@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0391: (2015-11-30 )
MKQIKIITGLTVATLSAVVGNVYAEDITPTAPVNEPQVSSETAKTPQVTESQVNSAKVTADQAISDVNNQQIVVDEAQKQKDQSQQNLVKATSTVTEAEKVAAEATPEVVKEAIKAVTEAKEAVTDAEANVVDAQKTEQKANQEVQSQAKTVDENVKVVADKESEVKQAEGVVTTAQEAIDSKTANTNASEAEKAVTEKQTKLETAETNLTEAQKQDAKIAEEKRLAEQEVVNKQLAVTDTQTLLKKLVTEINNEKVSTSLENQAYFNQRDGSWAGYYGNYTFAATGCVPSSLAMVFTELARRQITPTEIANYLWNNSNEFNKNYGGTSGKGLVQATKHFGFVPTHLASQSAIVEALQAGHHVLAAVQQDKFSPWGINYSHEIVLRGYSNGNTYVYDPYNRANIGWYPVANLWNEQSRDAIDTSSVGVPFFKITTQKMAQLEAQKAQVQSSLNTAKNQLAKTQDVLRTLEATPLKTPEAQAKLNQAKEALALAQADYTKAQEAVKLASQDLAVKEETLKNAQADLLTKQTALKDAQTVLVASQVKLADLKATLATVENNVKKAQATLTDAKAIVGQKQAKLLALQNAPKILADAQAKLVTAKNDLANKMAILDEAVAKLKSLQAVQAEAQKQYHVVFEAYKAVRDAKEQAKLAESYNHIIARGGEAIPVVDETDKITGYVDGSQKAVANEVTLALTSNGAPLESPVNKENQNVTKSSQALPHTGEAGLSILSVLGVGLISTLGLTSLKKRRPH
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90.-.......100.......110.......120.......130.......140-....-...150.......--160......---------.170.......180.--...-.--..-190.------......200.......210-.......-.220......---.230.-----------......240--------.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450--.......460.......470.......480.......490.......500.......510.......520.......530.......540----........550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
Q
I
K
I
I
T
G
L
T
V
A
T
L
S
A
V
V
G
N
V
Y
AEDITPTAPVNEPQVSSETAKTPQV
T
E
SQVNS
A
K
V
T
A
D
Q
A
ISDVNN
Q
Q
I
V
V
D
E
A
Q
KQK
D
Q
S
Q
Q
N
L
V
K
A
T
-
S
T
V
T
E
A
E
K
V
A
A
EA
T
P
E
V
V
K
E
A
I
K
A
V
T
E
A
K
E
AVTDAEANVV
D
A
Q
K
T
E
Q
K
A
N
-
Q
E
V
Q
-
S
Q
A
K
TVDEN
V
K
V
V
--ADKE
S
E
V
K
Q
---------AEGV
V
T
T
A
Q
E
A
IDSK--TAN-T--
N
A
-
S
E
A
E
------
K
A
V
T
E
K
Q
TKLETAETN
L
T
--
E
A
Q
K
Q
D
A
-
K
I
A
E
E
K
R
L
A
E
---
Q
E
V
VN-----------KQLAVT
D
T
Q
--------
T
L
L
K
K
L
V
T
E
IN
N
E
K
VSTSLENQ
A
Y
FNQRDG
S
W
A
G
Y
YG
N
Y
T
F
A
ATGCV
P
S
S
L
A
M
V
F
T
E
L
A
RRQI
T
P
T
E
I
A
N
Y
L
WNNSNEFNKNYGGTSG
K
G
L
V
Q
A
T
K
HFGFV
P
T
H
LA
S
Q
S
A
I
V
E
A
L
Q
AG
H
H
V
L
A
A
V
Q
QDKFSPWGINYS
H
E
I
V
L
R
GYSNG
N
T
Y
V
YDPYNRANIGW
Y
P
V
A
N
L
W
N
E
