@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0763: (2015-12-03 )
MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRAGNFSMEELQEGINYAHARDAKVYVAANMVTHEGNELGAGPWFRELRDMGLDAVIVSDPALIVICATEAPGLEIHLSTQASSTNYETFEFWKEMGLTRVVLAREVTMAELAEIRKRTDVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGQERQSLKGEIPEPFSMSAVDMCMIEHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAYMESPEAFEAIKEDLIDELWKVAQRELATGFYYHTPTENEQLFGARRKIPQYKFVGEVVSFDNAKMEATIRQRNVIMEGDRVEFYGPGFRHFECFIDGLRDAEGNKIDRAPNPMELLTITLPNPVKKGDMIRACKEGLVNLYQNDGTSKTVRA
Atome Classification :
(20 SA)
------------------------.........10........20--........30....---....40...---.-----.....----50........60-......----------..70...-----....-----.80...--------.....90-.......--.-----100-----------.---------.---------------------.---------------.....110---.-.-......120....-----------.----..130.-......140.--......150.....------------------..160..--.....170......--.180.......190.......200.......210.......220.......230...------....240...------....250---.........260--........270..--------......280.......-------290.......300...--....310......--.320.......330.--.....----..340.......-----------------350.......360.......370.......--380.......390.......400.......410.......420......--------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------MSNVKKRPEVLSPAG
T
L
E
K
L
K
--
V
A
I
DYGA
D
A
V
F
VG
G
---
Q
A
Y
GL-RSR---A-----GNF
S
M
----
E
E
L
Q
E
G
INYAHA-R
D
A
K
V
Y
----------
V
A
A
N
M
V
T-----HEGN-----ELGA
G
P
--------
W
F
R
E
L
R
D-MGL
D
A
V
I
--V-----SD------------P---------
A
---------------------
L
---------------
I
V
I
CATE----A-P-
G
L
E
I
H
L
STQASST-----------N----
Y
E
T
F
E
F
-
W
K
EMG
L
T
R
V
V
--
L
A
RE
V
T
M
A
E
L
A
E
I
R
------------------
K
RTD
V
E
I
--
E
A
F
V
H
G
A
M
C
I
SYS
G
--
R
C
V
LSNHMSHRDANRGGCSQS
C
R
W
K
YDLYDMPFG
Q
E
R
Q
S
LKGEIPEPFS
M
S
A
V
D
M
C
M
------
I
E
H
I
P
D
M
I
E
N------G
V
D
S
L
-----
K
IEG
R
M
K
S
I
H
Y
---
V
S
T
V
T
N
C
Y
K
-
A
A
V
--------
D
A
Y
MES
P
E
A
F
E
A
I
K
E
D
-------
L
I
D
E
L
W
K
V
A
Q
R
E
LA
T
G
--
F
Y
Y
HTPTE
N
E
Q
L
F
--
G
A
RRKIP
Q
Y
K
F
V
G
-
E
--
V
VSFD----NA
K
M
E
A
T
I
RQR
N
-----------------
V
IMEGD
R
V
E
F
YGPG
F
R
H
F
E
C
F
I
D
G
LRDAEG--NKIDRAPN
P
M
E
L
L
T
I
TLPNPVKK
G
D
M
I
R
A
C
K
E
G
L
V
N
L
Y
QNDGTSKTVRA--------------
