@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0458: (2015-12-01 )
MLSFQIVEKPAMILAGVTLENVKSNQECPKLWEKLHKQYNPSKLKEKGIQQAIGICKTQPDFRFDYSATYRVETSVQAPKGLEIIRIPSATYAVISVKGPMPSSLQETWRKIIQGFFRENNLKPANSPNLEIYSSQHPQDTDYQMEIWLAIADITNKSKTNLI
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------....-.....10........20---..-.--.------.-.-----...30.----.......40...---------..--.-----------.---.50.......-.-60-----.-.......-----------------.70--.-....------------------..---.-------80--.........90...-...-..100.----.--------------......110.......120....---.-..-130..-..-.---.-------------------------------.140.......150.......160.-----------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------M
L
S
F
-
Q
I
VEKP
A
M
I
L
A
G
V
T
L
E
----NV-K--S------N-
Q
-----
E
C
P
K
L
W
----
E
K
L
H
KQY
N
P
S
K
L
---------
K
E
--
K
-----------
G
---
I
Q
Q
A
I
G
ICKT-Q-P------D-
F
R
F
DY
S
A
-----------------
T
Y
R
--
V
-
E
T
SV------------------QA---P-------K---G
L
E
I
I
RIPSA
T
Y
A
V
-
I
S
V-KGP-M
P
----
S
--------------
S
L
Q
E
T
W
R
K
I
I
Q
G
F
F
R
ENNLKPAN---S-P
N
-
L
E
I
Y
S-SQ-H---P-------------------------------QDTD
Y
Q
M
E
I
W
L
A
I
ADITNKSKTNLI-----------------------
5
HHSearch
96.41
18%
-80
- C4 -
3LUR
6
?
A:
[2-158]
---------------------------------------------------------------------------------------------------------------------------
M
E
Y
-
Q
L
Q
Q
L
A
S
L
T
L
V
G
I
K
E
T
----
Y
E
-
N
--
G
R
Q
A
---
Q
-
Q
-----
H
I
A
G
F
W
----
Q
R
C
Y
Q
E
G
V
I
A
D
L
---------
Q
L
--
K
-----------
N
NGD
L
A
G
I
L
G
L
C
I
P
-
E
-
L
------
D
-
G
K
M
S
Y
M
I
-----------------
A
V
T
--
G
-
D
N
S
A
-------------------
D
---
I
-------
A
---
K
Y
D
V
I
T
L
A
S
S
K
Y
M
V
-
F
E
A
-
Q
G
A
-
V
P
----
K
A
V
Q
Q
----------
K
M
E
E
V
H
H
Y
I
H
-
Q
Y
Q
---
A
N
T
V
K
S
---
A
-
P
F
-
F
E
L
Y
Q
-
D
G
-
D
---
T
-------------------------------
T
S
E
K
Y
I
T
E
I
W
M
P
V
K
G
---------------------------------
6
HHSearch
95.20
20%
-79
- C4 -
3GK6
1
?
A:
[20-170]
---------------------------------------------------------------------------------------------------------------------------
Q
G
M
-
N
I
S
E
I
N
G
F
E
V
T
G
F
V
V
R
----
T
T
-
N
--
A
D
E
M
NPM
T
-
A
-----
K
I
G
N
L
W
----
E
K
F
Y
L
N
A
-
A
P
K
L
---------
T
---------------
D
---
K
S
K
V
Y
G
L
Y
T
N
-
Y
-
E
SDF---
T
-
G
A
F
D
V
I
A
-----------------
C
S
D
--
T
-
L
S
P
-------------------
Q
L
---
L
-------
S
---
E
S
V
K
T
K
V
S
S
G
K
Y
V
T
-
F
S
A
-
T
G
E
M
P
-----
Q
--------------
V
V
I
D
L
W
N
E
V
W
-
N
Y
F
A
-
C
P
H
K
R
A
Y
---
T
-
T
D
-
F
E
Y
Y
K
-
S
A
-----------------------------------------
N
T
V
E
I
S
I
A
V
R
----------------------------------
16
Fugue
88.40
19%
-66
- C4 -
3GK6
1
?