QSRDAIDTSSVGV
P
F
F
K
I
T
T
Q
K
M
A
Q
L
E
A
Q
K
A
Q
V
Q
S
S
L
--
N
T
A
K
N
Q
L
A
K
T
Q
D
V
L
R
T
L
EATPLKT
P
E
A
Q
A
K
L
N
Q
A
K
E
A
L
A
L
A
Q
A
D
Y
T
K
A
Q
E
A
V
K
L
A
S
QDL
A
V
K
E
E
T
L
K
N
A
Q
A
D
L
L
T
K
Q
T
ALKDA
Q
T
V
L
V
A
-----
S
Q
V
K
L
A
D
L
K
A
T
L
A
T
V
ENN
V
K
K
A
Q
A
T
L
T
D
A
K
A
I
V
G
Q
K
Q
A
K
L
L
A
LQNA
P
K
I
L
ADAQ
A
K
L
V
T
A
K
N
D
L
A
N
K
M
A
I
L
D
E
A
V
A
K
L
K
S
L
Q
A
V
Q
A
E
A
Q
K
Q
Y
H
V
V
F
E
A
Y
K
A
V
R
D
A
K
E
Q
A
K
L
A
E
S
Y
N
H
I
I
ARGG
E
A
IPVVDETD
K
I
T
G
Y
VDGSQKAVA
N
E
V
T
L
A
L
TSNGAPLESPVNKENQNVTKSSQALPHTG
E
A
G
L
S
I
L
S
V
L
G
V
G
L
I
S
T
L
G
L
T
S
L
KKRRPH
5
PsiBlast_PDB
71.92
25%
72
- C4 -
4CGK
-
?
A:
[42-221]
---------------------------------------------
S
N
L
T
A
Q
Q
-
Q
E
A
Q
K
Q
V
D
Q
I
Q
E
Q
V
S
A
I
Q
A
E
Q
S
N
L
Q
A
E
N
D
R
L
Q
A
E
S
K
K
L
E
-
G
E
I
T
E
L
S
K
N
I
V
S
R
N
Q
S
L
E
K
Q
A
R
S
A
Q
T
N
G
--
A
V
T
S
Y
I
N
T
I
V
N
S
-
K
S
I
T
E
A
I
-
S
R
V
A
-
A
M
S
E
I
V
S
A
N
N
K
M
L
--
E
Q
Q
K
A
D
K
K
A
---------
I
S
E
K
Q
V
A
N
N
D
A
I
N
T
V
--
I
A
N
-
Q
--
Q
K
L
A
D
D
A
------
Q
A
L
T
T
K
Q
A
E
L
K
A
A
E
L
S
L
A
---
A
E
K
A
T
A
-
E
-
G
E
K
A
S
L
L
E
---
Q
K
A
A
A
-----------
E
A
E
A
R
A
A
A
V
--------
A
E
A
A
Y
K
E
K
R
A
S
Q
Q
Q
S
V
L
A
S
A
N
T
N
L
T
A
Q
V
Q
A
V
S
E
S
A
A
A
P
V
R
A
K
V
R
P
T
Y
S
T
N
A
S
S
Y
P
I
G
E
C
T
W
G
V
K
T
L
A
P
W
A
G
D
Y
W
G
N
G
A
Q
W
A
T
S
A
A
A
A
G
F
R
T
G
S
T
P
Q
V
G
A
I
A
C
W
N
D
G
G
Y
G
H
V
A
V
V
T
A
V
E
S
T
T
R
I
Q
V
S
E
S
N
Y
A
G
N
R
T
I
G
N
H
R
G
W
F
N
P
T
T
T
S
E
G
F
V
T
Y
I
Y
A
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
69.86
25%
115
- C4 -
2EFR
-
GCN4_YEAST (first)
A:
[183-301]
--------------------------------------------------------------------------------------------------------------------------------------
A
E
L
S
E
G
K
S
--
A
E
L
E
-
E
E
L
K
T
V
T
N
N
L
K
S
L
--
E
A
Q
A
E
K
Y
S
Q
---------
K
E
D
K
Y
E
E
E
I
K
V
L
S
D
K
L
K
E
A
E
-
T
--
R
A
-
E
F
A
E
------
R
S
V
T
K
L
E
K
S
I
D
D
L
E
D
E
L
Y
--
A
Q
K
L
K
Y
K
-
A
I
S
E
E
M
K
Q
L
E
D
K
V
E
E
L
L
S
-----------
K
N
Y
H
L
E
N
E
V
--------
A
R
L
K
K
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
