@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0445: (2015-12-01 )
MVLFTGATVEEAIEKGLQELNISRLRAHIKVVSREKKGFLGFGKKPAKVEIEGITDEVTDINESVALKNIKNVPSSVDVVEEYIEEVDETLEKEDVSQPELPKIDDKNVVTTSEAIEKIDLLPNIEVAAAQVTKYVENIIYEMDLDATIETTTSKRQISLQIETPEAGRIIGYHGKVLKSLQLLAQNYLHDRFSKSFSVSINVHDYVEHRTETLIDFSKKIARRVLETNEPYHMDPMSNSERKTVHKTIATIEGVESYSEGNDPNRFVVVTKK
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........-10....--....---------------20........30..-------......40..--.....------.50.....---------------..-------.60.--....-----...70...----------------------------.....80--........-------90...-----------------...-..100.......110..-....---.120------.----...----------....130---....---------------..---.140.....-..150.-...--...160.......---------170----..-.....180..-.....190----------------......-----..200---------........210-------------------........----220..--.....230......-.240-........250---------..-----.....260.-......-270.--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
L
FTG
A
T
V
-
E
E
A
I
E
K
--
G
L
Q
E---------------L
N
I
S
R
L
R
A
H
I
K
V
V
S-------REKKGFLGFG--KKP
A
K
------
V
E
I
EGITD---------------
E
V
-------TDI
N
--
E
S
V
A
-----
L
K
N
I
KNVP----------------------------S
S
V
D
V
V
E
--
E
Y
I
E
E
V
D
E
-------
T
L
E
KE-----------------DVS-QPELPKIDDKNVV
T
T
S
E
-
A
I
E
K
---
I
DL-------L----PN
I
----------
E
V
A
A
A
Q
V
---
T
K
Y
V
---------------
E
N
---
I
I
Y
EMDLD
A
-
T
I
ETTT-S
K
R
--
Q
I
S
L
Q
I
ETPEA
G
R
---------
I
I
G----
Y
H
-
G
K
V
L
K
S
L
Q
L
L
-
A
Q
N
Y
L
H
D
-----------------
R
FSK
S
F
-----
S
V
S
I
----------
N
V
H
D
Y
V
E
H
R
T
--------------------
E
T
L
I
D
F
S
K
----
K
I
A
R
R
--
V
L
ETNEPYHMDPMS-NS
E
--
R
K
T
V
H
K
T
I
A
T
I
---------
E
G
-----
V
E
S
YSEGND-P
N
R
F
V
V
-
V
TKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
59.05
11%
-90
- C8 -
2PT7
-
?
G:
[115-259]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
H
E
I
---
K
Q
E
L
---------------
K
D
---
L
F
S
H
L
P
Y
K
I
N
K
V
E
V
S
L
Y
E
P
G
--
V
L
L
I
D
I
D
G
E
D
S
A
L
---------
L
I
G
----
E
K
-
G
Y
R
Y
K
A
L
S
Y
L
-
L
F
N
W
I
H
P
-----------------
T
Y
--
G
Y
-----
S
I
R
L
----------
E
I
S
T
F
L
Q
N
Q
E
--------------------
K
V
M
D
T
Q
L
Q
----
S
V
I
M
T
--
V
H
E
V
G
K
G
Q
M
K
-----
A
P
D
--
G
V
L
T
Y
I
A
L
K
K
L
---------
R
K
AFPNK
Y
V
S
I
K
T
N
L
N
-
D
E
K
Y
I
V
-
I
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
58.48
17%
-15
- C3 -
4NUZ
1
?