41
Fugue
74.52
18%
-41
- C3 -
4O2X
-
MALE_ECOLI
A:
[5-483]
EG
K
L
V
I
W
I
N
GDKG
Y
N
G
L
A
E
V
G
K
K
F
E
K
D
T
G
I
K
V
T
V
E
H
P
D
K
L
E
E
K
F
P
Q
V
A
A
T
G
D
G
P
D
I
I
F
W
A
H
---
D
R
F
G
G
-
Y
A
Q
---
S
-----
G
L
L
A
E
I
T
P
D
K
A
F
Q
D
K
L
-
Y
P
F
T
-
W
D
A
V
R
Y
NGKLI
A
Y
P
I
A
V
E
A
L
S
L
I
-----
Y
N
K
D
-----
L
L
P
N
P
P
KTWEE
I
P
A
L
D
K
E
L
K
A
-
K
G
K
S
A
L
M
FN
L
-----
Q
E
------------
P
---------
Y
---------------------
F
---------------
T
W
P
L
I
A
A
----
D
-
G
-
G
Y
A
F
K
Y
E
----
N
G
-----------
K
----
Y
D
I
K
D
V
-
G
V
D
N
A
G
A
K
A
G
--
L
T
F
L
V
D
L
I
K
N
K
H
M
N
------------------
A
D
T
D
Y
S
I
A
E
A
A
F
N
K
G
E
T
A
M
T
I
N
G
--
P
W
A
W
S
N
I
D
T
S
K
V
------------
N
Y
G
V
T
V
L
P
------
T
F
K
G
Q
P
S
K
P
F
-
V
G
V
L
S
A
G
I
N
AASPN
K
E
L
A
K
E
F
L
E
N
YLLT
D
E
G
L
E
A
V
-----
N
K
D
K
P
L
G
A
V
A
L
---
K
S
Y
E
E
E
L
A
K
D
P
R
I
--------
A
A
T
M
E
N
A
Q
K
G
E
I
M
P
N
I
-------
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
--
A
A
S
G
R
Q
T
V
D
E
A
L
A
--
A
A
Q
T
N
A
A
--------------------
A
N
L
E
K
I
K
K
L
R
N
-----------------
V
I
T
S
A
W
K
V
I
L
Y
N
D
D
I
H
N
F
T
Y
V
T
D
V
I
V
K
V
V
G
--
Q
I
S
K
A
K
A
H
T
I
T
V
E
A
H
S
T
G
Q
A
L
I
L
S
T
W
K
S
K
A
E
K
Y
C
Q
E
L
Q
Q
N
G
L
T
V
S
I
I
H
E
S-------------
37
Fugue
69.57
14%
-49
- C6 -
1URO
1
DCUP_HUMAN
A:
[10-366]
-------------------------
G
F
P
E
L
K
N
D
T
F
L
R
A
A
W
G
E
E
T
D
--
Y
T
P
------
V
W
C
M
R
---
Q
A
----------------
G
R
Y
L
-----------
P
E
F
R
E
T
-
R
A
A
Q
D
F
----------
F
S
T
C
R
S
P
-----
E
A
C
C
-----
E
L
T
L
Q
P
--------
L
R
R
-----
F
P
L
D
A
A
I
--
I
-----
F
S
------------
D
---------
I
---------------------
L
---------------
V
V
P
Q
A
--------
L
-
G
M
E
V
T
M
V
P
G
K
G
P
S
-----------
F
----
P
E
P
L
R
E
-
E
Q
D
L
E
R
---
L
--
R
D
P
E
V
V
A
S
E
L
G
Y
V
F
------------------
Q
A
I
T
L
T
R
--
Q
R
L
A
G
R
V
P
L
I
G
F
A
G
A
P
W
T
L
M
T
Y
M
V
E
------
G
G
G
S
S
T
M
A
Q
A
K
R
W
L
Y
Q
R
----------
P
Q
A
S
H
Q
L
L
R
I
L
T
D
A
L
------
V
P
Y
L
V
G
Q
V
V
A
------
G
A
Q
A
L
-----
Q
L
F
E
S
H
------------------------------
A
G
H
L
G
P
Q
L
F
N
K
F
A
L
P
-------
Y
I
R
D
V
A
K
Q
V
K
A
R
L
R
E
A
--
G
L
A
P
V
P
---
M
I
I
F
A
K
D
G
H
F
A
L
E
E
L
A
Q
A
G
Y
E
--
V
V
G
L
D
WTVA
P
K
K
A
R
E
C
V
G
K
T
V
-----------------
T
L
Q
G
N
L
D
P
C
A
L
Y
