@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0632: (2015-12-02 )
MKKRQKIWRGLSVTLLILSQIPFGILVQGETQDTNQALGKVIVKKTGDNATPLGKATFVLKNDNDKSETSHETVEGSGEATFENIKPGDYTLREETAPIGYKKTDKTWKVKVADNGATIIEGMDADKAEKRKEVLNAQYPKSAIYEDTKENYPLVNVEGSKVGEQYKALNPINGKDGRREIAEGWLSKKITGVNDLDKNKYKIELTVEGKTTVETKELNQPLDVVVLLDNSNSMNNERANNSQRALKAGEAVEKLIDKITSNKDNRVALVTYASTIFDGTEATVSKGVADQNGKALNDSVSWDYHKTTFTATTHNYSYLNLTNDANEVNILKSRIPKEAEHINGDRTLYQFGATFTQKALMKANEILETQSSNARKKLIFHVTDGVPTMSYAINFNPYISTSYQNQFNSFLNKIPDRSGILQEDFIINGDDYQIVKGDGESFKLFSDRKVPVTGGTTQAAYRVPQNQLSVMSNEGYAINSGYIYLYWRDYNWVYPFDPKTKKVSATKQIKTHGEPTTLYFNGNIRPKGYDIFTVGIGVNGDPGATPLEAEKFMQSISSKTENYTNVDDTNKIYDELNKYFKTIVEEKHSIVDGNVTDPMGEMIEFQLKNGQSFTHDDYVLVGNDGSQLKNGVALGGPNSDGGILKDVTVTYDKTSQTIKINHLNLGSGQKVVLTYDVRLKDNYISNKFYNTNNRTTLSPKSEKEPNTIRDFPIPKIRDVREFPVLTISNQKKMGEVEFIKVNKDKHSESLLGAKFQLQIEKDFSGYKQFVPEGSDVTTKNDGKIYFKALQDGNYKLYEISSPDGYIEVKTKPVVTFTIQNGEVTNLKADPNANKNQIGYLEGNGKHLITNTPKRPPGVFPKTGGIGTIVYILVGSTFMILTICSFRRKQL
Atome Classification :
(20 SA)
.........10........20........30........40........-50........60........70-----.........80........90........---------100.......110.......120.--..---------------....130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260...-.....270.......280.......290.......300.......310.......320..-...--------..330--........340......-.350--.......360.......-370----.--........380.......390....-...-400........410.......420......--.--430.......440...-....450.......460.......470....-----.-----..480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760---....-....770--..----......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MK
K
R
Q
K
I
W
R
G
L
S
V
T
L
L
I
L
S
QIP
F
G
I
L
V
QGETQ
D
T
N
Q
A
L
G
K
V
I
V
KKTGDN-ATPLG
K
A
T
F
V
L
KNDNDKSETS------HETVEGSGE
A
T
FENIKPG
D
Y
T
L
REETAPI---------GYKKTD
K
T
W
K
V
K
VADN
G
A
T
I
I
EGM--DA---------------
D
K
A
E
K
R
K
E
V
L
NAQY
P
K
S
A
I
YEDTKENY
P
L
V
N
VE
G
S
KV
G
E
Q
Y
KALNPING
K
D
G
R
R
E
I
A
E
G
W
L
S
KKITGVNDLDK
N
K
Y
K
I
E
L
T
VEGK
T
T
V
E
T
K
ELNQPL
D
V
V
V
L
LDNSNSMNNERAN
N
S
Q
R
A
L
K
A
G
E
A
V
E
K
L
I
D
K
I
TS-NKD-N
R
V
A
L
V
T
Y
A
S
T
IFDGT
E
A
T
V
SKGVADQNGKALNDSV
S
W
D
Y
H
K
T
T
F
T
A
TTH
N
Y
S
Y
L
N
LTND-A
N
E
--------
V
N
I
L
---
K
S
RIP
K
E
A
EHINGD
R
T
L
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
N
E
I
L
ET-Q------S--SNA
R
K
K
L
I
F
H
VTDGVP
T
M
S
Y
A
I
NFN-PYI-S-
T
S
Y
Q
N
Q
F
N
S
F
L
N
KIPDRSGILQE
D
F
I
IN--G--D
D
Y
Q
I
V
KGDGE
S
F
K
L
F-SDRKVPVTGGTTQ
A
A
Y
RV
P
Q
N
Q
L
S
VMSNE
G
Y
-----
A
-----
I
NS
G
Y
I
Y
L
Y
W
R
DY
N
W
V
YPFDPKTKKVSA
T
K
QIKTHGE
P
T
T
L
Y
FNGNIRPK
G
Y
D
I
F
T
V
G
IGVNGDPGAT
P
L
E
A
E
K
F
M
Q
S
I
S
SKTENYTNVD
D
T
N
K
I
Y
D
E
L
N
K
Y
F
K
T
I
V
E
E
K
HSIVDGNVTDPM
G
E
M
I
E
F
Q
LKNGQSFTHD
D
Y
V
L
VGND
G
S
Q
LKN
G
V
ALGGPNSDG
G
I
L
K
D
V
T
V
T
YDKTS
Q
T
I
K
I
N
H
L
NLGSG
Q
K
V
V
L
T
Y
D
V
R
L
KDNYISN
K
F
YNTNNRTTLSPKSEKEPNTIRDFPIP
K
I
R
D
V
R
EF
P
V
L
T
ISNQKKMG
E
V
E
F
I
K
VNKDKHS
E
S
LLG
A
K
F
Q
L
Q
IEK----DFS
G
-
Y
K
Q
FVP---EG----SDVTTKND
G
K
I
Y
F
K
A
LQDG
N
Y
K
L
Y
E
ISSPD
G
Y
I
E
V
KTK
P
V
V
T
F
T
IQNG
E
V
T
NLKADPNANK
N
Q
I
G
Y
LEGNG
K
H
L
ITNTPKRPPGVFPKTGGI
G
T
I
V
Y
I
L
VGS
T
F
M
I
L
T
I
C
S
F
R
RKQL
17
HHSearch
89.26
100%
-57
- C3 -
3TXA
9
?