A:
[1-892]
MKIPEKIPMKPLHGP
L
Y
G
G
Y
F
R
TWHDKTSDPTEKDKVNSMGELPKEVD
L
A
F
I
F
H
D
WTKDY
S
L
F
W
K
E
L
A
T
K
H
V
P
K
L
N
K
Q
G
T
R
V
I
R
T
I
P
W
R
F
L
A
GGDNSGIAEDTSKYPNT
P
E
G
N
K
A
L
A
K
A
I
V
D
E
YVYKYNLD
G
L
D
V
Q
VEHDS
I
P
K
V
DKKED
T
A
G
V
E
R
S
I
Q
V
F
E
E
I
G
K
L
IGPKGVDKS
R
L
F
I
M
D
S
TYMADKNPLIERGAPYIN
L
L
L
V
Q
VYGSQGEKGGWEPVSNRPEKT
M
E
E
R
W
Q
G
Y
SKYIRPEQ
Y
M
I
G
F
S
F
YEENAQEGNLWYDINSRKDEDKANGINTDITGT
R
A
E
R
Y
A
R
WQPKTGGVKG
G
I
F
S
Y
AIDRDGVAHQPKKYAKKDATDNIFHSDY
S
V
S
K
A
L
K
T
V
M
L
K
DKSYDLID
E
K
D
F
P
D
K
A
L
-
R
E
A
V
M
A
Q
V
G
T
R
K
---------------
G
D
L
E
R
F
N
G
T
L
R
L
D
N
-------
P
A
I
Q
S
L
E
G
L
N
KF
K
K
L
A
Q
------
L
D
L
I
G
L
S
R
----------------
I
-------
T
K
L
D
--
R
S
V
L
-----
P
A
N
M
K
-------------------------------
P
G
K
D
T
L
E
--
T
V
L
E
T
Y
K
K
-------
D
N
K
E
E
-----------------
P
A
T
-
I
P
P
V
-----
S
L
K
V
S
G
L
T
-
G
L
K
E
---
L
D
L
SGFDRET
L
----
A
G
L
----------
D
A
A
T
L
T
S
---
L
E
K
V
DISGNKLDLAPGT
E
N
R
Q
---
I
F
D
T
M
L
S
T
I
-
S
N
H
V
G
S
-
N
E
Q
--
T
V
K
F
D
K
Q
K
P
T
G
H
Y
---------
P
D
T
----
Y
G
-
K
T
S
L
R
L
P
V
A
N
-
E
K
V
D
L
Q
S
-----------------
Q
L
L
--
F
-----
G
T
V
T
----------
N
Q
G
T
L
I
N
S
E
A
--------------------
D
Y
K
A
Y
Q
N
H
----
K
I
A
G
R
--
S
F
V
D
S
N
Y
H
Y
N
N
F
K
V
-
S
Y
E
--
N
Y
T
V
K
V
T
D
S
T
L
---------
G
T
-----
T
T
D
K
T
L
A
T
D
-
K
E
E
T
Y
K
-
V
D
F
F
S
PADKTKAV
H
T
A
K
V
I
V
G
DEKTMMVNLAEG
A
T
V
I
G
GSAD
P
V
N
A
R
K
V
F
DGQLGSETDNISLGWDS
K
Q
S
I
I
F
K
L
KEDGLIK
H
W
R
F
F
N
DSARNPETTNKPIQ
E
A
S
L
Q
I
F
NIKDYN
L
D
N
L
L
E
NPNKFDDEKYWITV
D
T
Y
S
A
QGERAT
A
F
S
N
T
L
N
NITSK
Y
W
R
V
V
F
D
TKGDRYSSPVVP
E
L
Q
I
L
G
Y
PLPN
A
D
T
I
M
K
T
V
T
T
A
K
E
L
S
Q
QKDKFS
Q
K
M
L
D
E
L
K
I
K
E
M
A
L
E
T
S
L
N
SKIFD
V
T
A
I
N
A
N
A
G
V
L
K
D
C
I
EK-------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
55.05
21%
6
- C1 -
5CZZ
7
?
