@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0476: (2015-12-01 )
MGDFAGDQEFCTNSVPHVSDNGNPTSGHQAEQGVFDNQESNFSSDYNLSQVSDFERNNLYSQSFGASLDNSEPLGKHSPMNFSKPSQMTESIDHDVHYDLPGVNEEMESPFQSESDYQSQNSSIIVETPEMDDMIYQSSQKKNISIGNNYSSDKKSLENSFDSPIIPERSEPETDAKERFNPQAEYQRLKAKRQKPLGNRKKSKLEAELGQFTDDASYYKAHGGTAFKRGFNASKSKELRLKQNLERKATILAELDKLRGHV
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------....-----.....10........20........30.--.......40........50........60.-......-------.70........-----80........90.-..--------.---....100-----.......110---------.......120---.------------.......130--........140.....-..150.......160...---....170...---....180----..-------......190.......--------200--.......210.......220......--.230....------...240----.......250.-......260
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------MGDF-----AG
D
Q
E
F
CTNSVPHVSDNGNPTSGH
Q
A
EQ--GVFDNQESNFSSDYN
L
S
Q
V
SDFERNNLY
S
Q
-SFGASL-------DNSEPLGKHSP-----MNFS
K
P
S
Q
M
T
E
S
I-DH--------D---VHYDLPG-----V
N
E
E
M
ESPFQ---------SESDYQSQN----S------------
S
I
I
V
ETPEM---
D
D
M
I
Y
QSSQKK
N
I
SIG-NNYS
S
D
K
K
S
L
E
NSFDSPI---IPERSEPET
D
---
A
K
ERF
N
-----
P
Q
-------
A
E
Y
Q
R
L
K
A
K
R
QKPLGN--------
R
K
K
--
S
K
L
E
A
E
L
GQFTDDAS
Y
Y
KAHGG
T
A
F
K
--RGFNASKS------
K
E
L
R
L
K
----
Q
N
L
E
R
K
A
T
I
L
A
-
E
L
D
K
LRGHV
29
Fugue
70.13
17%
47
- C1 -
4LDV
13
ARFA_ARATH
A:
[16-356]
-------------------------------------------------------------------S
D
A
L
C
R
E
L
W
H
A
C
A
G
P
L
V
T
L
P
R
E
G
E
R
V
Y
Y
F
P
E
G
H
M
E
Q
L
E
A
S
M
H
Q
G
L
E
Q
Q
M
--
P
S
F
N
L
P
S
K
I
L
C
K
V
I
N
I
Q
R
R
A
--
E
T
D
E
V
Y
A
Q
I
T
L
L
P
E
L
-------
D
Q
S
E
P
T
S
P
D
A
P
VQET
V
H
S
F
C
K
T
L
T
A
S
D
T
S
-
T
H
G
G
F
S
V
L
R
R
H
---
A
D
D
C
L
P
P
-----
L
D
M
S
Q
Q
P
P
W
Q
E
L
V
A
T
D
LHN
S
E
W
H
F
R
H
I
F
----
R
G
QP
R
R
H
L
L
T
TG
W
S
V
F
V
S
S
K
K
L
VAG
D
A
F
I
F
L
R
G
E
N
E
E
L
R
V
G
V
R
R
H
M
P
S
S
V
I
S
S
H
S
M
H
I
G
V
---
L
A
T
A
A
H
A
I
T
T
G
T
I
F
S
V
F
Y
K
-----
P
R
TSRSEFI
V
S
V
N
R
Y
L
E
A
K
T
Q
K
L
S
V
--------
G
M
R
--
F
K
M
R
------------
F
K
R
F
S
G
T
I
V
G
--
V
Q
E
N
K
S
S
V
WHDSEW
R
S
L
K
V
Q
W
DEP
S
S
V
F
R
P
E
R
V
S
P
W
E
L
E
P
L
N
---
22
Fugue
64.67
17%
49
- C3 -
4O5J
3
?