69.72
25%
111
- C4 -
2EFS
-
GCN4_YEAST (first)
A:
[183-301]
--------------------------------------------------------------------------------------------------------------------------------------
A
E
L
S
E
G
K
S
--
A
E
L
E
-
E
E
L
K
T
V
T
N
N
L
K
S
L
--
E
A
Q
A
E
K
Y
S
Q
---------
K
E
D
K
Y
E
E
E
I
K
V
L
S
D
K
L
K
E
A
E
-
T
--
R
A
-
E
F
A
E
------
R
S
V
T
K
L
E
K
S
I
D
D
L
E
D
E
L
Y
--
A
Q
K
L
K
Y
K
-
A
I
S
E
E
M
K
Q
L
E
D
K
V
E
E
L
L
S
-----------
K
N
Y
H
L
E
N
E
V
--------
A
R
L
K
K
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
66.66
21%
88
- C4 -
2B5U
-
CEA3_ECOLX
A:
[241-450]
-----------
V
Q
T
L
S
P
G
V
T
N
N
T
D
K
D
V
R
P
A
G
F
T
Q
G
G
N
T
R
D
A
V
I
R
F
P
K
--
D
S
G
H
N
A
V
Y
V
S
V
S
D
V
L
S
P
D
Q
-----
V
K
Q
R
Q
D
E
E
N
R
R
Q
Q
E
W
-
D
A
T
-
H
P
V
E
A
A
E
R
N
Y
E
R
A
R
A
E
L
---------------
N
Q
A
N
E
D
V
A
R
N
Q
E
R
Q
A
K
A
V
-
Q
V
Y
N
-
S
R
K
S
E
L
D
A
A
N
K
T
L
--
A
D
A
I
A
E
I
K
Q
F
NRFAHDPM
A
G
G
H
R
M
W
Q
M
A
G
L
K
A
Q
--
R
A
Q
-
T
--
D
V
-
N
N
K
Q
------
A
A
F
D
A
A
A
K
E
K
S
D
A
D
A
A
L
S
--
S
A
M
E
S
R
K
-
K
K
E
D
K
K
R
S
A
E
---
N
N
L
N
D
-----------
E
K
N
K
P
R
K
G
F
--------
K
D
Y
G
H
D
Y
H
P
A
P
K
T
E
N
I
K
G
L
G
D
L
K
P
G
I
P
K
T
P
K
Q
N
G
G
G
K
R
K
R
W
T
G
D
K
G
R
K
I
Y
E
W
D
S
Q
H
G
E
L
E
G
Y
R
A
S
D
G
Q
H
L
G
S
F
D
P
K
T
G
N
Q
L
K
G
P
D
P
K
R
N
I
K
K
Y
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
64.56
12%
13
- C4 -
2YFA
4
MCPS_PSEPK
A:
[18-253]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
H
M
G
D
I
G
Q
L
N
K
D
L
T
D
L
R
I
A
R
L
Q
Y
M
I
A
N
G
D
D
T
A
A
A
N
T
L
A
K
L
D
A
F
S
K
Q
Q
A
Y
L
A
T
T
F
KS
P
E
N
V
K
L
L
G
E
L
G
D
T
I
S
A
Y
K
L
S
L
N
K
M
R
Q
G
Y
D
A
T
R
A
A
R
V
S
M
D
S
S
A
I
R
A
D
Q
A
M
D
A
L
S
Q
E
V
M
A
R
P
E
A
D
S
V
R
L
A
Q
Y
Q
L
I
S
K
A
R
Q
Q
L
L
Q
V
R
I
D
V
R
G
Y
I
A
E
N
S
S
A
N
E
Q
A
A
L
R
Q
L
D
A
A
L
A
D
T
D
N
L
K
R
Q
L
P
S
E
D
A
R
L
Q
Q
F
E
N
A
V
L
A
Y
R
D
A
V
R
Q
F
R
D
A
V
A
N
I
T
T
S
R
A
E
M
T
V
Q
G
A
D
I
V
K
R
S
D
A
L
Y
Q
I
Q
L
E
R
-------------------------------------------------------------------------------------------------------------------------------