A:
[6-1055]
-R
N
Y
I
L
G
L
DIGIT
S
V
G
Y
G
I
I
D
YETRDVI
D
A
G
V
R
L
F
K
EAN
V
E
N
N
E
G
R
R
S
K
R
G
A
R
R
L
K
R
R
R
R
H
R
I
Q
R
V
K
K
L
L
F
D
Y
NLLTDHSELSGIN
P
Y
E
A
R
V
K
G
L
S
Q
K
L
S
E
E
E
F
S
A
A
L
L
H
L
A
K
R
R
G
V
H
NVNE
V
E
E
D
TGNELS
T
K
E
Q
I
S
R
N
S
K
A
L
EEKY
V
A
E
L
Q
L
E
R
L
K
K
DGEVRGSINRFK
T
S
D
Y
V
K
E
A
K
Q
L
L
K
V
Q
KAYHQLD
Q
S
F
I
D
T
Y
I
D
L
L
E
T
R
R
T
YYEGPGEGSPFGWKD
I
K
E
W
Y
E
M
L
M
G
H
C
TYFPEELRSVKYA
Y
N
A
D
L
Y
N
A
L
N
D
L
N
N
L
V
I
T
R
DENEKLE
Y
Y
E
K
F
Q
I
I
E
N
VFKQKKKPT
L
K
Q
I
A
K
E
I
LVNEEDIKG
Y
R
V
T
STG
K
P
E
F
T
N
L
K
V
Y
H
D
I
K
D
I
TARKEIIEN
A
E
L
L
D
Q
I
A
K
I
L
T
I
Y
Q
S
----
S
E
D
I
Q
E
--
E
L
T
N
---------------
L
N
S
E
L
T
Q
E
E
I
E
Q
I
S
-------
N
-
L
K
G
Y
T
G
-
T
--
H
N
L
S
L
------
K
A
I
N
L
I
L
D
---------------
E
L
-------
W
H
T
N
DN
Q
I
A
I
-----
F
N
R
L
K
L
V
P
----------------------------
K
K
V
D
L
S
Q
--
Q
--
K
E
I
P
T
-------
T
L
V
D
D
-----------------
F
I
L
-
S
P
V
V
K
R
S
F
I
Q
S
I
K
V
I
N
A
-
I
I
K
K
---
Y
G
L
-------
P
----
N
D
I
I
I
E
L
A
REKN
S
K
D
A
Q
K
M
I
---
N
E
M
Q
---------------
K
R
---
N
R
Q
T
N
E
R
I
E
-
E
I
I
R
T
T
-
G
K
E
--
N
A
K
Y
L
I
E
K
I
K
L
H
D
---------
M
Q
E
-------
G
K
C
L
Y
S
L
E
A
I
P
L
E
D
L
L
N
N
-----------------
P
F
N
Y
E
V
-----
D
H
I
I
----------
P
R
S
V
S
F
D
N
S
F
--------------------
N
N
K
V
L
V
K
Q
----
E
E
A
S
K
--
K
-
G
N
R
T
P
F
Q
Y
L
S
S
S
-
D
S
K
IS
Y
E
T
F
K
K
H
I
L
N
L
A
K
GKGRIS
K
T
K
-----
K
E
Y
L
L
E
E
R
D
-
I
N
R
F
S
V
-
Q
K
D
F
I
N
R
NLVDTR
Y
A
T
R
G
L
M
N
L
L
R
S
Y
F
R
V
N
NLD
V
K
V
K
S
I
N
G
G
F
T
S
F
L
R
R
K
W
KFKKERNKGYK
H
H
A
E
D
A
L
I
I
A
N
A
D
F
I
F
K
E
WKKL
D
K
A
K
K
V
M
E
NQMFMPEIET
E
Q
E
Y
K
E
I
FITPHQI
K
H
I
K
D
FK
D
Y
K
Y
S
H
R
V
D
KKPNRELIND
T
L
Y
S
T
R
K
D
DKG
N
T
L
I
V
N
N
L
N
GLYDKDND
K
L
K
K
L
I
N
K
SPEKL
L
M
Y
H
H
D
P
Q
T
Y
Q
K
L
K
L
I
M
E
Q
Y
G
DEKN
P
L
Y
K
Y
Y
E
E
TGNYLTKYSKKDN
G
P
V
I
K
K
I
K
Y
Y
G
N
KL
N
A
H
L
D
