@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0386: (2015-11-30 )
MAEENAQQPSLRGKSRRERVEFARSRDILDVAHELNMELFRDGKNYRWKEHDSMVITPATNQWYWFSQRQGGDVIALVETIKEIGFNQAFEYLNEGTFKEFTVVNQVKEPFSYYLEPYEQLFVEARRYLKENRGLSDDTIDFFYDKGVLAQANAKVGDMIEPVLVFKNLDKNGQVVGAALQGLVAAPDKYFGRGYLKQIMKNSQPYNGMHVDIGTPNRLVFAESSIDLMSYYEIHKDSLSDVRLVSLEGLKTGTIGRHLIQLRAEMERRPLSSSWTDEILAQGLDEAVKQGYFKDGKNSHLLTLAVDNDVKGKQLIEELKDKSIPVIDATPPKAEGQSKMDWNAYLQETKATFSTEKYQEKIDHLISDVILGDETYYLWHDDELVNLGAGDSIIQAFHHQLEDRRYVINQAELYVEESSNDGATGYLSIEGHVLDKDGISDYLSDQALTDAEKVAFLETLQTELPDIWDEIVNHYDKVFEEVVVKYGLREKHADIIQEQELDLDPLVVPEAKEKSLEMNQETNTGGELFNRNSSFLGEDSPGTAPQPVEPTAQPDFPTNVRLHFTTDDGNMSNKAFRKNMRTLNLYANTMRDSAQWYLSEIADTTMSYVYKTPHEEGVQVLSVHFGKKNWMHLTGVTPVYENWVDSLSEQFIDDIANSKGHFKNLKFALGTPDKLKVLNLLPEIIESDTFVFNDLSSVQKLNNLDLSQALNPEDSDLLLLFRDEGLHQVPASLMRIKGDLEERLSHIDSGTVLGVYRERNGQLEQVSVNEEYVKDSGQEMLSILQNKHYEEALDSGQEMVQTDGFSAEDFTKVLDAVYHVGVPDDLARVPEGVLPVWQKYLEVSEENQWDLEQMIDYADKNSLLVKDSAFYKEWKEDMIYKNDYHVRLQFAENWDNGVELPFRTEQLIDYKTFVTGLYEANQAHHQRRQESQLPYTKTEFDIYAPGGQLIKDNVHYAIGDETRPVSQLMGLGYRRLPGYQELAVIDNSILSQLENKELNQEIASEANEHSLNSQEIPKEDNYPREAFTSPKQDIKKGLAQRVEEIVAEDATKILVSSIPQVQENLSVEGNLVGTPQADNRMLYTNLEDFGQDYQLELAVYSPKRVDFLEDVQAPWTLALIRKEKKIGYLAYGSDWAKEFQIEEELEHLAAQIGDEKVPEGLYKQAEVEAFIASHQGNESLQEPIPTIVAEPFDYTSASAYEISEHAFQKIREYTQSPEDLLEYMDFMSKFPQLSPRNVALIHEQWRGANAVATYEQWKAMGEALGIKPDDVVQTKATYVNKRTGETKEVVHQGLSVKTGEKSKITLFRPLMVKMIPVLDENGQQLKNDKGNPKYKKLSEASLQEKALVKDGKLPVRQFQERDSKTGQPRFTTYKVFELSQTTLKPGSYPKAMPNRHFNFNVDKVKTKEVLEGLCDYAEKIGVSLMKDDAHVLDNAKGAFYSEEQLILINPNNTPGEKIATTIHELAHATLHNPKLEKQYKELPKGQKEFEAEMTSYLLSKHFGLDTSEKAIHYMASWTDNLKALEDKQLADSLKRVHQTVSKMLKQVEKYTNPHQLGRGKEHGLNFPKAPTKGSSR
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20...-.....30...--------.....40....------....------50........60........70........80----.....--------...90......-----.--.100.---------......110.-----..---....120.---......130.......140-----..-.--------------------------....--------------------------.150..-----.....160--.......-.170--......------..180....-...190-......-.200.-......210---...-...---.220.....-------..230----...---....240.......250.......260.......270.......280.......290.......300...--....310....-----...320--.-------..--....-..330--------.........340..-......350.......360...--....370...------..-..380........390------........400---....-----------...410..---.....420-----------------.........430....--...440...--....450---...-....460....-------...470......---------------.480.......490.......500--....---.---------....510--.......--.520....-----------...530.......540.........550......-----------.560......-.570.....--..580.......590.......600.......610.......620-.........630.......---------640.......-650........---.660.......670.....---------..680.......690........700.......710---........720.......730---.........-740--.....----------....750..--.....-760.......770...---....780.....--..790......----.800-----.......810.......820.......830.......840..-.....----850.......860-.........870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......-980.......990...------....1000......1010......1020--......1030.....------.1040......1050......1060......1070......1080......1090......1100---...----....1110......1120.----.....1130......1140.....-.1150-.....---------.1160......1170......1180........1190......1200......1210......1220----.......1230......1240......--...1250...-...1260......1270......1280...-...1290...---...1300......1310......1320......1330......1340......1350-----.......1360......-1370..---....1380......1390----......1400......1410......1420...--...1430......1440......1450......1460.-.....1470..-....1480--......1490......-------1500......1510......1520......1530......1540......1550......1560......1570...--------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEENAQQPSLRG
