@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0300: (2015-11-30 )
MQKFKERFDTLSDAILAIAMTILVLEIKTPATMGDIGDFTRNIGLFIVSFVVVFNFWYERAQNSLDAQKTNDEIIALDIIEHLGICLIPLFTKFMISFENHNFAVMAYGLLTLLVGLTSDIIRIRLASYDLVTIPSELKERVIKVMTTFAIRSVVVRFIIIILAYFLPEVGIFAYLVIPLFMFWRRSRAGKYYAKKGIEAPSYIKLFIQIGERAPEDFTNSSSGIGGVKRLYKK
Atome Classification :
(20 SA)
---------------.----........10-..-------------......20........30-----------.........40........50-----------........60........70........80.....---------------...90........---100.......110-....--....120..-....-------.130.-----......140....--...150....-----...160....--...170--.........180.......190-........200.......210...------------.-...--220.......230---....-----------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------M----
Q
K
F
K
E
R
F
D
T
L
-
S
D
-------------
A
I
L
A
I
A
M
T
I
L
V
L
E
IKTP------------ATMG
D
I
G
D
F
T
R
N
I
G
L
F
I
V
S
F
V
-----------
V
V
F
N
F
W
Y
E
R
A
QNSLDAQKTND
E
I
I
A
L
D
I
I
E
HL
G
I
C
---------------
L
I
P
L
F
T
K
F
M
ISFE---NH
N
F
A
V
M
A
Y
G
L
L
--
T
L
L
V
--
G
L
T
S
D
I
I
R
I
-
R
LAS-------Y
D
L
V
T-----
I
P
S
E
L
K
E
R
V
I
K
V
M
--
T
T
F
A
I
R
S
V
V
V
-----
R
F
I
I
I
I
L
A
Y
F
--LP
E
V
----
G
I
F
A
Y
L
V
I
P
L
F
M
F
W
R
RSRAG
K
--
Y
Y
A
KKGIEA
P
S
Y
I
K
L
F
I
Q
I
GERAP------------E-DFT--NSSSG
I
G
G
V
K
R
-----
L
YKK-----------------------
30
Fugue
86.88
18%
-132
- C5 -
4TXD
1
?
A:
[21-369]
------KRD
V
L
A
E
L
G
L
----
G
D
L
R
P
Y
L
R
S
I
-
G
D
KDRIFPKA
H
R
I
E
V
V
F
L
V
R
A
A
N
Y
L
L
L
R
T
E
G
A
------------
G
T
I
-
N
M
T
T
L
E
Y
S
G
G
A
M
E
V
P
V
I
Q
P
Q
K
L
M
A
V
T
R
R
Q
M
L
Q
L
L
R
E
Y
R
D
S
L
D
E
V
S
K
R
W
L
V
Q
E
V
I
G
K
A
K
D
L
G
F
K
KVSEE
W
N
C
T
IQGMDG
F
C
P
H
C
T
I
F
G
A
A
L
T
EQH
N
E
K
F
G
G
L
S
I
G
I
K
--
T
R
V
R
F
D
P
A
F
A
T
Q
R
R
I
-
T
P
E
T
-------
H
N
K
V
T
E
GH
L
S
M
T
G
Q
A
L
F
S
E
V
H
V
E
P
G
T
V
F
I
G
R
A
E
L
V
DLT
E
P
E
L
V
A
T
L
Y
S
L
A
T
-
L
R
E
L
G
G
RS
G
I
Y
G
T
V
R
V
E
I
L
G
V
K
A
G
K
Y
A
S
T
T
A
Y
D
L
A
A
E
N
A
G
K
G
Y
E
E
V
K
K
N
L
K
E
R
L
E
------------
K
L
G
F
T
P
V
D
N
S
K
L
L
A
A
V
D
H
KDPNG
L
F
K
D
L
W
R
S
S
I
D
F
A
E
K
M
V
K
W
V
E
E
L
KGGG
29
Fugue
69.10
13%
-44
- C6 -
1F1M
1
?
