@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0602: (2015-12-02 )
MNYHDYIWDLGGTLLDNYESSTRAFVETLKEFGYQADHDSVYQKLKESTADAIAYFIPEEADFLKEYKANEAKVLETPILFQGAKELLAKIQRQGSRNFLVSHRDNQVIVILEKTEIIDYFTEVVTADNGFSRKPSPESMLYLKEKYQIDNCLVIGDRDIDKQAGESAGFDTLLVDGSKSLMEIIE
Atome Classification :
(20 SA)
.........10........20.........30..---...--..-.40.-..--------..-.--------..50---------------....-----------------.-------.------.---.-------60--------------.---------.------.----.....---.----70.-..-.---.....80.........90........100......-.--110.-......120.-.......--130.-......140.....--..----150.......160.......170.-......180....-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNY
H
D
Y
I
W
D
L
G
G
T
L
L
DNYE
S
-
S
T
R
A
F
V
E
T
L
K
EFG---YQA--
D
H
-
D
S
V
Y
-
Q
K
--------
L
K
-
E
--------STAD---------------
A
I
A
Y
-----------------F-------I------P---
E
-------
E
---------------
A
---------
D
------
F
----
L
K
E
YK---A----N-E-
A
K
-V---LET
P
I
L
-
F
Q
G
A
K
E
L
L
A
K
I
Q
R
QGSR
N
F
L
V
SHRD
N
Q
V
-
I
--
V
I
L
E-K
T
E
I
I
D
Y
F
-
T
-
E
V
V
TADN--GFSR-KPSP
E
S
M
L
Y
L
K
E
KY--QI----D
N
C
L
V
IGDRD
I
D
K
QAGESAGF
D
T
L
-
L
VDG
S
K
S
L
M
E
I
IE-
46
Fugue
98.05
62%
-107
- C1 -
2FI1
1
?
A:
[4-190]
M
K
Y
H
D
Y
I
W
D
L
G
G
T
L
L
D
N
Y
E
T
-
S
T
A
A
F
V
E
T
L
A
L
Y
G
---
I
T
Q
--
D
H
-
D
S
V
Y
-
Q
A
--------
L
K
-
V
--------
S
T
P
F
---------------
A
I
E
T
-----------------
F
-------
A
------
P
---
N
-------
L
---------------
E
---------
N
------
F
----
L
E
K
Y
K
---
E
----
N
-
E
-
A
R
-
E
---
L
E
H
P
I
L
-
F
E
G
V
S
D
L
L
E
D
I
S
N
Q
G
G
R
H
F
L
V
S
H
R
N
D
Q
V
-
L
--
E
I
L
E
-
K
T
S
I
A
A
Y
F
-
T
-
E
V
V
T
S
S
S
--
G
F
K
R
-
K
P
N
P
E
S
M
L
Y
L
R
E
K
Y
--
Q
I
----
S
S
G
L
V
I
G
D
R
P
I
D
I
E
A
G
Q
A
A
G
L
D
T
H
-
L
F
T
S
I
V
N
L
R
Q
V
L
D
I
25
HHSearch
98.02
62%
-107
- C1 -
2FI1
1
?
A:
[4-189]
M
K
Y
H
D
Y
I
W
D
L
G
G
T
L
L
D
N
Y
E
T
-
S
T
A
A
F
V
E
T
L
A
L
Y
G
---
I
T
Q
--
D
H
-
D
S
V
Y
-
Q
A
--------
L
K
-
V
--------
S
T
P
F
---------------
A
I
E
T
-----------------
F
-------
A
------
P
---
N
-------
L
---------------
E
---------
N
------
F
----
L
E
K
Y
K
---
E
----
N
-
E
-
A
R
-
E
---
L
E
H
P
I
L
-
F
E
G
V
S
D
L
L
E
D
I
S
N
Q
G
G
R
H
F
L
V
S
H
R
N
D
Q
V
-
L
--
E
I
L
E
-
K
T
S
I
A
A
Y
F
-
T
-
E
V
V
T
S
S
S
--
G
F
K
R
-
K
P
N
P
E
S
M
L
Y
L
R
E
K
Y
--
Q
I
----
S
S
G
L
V
I
G
D
R
P
I
D
I
E
A
G
Q
A
A
G
L
D
T
H
-
L
F
T
S
I
V
N
L
R
Q
V
L
D
-
1
PsiBlast_PDB
97.80
62%
-107
- C1 -
2FI1
1
?
