@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0449: (2015-12-01 )
MIINSFDNSRKAIINPEDINSPIKGFPKTVITCFARETFNRILEELPHREIARTSVANLEIPIYELEFKEQKIGFFNAYVGASACVAILEDIIVFGMENLIVFGTCGVLDSSIEETSIIIPRSAIRDEGTSFHYSEASSEIAVNTKFHEEFKSFLDRQAVSYTEGKVWTTDGIYRETVDKMLEHKRNGAICVDMECSAIAALSKFRNINHFQFFYSADNLDAEVWEARSLGNSEDLEKKDKIAYIAMEFAIETF
Atome Classification :
(20 SA)
.........10........20........30........40...-..--...50........-60........70.....--...80---........90..-.---.-------------------------....100.......-110-.......120...-.-...---130.-.-..-..-------------------------.-----.140......--.150....---------..--.160.......170...-----------...--.180------------..-.--.-.--------.-.-..190.......200.......210.......220..-.-.....230---.--.......240.......250..-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
I
INSFDNSR
K
A
II
N
P
E
DINSPIKGF
P
K
T
V
I
T
C
F
A
R
E
T
F
N
R
I
L
E
-EL--P
H
R
E
I
A
RTSVAN
L
-
E
I
P
I
Y
E
L
E
FKEQK
I
G
F
F
--
N
A
Y
V
G
---
A
S
A
C
V
A
I
L
E
D
I
I
-
V
---
F
-------------------------GME
N
L
I
V
F
GTCGVL-DSS-IEE
T
S
I
I
I
PRSAI-R-DEG---T
S
-
F
-H-YS-EA-------------------------S-----S
E
I
A
V
N
T
K
F
H
--
E
E
F
K
S
F
L
D
---------
R
Q
--AVSYTEG
K
V
W
TTD
G
I
Y
R
-----------
E
T
V
--
D
K
--------------
M
L
-
E
--H-K--------R-N-G
A
I
C
V
DM
E
C
S
A
I
A
A
L
S
K
FRNI
N
H
F
Q
F
F
Y
SADNL-
D
A
E
-
V
-
W
E
A
RSLG----
N
--
S
E
D
L
E
K
KD
K
I
A
Y
I
A
M
E
F
AIETF-----
29
HHSearch
84.11
18%
-121
- C2 -
1JE0
2
PNPH_SULSO
A:
[10-235]
----------------------
K
G
E
V
A
E
R
V
L
V
V
G
D
P
G
R
A
R
L
L
S
T
-
L
L
--
Q
N
P
K
L
---
T
N
E
N
R
-
G
F
L
V
Y
T
G
K
Y
N
G
E
T
V
S
I
A
--
T
H
G
I
G
---
G
P
S
I
A
I
V
L
E
E
L
A
-
M
---
L
-------------------------
G
A
N
V
F
I
R
Y
G
T
T
G
A
L
-
V
P
Y
-
I
N
L
G
E
Y
I
I
V
T
G
A
S
Y
N
-
Q
G
G
---
L
F
-
Y
-
Q
-
Y
L
-
R
D
NA-----------------------
C
-----
V
A
S
T
P
D
F
E
L
T
--
N
K
L
V
T
S
F
S
---------
K
R
--
N
L
K
Y
Y
V
G
N
V
F
S
S
D
A
F
Y
A
-----------
E
D
E
--
E
F
--------------
V
K
-
K
--
W
-
S
--------
S
-
R
-
G
N
I
A
V
E
M
E
C
A
T
L
F
T
L
S
K
V
K
G
W
K
S
A
T
V
L
V
V
S
D
N
L
-
A
-------------------
E
E
L
E
K
S
V
M
D
G
A
K
A
V
L
D
T
L
T
S
-------
28
HHSearch
81.90
17%
-117
- C2 -
1Z34
1
?