A:
[90-672]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
Y
P
K
S
A
I
Y
E
D
T
K
E
N
Y
P
L
V
N
V
E
G
S
K
V
G
E
Q
Y
K
A
L
N
P
I
N
G
K
D
G
R
R
E
I
A
E
G
W
L
S
K
K
I
T
G
V
N
D
L
D
K
N
K
Y
K
I
E
L
T
V
E
G
K
T
T
V
E
T
K
E
L
N
Q
P
L
D
V
V
V
L
L
D
N
S
N
S
M
N
N
E
R
A
N
N
S
Q
R
A
L
K
A
G
E
A
V
E
K
L
I
D
K
I
T
S
-
N
K
D
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
A
T
V
S
K
G
V
A
D
Q
N
G
K
A
L
N
D
S
V
S
W
D
Y
H
K
T
T
F
T
A
T
T
H
N
Y
S
Y
L
N
L
T
N
D
-
A
N
E
--------
V
N
I
L
---
K
S
R
I
P
K
E
A
E
H
I
N
G
D
R
T
L
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
N
E
I
L
E
T
-
Q
------
S
--
S
N
A
R
K
K
L
I
F
H
V
T
D
G
V
P
T
M
S
Y
A
I
N
F
N
-
P
Y
I
-
S
-
T
S
Y
Q
N
Q
F
N
S
F
L
N
K
I
P
D
R
S
G
I
L
Q
E
D
F
I
I
N
--
G
--
D
D
Y
Q
I
V
K
G
D
G
E
S
F
K
L
F
-
S
D
R
K
V
P
V
T
G
G
T
T
Q
A
A
Y
R
V
P
Q
N
Q
L
S
V
M
S
N
E
G
Y
-----
A
-----
I
N
S
G
Y
I
Y
L
Y
W
R
D
Y
N
W
V
Y
P
F
D
P
K
T
K
K
V
S
A
T
K
Q
I
K
T
H
G
E
P
T
T
L
Y
F
N
G
N
I
R
P
K
G
Y
D
I
F
T
V
G
I
G
V
N
G
D
P
G
A
T
P
L
E
A
E
K
F
M
Q
S
I
S
S
K
T
E
N
Y
T
N
V
D
D
T
N
K
I
Y
D
E
L
N
K
Y
F
K
T
I
V
E
E
K
H
S
I
V
D
G
N
V
T
D
P
M
G
E
M
I
E
F
Q
L
K
N
G
Q
S
F
T
H
D
D
Y
V
L
V
G
N
D
G
S
Q
L
K
N
G
V
A
L
G
G
P
N
S
D
G
G
I
L
K
D
V
T
V
T
Y
D
K
T
S
Q
T
I
K
I
N
H
L
N
L
G
S
G
Q
K
V
V
L
T
Y
D
V
R
L
K
D
N
Y
I
S
N
K
F
Y
N
T
N
N
R
T
T
L
S
P
K
S
E
K
E
P
N
T
I
R
D
F
P
I
P
K
I
R
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.26
100%
-57
- C3 -
3TXA
9
?
A:
[90-672]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
Y
P
K
S
A
I
Y
E
D
T
K
E
N
Y
P
L
V
N
V
E
G
S
K
V
G
E
Q
Y
K
A
L
N
P
I
N
G
K
D
G
R
R
E
I
A
E
G
W
L
S
K
K
I
T
G
V
N
D
L
D
K
N
K
Y
K
I
E
L
T
V
E
G
K
T
T
V
E
T
K
E
L
N
Q
P
L
D
V
V
V
L
L
D
N
S
N
S
M
N
N
E
R
A
N
N
S
Q
R
A
L
K
A
G
E
A
V
E
K
L
I
D
K
I
T
S
-
N
K
D
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
A
T
V
S
K
G
V
A
D
Q
N
G
K
A
L
N
D
S
V
S
W
D
Y
H
K
T
T
F
T
A
T
T
H
N
Y
S
Y
L
N
L
T
N
D
-
A
N
E
--------
V
N
I
L
---
K
S
R
I
P
K
E
A
E
H
I
N
G
D
R
T
L
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
N
E
I
L
E
T
-
Q
------
S
--
S
N
A
R
K
K
L
I
F
H
V
T
D
G
V
P
T
M
S
Y
A
I
N
F
N
-
P
Y
I
-
S
-
T
S
Y
Q
N
Q
F
N
S
F
L
N
K
I
P
D
R
S
G
I
L
Q
E
D
F
I
I
N
--
G
--
D
D
Y
Q
I
V
K
G
D
G
E
S
F
K
L
F
-
S
D
R
K
V
P
V
T
G
G
T
T
Q
A
A
Y
R
V
P
Q
N
Q
L
S
V
M
S
N
E
G
Y
-----
A
-----
I
N
S
G
Y
I
Y
L
Y
W
R
D
Y
N
W
V
Y
P
F
D
P
K
T
K
K
V
S
A
T
K
Q
I
K
T
H
G
E
P
T
T
L
Y
F
N
G
N
I
R
P
K
G
Y
D
I
F
T
V
G
I
G
V
N
G
D
P
G
A
T
P
L
E
A
E
K
F
M
Q
S
I
S
S
K
T
E
N
Y
T
N
V
D
D
T
N
K
I
Y
D
E
L
N
K
Y
F
K
T
I
V
E
E
K
H
S
I
V
D
G
N
V
T
D
P
M
G
E
M
I
E
F
Q
L
K
N
G
Q
S
F
T
H
D
D
Y
V
L
V
G
N
D
G
S
Q
L
K
N
G
V
A
L
G
G
P
N
S
D
G
G
I
L
K
D
V
T
V
T
Y
D
K
T
S
Q
T
I
K
I
N
H
L
N
L
G
S
G
Q
K
V
V
L
T
Y
D
V
R
L
K
D
N
Y
I
S
N
K
F
Y
N
T
N
N
R
T
T
L
S
P
K
S
E
K
E
P
N
T
I
R
D
F
P
I
P
K
I
R
D
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
89.22
51%
-46
- C3 -
2WW8
5
?