A
S
E
E
E
I
G
Q
L
V
K
Q
M
L
D
D
F
G
--
P
H
---------
R
Y
I
A
N
L
G
H
G
L
Y
P
D
M
D
P
E
H
V
G
A
F
V
D
A
V
H
K
H
S
R
L
L
R
Q
-----------------
36
Fugue
69.13
12%
-41
* C6 *
1B1Y
2
AMYB_HORVU
A:
[1-500]
-----------MKGN
Y
V
Q
V
Y
V
M
L
P
L
D
A
V
S
V
N
N
R
F
E
K
G
D
E
L
R
A
Q
L
R
--
K
L
V
E
A
G
V
D
G
V
M
V
D
V
W--
W
G
L
V
E
-
G
K
G
---
P
-----
K
A
Y
D
W
----
S
A
Y
K
Q
L
F
E
L
V
Q
K
-
A
G
L
K
L
Q
----------
A
I
M
S
F
H
Q
-----
C
G
G
N
VGDA
V
N
I
P
I
P
Q
--------
W
V
R
D
V
G
T
-
R
D
P
D
I
F
Y
--
T
DGHGT
R
N
------------
I
---------
E
---------------------
Y
---------------
L
T
L
G
V
D
N
----
Q
-
P
-
L
F
H
G
R
S
A
V
Q
M
Y
A
D
-----------
Y
----
M
T
S
F
R
E
N
M
K
D
F
L
D
A
G
V
I
--
V
D
I
E
V
G
L
G
P
A
G
E
L
R
YPSYPQSHGWSFPGIGEF
I
C
Y
D
K
Y
L
--
Q
A
D
F
K
A
A
A
A
A
V
-------------
G
H
--
P
E
W
E
F
P
N
D
A
G
Q
Y
N
D
T
P
E
R
T
Q
F
F
R
D
N
G
T
Y
L
S
E
K
G
R
F
F
-
L
A
W
Y
S
N
N
L
------
I
K
H
G
D
R
I
L
D
E
------
A
N
K
V
F
LGYK
V
Q
L
A
I
K
I
A
G
V
H
W
WYK
V
P
--
S
H
A
A
E
-
L
T
A
GYYNLHDR
D
G
Y
R
T
I
A
R
M
L
K
R
H
R
A
S
-------
I
N
F
T
C
A
E
M
R
D
S
E
Q
P
P
D
--
A
M
S
A
P
E
E
L
V
Q
Q
V
L
--
S
A
G
W
R
E
-
G
L
N
V
S
C
-
E
N
A
L
P
R
Y
D
----
P
T
A
Y
N
T
I
L
R
N
A
R
PHGINQSGPPEHKLF
G
F
T
Y
L
R
L
S
N
Q
L
V
E
G
Q
N
Y
V
N
F
K
T
F
V
D
R
M
H
A
N
L
P
RD
P
Y
V
----
D
P
M
A
P
L
P
R
S
G
P
-
E
I
S
I
E
M
I
L
Q
A
A
Q
P
K
I
Q
P
F
P
F
Q
E
H
T
D
L
P
V
G
P
TGGMGGQAEGPTCG
22
HHSearch
64.03
18%
-75
- C5 -
1MZH
-
DEOC_AQUAE
A:
[73-207]
----------------------------------------
V
K
E
A
V
--
E
A
V
R
D
G
A
Q
E
L
D
I
V
W
---
N
L
S
A
F
-
K
S
E
---
K
-----
Y
D
F
V
V
----
E
E
L
K
E
I
F
R
E
T
P
S
-
A
V
H
K
V
I
----------
V
E
T
P
Y
-
L
-----
N
E
E
--------
E
I
K
K
--------
A
V
E
I
C
I
E
-
A
G
A
D
F
I
K
--
T
-----
S
T
------------
G
---------
F
APRGTT
L
E
-------------
E
---------------
V
R
L
I
K
S
S
----
A
K
G
-
R
I
K
V
K
A
S
G
G
I
R
-------------
D
----
L
E
T
A
I
S
-
M
I
E
A
G
A
D
R
I
G
--
T
S
S
G
I
S
I
A
E
E
F
L
K
R
------------------
H
L
I
L
E
H
H
--
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
62.13
13%
-30
- C2 -
2B3Z
1
RIBD_BACSU
A:
[13-371]
-------------------------
M
E
E
Y
Y
M
K
L
A
L
D
L
A
K
Q
G
E
G
-
Q
--
T
E
S
N
P
L
V
G
A
V
V
V
K
D
GQI
V
G
M
G
A
-
H
L
K
---
Y
-----
G
E
A
H
A
----
E
V
H
A
I
H
M
A
G
A
H
A
-
E
G
A
D
I
Y
----------
V
T
L
E
P
C
S
-----