A:
[9-235]
----------------------
V
G
D
F
A
E
T
V
L
M
C
G
D
P
L
R
A
K
L
I
A
E
T
Y
L
--
E
N
P
K
L
---
V
N
N
V
R
-
G
I
Q
G
Y
T
G
T
Y
K
G
K
P
I
S
V
M
--
G
H
G
M
G
---
L
P
S
I
C
I
Y
A
E
E
L
Y
-
S
T--
Y
-------------------------
K
V
K
T
I
I
R
V
G
T
C
G
A
I
-
D
M
D
-
I
H
T
R
D
I
V
I
F
T
S
A
G
-
T
-
N
S
K
---
I
N
-
R
I
R
-
F
M
-
D
H
-------------------------
D
-----
Y
P
A
T
A
S
F
D
V
V
--
C
A
L
V
D
A
A
K
---------
E
L
--
N
I
P
A
K
V
G
K
G
F
S
T
D
L
F
Y
N
-----------
P
Q
T
--
E
L
--------------
A
Q
-
L
--
M
-
N
--------
K
-
F
-
H
F
L
A
V
E
M
E
S
A
G
L
F
P
I
A
D
L
Y
G
A
R
A
G
C
I
C
T
V
S
D
H
I
-
L
H
H
-
E
E-----
R
Q
-----------
N
S
F
Q
N
M
M
K
I
A
L
E
A
A
I
K
L
------
1
PsiBlast_PDB
81.74
25%
-125
- C2 -
4LNH
2
?
A:
[40-216]
-----------------------------
V
I
V
C
G
E
P
D
R
V
N
R
I
V
E
-
L
M
--
D
N
V
E
L
L
---
A
E
N
R
-
E
Y
R
V
F
N
G
V
Y
K
G
T
T
I
T
I
C
--
S
T
G
I
G
---
A
P
S
M
I
I
A
V
E
E
L
K
-
L
---
C
-------------------------
G
A
T
H
V
I
R
V
G
S
A
G
A
M
-
Q
D
H
-
I
Q
L
G
E
L
I
V
A
E
G
A
V
-
R
-
D
E
G
---
G
S
-
K
-
A
-
Y
I
-
S
S
-------------------------
A
-----
Y
P
A
Y
A
S
F
A
L
L
--
K
E
I
S
H
F
L
E
---------
N
Q
--
S
V
K
Y
Y
F
G
V
V
R
S
H
D
S
F
Y
T
-----------
D
E
E
--
D
Q
--------------
L
C
-
Q
--
Y
W
N
--------
K
-
K
-
G
I
L
G
A
D
M
E
T
S
A
L
F
T
V
G
R
L
R
G
L
Q
V
A
S
I
L
N
N
V
V
L
Y
-
Q
V
N
-
Q
-
Y
V
N
D
N
K
A
----
M
--
M
N
G
E
R
L
A
A
I
T
A
L
E
T
L
C
K
Q
---------
21
HHSearch
80.92
16%
-108
- C2 -
3PHC
5
?
A:
[13-241]
----------------------
K
E
Q
I
T
P
V
V
L
V
V
G
D
P
G
R
V
D
K
I
K
V
-
V
C
--
D
S
Y
V
---
D
L
A
Y
N
R
-
E
Y
K
S
V
E
C
H
Y
K
G
Q
K
F
L
C
V
--
S
H
G
V
G
---
S
A
G
C
A
V
C
F
E
E
L
C
-
Q
---
N
-------------------------
G
A
K
V
I
I
R
A
G
S
C
G
S
L
-
Q
P
D
L
I
K
R
G
D
I
C
I
C
N
A
A
V
-
R
-
E
D
R
---
V
S
-
H
-
L
-
L
I
-
H
G
-------------------------
D
-----
F
P
A
V
G
D
F
D
V
Y
--
D
T
L
N
K
C
A
Q
---------
E
L
--
N
V
P
V
F
N
G
I
S
V
S
S
D
M
Y
Y
P
-----------
N
K
I
--
I
P
--------------
S
R
-
L
E
D
Y
-
S
--------
K
-
A
-
N
A
A
V
V
E
M
E
L
A
T
L
M
V
I
G
T
L
R
K
V
K
T
G
G
I
L
I
V
D
G
C
P
-
F
K
----
W
D
E
G
D
F
D
----
N
--
N
L
V
P
H
Q
L
E
N
M
I
K
I
A
L
G
A
C
A
K
L
A
-----
3
PsiBlast_PDB
80.54
25%
-127
- C2 -
4MCI
12
?