30
Fugue
63.58
13%
121
- C4 -
2FXO
-
MYH7_HUMAN
A:
[-3-963]
---------------------------------------------------------------------------------------------------
P
L
L
K
S
A
E
R
E
K
E
M
A
S
M
K
E
E
F
T
R
L
K
E
A
L
E
K
S
E
A
R
R
K
E
L
E
E
K
M
V
S
L
L
-
Q
E
K
N
-
D
L
Q
L
Q
V
Q
A
E
Q
D
N
L
--
A
D
A
E
E
R
C
D
Q
---------
L
I
K
N
K
I
Q
L
E
A
K
V
K
E
M
--
N
K
R
-
L
--
E
D
-
E
E
E
M
------
N
A
E
L
T
A
K
K
R
K
L
E
D
E
C
S
E
L
--
K
R
D
I
D
D
L
-
E
L
T
L
A
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
63.47
21%
84
- C4 -
1JCH
1
CEA3_ECOLX
A:
[241-450]
-----------
V
Q
T
L
S
P
G
V
T
N
N
T
D
K
D
V
R
P
A
F
G
T
Q
G
G
N
T
R
D
A
V
I
R
F
P
K
--
D
S
G
H
N
A
V
Y
V
S
V
S
D
V
L
S
P
D
Q
-----
V
K
Q
R
Q
D
E
E
N
R
R
Q
Q
E
W
-
D
A
T
-
H
P
V
E
A
A
E
R
N
Y
E
R
A
R
A
E
L
---------------
N
Q
A
N
E
D
V
A
R
N
Q
E
R
Q
A
K
A
V
-
Q
V
Y
N
-
S
R
K
S
E
L
D
A
A
N
K
T
L
--
A
D
A
I
A
E
I
K
Q
F
NRFAHDPM
A
G
G
H
R
M
W
Q
M
A
G
L
K
A
Q
--
R
A
Q
-
T
--
D
V
-
N
N
K
Q
------
A
A
F
D
A
A
A
K
E
K
S
D
A
D
A
A
L
S
--
S
A
M
E
S
R
K
-
K
K
E
D
K
K
R
S
A
E
---
N
N
L
N
D
-----------
E
K
N
K
P
R
K
G
F
--------
K
D
Y
G
H
D
Y
H
P
A
P
K
T
E
N
I
K
G
L
G
D
L
K
P
G
I
P
K
T
P
K
Q
N
G
G
G
K
R
K
R
W
T
G
D
K
G
R
K
I
Y
E
W
D
S
Q
H
G
E
L
E
G
Y
R
A
S
D
G
Q
H
L
G
S
F
D
P
K
T
G
N
Q
L
K
G
P
D
P
K
R
N
I
K
K
Y
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
62.63
21%
71
- C4 -
1C1G
-
TPM1_PIG
A:
[68-257]
-------------------------------------------------
Q
E
K
L
E
L
A
E
K
K
A
T
D
A
E
A
D
V
A
S
L
N
R
R
I
Q
L
F
E
E
E
L
D
R
A
Q
E
R
L
A
T
A
L
-
Q
K
L
E
E
A
E
K
-
A
A
D
E
S
E
R
G
M
K
V
I
E
S
R
A
Q
K
D
E
E
K
M
E
I
Q
E
I
Q
L
K
E
A
K
H
I
A
E
D
A
D
-
R
K
Y
E
-
E
V
A
R
K
L
V
I
I
E
S
D
L
--
E
R
A
E
E
R
A
E
L
---------
S
E
G
K
C
A
E
L
E
E
E
I
K
T
V
--
T
N
N
-
L
--
K
S
-
L
E
A
Q
A
-----
E
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
--
D
K
L
K
E
A
E
-
T
R
A
E
---
F
A
E
---
R
S
V
T
K
-----------
L
E
K
S
I
D
D
L
E
--------
D
E
L
Y
A
Q
K
L
K
Y
K
A
I
S
E
E
L
D
H
A
L
N
D
M
T
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
58.14
23%
108
- C4 -
2PMS
1
?