A:
[46-860]
------------------------------------
A
I
G
K
V
V
I
K
E
T
G
E
G
-
G
A
L
L
G
D
A
V
F
E
L
K
N
N
T
D
G
T
T
V
S
------
Q
R
T
E
A
Q
T
G
E
A
I
F
S
N
I
K
P
G
T
Y
T
L
T
E
A
Q
P
P
V
---------
G
Y
K
P
S
T
K
Q
W
T
V
E
V
E
K
N
G
R
T
T
V
Q
G
--------------------
E
Q
V
E
N
R
E
E
A
L
S
D
Q
Y
P
Q
T
G
T
Y
P
D
V
Q
T
P
Y
Q
I
I
K
V
D
G
S
E
K
N
G
Q
H
K
A
L
N
P
---
N
P
Y
E
R
V
I
P
E
G
T
L
S
K
R
I
Y
Q
V
N
N
L
D
D
N
Q
Y
G
I
E
L
T
V
S
G
K
T
V
Y
E
Q
K
D
K
S
V
P
L
D
V
V
I
L
L
D
N
S
N
S
M
S
N
I
R
N
K
N
A
R
R
A
E
R
A
G
E
A
T
R
S
L
I
D
K
I
T
S
-
D
S
E
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
F
T
V
E
K
G
V
A
D
K
N
G
K
R
L
N
D
S
L
F
W
N
Y
D
Q
T
S
F
T
T
N
T
K
D
Y
S
Y
L
K
L
T
N
D
-
K
N
D
--------
I
V
E
L
---
K
N
K
V
P
T
E
A
E
D
H
D
G
N
R
L
M
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
D
E
I
L
T
Q
-
Q
------
A
--
R
Q
N
S
Q
K
V
I
F
H
I
T
D
G
V
P
T
M
S
Y
P
I
N
F
N
H
A
T
F
-
A
-
P
S
Y
Q
N
Q
L
N
A
F
F
S
K
S
P
N
K
D
G
I
L
L
S
D
F
I
T
Q
--
A
TS
G
E
H
T
I
V
R
G
D
G
Q
S
Y
Q
M
F
-
T
D
K
T
V
Y
E
K
G
A
P
--
A
A
F
P
V
K
P
E
K
Y
S
E
M
K
A
A
G
Y
-----
A
VIGDP
I
N
G
G
Y
I
W
L
N
W
R
E
S
I
L
A
Y
P
F
N
------
S
N
T
A
K
I
T
N
H
G
D
P
T
R
W
Y
Y
N
G
N
I
A
P
D
G
Y
D
V
F
T
V
G
I
G
I
N
G
D
P
G
T
D
E
A
T
A
T
S
F
M
Q
S
I
S
S
K
P
E
N
Y
T
N
V
T
D
T
T
K
I
L
E
Q
L
N
R
Y
F
H
T
I
V
T
E
K
K
S
I
E
N
G
T
I
T
D
P
M
G
E
L
I
D
L
Q
L
G
T
D
G
R
F
D
P
A
D
Y
T
L
T
A
N
D
G
S
R
L
E
N
G
Q
A
V
G
G
P
Q
N
D
G
G
L
L
K
N
A
K
V
L
Y
D
T
T
E
K
R
I
R
V
T
G
L
Y
L
G
T
D
E
K
V
T
L
T
Y
N
V
R
L
N
D
E
F
V
S
N
K
F
Y
D
T
N
G
R
T
T
L
H
P
K
-
E
V
E
Q
N
T
V
R
D
F
P
I
P
K
I
R
D
V
R
K
Y
P
E
I
T
I
S
K
E
K
K
L
G
D
I
E
F
I
K
V
N
K
N
-
D
K
K
P
L
R
G
A
V
F
S
L
Q
K
Q
H
PDYP
D
I
Y
G
-
A
I
D
Q
N
G
---
T
Y
----
Q
N
V
R
T
G
E
D
G
K
L
T
F
K
N
L
S
D
G
K
Y
R
L
F
E
N
S
E
P
A
G
Y
K
P
V
Q
N
K
P
I
V
A
F
Q
I
V
N
G
E
V
R
D
V
T
S
I
V
P
Q
D
I
-
P
A
G
Y
E
F
T
N
D
K
H
Y
I
T
N
E
P
I
P
P
K
----------------------------------
16
HHSearch
87.47
51%
-47
- C3 -
2WW8
5
?