A:
[40-216]
-----------------------------
V
I
V
C
G
E
P
D
R
V
N
R
I
V
E
-
L
M
--
D
N
V
E
L
L
---
A
E
N
R
-
E
Y
R
V
F
N
G
V
Y
K
G
T
T
I
T
I
C
--
S
T
G
I
G
---
A
P
S
M
I
I
A
V
E
E
L
K
-
L
---
C
-------------------------
G
A
T
H
V
I
R
V
G
S
A
G
A
M
-
Q
D
H
-
I
Q
L
G
E
L
I
V
A
E
G
A
V
-
R
-
D
E
G
---
G
S
-
K
-
A
-
Y
I
-
S
S
-------------------------
A
-----
Y
P
A
Y
A
S
F
A
L
L
--
K
E
I
S
H
F
L
E
---------
N
Q
--
S
V
K
Y
Y
F
G
V
V
R
S
H
D
S
F
Y
T
-----------
D
E
E
--
D
Q
--------------
L
C
-
Q
--
Y
W
N
--------
K
-
K
-
G
I
L
G
A
D
M
E
T
S
A
L
F
T
V
G
R
L
R
G
L
Q
V
A
S
I
L
N
N
V
V
L
Y
-
Q
E
G
-
V
-
N
Q
Y
V
N
D
N
----
K
--
A
M
M
N
G
E
R
L
A
A
I
T
A
L
E
T
L
C
K
Q
-------
24
HHSearch
79.22
18%
-107
* C2 *
3UAW
5
DEOD_BACCE
A:
[9-234]
----------------------
Q
G
E
I
A
E
S
I
L
L
P
G
D
P
L
R
A
K
Y
I
A
E
-
T
F
--
L
E
D
V
-
T
C
-
Y
N
N
V
R
-
G
M
L
G
F
T
G
T
Y
K
G
K
R
V
S
V
Q
--
G
T
G
M
G
---
V
P
S
I
S
I
Y
V
N
E
L
I
Q
S
---
Y
-------------------------
G
V
K
N
L
I
R
V
G
T
C
G
A
I
-
Q
K
D
-
V
K
V
R
D
V
I
I
A
M
T
A
C
-
T
-
D
S
N
---
M
N
-
R
-
L
-
T
F
-
P
G
-------------------------
F
D----
F
A
P
A
A
N
F
D
L
L
--
K
K
A
Y
D
A
G
T
---------
E
K
--
G
L
H
V
R
V
G
N
V
L
T
A
D
V
F
Y
R
-----------
E
S
M
--
D
M
--------------
V
K
-
K
--
L
-
G
--------
D
-
Y
-
G
V
L
A
V
E
M
E
T
T
A
L
Y
T
L
A
A
K
Y
G
V
N
A
L
S
V
L
T
V
S
D
H
I
-
F
T
G
-
E
-
E
T
--
T
S
E
--------
E
R
Q
T
T
F
N
E
M
I
E
I
A
L
D
A
A
I
Q
-------
2
PsiBlast_PDB
79.00
25%
-127
- C2 -
4MCH
14
?
