS
E
K
V
E
L
K
V
ATDSDTA
P
F
T
Y-Q-K-D-GKFKG
Y
D
V
D
V
V
K
A
V
FKG-S---
K
Y
K
V
T
F
K
TV-P-F
D
T
ISTGID-AG
K
F
DLSANDFSY-
N
K
E
R
A
E
--
K
Y
LFSDPISRS-
N
Y
A
V
---VGKKG-S--H-Y-K
S
L
S
DLSGKS
T
E
V
LSGV
N
Y
A
Q
V
L
E
N
W
NKNHPNKK
P
I
K
I
K
Y
V-SGT-T
G
V
T
S
R
L
K
NIESG
K
I
D
F
I
L
Y
DAISS-
D
Y
I
-
V
K---D-QS-L-
N
--
L
S
V---SPLKGKIG-NNKDG
L
E
Y
-
L
LLPKDKK
G
K
T
L
Q
K
F
I
N
K
R
I
K
V
L
KEN
G
T
L
A
R
L
S
K
Q
YFGG
D
Y
V
SNIDK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
97.13
40%
-76
- C1 -
4C0R
11
?
B:
[7-235]
----------------------------------
L
A
T
V
G
T
T
N
P
F
S
Y
-
E
-
K
-
K
-
G
K
L
T
G
Y
D
I
E
V
A
K
E
V
F
K
A
-
S
D--
K
Y
D
V
K
Y
Q
K
T
-
E
-
W
T
S
I
F
S
G
L
D
-
S
D
K
Y
Q
I
G
A
N
N
I
S
Y
-
T
K
E
R
A
N
--
K
Y
L
Y
S
N
P
T
A
S
N
-
P
L
V
L
---
V
V
P
K
D
-
S
--
D
-
I
-
K
S
Y
N
D
I
A
G
H
S
T
Q
V
V
Q
G
N
T
T
V
P
M
L
Q
K
F
N
K
N
H
E
N
N
Q
-
V
K
L
N
F
T
-
S
---
E
D
L
A
H
Q
I
R
N
V
S
D
G
K
Y
D
F
K
I
F
E
K
I
S
A
-
E
T
I
-
I
K
---
E
-
Q
G
-
L
D
N
--
L
K
V
---
I
D
L
P
S
-----
D
Q
K
P
Y
V
Y
-
F
I
F
A
Q
D
Q
K
D
--
L
Q
K
F
V
N
K
R
L
K
K
L
Y
E
N
G
T
L
E
K
L
S
K
K
Y
L
G
G
S
Y
L
P
D
K
K
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
94.11
37%
-76
- C1 -
4EQ9
1
?
A:
[7-239]
-----------------------------
K
K
E
I
I
V
A
T
N
G
S
P
R
P
F
I
Y
-
E
-
E
-
N
-
G
E
L
T
G
Y
E
I
E
V
V
R
A
I
F
K
D
-
S
D--
K
Y
D
V
K
F
E
K
T
-
E
-
W
S
G
V
F
A
G
L
D
-
A
D
R
Y
N
M
A
V
N
N
L
S
Y
-
T
K
E
R
A
E
--
K
Y
L
Y
A
A
P
I
A
Q
N
P
N
V
L
V
---
V
K
K
D
D
-
S
--
S
-
I
-
K
S
L
D
D
I
G
G
K
S
T
E
V
V
Q
A
T
T
S
A
K
Q
L
E
A
Y
N
A
E
H
T
D
-
N
P
T
I
L
N
Y
T
-
K
A
D
F
Q
Q
I
M
V
R
L
S
D
---
G
Q
F
D
Y
K
I
F
D
K
I
G
V
-
E
T
V
-
I
K
---
N
-
Q
G
-
L
D
N
--
L
K
V
---
I
E
L
P
-----
S
D
Q
Q
P
Y
V
Y
-
P
L
L
A
Q
G
Q
--
D
E
L
K
S
F
V
D
K
R
I
K
E
L
Y
K
D
G
T
L
E
K
L
S
K
Q
F
F
G
D
T
Y
L
P
A
E
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
74.66
30%
-61
- C1 -
4G4P
2
?
