@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0605: (2015-12-02 )
MIKGLLVMDVDSTLIMEEAIDLLAIEAGVGKQVAALTDAAMRGELDFEEALKKRVALLKGLPVTILTDILSSIHFTPGAYELIKECHKRQMKVGLVSGGFHETIDILAKQLQVDYVKANRLGVKGGFLTGEVEGEIVTKEVKKIKLKEWASENHLDLSQTIAMGDGANDLPMIKSAGVGIAFCAKPIVREEAAYQINEKNLLKVFDIIDANEN
Atome Classification :
(23 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30........40........50........60........70.--........80........90........100.......110..--.....120..-.....130.-......140----.......150.......160.......170.......180....---.---..190.......200.......210.---------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MI
K
G
L
L
V
M
DVD
S
T
L
I
M
E
E
A
I
D
L
L
A
IEAGVG
K
Q
V
A
A
L
T
D
A
A
MRGEL
D
F
E
E
A
L
K
K
R
V
A
L
LKGL
P
V
T
I
L
T
D
I
L
-
S
--SIHFTP
G
A
Y
E
L
I
K
E
C
H
K
R
Q
M
K
V
G
L
VSGG
F
H
E
T
I
D
I
L
A
K
Q
L
Q
V
D
--
Y
V
KANRLGVK-G
G
F
L
TGEVE-G
E
I
V
T
K
E
V
K
----
K
I
K
L
K
E
WASENHL
D
L
S
Q
TIAMGDGANDLPMIKSAGV
G
I
A
F
CAKP---I---VRE
E
A
A
Y
QIN
E
K
N
L
L
K
V
F
D
IIDANEN---------
66
Fugue
94.86
43%
-102
* C2 *
3P96
3
SERB_MYCA1
A:
[9-404]
PK
V
S
V
L
I
T
V
T
G
VDQPG
V
T
A
T
L
F
E
V
L
S
R
H
GVELL
N
V
E
Q
V
V
I
RH
R
L
T
L
G
V
L
V
C
C
P
A
D
V
A
D
GP
A
L
R
H
D
V
E
A
A
I
R
K
V
G
L
D
V
S
I
E
R
S
DDVPI
I
R
E
P
ST
H
T
I
F
V
L
G
RPIT
A
A
A
F
G
A
V
A
R
E
V
A
A
L
GVNID
L
I
R
G
VSDYP
V
I
G
L
E
L
R
V
S
V
P
P
GA
D
E
A
L
R
T
A
L
N
R
V
S
S
E
E
H
V
D
V
A
V
E
D
YTLER
R
A
K
R
L
I
V
F
D
V
D
S
T
L
V
Q
G
E
V
I
E
M
L
A
A
K
A
G
A
E
G
Q
V
A
A
I
T
D
A
A
M
R
G
E
L
D
F
A
Q
S
L
Q
Q
R
V
A
T
L
A
G
L
P
A
T
V
I
D
E
V
A
-
G
--
Q
L
E
L
M
P
G
A
R
T
T
L
R
T
L
R
R
L
G
Y
A
C
G
V
V
S
G
G
F
R
R
I
I
E
P
L
A
E
E
L
M
L
D
--
Y
V
A
A
N
E
L
E
I
V
-
D
G
T
L
T
G
R
V
V
-
G
P
I
I
D
R
A
G
K
----
A
T
A
L
R
E
F
A
Q
R
A
G
V
P
M
A
Q
T
V
A
V
G
D
G
A
N
D
I
D
M
L
A
A
A
G
L
G
I
A
F
N
A
K
P
---
A
---
L
R
E
V
A
D
A
S