A:
[27-400]
LKN
L
N
E
K
Y
E
Q
L
S
Q
Y
L
N
Q
V
A
S
L
K
Q
S
I
Q
N
A
N
N
I
E
L
V
N
S
S
L
N
Y
L
K
S
F
T
N
N
N
Y
NSTTQS
P
I
F
N
A
V
Q
A
V
I
T
S
V
L
G
F
W
S
L
Y
AGNY
F
T
F
F
-----
V
G
K
K
---
V
D
S
G
Q
P
A
S
V
Q
G
N
P
P
F
K
T
I
I
E
N
CS
G
I
E
N
C
A
M
D
Q
T
T
Y
D
K
M
K
K
L
A
E
D
L
Q
A
A
Q
T
N
S
A
-
T
K
G
N
N
L
CALSGCA
A
T
S
N
P
P
N
S
T
V
S
-----
N
A
L
N
L
A
Q
Q
L
M
D
L
I
-
A
N
--------
T
K
T
A
M
M
W
K
N
I
V
-----
I
S
G
V
S
N
T
S
G
A
---------
I
T
S
T
N
Y
P
T
Q
Y
A
V
F
N
------------
N
I
K
A
M
I
P
I
L
---
Q
Q
A
V
T
L
S
Q
S
N
H
T
L
S
A
S
-
L
Q
A
Q
A
T
G
S
Q
T
N
P
K
F
A
K
D
I
Y
T
F
A
Q
N
Q
K
Q
V
I
S
Y
---
A
Q
D
I
F
N
L
F
N
S
I
P
A
-------
E
Q
Y
K
Y
L
E
K
A
Y
L
K
I
P
N
A
GSTPTNPY
R
Q
V
--
V
N
L
N
Q
E
V
Q
T
I
K
N
N
V
S
Y
Y
G
N
R
V
D
A
A
L
S
V
A
R
D
V
Y
N
L
K
S
------
N
Q
A
E
I
V
----
T
A
Y
N
D
A
K
T
L
S
E
-
E
I
S
K
L
P
H
--
5
PsiBlast_PDB
56.51
24%
0
- C4 -
2OA1
1
REBH_NOCAE
B:
[185-285]
-----------------------------------------------------------------------------------------------------------------------------
T
N
Y
A
W
H
F
D
A
H
L
V
A
D
F
L
R
R
-
F
A
T
E
-
K
L
G
V
R
H
VE-----
D
R
V
E
H
V
Q
R
D
A
N
-----
G
N
I
E
S
V
R
T
A
T
G
R
V
F
D
A
--------
D
---
L
F
V
D
C
S
G
FRGLL
I
N
K
A
M
E
E
P
F
L
---------
D
M
S
D
H
L
L
N
D
----
S
------------
A
V
A
T
Q
V
P
H
D
---
D
D
A
N
G
V
E
P
F
T
S
A
I
A
M
K
-
S
G
W
T
W
K
I
P
M
L
G
R
F
G
T
G
Y
V
---
Y
S
S
R
F
A
T
E
D
E
---
A
V
R
E
F
C
-----
E
M
-------
W
H
L
D
P
E
T
Q
P
L
N
R
I
R
F
R
--------
V
G
R
--
N
R
R
A
W
V
G
N
C
V
S
I
G
T
S
S
C
F
V
E
P
L
E
S
T
G
--
I
Y
F
V
Y
A
A
L
------
Y
Q
L
V
K
H
----
F
P
D
K
S
L
N
P
V
L
T
-
A
R
F
N
R
E
I
E
T
3
PsiBlast_PDB
56.37
24%
9
- C4 -
2OAM
-
REBH_NOCAE
A:
[165-265]
-----------------------------------------------------------------------------------------------------------------------------
T
N
Y
A
W
H
F
D
A
H
L
V
A
D
F
L
R
R
-
F
A
T
E
-
K
L
G
V
R
H
V
E
-----
D
R
V
E
H
V
Q
R
D
A
N
-----
G
N
I
E
S
V
R
T
A
T
G
R
V
F
D
A
--------
D
---
L
F
V
D
C
S
G
FRGLL
I
N
K
A
M
E
E
P
F
L
---------
D
M
S
D
H
L
L
N
D
----
S
------------
A
V
A
T
Q
V
P
H
D
---
D
D
A
N
G
V
E
P
F
T
S
A
I
A
M
K
-
S
G
W
T
W
K
I
P
M
L
G
R
F
G
T
G
Y
V
---
Y
S
S
R
F
A
T
E
D
E
---
A
V
R
E
F
C
-----
E
M
-------
W
H
L
D
P
E
T
Q
P
L
N
R
I
R
F
R
--------
V
G
R
--
N
R
R
A
W
V
G
N
C
V
S
I
G
T
S
S
C