A:
[18-243]
-------------------------
Q
G
M
E
G
K
K
Y
T
I
G
T
D
L
T
F
A
P
F
E
F
-
Q
-
D
-
S
K
G
K
Y
I
G
I
D
V
D
L
L
D
A
I
A
K
D
-
Q
---
D
F
E
V
D
L
K
P
L
-
G
-
F
D
S
A
V
Q
A
I
Q
-
S
K
Q
I
D
G
M
I
A
G
M
S
I
-
T
D
E
R
K
K
--
S
F
D
F
S
D
P
Y
F
D
S
-
G
L
Q
L
---
A
V
K
K
G
-
N
--
D
K
I
-
K
S
Y
D
D
L
K
G
K
T
V
A
A
K
V
G
T
E
S
A
N
F
L
E
----
K
N
K
E
K
Y
D
Y
T
I
K
N
F
-
D
D
A
-
T
G
L
---
Y
K
A
L
E
N
G
E
A
D
A
I
V
D
D
Y
P
V
L
-
G
Y
A
-
V
K
---
N
G
Q
K
-
L
-
Q
--
L
-----------
V
G
-
D
K
E
T
G
S
S
Y
-
G
F
A
V
K
K
G
Q
N
P
E
L
I
K
K
F
N
A
G
L
K
N
L
K
D
N
G
T
Y
D
K
I
L
N
N
Y
L
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
72.41
23%
-57
- C1 -
3VV5
1
?
A:
[31-257]
-------------------------
E
I
K
R
S
G
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
-
F
-
D
E
R
-
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
-
L
---
G
L
K
P
R
W
I
A
Q
-
S
-
F
D
T
L
L
I
Q
L
N
-
Q
G
R
F
D
F
V
I
A
S
H
G
I
-
T
E
E
R
A
R
--
A
V
D
F
T
N
P
H
Y
C
T
-
G
G
V
I
---
V
S
R
K
G
-
G
----
P
-
R
T
A
K
D
L
Q
G
K
V
V
G
V
Q
V
G
T
T
Y
M
E
A
A
Q
K
I
P
---
G
---
I
K
E
V
R
T
Y
-
Q
-
R
---
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
-
K
E
A
-
I
K
---
E
-
R
K
L
E
-
N
--
T
L
Q
-----
V
G
E
L
----
V
-
F
Q
E
R
V
A
M
A
V
A
K
G
N
--
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
R
C
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
72.38
25%
-51
- C1 -
3VV5
1
?
A:
[37-256]
-------------------------------
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
-
E
-
R
-
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
-
L
---
G
L
K
P
R
W
I
A
Q
-
S
-
F
D
T
L
L
I
Q
L
N
-
Q
G
R
F
D
F
V
I
A
S
H
G
I
-
T
E
E
R
A
R
--
A
V
D
F
T
N
P
H
Y
C
T
-
G
G
V
I
---
V
S
R
K
G
-
G
--
P
---
R
T
A
K
D
L
Q
G
K
V
V
G
V
Q
V
G
T
T
Y
M
E
A
A
Q
--------
K
I
P
-
G
I
K
E
V
-
R
T
Y
-
Q
R
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
-
K
E
A
-
I
K
---
E
-
R
K
-
L
-
E
NT
L
Q
V
---
G
E
L
V
F
Q
---------
E
R
-
V
A
M
A
V
A
K
G
N
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
R
C
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
71.60
25%
-50
- C1 -
3VVF
3
?
A:
[37-256]
-------------------------------
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
-
E
-
R
-
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
-
L
---
G
L
K
P
R
W
I
A
Q
-
S
-
F
D
T
L
L
I
Q
L
N
-
Q
G
R
F
D
F
V
I
A
S
H
G
I
-
T
E
E
R
A
R
--
A
V
D
F
T
N
P
H
Y
C
T
-
G
G
V
I
---
V
S
R
K
G
-
G
--
P
---
R
T
A
K
D
L
Q
G
K
V
V
G
V
Q
V
G
T
T
Y
M
E
A
A
Q
--------
K
I
P
-
G
I
K
E
V
-
R
T
Y
-
Q
R
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
-
K
E
A
-
I
K
---
E
-
R
K
-
L
-
E
NT
L
Q
V
---
G
E
L
V
F
Q
---------
E
R
-
V
A
M
A
V
A
K
G
N
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
R
C
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
71.22
27%
-50
- C1 -
4LA9
7
?