L
S
H
P
Y
L
D
T
V
L
F
L
L
G
V
T
R
G
E
I
E
A
A
D
A
I
D
78
HHSearch
93.31
44%
-103
- C2 -
3P96
3
SERB_MYCA1
A:
[184-393]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
R
L
I
V
F
D
V
D
S
T
L
V
Q
G
E
V
I
E
M
L
A
A
K
A
G
A
E
G
Q
V
A
A
I
T
D
A
A
M
R
G
E
L
D
F
A
Q
S
L
Q
Q
R
V
A
T
L
A
G
L
P
A
T
V
I
D
E
V
A
-
G
--
Q
L
E
L
M
P
G
A
R
T
T
L
R
T
L
R
R
L
G
Y
A
C
G
V
V
S
G
G
F
R
R
I
I
E
P
L
A
E
E
L
M
L
D
--
Y
V
A
A
N
E
L
E
I
V
-
D
G
T
L
T
G
R
V
V
-
G
P
I
I
D
R
A
G
K
----
A
T
A
L
R
E
F
A
Q
R
A
G
V
P
M
A
Q
T
V
A
V
G
D
G
A
N
D
I
D
M
L
A
A
A
G
L
G
I
A
F
N
A
K
P
---
A
---
L
R
E
V
A
D
A
S
L
S
H
P
Y
L
D
T
V
L
F
L
L
G
V
T
R
G
---------
1
PsiBlast_PDB
92.46
45%
-100
- C2 -
3P96
3
SERB_MYCA1
A:
[185-387]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
L
I
V
F
D
V
D
S
T
L
V
Q
G
E
V
I
E
M
L
A
A
K
A
G
A
E
G
Q
V
A
A
I
T
D
A
A
M
R
G
E
L
D
F
A
Q
S
L
Q
Q
R
V
A
T
L
A
G
L
P
A
T
V
I
D
E
V
A
-
G
--
Q
L
E
L
M
P
G
A
R
T
T
L
R
T
L
R
R
L
G
Y
A
C
G
V
V
S
G
G
F
R
R
I
I
E
P
L
A
E
E
L
M
L
D
--
Y
V
A
A
N
E
L
E
I
V
-
D
G
T
L
T
G
R
V
V
-
G
P
I
I
D
R
A
G
K
----
A
T
A
L
R
E
F
A
Q
R
A
G
V
P
M
A
Q
T
V
A
V
G
D
G
A
N
D
I
D
M
L
A
A
A
G
L
G
I
A
F
N
A
K
P
---
A
---
L
R
E
V
A
D
A
S
L
S
H
P
Y
L
D
T
V
L
F
L
L
G
V
T
R
G
---------
7
PsiBlast_PDB
91.77
42%
-106
- C2 -
3N28
2
?
A:
[108-314]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
I
V
L
D
M
D
S
T
A
I
Q
I
E
C
I
D
E
I
A
K
L
A
G
V
G
E
E
V
A
E
V
T
E
R
A
M
Q
G
E
L
D
F
E
Q
S
L
R
L
R
V
S
K
L
K
D
A
P
E
Q
I
L
S
Q
V
R
-
E
--
T
L
P
L
M
P
E
L
P
E
L
V
A
T
L
H
A
F
G
W
K
V
A
I
A
S
G
G
F
T
Y
F
S
D
Y
L
K
E
Q
L
S
L
D
--
Y
A
Q
S
N
T
L
E
I
V
-
S
G
K
L
T
G
Q
V
L
-
G
E
V
V
S
A
Q
T
K
----
A
D
I
L
L
T
L
A
Q
Q
Y
D
V
E
I
H
N
T
V
A
V
G
D
G
A
N
D
L
V
M
M
A
A
A
G
L
G
V
A
Y
H
A
K
P
---
K
---
V
E
A
K
A
Q
T
A
V
R
F
A
G
L
G
G
V
V
C
I
L
S
A
A
L
V
---------
65
Fugue
91.38
40%
-99
- C2 -
3N28
6
?