F
V
E
P
L
E
S
T
G
--
I
Y
F
V
Y
A
A
L
------
Y
Q
L
V
K
H
----
F
P
D
K
S
L
N
P
V
L
T
-
A
R
F
N
R
E
I
E
T
2
PsiBlast_PDB
56.27
24%
8
- C4 -
2OAL
1
REBH_NOCAE
A:
[185-285]
-----------------------------------------------------------------------------------------------------------------------------
T
N
Y
A
W
H
F
D
A
H
L
V
A
D
F
L
R
R
-
F
A
T
E
-
K
L
G
V
R
H
V
E-----
D
R
V
E
H
V
Q
R
D
A
N
-----
G
N
I
E
S
V
R
T
A
T
G
R
V
F
D
A
--------
D
---
L
F
V
D
C
S
G
FRGLL
I
N
K
A
M
E
E
P
F
L
---------
D
M
S
D
H
L
L
N
D
----
S
------------
A
V
A
T
Q
V
P
H
D
---
D
D
A
N
G
V
E
P
F
T
S
A
I
A
M
K
-
S
G
W
T
W
K
I
P
M
L
G
R
F
G
T
G
Y
V
---
Y
S
S
R
F
A
T
E
D
E
---
A
V
R
E
F
C
-----
E
M
-------
W
H
L
D
P
E
T
Q
P
L
N
R
I
R
F
R
--------
V
G
R
--
N
R
R
A
W
V
G
N
C
V
S
I
G
T
S
S
C
F
V
E
P
L
E
S
T
G
--
I
Y
F
V
Y
A
A
L
------
Y
Q
L
V
K
H
----
F
P
D
K
S
L
N
P
V
L
T
-
A
R
F
N
R
E
I
E
T
1
PsiBlast_PDB
56.25
24%
13
- C4 -
2E4G
-
REBH_NOCAE
A:
[185-285]
-----------------------------------------------------------------------------------------------------------------------------
T
N
Y
A
W
H
F
D
A
H
L
V
A
D
F
L
R
R
-
F
A
T
E
-
K
L
G
V
R
H
V
E
-----
D
R
V
E
H
V
Q
R
D
A
N
-----
G
N
I
E
S
V
R
T
A
T
G
R
V
F
D
A
--------
D
---
L
F
V
D
C
S
G
FRGLL
I
N
K
A
M
E
E
P
F
L
---------
D
M
S
D
H
L
L
N
D
----
S
------------
A
V
A
T
Q
V
P
H
D
---
D
D
A
N
G
V
E
P
F
T
S
A
I
A
M
K
-
S
G
W
T
W
K
I
P
M
L
G
R
F
G
T
G
Y
V
---
Y
S
S
R
F
A
T
E
D
E
---
A
V
R
E
F
C
-----
E
M
-------
W
H
L
D
P
E
T
Q
P
L
N
R
I
R
F
R
--------
V
G
R
--
N
R
R
A
W
V
G
N
C
V
S
I
G
T
S
S
C
F
V
E
P
L
E
S
T
G
--
I
Y
F
V
Y
A
A
L
------
Y
Q
L
V
K
H
----
F
P
D
K
S
L
N
P
V
L
T
-
A
R
F
N
R
E
I
E
T
4
PsiBlast_PDB
55.38
24%
16
- C4 -
2O9Z
1
REBH_NOCAE
A:
[185-285]
-----------------------------------------------------------------------------------------------------------------------------
T
N
Y
A
W
H
F
D
A
H
L
V
A
D
F
L
R
R
-
F
A
T
E
-
K
L
G
V
R
H
V
E
-----
D
R
V
E
H
V
Q
R
D
A
N
-----
G
N
I
E
S
V
R
T
A
T
G
R
V
F
D
A
--------
D
---
L
F
V
D
C
S
G
FRGLL
I
N
K
A
M
E
E
P
F
L
---------
D
M
S
D
H
L
L
N
D
----
S
------------
A
V
A
T
Q
V
P
H
D
---
D
D
A
N
G
V
E
P
F
T
S
A
I
A
M
K
-
S
G
W
T
W
K
I
P
M
L
G
R
F
G
T
G
Y
V
---
Y
S
S
R
F
A
T
E
D
E
---
A
V
R
E
F
C
-----
E
M
-------
W
H
L
D
P
E
T
Q
P
L
N
R
I
R
F
R
--------