A:
[4-189]
M
K
Y
H
D
Y
I
W
D
L
G
G
T
L
L
D
N
Y
E
T
-
S
T
A
A
F
V
E
T
L
A
L
Y
G
---
I
T
Q
--
D
H
-
D
S
V
Y
-
Q
A
--------
L
K
-
V
--------
S
T
P
F
---------------
A
I
E
T
-----------------
F
-------
A
------
P
---
N
-------
L
---------------
E
---------
N
------
F
----
L
E
K
Y
K
---
E
----
N
-
E
-
A
R
-
E
---
L
E
H
P
I
L
-
F
E
G
V
S
D
L
L
E
D
I
S
N
Q
G
G
R
H
F
L
V
S
H
R
N
D
Q
V
-
L
--
E
I
L
E
-
K
T
S
I
A
A
Y
F
-
T
-
E
V
V
T
S
S
S
--
G
F
K
R
-
K
P
N
P
E
S
M
L
Y
L
R
E
K
Y
--
Q
I
----
S
S
G
L
V
I
G
D
R
P
I
D
I
E
A
G
Q
A
A
G
L
D
T
H
-
L
F
T
S
I
V
N
L
R
Q
V
L
D
-
2
PsiBlast_PDB
75.52
33%
-101
- C1 -
2GO7
6
?
A:
[7-181]
-----
F
I
W
D
L
D
G
T
L
L
D
S
Y
E
A
-
I
L
S
G
I
E
E
T
F
A
Q
F
S
---
I
P
Y
--
D
K
-
E
K
V
R
-
E
F
--------
I
F
-
K
--------
Y
S
V
Q
---------------
D
L
L
V
-----------------
R
-------
V
------
A
---
E
-------
D
---------------
R
---------
N
------
L
D
V
E
V
L
N
Q
V
R
---
A
----
Q
-
S
L
A
E
-
K
---
N
A
Q
V
V
L
-
M
P
G
A
R
E
V
L
A
W
A
D
E
S
G
I
Q
Q
F
I
Y
T
H
K
G
N
N
A
-
F
--
T
I
L
K
-
D
L
G
V
E
S
Y
F
-
T
-
E
I
L
T
S
Q
S
--
G
F
V
R
-
K
P
S
P
E
A
A
T
Y
L
L
D
K
Y
--
Q
L
NS--
D
N
T
Y
Y
I
G
D
R
T
L
D
V
E
F
A
Q
N
S
G
I
Q
S
I
-
N
F
L
E
S
T
Y
E
G
N
H
R
I
-
31
HHSearch
73.61
34%
-80
- C1 -
2GO7
6
?
A:
[4-188]
--
K
T
A
F
I
W
D
L
D
G
T
L
L
D
S
Y
E
A
-
I
L
S
G
I
E
E
T
F
A
Q
F
S
---
I
P
Y
--
D
K
-
E
K
V
R
-
E
F
--------
I
F
K
Y
--------
S
V
Q
D
---------------
L
L
V
R
-----------------
V
-------
A
------
E
---
D
-------
R
---------------
N
---------
L
------
D
V
E
V
-
L
N
Q
V
R
---
A
----
Q
S
L
-
A
E
-
K
---
N
A
Q
V
V
L
-
M
P
G
A
R
E
V
L
A
W
A
D
E
S
G
I
Q
Q
F
I
Y
T
H
K
G
N
-
N
A
F
--
T
I
L
K
-
D
L
G
V
E
S
Y
F
-
T
-
E
I
L
T
S
Q
S
--
G
F
V
R
-
K
P
S
P
E
A
A
T
Y
L
L
D
K
Y
--
Q
L
NS--
D
N
T
Y
Y
I
G
D
R
T
L
D
V
E
F
A
Q
N
S
G
I
Q
S
I
-
N
F
L
E
S
T
Y
E
G
N
H
R
I
-
5
PsiBlast_PDB
66.42
22%
-59
- C1 -
4EX6
2
?