A:
[40-216]
-----------------------------
V
I
V
C
G
E
P
D
R
V
N
R
I
V
E
-
L
M
--
D
N
V
E
L
L
---
A
E
N
R
-
E
Y
R
V
F
N
G
V
Y
K
G
T
T
I
T
I
C
--
S
T
G
I
G
---
A
P
S
M
I
I
A
V
E
E
L
K
-
L
---
C
-------------------------
G
A
T
H
V
I
R
V
G
S
A
G
A
M
-
Q
D
H
-
I
Q
L
G
E
L
I
V
A
E
G
A
V
-
R
-
D
E
G
---
G
S
-
K
-
A
-
Y
I
-
S
S
-------------------------
A
-----
Y
P
A
Y
A
S
F
A
L
L
--
K
E
I
S
H
F
L
E
---------
N
Q
--
S
V
K
Y
Y
F
G
V
V
R
S
H
D
S
F
Y
T
-----------
D
E
E
--
D
Q
--------------
L
C
-
Q
--
Y
W
N
--------
K
-
K
-
G
I
L
G
A
D
M
E
T
S
A
L
F
T
V
G
R
L
R
G
L
Q
V
A
S
I
L
N
N
V
V
L
Y
-
Q
E
G
-
V
-
N
Q
Y
V
N
D
N
----
K
--
A
M
M
N
G
E
R
L
A
A
I
T
A
L
E
T
L
C
K
Q
-------
43
Fugue
78.34
14%
-103
- C2 -
1Q1G
6
?
A:
[5-247]
-------------
N
L
L
R
H
L
K
I
S
K
E
Q
I
T
P
V
V
L
V
V
G
D
P
G
R
V
D
K
I
K
V
-
V
C
--
D
S
Y
V
D
L
A
Y
N
---
R
-
E
Y
K
S
V
E
C
H
Y
K
G
Q
K
F
L
C
V
--
S
H
G
V
G
---
S
A
G
C
A
V
C
F
E
E
L
C
-
Q
---
N
-------------------------
G
A
K
V
I
I
R
A
G
S
C
G
S
L
Q
P
D
L
-
I
K
R
G
D
I
C
I
C
N
A
A
V
-
R
-
E
D
R
---
V
S
-
H
-
L
-
L
I
-
H
G
-------------------------
D
-----
F
P
A
V
G
D
F
D
V
Y
--
D
T
L
N
K
C
A
Q
---------
E
L
--
N
V
P
V
F
N
G
I
S
V
S
S
D
M
Y
Y
P
-----------
N
K
I
IP
S
R
--------------
L
E
-
D
--
Y
-
S
--------
K
-
A
-
N
A
A
V
V
E
M
E
L
A
T
L
M
V
I
G
T
L
R
K
V
K
T
G
G
I
L
I
V
D
G
C
P
-
F
K
W
----
D
E
G
D
F
D
----
N
--
N
L
V
P
H
Q
L
E
N
M
I
K
I
A
L
G
A
C
A
K
L
A
T
K
Y
A-
44
Fugue
72.42
15%
-105
- C2 -
1ECP
-
DEOD_ECOLI
A:
[1-237]
-----------
A
T
P
H
I
N
A
E
M
---
G
D
F
A
D
V
V
L
M
P
G
D
P
L
R
A
K
Y
I
A
E
-
T
F
LE
D
A
R
E
V
N
N
V
R
-----
G
M
L
G
F
T
G
T
Y
K
G
R
K
I
S
V
M
G
H----
G
MG
I
P
S
C
S
I
Y
T
K
E
L
I
T
-
D
---
F
-------------------------
G
V
K
K
I
I
R
V
G
S
C
G
A
V
-
L
P
H
-
V
K
L
R
D
V
V
I
G
M
G
A
C
-
T
-
D
S
K
V
N
R
I
R
-
F
-
K
----
D
H
-------------------------
D
-----
F
A
A
I
A
D
F
D
M
V
--
R
N
A
V
D
A
A
K
---------
A
L
G
I
--
D
A
R
V
G
N
L
F
S
A
D
L
F
Y
S
-----------
P
D
G
--
E
M
--------------
F
D
-
V
--
M
-
E
--------
K
-
Y
-
G
I
L
G
V
E
M
E
A
A
G
I
Y
G
V
A
A
E
F
G
A
K
A
L
T
I
C
T
V
S
D
H
I
-
R
T
------
H
E
Q
T
T
----------
A
A
E
R
Q
T
T
F
N
D
M
I
K
I
A
L
E
S
V
L
L
G
D
K
23
HHSearch
70.92
14%
-98
- C2 -
3MB8
6
?