A:
[29-250]
--------------------------
A
E
T
T
V
--
K
I
A
S
D
S
S
Y
A
P
F
E
F
-
Q
-
N
G
Q
-
K
K
W
V
G
I
D
V
D
I
M
Q
E
V
A
K
I
-
N
---
D
W
K
L
E
M
S
Y
P
-
G
-
F
D
A
A
L
Q
N
L
K
-
A
G
Q
V
D
G
I
I
A
G
M
T
I
-
T
D
E
R
K
E
--
T
F
D
F
S
N
P
Y
Y
T
S
-
A
L
T
I
---
A
T
T
K
D
-
S
--
K
-
L
-
S
D
Y
S
D
L
K
G
K
A
V
----
G
A
K
N
G
T
A
A
Q
T
W
L
Q
E
N
Q
K
K
Y
G
Y
T
I
K
T
Y
-
S
D
G
-
V
H
M
F
A
A
L
---
S
S
G
N
I
A
G
A
M
D
E
V
P
V
I
-
S
Y
A
-
M
K
Q
GQ
D
-
L
A
-
M
-
N
--
F
P
S
---
I
S
L
P
G
G
Y
G
-----------
F
A
V
M
K
G
K
N
S
T
L
V
D
G
F
N
K
A
L
A
E
M
K
S
N
G
D
Y
D
K
I
L
K
K
Y
G
I
T
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
70.23
25%
-49
- C1 -
3VVE
2
?
A:
[37-256]
-------------------------------
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
-
E
-
R
-
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
-
L
---
G
L
K
P
R
W
I
A
Q
-
S
-
F
D
T
L
L
I
Q
L
N
-
Q
G
R
F
D
F
V
I
A
S
H
G
I
-
T
E
E
R
A
R
--
A
V
D
F
T
N
P
H
Y
C
T
-
G
G
V
I
---
V
S
R
K
G
-
G
--
P
---
R
T
A
K
D
L
Q
G
K
V
V
G
V
Q
V
G
T
T
Y
M
E
A
A
Q
--------
K
I
P
-
G
I
K
E
V
-
R
T
Y
-
Q
R
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
-
K
E
A
-
I
K
---
E
-
R
K
-
L
-
E
NT
L
Q
V
---
G
E
L
V
F
Q
---------
E
R
-
V
A
M
A
V
A
K
G
N
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
R
C
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
70.04
25%
-46
- C1 -
3VVD
1
?
A:
[37-256]
-------------------------------
E
I
R
I
G
T
E
G
A
F
P
P
F
N
Y
F
D
-
E
-
R
-
N
Q
L
T
G
F
E
V
D
L
G
N
A
I
A
E
R
-
L
---
G
L
K
P
R
W
I
A
Q
-
S
-
F
D
T
L
L
I
Q
L
N
-
Q
G
R
F
D
F
V
I
A
S
H
G
I
-
T
E
E
R
A
R
--
A
V
D
F
T
N
P
H
Y
C
T
-
G
G
V
I
---
V
S
R
K
G
-
G
--
P
---
R
T
A
K
D
L
Q
G
K
V
V
G
V
Q
V
G
T
T
Y
M
E
A
A
Q
--------
K
I
P
-
G
I
K
E
V
-
R
T
Y
-
Q
R
D
P
D
A
L
Q
D
L
L
A
G
R
I
D
T
W
I
T
D
R
F
V
A
-
K
E
A
-
I
K
---
E
-
R
K
-
L
-
E
NT
L
Q
V
---