A:
[23-203]
------
I
L
D
L
D
G
T
L
A
D
T
P
A
A
-
I
A
T
I
T
A
E
V
L
A
A
M
G
---
T
A
V
--
S
R
-
G
A
I
L
-
S
T
--------
V
G
-
R
--------
P
L
P
A
---------------
S
L
A
G
-----------------
L
-------
L
GVPVED
P
---
R
-------
V
---------------
A
---------
E
------
A
----
T
E
E
Y
G
R
R
F
G
----
A
-
H
-
V
R
-
A
---
A
G
P
R
L
L
-
Y
P
G
V
L
E
G
L
D
R
L
S
A
A
G
F
R
L
A
M
A
T
S
K
V
E
K
A
-
A
--
R
A
I
A
-
E
L
T
G
L
D
T
R
-
L
-
T
V
I
A
G
D
D
--
S
V
E
R
G
K
P
H
P
D
M
A
L
H
V
A
R
G
L
--
G
I
PP--
E
R
C
V
V
I
G
D
G
V
P
D
A
E
M
G
R
A
A
G
M
T
V
I
-
G
V
S
Y
G
V
S
G
P
D
E
L
M
-
6
PsiBlast_PDB
66.37
22%
-59
- C1 -
4EX7
3
?
A:
[23-203]
------
I
L
D
L
D
G
T
L
A
D
T
P
A
A
-
I
A
T
I
T
A
E
V
L
A
A
M
G
---
T
A
V
--
S
R
-
G
A
I
L
-
S
T
--------
V
G
-
R
--------
P
L
P
A
---------------
S
L
A
G
-----------------
L
-------
L
GVPVED
P
---
R
-------
V
---------------
A
---------
E
------
A
----
T
E
E
Y
G
R
R
F
G
----
A
-
H
-
V
R
-
A
---
A
G
P
R
L
L
-
Y
P
G
V
L
E
G
L
D
R
L
S
A
A
G
F
R
L
A
M
A
T
S
K
V
E
K
A
-
A
--
R
A
I
A
-
E
L
T
G
L
D
T
R
-
L
-
T
V
I
A
G
D
D
--
S
V
E
R
G
K
P
H
P
D
M
A
L
H
V
A
R
G
L
--
G
I
PP--
E
R
C
V
V
I
G
D
G
V
P
D
A
E
M
G
R
A
A
G
M
T
V
I
-
G
V
S
Y
G
V
S
G
P
D
E
L
M
-
10
PsiBlast_PDB
64.64
24%
-59
- C1 -
3SD7
5
?