A:
[3-325]
------------------------------------------------------------------------LDALTTL
P
I
K
K
H
T
A
L
L
N
R
F
PETRFVTQLAKKRAS
W
I
V
F
G
HYLT
P
A
Q
F
E
D
M
D
F
F
T
N
R
F
N
A
I
L
D
M
W
K
V
GR
Y
E
V
A
LM
D
G
E
L
T
S
E
H
E
T
I
L
K
A
L
E
L
D
Y
A
R
IQDVPDL
T
K
P
G
L
I
V
L
D
M
D
S
T
A
I
Q
I
E
C
I
D
E
I
A
K
L
A
G
V
G
E
E
V
A
E
V
T
E
R
A
M
Q
G
E
L
D
F
E
Q
S
L
R
L
R
V
S
K
L
K
D
A
P
E
Q
I
L
S
Q
V
R
-
E
--
T
L
P
L
M
P
E
L
P
E
L
V
A
T
L
H
A
F
G
W
K
V
A
I
A
S
G
G
F
T
Y
F
S
D
Y
L
K
E
Q
L
S
L
D
--
Y
A
Q
S
N
T
L
E
I
V
-
S
G
K
L
T
G
Q
V
L
-
G
E
V
V
S
A
Q
T
K
----
A
D
I
L
L
T
L
A
Q
Q
Y
D
V
E
I
H
N
T
V
A
V
G
D
G
A
N
D
L
V
M
M
A
A
A
G
L
G
V
A
Y
H
A
K
P
---
K
---
V
E
A
K
A
Q
T
A
V
R
F
A
G
L
G
G
V
V
C
I
L
S
A
A
L
V
A
Q
QKLSWK-
75
HHSearch
91.23
41%
-101
- C2 -
3N28
2
?
A:
[105-315]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
P
G
L
I
V
L
D
M
D
S
T
A
I
Q
I
E
C
I
D
E
I
A
K
L
A
G
V
G
E
E
V
A
E
V
T
E
R
A
M
Q
G
E
L
D
F
E
Q
S
L
R
L
R
V
S
K
L
K
D
A
P
E
Q
I
L
S
Q
V
R
-
E
--
T
L
P
L
M
P
E
L
P
E
L
V
A
T
L
H
A
F
G
W
K
V
A
I
A
S
G
G
F
T
Y
F
S
D
Y
L
K
E
Q
L
S
L
D
--
Y
A
Q
S
N
T
L
E
I
V
-
S
G
K
L
T
G
Q
V
L
-
G
E
V
V
S
A
Q
T
K
----
A
D
I
L
L
T
L
A
Q
Q
Y
D
V
E
I
H
N
T
V
A
V
G
D
G
A
N
D
L
V
M
M
A
A
A
G
L
G
V
A
Y
H
A
K
P
---
K
---
V
E
A
K
A
Q
T
A
V
R
F
A
G
L
G
G
V
V
C
I
L
S
A
A
L
V
---------
3
PsiBlast_PDB
89.06
44%
-101
- C2 -
1L7M
4
SERB_METJA
A:
[5-210]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
L
I
L
F
D
F
D
S
T
L
V
N
N
E
T
I
D
E
I
A
R
E
A
G
V
E
E
E
V
K
K
I
T
K
E
A
M
E
G
K
L
N
F
E
Q
S
L
R
K
R
V
S
L
L
K
D
L
P
I
E
K
V
E
K
A
I
-
K
--
R
I
T
P
T
E
G
A
E
E
T
I
K
E
L
K
N
R
G
Y
V
V
A
V
V
S
G
G
F
D
I
A
V
N
K
I
K
E
K
L
G
L
D
--
Y
A
F
A
N
R
L
I
V
K
-
D
G
K
L
T
G
D
V
E
-
G
E
V
L
K
E
N
A
K
----
G
E
I
L
E
K
I
A
K
I
E
G
I
N
L
E
D
T
V
A
V
G
D
G
A
N
D
I
S
M
F
K
K
A
G
L
K
I
A
F
C
A
K
P
---
I
---
L
K
E
K
A
D
I
C
I
E
K
R
D
L
R
E
I
L
K
Y
I
K
-------------
21
PsiBlast_CBE
88.73
45%
-98
- C2 -
1F5S
4
SERB_METJA
B:
[5-210]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