A:
[17-246]
----------------------
K
E
D
V
E
P
V
V
I
I
V
G
D
P
A
R
T
E
E
V
A
N
-
M
C
--
E
K
K
Q
E
L
---
A
Y
N
R
-
E
Y
R
S
F
R
V
V
Y
D
S
Q
P
I
T
V
I
--
S
H
G
I
G
---
C
P
G
T
S
I
A
I
E
E
L
A
-
Y
---
L
-------------------------
G
A
K
V
I
I
R
A
G
T
C
G
S
L
-
K
P
K
T
L
K
Q
G
D
V
C
V
T
Y
A
A
V
-
N
-
E
T
G
---
L
I
-
S
-
N
-
I
L
-
P
E
-------------------------
G
-----
F
P
C
V
A
T
P
H
V
Y
--
Q
A
L
M
D
A
A
K
---------
E
L
--
G
I
E
A
A
S
G
I
G
V
T
Q
D
Y
F
Y
Q
-----------
N
G
I
--
L
P
--------------
S
K
-
L
--
E
M
Y
--------
S
-
K
-
C
C
D
V
I
D
M
E
M
S
G
V
L
G
L
C
Q
A
R
G
I
A
T
C
G
I
L
A
V
D
G
S
P
-
L
Q
----
W
D
E
G
D
Y
D
----
A
TG
V
K
A
T
T
G
K
E
N
M
V
K
I
T
L
K
A
C
A
N
L
R
-----
26
HHSearch
69.33
17%
-95
- C2 -
3QPB
3
?
A:
[41-275]
----------------------
P
G
D
V
G
R
Y
V
I
M
P
G
D
P
K
R
C
A
K
I
A
E
-
H
F
--
D
N
A
V
L
---
V
A
D
S
R
-
E
Y
V
T
Y
T
G
T
L
N
G
E
K
V
S
V
T
--
S
T
G
I
G
---
G
P
S
A
S
I
A
M
E
E
L
K
-
L
---
C
-------------------------
G
A
D
T
F
I
R
V
G
T
C
G
G
I
-
E
L
D
-
V
K
G
G
D
I
V
I
A
T
G
A
I
-
R
-
M
E
G
---
T
S
-
K
-
E
-
Y
A
-
P
I
-------------------------
E
-----
F
P
A
V
A
D
L
E
V
T
--
N
A
L
V
N
A
A
K
---------
K
L
--
G
Y
T
S
H
A
G
V
V
Q
C
K
D
A
F
Y
G
-----------
Q
H
E
--
P
E
RMPV
S
Y
E
L
L
-----
N
K
-
W
E
A
W
-
K
--------
R
-
L
-
G
T
K
A
S
E
M
E
S
A
A
L
F
V
A
A
S
H
L
G
V
R
C
G
S
D
F
L
V
V
G
N
Q
-
E
R
N
-
A
-
L
G
M
D
----------
N
P
M
A
H
D
T
E
A
A
I
Q
V
A
V
E
A
L
R
T
L
I
-----
27
HHSearch
68.99
14%
-110
- C2 -
3U40
3
?
A:
[18-242]
----------------------
Y
G
E
I
A
E
T
V
L
M
A
G
D
P
L
R
V
K
L
L
A
D
-
T
Y
--
L
T
D
V
-
V
Q
-
Y
N
S
V
R
-
G
A
V
G
Y
T
G
Y
Y
K
G
V
K
L
S
V
Q
--
A
H
G
M
G
---
M
P
S
I
G
I
Y
A
Y
E
L
F
-
N
F--
Y
-------------------------
G
V
K
R
I
I
R
I
G
S
A
G
A
F
-
D
E
S
-
L
K
L
G
D
I
V
I
G
M
G
A
C
-
Y
-
D
S
N
---
F
E
-
R
-
Q
-
Y
D
I
P
G
-------------------------
K
-----
Y
S
C
I
A
D
F
Q
L
C
--
R
E
A
V
D
A
A
E
---------
K
L
--
G
Y
R
Y
K
V
G
N
I
Y
S
A
N
Y
F
Y
D
-----------
D
G
D
--
H
S
--------------
G
A
----
W
-
K
--------
K
-
M
-
G
V
L
A
V
E
M
E
A
A
A
L
Y
M
I
A
A
R
A
R
K
Q
A
L
C
M
L
T
I
S
D
L
C
-
Y
G
S
-
G
-
E
K
M
T
A
---------
E
E
R
R
T
K
F
T
Q
M
M
E
V
A
L
S
L
A
K
--------
19
PsiBlast_PDB
66.59
22%
-73
- C2 -
3QPB
2
?