V
G
R
--
N
R
R
A
W
V
G
N
C
V
S
I
G
T
S
S
C
F
V
E
P
L
E
S
T
G
--
I
Y
F
V
Y
A
A
L
------
Y
Q
L
V
K
H
----
F
P
D
K
S
L
N
P
V
L
T
-
A
R
F
N
R
E
I
E
T
7
PsiBlast_PDB
52.97
22%
71
- C4 -
3GTY
-
TIG_THEMA
X:
[307-414]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-----
R
Y
E
Q
I
V
S
S
Y
E
---------
S
E
E
K
F
R
E
E
L
----
K
------------
E
R
I
L
D
D
I
K
R
---
D
R
V
I
E
V
L
A
Q
E
K
G
I
S
V
N
-
D
E
E
L
E
K
E
A
E
E
L
A
P
F
W
G
-
I
---
S
P
D
R
A
K
S
L
V
K
---
A
R
Q
D
L
R
-----
E
E
-------
L
R
W
A
I
L
K
R
K
V
L
D
L
L
L
Q
--------
E
V
K
--
V
K
V
V
E
P
K
G
-----------------------------------------------------------------
6
PsiBlast_PDB
49.93
31%
-41
- C4 -
4LU6
1
REBH_NOCAE
A:
[239-285]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
-
D
A
--------
D
---
L
F
V
D
C
S
G
FRGLL
I
N
K
A
M
E
E
P
F
L
---------
D
M
S
D
H
L
L
N
D
----
S
------------
A
V
A
T
Q
V
P
H
D
---
D
D
A
N
G
V
E
P
F
T
S
A
I
A
M
K
-
S
G
W
T
W
K
I
P
M
L
G
R
F
G
T
G
Y
V
---
Y
S
S
R
F
A
T
E
D
E
---
A
V
R
E
F
C
-----
E
M
-------
W
H
L
D
P
E
T
Q
P
L
N
R
I
R
F
R
--------
V
G
R
--
N
R
R
A
W
V
G
N
C
V
S
I
G
T
S
S
C
F
V
E
P
L
E
S
T
G
--
I
Y
F
V
Y
A
A
L
------
Y
Q
L
V
K
H
----
F
P
D
K
S
L
N
P
V
L
T
-
A
R
F
N
R
E
I
E
T
10
PsiBlast_CBE
47.40
32%
-20
- C4 -
4LU6
1
REBH_NOCAE
B:
[240-285]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
--------
D
---
L
F
V
D
C
S
G
FRGLL
I
N
K
A
M
E
E
P
F
L
---------
D
M
S
D
H
L
L
N
D
----
S
------------
A
V
A
T
Q
V
P
H
D
---
D
D
A
N
G
V
E
P
F
T
S
A
I
A
M
K
-
S
G
W
T
W
K
I
P
M
L
G
R
F
G
T
G
Y
V
---
Y
S
S
R
F
A
T
E
D
E
---
A
V
R
E
F
C
-----
E
M
-------
W
H
L
D
P
E
T
Q
P
L
N
R
I
R
F
R
--------
V
G
R
--
N
R
R
A
W
V
G
N
C
V
S
I
G
T
S
S
C
F
V
E
P
L
E
S
T
G
--
I
Y
F
V
Y
A
A
L
------
Y
Q
L
V
K
H
----
F
P
D
K
S
L
N
P
V
L
T
-
A
R
F
N
R
E
I
E
T
9
PsiBlast_PDB
45.64
21%
68
- C4 -
3GU0
-
TIG_THEMA
A:
[307-396]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-----
R
Y
E
Q
I
V
S
S
Y
E
---------
S
E
E
K
F
R
E
E
L
----
K
------------
E
R
I
L
D
D
I
K
R
---
D
R
V
I
E
V
L
A
Q
E
K
G
I
S
V
N
-
D
E
E
L
E
K
E
A
E
E
L
A
P
F
W
G
-
I
---
S
P
D
R
A
K
S
L
V
K
---
A
R
Q
D
L
R
-----
E
E
-------
L
R
W
A
I
L
K
R
K
V
L
D
L
L
L
Q
--------
E
V
E
---------------------------------------------------------------------------
8
PsiBlast_PDB
43.72
21%
73