L
I
L
F
D
F
D
S
T
L
V
N
N
E
T
I
D
E
I
A
R
E
A
G
V
E
E
E
V
K
K
I
T
K
E
A
M
E
G
K
L
N
F
E
Q
S
L
R
K
R
V
S
L
L
K
D
L
P
I
E
K
V
E
K
A
I
-
K
--
R
I
T
P
T
E
G
A
E
E
T
I
K
E
L
K
N
R
G
Y
V
V
A
V
V
S
G
G
F
D
I
A
V
N
K
I
K
E
K
L
G
L
D
--
Y
A
F
A
N
R
L
I
V
K
-
D
G
K
L
T
G
D
V
E
-
G
E
V
L
K
E
N
A
K
----
G
E
I
L
E
K
I
A
K
I
E
G
I
N
L
E
D
T
V
A
V
G
D
G
A
N
D
I
S
M
F
K
K
A
G
L
K
I
A
F
C
A
K
P
---
I
---
L
K
E
K
A
D
I
C
I
E
K
R
D
L
R
E
I
L
K
Y
I
K
-------------
4
PsiBlast_PDB
88.72
44%
-100
- C2 -
1L7N
3
SERB_METJA
A:
[5-210]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
L
I
L
F
D
F
D
S
T
L
V
N
N
E
T
I
D
E
I
A
R
E
A
G
V
E
E
E
V
K
K
I
T
K
E
A
M
E
G
K
L
N
F
E
Q
S
L
R
K
R
V
S
L
L
K
D
L
P
I
E
K
V
E
K
A
I
-
K
--
R
I
T
P
T
E
G
A
E
E
T
I
K
E
L
K
N
R
G
Y
V
V
A
V
V
S
G
G
F
D
I
A
V
N
K
I
K
E
K
L
G
L
D
--
Y
A
F
A
N
R
L
I
V
K
-
D
G
K
L
T
G
D
V
E
-
G
E
V
L
K
E
N
A
K
----
G
E
I
L
E
K
I
A
K
I
E
G
I
N
L
E
D
T
V
A
V
G
D
G
A
N
D
I
S
M
F
K
K
A
G
L
K
I
A
F
C
A
K
P
---
I
---
L
K
E
K
A
D
I
C
I
E
K
R
D
L
R
E
I
L
K
Y
I
K
-------------
67
Fugue
88.18
44%
-101
- C2 -
1F5S
3
SERB_METJA
A:
[2-211]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------E
K
K
K
K
L
I
L
F
D
F
D
S
T
L
V
N
N
E
T
I
D
E
I
A
R
E
A
G
V
E
E
E
V
K
K
I
T
K
E
A
M
E
G
K
L
N
F
E
Q
S
L
R
K
R
V
S
L
L
K
D
L
P
I
E
K
V
E
K
A
I
-
K
--
R
I
T
P
T
E
G
A
E
E
T
I
K
E
L
K
N
R
G
Y
V
V
A
V
V
S
G
G
F
D
I
A
V
N
K
I
K
E
K
L
G
L
D
--
Y
A
F
A
N
R
L
I
V
K
-
D
G
K
L
T
G
D
V
E
-
G
E
V
L
K
E
N
A
K
----
G
E
I
L
E
K
I
A
K
I
E
G
I
N
L
E
D
T
V
A
V
G
D
G
A
N
D
I
S
M
F
K
K
A
G
L
K
I
A
F
C
A
K
P
---
I
---
L
K
E
K
A
D
I
C
I
E
K
R
D
L
R
E
I
L
K
Y
I
K
-------------
6
PsiBlast_PDB
88.07
43%
-103
- C2 -
1L7P
1
SERB_METJA
A:
[5-210]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
L
I
L
F
N
F
D
S
T
L
V
N
N
E
T
I
D
E
I
A
R
E
A
G
V
E
E
E
V
K
K
I
T
K
E
A
M
E
G
K
L
N
F
E
Q
S
L
R
K
R
V
S
L
L
K
D
L
P
I
E
K
V
E
K
A
I
-
K
--
R
I
T
P
T
E
G
A
E
E
T
I
K
E
L
K
N
R
G
Y
V
V
A
V
V
S
G
G
F
D
I
A
V
N
K
I
K
E
K
L
G
L
D
--
Y