A:
[46-860]
------------------------------------
A
I
G
K
V
V
I
K
E
T
G
E
G
-
G
A
L
L
G
D
A
V
F
E
L
K
N
N
T
D
G
T
T
V
S
------
Q
R
T
E
A
Q
T
G
E
A
I
F
S
N
I
K
P
G
T
Y
T
L
T
E
A
Q
P
P
V
---------
G
Y
K
P
S
T
K
Q
W
T
V
E
V
E
K
N
G
R
T
T
V
Q
G
E
Q
V
E
N
R
E
E
A
L
S
DQYPQ
T
G
T
Y
P
D
V
Q
T
P
Y
Q
I
I
K
V
D
G
S
--------------------
E
K
N
G
Q
H
K
---
A
L
N
P
N
P
Y
E
R
V
I
P
E
G
T
L
S
K
R
I
Y
Q
V
N
N
L
D
D
N
Q
Y
G
I
E
L
T
V
S
G
K
T
V
Y
E
Q
K
D
K
S
V
P
L
D
V
V
I
L
L
D
N
S
N
S
M
S
N
I
R
N
K
N
A
R
R
A
E
R
A
G
E
A
T
R
S
L
I
D
K
I
T
S
-
D
S
E
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
F
T
V
E
K
G
V
A
D
K
N
G
K
R
L
N
D
S
L
F
W
N
Y
D
Q
T
S
F
T
T
N
T
K
D
Y
S
Y
L
K
L
T
N
D
-
K
N
D
--------
I
V
E
L
---
K
N
K
V
P
T
E
A
E
D
H
D
G
N
R
L
M
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
D
E
I
L
T
Q
-
Q
------
A
--
R
Q
N
S
Q
K
V
I
F
H
I
T
D
G
V
P
T
M
S
Y
P
I
N
F
N
-
H
A
T
F
A
-
P
S
Y
Q
N
Q
L
N
A
F
F
S
K
S
P
N
K
D
G
I
L
L
S
D
F
I
T
Q
AT
S
--
G
E
H
T
I
V
R
G
D
G
Q
S
Y
Q
M
F
T
D
K
T
V
Y
E
--
K
G
A
P
A
A
-
F
P
V
K
P
E
K
Y
S
E
M
K
A
A
G
Y
AVIGD
P
-----
I
N
G
G
Y
I
W
L
N
W
R
E
S
I
L
A
Y
P
F
N
S
N
T
------
A
K
I
T
N
H
G
D
P
T
R
W
Y
Y
N
G
N
I
A
P
D
G
Y
D
V
F
T
V
G
I
G
I
N
G
D
P
G
T
D
E
A
T
A
T
S
F
M
Q
S
I
S
S
K
P
E
N
Y
T
N
V
T
D
T
T
K
I
L
E
Q
L
N
R
Y
F
H
T
I
V
T
E
K
K
S
I
E
N
G
T
I
T
D
P
M
G
E
L
I
D
L
Q
L
G
T
D
G
R
F
D
P
A
D
Y
T
L
T
A
N
D
G
S
R
L
E
N
G
Q
A
V
G
G
P
Q
N
D
G
G
L
L
K
N
A
K
V
L
Y
D
T
T
E
K
R
I
R
V
T
G
L
Y
L
G
T
D
E
K
V
T
L
T
Y
N
V
R
L
N
D
E
F
V
S
N
K
F
Y
D
T
N
G
R
T
T
L
H
P
K
E
V
E
-
Q
N
T
V
R
D
F
P
I
P
K
I
R
D
V
R
K
Y
P
E
I
T
I
S
K
E
K
K
L
G
D
I
E
F
I
K
V
N
K
N
D
-
K
K
P
L
R
G
A
V
F
S
L
Q
K
Q
H
----
P
D
Y
P
D
I
Y
G
A
I
D
QNG
T
Y
----
Q
N
V
R
T
G
E
D
G
K
L
T
F
K
N
L
S
D
G
K
Y
R
L
F
E
N
S
E
P
A
G
Y
K
P
V
Q
N
K
P
I
V
A
F
Q
I
V
N
G
E
V
R
D
V
T
S
I
V
P
-
Q
D
I
P
A
G
Y
E
F
T
N
D
K
H
Y
I
T
N
E
P
I
P
P
K
----------------------------------
38
Fugue
86.68
51%
-42
- C3 -
2WW8
5
?
A:
[46-860]
------------------------------------
A
I
G
K
V
V
I
K
E
T
G
E
G
-
G
A
L
L
G
D
A
V
F
E
L
K
N
N
T
D
G
T
T
V
S
------
Q
R
T
E
A
Q
T
G
E
A
I
F
S
N
I
K
P
G
T
Y
T
L
T
E
A
Q
P
P
V
---------
G
Y
K
P
S
T
K
Q
W
T
V
E
V
E
K
N
G
R
T
T
V
Q
G
--------------------
E
Q
V
E
N
R
E
E
A
L
S
D
Q
Y
P
Q
T
G
T
Y
P
D
V
Q
T
P
Y
Q
I
I
K
V
D
G
S
E
K
N
G
Q
H
K
A
L
N
P
N
---
P
Y
E
R
V
I
P
E
G
T
L
S
K
R
I
Y
Q
V
N
N
L
D
D
N
Q
Y
G
I
E
L
T
V
S
G
K
T
V
Y
E
Q
K
D
K
S
V
P
L
D
V
V
I
L
L
D
N
S
N
S
M
S
N
I
R
N
K
N
A
R
R
A
E
R
A
G
E
A
T
R
S
L
I
D
K
I
T
S
-
D
S
E
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
F
T
V
E
K
G
V
A
D
K
N
G
K
R
L
N
D
S
L
F
W
N
Y
D
Q
T
S
F
T
T
N
T
K
D
Y
S
Y
L
K
L
T
N
D
-
K
N
D
--------
I
V
E
L
---
K
N
K
V
P
T
E
A
E
D
H
D
G
N
R
L
M
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
D
E
I
L
T
Q
-
Q
------
A
--
R
Q
N
S
Q
K
V
I
F
H
I
T
D
G
V
P
T
M
S
Y
P
I
N
F
N
-
H
A
T
-
F
A
P
S
Y
Q
N
Q
L
N
A
F
F
S
K
S
P
N
K
D
G
I
L
L
S
D
F
I
T
Q
--
A
--
T
S
G
E
H
T
I
V
R
G
D
G
Q
S