K
S
R
R
E
R
V
E
F
A
R-SR
D
I
L
D
V
A
H
E
--------
L
N
M
E
L
F
RDGKN------YRWK------EHD
S
M
V
I
T
PATN
Q
W
Y
W
F
SQRQGG
D
V
I
A
L
V
E
T
I
----
K
E
I
G
F
--------
N
Q
A
F
E
Y
L
NEGT-----
F
--
K
E
F
T
V
---------
V
N
Q
V
K
E
P
F
S
Y
-----
Y
L
---
E
P
Y
E
Q
L
F
V
---
E
A
R
R
Y
L
K
ENRGLSDD
T
I
D
------
F
F
-Y--------------------------DKGV--------------------------LAQANA-----KV
G
D
M
I
E
---
P
V
L
V
F
KN-LDK---NGQ
V
V
G
------
A
A
L
Q
G
L
VAA-
P
D
K
Y
F
G
-
R
G
Y
L
K
Q
-
I
M
KNS-QPYN
G
M
H
V
D---IGT-P
N
R
---
L
V
F
AESS
I
D
-------
L
M
S
Y
Y
----
E
I
H---KDSLS
D
V
R
L
V
S
L
EGLKTG
T
I
G
R
H
L
I
Q
L
R
A
E
M
ERRPLSSS
W
T
D
E
I
L
A
Q
G
L
D
E
A
V
K
QGYFKDGKN
S
H
L
L
T
L
A
--VDNDV
K
G
K
Q
L
I
-----
E
E
L
K----D-------KS--I
P
V
I-DAT----------PPKAEGQSKM-
D
W
N
-
A
Y
L
Q
E
T
KATFS
T
E
K
Y
Q
E
K
I
D
H
L
--
I
S
D
V
ILGD
E
T
------
Y
Y
-
L
WHD-D
E
L
VNLGA
G
D
-------
S
I
I
Q
A
F
H
H
Q
LE---DR
R
Y
-----------
V
I
N
Q
A
E
L
Y
---
V
EESSN-------------------DG
A
T
G
Y
L
S
I
E
G
H
V
LDK--DG
I
S
D
Y
L
SD--QAL
T
D
A
E
---
K
V
A
-
F
L
E
T
L
Q
T
E
L
P
D
-------
I
W
D
E
I
V
N
H
Y
D
K
V
---------------
F
E
E
V
V
V
KYGL
R
E
K
H
A
D
I
I
Q
E
QE----LDLD---P---------LVVPEA---KEKSLEM--NQETNTGG-----------ELFNRNSSFLGEDS--PGTAPQPVEPTAQPDFPT-----------
N
V
R
L
H
F
TTDD-GNMS
N
K
A
F
R
--
K
NM
R
T
L
N
L
Y
A
N
T
M
R
D
S
A
Q
W
Y
L
S
E
I
A
D
T
T
M
S
Y
V
YKTPHEEG
V
Q
V
---
L
S
V
HFGKK
N
W
M
H
LTGV
T
P
V
---------
Y
E
N
W
V
D
S
L
S
E
-
Q
--
F
I
D
D
I
ANS---KGHFKN
L
K
F
ALGTP
D
K
L
K
V
---------
L
N
L
L
P
E
I
IESD
T
F
V
-F
N
D
L
S
S
V
Q
K
L
NNL
D
L
S
QALN----PEDS
D
L
L
L
L
F
RDE
G
L
H
Q
V
P
-----
A
S
L
M
R
I
KG
D
-
L
----
E
E
R
L
S
----------HIDSG
T
V
L
G
--
V
Y
RER-NGQ
L
E
Q
V
SV
N
E
E
Y
V
K
D
---
S
G
Q
E
M
L
S
I
L
QN
K
--
H
Y
E
E
A
L
D
S
G
Q
E
----
M
V
Q
T-----DGF
S
A
E
D
F
T
K
V
L
D
A
V
YHVGV
P
D
D
L
A
RVP
E
G
V
L
P
V
W
Q
K
Y
L
E
VS-EENQW----
D
L
E
Q
M
I
D
YADK---N
S
L
L
VK
D
S
A
F
Y
K
E
W
K
E
D
M
I
YKN
D
Y
H
V
R
L
Q
F
AENWDNGVELPF
R
T
E
Q
L
I
D
Y
K
T
F
V
T
G
L
Y
E
A
N
Q
A
H
H
Q
R
R
Q
E
SQLPYTK
T
E
F
D
I
YAPGGQLIKDN
V
H
Y
AIGDETR
P
V
S
Q
L
M
GLGYRRLPG
Y
-
Q
E
L
A
V
I
D
N
S
I
L
S
Q
L
E
N
------
K
E
L
N
Q
E
I
A
S
E
A
NEHSL
N
S
QEIPKEDNYP--REAFTS
P
K
Q
D
I
K
K
G
L
------
A
Q
R
V
E
E
I
V
A
E
D
A
T
K
I
L
V
S
S
I
P
Q
V
Q
E
NLSVEG
N
L
VGTPQADN
R
M
L
YT
N
L
E
DFGQ
D
Y
Q
L
E
L
A
VYSP----KR
V
----
D
F
L
E
DVQAP
W
T
L
A
L
I
RKEK----K
I
G
Y
L
A
YG
S
D
W
A
K
E
F
Q
I
E
E
E
L
E
H
L
-
A
A
QIG-DEKV
P
---------
E
G
L
Y
K
Q
A
E
V
E
A
F
I
A
SHQGN
E
S
L
Q--EPI
P
T
I
VAEPFDYTSA
S
A
Y
E
I
S
E
H
A
F
Q
K
I
R
E
Y
TQ
S
P
E
D
L
L
E
-----
Y
M
D
F
M
S
KFPQLSPR
N
V
A
L
---
I
H
E
QWR--GANAV
A
T
Y
E
Q
-
W
K
A
M
G
E
ALGIKP
D
D
V
V
Q
T
K
A
T
YVNKRTG
E
T
-
K
E
V
V
H
QGLSV---KTGEK
S
K
I
T
L
F
R
P
L
M
V
K
M
IPVLDEN
G
Q
Q
LKNDKGN
P
K
Y
K
K
L
S
E
A
S
L
Q
E
K
A
LVKDGK------L
P
V
R
Q
F
Q
E
RDSKTGQP
R
-
F
T
T
Y
K
V
---
F
E
LSQTTLKPGSYPKAMP----NRHFNFN
V
D
KV
K
T
K
E
V
L
E
G
L
C
D
Y
A
E
K
I
G
V
S
L
MK--D
D
A
H
V
LDNAKGAFYSE
E
Q
L
I
L
INPNNTP
G
E
K
I
A
T
T
I
H
E
-
L
A
H
A
TLH
N
P
K
L
-
E
K
Q
Y
K
ELP--KG
Q
K
E
F
E
A
E
M
T
S
Y
L
L
S
-------
K
HFGLDT
S
E
K
A
I
H
Y
M
A
SWTD
N
L
K
A
L
E
D
K
Q
L
A
D
S
L
K
R
V
H
Q
T
V
S
K
M
L
K
Q
V
E
KYT
N
P
H
QLGRGKEHGLNFPKAPTKGSSR--------------------------------------------------------------------------------------------------------
40
Fugue
74.47
14%
1
- C1 -
3VKG
7
?