G
E
L
V
F
Q
---------
E
R
-
V
A
M
A
V
A
K
G
N
K
S
L
L
D
A
L
N
R
A
L
A
E
L
M
Q
D
G
T
Y
A
R
I
S
Q
K
W
F
G
E
D
V
R
C
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
69.08
23%
-47
- C1 -
4P0G
9
MLTF_PSEAE
A:
[7-435]
------------
A
P
T
A
L
E
R
V
---
Q
K
E
G
----
V
L
R
V
I
T
R
N
S
P
A
T
Y
F
Q
-
D
-
R
-
N
-
G
-
E
T
G
F
E
Y
E
L
A
K
R
F
A
E
R
-
L
---
G
V
E
L
K
I
E
T
A
-
D
N
L
D
D
L
Y
A
Q
L
S
R
E
G
G
P
A
L
A
A
A
G
L
T
P
-
G
R
E
D
D
A
--
S
V
R
Y
S
H
T
Y
L
D
V
-
T
P
Q
I
---
I
Y
R
N
G
-
Q
--
Q
-
R
P
T
R
P
E
D
L
V
G
K
R
I
M
V
L
K
G
S
S
H
A
E
Q
L
A
E
L
K
K
Q
Y
P
E
L
K
Y
----
E
E
-
S
D
A
-
V
E
V
V
D
L
L
R
M
V
D
V
G
D
I
D
L
T
L
V
D
---
S
-
N
E
L
-
A
M
---
N
-
Q
V
-
Y
-
F
--
P
N
V
---
R
V
A
F
D
F
---
G
E
A
R
G
L
A
W
-
A
L
P
G
G
D
--
D
D
S
L
M
N
E
V
N
A
F
L
D
Q
A
K
K
E
G
L
L
Q
R
L
K
D
R
Y
Y
G
-----
H
V
D
V
LG
Y
V
G
A
Y
T
F
A
Q
H
L
Q
Q
RLPRY
E
S
H
F
K
Q
S
G
K
Q
L
DTD
W
R
L
L
A
A
I
G
Y
Q
E
SLWQPGATSKTGVRGLMMLT
N
R
T
A
Q
A
M
GVSNRLD
P
K
Q
S
I
Q
G
G
S
K
Y
F
V
Q
I
R
S
E
LPESIKE
P
D
R
S
W
F
A
L
A
A
Y
N
IG
G
A
H
L
E
D
A
R
K
M
A
E
K
E
GLNPNK
W
L
D
V
K
K
M
LPRLAQKQWYAKTRYGYAR
G
G
E
T
V
H
F
V
Q
N
V
R
R
Y
Y
D
I
L
T
W
V
T
Q
P
Q
41
HHSearch
68.82
23%
-79
* C1 *
2PYY
1
?
A:
[4-223]
-------------------------------
P
L
L
V
A
T
-
R
V
I
P
P
F
V
L
-
S
-
N
-----
L
S
G
F
S
I
D
L
W
R
S
I
A
T
Q
-
I
---
G
I
E
S
K
L
I
E
Y
S
S
-
V
P
E
L
I
S
A
I
K
-
D
N
K
V
N
L
G
I
A
A
I
S
I
-
T
A
E
R
E
Q
--
N
F
D
F
S
L
P
I
F
A
S
-
G
L
Q
I
---
M
V
R
N
--
G
--
D
-
I
-
R
S
I
D
D
L
P
G
K
V
V
A
T
T
A
G
S
T
A
A
T
Y
L
R
E
H
H
--------
I
S
V
L
E
V
-
P
-
K
---
I
E
E
A
Y
K
A
L
Q
T
K
K
A
D
A
V
V
F
D
A
P
V
L
-
L
F
Y
-
A
A
---
N
-
E
G
K
G
-
K
--
V
E
I
-----
V
G
S
I
----
L
-
R
E
E
S
Y
G
I
I
L
P
N
N
---
S
P
Y
R
K
P
I
N
Q
A
L
L
N
L
K
E
N
G
T
Y
Q
S
L
Y
D
K
W
F
D
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
68.44
20%
-81
- C1 -
1II5
1
?