Y
Q
-
M
F
T
D
K
T
V
Y
E
K
G
A
P
A
A
F
P
V
K
P
E
K
Y
S
E
M
K
A
A
G
Y
-----
A
-----
V
I
G
D
P
I
N
G
G
Y
I
W
L
N
W
R
E
S
I
L
A
Y
P
F
N
-
S
N
T
A
K
I
T
N
H
G
D
P
T
R
W
Y
Y
N
G
N
I
A
P
D
G
Y
D
V
F
T
V
G
I
G
I
N
G
D
P
G
T
D
E
A
T
A
T
S
F
M
Q
S
I
S
S
K
P
E
N
Y
T
N
V
T
D
T
T
K
I
L
E
Q
L
N
R
Y
F
H
T
I
V
T
E
K
K
S
I
E
N
G
T
I
T
D
P
M
G
E
L
I
D
L
Q
L
G
T
D
G
R
F
D
P
A
D
Y
T
L
T
A
N
D
G
S
R
L
E
N
G
Q
A
V
G
G
P
Q
N
D
G
G
L
L
K
N
A
K
V
L
Y
D
T
T
E
K
R
I
R
V
T
G
L
Y
L
G
T
D
E
K
V
T
L
T
Y
N
V
R
L
N
D
E
F
V
S
N
K
F
Y
D
T
N
G
R
T
T
L
H
P
K
E
-
V
E
Q
N
T
V
R
D
F
P
I
P
K
I
R
D
V
R
K
Y
P
E
I
T
I
S
K
E
K
K
L
G
D
I
E
F
I
K
V
N
K
N
-
D
K
K
P
L
R
G
A
V
F
S
L
Q
K
Q
H
----
P
D
Y
P
-
D
I
Y
G
A
I
---
D
Q
NGTY
Q
N
V
R
T
G
E
D
G
K
L
T
F
K
N
L
S
D
G
K
Y
R
L
F
E
N
S
E
P
A
G
Y
K
P
V
Q
N
K
P
I
V
A
F
Q
I
V
N
G
E
V
R
D
V
T
S
I
V
P
-
Q
D
I
P
A
G
Y
E
F
T
N
D
K
H
Y
I
T
N
E
P
I
P
P
K
----------------------------------
18
HHSearch
73.46
100%
-66
- C3 -
3TVY
2
?
A:
[9-373]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
L
D
V
V
V
L
L
D
N
S
N
S
M
N
N
E
R
A
N
N
S
Q
R
A
L
K
A
G
E
A
V
E
K
L
I
D
K
I
T
S
-
N
K
D
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
A
T
V
S
K
G
V
A
D
Q
N
G
K
A
L
N
D
S
V
S
W
D
Y
H
K
T
T
F
T
A
T
T
H
N
Y
S
Y
L
N
L
T
N
D
-
A
N
E
--------
V
N
I
L
---
K
S
R
I
P
K
E
A
E
H
I
N
G
D
R
T
L
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
N
E
I
L
E
T
-
Q
------
S
--
S
N
A
R
K
K
L
I
F
H
V
T
D
G
V
P
T
M
S
Y
A
I
N
F
N
-
P
Y
I
-
S
-
T
S
Y
Q
N
Q
F
N
S
F
L
N
K
I
P
D
R
S
G
I
L
Q
E
D
F
I
I
N
--
G
--
D
D
Y
Q
I
V
K
G
D
G
E
S
F
K
L
F
-
S
D
R
K
V
P
V
T
G
G
T
T
Q
A
A
Y
R
V
P
Q
N
Q
L
S
V
M
S
N
E
G
Y
-----
A
-----
I
N
S
G
Y
I
Y
L
Y
W
R
D
Y
N
W
V
Y
P
F
D
P
K
T
K
K
V
S
A
T
K
Q
I
K
T
H
G
E
P
T
T
L
Y
F
N
G
N
I
R
P
K
G
Y
D
I
F
T
V
G
I
G
V
N
G
D
P
G
A
T
P
L
E
A
E
K
F
M
Q
S
I
S
S
K
T
E
N
Y
T
N
V
D
D
T
N
K
I
Y
D
E
L
N
K
Y
F
K
T
I
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
73.46
100%
-66
- C3 -
3TVY
2
?
A:
[9-373]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
L
D
V
V
V
L
L
D
N
S
N
S
M
N
N
E
R
A
N
N
S
Q
R
A
L
K
A
G
E
A
V
E
K
L
I
D
K
I
T
S
-
N
K
D
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
A
T
V
S
K
G
V
A
D
Q
N
G
K
A
L
N
D
S
V
S
W
D
Y
H
K
T
T
F
T
A
T
T
H
N
Y
S
Y
L
N
L
T
N
D
-
A
N
E
--------
V
N
I
L
---
K
S
R
I
P
K
E
A
E
H
I
N
G
D
R
T
L
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
N
E
I
L
E
T
-
Q
------
S
--
S
N
A
R
K
K
L
I
F
H
V
T
D
G
V
P
T
M
S
Y
A
I
N
F
N
-
P
Y
I
-
S
-
T
S
Y
Q
N
Q
F
N
S
F
L
N
K
I
P
D
R
S
G
I
L
Q
E
D
F
I
I
N
--
G
--
D
D
Y
Q
I
V
K
G
D
G
E
S
F
K
L
F
-
S
D
R
K
V
P
V
T
G
G
T
T
Q
A
A
Y
R
V
P
Q
N
Q
L
S
V
M
S
N
E
G
Y
-----
A
-----
I
N
S
G
Y
I
Y
L
Y
W
R
D
Y
N
W
V
Y
P
F
D
P
K
T
K
K
V
S
A
T
K
Q
I
K
T
H
G
E
P
T
T
L
Y
F
N
G
N
I
R
P
K
G
Y
D
I
F
T
V
G
I
G
V
N
G
D
P
G
A
T
P
L
E
A
E
K
F
M
Q
S
I
S
S
K
T
E
N
Y
T
N
V
D
D
T
N
K
I
Y
D
E
L
N
K
Y
F
K
T
I
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_CBE
71.39
99%
-61
- C3 -
3TW0
2
?