A:
[3-164]
------------------------
P
N
L
T
E
I
-
S
K
-------------
K
I
T
E
S
N
A
V
V
L
A
V
K
-
E
V
E
------------
T
L
L
T
S
I
D
E
L
A
K
A
I
G
K
K
I
-----------------------
K
S
D
V
S
L
D
N
E
A
D
H
N
---------------------------------
G
S
L
M
S
G
A
Y
L
---
I
S
T
L
I
T
K
K
I
S
A
I
--
K
D
S
G
--
E
L
K
A
E
I
E
K
A
-
K
K
C
S
-------
E
E
F
T
A
-----
K
L
K
G
E
H
T
D
L
G
K
E
G
--
V
T
D
D
N
A
K
K
A
I
-----
L
------------------------------------
K
T
N
N
--
D
K
T
K
G
A
D
E
L
E
K
L
F
E
S
V
K
N
L
S
K
A
A
K
------------
E
-
M
L
T
--
N
S
V
K
E
L
T
S
P
----------------------------------
24
Fugue
67.31
12%
-100
- C6 -
3IBP
1
A:
[11-293]
S
V
S
N
A
R
E
E
R
M
A
L
R
Q
E
Q
----
E
Q
L
Q
S
R
I
Q
S
L
M
Q
R
-------------
A
P
V
W
L
A
A
Q
N
S
L
N
Q
L
S
E
Q
C
GEEFTS
S
Q
D
V
T
E
Y
L
Q
Q
L
L
E
R
E
R
E
A
I
V
E
R
D
E
V
G
-----------
A
R
K
N
A
V
D
E
E
I
E
R
L
S
Q
P
G
G
S
E
D
Q
R
L
N
A
L
A
E
R
F
G
G
V
L
---------------
L
S
E
I
Y
D
D
--
V
S
L
E
---
D
A
P
Y
F
S
A
L
Y
G
P
S
RH
A
I
V
V
--
P
D
L
S
Q
V
T
E
H
-
L
E
G
L
TDCPE
D
L
Y
L
I
E
G
-----
D
P
Q
S
F
D
D
S
V
F
S
V
D
--
E
L
E
K
A
V
V
V
K
I
-----
A
D
R
Q
W
R
Y
S
R
F
PE
V
P
L
F
----
G
R
A
A
R
E
S
R
I
E
S
L
H
A
E
R
E
V
L
S
E
--
R
F
A
T
L
S
F
D
V
Q
K
T
Q
R
L
H
Q
A
F
S
R
F
I
G
SHLAVAFESD
P
E
A
-
E
I
R
--
Q
L
N
S
R
R
V
E
L
E
R
-----
A
L
S
N
-----------------------
25
Fugue
62.44
17%
-155
- C6 -
2B99
4
RISC_METJA
A:
[2-147]
--------------------------------------------------------------------------------------
T
K
K
V
G
I
V
D
T
T
-----------
F
A
R
V
D
M
A
S
I
A
I
K
K
L
K
E
L
S
P
N
I
K
I
I
R
K
T
V
---
P
G
I
K
---------------
D
L
P
V
A
C
K
K
L
L
E
E
E
---
G
C
D
-
I
V
M
A
L
G
M
------
P
--
G
K
A
E
K
D
K
V
C
A
H
E
A
S
-------
L
G
L
M
L
-----
A
Q
L
M
T
N
K
H
I
I
E
V
F
--
V
H
E
D
E
A
K
D
D
K
-----
E
L
D
W
L
A
K
R
R
A
--
E
E
H
A
----
E
N
V
Y
Y
L
L
F
K
P
E
Y
L
T
R
M
A
G
K
G
L
--
R
Q
G
-----------------------------------------------------------------------------------
10
PsiBlast_CBE
53.37
35%
-163
- C6 -
3E7J
1
HEPB_PEDHD
B:
[104-144]
---------------------------------------------------
A
I
T
S
I
I
D
T
L
E
T
-------------
A
T
F
K
P
A
G
D
I
S
R
G
I
G
L
F
M
V
T
G
A
-----------
I
V
Y
D
W
C
Y
D
Q
L
K
P
E
E
K
T
R
F
V
K
A
F
V
R
L
A
K
M
L
E
C
G
Y
P
P
---------------
V
K
D
K
S
I
V
G
A
A
S
E
W
---
M
I
M
R
D
L
L
S
V
G
I
A
--
I
Y
D
E
--
F
P
E
M
Y
N
L
A
A
-
G
R
F
F
-------
K
E
H
L
V
-----
A
R
N
W
F
Y
P
S
H
N
Y
H
Q
--
G
M
S
A
L
N
V
R
F
T
-----
N
D
L
