@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0329: (2015-11-30 )
MKFENIIYGIDGNVATIMLNRPDISNGFNIPMCQEIIDAIRLVSENKDVMFLVIEAQGPIFSIGGDLKVMKAAVESDDISSLTKIAELVNQISYDLLQLEKPVVMCVDGAVAGAAANIALAADFVIASKKSKFIQAFVGVGLAPDAGGLLLLSKSIGITRAVQLALTGESLSAEKAEALGIVYKLCESDKIGKIKDQLLKRLSRHSINSYQAIKSLAWEAAFKDWEQYKKLELQLQESLAFKQDFKEGVRAHADRRRPNFLGK
Atome Classification :
(20 SA)
........-.10.-........20........30........40........50.......-.60........70.-----.......80........90..-..-....100........110.......120.......130........140...-...-.150.......160......--.170.......180.....-..190.......200.......210..---.....220.....--.-.230-......--.240.......250.......260.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKF
E
N
I
I
Y
-GI-D-G
N
V
A
T
I
M
LNRPDISNGFN
I
P
M
C
Q
E
I
I
D
A
I
R
L
VSENK
D
V
M
F
L
V
I
EAQG-
P
I
F
SIGG
D
L
K
V
M
K
A
-----AVES
D
D
I
S
S
L
T
K
I
A
E
L
V
N
Q
I
S
-
Y
D
-
L
L
Q
LEK-
P
V
V
M
C
VDGAVAGAAA
N
I
A
L
A
A
D
F
V
IAS
K
K
-
S
K
F
I
Q
A
F
V
GVGLAPD-AG
G
-
L
L
L
L
SKSIG
I
T
R
A
V
Q
L
A
LTG--ESL
S
A
E
K
A
E
A
L
G
I
V
Y
K
L
CE-SDKI
G
K
I
K
D
Q
L
L
K
R
L
S
RHSI
N
S
Y
Q
A
I
K
---
S
L
A
W
E
A
A
F
K
D
W
E
Q
--
Y
-
K
K
L
E
-
L
Q
L
Q
E
S
--
L
A
F
K
Q
D
F
K
E
G
V
R
A
H
ADRRRPNFLGK
2
PsiBlast_PDB
93.88
35%
-106
- C1 -
2EJ5
-
?
A:
[4-258]
--
Y
E
T
I
R
Y
-
E
V
-
K
-
G
Q
V
A
W
L
T
L
N
R
P
D
Q
L
N
A
F
T
E
Q
M
N
A
E
V
T
K
A
L
K
Q
A
G
A
D
P
N
V
R
C
V
V
I
T
G
A
G
-
R
A
F
C
A
G
E
D
L
------------
D
H
G
D
V
L
R
-
S
R
Y
A
P
M
M
K
A
L
H
-
H
-----
L
E
K
-
P
V
V
A
A
V
N
G
A
A
A
G
A
G
M
S
L
A
L
A
C
D
F
R
L
L
S
E
K
-
A
S
F
A
P
A
F
I
H
V
G
L
V
P
D
-
A
G
H
-
L
Y
Y
L
P
R
L
V
G
R
A
K
A
L
E
L
A
V
L
G
--
E
K
V
T
A
E
E
A
A
A
L
G
L
A
T
K
V
I
P
L
S
D
W
E
E
E
V
K
-
Q
F
A
E
R
L
S
A
M
P
T
K
A
I
G
L
I
K
---
R
L
L
R
E
S
E
E
T
T
F
D
R
--
Y
-
L
E
R
E
-
A
E
C
Q
R
I
--
A
G
L
T
S
D
H
R
E
G
V
K
A
F
F
E
K
R
K
P
L
F
Q
G
N
3
PsiBlast_PDB
90.45
31%
-102
- C1 -
3P5M
1
?