A
F
A
N
R
L
I
V
K
-
D
G
K
L
T
G
D
V
E
-
G
E
V
L
K
E
N
A
K
----
G
E
I
L
E
K
I
A
K
I
E
G
I
N
L
E
D
T
V
A
V
G
D
G
A
N
D
I
S
M
F
K
K
A
G
L
K
I
A
F
C
A
K
P
---
I
---
L
K
E
K
A
D
I
C
I
E
K
R
D
L
R
E
I
L
K
Y
I
K
S
------------
2
PsiBlast_PDB
88.05
45%
-102
- C2 -
1F5S
2
SERB_METJA
A:
[5-210]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
L
I
L
F
D
F
D
S
T
L
V
N
N
E
T
I
D
E
I
A
R
E
A
G
V
E
E
E
V
K
K
I
T
K
E
A
M
E
G
K
L
N
F
E
Q
S
L
R
K
R
V
S
L
L
K
D
L
P
I
E
K
V
E
K
A
I
-
K
--
R
I
T
P
T
E
G
A
E
E
T
I
K
E
L
K
N
R
G
Y
V
V
A
V
V
S
G
G
F
D
I
A
V
N
K
I
K
E
K
L
G
L
D
--
Y
A
F
A
N
R
L
I
V
K
-
D
G
K
L
T
G
D
V
E
-
G
E
V
L
K
E
N
A
K
----
G
E
I
L
E
K
I
A
K
I
E
G
I
N
L
E
D
T
V
A
V
G
D
G
A
N
D
I
S
M
F
K
K
A
G
L
K
I
A
F
C
A
K
P
---
I
---
L
K
E
K
A
D
I
C
I
E
K
R
D
L
R
E
I
L
K
Y
I
K
-------------
76
HHSearch
87.74
44%
-97
- C2 -
1L7M
4
SERB_METJA
A:
[3-209]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
K
K
L
I
L
F
D
F
D
S
T
L
V
N
N
E
T
I
D
E
I
A
R
E
A
G
V
E
E
E
V
K
K
I
T
K
E
A
M
E
G
K
L
N
F
E
Q
S
L
R
K
R
V
S
L
L
K
D
L
P
I
E
K
V
E
K
A
I
-
K
--
R
I
T
P
T
E
G
A
E
E
T
I
K
E
L
K
N
R
G
Y
V
V
A
V
V
S
G
G
F
D
I
A
V
N
K
I
K
E
K
L
G
L
D
--
Y
A
F
A
N
R
L
I
V
K
-
D
G
K
L
T
G
D
V
E
-
G
E
V
L
K
E
N
A
K
----
G
E
I
L
E
K
I
A
K
I
E
G
I
N
L
E
D
T
V
A
V
G
D
G
A
N
D
I
S
M
F
K
K
A
G
L
K
I
A
F
C
A
K
P
---
I
---
L
K
E
K
A
D
I
C
I
E
K
R
D
L
R
E
I
L
K
Y
I
K
-------------
5
PsiBlast_PDB
87.17
43%
-106
- C2 -
1L7O
3
SERB_METJA
A:
[5-210]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
L
I
L
F
N
F
D
S
T
L
V
N
N
E
T
I
D
E
I
A
R
E
A
G
V
E
E
E
V
K
K
I
T
--------
N
F
E
Q
S
L
R
K
R
V
S
L
L
K
D
L
P
I
E
K
V
E
K
A
I
-
K
--
R
I
T
P
T
E
G
A
E
E
T
I
K
E
L
K
N
R
G
Y
V
V
A
V
V
S
G
G
F
D
I
A
V
N
K
I
K
E
K
L
G
L
D
--
Y
A
F
A
N
R
L
I
V
K
-
D
G
K
L
T
G
D
V
E
-
G
E
V
L
K
E
N
A
K
----
G
E
I
L
E
K
I
A
K
I
E
G
I
N
L
E
D
T
V
A
V
G
D
G
A
N
D
I
S
M
F
K
K
A
G
L
K
I
A
F
C
A
K
P
---
I
---
L
K
E
K
A
D
I
C
I
E
K
R
D
L
R
E
I
L
K
Y
I
K
-------------
68
Fugue
84.93
33%
-111
- C2 -
4EZE
2
?