C:
[9-368]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
L
D
V
V
V
L
L
D
N
S
N
S
M
N
N
E
R
A
N
N
S
Q
R
A
L
K
A
G
E
A
V
E
K
L
I
D
K
I
T
S
-
N
K
D
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
A
T
V
S
K
G
V
A
D
Q
N
G
K
A
L
N
D
S
V
S
W
D
Y
H
K
T
T
F
T
A
T
T
H
N
Y
S
Y
L
N
L
T
N
D
-
A
N
E
--------
V
N
I
L
---
K
S
R
I
P
K
E
A
E
H
I
N
G
D
R
T
L
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
N
E
I
L
E
T
-
Q
------
S
--
S
N
A
R
K
K
L
I
F
H
V
T
D
G
V
P
T
M
S
Y
A
I
N
F
N
-
P
Y
I
-
S
-
T
S
Y
Q
N
Q
F
N
S
F
L
N
K
I
P
D
R
S
G
I
L
Q
E
D
F
I
I
N
--
G
--
D
D
Y
Q
I
V
K
G
D
G
E
S
F
K
L
F
-
S
D
R
K
V
P
V
T
G
G
T
T
Q
A
A
Y
R
V
P
Q
N
Q
L
S
V
M
S
N
E
G
Y
-----
A
-----
I
N
S
G
Y
I
Y
L
Y
W
R
D
Y
N
W
V
Y
P
F
D
P
K
T
K
K
V
S
A
T
K
Q
I
K
T
H
G
E
P
T
T
L
Y
F
N
G
N
I
R
P
K
G
Y
D
I
F
T
V
G
I
G
V
N
G
D
P
G
A
T
P
L
E
A
E
K
F
M
Q
S
I
S
S
K
T
E
N
Y
C
N
V
D
D
T
N
C
I
Y
D
E
L
N
K
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_CBE
71.16
99%
-61
- C3 -
3TW0
2
?
B:
[9-369]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
L
D
V
V
V
L
L
D
N
S
N
S
M
N
N
E
R
A
N
N
S
Q
R
A
L
K
A
G
E
A
V
E
K
L
I
D
K
I
T
S
-
N
K
D
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
A
T
V
S
K
G
V
A
D
Q
N
G
K
A
L
N
D
S
V
S
W
D
Y
H
K
T
T
F
T
A
T
T
H
N
Y
S
Y
L
N
L
T
N
D
-
A
N
E
--------
V
N
I
L
---
K
S
R
I
P
K
E
A
E
H
I
N
G
D
R
T
L
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
N
E
I
L
E
T
-
Q
------
S
--
S
N
A
R
K
K
L
I
F
H
V
T
D
G
V
P
T
M
S
Y
A
I
N
F
N
-
P
Y
I
-
S
-
T
S
Y
Q
N
Q
F
N
S
F
L
N
K
I
P
D
R
S
G
I
L
Q
E
D
F
I
I
N
--
G
--
D
D
Y
Q
I
V
K
G
D
G
E
S
F
K
L
F
-
S
D
R
K
V
P
V
T
G
G
T
T
Q
A
A
Y
R
V
P
Q
N
Q
L
S
V
M
S
N
E
G
Y
-----
A
-----
I
N
S
G
Y
I
Y
L
Y
W
R
D
Y
N
W
V
Y
P
F
D
P
K
T
K
K
V
S
A
T
K
Q
I
K
T
H
G
E
P
T
T
L
Y
F
N
G
N
I
R
P
K
G
Y
D
I
F
T
V
G
I
G
V
N
G
D
P
G
A
T
P
L
E
A
E
K
F
M
Q
S
I
S
S
K
T
E
N
Y
C
N
V
D
D
T
N
C
I
Y
D
E
L
N
K
Y
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_CBE
71.03
99%
-58
- C3 -
3TW0
2
?
D:
[10-366]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
D
V
V
V
L
L
D
N
S
N
S
M
N
N
E
R
A
N
N
S
Q
R
A
L
K
A
G
E
A
V
E
K
L
I
D
K
I
T
S
-
N
K
D
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
A
T
V
S
K
G
V
A
D
Q
N
G
K
A
L
N
D
S
V
S
W
D
Y
H
K
T
T
F
T
A
T
T
H
N
Y
S
Y
L
N
L
T
N
D
-
A
N
E
--------
V
N
I
L
---
K
S
R
I
P
K
E
A
E
H
I
N
G
D
R
T
L
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
N
E
I
L
E
T
-
Q
------
S
--
S
N
A
R
K
K
L
I
F
H
V
T
D
G
V
P
T
M
S
Y
A
I
N
F
N
-
P
Y
I
-
S
-
T
S
Y
Q
N
Q
F
N
S
F
L
N
K
I
P
D
R
S
G
I
L
Q
E
D
F
I
I
N
--
G
--
D
D
Y
Q
I
V
K
G
D
G
E
S
F
K
L
F
-
S
D
R
K
V
P
V
T
G
G
T
T
Q
A
A
Y
R
V
P
Q
N
Q
L
S
V
M
S
N
E
G
Y
-----
A
-----
I
N
S
G
Y
I
Y
L
Y
W
R
D
Y
N
W
V
Y
P
F
D
P
K
T
K
K
V
S
A
T
K
Q
I
K
T
H
G
E
P
T
T
L
Y
F
N
G
N
I
R
P
K
G
Y
D
I
F
T
V
G
I
G
V
N
G
D
P
G
A
T
P
L
E
A
E
K
F
M
Q
S
I
S
S
K
T
E
N
Y
C
N
V
D
D
T
N
C
I
Y
D
E
L
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.34
99%
-60
- C3 -
3TW0
2
?