A:
[3-226]
-----------------------------
A
M
A
L
K
V
G
V
V
-
G
N
P
P
F
V
F
-
Y
-
G
----
A
F
T
G
I
S
L
D
V
W
R
A
V
A
E
S
-
Q
---
K
W
N
S
E
Y
V
R
Q
N
S
-
I
S
A
G
I
T
A
V
A
-
E
G
E
L
D
I
L
I
G
P
I
S
V
-
T
P
E
R
A
A
IE
G
I
T
F
T
Q
P
Y
F
S
S
-
G
I
G
L
---
L
I
P
G
T
-
A
TP
L
-
F
-
R
S
V
G
D
L
K
N
K
E
V
A
V
V
R
D
T
T
A
V
D
W
A
N
F
Y
--------
Q
A
D
V
R
E
T
-
N
-
N
---
L
T
A
A
I
T
L
L
Q
K
K
Q
V
E
A
V
M
F
D
R
P
A
L
-
I
Y
Y
-
T
R
---
Q
-
N
P
N
L
-
N
--
L
E
V
-----
T
E
I
R
----
V
-
S
L
E
P
Y
G
F
V
L
K
E
N
---
S
P
L
Q
K
T
I
N
V
E
M
L
N
L
L
Y
S
R
V
I
A
E
F
T
E
R
W
L
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
68.23
25%
-58
- C1 -
1WDN
1
GLNH_ECOLI
A:
[4-223]
-------------------------------
K
L
V
V
A
T
D
T
A
F
V
P
F
E
F
-
K
-
Q
-
G
-
D
L
Y
V
G
F
D
V
D
L
W
A
A
I
A
K
E
-
L
---
K
L
D
Y
E
L
K
P
M
-
D
-
F
S
G
I
I
P
A
L
Q
-
T
K
N
V
D
L
A
L
A
G
I
T
I
-
T
D
E
R
K
K
--
A
I
D
F
S
D
G
Y
Y
K
S
-
G
L
L
V
---
M
V
K
A
N
N
N
--
D
-
V
-
K
S
V
K
D
L
D
G
K
V
V
A
V
K
S
G
T
G
S
V
D
Y
A
K
A
N
I
---
K
---
T
K
D
L
R
Q
F
-
P
-
N
---
I
D
N
A
Y
M
E
L
G
T
N
R
A
D
A
V
L
H
D
T
P
N
I
-
L
Y
F
-
I
K
---
T
-
A
G
N
G
-
Q
--
F
K
A
-----
V
G
D
S
----
L
-
E
A
Q
Q
Y
G
I
A
F
P
K
G
S
--
D
E
L
R
D
K
V
N
G
A
L
K
T
L
R
E
N
G
T
Y
N
E
I
Y
K
K
W
F
G
T
E
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
67.80
27%
-51
- C1 -
4KPT
13
?
A:
[29-247]
-----------------------------
T
V
--
K
I
A
S
D
S
S
Y
A
P
F
E
F
-
Q
-
N
G
Q
-
K
K
W
V
G
I
D
V
D
I
M
Q
E
V
A
K
I
-
N
---
D
W
K
L
E
M
S
Y
P
-
G
-
F
D
A
A
L
Q
N
L
K
-
A
G
Q
V
D
G
I
I
A
G
M
T
I
-
T
D
E
R
K
E
--
T
F
D
F
S
N
P
Y
Y
T
S
-
A
L
T
I
---
A
T
T
K
D
-
S
--
K
-
L
-
S
D
Y
S
D
L
K
G
K
A
V
----
G
A
K
N
G
T
A
A
Q
T
W
L
Q
E
N
Q
K
K
Y
G
Y
T
I
K
T
Y
-
S
D
G
-
V
H
M
F
A
A
L
---
S
S
G
N
I
A
G
A
M
D
E
V
P
V
I
-
S
Y
A
-
M
K
Q
GQ
D
-
L
A
-
M
-
N
--
F
P
S
---
I
S
L
P
G
G
Y
G
-----------
F
A
V
M
K
G
K
N
S
T
L
V
D
G
F
N
K
A
L
A
E
M
K
S
N
G
D
Y
D
K
I
L
K
K
Y
G
I
T
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
66.61
31%
-33
- C1 -
2YLN
10
?