A:
[13-255]
------------
D
-
G
A
V
L
R
I
R
L
D
R
P
E
K
L
N
A
V
D
T
P
M
L
E
E
L
S
V
H
I
R
D
A
E
A
D
E
S
V
R
A
V
L
L
T
G
A
G
-
R
A
F
C
S
G
G
D
L
---
D
T
---------------
A
G
A
A
D
A
A
N
R
V
V
-
R
A
-
I
T
S
L
P
K
-
P
V
I
A
G
V
H
G
A
A
V
G
F
G
C
S
L
A
L
A
C
D
L
V
V
A
A
P
A
-
S
Y
F
Q
L
A
F
T
R
V
G
L
M
P
D
-
G
G
A
-
S
A
L
L
P
L
L
I
G
R
A
R
T
S
R
M
A
M
T
A
--
E
K
I
S
A
A
T
A
F
E
W
G
M
I
S
H
I
T
S
-
A
D
E
Y
E
S
V
L
T
D
V
L
R
S
V
S
G
G
P
T
L
A
F
G
W
T
K
---
R
A
L
A
A
A
T
L
A
E
L
E
P
--
V
-
Q
A
I
E
-
A
E
G
Q
L
A
--
L
V
E
T
A
D
F
R
E
G
A
R
A
F
R
E
R
R
T
P
N
F
R
G
H
31
HHSearch
90.44
31%
-100
- C1 -
3P5M
1
?
A:
[4-255]
-
S
M
N
G
I
S
V
-
E
H
-
D
-
G
A
V
L
R
I
R
L
D
R
P
E
K
L
N
A
V
D
T
P
M
L
E
E
L
S
V
H
I
R
D
A
E
A
D
E
S
V
R
A
V
L
L
T
G
A
G
-
R
A
F
C
S
G
G
D
L
---
D
T
-----
A
--
G
--------
A
A
D
A
A
N
R
V
V
-
R
A
-
I
T
S
L
P
K
-
P
V
I
A
G
V
H
G
A
A
V
G
F
G
C
S
L
A
L
A
C
D
L
V
V
A
A
P
A
-
S
Y
F
Q
L
A
F
T
R
V
G
L
M
P
D
-
G
G
A
-
S
A
L
L
P
L
L
I
G
R
A
R
T
S
R
M
A
M
T
A
--
E
K
I
S
A
A
T
A
F
E
W
G
M
I
S
H
I
T
S
-
A
D
E
Y
E
S
V
L
T
D
V
L
R
S
V
S
G
G
P
T
L
A
F
G
W
T
K
---
R
A
L
A
A
----
A
T
L
A
E
L
E
P
V
Q
A
I
E
A
E
G
Q
L
A
--
L
V
E
T
A
D
F
R
E
G
A
R
A
F
R
E
R
R
T
P
N
F
R
G
H
23
HHSearch
89.83
35%
-99
- C1 -
2EJ5
-
?
A:
[4-259]
--
Y
E
T
I
R
Y
-
E
V
-
K
-
G
Q
V
A
W
L
T
L
N
R
P
D
Q
L
N
A
F
T
E
Q
M
N
A
E
V
T
K
A
L
K
Q
A
G
A
D
P
N
V
R
C
V
V
I
T
G
A
G
-
R
A
F
C
A
G
E
D
L
--------------
D
H
---
G
D
V
L
R
S
R
Y
A
P
M
M
-
K
A
-
L
H
H
L
E
K
-
P
V
V
A
A
V
N
G
A
A
A
G
A
G
M
S
L
A
L
A
C
D
F
R
L
L
S
E
K
-
A
S
F
A
P
A
F
I
H
V
G
L
V
P
D
-
A
G
H
-
L
Y
Y
L
P
R
L
V
G
R
A
K
A
L
E
L
A
V
L
G
--
E
K
V
T
A
E
E
A
A
A
L
G
L
A
T
K
V
I
P
-
L
S
D
W
E
E
E
V
K
Q
F
A
E
R
L
S
A
M
P
T
K
A
I
G
L
I
K
---
R
L
L
R
E
----
S
E
E
T
T
F
D
R
Y
L
E
R
E
A
E
C
Q
R
I
--
A
G
L
T
S
D
H
R
E
G
V
K
A
F
F
E
K
R
K
P
L
F
Q
G
N
35
HHSearch
88.70
27%
-91
- C1 -
3G64
4
?