A:
[9-369]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
L
D
V
V
V
L
L
D
N
S
N
S
M
N
N
E
R
A
N
N
S
Q
R
A
L
K
A
G
E
A
V
E
K
L
I
D
K
I
T
S
-
N
K
D
-
N
R
V
A
L
V
T
Y
A
S
T
I
F
D
G
T
E
A
T
V
S
K
G
V
A
D
Q
N
G
K
A
L
N
D
S
V
S
W
D
Y
H
K
T
T
F
T
A
T
T
H
N
Y
S
Y
L
N
L
T
N
D
-
A
N
E
--------
V
N
I
L
---
K
S
R
I
P
K
E
A
E
H
I
N
G
D
R
T
L
-
Y
Q
F
G
--
A
T
F
T
Q
K
A
L
M
K
A
N
E
I
L
E
T
-
Q
------
S
--
S
N
A
R
K
K
L
I
F
H
V
T
D
G
V
P
T
M
S
Y
A
I
N
F
N
-
P
Y
I
-
S
-
T
S
Y
Q
N
Q
F
N
S
F
L
N
K
I
P
D
R
S
G
I
L
Q
E
D
F
I
I
N
--
G
--
D
D
Y
Q
I
V
K
G
D
G
E
S
F
K
L
F
-
S
D
R
K
V
P
V
T
G
G
T
T
Q
A
A
Y
R
V
P
Q
N
Q
L
S
V
M
S
N
E
G
Y
-----
A
-----
I
N
S
G
Y
I
Y
L
Y
W
R
D
Y
N
W
V
Y
P
F
D
P
K
T
K
K
V
S
A
T
K
Q
I
K
T
H
G
E
P
T
T
L
Y
F
N
G
N
I
R
P
K
G
Y
D
I
F
T
V
G
I
G
V
N
G
D
P
G
A
T
P
L
E
A
E
K
F
M
Q
S
I
S
S
K
T
E
N
Y
C
N
V
D
D
T
N
C
I
Y
D
E
L
N
K
Y
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
45.02
21%
-41
- C3 -
1Q0P
1
A:
[15-142]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
N
I
Y
L
V
L
D
G
S
D
S
I
G
A
S
------
N
F
T
G
A
K
K
S
L
V
N
L
I
E
K
V
A
S
Y
G
V
K
-
P
R
Y
G
L
V
T
Y
A
T
Y
P
K
I
W
V
---------------------------------------
K
V
S
E
A
D
S
S
N
--------
A
D
W
V
---
T
K
Q
L
N
E
I
N
---
Y
--
E
D
H
-
K
L
K
S
--
G
T
N
T
K
K
A
L
Q
A
V
Y
S
M
M
S
W
-
P
DDVPPE
G
--
W
N
R
T
R
H
V
I
I
L
M
T
D
G
L
H
N
M
G
G
D
P
I
T
V
-
I
D
E
-
I
-
R
D
L
L
Y
I
G
K
D
R
K
N
P
R
E
D
Y
L
D
V
Y
V
F
G
V
G
P
L
--
V
--
N
Q
V
N
I
N
A
L
A
S
K
K
D
N
E
Q
-
H
V
F
K
V
K
D
L
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
40.33
17%
-31
- C3 -
1MF7
-
ITAM_HUMAN
A:
[131-247]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
S
D
I
A
F
L
I
D
G
S
G
S
I
I
P
H
------
D
F
R
R
M
K
E
F
V
S
T
V
M
E
Q
L
K
K
--
S
K
-
T
L
F
S
L
M
Q
Y
S
E
E
F
R
I
H
F
T
---------------------------------------
F
K
E
F
--
Q
N
--------
N
P
N
P
---
R
S
L
V
K
----------
P
I
T
Q
L
L
G
--
R
T
H
T
A
T
G
I
R
K
V
V
R
E
L
F
N
-
I
TNG---
A
--
R
K
N
A
F
K
I
L
V
V
I
T
D
G
E
K
F
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
39.50
17%
-35
- C3 -
1IJB
-
A:
[510-627]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
L
L
D
L
V
F
L
L
D
G
S
S
R
L
S
E
A
------
E
F
E
V
L
K
A
F
V
V
D
M
M
E
R
L
R
V
S
Q
K
W
-
V
R
V
A
V
V
E
Y
H
D
G
S
H
A
Y
I
G
---------------------------------------
L
K
D
R
--
K
R
--------
P
S
E
L
---
R
R
I
A
S
----------
Q
V
-
K
Y
A
G
SQ
V
A
S
T
S
E
V
L
K
Y
T
L
F
Q
I
F
S
K
I
------
D
--
R
P
E
A
S
R
I
A
L
L
L
M
A
S
Q
E
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
38.86
18%
-36
- C3 -
3N2N
5
ANTR1_HUMAN
F:
[5-120]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
G
F
D
L
Y
F
I
L
D
K
S
G
S
V
L
H
-------
H
W
N
E
I
Y
Y
F
V
E
Q
L
A
H
K
F
I
--
S
P
Q
-
L
R
M
S
F
I
V
F
S
T
R
G
T
T
L
M
---------------------------------------
K
L
T
E
D
-
R
E
Q
--------
I
R
Q
G
---
L
E
E
L
----------
Q
K
V
-
L
P
G
G
--
D
T
Y
M
H
E
G
F
E
R
A
S
E
Q
I
Y
Y
-
E
------
N
RQ
G
Y
R
T
A
S
V
I
I
A
L
T
D
G
E
L
H
E
D
L
F
F
Y
S
E
-
R
E
A
-
N
-
R
S
R
D
L
G
A
I
V
Y
A
V
G
V
K
D
F
N
E
T
Q
L
A
R
I
A
D
S
--
K
--
D
H
V
F
P
V
N
D
G
F
Q
A
L
Q
G
I
-
I
H
S
I
L
K
K
S
C
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
38.38
21%
-36
- C3 -
1SHU
1
ANTR2_HUMAN
X:
[4-117]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
A
F
D
L
Y
F
V
L
D
K
S
G
S
V
A
N
N
-------
W
I
E
I
Y
N
F
V
Q
Q
L
A
E
R
F
V
S
--
P
E
-
M
R
L
S
F
I
V
F
S
S
Q
A
T
I
I
L
---------------------------------------
P
L
T
G
D
-
R
G
K
--------
I
S
K
G
---
L
E
D
L
-------
K
---
R
V
-
S
P
V
G
--
E
T
Y
I
H
E
G
L
K
L
A
N
E
Q
I
Q
K
-
A
------
G
--
G
L
K
T
S
S
I
I
I
A
L
T
D
G
K
L
D
G
L
V
P
S
Y
A
E
-
K
E
A
-
K
-
I
S
R
S
L
G
A
S
V
Y
C
V
G
V
L
D
F
E
Q
A
Q
L
E
R
I
A
D
S
--
K
--
E
Q
V
F
P
V
K
G
G
F
Q
A
L
K
G
I
-
I
N
S
I
L
A
Q
S
C
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
37.24
26%
52
- C3 -
3KPT
-
?