H
Y
G
K
-----
T
---
P
P
--------
C
A
E
L
I
I
N
-
S
G
I
K
R
V
F
--
V
-----
A
---------------------------------------------------------------------------------
M
R
D
P
N
P
L
V
-----------
A
----
G
R
G
I
S
M
-
M
K
E
A
G
I
E
V
R
E
--
G
I
L
A
D
Q
A
E
R
L
N
E
K
F
------------------
L
H
F
M
R
T
G
--
L
P
Y
V
T
L
K
A
A
A
S
L
D
G
--
K
I
A
T
S
T
G
D
S
K
W
I
T
S
----------------------------------
E
A
A
R
Q
D
A
Q
Q
------
Y
R
K
T
H
Q
S
I
L
V
------
G
V
G
T
V
-----
K
A
D
N
P
S
L
T
C
R
L
---
P
N
V
T
K
Q
P
V
R
-
V
I
L
--------
D
T
V
L
S
I
P
E
D
A
K
V
I
C
D
Q
I
A
P
T
W
I
F
T
T
A
R
A
D
E
E
K
K
K
R
L
S
A
F
G
V
N
I
F
T
L
E
T
E
R
I
Q
I
P
--
D
V
L
K
I
L
A
E
E
G
-
I
M
-
S
--
V
Y
V
E
G
----
G
S
A
V
H
G
S
F
V
K
E
G
-----------------
C
F
--
Q
E
I
I
F
Y
F
A
P
------------
K
L
I
G
G
--
T
H
A
P
S
L
I
S
G
E
G
F
Q
S
M
K
D
V
P
L
L
Q
F
T
D
I
T
Q
I
G
R
D
I
K
L
T
A
K
P
T
-----------------------
24
HHSearch
58.98
12%
-95
- C5 -
3R12
3
DEOC_THEMA
A:
[113-244]
---------------------------------------
K
A
H
E
A
I
--
F
A
V
E
S
G
A
D
E
I
D
M
V
I
---
N
V
G
M
L
-
K
A
K
---
E
-----
W
E
Y
V
Y
----
E
D
I
R
S
V
V
E
S
V
K
G
-
K
V
V
K
V
I
----------
I
E
T
C
Y
L
------
D
T
E
-------
E
K
I
-
A
--------
A
C
V
I
S
K
L
-
A
G
A
H
F
V
K
--
T
-----
S
T
------------
G
FGTGGAT
A
-
E
---------------------
D
---------------
V
H
L
M
K
W
I
----
V
-
G
D
E
M
G
V
K
A
S
G
G
I
R
T
-----------------
F
E
D
A
V
K
-
M
I
M
Y
G
A
D
R
I
G
--
T
S
S
G
V
K
I
V
Q
G
G
E
E
R
------------------
Y
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
58.63
11%
-82
- C5 -
2QIW
8
?
A:
[20-202]
------------------------------
K
L
L
V
L
P
T
V
W
D
T
W
S
A
G
--
L
V
E
E
A
G
F
S
G
L
T
I
G
S
---
H
P
V
A
D
-
A
T
G
SSD
G
-----
E
N
M
N
F
----
A
D
Y
M
A
V
V
K
K
I
T
S
A
V
S
I
P
V
S
----------
V
D
V
E
S
G
Y
------
G
L
--------
S
P
A
D
--------
L
I
A
Q
I
L
E
-
A
G
A
V
G
I
N
--
V
-----
E
D
------------
V
---------
V
---------------------
H
SEGKRVRE
A
Q
E
H
A
D
Y
I
A
A
A
R
Q
A
A
D
V
A
G
-
V
-
D
V
V
I
N
G
R
T
D
A
V
K
L
GADVFED
P
M
V
E
A
----
I
K
R
I
K
L
-
M
E
Q
A
G
A
R
S
V
Y
--
P
V
G
L
S
T
A
E
Q
V
E
R
L
V
------------------
D
A
V
S
V
P
V
--
N
I
T
A
H
P
V
D
G
H
G
A
G
D
--
L
A
T
L
A
G
L
G
V
R
R
V
T
F
G
P
L
W
Q
K
W
L
A
A
T
S
A
Q
Q
L
K
G
W
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
57.74
10%
-96
- C5 -
1WA3
3
?
