@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0428: (2015-11-30 )
MKISQYNKWSIRRLKVGAASVMIASGSIVALGQSHIVSADEMSQPKTTITAPTANTSTNVESSTDKALSKVTTMETSSEMPKMQNMAKVEKTSDKPMMVATSVRKMMATPTPVAMTKTTSVDEVKKSTDTAFKQTVDVPAHYVNAAKGNGPFLAGVNQTIPYEAFGGDGMLTRLILKSSEGAKWSDNGVDKNSPLLPLKGLTKGKYFYQVSLNGNTTGKEGQALLDQIKANDKHSYQATIRVYGAKDGKVDLKNMISQKMVTINIPHITTDMEVKNSLKMAFKEKVDVPAKYVSAAKAKGPFLAGVNETIPYEAFGGDGMLTRLILKASEGAKWSDNGVDKNSPLLPLKDLTKGKYFYQVSLNGNTAGKKGQALLDQIKANGSHTYQATITIYGTKDGKVDMNTILGQKTVMIHINVAKKDMNSTSMMMKKDKMTMPMKKEMTSSKINTGMMMSNNKMSANMQMSSQAKSNDKAGKKMSMMSKNLPNTGETKQQNVGVLGMLSLAFATGLTALGLKKSKQR
Atome Classification :
(20 SA)
--------------------------------....--.....10........20.--..-----------.....-----30........40........50........60........70----.........80........90........100-------.......110.......120.......130.-----......140.......150.......160.......170........180......---------.190.......----200.......210.......220.......230.--......240.......250.......260---.......270.......280.......290.---..--...-.300-......---.310.......320.......330-------........340.---...-...350.....-------.---.360-----......-.370.......380.......390.---......400....----..-.410----.........420.........430------------.......440.-......450.......460.......470.......480.......490..---------------.....-------500.......510.......520---------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------MKIS--QYNK
W
S
I
R
R
L
KVG
A
A
S
V
M
--
I
A-----------S
G
S
I
V
-----
A
LGQSHIV
S
A
D
EMSQPK
T
T
I
TAPTANTSTNVES
S
T
D
K
A
L
S
K
-----VTTMETSSE
M
P
K
M
Q
N
M
A
K
V
EKTSDK
P
M
M
V
A
T
S
-------
V
R
K
M
MATPTP
V
A
M
TKTT
S
V
D
E
V
K
K
ST
D
T
A
F
K
-----
Q
TVDV
P
A
H
Y
V
NAAKGNG
P
F
L
AGVNQT
I
P
YEAFGGD
G
M
-
L
T
R
L
I
L
KSSEGAKWSDNG---------VDKNSPLLPLK----GLTK
G
K
Y
F
Y
Q
V
S
LNGNTTGK
E
G
Q
A
L
L
D
Q
I
KANDK--H
S
Y
Q
A
T
I
R
V
Y
GAKDGKV
D
L
K
N
M
ISQ
K
M
V
T
---
I
NIPHITT
D
M
E
V
K
N
S
L
K
M
A
F
K
EKVDV
P
A
K
Y
V
---
S
A
--AKA-KG
P
F
-LAGVNE---TIPYEAFGG
D
G
M
L
T
R
L
I
LKASEG--------AKWSDNGVDKNS---PLL-