ITDDYPNSR
N
K
V
V
K
L
SLKPY
R
F
D
V
Y
L
D
NG
V
Y
K
F
V
T
V
K
NLD
V
I
K
K
EN
Y
Y
E
V
N
S
K
A
Y
E
E
A
K
K
L
K
KISNQ
A
E
F
I
A
SFYNND
L
I
K
I
NG
E
L
Y
R
V
IGVNNDLLN
R
I
E
V
N
M
I
DIT
Y
R
E
Y
L
E
N
M
NDKRPP
R
I
I
K
T
IASKTQ
S
I
K
K
Y
S
T
D
ILG
N
L
Y
E
V
K
S
K
K
HPQIIKK
30
HHSearch
55.00
16%
-75
* C8 *
2YKR
-
RS3_ECOLI
C:
[36-125]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
V
---
R
Q
Y
L
---------------
T
K
---
E
L
A
K
A
S
V
-
S
-
R
I
V
I
E
R
-
P
A
K
--
S
I
R
V
T
I
H
T
A
R
P
G
I
---------
V
I
G
----
K
K
-
G
E
D
V
E
K
L
R
K
V
-
V
A
D
I
A
G
V
----------------------------
P
A
Q
I
----------
N
I
A
E
V
-
R
K
P
E
--------------------
L
D
A
K
L
V
A
D
----
S
I
T
S
Q
--
L
E
R
R
V
M
F
R
R
A
M
K
R
A
-
V
Q
N
--
A
M
R
L
G
A
K
G
I
K
V
---------
E
V
-----
S
G
R
L
G
G
A
E
I
-
A
R
T
E
W
Y
-
R
E
G
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
54.19
12%
-133
- C8 -
1WH9
-
RS3_HUMAN
A:
[11-69]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
---
N
E
F
L
---------------
T
R
---
E
L
A
E
D
G
Y
-
S
-
G
V
E
V
R
V
-
T
P
T
--
R
T
E
I
I
I
L
A
T
R
T
Q
N
---------
V
L
G
----
E
K
-
G
R
R
I
R
E
L
T
A
V
-
V
Q
K
R
F
G
F
-----------------
P
E
G
S
V
E
-----
L
Y
A
E
----------
K
V
A
T
R
G
S
G
P
S
--------------------
S
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
54.05
11%
-54
- C8 -
2PT7
-
?
G:
[115-259]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
H
E
I
---
K
Q
E
L
---------------
K
D
---
L
F
S
H
L
P
Y
K
I
-
N
K
V
E
V
S
-
L
Y
E
PG
V
L
L
I
D
I
D
G
E
D
S
A
L
---------
L
I
G
----
E
K
-
G
Y
R
Y
K
A
L
S
Y
L
-
L
F
N
W
I
H
P
-----------------
T
Y
G
Y
-------
S
I
R
L
----------
E
I
S
T
F
L
Q
N
Q
E
--------------------
K
V
M
D
T
Q
L
Q
----
S
V
I
M
T
--
V
H
E
V
G
K
G
Q
M
K
A
P
D
G
-
V
L
T
--
Y
I
A
L
K
K
L
R
K
A
F
P--------
N
K
-----
Y
V
S
I
K
T
N
L
N
-
D
E
K
Y
I
V
-
I
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
53.73
20%
-11
- C7 -
4FDW
19
?