A:
[15-277]
-
E
W
R
H
L
R
V
-
E
I
-
T
-
D
G
V
A
T
V
T
L
A
R
P
D
K
L
N
A
L
T
F
E
A
Y
A
D
L
R
D
L
L
A
E
L
S
R
R
R
A
V
R
A
L
V
L
A
G
E
G
-
R
G
F
C
S
G
G
D
V
D
E
I
I
G
-----
A
T
L
S
M
D
T
A
R
L
L
D
F
N
R
M
T
G
Q
V
V
-
R
A
-
V
R
E
C
P
F
-
P
V
I
A
A
L
H
G
V
A
A
G
A
G
A
V
L
A
L
A
A
D
F
R
V
A
D
P
S
-
T
R
F
A
F
L
F
T
R
V
G
L
S
G
G
D
M
G
A
-
A
Y
L
L
P
R
V
V
G
L
G
H
A
T
R
L
L
M
L
G
--
D
T
V
R
A
P
E
A
E
R
I
G
L
I
S
E
L
T
E
-
E
G
R
A
D
E
A
A
R
T
L
A
R
R
L
A
D
G
P
A
L
A
H
A
Q
T
K
---
A
L
L
T
A
----
E
L
D
M
P
L
A
A
A
V
E
L
D
A
S
T
Q
A
L
--
L
M
T
G
E
D
Y
A
E
F
H
A
A
F
T
E
K
R
P
P
K
W
Q
G
R
22
PsiBlast_CBE
87.16
31%
-99
- C1 -
3P5M
1
?
D:
[13-255]
------------
D
-
G
A
V
L
R
I
R
L
D
R
P
E
K
L
N
A
V
D
T
P
M
L
E
E
L
S
V
H
I
R
D
A
E
A
D
E
S
V
R
A
V
L
L
T
G
A
G
-
R
A
F
C
S
G
G
D
----
D
T
---------------
A
G
A
A
D
A
A
N
R
V
V
-
R
A
-
I
T
S
L
P
K
-
P
V
I
A
G
V
H
G
A
A
V
G
F
G
C
S
L
A
L
A
C
D
L
V
V
A
A
P
A
-
S
Y
F
Q
L
A
F
T
R
V
G
L
M
P
D
-
G
G
A
-
S
A
L
L
P
L
L
I
G
R
A
R
T
S
R
M
A
M
T
A
--
E
K
I
S
A
A
T
A
F
E
W
G
M
I
S
H
I
T
S
-
A
D
E
Y
E
S
V
L
T
D
V
L
R
S
V
S
G
G
P
T
L
A
F
G
W
T
K
---
R
A
L
A
A
A
T
L
A
E
L
E
P
--
V
-
Q
A
I
E
-
A
E
G
Q
L
A
--
L
V
E
T
A
D
F
R
E
G
A
R
A
F
R
E
R
R
T
P
N
F
R
G
H
20
PsiBlast_PDB
86.17
25%
-99
- C1 -
3H81
5
ECHA8_MYCTU
A:
[23-275]
-
T
Y
E
T
I
L
V
-
E
R
-
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
D
L
T
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
-------------
A
V
R
T
-
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
-
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
-
M
G
G
-
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
--
R
T
M
D
A
A
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A
E
R
S
G
L
V
S
R
V
V
P
-
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
S
E
G
L
L
--
Y
-
E
R
----
R
L
F
H
S
--
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
H
R
21
PsiBlast_CBE
86.14
31%
-102
- C1 -
3P5M
1
?
E:
[13-255]
------------
D
-
G
A
V
L
R
I
R
L
D
R
P
E
K
L
N
A
V
D
T
P
M
L
E
E
L
S
V
H
I
R
D
A
E
A
D
E
S
V
R
A
V
L
L
T
G
A
G
-
R
A
F
C
S
G
G
---
G
G
D
T
---------------
A
G
A
A
D
A
A
N
R
V
V
-
R
A
-
I
T
S
L
P
K
-
P
V
I
A
G
V
H
G
A
A
V
G
F
G
C
S
L
A
L
A
C
D
L
V
V
A
A
P
A
-
S
Y
F
Q
L
A
F
T
R
V
G
L
M
P
D
-
G
G
A
-
S
A
L
L
P
L
L
I
G
R
A
R
T
S
R
M
A
M
T
A
--
E
K
I
S
A
A
T
A
F
E
W
G
M
I
S
H
I
T
S
-
A
D
E
Y
E
S
V
L
T
D
V
L
R
S
V
S
G
G
P
T
L
A
F
G
W
T
K
---
R
A
L
A
A
A
T
L
A
E
L
E
P
--
V
-
Q
A
I
E
-
A
E
G
Q
L
A
--
L
V
E
T
A
D
F
R
E
G
A
R
A
F
R
E
R
R
T
P
N
F
R
G
H
11
PsiBlast_PDB
85.82
26%
-104
- C1 -
3TLF
3
?