P
L
K
DLTKG
K
Y
F
-------
Y
---
Q
V
S
L-----NGNTAG-K
K
G
Q
A
L
L
D
Q
I
KANGS
H
T
Y
Q
A
T
I
T
I
Y
---GTKDG
K
V
D
M
N
T
IL----GQ-
K
T
------
V
M
I
H
I
N
VAKK--DMN
S
T
S
M
M
M
KKD------------KMTM
P
M
K
K
E
M
T
-SSKINT
G
M
M
MSNNKMSAN
M
Q
MSSQAKSNDKAG
K
K
M
S
M
M
S
KNLPNTGET
K
Q
Q---------------N
V
G
V
L
-------
G
M
L
S
L
A
F
A
T
G
L
T
A
LGLKKSKQR----------------------------------------------------------------------------------------------------------
30
Fugue
82.38
20%
19
- C6 -
1CJD
-
CAPSD_BPPRD
A:
[15-383]
--------------------------------
L
R
N
Q
--
Q
A
M
A
A
N
L
Q
A
R
Q
I
V
L
Q
Q
-----------------------------------
S
Y
P
V
I
Q
Q
V
E
T
Q
T
F
D
P
A
N
R
S
V
F
D
V
T
P
A
-
N
V
G
I
V
K
-----
G
F
L
V
K
V
T
A
A
I
T
N
N
H
A
T
E
A
V
A
L
T
D
F
G
P
A
N
L
V
Q
R
-------
V
I
Y
Y
--
D
P
D
N
Q
R
H
T
E
T
S
----------------------
G
W
H
L
H
F
V
N
T
A
K
Q
G
A
P
F
L
S
S
M
V
T
D
S
P
I
K
Y
--
G
D
V
M
------------------
N
---------
V
I
D
A
P
A
T
I
A
A
G
----
A
T
G
E
L
T
M
Y
Y
W
V
P
L
A
Y
S
E
T
D
L
T
G
----------------------------------------
A
V
L
---
A
N
V
P
Q
------
S
K
Q
R
L
K
L
E
F
-------
A
N
N
N
---
T
A
--
F
A
A
-
V
G
A
N
P
L
E
A
I
Y
Q
---
G
A
G
A
A
D
C
E
F
E
E
I
S
Y
T
V
Y
Q
S
Y
L
D
Q
--------
L
P
V
G
Q
N
G
Y
--------
I
L
-
P
L
I
D
L
S
T
L
Y
N
L
-------
E
---
N
S
A
Q
-----
A
G
L
T
P
N
-
V
D
-----
F
V
V
Q
Y
A
N
L
Y
R
Y
L
S
T
I
A
V
F
DNG
G
S
F
N
A
G
T
D
I
N
Y
-
L
----
S
Q
-
R
T
---------------
A
--
N
F
S
D
T
R
---
K
L
D
------------
P
K
T
W
A
A
Q
T
R
R
R
I
A
T
D
F
P
K
G
V
Y
Y
C
D
N
R
-----------------
D
K
P
I
Y
T
L
Q
Y
G
-------------------------
N
V
G
F
V
-------
V
N
P
K
T
V
N
Q
N
A
R
L
L
M
G
Y
E
Y
F
T
S
R
----------------------------------------------------------------------------------------------------------
37
Fugue
80.66
15%
13
- C2 -
3WOL
10
DAPB2_PSEMX
A:
[1-696]
----------------GEGMWVPQQLPEI
A
G
P
L
K
K
A
GL
K
L
S
P
Q
Q
I
S
D
L
T
G
D
P
M
G
A
V
--
V
A
LGG
C
T
A
S
F
VSP
N
G
L
V
V
T
N
HHC
A
Y
G
A
I
Q
L
N
S
T
A
E
N
N
L
I
K
N
G
F
N
A
P
T
--
T
A
D
E
V
S
A
G
P
N
A
R
V
F
V
-----
L
D