F
A
L
W
I
L
D
--
R
M
G
A
----
G
N
V
F
N
P
G
Q
Q
F
I
L
Y
D
A
I
Y
K
R
R
P
--
D
G
Q
I
L
A
G
G
D
V
D
Y
S
R
K
K
P
K
Y
Y
T
M
P
A
------------
L
-
L
A
G
--
S
Y
Y
K
D
E
Y
L
N
Y
E
-----
F
L
K
D
-----------------------
4
PsiBlast_PDB
53.25
35%
-171
- C6 -
2FUT
1
HEPB_PEDHD
A:
[103-143]
---------------------------------------------------
A
I
T
S
I
I
D
T
L
E
T
-------------
A
T
F
K
P
A
G
D
I
S
R
G
I
G
L
F
M
V
T
G
A
-----------
I
V
Y
D
W
C
Y
D
Q
L
K
P
E
E
K
T
R
F
V
K
A
F
V
R
L
A
K
M
L
E
C
G
Y
P
P
---------------
V
K
D
K
S
I
V
G
H
A
S
E
W
---
M
I
M
R
D
L
L
S
V
G
I
A
--
I
Y
D
E
--
F
P
E
M
Y
N
L
A
A
-
G
R
F
F
-------
K
E
H
L
V
-----
A
R
N
W
F
Y
P
S
H
N
Y
H
Q
--
G
M
S
Y
L
N
V
R
F
T
-----
N
D
L
F
A
L
W
I
L
D
--
R
M
G
A
----
G
N
V
F
N
P
G
Q
Q
F
I
L
Y
D
A
I
Y
K
R
R
P
--
D
G
Q
I
L
A
G
G
D
V
D
Y
S
R
K
K
P
K
Y
Y
T
M
P
A
------------
L
-
L
A
G
--
S
Y
Y
K
D
E
Y
L
N
Y
E
-----
F
L
K
D
-----------------------
1
PsiBlast_PDB
53.24
35%
-167
- C6 -
3E7J
1
HEPB_PEDHD
A:
[104-144]
---------------------------------------------------
A
I
T
S
I
I
D
T
L
E
T
-------------
A
T
F
K
P
A
G
D
I
S
R
G
I
G
L
F
M
V
T
G
A
-----------
I
V
Y
D
W
C
Y
D
Q
L
K
P
E
E
K
T
R
F
V
K
A
F
V
R
L
A
K
M
L
E
C
G
Y
P
P
---------------
V
K
D
K
S
I
V
G
A
A
S
E
W
---
M
I
M
R
D
L
L
S
V
G
I
A
--
I
Y
D
E
--
F
P
E
M
Y
N
L
A
A
-
G
R
F
F
-------
K
E
H
L
V
-----
A
R
N
W
F
Y
P
S
H
N
Y
H
Q
--
G
M
S
A
L
N
V
R
F
T
-----
N
D
L
F
A
L
W
I
L
D
--
R
M
G
A
----
G
N
V
F
N
P
G
Q
Q
F
I
L
Y
D
A
I
Y
K
R
R
P
--
D
G
Q
I
L
A
G
G
D
V
D
Y
S
R
K
K
P
K
Y
Y
T
M
P
A
------------
L
-
L
A
G
--
S
Y
Y
K
D
E
Y
L
N
Y
E
-----
F
L
K
D
-----------------------
2
PsiBlast_PDB
47.67
35%
-69
- C6 -
3E80
3
HEPB_PEDHD
A:
[106-144]
---------------------------------------------------
A
I
T
S
I
I
D
T
L
E
T
-------------
A
T
F
K
P
A
G
D
I
S
R
G
I
G
L
F
M
V
T
G
A
-----------
I
V
Y
D
W
C
Y
D
Q
L
K
P
E
E
K
T
R
F
V
K
A
F
V
R
L
A
K
M
L
E
C
G
Y
P
P
---------------
V
K
D
K
S
I
V
G
H
A
S
E
W
---
M
I
M
R
D
L
L
S
V
G
I
A
--
I
Y
D
E
--
F
P
E
M
Y
N
L
A
A
-
G
R
F
F
-------
K
E
H
L
V
-----
A
R
N
W
F
Y
P
S
H
N
Y
H
Q
--
G
M
S
Y
L
N
V
R
F
T
-----
N
D
L
F
A
L
W
I
L
D
--
R
M
G
A
----
G
N
V
F
N
P
G
Q
Q
F
I
L
Y
D
A
I
Y
K
R
R
P
--
D
G
Q
I
L
A
G
G
D
V
D
Y
S
R
K
K
P
K
Y
Y
T
M
P
A
------------
L
-
L
A
G
--
S
Y
Y
K
D
E
Y
L
N
Y
E
-----
F
L
K
D
-----------------------
7
PsiBlast_PDB
47.27
29%
48
- C7 -
1PO0
-
FECA_ECOLI
A:
[553-596]
---------------------------------------------------------------------------