A:
[28-222]
-
N
Y
E
I
V
L
F
D
L
D
G
T
L
T
D
P
K
E
G
-
I
T
K
S
I
Q
Y
S
L
N
S
F
G
---
I
K
E
--
D
L
-
E
N
L
D
-
Q
F
--------
I
G
-
P
--------
P
L
H
D
---------------
T
F
K
E
-----------------
Y
YKFE
D
K
K
A
------
K
---
E
-------
A
---------------
V
---------
E
------
K
----
Y
R
E
Y
F
---
A
----
D
-
K
-
G
--
I
---
F
E
N
K
I
--
Y
E
N
M
K
E
I
L
E
M
L
Y
K
N
G
-
K
I
L
L
V
A
T
S
K
P
T
V
-
F
A
E
T
I
L
R
-
Y
F
D
I
D
R
Y
F
-
K
-
Y
I
A
G
S
N
L
--
D
G
T
R
-
V
N
K
N
E
V
I
Q
Y
V
L
D
L
C
--
N
V
KDK-
D
K
V
I
M
V
G
D
R
K
Y
D
I
I
G
A
K
K
I
G
I
D
S
I
G
V
L
Y
G
Y
G
S
F
E
E
I
S
E
-
41
HHSearch
63.01
19%
-52
- C1 -
1TE2
2
YNIC_ECOLI
A:
[7-198]
R
Q
I
L
A
A
I
F
D
M
D
G
L
L
I
D
S
E
P
L
-
W
D
R
A
E
L
D
V
M
A
S
L
G
---
V
D
I
--
S
R
R
N
E
L
P
-
D
T
--------
L
G
-
L
--------
R
I
D
M
---------------
V
V
D
L
-----------------
W
-------
Y
------
A
---
R
Q
P
W
N
GPS
R
---------------
Q
---------
E
------
V
----
V
E
R
V
I
---
A
----
R
-
A
-
I
S
L
V
---
E
E
T
R
P
L
-
L
P
G
V
R
E
A
V
A
L
C
K
E
Q
G
L
L
V
G
L
A
S
A
S
P
L
H
M
L
E
--
K
V
L
T
-
M
F
D
L
R
D
S
F
-
D
-
A
L
A
S
A
E
K
--
L
P
Y
S
-
K
P
H
P
Q
V
Y
L
D
C
A
A
K
L
--
G
V
DP--
L
T
C
V
A
L
E
D
S
V
N
G
M
I
A
S
K
A
A
R
M
R
S
I
-
V
V
P
A
P
E
A
Q
N
D
P
R
F
-
30
HHSearch
61.14
21%
-45
- C1 -
2HDO
2
?
A:
[2-186]
M
T
Y
Q
A
L
M
F
D
I
D
G
T
L
T
N
S
Q
P
A
-
Y
T
T
V
M
R
E
V
L
A
T
Y
G
---
K
P
F
--
S
P
-
A
Q
A
Q
-
K
T
--------
F
P
-
M
--------
A
A
E
Q
---------------
A
M
T
E
-----------------
L
-------
G
------
I
---
A
ASE----
F
---------------
D
---------
H
------
F
----
Q
A
Q
Y
E
---
D
----
V
-
M
-
A
S
-
H
---
Y
D
Q
I
E
L
-
Y
P
G
I
T
S
L
F
E
Q
L
P
S
-
E
L
R
L
G
I
V
T
S
Q
R
R
N
E
L
E
--
S
G
M
R
-
S
Y
P
F
M
M
R
M
-
A
-
V
T
I
S
A
D
D
--
T
P
K
R
-
K
P
D
P
L
P
L
L
T
A
L
E
K
V
--
N
V
AP--
Q
N
A
L
F
I
G
D
S
V
S
D
E
Q
T
A
Q
A
A
N
V
D
F
G
-
L
A
V
W
G
M
D
P
N
A
D
H
Q
-
20
PsiBlast_PDB
61.01
26%
-74
- C1 -
3S6J
1
?
A:
[9-172]
-----
F
I
F
D
L
D
G
T
L
T
D
S
V
Y
Q
-
N
V
A
A
W
K
E
A
L
D
A
E
N
---
I
P
L
--
A
M
-
W
R
I
H
-
R
K
IGMS
G
G
L
M
L
K
-
S
--------
L
S
R
E
------------------------------------
I
-------
T
------
D
---
E
-------
Q
---------------
A
---------
E
------
R
----
L
S
E
K
H
---
A
----
Q
-
A
-
Y
E
-
R
---
L
Q
H
Q
I
I
A
L
P
G
A
V
E
L
L
E
T
L
D
K
E
N
L
K
W
C
I
A
T
S
G
G
I
D
T
-
A
--
T
I
N
L
-
K
A
L
K
L
D
I
N
K
I
-
N
I
V
T
R
D
D
--
V
S
Y
G
-
K
P
D
P
D
L
F
L
A
A
A
K
K
I
GA
P
I
----
D
E
C
L
V
I
G
D
A
I
W
D
M
L
A
A
R
R
C
K
A
T
G
V
-
G
L
L
S
G
G
Y
D
I
G
E
L
E
-
11
PsiBlast_PDB
60.87
22%
-46
- C1 -
2HDO
2
?