E
I
T
D
V
T
K
D
A
K
A
A
I
A
A
A
G
D
D
A
L
A
R
T
K
A
L
E
A
F
-------
E
K
K
L
I
A
D
C
E
A
E
A
G
F
R
C
R
L
Y
S
F
S
G
G
N
T
Y
R
L
F
K
-----
N
L
E
I
K
D
V
R
L
A
Y
A
P
P
G
S
V
G
K
F
G
G
D
I
D
N
W
M
W
P
R
H
T
G
D
F
A
-
F
Y
R
A
Y
V
G
K
D
G
K
P
A
A
F
S
K
D
---------
N
V
P
Y
Q
P
K
H
W
L
K
F
A
D
Q
P
L
G
A
G
D
F
V
M
V
A
G
Y
P
G
S
T
N
R
Y
---
A
L
A
A
E
F
D
N
T
A
Q
--
W
T
Y
P
T
I
A
R
H
Y
K
N
Q
I
A
M
V
E
A
A
G
K
Q
N
A
D
I
Q
V
K
Y
A
A
T
M
A
G
W
N
N
T
S
K
N
Y
D
G
Q
L
E
G
F
K
R
I
-
D
A
A
G
Q
K
L
---
R
E
--
E
A
A
-
V
L
G
W
-
L
K
G
Q
G
---------
A
K
G
Q
P
A
L
D
A
H
A
K
L
L
D
L
L
E
--------
Q
S
K
A
T
R
D
R
D
L
T
L
---
A
L
F
N
N
T
A
M
L
G
S
A
T
Q
L
-------
Y
---
R
L
S
I
E
R
E
K
P
N
A
E
R
E
S
-
G
Y
Q
E
R
D
L
P
A
I
E
G
G
L
K
Q
L
E
R
R
Y
V
A
A
M
---
D
R
Q
L
Q
E
Y
W
L
N
E
Y
I
K
LPA
D
Q
-
R
V
------
A
A
V
D
A
W
L
G
G
N
--
D
A
A
A
V
K
R
A
L
D
R
L
A
G
TKLGS
T
E
E
R
L
K
W
F
A
A
D
R
K
A
F
E
-
A
S
N
-
D
P
A
I
Q
Y
A
V
A
V
M
P
T
L
L
K
L
E
Q
E
R
K
T
--
R
A
G
E
N
L
A
A
R
P
V
Y
L
Q
A
L
A
D
Y
K
K
S
Q
G
E
F
V
Y
P
DANL
S
L
R
I
T
F
G
N
V
M
G
Y
A
PKD
G
M
E
Y
T
P
F
T
T
-
L
E
G
V
V
A
K
E
T
G
Q
D
PFDSP
K
A
L
L
D
A
V
A
A
KRYGGLEDKRIGSVPV
N
Y
L
S
D
L
D
I
T
GGNSG
S
P
V
L
D
AHGKLV
G
L
A
F
DGNWESVSSNWVFDPKM
T
R
M
I
A
V
D
G
R
Y
L
R
W
I
M
Q
EVYPA
P
Q
L
L
K
E
M
NV
29
Fugue
77.98
14%
33
- C6 -
4MT0
1
?
A:
[1-445]
-------------------------------C
T
M
I
P
--
Q
Y
E
Q
P
K
V
E
V
A
E
T
F
Q
N
D
T
S
--
V
S
-----------
S
I
R
A
V
-----
D
L
G
W
H
D
Y
F
A
D
P
R
L
Q
K
L
I
D
I
A
L
E
R
--
N
T
S
L
R
T
A
V
L
N
S
E
I
Y
R
K
-----
Q
Y
M
I
E
R
N
N
L
L
P
T
L
A
A
N
A
N
G
S
R
Q
G
S
L
S
---
G
G
N
-------
V
S
S
S
Y
N
V
G
L
G
A
A
S
Y
E
L
D
L
F
G
R
V
R
S
S
S
E
A
A
L
Q
-----
G
Y
F
---
A
S
V
A
N
R
D
A
A
H
L
S
L
I
A
T
V
A
K
A
Y
F
N
E
R
Y
A
E
E
A
M
S
L
A
Q
R
V
L
K
T
R
E
E
T
Y
-----------------------------------
N
A
V
R
I
A
V
Q
G
R
R
D
F
R
R
R
P
A
P
A
E
A
L
I
E
S
A
K
--
A
D
Y
A
H
A
A
R
--
S
R
E
Q
A
R
N
A
L
A
T
L
I
N
R
P
-----------
I
P
E
D
L
P
A
G
L
P
L
D
K
Q
F
F
V
E
-
K
L
P
A
G
L
S
---
S
E
--
V
L
L
-
D
R
P
D
-
I
R
A
A
E
H
---
A
L
K
Q
A
N
A
N
I
G
A
A