A:
[10-271]
--
F
D
T
I
K
Y
-
E
V
-
D
-
G
H
T
A
T
I
T
L
N
R
P
D
A
L
N
A
L
S
P
H
M
I
T
E
L
R
A
A
Y
H
E
A
E
N
D
D
R
V
W
L
L
V
V
T
G
T
G
-
R
A
F
C
S
G
A
D
---------------
P
Y
L
S
T
Y
D
Q
W
-
E
A
P
Q
E
G
T
-
P
P
-
F
R
T
M
A
K
-
P
V
L
T
A
V
N
G
I
C
C
G
A
G
M
D
W
V
T
T
T
D
I
V
I
A
S
E
Q
-
A
T
F
F
D
P
H
V
S
I
G
L
V
---
A
G
R
E
L
V
R
V
S
R
V
L
P
R
S
I
A
L
R
M
A
L
M
G
KH
E
R
M
S
A
Q
R
A
Y
E
L
G
L
I
S
E
I
V
E
-
H
D
R
L
L
E
R
A
H
E
I
A
D
I
V
N
S
N
A
P
L
A
V
R
G
T
R
---
L
A
I
L
K
G
L
N
V
P
L
H
E
--
A
-
E
I
L
A
-
E
T
F
R
E
R
--
V
L
R
T
E
D
A
A
E
G
P
R
A
F
V
E
K
R
Q
P
N
W
Q
C
R
5
PsiBlast_PDB
85.81
30%
-98
- C1 -
2PBP
-
?
A:
[4-258]
--
F
V
S
I
A
A
-
R
Q
-
E
-
G
A
V
G
I
I
E
L
A
R
P
D
V
L
N
A
L
S
R
Q
M
V
A
E
I
V
A
A
V
E
A
F
D
R
N
E
K
V
R
V
I
V
L
T
G
R
G
-
R
A
F
A
A
G
A
D
I
Q
E
M
A
---------
K
D
D
P
I
R
L
----
E
W
L
N
Q
F
A
D
W
D
-
R
L
S
I
V
K
T
P
M
I
A
A
V
N
G
L
A
L
G
G
G
F
E
L
A
L
S
C
D
L
I
V
A
S
S
A
-
A
E
F
G
F
P
E
V
N
L
G
V
M
P
G
-
A
G
G
-
T
Q
R
L
T
K
L
I
G
P
K
R
A
L
E
W
L
W
T
G
--
A
R
M
S
A
K
E
A
E
Q
L
G
I
V
N
R
V
V
S
-
P
E
L
L
M
E
E
T
M
R
L
A
G
R
L
A
E
Q
P
P
L
A
L
R
L
I
K
---
E
A
V
Q
K
A
V
--
D
Y
P
L
--
Y
-
E
G
M
Q
-
F
E
R
K
N
F
Y
L
L
F
A
S
E
D
Q
K
E
G
M
A
A
F
L
E
K
R
K
P
R
F
Q
G
K
4
PsiBlast_PDB
85.78
31%
-116
- C1 -
4LK5
-
?