A:
[47-3244]
E
I
D
S
L
K
E
TAWSAIIPA
F
D
H
A
Q
N
L
I
K
I
Y
L
K
G
N
A
I
I
T
D
L
H
SEAIK
D
R
H
W
K
I
L
K
K
R
L
NTNWIITELT
L
G
S
I
W
D
S
DLARN
E
N
I
Y
R
E
V
I
T
A
A
Q
G
E
I
A
L
E
E
F
L
K
G
V
R
E
F
W
T
TLELD
L
V
N
Y
QRK
C
K
L
V
R
G
W
D
D
L
F
N
K
L
A
E
H
L
N
S
I
S
A
M
KMSPYYKVF
E
E
E
A
N
H
W
D
D
R
L
N
K
V
R
S
L
L
D
V
W
I
D
V
Q
R
R
W
V
Y
LEGIFINQLL
P
A
E
S
T
R
F
K
S
I
N
S
E
F
I
A
I
L
K
K
V
S
G
A
PL
I
L
E
V
L
A
IER
I
Q
Q
T
M
E
R
L
S
D
L
L
G
K
V
Q
K
A
L
G
E
Y
L
E
R
Q
R
S
A
F
A
R
F
Y
F
V
G
D
E
D
L
L
E
I
I
G
N
S
KDIIKIQKHFRKMFAGLA
N
L
T
L
D
DEKTTII
G
M
S
S
AEG
E
T
V
T
F
K
K
P
I
S
IANGPK
I
H
E
W
L
T
M
V
E
S
E
M
K
S
T
L
A
T
L
L
S
E
S
L
Q
H
F
N
Q
VDVNDHS
K
Y
S
E
W
V
D
N
Y
P
T
Q
L
V
L
L
T
S
Q
I
V
W
S
T
Q
V
D
Q
A
L
GGGTLQ
Q
S
K
I
Q
E
Q
L
Q
S
I
E
Q
T
T
Q
M
I
L
N
N
L
A
D
S
VLQDLS
A
Q
K
R
K
K
F
E
H
L
I
T
E
L
V
H
Q
R
D
V
V
R
Q
L
Q
K
CKNLTGNKDF
D
W
L
Y
H
M
R
Y
Y
Y
D
ATQENVLHK
L
V
I
H
M
AN
A
T
F
Y
YGFEYLGIGERLVQT
P
L
T
D
R
C
Y
L
T
L
T
Q
A
L
E
S
R
M
G
G
N
P
F
G
P
A
GTG
K
T
E
T
V
K
A
L
G
S
Q
L
G
R
F
V
L
V
F
C
CDEGFD
L
Q
A
M
S
R
I
F
V
G
L
C
Q
C
G
A
W
G
C
F
D
EFNRLE
E
R
I
L
S
A
V
S
Q
Q
I
Q
T
I
Q
V
A
L
K
E
NSKEVELLN
I
S
L
H
QD
M
G
I
F
V
T
M
N
P
GYAGRSNLPDNLKKL
F
R
S
M
A
M
IKPD
R
E
M
I
A
Q
V
M
L
Y
S
Q
GFKT
A
E
V
L
A
G
K
I
V
P
L
F
K
L
C
Q
E
QLSAQSHYDFG
L
R
A
L
K
S
V
L
V
S
A
G
G
I
K
R
K
CQPPD
A
E
S
K
T
K
A
D
Q
I
Y
C
Q
Y
E
I
G
V
L
L
N
S
I
N
D
TMIPKLVADD
I
P
L
I
Q
S
L
L
L
D
V
F
PG
S
Q
L
Q
P
I
QM
D
Q
L
R
K
K
I
Q
E
I
A
K
Q
R
HLVTK
Q
E
W
V
E
K
I
L
Q
L
H
Q
I
L
N
I
NH
G
V
M
M
V
G
P
S
GGG
K
T
T
S
W
E
V
Y
L
E
A
I
E
Q
V
DN
I
K
S
E
A
H
V
M
DPKAITKDQLF
G
S
L
D
LTTR
E
W
T
D
G
L
F
T
A
T
L
R
R
I
I
D
NVRGEST
K
R
H
W
I
I
F
D
G
D
V
D
PEWVENLNSLLDDNK
L
L
T
L
PNGE
R
L
A
L
P
NN
V
R
V
M
F
E
V
QDLKYATLATISR
C
G
M
V
W
F
S
EEILT
T
Q
M
I
F
Q
N
Y
L
D
T
L
S
N
E
PFD
P
Q
E
K
E
Q
Q
K
R
N
E
N
AIP
A
G
L
K
V
Q
K
E
C
A
A
I
I
SQYFEPGG
L
V
H
K
V
L
E
D
A
G
Q
RPHIMDFT
R
L
R
V
L
N
S
F
F
S
L
M
N
R
S
I
V
N
V
I
E
Y
N
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P
E
N
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N
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T
N
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L
L
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L
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L
V
E
R
E
N
F
S
K
F
I
Q
T
I
AITPVPANTIPLLD
Y
S
V
S
IDDA
N
W
S
L
WKNKVEVETHKVASPDVVIPT
V
D
T
T
R
H
V
D
V
L
H
A
W
L
S
E
HRP
L
I
L
C
G
P
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K
T
M
T
L
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L
R
A
F
P
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L
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P
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L
L
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H
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Y
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L
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T
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A
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L
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F
PS
T
S
S
L
T
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A
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D
A
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V
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F
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Y
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-
S
---
P
R
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L
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--------
W
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R
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L
L
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A
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------
M
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L
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L
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L
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-------
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----
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K
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L
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--
P
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N
----------
L
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L
Y
-----
S
N
---
W
L
T
P
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N
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---
D
L
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K
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R
L
K
V
F
Y
P
L
V
L
------
F
---------------------------------------------------------------
N
E
-----
V
L
D
H
I
L
R
---
I
D
R
V
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R
Q
-
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Q
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---
H
A
L
L
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V
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K
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-
M
N
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L
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T
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-
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L
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M
L
L
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R
---
A
G
C
-
K
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K
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F
I
F
D
E
S
N
V
L
-------
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S
S
F
L
----
E
R
M
---
N
T
L
L
A
G
G
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V
---
P
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L
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F
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R
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-------
N
L
H
-
V
V
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T
--
M
N
P
A
S
P
D
F
H
----------------------------------
N
----------
S
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L
F
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R
C
V
L
-
D
W
F
-
G
-------
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L
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I
-------------
A
P
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-------
V
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---
I
H
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-------------------
E
A
N
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L
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K
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--
K
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L
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V
---------
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-
A
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L
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----
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A
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----
L
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-
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F
L
M
N
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-
K
KITK
T
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F
M
K
----------
N
L
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A
L
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L
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-
V
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----------
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L
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L
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W
L
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-----
L
L
N
P