-----------------------------
R
A
---
A
F
F
-
P
S
I
R
L
T
G
S
V
G
T
-------
G
---
S
V
E
L
-----
G
G
L
F
K
S
-
G
T
G
V
W
A
F
A
P
S
I
T
L
P
I
F
T
W
G
T
N
K
A
N
L
---
D
V
A
K
L
R
Q
Q
A
Q
I
V
A
----
Y
E
-
S
A
------
V
Q
S
A
F
Q
D
V
A
N
--
A
L
A
A
R
E
Q
L
D
K
A
Y
------------
D
A
L
S
K
Q
S
R
A
S
K
-
E
A
L
R
L
V
G
L
R
Y
K
H
G
V
S
G
A
L
D
L
L
D
A
E
R
S
S
Y
S
A
E
G
A
A
L
S
A
Q
L
T
R
A
E
N
L
A
D
L
Y
K
A
---------------
L
G
G
-----------------------
G
L
K
R
D
T
Q
T
----------------------------------------------------------------------------------------------------------
36
Fugue
61.60
11%
14
- C3 -
4D8O
-
ANK2_HUMAN
A:
[964-1529]
EFSGFL
V
S
F
M
V
D
AR
G
G
A
M
R
G
CRHNG
L
R
I
I
I
P
P
R
K
C
T
--
A
P
T
R
V
T
C
R
L
V
K
R
H
R
L
A
T
M
PP
M
V
-----------
E
G
E
G
L
-----
A
S
R
L
I
E
V
G
P
S
G
A
Q
F
L
G
P
V
I
V
E
I
P
H
F
A
A
L
R
G
K
E
R
E
L
V
V
L
R
S
E
NGD
S
W
K
E
H
F
C
D
Y
G
M
D
E
V
L
D
S
P
E
D
L
E
K
K
R
I
C
R
I
I
T
R
D
F
-------
P
Q
Y
F
A
V
V
S
R
I
K
Q
D
S
N
L
I
G
P
E
G
G
V
L
S
S
T
V
V
P
Q
-----
V
Q
A
V
F
P
E
G
A
L
T
K
R
I
R
V
G
L
Q
A
Q
P
M
H
S
E
L
V
K
K
I
L
G
N
K
A
T
-
F
S
P
I
V
T
L
E
P
R
R
R
K
F
H
K
P
----------
I
T
M
T
I
P
V
P
K
A
S
----
G
D
A
P
-----
T
L
R
L
L
C
S
I
T
G
G
T
T
P
A
Q
W
E
D
I
T
G
T
T
P
--
L
T
F
V
---------
N
E
C
V
S
F
T
T
N
V
S
A
R
F
W
L
---
I
D
C
R
Q
I
Q
E
S
V
T
F
A
S
Q
V
Y
R
E
I
I
-
C
V
P
Y
M
A
K
F
V
---
V
F
--
A
K
S
-
H
D
P
-------
I
---
E
A
R
L
R
C
F
C
M
T
D
D
K
V
D
K
T
L
E
Q
Q
E
N
----------
F
A
E
V
A
R
S
R
D
----------
V
E
V
L
E
G
K
P
I
-------
Y
----
V
D
C
-----
F
G
N
-
L
V
-
P
L
T
Q
H
H
I
F
S
F
F
A
F
K
E
N
R
L
P
L
F
V
K
V
R
---
D
T
T
Q
E
P
C
G
R
L
S
F
M
----
K
E
P
H
Q
------
A
I
C
N
L
N
I
T
L
P
--
I
Y
T
E
E
R
L
A
Y
I
A
D
------------
H
L
G
F
S
W
T
E
L
A
R
-
E
L
D
F
T
----------
E
E
Q
I
H
Q
I
R
I
E
N
P
N
S
L
Q
D
Q
S
H
A
L
L
K
Y
W
L
E
R
D
G
K
H
A
T
-------------------------------
D
T
N
L
V
E
C
L
T
K
I
N
R
M
D
I
V
H
-----------------------------------------------------------------------------------------------------------
32
Fugue
59.90
8%
19
- C4 -
1SHY
-