A:
[21-317]
-----------------------------------------------------------------------------------------------QS
M
S
I
I
Y
F
I
T
TQD
I
D
T
F
Q
K
K
L
Q
E
T
L
FF
P
L
L
F
D
K
R
Y
AALIN
T
A
Y
L
K
L
T
L
P
AECLT
P
E
F
Y
R
Y
L
R
E
L
S
L
Q
W
Q
F
D
F
F
IKPQPL
P
A
N
G
I
I
A
F
D
M
D
S
T
F
I
A
E
E
G
V
D
E
I
A
R
E
L
G
M
S
T
Q
I
T
A
I
T
Q
Q
A
M
E
G
K
L
D
F
N
A
S
F
T
R
R
I
G
M
L
K
G
T
P
K
A
V
L
N
A
V
C
-
D
--
R
M
T
L
S
P
G
L
L
T
I
L
P
V
I
K
A
K
G
F
K
T
A
I
I
S
G
G
L
D
I
F
T
Q
R
L
K
A
R
Y
Q
L
D
--
Y
A
F
S
N
T
V
E
I
R
-
D
N
V
L
T
D
N
I
T
-
L
P
I
M
N
A
A
N
K
----
K
Q
T
L
V
D
L
A
A
R
L
N
I
A
T
E
N
I
I
A
C
G
D
G
A
N
D
L
P
M
L
E
H
A
G
T
G
I
A
W
K
A
K
P
---
V
---
V
R
E
K
I
H
H
Q
I
N
Y
H
G
F
E
L
L
L
F
L
I
E
D
E
L
----------
22
PsiBlast_CBE
83.86
35%
-102
- C2 -
4EZE
2
?
B:
[108-302]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
G
I
I
A
F
D
M
D
S
T
F
I
A
E
E
G
V
D
E
I
A
R
E
L
G
M
S
T
Q
I
T
A
I
T
Q
Q
A
M
E
G
K
L
D
F
N
A
S
F
T
R
R
I
G
M
L
K
G
T
P
K
A
V
L
N
A
V
C
-
D
--
R
M
T
L
S
P
G
L
L
T
I
L
P
V
I
K
A
K
G
F
K
T
A
I
I
S
G
G
L
D
I
F
T
Q
R
L
K
A
R
Y
Q
L
D
--
Y
A
F
S
N
T
V
E
I
R
-
D
N
V
L
T
D
N
I
T
-
L
P
I
M
N
A
A
N
K
----
K
Q
T
L
V
D
L
A
A
R
L
N
I
A
T
E
N
I
I
A
C
G
D
G
A
N
D
L
P
M
L
E
H
A
G
T
G
I
A
W
K
A
K
P
---
V
---
V
R
E
K
I
H
H
Q
I
N
Y
H
G
F
E
L
L
L
F
L
I
E
D
E
L
----------
8
PsiBlast_PDB
81.09
35%
-103
- C2 -
4EZE
2
?