A:
[79-277]
-------------------------------------------------------------------
Y
T
G
T
L
N
G
E
K
V
S
V
T
--
S
T
G
I
G
---
G
P
S
A
S
I
A
M
E
E
L
K
-
L
---
C
-------------------------
G
A
D
T
F
I
R
V
G
T
C
G
G
I
-
E
L
D
-
V
K
G
G
D
I
V
I
A
T
G
A
I
-
R
-
M
E
G
---
T
S
-
K
-
E
-
Y
A
-
P
I
-------------------------
E
-----
F
P
A
V
A
D
L
E
V
T
--
N
A
L
V
N
A
A
K
---------
K
L
--
G
Y
T
S
H
A
G
V
V
Q
C
K
D
A
F
Y
G
Q
H
EPERMPV
S
Y
E
L
L
--
N
K
--------------
W
E
-
A
--
W
-
K
--------
R
-
L
-
G
T
K
A
S
E
M
E
S
A
A
L
-----
F
V
A
A
S
H
L
G
V
R
C
G
S
D
F
L
-
V
V
G
-
N
-
Q
E
R
N
A
L
G
M
D
N
P
M
--
A
H
D
T
E
A
A
I
Q
V
A
V
E
A
L
R
T
L
I
E
N
D
-----
4
PsiBlast_PDB
66.51
23%
-94
- C2 -
1JDT
2
PNPH_SULSO
A:
[47-221]
------------------------------------------------------------------
V
Y
T
G
K
Y
N
G
E
T
V
S
I
A
--
T
H
G
I
G
---
G
P
S
I
A
I
V
L
E
E
L
A
-
M
---
L
-------------------------
G
A
N
V
F
I
R
Y
G
T
T
G
A
L
-
V
P
Y
-
I
N
L
G
E
Y
I
I
V
T
G
A
S
-
Y
-
N
Q
G
---
G
L
-
F
-
Y
Q
Y
L
-
R
D
-------------------------
N
-----
A
C
V
A
S
T
P
D
F
E
L
T
N
K
L
V
T
S
F
S
---------
K
R
--
N
L
K
Y
Y
V
G
N
V
F
S
S
D
A
F
Y
A
-----------
E
D
E
--
E
F
--------------
V
K
-
K
--
W
-
S
--------
S
-
R
-
G
N
I
A
V
E
M
E
C
A
T
L
F
T
L
S
K
V
K
G
W
K
S
A
T
V
L
V
V
S
D
N
L
A
K
------
I
T
K
-----------
E
E
L
E
K
S
V
M
D
G
A
K
A
V
L
D
T
L
T
S
------
5
PsiBlast_PDB
65.73
23%
-97
- C2 -
1JDU
-
PNPH_SULSO
A:
[47-221]
------------------------------------------------------------------
V
Y
T
G
K
Y
N
G
E
T
V
S
I
A
--
T
H
G
I
G
---
G
P
S
I
A
I
V
L
E
E
L
A
-
M
---
L
-------------------------
G
A
N
V
F
I
R
Y
G
T
T
G
A
L
-
V
P
Y
-
I
N
L
G
E
Y
I
I
V
T
G
A
S
-
Y
-
N
Q
G
---
G
L
-
F
-
Y
Q
Y
L
-
R
D
-------------------------
N
-----
A
C
V
A
S
T
P
D
F
E
L
T
N
K
L
V
T
S
F
S
---------
K
R
--
N
L
K
Y
Y
V
G
N
V
F
S
S
D
A
F
Y
A
-----------
E
D
E
--
E
F
--------------
V
K
-
K
--
W
-
S
--------