MET_HUMAN
B:
[40-564]
------------------------------KY
Q
L
P
N
--
F
T
A
E
T
P
I
Q
N
V
I
L
H
E
H
H
I
F
--
L
G
-----------
A
----------
T
N
Y
I
Y
V
L
N
E
E
D
L
Q
K
V
A
E
Y
K
T
G
P
V
L
E
H
P
D
C
F
P
C
Q
D
C
S
S
K
A
N
---------
L
S
G
G
V
W
K
D
N
I
N
M
A
L
V
V
D
T
Y
Y
D
D
Q
L
I
S
C
G
SVNRG
T
C
Q
R
H
V
F
P
H
N
H
T
A
D
I
Q
S
E
V
H
C
I
F
S
P
Q
I
E
E
P
S
Q
C
PDCVV
S
A
L
G
A
K
V
L
S
S
V
K
D
R
F
I
N
F
F
V
G
N
T
I
N
S
S
Y
F
P
D
H
P
L
H
S
I
-
S
V
R
R
L
K
E
T
K
D
G
F
M
F
L
T
D
Q
SYIDVLPEF
R
D
S
Y
P
I
K
Y
V
H
A
----
F
E
S
N
N
F
I
Y
F
L
T
V
Q
R
E
T
L
D
A
Q
T
F
H
T
R
I
I
R
F
C
S
I
N
S
GL
H
S
Y
M
E
M
P
L
E
C
I
L
T
K
E
V
F
N
I
L
Q
A
A
Y
V
S
K
P
G
---
A
Q
L
A
R
Q
I
G
A
S
L
N
D
D
I
L
F
G
V
F
A
Q
S
K
P
D
S
A
E
P
M
---
D
R
--
S
A
M
-
C
A
F
P
-
I
K
Y
V
N
D
---
F
F
N
K
I
N
V
R
C
--------
L
Q
H
F
Y
G
--------
P
N
H
E
H
C
F
N
R
D
E
Y
---
R
T
E
-
F
T
T
A
L
Q
R
V
D
L
F
-------
M
-----------------
G
-
Q
F
S
E
V
L
L
T
S
I
S
T
F
I
K
G
D
--
L
T
I
A
N
L
---
G
T
S
E
G
-----------------------
R
F
M
Q
V
V
V
S
R
S
--
G
P
S
T
P
H
V
N
F
L
L
D
------------
S
H
P
V
S
P
E
V
I
V
E
-
H
T
L
N
Q
N
G
Y
T
L
V
I
T
G
K
K
I
T
K
I
P
L
N
G
L
G
C
R
H
F
Q
S
C
S
Q
C
L
S
A
P
P
F
V
Q
C
G
W
C
H
D
K
---------------
C
V
R
S
E
-------
E
C
L
S
G
T
W
T
Q
Q
I
C
L
P
A
-----------------------------------------------------------------------------------------------------------------
35
Fugue
55.90
12%
21
* C4 *
1JFX
8
LYSM1_STRGL
A:
[1-217]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
S
G
V
Q
G
I
D
V
S
H
W
Q
G
S
I
N
W
S
S
V
K
S
A
G
--
M
S
F
A
Y
I
K
A
T
E
G
T
N
Y
K
D
D
R
---------
F
S
A
N
Y
T
N
A
Y
N
A
----
G
I
I
R
G
A
Y
H
F
-
A
R
P
N
A
S
S
G
T
A
Q
A
D
Y
F
A
S
N
G
G
G
W
S
R
--
D
N
R
T
L
P
G
V
L
D
I
E
H
N
P
S
G
A
M
C
Y
G
L
S
T
T
Q
M
R
---
T
W
I
N
D
F
H
A
R
Y
K
A
R
T
T
R
D
V
V
I
Y
T
T
A
S
W
W
N
T
C
T
GSW
N
G
--
M
A
A
-
K
S
P
F
-
W
V
A
H
W
G
---
V
S
A
P
T
V
P
S
G
F
P
T
W
T
F
W
Q
Y
S
A
T
G
R
--------
V
G
G
V
S
G
D
V
D
R
N
K
F
NG
S
A
A
-
R
L
L
A
L
A
N
N
T
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
55.35
19%
8
- C4 -
4QRK
2
?