A:
[59-279]
--------------------------------
V
T
V
G
T
E
G
T
Y
A
P
F
T
Y
-
H
D
K
-
D
-
G
K
L
T
G
Y
D
V
E
V
T
R
A
V
A
E
K
-
L
---
G
V
K
V
E
F
K
E
T
-
Q
-
W
D
S
M
M
A
G
L
K
-
A
G
R
F
D
V
V
A
N
Q
V
G
L
T
S
P
E
R
Q
A
--
T
F
D
K
S
E
P
Y
S
W
S
-
G
A
V
L
---
V
A
H
N
D
-
S
--
N
-
I
-
K
S
I
A
D
--------
I
K
G
V
K
T
A
Q
S
L
---
T
S
N
Y
G
E
K
A
K
A
A
G
A
Q
L
-
V
P
V
-
D
G
L
A
Q
S
L
T
L
I
E
Q
K
R
A
D
A
T
L
N
D
E
L
A
V
L
D
Y
L
-
K
K
---
N
-
P
N
-
A
-
G
--
V
K
I
VWS
A
P
A
D
E
K
V
G
-
S
G
--------
L
I
V
N
K
G
N
D
E
A
V
A
K
F
-
S
T
A
I
N
E
L
K
A
D
G
T
L
K
K
L
G
E
Q
F
F
G
K
D
I
S
V
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
66.07
27%
-45
- C1 -
2O1M
3
TCYK_BACSU
A:
[36-245]
-----------------------------------------------------
G
D
L
T
G
Y
D
V
E
L
I
K
E
L
D
K
R
L
P
---
H
Y
K
F
T
F
K
T
M
-
E
-
F
S
N
L
L
V
S
L
G
-
Q
H
K
V
D
I
V
A
H
Q
M
E
K
-
S
K
E
R
E
K
--
K
F
L
F
-
N
K
V
A
Y
N
-
H
F
P
L
K
IT
V
L
Q
N
N
-
D
--
T
-
I
-
R
G
I
E
D
L
K
G
K
R
V
I
T
S
A
T
S
N
G
A
L
V
L
K
K
W
N
E
D
--
N
G
R
P
F
E
I
A
Y
E
-
G
---
Q
G
A
N
E
T
A
N
Q
L
K
S
G
R
A
D
A
T
I
S
T
P
F
A
V
-
D
F
Q
-
N
K
---------------
T
---
S
T
I
K
E
K
T
V
-
G
N
V
L
S
N
A
K
-
V
Y
F
M
F
N
K
N
E
Q
T
L
S
D
D
I
D
K
A
L
Q
E
I
I
D
D
G
T
L
K
R
L
S
L
K
W
L
G
D
D
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
65.83
21%
-52
- C1 -
2YJP
10
?
A:
[45-282]
--------------------AAT
V
A
A
I
K
E
K
G
V
I
R
I
G
V
F
G
D
K
P
P
F
G
Y
-
V
-
D
A
N
-
G
K
N
Q
G
F
D
V
E
I
A
K
D
L
A
K
D
-
L
LGS
P
D
K
V
E
F
V
L
T
-
E
-
A
A
N
R
V
E
Y
V
R
-
S
G
K
V
D
L
I
L
A
N
F
T
Q
-
T
P
E
R
A
E
--
A
V
D
F
A
D
P
Y
M
K
V
-
A
L
G
V
---
V
S
P
K
N
-
K
--
P
-
I
-
T
D
M
A
Q
L
K
D
Q
T
L
L
V
N
K
G
T
T
A
D
A
F
F
T
K
S
H
---
P
---
E
V
K
L
L
K
F
-
D
-
Q
---
N
T
E
T
F
D
A
L
K
D
G
R
G
V
A
L
A
H
D
N
A
L
L
-
W
A
W
-
A
K
---
E
-
N
P
---
N
--
F
E
V
-----
A
I
G
N
----
L
G
P
A
E
F
I
A
P
A
V
Q
K
G
N
--
A
D
L
L
N
W
V
N
G
E
I
A
A
M
K
K
D
G
R
L
K
A
A
Y
E
K
T
L
L
P
V
Y
G
E
K
V
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
64.85
22%
-50
- C1 -
1LST
1
ARGT_SALTY