A:
[71-183]
--------------------------------------
T
S
V
E
Q
C
R
--
K
A
V
E
S
G
A
E
F
I
V
S
P
H
---
L
D
----------------------------
E
E
I
S
Q
F
C
K
E
-
K
G
V
F
Y
M
----------
P
G
V
M
T
--------
P
T
E
--------------------
L
V
K
A
M
K
-
L
G
H
T
I
L
K
--
L
-----
F
P
GEVVG-------
P
---------
Q
---------------------
F
---------------
V
K
A
M
K
G
P
----
F
-
P
-
N
V
K
F
V
P
T
G
G
V
N
L
------------------
D
N
V
C
E
-
W
F
K
A
G
V
L
A
V
G
--
V
G
S
A
L
V
K
G
T
P
D
E
V
R
------------------
E
K
A
K
A
F
V
--
E
K
I
R
G
C
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
56.46
13%
-91
- C5 -
1XG4
2
PRPB_ECOLI
A:
[20-201]
---------------------------------
Q
I
V
G
T
I
N
A
N
H
A
L
--
L
A
Q
R
A
G
Y
Q
A
I
Y
L
S
G
---
G
G
V
A
A
G
S
L
G
LPD
L
-----
G
I
S
T
L
----
D
D
V
L
T
D
I
R
R
I
T
D
V
C
S
L
P
L
L
----------
V
D
A
D
I
G
F
------
G
S
S
-----
A
F
N
V
A
R
--------
T
V
K
S
M
I
K
-
A
G
A
A
G
L
H
--
I
-----
E
D
------------
Q
---------
V
GAKRSGHRPN
K
A
I
V
S
K
E
E
M
V
D
R
---------------
I
R
A
A
V
D
A
KT--
D
-
P
-
D
F
V
I
M
A
R
T
D
A
L
A
V
E----------
G
L
D
A
A
I
E
R
A
Q
A
-
Y
V
E
A
G
A
E
M
L
F
--
P
E
A
I
T
E
L
A
M
Y
R
Q
F
A
------------------
D
A
V
Q
V
P
I
--
L
A
N
I
T
E
F
G
A
T
P
L
F
T
--
T
D
E
L
R
S
A
H
V
A
M
A
L
Y
P
L
S
A
F
R
A
M
N
R
A
A
E
H
V
Y
N
V
L
R
Q
E
G
T
Q
K
S
V
I
D
T
M
Q
T
R
N
E
L
Y
E
S
I
N
------
Y
Y
Q
Y
E
E
K
L
D
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
54.60
10%
-79
* C5 *
3NGJ
3
?
A:
[97-224]
---------------------------------------
K
A
Y
E
T
K
--
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
---
N
I
G
M
V
-
K
A
K
---
K
-----
Y
D
D
V
E
----
K
D
V
K
A
V
V
D
A
S
G
K
-
A
L
T
K
V
I
----------
I
E
C
C
Y
L
------
T
N
E
--------
E
K
V
E
--------
V
C
K
R
C
V
A
-
A
G
A
E
Y
V
K
--
T
-----
S
T
------------
G
FGTHGAT
P
-
E
---------------------
D
---------------
V
K
L
M
K
D
T
----
V
-
G
D
K
A
L
V
K
A
A
G
G
--
I
R
-----------
T
----
F
D
D
A
M
K
-
M
I
N
N
G
A
S
R
I
G
--
A
S
A
G
I
A
I
L
N
G
I
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
54.59
13%
-85
- C5 -
3TSM
1
TRPC_BRUA2
A:
[130-253]
--------------------------------------
F
D
P
Y
Q
V
Y
--
E
A
R
S
W
G
A
D
C
I
L
I
I
M
---
A
S
V
D
------------------
D
----
D
L
A
K
E
L
E
D
T
A
F
A
-
L
G
M
D
A
L
----------
I
E
V
H
D
--------
E
A
E
-----
M
E
---------------
R
A
L
K
-
L
S
S
R
L
L
G
--
V
-----
N
N
------------
R
NLRSFEVNL
A
---------------------
V
---------------
S
E
R
L
A
K
M
----
A
-
P
S
D
R
L
L
V
G
E
S
G
I
F
-------------
T
----
H
E
D
C
L
R
-
L
E
K
S
G
I
G
T
F
L
--
I
G
E
S
L
M
R
Q
H
D
V
A
A
A
------------------
T
R
A
L
L
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
53.32
11%
-86
- C5 -
1I4N
1
TRPC_THEMA
A:
[112-234]
---------------------------------------
D
T
V
Q
V
K
--
L
A
S
S
V
G
A
D
A
I
L
I
I
A
---
R
I
L
T
------------------
A
----
E
Q
I
K
E
I
Y
E
A
A
E
E
-
L
G
M
D
S
L
----------
V
E
V
H
S
--------
R
E
D
-----
L
E
---------------
K
V
F
S
V
I
R
P
K
I
I
G
--
I
-----
N
T
------------
R
---------
D
LDTFEIKKN------------
V
---------------
L
W
E
L
L
P
L
----
V
-
P
D
D
T
V
V
V
A
E
S
G
I
--
K
-----------
D
----
P
R
E
L
K
D
-
L
R
-
G
K
V
N
A
V
L
--
V
G
T
S
I
M
K
A
E
N
P
R
R
F
------------------
L
E
E
M
R
A
W
--
S
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
52.73
13%
-92
- C5 -
3JR2
8
?