A:
[9-220]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
K
E
E
I
K
I
V
E
P
N
G
A
E
K
T
K
L
N
L
N
F
G
V
G
K
L
N
I
---
S
G
NE
E
K
L
M
K
G
K
F
-
I
Y
S
E
N
E
WK
P
E
I
K
Y
E
V
K
D
K
D
G
E
L
E
I
S
Q
P
G
L
K
S
G
NVSLNN
K
R
N
E
W
N
I
N
L
N
E
K
I
P
---
T
E
I
-
K
L
S
-
L
G
T
G
E
F
K
-------
A
DLS
K
I
N
L
-----
K
E
L
N
V
G
M
G
V
G
K
V
D
L
D
---
I
S
G
N
Y
K
N
N
V
K
V
N
I
E
---
G
G
V
G
----
E
A
T
V
Y
----
L
P
-
K
S
------
I
G
V
K
I
K
A
E
K
G
V
G
A
V
N
A
N
G
F
I
V
E
G
E
------------
N
I
Y
K
N
S
Q
Y
G
K
S
-
K
N
S
I
E
V
N
I
E
A
G
V
G
A
I
N
I
K
Q
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
54.95
26%
25
- C5 -
3TGK
2
TRY2_RAT
E:
[10-103]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
G
Y
T
CQENSVP
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
FVNAAK
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
V
N
E
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
S
Y
P
G
K
---------------
I
T
D
N
M
-------
V
C
V
G
F
L
E
G
G
K
D
S
C
Q
G
N
S
G
G
P
V
V
----------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
53.78
26%
30
- C5 -
1F5R
1
TRY2_RAT
A:
[9-103]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
G
G
Y
T
CQENSVP
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
F
V
N
A
A
K
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
E
P
D
L
L
K
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
S
Y
P
G
K
I
T
---------------
D
N
M
V
C
-------
V
G
F
L
E
G
G
K
D
S
C
Q
G
D
S
G
G
P
V
V
C
N
----------------------------------------------------------------------------------------------------------
31
Fugue
52.33
14%
20
* C6 *
4NFC
-
PILRB_HUMAN
A:
[1-120]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-
L
Y
G
V
T
Q
---
P
K
H
L
S
A
S
M
G
G
S
V
E
I
P
F
S
F
Y
Y
P
W
E
L
A
IVPN
V
R
I
S
W
R
R
G
H
F
H
G
Q
S
---
F
Y
S
-
T
R
P
P
S
I
H
K
D
Y
V
-------
N
---
R
L
F
L
-----
N
W
T
E
G
Q
-
E
S
G
F
L
R
I
S
N
L
R
K
E
D
Q
S
V
Y
F
C
R
V
E
L
D
---
T
R
R
S
G
R
Q
Q
L
Q
S
I
K
----
G
T
-
K
L
------
T
I
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
51.76
26%
33
- C5 -
1EZU
1
TRY2_RAT
C:
[14-95]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
D
-
E
Q
FVNAAK
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
N
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
T
L
S
S
G
V
N
E
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
---------------
S
Y
P
G
K
-------
I
T
D
N
M
V
C
V
G
F
L
E
G
G
K
D
S
C
Q
G
D
S
----------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
51.53
26%
36
* C5 *
1K9O
-
TRY2_RAT
E:
[29-113]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
FVNAAK
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
T
L
S
S
G
V
N
E
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
---------------
S
Y
P
G
K
-------
I
T
D
N
M
V
C
V
G
F
L
E
G
G
K
D
S
C
Q
G
D
A
----------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
51.06
26%
25
- C5 -
1AMH
1
TRY2_RAT
A:
[14-95]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
F
V
N
A
A
K
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
T
L
S
S
G
V
N
E
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