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A
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L
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Q
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DPIFNNSSS
K
L
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Y
LNETRSELL
F
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L
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Y
DQSTS
K
Q
N
W
Y
Q
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S
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S
SWKSD
19
HHSearch
69.69
21%
-35
- C8 -
2AU3
1
DNAG_AQUAE
A:
[3-338]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
S
D
I
D
E
L
R
R
E
I
D
I
V
D
V
I
S
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--------
Y
-
L
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CP
F
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----
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D
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--------
F
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A
A
L
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L
A
K
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Y
G----
K
K
L
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L
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-----
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L
---
L
----
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---
E
A
S
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-
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------
K
F
-
D
---------------------------
L
G
Y
A
PS
S
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A
L
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L
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DL
L
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L
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---
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G
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L
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A
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L
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-----------------------
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--
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---
F
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-----------
Y
K
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P
M
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I
L
---
L
M
K
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
68.95
15%
-1
- C3 -
3UGM
-
PTHX1_XANOP
A:
[169-1048]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
K
V
---------
R
E
L
V
A
H
I
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A
L
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--
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----
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T
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D
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
THGLT
P
A
Q
V
V
A
I
A
S
H
D
G
G
K
Q
A
L
E
T
V
Q
Q
L
L
P
V
L
C
Q
A
H
G
L
--
T
P
--------
D
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
A
T
V
----
Q
R
L
------
L
P
V
L
C
Q
A
H
G
L
----
T
P
D
----
Q
V
V
A
I
A
S
N
G
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
-
L
C
Q
-------
A
---------
H
G
L
-
T
P
D
Q
V
V
A
I
A
S
N
G
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
Q
V
Q
V
V
A
I
A
S
N
-----
I
G
G
K
Q
A
L
E
T
V
Q
R
-----
L
L
P
V
L
C
Q
A
H
G
L
T
P
A
Q
V
V
A
---
I
A
S
H
D
G
--
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
D
Q
V
V
A
I
A
S
---
N
G
G
G
K
Q
A
-
L
E
T
V
Q
R
L
L
P
G
---
L
T
Q
E
Q
V
V
A
I
A
S
N
N
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
------
L
T
P
D
Q
V
V
A
I
A
S
N
G
G
G
K
------
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
G
L
T
P
A
Q
V
---
V
A
I
A
S
N
I
----
G
G
K
Q
A
L
E
----
T
V
Q
R
L
L
P
V
L
C
Q
D
H
G
L
T
L
A
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
--
E
T
V
Q
R
L
L
P
V
L
C
Q
G
L
T
Q
D
Q
V
V
A
I
A
-
S
N
I
G
G
K
Q
A
L
E
T
V
Q
R
-
L
L
P
V
L
C
Q
D
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
-------
L
C
Q
D
H
G
L
T
L
D
Q
V
V
A
I
A
S
N
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
D
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
S
G
--------------------------------------------------------------------------------------------------------------------------------
38
Fugue
64.86
18%
-7
* C6 *
4DDU
3
RGYR_THEMA
A:
[2-1103]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVN
S
K
Y
H
HSCIN
C
G
G
L
N
T
D
E
R
N
E
R
G
L
P
C
E
V
C
L
P
E
D
S
-
P
S
D
I
Y
R
A
L
L
E
R
KTLKE
Y
R
F
Y
H
E
F
W
N
E
Y
E
D
------
F
R
S
F
------
F
K
K
K
F
G
K
D
L
T
G
Y
Q
R
L
W
A
K
R
I
V
Q
G
K
S
F
T
M
V
A
P
T
GVG
K
T
T
F
G
M
--------
M
T
A
L
W
L
A
R
K
G
K
K
S
A
L
V
F
--
P
T
V
T
L
---------
V
K
Q
T
L
E
R
L
Q
K
-----
L
A
---
D
E
K
V
K
I
F
G
---
F
Y
S
S
M
K
K
E
E
K
E
K
F
E
K
S
F
E
EDDYH
I
L
V
-
F
--------------------------
S
T
Q
F
--------------------------
V
S
K
N
R
E
-----
K
L
S
Q
K
R
F
---
D
F
V
F
V
D
D
-
V
D
A
V
L
K
A
S
R
N
I
D
------
T
L
L
M
-
M
V
G
I
-
P
E
E
I
I
R
-
K
A
F
--
S
-
T
I
K
Q
G
-
K
I
Y
E
R
P
K
N
L
-----
K
-
P
G
I
---
L
V
V
S
S
A
T
----------
A
K
P
R
----
G
I
R
---
P
L
L
F
R
D
L
L
N
F
T
V
G
R
L
V
S
--
V
A
R
N
I
T
H
V
R
I
--------
S
S
R
S
K
E
K
L
V
E
L
L
E
I
F
------
R
D
G
-----
I
L
I
F
--
A
Q
T
E
E
E
G
K
E
L
Y
-----
E
Y
L
K
----
R
-------
F
K
--
F
N
V
G
-
E
T
-----------------------
W
S
-
E
-
F
E
K
N
F
E
D
F
K
V
G
K
I
N
-----------
I
L
I
G
V
Q
A
------
Y
Y
-
G
K
L
T
-
R
---
G
V
D
L
P
E
-------
R
I
--------------
K
Y
-----------
V
I
F
W
--------------------------------
G
T
P
S
M
R
F
S
L
E
L
D
K
A
P
R
--
F
V
L
A
R
V
L
K
E
--
M
G
L
I
K
A
Q
E
N
P
D
V
E
-
E
L
R
K
I
A
K
E
H
L
T
--------
Q
K
E
F
V
E
K
V
K
E
M
---------------
F
R
G
V
V
V
K
------------
D
E
D
----
L
------
E
---------
L
I
I
P
D
----------------
V
Y
T
Y
I
-----------
Q
A
S
G
R
S
S
R
I
L
N
G
V
L
--
V
K
G
V
S
V
I
F
E
E
D
E
E
I
F
E
S
L
-----------
K
T
R
L
L
L
I
A
E
E
------
E
I
I
E
--
E
A
E
A
N
W
K
E
L
V
H
E
V
E
E
S
R
R
R
S
E
R
E
L
T
D
T
S
R
S
L
L
I
I
V
E
S
P
T
K
A
E
T
---
L
S
R
F
L
G
R
---------------------------------------------------------------------------------------------
A
S
S
R
K
E
R
N
I
I
V
H
E
A
V
T
----
G
E
G
---
V
I
L
F
T
A
T
R
G
H
V
Y
D
-----
L
------------------------------
V
T
K
G
G
I
H
G
--
V
-
E
E
E
-
N
G
K
F
V
P
V
Y
N
S
L
K
R
C
R
D
---
C
G
Y
Q
F
T
--------------
E
D
R
D
E
----
C
P
V
C
-----
S
S
K
N
I
D
D
K
T
E
T
L
R
A
L
R
E
I
S
L
E
A
D
------
E
I
L
V
A
T
D
P
D
V
E
-
G
-
E
K
I
S
W
----
D
V
T
Q
Y
L
L
P
S
T
R
---
S
L
R
R
I
E
--------------------------------------------------
M
H
E
I
T
R
Y
G
F
K
K
A
R
E
S
------------------------------
V
R
F
V
----------------
D
F
N
L
V
K
A
Q
I
V
R
R
V
Q
D
------
R
W
I
G
F
E
L
S
G
K
L
Q
K
R
F
---------------------
G
R
S
N
L
S
A
G
-----------------
R
V
Q
S
T
V
L
G
W
I
V
E
R
E
E
E
Y
K
K
S
---------------------------------------------------
E
K
D
F
T
L
L
V
L
---------------------
E
N
G
V
N
L
E
V
E
----
G
K
I
A
-
D
D
V
V
T
---------
V
V
E
L
Q
E
A
E
E
E
K
--------------
N
P
L
P
-----
P
Y
T
-
T
S
S
A
L
S
E
I
S
Q
K
L
R
L
G
V
Q
E
V
M
D
I
L
Q
D
L
F
E
K
GFIT
Y
H
R
T
D
S
T
R
I
S
L
E
G
Q
N
V
A
R
---
T
Y
L
R
K
I
--
G
K
E
D
I
F
M
G
R
S
-
W
S
T
E
G
A
H
E
A
I
R
P
-------
V
K
P
I
D
A
R
--
E
L
-
E
E
M
I
E
E
G
L
I
A
DLT
K
K
H
L
R
V
Y
E
L
I
F
N
R
F
L
A
S
Q
S
A
A
V
K
V
K
K
Q
I
V
T
V
D
V
D
G
K
-----
R
M
G
I
E
Q
I
V
E
I
L
R
D
G
------------
W
N
L
F
V
P
L
T
V
S
P
R
-
F
E
-
H
R
T
---
Y
K
I
K
E
K
K
F
Y
K
K
H
T
V
P
L
F
T
--------------------
Q
A
S
I
V
E
E
M
K
K
R
G
I
G
R
P
S
--
T
Y
A
K
I
V
E
V
L
F
R
R
G
Y
-----
V
Y
E
D
K
Y
K
R
--------
V
R
P
-
T
R
F
G
V
M
V
Y
S
Y
L
-
K
E
R
Y
E
K
Y
--------------------------------
V
T
E
E
T
T
R
R
L
E
E
I
M
D
K
V
E
R
G
E
E
D
-
Y
Q
A
T
L
R
L
L
Y
E
E
I
K
S
L
M
E
E
--------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
61.07
20%
34
- C6 -
4OPU
3
?