A:
[74-198]
-----------------------------------------
I
L
S
R
--
M
A
F
E
A
G
A
D
W
I
T
V
S
A
---
A
A
H
I
-----------------------
A
T
I
A
A
C
K
K
V
A
D
E
-
L
N
G
E
I
Q
----------
I
E
I
Y
G
N
W
-----
T
M
Q
D
--------------------
A
K
A
W
V
D
-
L
G
I
T
Q
A
I
--
Y
-----
H
R
S
R
D
A
E
L
A
GIGWT
T
---------
D
---------------------
D
---------------
L
D
K
M
R
Q
L
----
S
A
L
-
G
I
E
L
S
I
T
G
G
I
V
------------------
P
E
D
I
Y
L
-
F
E
G
I
K
T
K
T
F
I
--
A
G
R
A
L
A
G
A
E
G
Q
Q
T
A
------------------
A
A
L
R
E
Q
I
--
D
R
F
W
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
51.83
12%
-81
- C5 -
3QJA
1
TRPC_MYCTU
A:
[124-246]
---------------------------------------
Q
P
Y
Q
I
H
--
E
A
R
A
H
G
A
D
M
L
L
L
I
V
---
A
A
L
------------------
E
Q
----
S
V
L
V
S
M
L
D
R
T
E
S
-
L
G
M
T
A
L
----------
V
E
V
H
--------
T
E
Q
E
-----
A
D
---------------
R
A
L
K
-
A
G
A
K
V
I
G
--
V
-----
N
A
------------
R
---------
D
LMTLDVDRD------------
C
---------------
F
A
R
I
A
P
G
----
L
-
P
S
S
V
I
R
I
A
E
S
G
V
R
-------------
G
----
T
A
D
L
L
A
-
Y
A
G
A
G
A
D
A
V
L
--
V
G
E
G
L
V
T
S
G
D
P
R
A
A
------------------
V
A
D
L
V
T
A
--
G
T
H
P
S
C
P
K
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
50.71
33%
-54
- C7 -
4HE6
2
?
A:
[7-86]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
A
G
-
L
--
V
L
G
Y
D
----
P
E
T
G
I
A
T
V
Q
Q
R
N
-----------------
H
F
R
P
G
D
E
V
E
F
F
G
P
E
I
E
N
F
T
Q
V
I
E
K
I
W
D
E
D
G
--
N
E
L
D
A
A
R
H
P
L
Q
I
V
K
F
K
V
K
R
P
L
F
P
Y
N
M
M
R
K
E
N
--------------------------------
16
HHSearch
50.41
13%
-80
- C5 -
1UB3
1
DEOC_THET8
A:
[73-210]
---------------------------------------
K
A
L
E
A
A
--
L
A
C
A
R
G
A
D
E
V
D
M
V
L
---
H
L
G
R
A
-
K
A
G
---
D
-----
L
D
Y
L
E
----
A
E
V
R
A
V
R
E
A
V
P
Q
-
A
V
L
K
V
I
----------
L
E
T
G
Y
F
------
S
P
E
E
--------
I
A
R
--------
L
A
E
A
A
I
R
-
G
G
A
D
F
L
K
--
T
-----
S
T
GFGPRGAS----
L
---------
E
---------------------
D
---------------
V
A
L
L
V
R
V
----
A
-
Q
G
R
A
Q
V
K
A
A
G
G
I
R
-------------
D
----
R
E
T
A
L
R
-
M
L
K
A
G
A
S
R
L
G
T
S
S
G
V
A
L
V
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
50.27
34%
-58
- C7 -
4HE5
1
?