A:
[44-280]
---------------
G
V
F
S
V
T
I
N
R
P
D
S
L
N
S
L
T
V
P
V
I
T
G
I
A
D
A
M
E
Y
A
A
T
D
P
E
V
K
V
V
R
I
G
G
A
G
-
R
G
F
S
S
G
-------
A
-----
G
I
S
-----
P
P
D
E
I
I
L
E
I
N
R
L
V
-
R
A
-
I
A
A
L
P
H
-
P
V
V
A
V
V
Q
G
P
A
A
G
V
G
V
S
I
A
L
A
C
D
V
V
L
A
S
E
N
-
A
F
F
M
L
A
F
T
K
I
G
L
M
P
D
-
G
G
A
-
S
A
L
V
A
A
A
V
G
R
I
R
A
M
Q
M
A
L
L
P
--
E
R
L
P
A
A
E
A
L
A
W
G
L
V
T
A
V
Y
P
-
A
D
E
F
E
A
E
V
D
K
V
I
A
R
L
L
S
G
P
A
V
A
F
A
K
T
K
---
L
A
I
N
A
A
T
L
T
E
L
D
P
--
A
-
L
Q
R
E
-
F
D
G
Q
S
V
--
L
L
K
S
P
D
F
V
E
G
A
T
A
------------
8
PsiBlast_PDB
85.55
27%
-99
- C1 -
4MI2
-
?
A:
[9-267]
-----
V
A
Y
-
S
V
-
N
H
A
G
V
A
A
I
V
L
D
R
P
E
A
S
N
A
L
D
R
T
M
K
T
E
L
L
Q
A
L
L
A
A
G
G
D
P
A
V
R
A
V
V
M
S
A
A
G
-
K
N
F
C
V
G
Q
D
L
A
E
H
V
E
-----
A
L
R
D
D
P
A
H
A
M
D
T
V
R
E
H
Y
N
P
V
L
-
E
A
-
L
D
A
I
K
V
-
P
V
V
V
A
I
N
G
A
C
V
G
A
G
L
G
L
A
L
G
A
D
I
R
I
A
G
Q
R
-
A
K
F
G
T
A
F
T
G
I
G
L
A
A
D
-
S
A
L
-
S
A
S
L
P
R
L
I
G
A
S
R
A
T
A
M
F
L
L
G
--
D
T
I
D
A
P
T
A
H
T
W
G
L
V
H
E
V
V
D
-
E
G
S
P
A
D
V
A
N
S
V
A
G
R
L
A
G
G
P
T
A
A
F
S
E
V
K
---
E
L
L
R
R
N
A
V
A
P
L
G
D
--
V
-
L
E
R
E
-
A
S
A
Q
Q
R
--
L
G
A
S
R
D
H
S
A
A
V
E
A
F
L
A
K
D
K
P
V
F
V
G
R
16
PsiBlast_PDB
85.22
25%
-95
- C1 -
3Q0J
1
ECHA8_MYCTU
A:
[2-256]
M
T
Y
E
T
I
L
V
-
E
R
-
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
D
LT
F
A
D
A
F
T
A
D
F
F
A
T
W
G
K
L
A
-------------
A
V
R
T
-
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
-
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
-
M
G
G
-
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
--
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
-
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
S
E
G
L
L
--
Y
-
E
R
----
R
L
F
H
S
--
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
--
6
PsiBlast_PDB
84.81
30%
-96
- C1 -
2QQ3
1
?
A:
[4-258]
--
F
V
S
I
A
A
-
R
Q
-
E
-
G
A
V
G
I
I
E
L
A
R
P
D
V
L
N
A
L
S
R
Q
M
V
A
E
I
V
A
A
V
E
A
F
D
R
N
E
K
V
R
V
I
V
L
T
G
R
G
-
R
A
F
A
A
G
A
D
I
Q
E
M
A
---------
K
D
D
P
I
R
L
----
E
W
L
N
Q
F
A
D
W
D
-
R
L
S
I
V
K
T
P
M
I
A
A
V
N
G
L
A
L
G
G
G
F
E
L
A
L
S
C
D
L
I
V
A
S
S
A
-
A
E
F
G
F
P
E
V
N
L
G
V
M
P
G
-
A
G
G
-
T
Q
R
L
T
K
L
I
G
P
K
R
A
L
E
W
L
W
T
G
--
A
R
M
S
A
K
E
A
E
Q
L
G
I
V
N
R
V
V
S
-
P
E
L
L
M
E
E
T
M
R
L
A
G
R
L
A
E
Q
P
P
L
A
L
R
L
I
K
---
E
A
V
Q
K
A
V
--
D
Y
P
L
--
Y
-
E
G
M
Q
-
F
E
R
K
N
F
Y
L
L
F
A
S
E
D
Q
K
E
G
M
A
A
F
L
E
K
R
K
P
R
F
Q
G
K
17
PsiBlast_PDB
84.43
25%
-96
- C1 -
3PZK
2
ECHA8_MYCTU
A:
[2-255]
-
T
Y
E
T
I
L
V
-
E
R
-
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
----------
F
T
A
D
F
F
A
T
W
G
K
L
A
-------------
A
V
R
T
-
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
-
A
K
F
G
Q
P
E
I
K
L
G
V
L
P
G
-
M
G
G
-
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
--
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
-
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
E
A
V
N
R
A
F
E
S
S
L
S
E
G
L
L
--
Y
-
E
R
----
R
L
F
H
S
--
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
--
30
HHSearch
84.13
22%
-93
* C1 *
2PPY
3
?