A:
[15-170]
-----------------------------------------------------------------------------------------------------------------------ENL
Y
F
Q
G
M
N
I
S
E
I
N
G
F
E
V
T
G
F
V
V
R
T
T
N
A
D
E
M
N
--
P
M-----
T
-
A
-----
K
I
G
N
L
W
----
E
K
F
Y
L
N
A
A
P
K
L
T
---------
D
K
--
S
-----------
K
---
V
Y
G
L
Y
T
N
Y
E
S
-
D
-
F
------
T
-
G
A
F
D
V
I
A
-----------------
C
S
D
--
T
--
L
S
P
------------------
Q
L
---
L
-------
S
---
E
S
V
K
T
K
V
S
S
G
K
Y
V
T
-
F
S
A
-
T
G
E
-
M
P
----
Q
--------------
V
V
I
D
L
W
N
E
V
W
N
Y
F
--
A
C
P
H
K
R
A
Y
---
T
-
T
D
-
F
E
Y
Y
K
-
S
-----------------------------------------
A
N
T
V
E
I
S
I
A
V
R
----------------------------------
4
HHSearch
86.83
15%
-100
- C4 -
1JYH
-
SBMC_ECOLI
A:
[1-155]
---------------------------------------------------------------------------------------------------------------------------
M
N
Y
-
E
I
K
Q
E
E
K
R
T
V
A
G
F
H
L
V
----
G
P
-
W
--
E
--------
Q
-----
T
V
K
K
G
F
----
E
Q
L
M
M
W
V
D
S
K
N
I
-------------------------
V
---
P
K
E
W
V
A
V
Y
Y
D
-
N
-
P
DETP--
A
-
E
K
L
R
C
D
T
-----------------
V
V
T
--
V
-
P
G
Y
F
------------------
T
L
PEN
S
-------
E
---
G
V
I
L
T
E
I
T
G
G
Q
Y
A
V
-
A
V
A
-
R
V
V
-
G
-----
D
--------------
D
F
A
K
P
W
Y
Q
F
F
N
S
L
L
Q
D
S
A
Y
E
M
L
P
---
K
-
P
C
-
F
E
V
Y
L
-
N
N
-
G
---
A
-------------------------------
E
D
G
Y
W
D
I
E
M
Y
V
A
V
Q
P
K
--------------------------------
15
Fugue
83.20
16%
-77
- C4 -
1JYH
-
SBMC_ECOLI
A:
[1-155]
---------------------------------------------------------------------------------------------------------------------------
M
N
Y
-
E
I
K
Q
E
E
K
R
T
V
A
G
F
H
L
V
----
G
--
P
--
W
------
E
-
Q
-----
T
V
K
K
G
F
----
E
Q
L
M
M
W
V
D
S
K
N
I
---------
V
P
--
K
-----------------
E
W
V
A
V
Y
Y
D
-
N
-
P
------
D
-
E
T
P
A
E
K
L
-----------------
R
C
D
--
T
-
V
V
T
V
------------------
P
G
---
Y
FTLPENS
E
---
G
V
I
L
T
E
I
T
G
G
Q
Y
A
V
-
A
V
A
-
R
V
V
--
G
----
D
--------------
D
F
A
K
P
W
Y
Q
F
F
N
S
L
L
Q
D
S
A
Y
E
M
L
P
---
K
-
P
C
-
F
E
V
Y
L
-
N
N
-
G
---
A
-------------------------------
E
D
G
Y
W
D
I
E
M
Y
V
A
V
Q
P
K