G
T
R
Y
D
D
G
A
L
T
A
E
M
G
L
F
L
I
N
F
----------------------
N
N
Q
Y
D
S
N
Q
T
N
D
T
V
T
A
R
G
K
T
R
H
T
G
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
47.20
29%
51
- C7 -
1PNZ
-
FECA_ECOLI
A:
[543-586]
---------------------------------------------------------------------------
G
T
R
Y
D
D
G
A
L
T
A
E
M
G
L
F
L
I
N
F
----------------------
N
N
Q
Y
D
S
N
Q
T
N
D
T
V
T
A
R
G
K
T
R
H
T
G
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
46.81
29%
55
* C7 *
1KMO
4
FECA_ECOLI
A:
[576-619]
---------------------------------------------------------------------------
G
T
R
Y
D
D
G
A
L
T
A
E
M
G
L
F
L
I
N
F
----------------------
N
N
Q
Y
D
S
N
Q
T
N
D
T
V
T
A
R
G
K
T
R
H
T
G
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_CBE
46.56
35%
-68
- C6 -
2FUQ
1
HEPB_PEDHD
B:
[104-142]
---------------------------------------------------
A
I
T
S
I
I
D
T
L
E
T
-------------
A
T
F
K
P
A
G
D
I
S
R
G
I
G
L
F
M
V
T
G
A
-----------
I
V
Y
D
W
C
Y
D
Q
L
K
P
E
E
K
T
R
F
V
K
A
F
V
R
L
A
K
M
L
E
C
G
Y
P
P
---------------
V
K
D
K
S
I
V
G
H
A
S
E
W
---
M
I
M
R
D
L
L
S
V
G
I
A
--
I
Y
D
E
--
F
P
E
M
Y
N
L
A
A
-
G
R
F
F
-------
K
E
H
L
V
-----
A
R
N
W
F
Y
P
S
H
N
Y
H
Q
--
G
M
S
Y
L
N
V
R
F
T
-----
N
D
L
F
A
L
W
I
L
D
--
R
M
G
A
----
G
N
V
F
N
P
G
Q
Q
F
I
L
Y
D
A
I
Y
K
R
R
P
--
D
G
Q
I
L
A
G
G
D
V
D
Y
S
R
K
K
P
K
Y
Y
T
M
P
A
------------
L
-
L
A
G
--
S
Y
Y
K
D
E
Y
L
N
Y
E
-----
F
L
K
D
-----------------------
12
PsiBlast_CBE
46.22
35%
-67
- C6 -
3E80
3
HEPB_PEDHD
B:
[106-144]
---------------------------------------------------
A
I
T
S
I
I
D
T
L
E
T
-------------
A
T
F
K
P
A
G
D
I
S
R
G
I
G
L
F
M
V
T
G
A
-----------
I
V
Y
D
W
C
Y
D
Q
L
K
P
E
E
K
T
R
F
V
K
A
F
V
R
L
A
K
M
L
E
C
G
Y
P
P
---------------
V
K
D
K
S
I
V
G
H
A
S
E
W
---
M
I
M
R
D
L
L
S
V
G
I
A
--
I
Y
D
E
--
F
P
E
M
Y
N
L
A
A
-
G
R
F
F
-------
K
E
H
L
V
-----
A
R
N
W
F
Y
P
S
H
N
Y
H
Q
--
G
M
S
Y
L
N
V
R
F
T
-----
N
D
L
F
A
L
W
I
L
D
--
R
M
G
A
----
G
N
V
F
N
P
G
Q
Q
F
I
L
Y
D
A
I
Y
K
R
R
P
--
D
G
Q
I
L
A
G
G
D
V
D
Y
S
R
K
K
P
K
Y
Y
T
M
P
A
------------
L
-
L
A
G
--
S
Y
Y
K
D
E
Y
L
N
Y
E
-----
F
L
K
D
-----------------------
9
PsiBlast_PDB
46.02
29%
7
- C7 -
1KMP
5
FECA_ECOLI
A:
[576-619]
---------------------------------------------------------------------------
G
T
R
Y
D
D
G
A
L
T
A
E
M
G
L
F
L
I
N
F
----------------------
N
N
Q
Y
D
S
N
Q
T
N
D
T
V
T
A