A:
[2-453]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
E
-
L
K
Y
---
D
V
L
I
I
G
------
G
G
F
A
G
S
S
A
A
--
Y
Q
L
S
R
-
R
G
-
L
K
I
-
L
L
V
D
S
-
K
P
W
N
R
-------
I
G
D
K
P
C
G
---
D
A
V
S
K
A
H
F
D
-------
K
L
G
M
P
YPKG
E
E
L
---
E
N
K
I
N
G
I
K
L
Y
S
P
D
M
Q
T
V
W
T
V
N
H
E
G
F
E
L
N
------------
A
P
L
Y
N
Q
R
V
L
K
E
A
Q
D
R
G
V
E
I
W
D
L
T
T
A
M
K
P
I
F
--
E
D
G
Y
V
K
G
A
V
L
F
NRRTN
E
E
L
T
----
V
-------
Y
S
--
K
V
V
V
-
E
A
T
GYSRSFRSKL
P
P
E
L
P
I
T
E
D
L
-
D
D
K
-
D
A
D
V
A
Y
R
E
V
L
L
T
K
E
D
I
E
--
D
H
D
--
Y
L
R
I
F
I
D
Q
E
T
SPG
G
Y
W
W
Y
-
F
P
K
G
-
K
N
K
V
N
V
G
L
G
I
Q
G
GMGYP
S
I
H
E
Y
Y
K
K
Y
L
D
---
K
Y
A
P
-----------
D
V
D
K
S
K
L
L
---
V
K
G
G
A
L
V
P
TRRPLYTMAWNG
I
I
V
I
G
D
S
G
F
T
V
N
P
V
H
G
G
G
K
G
S
--
A
M
I
S
G
Y
C
A
A
--
K
A
I
L
S
A
F
---
E
------
T
G
D
F
S
A
S
G
-------
L
W
D
M
N
I
C
Y
V
N
E
-----------------------
Y
G
A
K
Q
A
S
L
D
I
F
R
R
F
L
----
Q
K
L
S
-----------------------
N
D
D
I
N
Y
--
G
M
K
K
K
I
I
K
-----------
E
E
D
L
L
E
A
S
E
K
G
D
L
H
--
L
S
V
A
D
K
A
M
R
V
I
S
G
L
G
R
P
S
-----------
L
L
F
K
L
K
A
V
A
E
-
S
M
K
K
I
K
E
L
Y
--
L
N
Y
P
R
S
P
S
S
L
G
S
W
R
R
E
V
D
N
V
L
T
E
F
N
K
S
L
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
56.26
22%
8
- C8 -
1DD9
1
DNAG_ECOLI
A:
[42-260]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
---
S
A
R
Q
Y
L
E
-
K
R
G
L
S
H
E
V
I
A
------
R
F
-
A
I
G
F
APPGWD
N
V
L
K
R
FGGN
P
E
N
R
Q
S
L
I
D
A
G
M
--------------------------
L
V
T
N
-------
R
S
Y
D
R
F
R
---
E
R
V
M
F
P
I
-
R
D
K
---
R
G
R
V
I
G
------
F
G
G
R
V
L
G
N
D
-
T
P
K
Y
L
N
-
S
P
E
-
T
D
-
I
F
H
K
G
-
R
Q
L
Y
G
L
Y
E
A
Q
Q
D
N
A
E
-
P
N
R
---
L
L
V
V
E
G
Y
M
D
-------
V
V
A
L
A
----
Q
Y
------
G
I
N
Y
A
--
V
A
S
L
G
-
S
-----------------------
T
T
A
D
H
I
Q
-
L
L
---------
F
--
R
A
T
N
N
V
I
C
C
--
Y
D
G
D
R
A
G
R
D
A
A
-----
W
R
A
L
----
E
T
A
LPYMT
D
G
--
R
Q
L
R
-
F
M
F
----------
L
P
-----
D
G
E
-
D
P
D
-
T
L
V
R
K
E
G
K
E
A
F
E
A
R
M
E
Q
A
M
P
L
S
--
A
F
L
F
N
S
L
M
P
Q
------
V
D
-
L
S
T
P
-
D
G
R
A
R
L
S
T
L
A
-------
L
P
L
I
S
Q
V
P
G
E
T
---
L
R
I
Y
-----------
L
R
Q
E
L
G
N
K
---
L
G
I
L
D
D
-------------------
S
Q
L
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
54.06
14%
-2
- C7 -
1C3J
1
GSTB_BPT4
A:
[1-351]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
I
A
------
I
I
N
M
--------------------------
G
N
N
V
--------------------------
I
N
F
K
T
V
-----
P
S
S
E
T
I
Y
---
L
F
K
V
I
S
E
-
M
G
L
---
N
V
D
I
I
S
------
L
K
N
G
V
Y
T
K
S
-
F
D
E
V
D
V
-
N
D
Y
D
R
L
-
I
V
V
N
S
N
L
A
I
L
S
A
Q
K
F
---
M
A
K
-
Y
K
S
---
K
I
Y
Y
L
F
T
-
D
-------
I
R
L
P
F
----
S
Q
S
---
A
Y
L
Y
T
E
E
E
L
L
I
K
S
P
I
K
V
I
S
Q
G
I
N
L
D
I
A
K
A
A
H
K
K
V
D
N
V
I
E
F
E
Y
F
P
I
E
Q
Y
K
I
H
M
N
D
F
Q
L
S
K
P
T
K
K
T
L
D
V
I
Y
G
G
S
F
R
S
G
Q
R
E
S
K
M
V
-----
E
F
L
F
----
D
TG-----
L
N
--
I
E
F
F
-
G
N
A
----------
R
E
K
Q
F
K
N
P
K
Y
-
P
W
T
-
K
A
P
V
F
T
G
K
I
-
P
M
N
M
V
S
E
K
N
S
Q
A
--
I
A
A
L
I
I
G
D
K
N
------
Y
N
D
N
F
I
T
-
L
R
V
W
E
T
M
A
S
D
-------
A
-
V
M
L
I
D
E
E
F
D
---
T
K
H
R
-----------
I
I
N
D
A
R
F
Y
---
V
N
-------------------------------------
N
R
--
A
E
L
I
D
R
V
N
E
--
L
K
H
S
D
V
L
---
R
K
E
-
M
L
S
I
Q
H
D
I
L
N
K
-------
T
R
A
K
-
K
A
E
W
Q
D
A
---------------
F
K
K
A
I
D
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
53.70
17%
14
- C8 -
1NUI
3
PRIM_BPT7
A:
[20-250]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
------
S
S
D
G
N
S
L
F
S
-
D
G
H
T
F
C
Y
V
C
E
K
W
T
A
----
T
-----------------------
K
E
R
A
S
K
R
K
-----
P
--
S
--
G
G
---------
K
P
G
T
Y
N
V
W
-------
N
F
---
G
----
E
S
N
---
G
R
Y
S
A
L
T
-
A
R
G
I
S
K
E
T
C
Q
------
K
A
------------------------------
G
Y
--------------------------
W
I
A
K
V
--------