A:
[108-302]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
G
I
I
A
F
D
M
D
S
T
F
I
A
E
E
G
V
D
E
I
A
R
E
L
G
M
S
T
Q
I
T
A
I
T
Q
Q
A
M
E
G
K
L
D
F
N
A
S
F
T
R
R
I
G
M
L
K
G
T
P
K
A
V
L
N
A
V
C
-
D
--
R
M
T
L
S
P
G
L
L
T
I
L
P
V
I
K
A
K
G
F
K
T
A
I
I
S
G
G
L
D
I
F
T
Q
R
L
K
A
R
Y
Q
L
D
--
Y
A
F
S
N
T
V
E
I
R
-
D
N
V
L
T
D
N
I
T
-
L
P
I
M
N
A
A
N
K
----
K
Q
T
L
V
D
L
A
A
R
L
N
I
A
T
E
N
I
I
A
C
G
D
G
A
N
D
L
P
M
L
E
H
A
G
T
G
I
A
W
K
A
K
P
---
V
---
V
R
E
K
I
H
H
Q
I
N
Y
H
G
F
E
L
L
L
F
L
I
E
D
E
L
----------
77
HHSearch
79.76
34%
-90
- C2 -
3M1Y
3
?
A:
[2-205]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
Q
K
L
A
V
F
D
F
D
S
T
L
V
N
A
E
T
I
E
S
L
A
R
A
W
G
V
F
D
E
V
K
T
I
T
L
K
----
E
T
D
F
H
K
S
L
I
L
R
V
S
K
L
K
N
M
P
L
K
L
A
K
E
V
C
-
E
--
S
L
P
L
F
E
G
A
L
E
L
V
S
A
L
K
E
K
N
Y
K
V
V
C
F
S
G
G
F
D
L
A
T
N
H
Y
R
D
L
L
H
L
D
--
A
A
F
S
N
T
L
I
V
E
-
N
D
A
L
N
G
L
V
T
-
G
H
M
M
F
S
H
S
K
----
G
E
M
L
L
V
L
Q
R
L
L
N
I
S
K
T
N
T
L
V
V
G
D
G
A
N
D
L
S
M
F
K
H
A
H
I
K
I
A
F
N
A
K
E
---
V
---
L
K
Q
H
A
T
H
C
I
N
E
P
D
L
A
L
I
K
P
L
---------------
9
PsiBlast_PDB
78.80
34%
-89
- C2 -
3M1Y
3
?
A:
[3-202]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
K
L
A
V
F
D
F
D
S
T
L
V
N
A
E
T
I
E
S
L
A
R
A
W
G
V
F
D
E
V
K
T
I
T
L
K
----
E
T
D
F
H
K
S
L
I
L
R
V
S
K
L
K
N
M
P
L
K
L
A
K
E
V
C
-
E
--
S
L
P
L
F
E
G
A
L
E
L
V
S
A
L
K
E
K
N
Y
K
V
V
C
F
S
G
G
F
D
L
A
T
N
H
Y
R
D
L
L
H
L
D
--
A
A
F
S
N
T
L
I
V
E
-
N
D
A
L
N
G
L
V
T
-
G
H
M
M
F
S
H
S
K
----
G
E
M
L
L
V
L
Q
R
L
L
N
I
S
K
T
N
T
L
V
V
G
D
G
A
N
D
L
S
M
F
K
H
A
H
I
K
I
A
F
N
A
K
E
---
V
---
L
K
Q
H
A
T
H
C
I
N
E
P
D
L
A
L
I
K
P
L
---------------
80
HHSearch
68.34
31%
-80
- C2 -
1NNL
4
SERB_HUMAN
A:
[12-221]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
A
D
A
V
C
F
D
V
D
S
T
V
I
R
E
E
G
I
D
E
L
A
K
I
C
G
V
E
D
A
V
------------
P
F
K
A
A
L
T
E
R
L
A
L
-
I
Q
P
S
R
E
Q
V
Q
R
L
I
-
A
E
Q
P
P
H
L
T
P
G
I
R
E
L
V
S
R
L
Q
E
R
N
V
Q
V
F
L
I
S
G
G