S
-
R
-
G
N
I
A
V
E
M
E
C
A
T
L
F
T
L
S
K
V
K
G
W
K
S
A
T
V
L
V
V
S
D
N
L
A
K
-----
W
I
T
K
-----------
E
E
L
E
K
S
V
M
D
G
A
K
A
V
L
D
T
L
T
S
------
6
PsiBlast_PDB
65.45
23%
-97
- C2 -
1JE1
2
PNPH_SULSO
A:
[47-221]
------------------------------------------------------------------
V
Y
T
G
K
Y
N
G
E
T
V
S
I
A
--
T
H
G
I
G
---
G
P
S
I
A
I
V
L
E
E
L
A
-
M
---
L
-------------------------
G
A
N
V
F
I
R
Y
G
T
T
G
A
L
-
V
P
Y
-
I
N
L
G
E
Y
I
I
V
T
G
A
S
-
Y
-
N
Q
G
---
G
L
-
F
-
Y
Q
Y
L
-
R
D
-------------------------
N
-----
A
C
V
A
S
T
P
D
F
E
L
T
N
K
L
V
T
S
F
S
---------
K
R
--
N
L
K
Y
Y
V
G
N
V
F
S
S
D
A
F
Y
A
-----------
E
D
E
--
E
F
--------------
V
K
-
K
--
W
-
S
--------
S
-
R
-
G
N
I
A
V
E
M
E
C
A
T
L
F
T
L
S
K
V
K
G
W
K
S
A
T
V
L
V
V
S
D
N
L
A
K
---
I
-
W
I
T
K
-----------
E
E
L
E
K
S
V
M
D
G
A
K
A
V
L
D
T
L
T
S
------
25
HHSearch
65.41
17%
-87
- C2 -
3BJE
4
?
A:
[39-348]
----------------------
S
D
E
L
A
D
R
I
I
F
V
G
D
P
G
R
V
D
V
I
S
G
-
Y
F
--
D
K
D
S
-
I
R
A
S
R
D
H
R
-
E
I
R
F
A
T
G
T
Y
K
G
T
P
V
T
V
I
--
S
T
G
M
G
---
V
D
N
I
E
I
V
L
N
E
I
H
-
A
L
K
E
Y
DMERG
Q
W
R
H
R
KGDADAPSAGPFFDP
S
T
M
K
I
I
R
L
G
T
C
G
S
P
-
A
E
S
-
V
P
P
L
A
L
A
V
T
R
H
A
I
-
G
-
M
D
N
---
T
S
-
L
-
Y
-
Y
S
-
A
G
TRETS
K
D
Q
Q
E
I
R
R
I
V
R
E
QTGLRAID
I
-----
Y
T
S
M
A
H
P
N
I
T
--
K
S
I
C
A
A
C
D
A
H
N
A
A
T
GSE
A
D
--
K
Q
Q
Y
V
I
G
T
T
A
T
A
S
G
F
Y
G
-----------
C
Q
G
--
R
R
VGRFMKHLTVPN
M
V
E
E
-
L
--
G
-
S
LKFNLSNG
V
-
E
-
V
V
T
N
I
E
M
E
T
S
A
I
C
Y
L
S
D
M
L
G
Y
Q
A
G
A
A
C
V
V
V
S
K
R
-
V
G
E
-
K
-
K
M
F
L
G
---------
D
Q
L
D
A
A
M
K
R
C
I
K
I
I
L
E
A
L
V
S
A
------
34
HHSearch
65.06
17%
-100
- C2 -
3BL6
1
MTNN_STAAM
A:
[2-203]
--------------------------
M
M
I
G
I
I
G
A
M
E
E
E
V
T
I
L
K
N
-
K
L
--
T
Q
L
S
E
I
----
S
V
A
-
H
V
K
F
Y
T
G
I
L
K
D
R
E
V
V
I
T
--
Q
S
G
I
G
---
K
V
N
A
A
I
S
T
T
L
L
I
-
N
K
--
F
-------------------------