R
G
K
T
R
H
T
G
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_CBE
45.91
35%
-55
- C6 -
3E80
3
HEPB_PEDHD
C:
[106-144]
---------------------------------------------------
A
I
T
S
I
I
D
T
L
E
T
-------------
A
T
F
K
P
A
G
D
I
S
R
G
I
G
L
F
M
V
T
G
A
-----------
I
V
Y
D
W
C
Y
D
Q
L
K
P
E
E
K
T
R
F
V
K
A
F
V
R
L
A
K
M
L
E
C
G
Y
P
P
---------------
V
K
D
K
S
I
V
G
H
A
S
E
W
---
M
I
M
R
D
L
L
S
V
G
I
A
--
I
Y
D
E
--
F
P
E
M
Y
N
L
A
A
-
G
R
F
F
-------
K
E
H
L
V
-----
A
R
N
W
F
Y
P
S
H
N
Y
H
Q
--
G
M
S
Y
L
N
V
R
F
T
-----
N
D
L
F
A
L
W
I
L
D
--
R
M
G
A
----
G
N
V
F
N
P
G
Q
Q
F
I
L
Y
D
A
I
Y
K
R
R
P
--
D
G
Q
I
L
A
G
G
D
V
D
Y
S
R
K
K
P
K
Y
Y
T
M
P
A
------------
L
-
L
A
G
--
S
Y
Y
K
D
E
Y
L
N
Y
E
-----
F
L
K
D
-----------------------
3
PsiBlast_PDB
45.68
35%
-65
- C6 -
2FUQ
2
HEPB_PEDHD
A:
[104-142]
---------------------------------------------------
A
I
T
S
I
I
D
T
L
E
T
-------------
A
T
F
K
P
A
G
D
I
S
R
G
I
G
L
F
M
V
T
G
A
-----------
I
V
Y
D
W
C
Y
D
Q
L
K
P
E
E
K
T
R
F
V
K
A
F
V
R
L
A
K
M
L
E
C
G
Y
P
P
---------------
V
K
D
K
S
I
V
G
H
A
S
E
W
---
M
I
M
R
D
L
L
S
V
G
I
A
--
I
Y
D
E
--
F
P
E
M
Y
N
L
A
A
-
G
R
F
F
-------
K
E
H
L
V
-----
A
R
N
W
F
Y
P
S
H
N
Y
H
Q
--
G
M
S
Y
L
N
V
R
F
T
-----
N
D
L
F
A
L
W
I
L
D
--
R
M
G
A
----
G
N
V
F
N
P
G
Q
Q
F
I
L
Y
D
A
I
Y
K
R
R
P
--
D
G
Q
I
L
A
G
G
D
V
D
Y
S
R
K
K
P
K
Y
Y
T
M
P
A
------------
L
-
L
A
G
--
S
Y
Y
K
D
E
Y
L
N
Y
E
-----
F
L
K
D
-----------------------
8
PsiBlast_PDB
43.89
29%
14
- C7 -
1PO3
4
FECA_ECOLI
A:
[553-596]
---------------------------------------------------------------------------
G
T
R
Y
D
D
G
A
L
T
A
E
M
G
L
F
L
I
N
F
----------------------
N
N
Q
Y
D
S
N
Q
T
N
D
T
V
T
A
R
G
K
T
R
H
T
G
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
41.86
21%
42
- C6 -
1HGV
-
CAPSD_BPH75
A:
[1-46]
---------------
M
DFNP
S
E
V
A
S
Q
V
T
N
Y
-
I
Q
-------------
A
I
A
A
A
G
V
G
V
L
A
L
A
I
G
L
S
------------
A
A
W
K
Y
A
K
R
F
L
K
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
37.77
50%
696
- C2 -
1JEG
-
B:
[14-23]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
T
P
------------
E
-
S
F
I
--
V
V
E
E
---------------------------------------
32
Fugue
36.69
33%
187
* C6 *
3PBP
-
NU159_YEAST
C:
[9-33]
-----------------------------------------------------
G
F
K
V
V
E
V
G
L
A
M
-----------
N
T
K
K
Q
I
G
D
F
F
K
N
L
N
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------