A:
[21-401]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASLEDFSIEQLPAKTIYALGE
N
I
D
L
T
G
L
N
V
-
T
G
K
Y
D
D
--
G
K
Q
R
P
V
K
V
T
SEQISGFSSS
V
P
V
D
K
Q
E
V
T
I
T
I
E
G
-------
K
Q
K
S
F
S
V
H
I
S
----
P
V
R
------
V
E
N
G
V
L
T
E
---------------
I
L
-------
K
G
Y
N
--
E
I
I
L
-----
P
N
S
V
K
S
I
P
KDAFRNSQIA
K
V
V
L
N
EGLK
S
I
G
D
MAFFN
S
T
V
Q
E
I
V
F
P
S
T
L
E
Q
L
K
E
DIFYYCY
N
L
K
K
A
-----------------
D
L
S
-
K
T
K
I
T
K
L
P
A
S
T
F
V
Y
A
G
---
I
E
E
---
V
L
L
-------
P
----
V
T
L
----------
K
E
I
G
S
Q
A
FLK
T
S
Q
L
---------------
K
T
---
I
E
I
P
E
N
V
S
T
-
I
G
Q
E
A
F
-
R
E
S
--
G
I
T
-
T
V
K
L
P
N
G
V
T
---------
N
I
A
SRAF
Y
Y
-
C
P
E
L
A
E
V
T
T
Y
-
G
S
T
F
N
D
D
PEAMIHPYCLEGCPKLA
R
F
E
I
P
E
-----
S
I
R
I
L
G
Q
GLLGGNR
K
V
T
Q
L
T
I
P
A
N
--------------------
V
T
Q
I
N
F
S
A
FNNT
G
I
K
E
V
--
K
V
E
G
T
T
P
P
Q
V
F
E
K
V
W
Y
G
F
--
P
D
D
I
T
V
I
R
V
P
A
---------
E
S
-----
V
E
K
Y
K
N
A
N
G
-
W
R
D
F
T
N
K
I
T
T
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
51.46
13%
-83
- C8 -
2VQE
-
RS3_THET8
C:
[38-126]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
---
R
G
L
L
---------------
E
K
---
E
L
Y
S
A
G
L
-
A
-
R
V
D
I
E
R
-
A
A
D
--
N
V
A
V
T
V
H
V
A
K
P
G
V
---------
V
I
G
----
R
G
-
G
E
R
I
R
V
L
R
E
E
-
L
A
K
L
T
G
K
---------------------
N
V
-------
A
L
----------
N
V
Q
E
V
-
Q
N
P
N
--------------------
L
S
A
P
L
V
A
Q
----
R
V
A
E
Q
--
I
E
R
R
F
A
V
R
R
A
I
K
Q
A
-
V
Q
R
--
V
M
E
S
G
A
K
G
A
K
V
---------
I
V
-----
S
G
R
I
G
G
A
E
Q
-
A
R
T
E
W
A
-
A
Q
G
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
46.61
17%
3
- C6 -
4J3R
9
?
A:
[4-383]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
L
P
T
T
A
S
S
S
T
A
V
A
S
S
--
Q
L
D
Q
---------------
L
A
N
F
A
Y
N
V
T
T
D
S
V
A
GCTLQN
L
R
V
R
R
D
W
R
A
F
S
--
K
T
Q
K
K
------
D
Y
I
N
S
V
L
C
L
Q
K
LPSRTPAHLAPG
A
R
-------
T
R
Y
D
--
D
F
V
A
T
H
I
N
Q
T
Q
I
I
H
Y
T
G
----------------------------
T
F
L
A
W
H
R
--
Y
F
I
Y
E
F
E
Q
-------
A
L
R
D
E
CSYTG
D
Y
P
Y
W
NWGADAD
N
M
E
-
K
S
Q
V
F
D
G
S
E
T
S
M
S
G
N
G
E
-
Y
I
P
N
Q
G
D
I
K
L
-------
L
L
GNY
P
A
I
----------
D
L
P
P
G
S
G
---
G
G
C
V
---------------
T
S
GPF
K
D
Y
K
L
N
L
G
P
-
A
A
L
S
L
P
-
G
G
N
--
M
T
A
A
A
N
P
L
T
Y
N
P
R
C
M
K
R
S
L
T
T
E
I
L
Q
----
R
Y
-
N
T
F
P
K
I
V
E
L
I
-
L
D
S
D
D
I
W
-----------------
D
F
Q
M
T
M
Q
GVPG
S
G
S
I
----------
G
V
H
G
G
G
H
Y
S
M
GGDPGRDVYVSPGDTA
F
W
L
H
H
G
M
I
D
R
V
W
----
W
I
W
Q
N
L
D
L
R
K
R
Q
N
A
I
S
G
T
G
T
F
-
M
N
N
--
P
A
S
P
N
T
T
L
D
T
V
---------
I
D
-----
L
G
Y
A
N
G
G
P
I
-
A
M
R
D
L
M
-
S
T
T
A
GP
F
C
Y
V
Y
L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
44.71
14%
16
- C4 -
4OBX
2