A:
[3-177]
-
T
Y
Q
A
L
M
F
D
I
D
G
T
L
T
N
S
Q
P
A
-
Y
T
T
V
M
R
E
V
L
A
T
Y
G
K
P
F
S
P
A
--
Q
A
-
Q
K
T
F
-
P
M
--------
A
A
-
E
--------
Q
A
M
T
---------------
E
L
G
I
-----------------
A
-------
A
------
S
---
E
-------
F
---------------
D
---------
H
------
F
----
Q
A
Q
Y
E
---
D
----
V
-
M
-
A
S
-
H
---
Y
D
Q
I
E
L
-
Y
P
G
I
T
S
L
F
E
Q
L
P
S
E
L
R
L
G
I
V
T
S
Q
R
R
N
E
L
-
E
--
S
G
M
R
-
S
Y
P
F
M
M
R
M
-
A
-
V
T
I
S
A
D
D
--
T
P
K
R
-
K
P
D
P
L
P
L
L
T
A
L
E
K
V
--
N
V
AP--
Q
N
A
L
F
I
G
D
S
V
S
D
E
Q
T
A
Q
A
A
N
V
D
F
G
-
L
A
V
W
G
M
D
P
N
A
D
H
Q
-
29
HHSearch
60.20
21%
-63
- C1 -
3SD7
5
?
A:
[27-217]
K
N
Y
E
I
V
L
F
D
L
D
G
T
L
T
D
P
K
E
G
-
I
T
K
S
I
Q
Y
S
L
N
S
F
G
---
I
K
E
--
D
L
-
E
N
L
D
-
Q
F
--------
I
G
-
P
--------
P
L
H
D
---------------
T
F
K
E
-----------------
Y
-------
Y
------
K
---
F
-------
E
---------------
D
---------
K
------
K
A
K
E
A
V
E
K
Y
R
---
E
----
Y
-
F
-
A
D
K
G
---
I
F
E
N
K
I
-
Y
E
N
M
K
E
I
L
E
M
L
Y
K
N
G
K
I
L
L
V
A
T
S
K
P
T
V
F
A
E
--
T
I
L
R
-
Y
F
D
I
D
R
Y
F
-
K
-
Y
I
A
G
S
N
L
--
D
G
T
R
-
V
N
K
N
E
V
I
Q
Y
V
L
D
L
C
--
N
V
KDK-
D
K
V
I
M
V
G
D
R
K
Y
D
I
I
G
A
K
K
I
G
I
D
S
I
-
G
V
L
Y
G
Y
G
S
F
E
E
I
S
-
42
HHSearch
60.14
20%
-55
- C1 -
3L5K
6
HDHD1_HUMAN
A:
[28-222]
Q
P
V
T
H
L
I
F
D
M
D
G
L
L
L
D
T
E
R
L
-
Y
S
V
V
F
Q
E
I
C
N
R
Y
D
---
K
K
Y
--
S
W
-
D
V
K
S
-
L
V
--------
M
G
-
K
--------
K
A
L
E
---------------
A
A
Q
I
-----------------
I
-------
I
------
D
---
V
-------
L
---------------
Q
---------
L
PMS
K
E
E
L
----
V
E
E
S
Q
---
T
----
K
-
L
-
K
E
-
V
---
F
P
T
A
A
L
-
M
P
G
A
E
K
L
I
I
H
L
R
K
H
G
I
P
F
A
L
A
T
S
S
R
S
A
S
F
D
--
M
K
T
S
R
H
K
E
F
F
S
L
F
-
S
-
H
I
V
L
G
D
D
PE
V
Q
H
G
-
K
P
D
P
D
I
F
L
A
C
A
K
R
F
--
S
P
PPAM
E
K
C
L
V
F
E
D
A
P
N
G
V
E
A
A
L
A
A
G
M
Q
V
V
-
M
V
P
D
G
N
L
S
R
D
L
T
T
-
33
HHSearch
59.26
19%
-66
- C1 -
3KBB
7
P1254_THEMA