C:
[4-125]
------------------------------------------------------------------------------------------------------------------------------------
M
D
A
E
E
V
A
P
Q
A
K
I
A
E
L
E
-
N
Q
V
H
R
L
E
Q
E
L
K
E
I
--
D
E
---------------------
A
P
L
Q
S
K
L
D
A
K
--
K
A
K
L
S
--
K
L
-
E
E
L
S
------
D
K
I
D
E
L
D
A
E
I
A
K
L
E
D
Q
L
K
--
A
A
E
E
-----
E
D
Y
F
K
E
G
L
E
---
K
T
I
A
A
-----------
K
K
A
E
L
E
K
T
E
--------
A
D
L
K
K
A
V
N
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
58.07
21%
99
- C4 -
3OJA
4
?
A:
[261-460]
--------------------------------------------------------------------
N
Q
R
V
Q
T
V
A
K
Q
T
V
K
K
L
T
G
Q
N
E
E
E
C
T
V
P
T
L
G
H
Y
G
A
Y
C
C
E
D
L
P
A
P
F
A
D
R
L
I
A
L
K
R
K
E
H
A
L
L
S
-----
T
E
R
L
E
C
E
R
E
-
N
-
Q
A
R
Q
-
R
E
I
D
A
L
K
E
Q
Y
R
T
V
--
I
D
Q
V
T
L
R
K
Q
---------
A
K
I
T
L
E
Q
K
K
K
A
L
D
E
Q
--
V
S
N
-
G
--
R
R
-
A
H
A
E
L
D
G
T
L
Q
Q
A
V
G
Q
I
E
L
Q
H
A
T
E
E
Q
S
P
L
--
Q
L
L
R
A
I
V
-
K
R
Y
E
E
M
Y
V
E
Q
---
Q
S
V
Q
N
N
A
I
R
D
W
D
M
Y
Q
H
K
E
T
Q
L
A
E
E
N
--------
A
R
L
K
K
L
N
G
E
A
D
L
A
L
A
S
A
N
A
T
L
Q
E
L
V
V
R
E
Q
N
L
A
S
Q
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
57.82
10%
22
- C4 -
1CII
-
?
?:
[23-624]
--------------------
E
I
M
A
V
D
I
Y
----
V
N
P
P
R
V
D
V
F
H
G
T
P
P
A
W
S
S
F
--
G
N
K
T
I
W
G
G
N
E
W
V
D
D
S
P
T
R
S
D
I
E
K
R
D
K
E
I
T
A
Y
K
N
T
L
S
A
Q
Q
-
K
E
N
E
N
K
R
T
E
A
G
K
R
L
S
A
A
I
A
A
R
E
K
D
E
N
T
L
K
T
L
R
A
G
N
A
D
A
A
D
I
T
R
Q
E
F
R
L
L
Q
-
A
E
L
R
-
E
Y
G
F
R
T
E
I
A
G
Y
D
A
--
L
R
L
H
T
E
S
R
M
---------
L
F
A
D
A
D
S
L
R
I
--
S
P
R
--
E
A
R
-
S
--
L
I
-
E
Q
A
E
------
K
R
Q
K
D
A
Q
N
A
D
K
K
A
A
D
M
L
A
--
E
Y
E
R
R
K
G
-
I
L
D
T
R
L
S
E
L
E
---
K
N
G
G
A
-----------
A
L
A
V
L
D
A
Q
Q
--------
A
R
L
L
G
Q
Q
T
R
N
D
R
A
I
S
E
A
R
N
K
L
S
S
V
T
E
S
L
N
T
A
R
N
A
L
T
R
A
E
Q
Q
L
T
Q
Q
K
N
T
P
D
G
K
T
I
V
S
P
----------------
E
K
F
P
G
R
S
S
T
N
D
S
I
V
V
S
G
D
P
R
F
A
G
T
I
K
I
T
T
S
A
V
I
D
N
R
A
N
L
N
Y
L
L
------------------------------------------------------------------------------
S
H
S
G
L
D
Y
K
R
N
I
L
N
D
R
N
--
P
V
V
T
E
D
V
E
G
D
K
K
I
Y
N
A
E
V
A
E
W
D
K
L
R
Q
R
L
L
D
A
R
N
K
I
T
S
A
E
S
A
V
N
S
A
R
N
N
L
S
A
R
T
N
E
Q
K
H
A
N
D
A
L
N
A
L
L
K
E
K
E
N
I
R
N
Q
L
S
G
I
N
Q
K
I
A
E
E
K
R
-----
K
Q
D
E
L
K
A
T
K
D
A