--------------------------------
8
HHSearch
81.29
13%
-84
- C4 -
1D5Y
-
ROB_ECOLI
A:
[124-291]
---------------------------------------------------------------------------------------------------------------------------
P
E
H
-
K
F
V
T
L
E
D
T
P
L
I
G
V
T
Q
S
----
Y
S
-
C
S
L
E
------
Q
I
S
D
F
R
H
E
M
R
Y
Q
F
W
----
H
D
F
L
G
N
A
--------------
P
T
--------------
I
---
P
P
V
L
Y
G
L
N
E
T
-
R
-
P
S
QDKDD
E
-
Q
E
V
F
Y
T
T
-----------------
A
L
A
--
Q
-
D
Q
A
D
------------------
G
Y
---
V
-------
L
---
T
G
H
P
V
M
L
Q
G
G
E
Y
V
M
-
F
T
Y
-
E
G
L
-
G
-----
T
--------------
G
V
Q
E
F
I
L
T
V
Y
G
T
C
M
P
M
L
N
L
T
R
R
K
---
G
-
Q
D
-
I
E
R
Y
Y
-
P
A
-
E
D---D------------------------------
R
P
I
N
L
R
C
E
L
L
I
P
I
R
R
K
L
A
A
A
----------------------------
19
Fugue
80.13
14%
-80
* C4 *
1BOW
1
BMRR_BACSU
A:
[1-158]
-------------------------------------------------------------------------------------------------------------------------R
L
G
E
V
-
F
V
L
D
E
E
E
I
R
I
I
Q
T
E
A
E
----
G
I
-
G
--
P
------
E
-
N
-----
V
L
N
A
S
Y
----
S
K
L
K
K
F
I
E
S
N
N
--------------------------
S
---
Y
G
A
T
F
S
F
Q
P
Y
-
T
-
S
------
I
-
D
E
M
T
Y
R
H
-----------------
I
F
T
--
P
-
V
L
I
S
------------------
S
I
---
T
-------
P
---
D
M
E
I
T
T
I
P
K
G
R
Y
A
C
-
I
A
Y
-
N
F
S
--
P
----
E
--------------
H
Y
F
L
N
L
Q
K
L
I
K
-
Y
I
A
D
R
Q
L
-------
T
-
V
V
-
S
D
V
Y
E
-
L
I
-
I
---
P
-------------------------------
I
H
Y
E
Y
R
V
E
M
K
I
R
I
L
----------------------------------
9
HHSearch
77.77
15%
-88
- C4 -
3B49
2
?
A:
[23-211]
---------------------------------------------------------------------------------------------------------------------------
R
K
P
-
E
R
I
F
V
P
E
M
N
F
L
M
V
D
G
K
----
G
D
-
P
--
D
------
G
-
E
-----
E
Y
Q
K
A
V
----
Q
S
L
Y
A
I
A
Y
T
I
K
M
---------
S
K
--
M
GETRLDG
Y
S
D
F
V
---
V
P
P
L
E
G
F
W
W
S
E
G
K
F
DLKD--
R
-
D
A
W
L
W
T
S
-----------------
I
L
R
--
Q
-
P
D
F
V
T
E
E
V
L
E
W
A
K
E
V
A
R
K
K
KPD
V
D
---
T
-------
S
---
R
V
K
L
V
R
F
E
E
G
E
C
V
Q
-
M
M
H
-
V
G
P
-
F
-----
S
--------------
E
E
V
H
T
V
A
E
M
H
-
Q
F
M
E
T
E
G
L
R
N
D
T
GAI