A:
[7-264]
-
K
K
Q
Y
L
T
V
-
F
K
-
E
-
D
G
I
A
E
I
H
L
H
I
N
K
-
S
N
S
Y
D
L
E
F
Y
K
E
F
N
A
A
I
D
D
I
R
F
D
P
D
I
K
V
V
I
V
M
S
D
V
P
K
F
F
S
A
G
A
D
I
N
F
L
R
S
-----
A
--
D
P
--
R
F
K
T
Q
F
C
L
F
C
N
E
T
L
-
D
K
-
I
A
R
S
P
Q
-
V
Y
I
A
C
L
E
G
H
T
V
G
G
G
L
E
M
A
L
A
C
D
L
R
F
M
G
D
E
A
G
K
I
G
L
P
E
V
S
L
G
V
L
A
G
-
T
G
G
-
T
Q
R
L
A
R
L
I
G
Y
S
R
A
L
D
M
N
I
T
G
--
E
T
I
T
P
Q
E
A
L
E
I
G
L
V
N
R
V
F
P
-
Q
A
E
T
R
E
R
T
R
E
Y
A
R
K
L
A
N
S
A
T
Y
A
V
S
N
I
K
---
L
A
I
M
N
----
G
K
E
M
P
L
N
V
A
I
R
Y
E
G
E
L
Q
N
L
--
L
F
R
S
E
D
A
K
E
G
L
S
A
F
L
E
K
R
Q
P
N
W
K
G
I
10
PsiBlast_PDB
83.35
28%
-104
- C1 -
3MOY
5
?
A:
[19-260]
---------------
G
V
G
L
I
R
L
D
R
P
D
A
L
N
A
L
N
Q
T
L
E
A
E
V
L
D
A
A
R
D
F
D
A
D
L
E
I
G
A
I
V
V
T
G
S
E
-
R
A
F
A
A
G
A
D
I
A
E
M
-------------
V
T
L
T
P
H
Q
A
R
E
R
N
L
L
S
G
W
D
S
L
T
Q
V
R
K
-
P
I
V
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
L
C
D
L
V
I
A
A
D
T
-
A
R
F
G
Q
P
E
I
T
L
G
I
L
P
G
-
L
G
G
-
T
Q
R
L
T
R
A
V
G
K
A
K
A
M
D
L
C
L
T
G
--
R
S
L
T
A
E
E
A
E
R
V
G
L
V
S
R
I
V
P
-
A
A
D
L
L
D
E
A
L
A
V
A
Q
R
I
A
R
M
S
R
P
A
G
R
A
V
K
---
D
A
I
N
E
A
F
E
R
P
L
S
A
--
G
-
M
R
Y
E
-
R
D
A
F
Y
A
--
M
F
D
T
H
D
Q
T
E
G
M
T
A
F
L
E
K
R
T
P
E
F
T
D
R
28
HHSearch
83.06
24%
-101
- C1 -
3QK8
7
?
