@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0419: (2015-11-30 )
MKPSFKKLLLLFSIITILSIACTPHAKASGRSWKSWFIEQYFWLKRDKSYYKVQDESSFQKYLNASREQSDKGYYLDPNSVNGGLVQERLFDMQVYSWNDNGKANQKTIFYLAGGSYLNNPTPYHISMLKTLSTSLDAKIILPIYPKTPRYTYDYAIPRLVNLYRHFHEKNANLTLMGDSAGGGLALGLAHALSHQSGQEAIPQPKNIILLSPWLDVTMKHPEIPKYEDTDPILSAWGLARVGEIWANGSNNTNHTYVSPKNAPATKLAPITLFTGTREIFFPDIRDYAAQLQAANHPVNYIAQEGMNHVYPIYPIEEAKTAQYQMIDIINKTP
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80.--.......90........100-.......110.......120.......130.....-..140.......150.......160...----....---170-----.........180.......190.......200.......210.......220.--...-...230.......240.......250.......260.-......270.......280.......290.......300.......310--.----....--.--...320.......330..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKP
S
F
K
K
L
L
L
L
F
S
I
I
T
I
L
S
IACTPHAKASG
R
S
W
K
S
W
F
I
E
Q
Y
F
W
L
KRDK
S
Y
Y
K
VQ
D
E
S
S
F
Q
K
Y
L
N
ASREQSDK
G
Y
YLDPNSVN--
G
G
L
V
Q
E
R
L
F
D
M
Q
V
Y
S
WNDNG-KAN
Q
K
T
I
F
Y
LAGGSYLNNPT
P
Y
H
I
S
M
L
K
T
L
STSLD-
A
K
I
I
L
P
IYPKTP
R
Y
TYD
Y
A
I
P
R
L
V
N
L
Y
R
----
H
F
H
E---K-------NA
N
L
T
L
M
GDSAG
G
G
L
A
L
G
L
A
H
A
L
SHQSGQEAIPQPK
N
I
I
L
LSPWL
D
V
TMKHPE--IPK-YEDT
D
P
I
L
S
A
W
G
L
A
R
V
G
E
I
W
ANGSNNT
N
H
T
Y
VSPKNA-PATK
L
A
P
I
T
L
F
TGTREIFFP
D
I
R
D
Y
A
A
Q
L
QAANH
P
V
N
Y
I
A
Q
EGMNHV----Y----PIYP--I--EEAKTA
Q
Y
Q
M
I
D
I
INKTP
31
HHSearch
95.34
31%
-96
- C1 -
3D7R
11
?
A:
[75-321]
-------------------------------------------------------------------------------------
N
L
E
K
L
S
L
D
D
M
Q
V
F
R
F
N
F
R
H
--
Q
I
D
K
K
I
L
Y
I
H
G
G
F
N
A
L
Q
P
S
P
F
H
W
R
L
L
D
K
I
T
L
S
T
L
-
Y
E
V
V
L
P
I
Y
P
K
T
P
E
F
H
I
D
D
T
F
Q
A
I
Q
R
V
Y
D
----
Q
L
V
S
---
E
VG-----
H
Q
N
V
V
V
M
G
D
G
S
G
G
A
L
A
L
S
F
V
Q
S
L
L
D
----
N
Q
Q
P
L
P
N
K
L
Y
L
I
S
P
I
L
D
A
T
L
S
N
K
D
--
I
S
D
A
L
I
E
Q
D
A
V
L
S
Q
F
G
V
N
E
I
M
K
K
W
A
N
G
L
-
P
L
T
D
K
R
I
S
P
I
N
G
-
T
I
E
G
L
P
P
V
Y
M
F
G
G
G
R
E
M
T
H
P
D
M
K
L
F
E
Q
M
M
L
Q
H
H
Q
Y
I
E
F
Y
D
Y
P
K
M
V
H
D
----
F
----
P
I
Y
P
--
I
--
R
Q
S
H
K
A
I
K
Q
I
A
K
S
I
D
E
D
V
32
HHSearch
82.52
25%
-83
- C1 -
3FAK
1
?
A:
[56-307]
---------------------------------------------------------------------------------
D
--
I
Q
V
E
Q
V
T
V
A
G
C
A
A
E
W
V
R
A
P
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
---
Q
GFK----
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
A
V
L
V
S
A
R
D
----
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
V
A
P
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
----
W
----
H
A
F
H
PM
L
--
P
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
1
PsiBlast_PDB
82.11
27%
-72
- C1 -
3D7R
12
?