A:
[1-188]
--
M
E
A
V
I
F
D
M
D
G
V
L
M
D
T
E
P
L
-
Y
F
E
A
Y
R
R
V
A
E
S
Y
G
---
K
P
Y
--
T
E
-
D
L
H
R
-
R
I
--------
M
G
-
V
--------
P
E
R
E
---------------
G
L
P
I
-----------------
L
-------
M
------
E
---
A
-------
L
---------------
E
---------
I
K
D
----
S
----
L
E
N
F
K
---
K
R
V
H
E
E
-
K
-
K
R
V
F
---
S
E
L
L
K
E
-
N
P
G
V
R
E
A
L
E
F
V
K
S
K
R
I
K
L
A
L
A
T
S
T
P
Q
R
E
A
L
--
E
R
L
R
-
R
L
D
L
E
K
Y
F
-
D
-
V
M
V
F
G
D
Q
--
V
K
N
G
-
K
P
D
P
E
I
Y
L
L
V
L
E
R
L
--
N
V
VP--
E
K
V
V
V
F
E
D
S
K
S
G
V
E
A
A
K
S
A
G
I
E
R
I
Y
G
V
V
H
S
L
N
D
G
K
A
L
L
-
40
HHSearch
59.19
19%
-40
* C1 *
3IRU
1
?
A:
[12-217]
G
P
V
E
A
L
I
L
D
W
A
G
T
T
I
D
F
G
S
L
A
P
V
Y
A
F
M
E
L
F
K
Q
E
G
---
I
E
V
--
T
Q
-
A
E
A
R
-
E
P
--------
M
G
-
T
--------
E
K
S
E
---------------
H
I
R
R
-----------------
M
-------
L
------
G
---
N
-------
S
R
I
A
N
A
W
L
S
I
KGQASN
E
E
D
I
K
-----
R
------
L
----
Y
D
L
F
A
---
P
----
I
-
Q
-
T
R
I
V
---
A
Q
R
S
Q
L
-
I
P
G
W
K
E
V
F
D
K
L
I
A
Q
G
I
K
V
G
G
N
T
G
Y
G
P
G
M
M
A
--
P
A
L
I
-
A
A
K
E
Q
G
Y
T
-
P
A
S
T
V
F
A
T
D
--
V
V
R
G
-
R
P
F
P
D
M
A
L
K
V
A
L
E
L
--
E
V
GHV-
N
G
C
I
K
V
D
D
T
L
P
G
I
E
E
G
L
R
A
G
M
W
T
V
-
G
V
S
C
S
G
N
E
V
G
L
D
R
-
7
PsiBlast_PDB
58.40
22%
-58
- C1 -
2HI0
9
?
A:
[4-209]
--
Y
K
A
A
I
F
D
M
D
G
T
I
L
D
T
S
A
D
-
L
T
S
A
L
N
Y
A
F
E
Q
T
G
---
H
R
----
H
-
D
F
T
V
-
E
D
--------
I
K
-
N
F
FGSG
V
V
V
A
V
T
R
---------------
A
L
A
Y
E
A
GSSRESLVAFGTKDE
Q
-------
I
------
P
---
E
-------
A
---------------
V
T
Q
T
E
V
N
R
V
L
E
------
V
----
F
K
P
Y
Y
---
A
----
D
-
H
-
C
Q
-
I
---
K
T
G
P
---
F
P
G
I
L
D
L
M
K
N
L
R
Q
K
G
V
K
L
A
V
V
S
N
K
P
N
E
A
-
V
--
Q
V
L
V
-
E
E
L
F
P
G
S
F
-
D
-
F
A
L
G
E
K
S
--
G
I
R
R
-
K
P
A
P
D
M
T
S
E
C
V
K
V
L
--
G
V
PR--
D
K
C
V
Y
I
G
D
S
E
I
D
I
Q
T
A
R
N
S
E
M
D
E
I
-
A
V
N
W
G
F
R
S
V
P
F
L
Q
-
28
HHSearch
57.76
19%
-59
- C1 -
3MC1
3
?