A:
[2-234]
----------------------------
L
P
Q
T
V
R
I
G
T
D
T
T
Y
A
P
F
S
S
-
K
-
D
A
K
-
G
E
F
I
G
F
D
I
D
L
G
N
E
M
C
K
R
-
M
---
Q
V
K
C
T
W
V
A
S
-
D
-
F
D
A
L
I
P
S
L
K
-
A
K
K
I
D
A
I
I
S
S
L
S
I
-
T
D
K
R
Q
Q
--
E
I
A
F
S
D
K
L
Y
A
A
-
D
S
R
L
---
I
A
A
K
G
-
S
P-
I
-
Q
-
P
T
L
E
S
L
K
G
K
H
V
G
V
L
Q
G
S
T
Q
E
A
Y
A
N
D
N
W
R
T
-
K
---
G
V
D
V
V
A
Y
-
A
-
N
---
Q
D
L
I
Y
S
D
L
T
A
G
R
L
D
A
A
L
Q
D
E
V
A
A
-
S
E
G
F
L
K
---
Q
-
P
A
G
K
-
E
--
Y
A
F
-----
A
G
P
S
V
K
D
K
K
Y
F
G
D
G
T
G
V
G
L
R
K
D
D
--
T
E
L
K
A
A
F
D
K
A
L
T
E
L
R
Q
D
G
T
Y
D
K
M
A
K
K
Y
F
D
F
N
V
Y
G
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
64.45
29%
-60
- C1 -
4GVO
3
?
A:
[27-238]
-------------------------------------------------
E
-
N
-
G
K
L
T
G
Y
D
V
E
L
V
K
E
I
D
K
R
L
P
---
G
Y
K
F
K
F
K
T
M
-
D
-
F
S
N
L
L
V
S
L
G
-
A
G
K
V
D
I
V
A
H
Q
M
E
K
-
S
K
E
R
E
K
--
K
F
L
F
N
D
-
V
A
Y
N
-
N
F
P
L
Q
LT
V
L
D
S
N
-
N
--
S
-
I
-
N
S
T
K
D
L
A
G
K
R
V
I
T
S
A
T
S
N
G
A
L
V
L
K
K
I
N
E
E
Q
G
N
N
--
F
E
I
A
Y
E
G
Q
G
S
-
N
D
T
A
N
Q
L
K
---
T
G
R
A
D
A
T
I
S
T
P
F
A
V
-
D
F
Q
-
N
K
---
T
-
S
A
-
I
-
K
--
E
K
V
---
V
---
G
D
V
L
-
S
N
--
A
K
V
Y
-
F
M
L
G
K
D
E
--
T
K
L
S
K
K
V
D
E
A
L
Q
S
I
I
D
D
G
T
L
K
K
L
S
E
K
W
L
G
A
D
Y
S
K
E
Q
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
64.01
25%
-65
- C1 -
2PVU
3
?
A:
[38-265]
--------------------------
G
A
T
K
K
K
V
V
V
G
T
D
A
A
F
A
P
F
E
Y
-
M
-
Q
-
K
-
G
K
I
V
G
F
D
V
D
L
L
D
A
V
M
K
A
-
A
---
G
L
D
Y
E
L
K
N
I
-
G
-
W
D
P
L
F
A
S
L
Q
-
S
K
E
V
D
M
G
I
S
G
I
T
I
-
T
D
E
R
K
Q
--
S
Y
D
F
S
D
P
Y
F
E
A
-
T
Q
V
I
---
L
V
K
Q
G
-
S
--
P
-
V
-
K
N
A
L
D
L
K
G
K
T
I
G
V
Q
N
A
T
T
G
Q
E
A
A
E
K
L
F
G
K
-----
G
P
H
I
K
K
F
-
E
-
T
---
T
V
V
A
I
M
E
L
L
N
G
G
V
D
A
V
I
T
D
N
A
V
A
-
N
E
Y
-
V
K
---
N
-
N
P
N
K
-
K
--
L
Q
V
-----
I
E
D
P
K
---
N
F
A
S
E
Y
Y
G
M
I
F
P
K
-
N
--
S
E
L
K
A
K
V
D
E
A
L
K
N
V
I
N
S
G
K
Y
T
E
I
Y
K
K
W
F
G
K
E
P
K
L
D
R
L
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------