A:
[56-320]
------------------------------------------------------------------
R
E
I
E
N
R
K
K
H
K
Q
P
S
T
L
N
VK
A
N
L
E
K
L
S
L
D
D
M
Q
V
F
R
F
N
F
R
H
-
Q
I
D
K
K
-
I
L
Y
I
H
G
G
F
N
A
L
Q
P
S
P
F
H
W
R
L
L
D
K
I
T
L
S
T
L
-
Y
E
V
V
L
P
I
Y
P
K
T
P
E
F
H
I
D
D
T
F
Q
A
I
Q
R
V
Y
D
----
Q
L
V
S
---
E
-------
V
G
H
Q
N
V
V
V
M
G
D
G
S
G
G
A
L
A
L
S
F
V
Q
S
L
L
D
N
Q
Q
--
P
L
P
N
K
L
Y
L
I
S
P
I
L
D
A
T
L
S
N
K
D
--
I
S
D
A
L
I
E
Q
D
A
V
L
S
Q
F
G
V
N
E
I
M
K
K
W
A
N
G
L
P
L
T
D
-
K
R
I
S
P
I
N
G
-
T
I
E
G
L
P
P
V
Y
M
F
G
G
G
R
E
M
T
H
P
D
M
K
L
F
E
Q
M
M
L
Q
H
H
Q
Y
I
E
F
Y
D
Y
P
K
M
V
H
D
----
F
----
P
I
Y
P
--
I
--
R
Q
S
H
K
A
I
K
Q
I
A
K
S
I
D
E
D
V
33
HHSearch
81.22
22%
-93
- C1 -
3K6K
3
?
A:
[58-307]
------------------------------------------------------------------------------------
V
E
L
T
L
T
D
L
G
G
V
P
C
I
R
Q
A
T
D
G
--
A
G
A
A
H
I
L
Y
F
H
G
G
G
Y
I
S
G
S
P
S
T
H
L
V
L
T
T
Q
L
A
K
Q
S
S
-
A
T
L
W
S
L
D
Y
R
L
A
P
E
N
P
F
P
A
A
V
D
D
C
V
A
A
Y
R
----
A
L
L
K
---
T
A
GS----
A
D
R
I
I
I
A
G
D
S
A
G
G
G
L
T
T
A
S
M
L
K
A
K
E
----
D
G
L
P
M
P
A
G
L
V
M
L
S
P
F
V
D
L
T
L
S
R
W
S
--
N
S
N
-
L
A
D
R
D
F
L
A
E
P
D
T
L
G
E
M
S
E
L
Y
V
G
G
E
-
D
R
K
N
P
L
I
S
P
V
Y
A
-
D
L
S
G
L
P
E
M
L
I
H
V
G
S
E
E
A
L
L
S
D
S
T
T
L
A
E
R
A
G
A
A
G
V
S
V
E
L
K
I
W
P
D
M
P
H
V
----
F
----
Q
M
Y
G
--
K
FV
N
A
A
D
I
S
I
K
E
I
C
H
W
I
S
A
R
I
17
PsiBlast_PDB
76.46
24%
-81
- C1 -
4XVC
1
?
A:
[84-314]
-------------------------------------------------------------------------------------------------------
G
-
A
R
D
D
Q
V
F
L
Y
L
H
G
G
G
Y
V
I
G
S
M
R
T
H
R
V
M
L
S
H
I
A
R
A
A
G
-
C
R
V
L
G
L
D
Y
R
L
A
P
E
T
P
F
P
A
P
V
E
D
T
V
A
A
Y
R
W
L
L
A
H
G
Y
D
---
P
-------
S
-
R
I
A
L
G
G
D
S
A
G
G
G
L
V
V
A
A
L
V
A
L
R
Y
I
G
E
----
P
L
P
A
A
G
V
C
L
S
P
W
I
D
M
E
A
T
G
E
S
--
F
T
T
-
N
A
T
M
D
P
S
V
N
K
E
R
V
M
S
I
A
A
L
Y
L
G
G
-
K
N
P
Q
A
P
L
A
S
P
L
Y
A
-
D
L
Q
G
L
P
P
L
L
V
Q
V
G
G
I
E
T
L
L
D
D
A
R
A
L
T
T
R
A
K
A
A
G
V
D
A
D
L
E
V
W
D
D
M
P
H
V
----
W
QHFA
P
I
L
P
------
E
G
K
Q
A
I
A
R
I
G
E
F
L
R
K
Q
I
35
HHSearch
75.53
20%
-89
- C1 -
3WJ2
-
?