A:
[7-79]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
A
G
-
L
--
V
L
G
Y
D
----
P
E
T
G
I
A
T
V
Q
Q
R
N
-----------------
H
F
R
P
G
D
E
V
E
F
F
G
P
E
I
E
N
F
T
Q
V
I
E
K
I
W
D
E
D
G
--
N
E
L
D
A
A
R
H
P
L
Q
I
V
K
F
K
V
K
R
P
L
F
P
Y
N
M
M
R
K
----------------------------------
34
Fugue
49.96
30%
-48
* C7 *
4HE6
2
?
A:
[1-89]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
K
T
T
R
E
F
A
G
-
L
--
V
L
G
Y
D
----
P
E
T
G
I
A
T
V
Q
Q
R
N
-----------------
H
F
R
P
G
D
E
V
E
F
F
G
P
E
I
E
N
F
T
Q
V
I
E
K
I
W
D
E
D
G
--
N
E
L
D
A
A
R
H
P
L
Q
I
V
K
F
K
V
K
R
P
L
F
P
Y
N
M
M
R
K
E
N
--------------------------------
14
HHSearch
48.31
15%
-78
- C5 -
3KTS
1
?
A:
[7-101]
----------------------------
F
S
N
Q
S
I
I
P
A
A
H
N
Q
K
D
M
E
--
K
I
L
E
L
D
L
T
Y
M
V
M
L
E
---
T
H
V
------------------------
A
Q
L
K
A
L
V
K
Y
A
Q
A
-
G
G
K
K
V
L
----------
L
H
A
D
L
V
N
-----
G
L
K
N
-----
D
D
Y
A
I
D
--------
F
L
C
T
E
---
I
C
P
D
G
I
I
--
S
-----
T
R
------------
G
---------
N
---------------------
A
---------------
I
M
K
A
K
Q
H
----
K
-
M
-
L
A
I
Q
R
L
F
M
I
D
S
S
A
-----------
Y
----
N
K
G
V
A
L
-
I
Q
K
V
Q
P
D
C
I
E
--
L
L
P
G
I
I
P
E
Q
V
Q
K
M
T
------------------
Q
K
L
H
I
P
V
--
I
A
G
G
L
I
E
T
S
E
Q
V
N
Q
--
V
I
A
S
G
A
I
A
V
T
T
S
N
K
H
L
W
E
G
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
48.26
15%
-56
- C5 -
1YDO
1
HMGCL_BACSU
A:
[76-179]
--------------------------------
T
Y
A
A
L
V
P
N
Q
R
G
L
E
--
N
A
L
E
G
G
I
N
E
A
C
V
F
M
---
S
A
S
E
T
-
H
N
R
---
K
N
INKS
T
S
E
S
L
----
H
I
L
K
Q
V
N
N
D
A
Q
K
-
A
N
L
T
T
R
----------
A
Y
L
S
T
V
F
GCPYE
K
D
V
P
-----
I
E
Q
V
I
R
--------
L
S
E
A
L
F
E
-
F
G
I
S
E
L
S
--
L
-----
G
D
------------
T
---------
I
---------------------
G
---------------
A
A
N
P
A
Q
V
----
E
-
T
-
V
L
E
A
L
L
A
R
F
P
A
N
Q
-----------
I
----
A
L
H
F
H
D
-
T
R
G
T
A
L
A
N
M
V
--
T
A
L
Q
M
G
I
T
V
F
D
G
S
A
------------------
G
G
L
G
G
C
P
--
Y
A
P
G
S
S
G
N
A
A
T
E
D
I
--
V
Y
M
L
E
Q
M
D
I
K
T
N
V
K
L
E
K
L
L
S
A
A
K
W
I
E
E
K
M
G
K
P
L
P
S
R
N
L
Q
V
F
K
S
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