COQ5_YEAST
A:
[23-257]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
A
N
R
Y
D
L
M
-
N
D
V
M
S
L
--
G
I
H
R
---------------
L
W
K
D
H
F
I
N
K
L
------------------
D
A
G
--
K
R
P
N
S
T
T
P
L
N
F
I
D
V
A
G
G
S
G
---------------
D
I
-------
A
F
G
L
--
L
D
H
A
-----
E
S
K
F
G
D
T
E
----------------------------
S
T
M
D
I
V
D
--
I
N
P
D
M
L
K
E
-------
G
E
K
R
A
-----------------
M
E
Q
-
G
K
Y
F
K
D
P
R
V
R
F
L
V
S
N
G
E
-
K
L
E
E
---
I
D
-------------------------------
S
D
---
S
K
D
I
---------------
Y
T
---
V
S
F
G
I
R
N
F
T
-
D
I
Q
K
G
L
-
N
T
A
--
Y
R
V
L
K
P
G
----
G
I
---------
F
Y
C
----
L
E
F
S
K
I
E
N
P
L
M
D
F
-
A
Y
Q
Q
W
A
K
-----------------
V
L
P
V
M
G
-----
S
M
I
A
----------
N
D
Y
D
S
Y
Q
Y
L
V
--------------------
E
S
I
E
R
F
------------------------
P
D
Q
-
E
T
F
--
K
S
M
I
E
K
--
A
G
F
---------
K
S
-----
A
G
Y
E
S
L
T
F
G
-
I
C
A
I
H
W
-
G
I
K
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
43.07
29%
-15
- C8 -
1OGD
-
RBSD_BACSU
A:
[33-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
D
-------
G
V
L
K
I
-----------------
D
L
S
L
K
P
G
L
P
A
F
Q
D
T
A
A
V
L
A
E
E
M
A
V
E
K
---
V
I
A
-------
A
----
A
E
I
----------
K
A
S
N
Q
E
N
---
A
K
F
L
---------------
E
N
---
L
F
S
E
Q
E
I
E
Y
-
L
S
H
E
E
F
-
K
L
L
--
T
K
D
A
K
A
V
I
R
T
G
E
F
---------
T
P
Y
----
A
N
-
C
I
L
Q
A
G
V
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
42.42
29%
-14
- C8 -
1OGE
-
RBSD_BACSU
A:
[33-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
D
-------
G
V
L
K
I
-----------------
D
L
S
L
K
P
G
L
P
A
F
Q
D
T
A
A
V
L
A
E
E
M
A
V
E
K
---
V
I
A
-------
A
----
A
E
I
----------
K
A
S
N
Q
E
N
---
A
K
F
L
---------------
E
N
---
L
F
S
E
Q
E
I
E
Y
-
L
S
H
E
E
F
-
K
L
L
--
T
K
D
A
K
A
V
I
R
T
G
E
F
---------
T
P
Y
----
A
N
-
C
I
L
Q
A
G
V
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
41.87
29%
-7
- C8 -
1OGC
-
RBSD_BACSU
A:
[33-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
D
-------
G
V
L
K
I
-----------------
D
L
S
L
K
P
G
L
P
A
F
Q
D
T
A
A
V
L
A
E
E
M
A
V
E
K
---
V
I
A
-------
A
----
A
E
I
----------
K
A
S
N
Q
E
N
---
A
K
F
L
---------------
E
N
---
L
F
S
E
Q
E
I
E
Y
-
L
S
H
E
E
F
-
K
L
L
--
T
K
D
A
K
A
V
I
R
T
G
E
F
---------
T
P
Y
----
A
N
-
C
I
L
Q
A
G
V
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
41.54
24%
-1
- C8 -
2CPM
-
SPAG7_HUMAN
A:
[46-108]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
F
R
K
R
M
E
--------------------
K
E
V
S
D
F
I
Q
----
D
S
--------
G
Q
I
K
K
K
F
Q
P
M
N
-
K
I
E
--
R
S
I
L
H
D
V
V
E
V
----------
A
G
-----
L
T
S
F
S
F
G
E
D
D
D
C
R
Y
V
M
-
I
F
K
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
40.59
21%
4
- C8 -
3HJV
8
?