A:
[61-308]
------------------------------------------------------------------------------------------
D
G
R
T
L
N
A
R
M
Y
D
D
N
---
N
A
K
S
A
I
L
Y
Y
H
G
G
G
F
L
F
G
N
I
E
T
Y
D
N
Y
C
R
F
L
A
K
E
S
G
-
V
K
I
I
S
I
E
Y
R
L
A
P
E
H
K
F
P
D
A
F
N
D
A
Y
D
S
F
H
----
Y
I
A
K
---
K
KKDFGI-
E
G
R
I
G
V
A
G
D
S
A
G
A
N
L
A
A
A
L
C
L
K
C
R
D
----
G
K
T
E
M
P
A
V
Q
V
L
F
Y
P
S
L
A
P
D
N
F
S
R
S
--
F
I
E
-
Y
S
-
D
N
Y
V
L
T
G
K
M
I
R
Y
F
G
N
M
Y
S
K
N
----
I
N
P
Y
F
S
P
L
V
A
D
D
F
S
N
L
P
P
A
I
M
V
T
N
E
Y
D
P
L
R
D
P
E
E
T
Y
V
K
K
L
R
E
A
G
V
R
A
V
G
I
R
G
I
G
M
I
H
G
----
S
----
A
T
D
F
--
E
VS
D
G
A
R
N
I
V
K
M
V
A
R
I
I
P
D
Y
L
34
HHSearch
74.05
18%
-93
* C1 *
3WJ1
1
?
A:
[56-300]
--------------------------------------------------------------------------------------------
T
S
I
N
A
R
V
Y
F
P
K
A
-
K
G
P
Y
G
V
L
V
Y
L
H
G
G
G
F
V
I
G
D
V
E
S
Y
D
P
L
C
R
A
I
T
N
A
C
N
-
C
V
V
V
S
V
D
Y
R
L
A
P
E
Y
K
F
P
S
A
V
I
D
S
F
D
A
T
N
----
W
I
Y
N
---
N
LDKFDG-
E
M
G
I
A
I
A
G
D
S
A
G
G
N
L
A
A
V
V
A
L
L
S
K
G
------
K
L
D
L
K
Y
Q
I
L
I
Y
P
A
V
G
F
D
S
V
S
R
S
--
M
I
E
-
Y
-
S
D
G
F
F
L
T
R
E
H
I
E
W
F
G
S
Q
Y
L
R
S
P
A
D
L
L
D
F
R
F
S
P
I
I
A
Q
D
L
S
G
L
P
P
A
L
I
I
T
A
E
Y
D
P
L
R
D
Q
G
E
A
Y
A
N
R
L
L
Q
A
G
V
P
V
T
S
V
R
F
N
N
V
I
H
G
----
F
----
L
S
F
F
PL
I
--
D
Q
G
K
D
A
I
G
L
I
G
S
V
L
R
R
T
F
8
PsiBlast_PDB
72.90
28%
-78
- C1 -
3H18
2
?
A:
[76-296]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
---
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
6
PsiBlast_PDB
72.80
28%
-76
- C1 -
3G9Z
-
?
A:
[63-283]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
V
A
P
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
44
HHSearch
72.44
19%
-88
- C1 -
2HM7
1
?
A:
[56-308]
------------------------------------------------------------------------------------------
P
G
R
T
L
K
V
R
M
Y
R
P
E
G
V
E
P
P
Y
P
A
L
V
Y
Y
H
G
G
S
W
V
V
G
D
L
E
T
H
D
P
V
C
R
V
L
A
K
-
D
G
R
A
V
V
F
S
V
D
Y
R
L
A
P
E
H
K
F
P
A
A
V
E
D
A
Y
D
A
L
Q
----
W
I
A
E
---
R
A
ADFHLD
P
A
R
I
A
V
G
G
D
S
A
G
G
N
L
A
A
V
T
S
I
L
A
K
E
----
R
G
G
P
A
L
A
F
Q
L
L
I
Y
P
S
T
G
Y
D
P
A
H
P
P
A
S
I
E
E
-
N
A
-
E
G
Y
L
L
T
G
G
M
M
L
W
F
R
D
Q
Y
L
N
S
L
E
E
L
T
H
P
W
F
S
P
V
L
Y
P
D
L
S
G
L
P
P
A
Y
I
A
T
A
Q
Y
D
P
L
R
D
V
G
K
L
Y
A
E
A
L
N
K
A
G
V
K
V
E
I
E
N
F
E
D
L
I
H
G
----
F
----
A
Q
F
Y
--
S
LS
P
G
A
T
K
A
L
V
R
I
A
E
K
L
R
D
A
L
9
PsiBlast_PDB
72.24
28%
-78
- C1 -
3H19
-
?