- C4 -
2NSA
3
A:
[65-154]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-----
R
Y
E
Q
I
V
S
S
Y
E
---------
S
E
E
K
F
R
E
E
L
----
K
------------
E
R
I
L
D
D
I
K
R
---
D
R
V
I
E
V
L
A
Q
E
K
G
I
S
V
N
-
D
E
E
L
E
K
E
A
E
E
L
A
P
F
W
G
-
I
---
S
P
D
R
A
K
S
L
V
K
---
A
R
Q
D
L
R
-----
E
E
-------
L
R
W
A
I
L
K
R
K
V
L
D
L
L
L
Q
--------
E
V
E
--
H
H
H
H
---------------------------------------------------------------------
23
Fugue
42.48
24%
11
- C4 -
3BJ4
1
KCNQ1_HUMAN
A:
[12-48]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
T
I
G
--
A
R
L
N
R
V
E
D
------
K
V
T
Q
L
D
----
Q
R
L
A
L
I
T
D
M
L
H
-
Q
L
L
S
L
H
G
--
21
Fugue
39.92
14%
34
- C4 -
2A3D
-
?
A:
[1-73]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
S
W
A
-----
E
F
-------
K
Q
R
L
A
A
I
K
T
R
L
Q
A
L
G
G
--------
S
E
A
EL
A
A
F
E
K
E
I
A
A
F
E
S
E
L
Q
A
Y
K
G
K
G
N
P
E
V
E
--
A
L
R
K
E
A
A
A
------
I
R
D
E
L
Q
----
A
Y
R
H
N
----------------
26
Fugue
38.00
30%
67
- C4 -
2MLP
1
?
?:
[1-26]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
L
---
K
A
S
E
F
G
-----
V
V
-------
L
S
V
D
A
L
K
L
S
R
Q
S
P
L
G
---------------------------------------------------------------------------------------
13
HHSearch
37.80
15%
40
- C4 -
3LAY
-
ZRAP_SALTY
A:
[77-109]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
--
A
L
L
T
A
S
S
P
------
D
T
A
K
I
N
----
A
V
A
K
E
M
E
S
L
G
Q
-
K
L
D
E
Q
R
---
27
Fugue
35.91
13%
52
- C4 -
1FE6
-
?
A:
[1-52]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
I
I
---
N
E
T
A
D
D
-----
I
V
-------
Y
R
L
T
V
I
I
D
D
R
Y
E
S
L
K
N
--------
L
I
T
--
L
R
A
D
R
L
E
M
I
I
N
D
N
V
S
T
I
L
A
S
G
----------------------------------------------------
20
Fugue
34.54
37%
51
- C4 -
4BXT
3
?
A:
[13-36]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
------
I
E
A
R
L
E
----
S
I
E
E
K
L
S
M
I
L
G
-
L
L
R
T
L
----
28
Fugue
33.99
23%
115
* C4 *
4MQV
-
SMAL1_HUMAN
B:
[1-26]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-----
T
E
-------
E
Q
R
K
K
I
E
E
N
R
Q
K
A
L
A
R
--------
R
A
E
--
K
L
L
A
---------------------------------------------------------------------
12
HHSearch
33.20
13%
61
- C4 -
2WQ1
3
A:
[6-29]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
K
I
E
----
E
N
T
S
K
I
Y
H
N
T
N
-
E
I
A
R
N
T
K
L
V