I
N
F
T
T
E
F
L
K
S
V
S
E
K
Y
G
A
K
A
E
Q
L
A
R
E
M
A
G
Q
A
K
G
K
K
I
R
N
-
V
E
E
A
L
K
T
Y
E
K
Y
R
A
D
I
N
K
K
I
N
A
K
D
R
A
A
I
A
A
A
L
E
S
V
K
L
S
D
I
S
S
N
L
N
R
F
S
R
G
L
G
Y
A
G
K
F
T
S
L
A
D
W
I
T
E
F
G
K
A
V
R
T
E
-
N
W
R
P
L
F
V
K
T
E
T
I
I
A
----
G
N
A
A
T
A
L
V
A
L
V
F
S
I
L
T
G
S
A
L
---------------------
G
I
I
G
Y
G
L
L
M
A
V
T
G
A
L
I
D
E
S
L
V
E
K
A
N
K
F
W
--
12
PsiBlast_PDB
56.92
24%
72
- C4 -
2W4U
-
TPM1_RABIT
A:
[61-268]
-------------------------------------------------
Q
E
K
L
E
L
A
E
K
K
A
T
D
A
E
A
D
V
A
S
L
N
R
R
I
Q
L
V
E
E
E
L
D
R
A
Q
E
R
L
A
T
A
L
-
Q
K
L
E
E
A
E
K
A
A
D
E
S
------
E
R
G
M
K
V
I
E
S
R
------------
A
Q
K
D
E
E
K
M
E
I
Q
E
I
Q
L
K
E
A
K
H
I
A
E
D
------
A
D
R
K
Y
E
E
V
A
---------
R
K
L
V
I
I
E
S
----
D
L
E
--
R
A
E
-
E
--
R
A
-
E
L
S
E
------
G
K
C
A
E
L
E
E
E
L
K
T
V
T
N
N
L
K
SL
E
A
Q
A
E
K
Y
-
S
Q
K
E
D
K
Y
E
E
E
---
I
K
V
L
S
-----------
D
K
L
K
E
A
E
T
R
AEFAERSV
T
K
L
E
K
S
I
D
D
L
E
D
E
L
Y
A
Q
K
L
K
Y
K
A
I
S
E
E
L
D
H
A
L
N
D
M
T
S
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
55.94
21%
183
- C- -
2TMA
-
TPM1_RABIT
A:
[68-257]
-------------------------------------------------
Q
E
K
L
E
L
A
E
K
K
A
T
D
A
E
A
D
V
A
S
L
N
R
R
I
Q
L
V
E
E
E
L
D
R
A
Q
E
R
L
A
T
A
L
-
Q
K
L
E
E
A
E
K
-
A
A
D
E
S
E
R
G
M
K
V
I
E
S
R
A
Q
K
D
E
E
K
M
E
I
Q
E
I
Q
L
K
E
A
K
H
I
A
E
D
A
D
-
R
K
Y
E
-
E
V
A
R
K
L
V
I
I
E
S
D
L
--
E
R
A
E
E
R
A
E
L
---------
S
E
G
K
C
A
E
L
E
E
E
I
K
T
V
--
T
N
N
-
L
--
K
S
-
L
E
A
Q
A
-----
E
K
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
S
--
D
K
L
K
E
A
E
-
T
R
A
E
---
F
A
E
---
R
S
V
T
K
-----------
L
E
K
S
I
D
D
L
E
--------
D
E
L
Y
A
Q
K
L
K
Y
K
A
I
S
E
E
L
D
H
A
L
N
D
M
T
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
55.39
33%
169
- C4 -
2ZDI
1
PFDB_PYRHO
B:
[31-107]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
Q
--
A
D
L
N
E
A
K
K
A
---------
L
E
E
I
E
T
L
P
D
D
A
Q
I
Y
K
--
T
V
G
-
T
LI
V
K
-
T
T
K
E
------
K
A
V
Q
E
L
K
E
K
I
E
T
L
E
V
R
L
N
--
A
L
N
R
Q
E
Q
-
K
I
N
E
K
V
K
E
L
T
---
Q
K
I
Q
A
-----------
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
54.30
12%
131
- C4 -
3U0C
-
IPAB_SHIFL
A:
[136-201]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
E
K
Q
I
N
K
L
K
N
A
D
S
K
I
K
D
L
E
N
K
I
N
Q
I
Q