---------------
S
Y
P
G
K
-------
I
T
D
N
M
V
C
V
G
F
L
E
G
G
K
S
S
C
Q
G
D
S
----------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
50.81
26%
33
- C5 -
3TGJ
1
TRY2_RAT
E:
[24-105]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
FVNAAK
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
S
Y
P
G
K
I
T
D
N
---------------
M
V
C
V
G
-------
F
L
E
G
G
K
D
S
C
Q
G
D
A
G
G
P
V
V
C
N
G
E
----------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
50.68
26%
33
- C5 -
1BRB
-
TRY2_RAT
E:
[29-113]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
FVNAAK
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
T
L
S
S
G
V
N
E
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
---------------
S
Y
P
G
K
-------
I
T
D
N
M
V
C
V
G
L
E
G
G
G
S
C
Q
G
D
S
G
G
----------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
50.65
26%
33
- C5 -
1CO7
1
TRY2_RAT
E:
[36-117]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
FVNAAK
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
H
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
T
L
S
S
G
V
N
E
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
---------------
S
Y
P
G
K
-------
I
T
D
N
M
V
C
V
G
F
L
E
G
G
K
D
S
C
Q
G
D
S
----------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
50.40
26%
30
- C5 -
3TGI
1
BPT1_BOVIN (first)
E:
[14-95]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
FVNAAK
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
T
L
S
S
G
V
N
E
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
---------------
S
Y
P
G
K
-------
I
T
D
N
M
V
C
V
G
F
L
E
G
G
K
D
S
C
Q
G
D
S
----------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
50.32
26%
27
- C5 -
1FY8
2
TRY2_RAT
E:
[9-103]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
G
G
Y
T
CQENSVP
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
FVNAAK
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
S
Y
P
G
K
I
T
D
---------------
N
M
V
C
V
-------
G
F
L
E
G
G
K
D
S
C
Q
G
D
S
G
G
P
V
V
C
N
G
----------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
50.20
26%
27
- C5 -
1ANB
1
TRY2_RAT
A:
[14-95]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
F
V
N
A
A
K
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
T
L
S
S
G
V
N
E
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
---------------
S
Y
P
G
K
-------
I
T
D
N
M
V
C
V
G
F
L
E
G
G
K
D
S
C
Q
G
D
S
----------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
50.18
26%
28
- C5 -
1BRC
-
TRY2_RAT
E:
[29-113]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
---
Q
V
S
L
-----
N
S
G
Y
H
F
-
C
G
G
S
L
I
N
D
Q
W
V
V
S
A
A
H
C
Y
K
S
R
I
Q
V
------
R
L
G
E
H
N
I
N
V
L
E
----
G
N
-
E
Q
FVNAAK
I
I
K
H
P
N
F
D
R
K
--
T
L
N
N
D
I
M
L
I
---------------
K
L
S
S
P
V
K
L
N
A
R
-
V
A
T
V
A
L
P
S
S
C
A
P
A
G
T
Q
C
L
I
S
G
W
G
N
T
L
S
S
G
V
N
E
P
D
L
L
Q
C
L
D
A
P
L
L
P
Q
A
D
C
E
A
---------------
S
Y
P
G
K
-------
I
T
D
N
M
V
C
V
G
L
E
G
G
G
S
C
Q
G
D
S
G
G
----------------------------------------------------------------------------------------------------------