A:
[11-266]
-
D
F
P
S
L
R
F
-
E
P
G
E
-
H
G
V
L
N
L
V
L
D
S
P
G
-
L
N
S
V
G
P
Q
M
H
R
D
L
A
D
V
W
P
V
I
D
R
D
P
D
V
R
V
V
L
V
R
G
E
G
-
K
A
F
S
S
G
G
S
F
E
L
I
D
E
-----
T
--
I
G
D
Y
E
G
R
I
R
I
M
R
E
A
R
D
L
V
-
L
N
-
L
V
N
L
D
K
-
P
V
V
S
A
I
R
G
P
A
V
G
A
G
L
V
V
A
L
L
A
D
I
S
V
A
S
A
T
-
A
K
I
I
D
G
H
T
K
L
G
V
A
A
G
-
D
H
A
-
A
I
C
W
P
L
L
V
G
M
A
K
A
K
Y
Y
L
L
T
C
--
E
T
L
S
G
E
E
A
E
R
I
G
L
V
S
T
C
V
D
-
D
D
E
V
L
P
T
A
T
R
L
A
E
N
L
A
Q
G
A
Q
N
A
I
R
W
T
K
---
R
S
L
N
H
----
W
Y
R
M
F
-
G
P
T
F
E
T
S
L
G
L
E
F
L
--
G
F
T
G
P
D
V
Q
E
G
L
A
A
H
R
Q
K
R
P
A
R
F
---
19
PsiBlast_PDB
82.96
25%
-97
- C1 -
4FJW
-
ECHA8_MYCTU
D:
[1-256]
M
T
Y
E
T
I
L
V
-
E
R
-
D
-
Q
R
V
G
I
I
T
L
N
R
P
Q
A
L
N
A
L
N
S
Q
V
M
N
E
V
T
S
A
A
T
E
L
D
D
D
P
D
I
G
A
I
I
I
T
G
S
A
-
K
A
F
A
A
G
A
D
I
K
E
M
A
D
LTFAD
A
F
T
A
D
F
F
A
T
W
G
K
L
A
-------------
A
V
R
T
-
P
T
I
A
A
V
A
G
Y
A
L
G
G
G
C
E
L
A
M
M
C
D
V
L
I
A
A
D
T
-
A
K
F
G
Q
P
Q
I
K
L
G
V
L
P
G
-
M
G
G
-
S
Q
R
L
T
R
A
I
G
K
A
K
A
M
D
L
I
L
T
G
--
R
T
M
D
A
A
E
A
E
R
S
G
L
V
S
R
V
V
P
-
A
D
D
L
L
T
E
A
R
A
T
A
T
T
I
S
Q
M
S
A
S
A
A
R
M
A
K
EAV
N
R
A
F
E
S
S
L
S
E
G
L
L
--
Y
-
E
R
----
R
L
F
H
S
--
A
F
A
T
E
D
Q
S
E
G
M
A
A
F
I
E
K
R
A
P
Q
F
T
H
-
32
HHSearch
82.05
21%
-99
- C1 -
1WZ8
2
?
A:
[8-264]
-
R
Y
P
G
L
A
F
A
W
P
-
R
-
P
G
V
L
E
I
T
F
R
-
G
E
K
L
N
A
M
P
P
A
L
H
R
G
L
A
R
V
W
R
D
L
E
A
V
E
G
V
R
A
V
L
L
R
G
E
G
-
G
V
F
S
A
G
G
S
F
G
L
I
E
E
-----
M
R
A
--
S
H
E
A
L
L
R
V
F
W
E
A
R
D
L
V
-
L
G
-
P
L
N
F
P
R
-
P
V
V
A
A
V
E
K
V
A
V
G
A
G
L
A
L
A
L
A
A
D
I
A
V
V
G
K
G
-
T
R
L
L
D
G
H
L
R
L
G
V
A
A
G
-
D
H
A
-
V
L
L
W
P
L
L
V
G
M
A
K
A
K
Y
H
L
L
L
N
--
E
P
L
T
G
E
E
A
E
R
L
G
L
V
A
L
A
V
E
-
D
E
K
V
Y
E
K
A
L
E
V
A
E
R
L
A
Q
G
P
K
E
A
L
H
H
T
K
---
H
A
L
N
H
----
W
Y
R
S
F
L
P
-
H
F
E
L
S
L
A
L
E
F
L
--
G
F
S
G
K
E
L
E
E
G
L
K
A
L
K
E
K
R
P
P
E
F
P
--