A:
[2-192]
S
L
Y
N
Y
V
L
F
D
L
D
G
T
L
T
D
S
A
E
G
-
I
T
K
S
V
K
Y
S
L
N
K
F
D
---
I
Q
V
--
E
D
L
S
S
L
N
-
K
F
--------
V
G
-
P
--------
P
L
K
T
---------------
S
F
M
E
-----------------
Y
-------
Y
------
N
---
F
-------
D
---------------
E
---------
E
T
A
T
V
--
A
----
I
D
Y
Y
R
---
D
----
Y
-
F
-
K
A
K
G
---
M
F
E
N
K
V
-
Y
D
G
I
E
A
L
L
S
S
L
K
D
Y
G
F
H
L
V
V
A
T
S
K
P
T
V
F
S
K
--
Q
I
L
E
-
H
F
K
L
A
F
Y
F
-
D
-
A
I
V
G
S
S
L
--
D
G
K
L
-
S
T
K
E
D
V
I
R
Y
A
M
E
S
L
--
N
I
KS--
D
D
A
I
M
I
G
D
R
E
Y
D
V
I
G
A
L
K
N
N
L
P
S
I
-
G
V
T
Y
G
F
G
S
Y
E
E
L
K
-
36
HHSearch
57.43
19%
-57
- C1 -
2WF7
3
PGMB_LACLA
A:
[1-194]
-
M
F
K
A
V
L
F
D
L
D
G
V
I
T
D
T
A
E
Y
-
H
F
R
A
W
K
A
L
A
E
E
I
G
---
I
N
G
--
V
D
-
R
Q
F
N
E
Q
L
--------
K
G
-
V
--------
S
R
E
D
---------------
S
L
Q
K
-----------------
I
-------
L
------
D
---
L
-------
A
---------------
D
K
K
V
S
A
E
E
F
K
E
------
L
----
A
K
R
K
N
---
D
----
N
-
Y
-
V
K
-
M
I
Q
D
V
S
P
A
D
V
-
Y
P
G
I
L
Q
L
L
K
D
L
R
S
N
K
I
K
I
A
L
A
S
A
S
K
N
-
G
-
P
--
F
L
L
E
-
R
M
N
L
T
G
Y
F
-
D
-
A
I
A
D
P
A
E
--
V
A
A
S
-
K
P
A
P
D
I
F
I
A
A
A
H
A
V
--
G
V
AP--
S
E
S
I
G
L
E
D
S
Q
A
G
I
Q
A
I
K
D
S
G
A
L
P
I
-
G
V
G
R
P
E
D
L
G
D
D
I
V
-
45
HHSearch
57.32
22%
-38
- C1 -
2HI0
9
?
A:
[2-214]
M
K
Y
K
A
A
I
F
D
M
D
G
T
I
L
D
T
S
A
D
-
L
T
S
A
L
N
Y
A
F
E
Q
T
G
---
H
R
H
DF
T
V
-
E
D
I
K
-
N
F
--------
F
G
-
S
--------
G
V
V
V
A
V
T
R
A
L
A
Y
E
A
GSSRE
S
L
V
A
-----------------
F
-------
G
------
T
KDE
Q
-------
I
---------------
P
EAVT
Q
T
E
V
N
R
------
V
----
L
E
V
F
K
---
P
----
Y
-
Y
-
A
D
-
H
C--
Q
I
K
T
G
P
-
F
P
G
I
L
D
L
M
K
N
L
R
Q
K
G
V
K
L
A
V
V
S
N
K
P
N
E
A
V
Q
--
V
L
V
E
-
E
L
F
-
P
G
S
F
-
D
-
F
A
L
G
E
K
S
--
G
I
R
R
-
K
P
A
P
D
M
T
S
E
C
V
K
V
L
--
G
V
PR--
D
K
C
V
Y
I
G
D
S
E
I
D
I
Q
T
A
R
N
S
E
M
D
E
I
-
A
V
N
W
G
F
R
S
V
P
F
L
Q
-