F
R
S
I
V
E
H
V
A
S
K
L
N
I
P
AT
N
V
F
A
N
R
L
K
F
Y
F
N
G
E
Y
A
G
F
D
E
T
Q
P
T
A
E
S
G
G
K
----
G
K
V
I
K
L
L
K
E
K
F
--
H
F
K
K
I
I
M
I
G
D
G
A
T
D
M
E
A
C
P
P
A
D
A
F
I
G
F
G
G
N
V
IR
Q
Q
---
V
K
D
N
A
K
W
Y
I
T
D
F
V
--
E
L
L
G
----------------
24
PsiBlast_CBE
65.95
32%
-81
- C2 -
1L8L
1
SERB_HUMAN
B:
[17-215]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
C
F
D
V
D
S
T
V
I
R
E
E
G
I
D
E
L
A
K
I
C
G
V
E
D
A
V
S
E
M
T
R
R
A
M
G
G
A
V
P
F
K
A
A
L
T
E
R
L
A
L
I
Q
P
S
R
E
Q
V
Q
R
L
I
A
E
Q
--
P
P
H
L
T
P
G
I
R
E
L
V
S
R
L
Q
E
R
N
V
Q
V
F
L
I
S
G
G
F
R
S
I
V
E
H
V
A
S
K
L
N
I
P
AT
N
V
F
A
N
R
L
K
F
----
Y
F
N
G
E
Y
A
-
G
F
D
E
T
Q
P
T
A
ESGG
K
G
K
V
I
K
F
L
K
E
K
-
F
H
F
K
K
I
I
M
I
G
D
G
A
T
D
M
E
A
C
P
P
A
D
A
F
I
G
F
G
G
N
V
---
I
RQQ
V
K
D
N
A
K
W
Y
I
T
D
F
V
E
L
L
G
E
L
E
E
--------------
10
PsiBlast_PDB
65.15
32%
-80
- C2 -
1L8L
1
SERB_HUMAN
A:
[17-215]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
C
F
D
V
D
S
T
V
I
R
E
E
G
I
D
E
L
A
K
I
C
G
V
E
D
A
V
S
E
M
T
R
R
A
M
G
G
A
V
P
F
K
A
A
L
T
E
R
L
A
L
I
Q
P
S
R
E
Q
V
Q
R
L
I
A
E
Q
--
P
P
H
L
T
P
G
I
R
E
L
V
S
R
L
Q
E
R
N
V
Q
V
F
L
I
S
G
G
F
R
S
I
V
E
H
V
A
S
K
L
N
I
P
AT
N
V
F
A
N
R
L
K
F
----
Y
F
N
G
E
Y
A
-
G
F
D
E
T
Q
P
T
A
ESGG
K
G
K
V
I
K
F
L
K
E
K
-
F
H
F
K
K
I
I
M
I
G
D
G
A
T
D
M
E
A
C
P
P
A
D
A
F
I
G
F
G
G
N
V
---
I
R
Q
Q
V
K
D
N
A
K
W
Y
I
T
D
F
V
E
L
L
G
E
L
E
E
--------------
23
PsiBlast_CBE
64.76
32%
-79
- C2 -
1L8O
2
SERB_HUMAN
B:
[17-215]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
C
F
D
V
D
S
T
V
I
R
E
E
G
I
D
E
L
A
K
I
C
G
V
E
D
A
V
S
E
M
T
R
R
A
M
G
G
A
V
P
F
K
A
A
L
T
E
R
L
A
L
I
Q
P
S
R
E
Q
V
Q
R
L
I
A
E
Q
--
P
P
H
L
T
P
G
I
R
E
L
V
S
R
L
Q
E
R
N
V
Q
V
F
L
I
S
G
G
F
R
S
I
V
E
H
V
A
S
K
L
N
I
P
AT
N
V
F
A
N
R
L
K
F
----
Y
F
N
G
E
Y
A
-
G
F
D
E
T
Q
P
T
A
ESGG
K
G
K
V
I
K
F
L
K
E
K
-
F
H
F
K
K
I
I
M
I
G
D
G
A
T
D
M
E
A
C
P
P
A
D
A
F
I
G
F
G
G
N
V
---
I
RQQ
V
K
D
N
A
K
W
Y
I
T
D
F
V
E
L
L
G
E
L
E
E
--------------