K
P
D
V
I
I
N
T
G
S
A
G
A
L
-
D
E
S
-
L
N
V
G
D
V
L
I
S
D
D
V
K
-
Y
H
D
A
D
---
A
T
A
F
-
G
-
Y
E
-
Y
G
-------------------------
Q
IPQMP
V
A
F
Q
S
S
K
P
L
I
--
E
K
V
S
Q
V
V
Q
---------
Q
Q
--
Q
L
T
A
K
V
G
L
I
V
S
G
D
S
F
I
G
-----------
S
V
E
--
Q
R
--------------
Q
K
-
I
--
K
-
K
--------
A
-
F
P
N
A
M
A
V
E
M
E
A
T
A
I
A
Q
T
C
Y
Q
F
N
V
P
F
V
V
V
R
A
V
S
D
L
A
-
N
G
E
-
A
-
E
M
S
F
E
A
F
----
L
--
E
K
A
A
V
S
S
S
Q
T
V
E
A
L
V
S
Q
L
---------
7
PsiBlast_PDB
64.53
23%
-98
- C2 -
1JPV
1
PNPH_SULSO
A:
[47-221]
------------------------------------------------------------------
V
Y
T
G
K
Y
N
G
E
T
V
S
I
A
--
T
H
G
I
G
---
G
P
S
I
A
I
V
L
E
E
L
A
-
M
---
L
-------------------------
G
A
N
V
F
I
R
Y
G
T
T
G
A
L
-
V
P
Y
-
I
N
L
G
E
Y
I
I
V
T
G
A
S
-
Y
-
N
Q
G
---
G
L
-
F
-
Y
Q
Y
L
-
R
D
-------------------------
N
-----
A
C
V
A
S
T
P
D
F
E
L
T
N
K
L
V
T
S
F
S
---------
K
R
--
N
L
K
Y
Y
V
G
N
V
F
S
S
D
A
F
Y
A
-----------
E
D
E
--
E
F
--------------
V
K
-
K
--
W
-
S
--------
S
-
R
-
G
N
I
A
V
E
M
E
C
A
T
L
F
T
L
S
K
V
K
G
W
K
S
A
T
V
L
V
V
S
D
N
L
A
K
G
G
-
I
-
W
I
T
K
-----------
E
E
L
E
K
S
V
M
D
G
A
K
A
V
L
D
T
L
T
S
------
31
HHSearch
63.67
15%
-91
- C2 -
1T8S
1
AMN_ECOLI
A:
[229-463]
----------------------------
I
A
L
S
C
A
G
G
N
W
I
T
A
E
T
E
-
A
P
--
E
E
A
I
-
S
D
L
A
W
K
K
H
Q
M
P
A
W
H
L
I
T
A
D
G
Q
G
I
T
L
V
--
N
I
G
V
G
---
P
S
N
A
K
T
I
C
D
H
L
A
-
V
---
L
-------------------------
R
P
D
V
W
L
M
I
G
H
C
G
G
L
-
R
E
S
-
Q
A
I
G
D
Y
V
L
A
H
A
Y
L
-
R
-
D
D
H
---
V
L
-
D
-
A
-
V
L
-
P
P
-------------------------
D
-----
I
P
I
P
S
I
A
E
V
Q
--
R
A
L
Y
D
A
T
K
L
VSGRPGE-
E
V
--
K
Q
R
L
R
T
G
T
V
V
T
T
D
D
R
N
W
-----------
E
L
R
--
Y
S
--------------
A
S
A
L
--
R
-
F
--------
N
L
S
-
R
A
V
A
I
D
M
E
S
A
T
I
A
A
Q
G
Y
R
F
R
V
P
Y
G
T
L
L
C
V
S
D
K
P
-
L
H
G
E
I
-
K
-----------------
G
A
I
S
E
H
L
Q
I
G
I
R
A
I
D
L
L
R
-----