D
--
G
V
---
M
Y
Q
V
A
D
Y
-
R
D
Q
---
N
G
N
I
V
S
------
Q
K
V
R
D
K
D
-----
K
N
------
F
K
T
T
G
S
H
K
S
-
D
A
L
F
G
K
H
L
W
----
N
G
-
G
K
K
---
I
V
V
T
E
G
E
I
D
-------
M
L
T
V
M
----
E
L
Q
-----
D
C
K
Y
-
P
V
V
S
L
G
H
G
A
S
--
A
A
--------------------
K
K
T
C
A
A
N
Y
---------
E
Y
F
D
Q
F
E
Q
I
I
L
M
--
F
D
M
D
E
A
G
R
K
A
V
-----
E
E
A
A
----
Q
-------
V
L
PA
G
K
V
R
-
V
A
V
----------
L
P
------
C
K
-
D
A
N
-
E
C
H
L
N
G
H
D
R
E
I
M
E
Q
V
W
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
51.41
21%
19
- C8 -
1Q57
-
PRIM_BPT7
A:
[73-249]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
N
---
G
R
Y
S
A
L
T
-
A
R
G
I
S
K
E
T
C
Q
------
K
A
------------------------------
G
Y
--------------------------
W
I
A
K
V
----------
D
G
V
---
M
Y
Q
V
A
D
Y
-
R
D
Q
---
N
G
N
I
V
S
------
Q
K
V
R
D
K
D
-----
K
N
------
F
K
T
T
G
S
H
K
S
-
D
A
L
F
G
K
H
L
W
----
N
G
-
G
K
K
---
I
V
V
T
E
G
E
I
D
-------
M
L
T
V
M
----
E
L
Q
---
D
--
C
K
-
Y
P
V
V
S
L
G
H
G
A
S
A
A
----------------------
K
K
T
C
A
A
N
Y
---------
E
Y
F
D
Q
F
E
Q
I
I
L
M
--
F
D
M
D
E
A
G
R
K
A
V
-----
E
E
A
A
----
Q
-------
V
L
PA
G
K
V
R
-
V
A
V
----------
L
P
------
C
K
-
D
A
N
-
E
C
H
L
N
G
H
D
R
E
I
M
E
Q
V
W
N
A
G
P
W
I
--
P
D
G
V
V
S
A
L
S
L
------
R
E
-
R
I
R
E
-
H
L
S
S
E
E
S
V
G
L
-------
L
F
S
G
C
T
G
I
N
D
K
---
T
L
G
A
-----------
R
G
G
E
V
I
M
V
---
T
S
G
S
G
M
-------------------
V
M
S
T
F
V
R
Q
Q
A
L
Q
W
G
T
A
--
M
G
K
K
V
G
L
A
M
--
L
E
E
S
V
E
E
---
T
A
E
-
D
L
I
G
L
H
N
R
V
R
L
-------
R
Q
S
D
S
L
K
R
E
I
I
E
---------------
N
G
K
F
D
Q
W
F
D
E
L
F
G
N
D
T
F
H
L
Y
D
S
----
F
E
T
D
---
R
---------
L
L
A
K
L
A
---
Y
M
R
S
G
L
G
--
C
D
V
I
I
L
D
H
-----------
I
S
I
V
V
S
A
S
G
E
S
D
E
R
--
K
M
I
D
N
L
M
T
K
L
K
G
F
A
K
S
T
G
-----------
V
V
L
V
V
I
C
H
L
K
-
N
P
D
K
G
K
A
H
E
--
E
G
R
P
V
S
I
T
D
L
R
G
S
G
A
L
R
Q
L
S
D
T
I
I
A
L
E
R
N
Q
Q
G
D
M
P
N
L
V
L
V
R
I
L
---
K
C
R
F
T
G
D
T
G
I
A
G
Y
M
E
Y
N
K
E
---------
T
G
W
L
E
P
S
S
Y
S
-
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
48.91
27%
15
- C8 -
2AU3
1
DNAG_AQUAE
A:
[9-173]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
R
R
-
E
I
D
I
V
D
V
I
S
E
Y
-------
L
N
L
E
--
K
V
G
S
N
------
Y
R
T
N
CPFHPD
D
T
P
S
F
Y
V
S
P
S
K
Q
I
F
K
C
F
G
C
G
V
G
G
D
A
I
K
F
V
S
L
Y
----
E
D
I
S
Y
--------
F
E
A
A
L
E
L
A
K
R
Y
-----
G
--
K
K
L
D
L
---------
E
K
I
S
K
D
E
K
V
Y
V
A
L
D
R
V
C
---
D
F
Y
R
E
S
L
L
K
N
R
E
A
S
E
Y
V
K
-
S
R
G
I
-
D
P
K
V
A
------
R
K
-
F
--------------------------
D
L
G
Y
--------------------------
A
P
S
S
E
A
L
V
K
V
L
K
E
N
D
L
L
E
---
A
Y
L
E
T
K
N
-
L
L
S
---
P
T
K
G
V
Y
------
R
D
L
F
L
R
R
V
V
-
I
P
I
K
D
P
-
R
G
R
V
I
G
-
F
G
G
R
R
-
I
V
E
D
K
S
P
K
Y
---
I
N
S
-
P
D
S
---
R
V
F
K
K
G
E
N
L
-------
F
G
L
Y
E
----
A
K
E
---
Y
I
K
E
E
G
F
A
I
L
V
E
G
Y
F
D
L
L
R
L
F
S
E
G
I
R
N
V
V
A
P
L
G
T
A
L
T
Q
N
Q
A
N
L
L
S
K
F
T
K
K
V
Y
I
L
Y
D
G
D
D
A
G
R
K
A
M
K
S
A
I
P
--
L
L
L
S
A
G
V
E
V
Y
P
-----
V
Y
L
P
----
E
-------
G
Y
--
D
P
D
E
-
F
I
K
----------
E
F
G
K
E
E
L
R
R
L
-
I
N
S
-
S
G
E
L
F
E
T
L
I
K
T
A
R
E
N
L
E
E
K
T
R
E
--
F
R
Y
Y
L
G
F
I
S
D
------
G
V
-
R
R
F
A
-
L
A
S
E
F
H
T
K
Y
K
-------
V
P
M
E
I
L
L
M
K
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
48.33
17%
-15
- C4 -
4LXR
11
TOLL_DROME
A:
[1-773]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
F
G
R
---
D
A
C
S
E
M
S
I
D
GL
C
Q
C
A
P
I
M
S
E
Y
----
E
I
I
C
PA
N
A
E
N
P
T
F
R
L
T
I
Q
P
K
--------
D
Y
V
Q
I
M
C
N
L
T
D
T
T
D
Y
Q
Q
L
P
K
K
L
R
I
G
E
V
D
R
V
Q
M
R
R
C
M
L
P
G
H
T
P
I
A
S
I
L
D
--
Y
L
G
I
V
S
P
T
T
L
I
-----
F
E
S
D
----
N
-------
L
G
--
M
N
I
T
-
R
Q
H
----------
L
D
R
L
H
G
L
K
R
F
-
R
F
T
T
R
R
L
T
H
I
P
A
N
L
L
T
D
--
M
R
N
L
S
H
L
--
E
L
R
A
N
I
E
E
M
P
------