R
-
K
H
-
H
E
I
Y
L
-
S
D
-
P
---
R
KA-----------------------------
N
P
E
K
M
K
T
I
L
R
L
P
V
S
----------------------------------
10
HHSearch
74.04
17%
-78
- C4 -
1R8E
9
BMRR_BACSU
A:
[123-277]
----------------------------------------------------------------------------------------------------------------------------
E
V
-
F
V
L
D
E
E
E
I
R
I
I
Q
T
E
A
E
----
G
I
-
G
--
P
------
E
-
N
-----
V
L
N
A
S
Y
----
S
K
L
K
K
F
I
E
S
--
A
---------
D
G
--------------
F
---
T
N
N
S
Y
G
A
T
F
S
-
F
-
Q
PYTSI-
D
-
E
M
T
Y
R
H
I
-----------------
F
T
P
--
V
-
L
T
N
K
QIS---------------
S
I
---
T
-------
P
---
D
M
E
I
T
T
I
P
K
G
R
Y
A
C
-
I
A
Y
-
N
F
S
-
P
-----
E
--------------
H
Y
F
L
N
L
Q
K
L
I
-
K
Y
I
A
D
R
Q
L
T
V
V
----
S
-
D
V
-
Y
E
L
I
I
-
P
I
-
H
YSP
K
-------------------------------
K
Q
E
E
Y
R
V
E
M
K
I
R
I
A
----------------------------------
17
Fugue
68.40
14%
-70
- C4 -
1D5Y
2
ROB_ECOLI
A:
[1-292]
Q
A
G
I
I
R
D
L
L
I
W
L
E
G
H
LDQ
P
L
S
L
DNVAAKAGYSKW
H
L
Q
R
M
F
K
D
V
TGHA
I
G
A
Y
I
R
A
R
R
L
S
K
S
A
V
A
L
R
L
T
ARP
I
L
D
I
A
L
Q
Y
RFDS
Q
Q
T
F
T
R
A
F
K
K
Q
FAQT
P
A
L
Y
R
R
SPEWSAFGIRPPLRL
G
E
F
T
M
P
E
H
-
K
F
V
T
L
E
D
T
P
L
I
G
V
T
Q
S
----
Y
S
-
C
--
S
------
L
-
E
-----
Q
I
S
D
F
R
----
H
E
M
R
Y
Q
F
W
H
D
F
L
---------
G
N
AP
T
-----------
I
---
P
P
V
L
Y
G
L
N
E
T
-
R
-
P
S
QDKDD
E
-
Q
E
V
F
Y
T
T
-----------------
A
L
A
--
Q
-
D
Q
A
D
------------------
G
Y
---
V
-------
L
---
T
G
H
P
V
M
L
Q
G
G
E
Y
V
M
-
F
T
Y
-
E
G
L
--
G
----
T
--------------
G
V
Q
E
F
I
L
T
V
Y
G
T
C
M
P
M
L
N
L
T
R
R
K
---
G
-
Q
D
-
I
E
R
Y
Y
-
P
A
E
D
---
D
-------------------------------
R
P
I
N
L
R
C
E
L
L
I
P
I
R
R
K
L
A
A
A
----------------------------
11
HHSearch
60.80
19%
-91
- C4 -
3R8J
1
HEBP2_HUMAN
A:
[128-201]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
---
D
V
F
I
E
D
R
A
E
M
T
V
F
V
-
R
S
F
-
D
G
F
-
S
S
A
---
Q
--------------
K
N
Q
E
Q
L
L
T
L
A
-
S
I
L
R
E
D
G
K
V
F
D
E
---
K
V
Y
Y
-
T
A
G
Y
N
-
S
P
-
V
---
K
--------------------------------
L
L
N
R
N
N
E
V
W
L
I
Q
K
N
---------------------------------
22
Fugue
57.56
18%
-50
- C3 -
1FSZ
-
?