T
R
L
S
E
L
D
P
E
S
P
E
K
K
K
L
S
R
E
E
I
Q
L
T
I
K
K
D
A
A
V
K
D
R
T
L
I
E
Q
----------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
54.17
21%
128
- C4 -
3TUL
-
SIPB_SALTY
A:
[137-207]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
A
T
D
L
Y
E
A
S
I
K
K
T
D
T
A
K
S
V
Y
D
A
A
T
K
K
L
T
Q
A
Q
N
K
L
Q
S
L
-------
A
Q
A
E
A
A
V
E
Q
A
G
K
E
A
T
E
A
K
E
A
L
D
K
A
T
D
----------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
54.14
26%
97
- C4 -
4NC3
2
A:
[220-347]
-------------------------------------------------------------------------------------------------------------------------------------------
Q
K
K
A
-
A
D
L
E
-
D
N
W
E
T
L
N
D
N
L
K
V
I
E
K
A
D
N
A
A
Q
V
K
D
---------
A
L
T
K
M
R
A
--------------------------------------
K
D
F
R
H
G
F
D
I
L
--
V
G
Q
I
D
D
A
L
K
L
A
N
E
G
K
V
K
E
---
A
Q
A
A
A
-----------
E
Q
L
K
T
T
R
N
A
--------
Y
I
Q
K
Y
L
Q
T
-
I
S
N
E
Q
R
A
S
K
V
L
G
I
V
F
F
L
F
L
L
M
W
C
P
F
F
I
T
N
I
T
L
V
L
C
D
S
C
N
Q
T
T
L
Q
M
L
L
E
I
F
V
W
I
G
Y
V
S
S
G
V
N
P
L
V
Y
T
L
F
N
K
T
F
R
D
A
F
G
R
Y
I
T
C
N
Y
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
54.05
19%
133
* C4 *
1NYH
-
SIR4_YEAST
A:
[1271-1346]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
F
V
D
I
V
L
S
K
A
A
S
A
L
D
E
K
E
K
Q
L
A
V
A
N
E
I
I
R
S
L
S
D
E
V
M
R
N
E
I
R
I
T
S
L
Q
G
D
L
T
F
T
K
K
C
L
E
N
A
R
S
Q
I
S
E
-----
K
D
A
K
I
N
K
L
M
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
53.53
22%
123
- C4 -
1UJW
-
B:
[10-125]
---------------------------------------------------------------------------------------------------------------------
Y
E
R
A
R
A
E
L
N
Q
A
N
E
D
V
A
R
N
Q
E
R
Q
A
K
A
V
-
Q
V
Y
N
-
S
R
K
S
E
L
D
A
A
N
K
T
L
--
A
D
A
I
A
E
I
K
Q
F
NRFAHDPM
A
G
G
H
R
M
W
Q
M
A
G
L
K
A
Q
--
R
A
Q
-
T
--
D
V
-
N
N
K
Q
------
A
A
F
D
A
A
A
K
E
K
S
D
A
D
A
A
L
S
--
S
A
M
E
S
R
K
-
K
K
E
D
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
53.39
33%
175
- C4 -
2ZDI
1
PFDB_PYRHO
A:
[31-107]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
Q
--
A
D
L
N
E
A
K
K
A
---------
L
E
E
I
E
T
L
P
D
D
A
Q
I
Y
K
--
T
V
G
-
T
LI
V
K
-
T
T
K
E
------
K
A
V
Q
E
L
K
E
K
I
E
T
L
E
V
R
L
N
--
A
L
N
R
Q
E
Q
-
K
I
N
E
K
V
K
E
L
T
---
Q
K
I
Q
A
-----------
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------