A:
[169-303]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
Q
------
V
V
I
A
G
Q
K
D
---------------
A
V
E
R
A
G
V
L
C
K
E
A
G
--
A
K
R
A
-----
L
P
L
P
V
S
V
P
----------------------------
S
H
C
A
L
M
K
--
P
A
A
D
E
L
A
K
-------
T
L
A
E
L
-----------------
E
F
N
-
A
P
Q
I
P
V
I
N
N
V
D
V
V
A
E
T
D
-
P
V
K
I
---
K
D
A
-------
L
----
I
R
Q
----------
L
Y
S
P
V
R
W
---
T
E
C
V
---------------
E
Q
------------------
M
-
S
A
Q
--
G
V
E
K
L
I
E
M
G
P
G
K
V
---------
L
T
G
----
L
T
-
K
R
I
V
K
T
L
E
G
V
-
A
V
N
D
V
A
S
-----------------
L
D
A
V
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
40.53
29%
-19
- C8 -
1OGF
-
RBSD_BACSU
A:
[33-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
D
-------
G
V
L
K
I
-----------------
D
L
S
L
K
P
G
L
P
A
F
Q
D
T
A
A
V
L
A
E
E
M
A
V
E
K
---
V
I
A
-------
A
----
A
E
I
----------
K
A
S
N
Q
E
N
---
A
K
F
L
---------------
E
N
---
L
F
S
E
Q
E
I
E
Y
-
L
S
H
E
E
F
-
K
L
L
--
T
K
D
A
K
A
V
I
R
T
G
E
F
---------
T
P
Y
----
A
N
-
C
I
L
Q
A
G
V
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
39.81
18%
-39
- C8 -
1WF3
-
ERA_THET8
A:
[240-279]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
K
A
I
---------
V
I
G
----
E
G
-
G
R
K
I
K
E
I
G
Q
A
-
T
R
K
Q
L
E
A
-----------------
L
L
G
K
K
V
-----
Y
L
D
L
----------
E
V
K
V
Y
P
D
W
R
K
--------------------
D
P
E
A
L
R
E
L
----
G
Y
R
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
38.70
22%
0
- C8 -
1MSZ
-
SMBP2_HUMAN
A:
[725-786]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
D
H
F
R
A
----
M
I
V
E
F
--
M
A
S
K
K
M
Q
L
E
F
P
P
S
L
-
N
S
H
--
D
R
L
R
V
H
Q
I
A
E
E
---------
H
G
-----
L
R
H
D
S
S
G
E
G
-
K
R
R
F
I
T
-
V
S
K
R
A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
38.03
13%
-51
- C8 -
2ASB
1
NUSA_MYCTU
A:
[158-220]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
P
---
A
R
F
V
---------------
A
N
---
A
L
S
P
A
K
V
-
V
-
S
V
S
V
I
D
Q
T
A
R
--
A
A
R
V
V
V
P
D
F
Q
L
S
L
---------
A
I
G
----
K
E
-
G
Q
N
A
R
L
A
A
R
L
-
T
G
W
R
I
D
I
-----------------
R
G
D
A
P
P
-----
P
P
P
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
37.10
27%
45
- C8 -
3GKU
-
?
A:
[78-206]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
I
-
S
V
E
Y
N
E
-
T
E
K
--
E
M
N
V
N
L
K
G
D
D
M
G
I
---------
L
I
G
----
K
R
-
G
Q
T
L
D
S
L
Q
Y
L
-
V
S
L
V
V
N
K
-----------------
S
S
S
D
Y
I
-----
R
V
K
L
----------
D
T
E
N
Y
R
E
R
R
K
--------------------
E
T
L
E
T
L
A
K
----
N
I
A
Y
K
--
V
K
R
T
K
R
S
V
S
L
E
P
M
N
-
P
Y
E
--
R
R
I
I
H
A
A
L
Q
N
D
---------
K
Y
-----
V
V
T
R
S
D
G
E
E
-
P
F
R
H
V
I
-
I
S
L
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------