S
H
-
L
F
D
D
L
E
N
L
E
S
I
E
F
G
S
-------
N
K
L
R
Q
M
P
R
G
I
F
---
G
K
M
P
-----------
K
L
K
Q
L
N
L
W
SNQ
L
H
N
L
T
K
-------------------
H
D
F
E
G
A
T
S
V
L
G
I
D
I
H
D
--
N
G
I
E
Q
L
P
H
D
VF
A
H
L
T
N
V
T
---
D
I
N
-
L
S
A
N
L
F
R
S
L
P
Q
GLFDHNK
H
L
N
E
V
R
L
M
N
N
R
V
PLATLPSRLFANQPE
L
Q
I
L
R
L
R
A
E
L
Q
S
L
P
G
D
L
F
E
H
S
T
QIT
N
I
S
L
G
---
D
NLLKTLPAT
L
L
E
H
Q
V
---
N
L
L
S
L
D
L
SN
N
R
L
T
H
L
P
D
-----------
S
L
F
A
H
T
T
N
L
T
D
L
R
L
--
E
D
N
L
L
T
G
I
S
G
D
I
F
S
N
L
G
N
-----------
L
V
T
L
V
M
S
R
N
R
L
R
T
I
D
S
R
A
F
V
ST
N
G
L
R
H
L
H
L
D
H
N
D
I
-
D
L
Q
Q
P
L
L
D
I
M
L
Q
T
Q
I
N
S
P
F
G
Y
M
H
--
G
L
L
T
---
L
N
--------
L
R
N
N
S
I
I
F
V
---------
Y
N
D
W
K
N
T
M
L
Q
L
R
--
E
L
D
L
S
Y
N
N
---
I
S
S
L
G
Y
E
D
L
A
F
L
S
Q
N
R
L
H
V
N
MTHNKIR
R
I
A
L
P
E
D
V
N
N
N
L
V
H
V
D
L
N
D
N
P
L
V
C
D
C
T
I
L
W
F
I
Q
L
V
R
GVHK
P
Q
Y
S
R
Q
F
K
L
R
T
D
R
L
V
C
S
Q
P
NVLEG
T
P
V
R
Q
I
E
P
Q
T
L
----
I
C
P
L
D
F
SKCPRG
C
N
C
H
V
R
T
Y
D
K
A
L
--
V
I
N
C
H
-
S
G
N
L
T
H
V
P
R
L
P
N
L
H
K
N
---
M
Q
L
M
E
L
H
L
E
N
N
T
LL
R
L
P
S
A
N
T
P
G
Y
E
----
S
V
T
S
LHLAG
N
N
L
T
S
I
D
V
D
Q
L
P
T
N
L
T
H
L
D
I
S
W
N
H
L
Q
M
L
N
A
T
V
L
G
F
L
N
W
R
S
V
K
L
S
G
N
P
W
MCDC
T
A
K
P
L
L
L
F
T
Q
D
---
N
F
E
R
I
G
D
-------
R
N
E
M
M
C
V
N
A
P
T
R
M
V
E
L
S
T
N
D
I
C
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
47.86
27%
80
- C8 -
1D0Q
1
DNAG_GEOSE
A:
[4-92]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
P
E
E
T
I
E
A
I
R
R
G
V
D
I
V
D
V
I
G
E
--------
Y
-
V
Q
L
K
R
Q
G
R
N
Y
F
G
L
C
P
F
H
G
E
------
K
T
P
S
F
S
V
S
P
E
K
Q
I
F
H
C
F
G
C
G
A
G
G
N
A
F
T
F
L
M
D
I
----
E
G
I
P
F
--------
V
E
A
A
K
R
L
A
A
K
A
-----
G
--
V
D
L
S
V
---------
Y
E
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
47.69
18%
-4
* C7 *
4M1K
2
?
A:
[6-688]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
D
L
K
R
L
----
R
N
I
G
I
A
A
H
IDAG
K
T
T
T
T
E
R
I
L
Y
Y
T
-----
G
--
R
I
A
A
V
---------
T
T
C
F
W
K
D
H
R
I
-----
N
I
I
DT
P
G
H
V
D
F
T
I
---
E
V
E
R
S
M
R
----
V
L
D
G
A
I
V
------
V
F
-
D
S-------------------------
S
Q
G
V
--------------------------
E
P
Q
S
E
T
-----
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
---
T
G
----------
A
D
L
W
L
V
I
R
T
-
M
Q
E
R
L
G
A
R
P
V
V
M
Q
-
L
P
I
G
R
-
E
D
T
F
S
G
I
I
D
---
V
L
R
-
M
K
A
---
Y
T
Y
G
N
D
L
G
T
-------
D
I
R
E
I
----
P
I
P
---
E
E
Y
L
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
E
N
I
M
L
K
Y
L
E
G
E
E
P
-----
T
E
E
E
L
V
A
A
I
R
K
G
T
I
-----
D
L
K
I
T
P
V
F
L
G
S
--
A
L
K
N
K
G
V
Q
L
L
L
-----
D
A
V
V
----
D
YLPSP--
L
D
--
I
P
P
I
-
K
G
T
----------
T
P
E
G
E
V
V
E
I
H
P
D
P
N
-
G
P
L
A
A
L
A
F
K
I
M
A
D
P
Y
V
G
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
------
V
Y
-
N
-------
T
T
K
G
R
K
E
-------
R
V
A
R
L
L
R
M
H
A
N
---
H
R
E
E
V
EELKAG
D
L
G
A
V
V
G
L
K
E
T
I
---
T
G
D
T
L
V
-------------------
G
E
D
A
P
R
V
I
L
E
S
I
E
V
P
E
--
P
V
I
D
V
A
I
E
P
--
K
T
K
A
D
Q
E
---
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
-------
F
R
V
S
T
H
P
E
T
G
Q
T
---------------
I
I
S
G
M
G
E
L
H
L
E
I
I
V
D
R
L
K
R
E
F
K
----
V
D
A
N
VGK
P
---------
Q
V
A
Y
R
E
T
I
T
K
P
V
D
V
E
G
--
K
F
I
R
L
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
E
P
L
P
R
G
S
G
F
E
F
V
N
A
IV
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
QSGPLIGFP
V
V
D
I
K
V
T
L
Y
D
-
G
S
Y
H
E
V
D
S
S
---
E
M
A
F
K
I
A
G
S
M
A
I
K
E
A
V
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
P
E
E
Y
M
G
D
V
I
G
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
G
N
A
Q
V
---------
I
R
A
F
V
P
-
L
A
E
-
M
FG
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
K
Q
V
Q
---------
E
K
L
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.29
25%
34
- C5 -
2WUA
-
?