A:
[63-283]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
---
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
12
PsiBlast_PDB
71.75
28%
-78
- C1 -
3L1H
-
?
A:
[63-283]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
---
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
13
PsiBlast_PDB
71.20
28%
-72
- C1 -
3L1I
-
?
A:
[63-283]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
---
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
7
PsiBlast_PDB
71.15
28%
-77
- C1 -
3H17
1
?
A:
[76-296]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
----
P
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
3
PsiBlast_PDB
71.05
28%
-74
- C1 -
3FAK
1
?
A:
[76-296]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
V
A
P
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
4
PsiBlast_PDB
70.93
28%
-76
- C1 -
3G9T
-
?
A:
[63-283]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
--
P
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
10
PsiBlast_PDB
70.78
28%
-76
- C1 -
3H1A
-
?
A:
[63-283]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
V
A
P
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
11
PsiBlast_PDB
69.11
28%
-75
- C1 -
3H1B
-
?
A:
[63-283]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
V
A
P
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
14
PsiBlast_PDB
68.98
28%
-72
- C1 -
3L1J
-
?
A:
[63-283]
-------------------------------------------------------------------------------------------------------
G
-
C
Q
A
G
K
A
I
L
Y
L
H
G
G
G
Y
V
M
G
S
I
N
T
H
R
S
M
V
G
E
I
S
R
A
S
Q
-
A
A
A
L
L
L
D
Y
R
L
A
P
E
H
P
F
P
A
A
V
E
D
G
V
A
A
Y
R
----
W
L
L
D
Q
GF
K
-------
P
Q
H
L
S
I
S
G
D
S
A
G
G
G
L
V
L
----
A
V
L
V
S
A
R
D
Q
G
L
P
M
P
A
S
A
I
P
I
S
P
W
A
D
M
T
C
T
N
D
S
--
F
K
T
-
R
A
E
A
D
P
M
---
G
G
I
N
K
M
A
A
R
Y
L
N
G
A
-
D
A
K
H
P
Y
A
S
P
N
F
A
-
N
L
K
G
L
P
P
L
L
I
H
V
G
R
D
E
V
L
L
D
D
S
I
K
L
D
A
K
A
K
A
D
G
V
K
S
T
L
E
I
W
D
D
M
I
H
V
WHAF
H
----
P
M
L
P
------
E
G
K
Q
A
I
V
R
V
G
E
F
M
R
E
Q
W
37
HHSearch
68.96
17%
-88
- C1 -
1JJI
1
?
A:
[66-310]
--------------------------------------------------------------------------------------------
G
D
I
R
V
R
V
Y
Q
Q
K
P
---
D
S
P
V
L
V
Y
Y
H
G
G
G
F
V
I
C
S
I
E
S
H
D
A
L
C
R
R
I
A
R
L
S
N
-
S
T
V
V
S
V
D
Y
R
L
A
P
E
H
K
F
P
A
A
V
Y
D
C
Y
D
A
T
K
----
W
V
A
E
---
N
A
EELRID
P
S
K
I
F
V
G
G
D
S
A
G
G
N
L
A
A
A
V
S
I
M
A
R
D
----
S
G
E
D
F
I
K
H
Q
I
L
I
Y
P
V
V
N
F
V
A
P
T
P
S
--
L
L
E
-
F
G
E
G
L
W
I
L
D
Q
K
I
M
S
W
F
S
E
Q
Y
F
S
R
E
E
D
K
F
N
P
L
A
S
V
I
F
A
-
D
L
E
N
L
P
P
A
L
I
I
T
A
E
Y
D
P
L
R
D
E
G
E
V
F
G
Q
M
L
R
R
A
G
V
E
A
S
I
V
R
Y
R
G
V
L
H
G
----
F
----
I
N
Y
Y
--
P
VL
K
A
A
R
D
A
I
N
Q
I
A
A
L
L
V
F
D
-