?:
[232-356]
-----------------------------------------------------------------------------------------------------------------------------------------
I
N
V
D
F
A
----
D
V
-
K
--
A
------
V
-
M
-----
N
----------------------------------
N
-----------
G
---
G
L
A
M
I
G
I
G
E
S
-
D
-
S
------
E
-
K
R
A
K
E
A
V
-----------------
S
M
A
--
L
-
N
S
P
L
------------------
L
D
-------------------
V
D
I
D
G
A
T
G
A
L
-
I
H
V
-
M
G
P
-
E
D
----
L
--------------
T
L
E
E
A
-
R
E
V
V
A
T
V
S
-----
S
R
L
D
---
P
-
N
A
-
T
I
I
W
G
-
A
T
-
I
---
D
-------------------------------
E
N
L
E
N
T
V
R
V
L
L
V
I
T
G
V
Q
S
R
I
E
F
T
D
T
GLKRKKL----------------
3
PsiBlast_PDB
52.16
34%
-38
- C5 -
1N7D
1
LDLR_HUMAN
A:
[430-498]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
C
S
T
-
Q
-
L
------
D
--
R
A
H
G
-
S
-----------------
S
Y
D
T
V
I
-
S
R
D
I
-----------------------
P
-------
D
---
G
L
A
V
D
W
I
H
S
N
I
Y
W
T
-
D
S
V
-
L
G
T
-
V
--------------------
S
V
A
D
T
K
G
V
K
R
K
T
L
F
R
E
Q
G
S
K
P
R
A
---
I
-
V
V
-
D
P
V
H
G
-
F
M
-
Y
---
W
-------------------------------
T
D
W
G
T
P
A
K
I
K
K
G
G
L
N
G
V
D
I
Y
S
L
V
T
E
-----------------------
12
HHSearch
48.77
10%
-85
- C4 -
2GOV
-
HEBP1_MOUSE
A:
[118-189]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
---
S
V
K
I
E
E
R
E
G
I
T
V
Y
S
-
T
Q
F
-
G
G
Y
-
A
K
E
---
A
--------------
D
Y
V
A
H
A
T
Q
L
R
-
T
T
L
E
G
T
P
A
T
Y
Q
G
---
D
-
V
Y
Y
C
A
G
Y
D
-
P
P
-
M
---
K
--------------------------------
P
Y
G
R
R
N
E
V
W
L
V
K
A
----------------------------------
1
PsiBlast_PDB
48.18
36%
-40
* C5 *
3P5C
-
L:
[176-244]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
C
S
T
-
Q
-
L
------
D
-
R
A
H
G
V
S
S
-----------------
Y
D
T
--
V
I
S
R
D
I
------------------
Q
A
---
P
-------
D
---
G
L
A
V
D
W
I
H
S
N
I
Y
W
T
-
D
S
V
-
L
G
T
-
V
--------------------
S
V
A
D
T
K
G
V
K
R
K
T
L
F
R
E
N
G
S
K
P
R
A
---
I
-
V
V
-
D
P
V
H
G
-
F
M
-
Y
---
W
-------------------------------
T
D
W
G
T
P
A
K
I
K
K
G
G
L
N
G
V
D
I
Y
S
L
V
T
E
-----------------------
2
PsiBlast_PDB
47.91
36%
-78
- C2 -
1H4P
2
EXG1_YEAST
A:
[83-129]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
---
S
-------
Q
---
G
F
N
L
V
R
I
P
I
G
Y
W
A
F
Q
I
L
D
-
D
D
P
-
Y
V
----
S
--------------
G
L
Q
E
S
Y
L
D
Q
A
I
G
W
A
R
N
N
S
L
K
V
W
V
---
D
-
L
H
-
G
A
A
G
S
-
Q
N
-
G
---
F
-------------------------------
D
N
S
G
L
R
D
S
Y
K
F
L
E
D
S
N
L
A
V
T
I
N
V
L
N
-----------------------
7
HHSearch
46.70
12%
11
- C4 -
3E0H
-
?