A:
[47-282]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
D
V
V
I
V
A
A
Y
R
S
P
L
C
K
A
K
R
G
GLKD
T
Y
P
D
D
I
L
A
P
V
L
K
A
L
I
E
K
T
N
INPA
E
V
G
D
I
V
V
G
S
V
L
G
A
G
S
Q
R
A
S
E
C
R
M
A
-
A
F
Y
A
G
F
P
E
T
V
P
V
R
T
V
N
RQCS
S
G
L
Q
A
V
A
D
V
A
A
A
I
K
A
G
F
Y
D
I
G
I
G
--
A
G
L
E
S
M
T
A
N
P
M
------
A
W
E
G
S
V
N
P
--
K
V
K
T
M
A
Q
A
Q
D
C
L
L
P
-----
M
--------
G
I
T
S
E
N
V
A
Q
K
F
S
I
T
R
Q
E
Q
--
D
Q
A
A
V
G
S
H
R
K
--
T
A
A
A
T
A
A
G
R
F
K
D
E
I
I
P
I
K
T
K
I
V
D
P
K
T
G
D
E
-
K
P
V
T
---
I
S
V
---
D
D
G
I
R
P
G
T
S
L
A
D
--
L
A
K
L
K
P
V
F
R
K
D
G
S
T
T
A
G
T
S
S
Q
V
S
D
G
A
G
A
V
L
L
M
K
R
S
I
A
L
Q
K
G
L
------
P
I
L
G
V
F
R
T
F
A
A
V
G
V
P
P
S
-
I
M
G
I
G
P
---
A
V
A
I
P
A
A
V
K
A
A
G
L
Q
I
D
D
I
----
D
L
F
E
I
N
E
A
F
A
S
Q
F
V
Y
C
Q
K
K
L
E
I
D
P
Q
K
I
N
V
N
G
G
A
--
M
A
I
G
H
P
L
G
A
T
G
A
R
C
V
A
T
L
L
H
E
M
K
R
R
G
R
D
C
R
F
G
V
V
S
M
C
I
-
G
T
G
M
G
A
A
A
V
F
E
-
R
G
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
42.53
27%
265
- C5 -
3J0J
-
VATB_THET8
D:
[275-373]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
I
P
G
R
R
G
Y
P
G
Y
M
Y
T
D
L
A
T
I
Y
E
R
A
G
V
V
E
G
K
KGSVTQ
I
P
I
L
S
M
P
D
D
D
R
T
H
P
I
P
D
-
L
T
G
Y
I
T
EGQ
I
Q
L
S
R
E
L
H
R
K
G
I
Y
P
P
I
D
P
LPSL
S
R
L
M
N
N
G
V
G
K
G
K
T
R
E
D
H
K
Q
V
S
D
Q
L
Y
S
A
Y
A
N
G
V
D
--
I
R
K
L
V
A
I
I
G
E
D
A
L
T
E
N
D
R
R
Y
L
Q
F
A
D
A
F
E
R
F
F
I
N
Q
G
Q
Q
N
-
R
S
I
E
E
S
L
Q
I
A
W
-
A
L
L
S
M
L
P
Q
--
G
E
L
K
R
I
S
K
D
H
I
G
K
Y
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
42.16
23%
112
- C5 -
3PRH
-
SYW_BACSU
A:
[198-327]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
P
N
Q
K
A
Y
I
T
L
L
D
--
E
P
K
Q
L
E
K
K
I
K
S
A
V
T
D
S
E
G
I
V
K
F
D
K
E
N
K
P
G
V
S
N
L
L
T
I
Y
S
I
L
G
N
T
T
I
E
--
E
L
-
E
A
K
Y
E
--
G
--
K
G
Y
G
E
F
K
G
D
L
A
E
V
V
V
N
A
L
K
P
I
Q
D
R
Y
Y
E
L
I
E
S
E
E
L
---------------
D
R
I
L
D
E
G
A
E
R
A
N
R
T
A
N
K
M
L
K
K
M
E
---
N
A
M
G
L
G
R
--------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
42.07
27%
260
- C5 -
3W3A
-
VATB_THET8
D:
[269-367]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
I
P
G
R
R
G
Y
P
G
Y
M
Y
T
D
L
A
T
I
Y
E
R
A
G
V
V
E
G
K
KGSVTQ
I
P
I
L
S
M
P
D
D
D
R
T
H
P
I
P
D
-
L
T
G
Y
I
T
EGQ
I
Q
L
S
R
E
L
H
R
K
G
I
Y
P
P
I
D
P
LPSL
S
R
L
M
N
N
G
V
G
K
G
K
T
R
E
D
H
K
Q
V
S
D
Q
L
Y
S
A
Y
A
N
G
V
D
--
I
R
K
L
V
A
I
I
G
E
D
A
L
T
E
N
D
R
R
Y
L
Q
F
A
D
A
F
E
R
F
F
I
N
Q
G
Q
Q
N
-
R
S
I
E
E
S
L
Q
I
A
W
-
A
L
L
S
M
L
P
Q
--
G
E
L
K
R
I
S
K
D
H
I
G
K
Y
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
41.86
27%
264
- C5 -
3A5D
-
VATB_THET8
D:
[275-373]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
I
P
G
R
R
G
Y
P
G
Y
M
Y
T
D
L
A
T
I
Y
E
R
A
G
V
V
E
G
K
KGSVTQ
I
P
I
L
S
M
P
D
D
D
R
T
H
P
I
P
D
-
L
T
G
Y
I
T
EGQ
I
Q
L
S
R
E
L
H
R
K
G
I
Y
P
P
I
D
P
LPSL
S
R
L
M
N
N
G
V
G
K
G
K
T
R
E
D
H
K
Q
V
S
D
Q
L
Y
S
A
Y
A
N
G
V
D
--
I
R
K
L
V
A
I
I
G
E
D
A
L
T
E
N
D
R
R
Y
L
Q
F
A
D
A
F
E
R
F
F
I
N
Q
G
Q
Q
N
-
R
S
I
E
E
S
L
Q
I
A
W
-
A
L
L
S
M
L
P
Q
--
G
E
L
K
R
I
S
K
D
H
I
G
K
Y
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
41.76
27%
265
- C5 -
3A5C
-
VATB_THET8
D:
[275-373]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
I
P
G
R
R
G
Y
P
G
Y
M
Y
T
D
L
A
T
I
Y
E
R
A
G
V
V
E
G
K
KGSVTQ
I
P
I
L
S
M
P
D
D
D
R
T
H
P
I
P
D
-
L
T
G
Y
I
T
EGQ
I
Q
L
S
R
E
L
H
R
K
G
I
Y
P
P
I
D
P
LPSL
S
R
L
M
N
N
G
V
G
K
G
K
T
R
E
D
H
K
Q
V
S
D
Q
L
Y
S
A
Y
A
N
G
V
D
--
I
R
K
L
V
A
I
I
G
E
D
A
L
T
E
N
D
R
R
Y
L
Q
F
A
D
A
F
E
R
F
F
I
N
Q
G
Q
Q
N
-
R
S
I
E
E
S
L
Q
I
A
W
-
A
L
L
S
M
L
P
Q
--
G
E
L
K
R
I
S
K
D
H
I
G
K
Y
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
40.60
16%
104
* C8 *
2FCJ
-
?
A:
[3-96]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
-
V
E
K
---
V
I
I
V
E
G
R
S
D
-------
K
Q
K
V
A
----
A
V
------
L
N
E
P
V
V
I
V
C
T
N
G
T
----
I
S
D
--------------------
A
R
L
E
-
E
L
A
---------
D
E
L
E
G
Y
D
V
Y
L
L
--
A
D
A
D
E
A
G
E
K
L
R
-----
R
Q
F
R
----
R
-------
M
F
--
P
E
A
E
H
L
Y
I
----------
D
R
-----
A
Y
R
-
E
V
A
-
A
A
P
I
W
H
L
A
Q
V
L
L
R
A
R
F
D
V
R
I
E
S
--
L
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------