A:
[248-348]
-----------------------------------
P
T
T
G
I
I
E
L
T
K
I
D
S
A
N
K
N
K
M
K
G
A
E
F
V
L
K
D
N
N
G
-
K
I
V
V
V
AGKEV
T
G
V
S
D
E
N
G
V
I
K
W
S
N
I
P
Y
G
D
Y
Q
I
F
E
T
K
A
P
T
Y
T
K
EDGTKT
S
Y
Q
L
L
K
D
P
I
D
V
K
I
S
E
N
N
Q
T
V
K
L
T
I
--
E
N
---------------
N
K
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
34.94
18%
-9
* C3 *
1ATZ
-
VWF_HUMAN
A:
[925-1108]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
L
D
V
I
L
L
L
D
G
S
S
S
F
P
------
A
S
Y
F
D
E
M
K
S
F
A
K
A
F
I
S
K
A
N
I
-
G
P
R
L
T
Q
V
S
V
L
Q
Y
G
S
I
--
T
T
I
D
V
P
W
N
V
V
P
E
K
A
H
L
L
S
L
V
D
V
M
Q
R
E
G
G
-
P
S
Q
I
G
D
A
L
G
F
A
V
R
Y
L
T
S
E
-
M
H
G
ARPG
A
S
K
A
V
V
I
L
VTD
V
S
V
-
D
---
S
V
D
A
A
A
D
A
A
-
R
S
N
R
--
V
T
V
F
P
I
G
I
G
D
------------------
R
Y
D
A
A
Q
L
R
I
L
A
G
P
A
G
D
S
N
V
V
K
L
Q
R
I
-
E
D
L
-
P
-
T
M
V
T
L
-
G
N
S
F
L
H
K
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
34.93
23%
61
- C3 -
3KPT
-
?
A:
[6-85]
------------------------------------
K
R
G
A
V
D
L
I
K
T
G
V
N
-
E
K
A
M
A
G
A
V
F
S
L
F
K
K
D
G
T
E
V
K
K
------
E
L
A
T
D
A
N
G
H
I
R
V
Q
G
L
E
Y
G
E
Y
Y
F
Q
E
T
K
A
P
K
---------
G
Y
V
I
D
P
T
K
R
E
F
F
V
K
N
S
G
T
I
N
E
D
G
T
--
I
T
---------------
S
G
T
V
V
K
M
E
V
K
N
N
E
E
P
T
I
D
K
K
I
N
G
K
L
E
A
L
P
I
N
P
L
T
N
Y
N
Y
D
I
K
T
L
I
P
E
D
I
K
E
Y
K
K
Y
V
V
T
D
T
L
D
N
R
L
V
I
Q
G
K
P
I
V
K
I
D
G
A
E
V
N
A
N
V
V
E
V
A
I
E
G
Q
K
V
T
A
T
V
K
D
F
T
K
M
D
G
K
K
E
F
H
L
Q
I
K
S
Q
V
K
E
G
V
P
S
G
S
E
I
L
N
T
A
K
I
H
F
T
-
N
K
N
-
D
V
I
G
E
K
E
S
K
P
V
V
V
I
P
T
T
G
I
I
E
L
T
K
I
D
S
A
N
K
N
K
M
K
G
A
E
F
V
L
K
D
N
N
G
K
I
V
V
V
A
G
K
E
V
T
G
V
S
D
-
E
N
G
--------
V
I
K
W
---
S
N
I
P
Y
G
D
Y
Q
I
F
E
T
K
A
P
T
-
Y
T
K
E
--
D
G
T
K
T
S
Y
Q
L
L
K
D
P
I
D
V
K
-
I
------
S
--
E
N
N
Q
T
V
K
L
T
I
E
N
N
K
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
34.44
16%
-5
- C3 -
1SHU
1
ANTR2_HUMAN
X:
[2-182]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
C
R
R
A
F
D
L
Y
F
V
L
D
K
S
G
S
V
A
N
N
W
I
E
I
Y
N
F
V
Q
Q
L
A
E
R
--------
F
V
-
S
P
E
-
M
R
L
S
F
I
V
F
S
S
Q
---------------------------------------
A
T
I
I
L
P
L
T
G
D
-
R
G
K
--------
I
S
K
G
---
L
E
D
L
K
R
V
S
P
V
-----------
G
--
E
T
Y
I
H
E
G
L
K
L
A
N
E
Q
I
Q
K
-
A
------
G
--
G
L
K
T
S
S
I
I
I
A
L
T
D
G
K
L
D
G
L
V
P
S
Y
A
E
-
K
E
A
-
K
-
I
S
R
S
L
G
A
S
V
Y
C
V
G
V
L
D
F
E
Q
A
Q
L
E
R
I
A
D
S
--
K
--
E
Q
V
F
P
V
K
G
G
F
Q
A
L
K
G
I
-
I
N
S
I
L
A
Q
S
C
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------