A:
[6-158]
--------------------------------------------------------------------------------------------------------------------------
Q
F
V
C
-
E
L
K
E
L
A
P
V
P
A
L
L
I
R
T
Q
----
T
T
-
M
--
S
--------------
E
L
G
S
L
F
E
A
G
Y
H
D
I
L
Q
L
L
A
G
Q
G
K
---------
S
---------------
P
---
S
G
P
P
F
A
R
Y
F
G
-
M
-
S
------
A
-
G
T
F
E
V
E
F
-----------------
G
F
P
--
V
-
E
G
G
V
------------------
E
G
---
S
-------
G
---
R
V
V
T
G
L
T
P
S
G
K
A
A
S
-
S
L
Y
-
I
G
P
-
Y
-----
G
--------------
E
I
E
A
V
Y
D
A
L
M
-
K
W
V
D
D
N
G
F
D
L
S
----
G
-
E
A
-
Y
E
I
Y
L
-
D
N
-
P
AE-
T
-------------------------------
A
P
D
Q
L
R
T
R
V
S
L
M
L
H
E
S
--------------------------------
21
Fugue
36.63
11%
-14
* C3 *
1WYZ
-
?
A:
[2-234]
------------------------------------------------------------------------------------------------------------ETALYL
L
P
V
T
LGDT
P
L
E
Q
-
V
L
P
S
Y
N
T
E
I
I
R
G
I
R
H
F
----
I
V
-
E
--
D
------
V
-
R
-----
S
A
R
R
F
L
----
K
K
V
D
R
E
I
D
I
D
S
L
T
F
Y
P
L
N
KHT
S
P
--
E
-----------
D
---
I
S
G
Y
L
K
P
L
A
G
-
G
-
A
------
S
M
G
V
I
S
E
D
P
-----------------
G
A
D
--
V
-
V
A
I
A
------------------
Q
R
-----------
Q
---
K
L
K
V
I
P
L
V
G
P
S
S
I
I
-
L
S
V
M
A
S
G
-
F
N
----
G
Q
S
F
A
F
HGYLPIEP
G
E
R
A
K
K
L
K
T
L
E
Q
R
V
Y
A
E
S
Q
T
Q
L
F
I
---
E
-
T
P
-
Y
R
N
H
K
M
I
E
-
D
---
I
-------------------------------
L
Q
N
C
R
P
Q
T
K
L
C
I
A
A
N
I
T
C
E
G
E
F
I
Q
T
R
T
VKDWKGHIPK
I
P
C
I
F
L
L
Y
K--
20
Fugue
28.70
12%
18
- C1 -
4OPB
17
?
A:
[4-233]
-------------------------------------------------------------------------------------------------------------------------------
G
Y
M
Y
I
P
S
S
R
T
R
L
G
H
E
A
----
G
I
-
D
--
S
------
C
-
P
-----
E
C
A
I
L
E
----
P
V
---
S
S
W
P
D
-
L
---------
D
A
--
A
-----------
P
---
V
G
R
S
-
G
P
C
G
Y
-
N
-
A
------
R
-
D
S
I
D
Y
N
Q
PTTNWGSDAV
Q
S
Y
S
PGE
E
I
E
--
V
-
Q
W
C
V
------------------
D
H
---
N
-------
G
DH
G
G
M
F
T
Y
R
I
C
Q
D
Q
S
I
V
-
D
K
F
-
L
D
P
-
S
Y
L
P
T
N
D
--------------
E
K
Q
A
A
E
D
C
F
D
A
G
L
L
P
C
T
D
V
S
G
Q
E
---
C
-
G
Y
-
S
A
D
C
T
-
E
G
-
E
---
A
CWRND
W
F
T
C
N
GFEASDRPKCQGVDNAELNSC
Y
T
S
I
A
G
G
Y
T
V
T
K
K
V
K
L
P
E
Y
T
S
N
H
T
L
I
S
F
K
W
N
S
FQTG
Q
I
Y
L
S
C
A
D
I
A
I
Q
13
HHSearch
13.32
0%
177
- C4 -
1RIJ
-
?
A:
[3-14]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
L
L
G
Q
W
L
K
D
G
G
P
S
S
G
R
---
P
-
P
P
-
S
--------------------------------------------------------------------------------------------