@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0773: (2015-12-03 )
MKFYLVRHGKTQWNLEGRFQGANGDSPLLEEAIEELEELGQYLSSIHFDAVYSSDLGRARDTVNILNDANSCPKEIHYTPQLREWALGTLEGCKIATMQAIYPRQMTAFYQNPLQFKHDMFGAESLYQTTHRVESFLRSLASKNYDKVLIVGHGANLTASIRSLLGYQYGSLHYKDKLDNASLTIIETHDFKDFNCLTWNDKSYLRQEVKMTH
Atome Classification :
(20 SA)
.........10........20........30........40....--....50........60...-.....70---.----........80........90....-----....100-..--------...-.-...--110------------------------.------------------------.----------------------.....120..---------.....130..--.....140.---------------------------..-..-..150.......160.....---..----170..-.-------...-...180.......190.--------..--.....200.......210.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
F
Y
L
V
RHG
K
T
Q
W
N
L
E
G
R
F
QGANGD
S
P
L
L
E
E
A
I
E
E
L
E
E
L
G
Q
Y
L
S
S
--
I
HFD
A
V
YSSDLGRAR
D
T
V
N
-ILNDAN----S----C
P
K
EIHY
T
P
Q
L
R
E
W
A
LGTLEG
C
K
I
-----
A
T
M
QA---I
Y
--------
P
R
Q
-
M
-
T
A
F
--YQN------------------------
P
------------------------
L
----------------------
Q
F
K
H
DMF
G
A
E
---------
S
L
Y
Q
T
T
H
R
V
E
--
S
F
L
R
S
L
A
SK---------------------------NY-
D
K
-
V
L
I
V
GHGA
N
L
T
A
S
I
R
S
L
L
G
Y---QY----G--S
L
-
H
-------
Y
KD-KLDNA
S
L
T
I
I
E
THD-FK--------DF--N
C
L
TWN
D
K
S
Y
L
R
Q
E
VKMTH
3
PsiBlast_PDB
87.08
29%
-72
- C2 -
1EBB
8
?
A:
[4-201]
--
L
Y
L
T
R
H
G
E
T
K
W
N
V
E
R
R
M
Q
G
W
Q
-
D
S
P
L
T
E
K
G
R
Q
D
A
M
R
L
G
K
R
L
E
A
--
V
E
L
A
A
I
Y
T
S
T
S
G
R
A
L
E
T
A
E
-
I
V
R
G
G
R
----
L
----
I
P
--
I
Y
Q
D
E
R
L
R
E
I
H
L
G
D
W
E
G
K
T
H
-----
D
E
I
R
Q
---
M
D
--------
P
I
A
-
F
-
D
H
F
--
W
Q
A
------------------------
P
------------------------
H
----------------------
L
Y
A
P
Q
R
--
G
E
---------
R
F
C
D
V
Q
Q
R
A
L
--
E
A
V
Q
S
I
V
D
R
---------------------------
H
E
G
E
T
-
V
L
I
V
T
H
G
V
V
L
K
T
L
M
A
A
F
K
D
T
---
P
L
----
D
--
H
L
-
W
-------
S
P
P
-
Y
M
Y
G
T
S
V
T
I
I
E
V
-
D
-
G
G
--------
T
F
--
H
V
A
V
E
G
D
V
S
H
I
E
-------
2
PsiBlast_PDB
85.58
30%
-65
- C2 -
1H2F
2
?
A:
[4-205]
--
L
Y
L
T
R
H
G
E
T
K
W
N
V
E
R
R
M
Q
G
W
Q
-
D
S
P
L
T
E
K
G
R
Q
D
A
M
R
L
G
K
R
L
E
A
--
V
E
L
A
A
I
Y
T
S
T
S
G
R
A
L
E
T
A
E
-
I
V
R
G
G
R
----
L
----
I
P
--
I
Y
Q
D
E
R
L
R
E
I
H
L
G
D
W
E
G
K
T
H
-----
D
E
I
R
Q
---
M
D
--------
P
I
A
-
F
-
D
H
F
--
W
Q
A
------------------------
P
------------------------
H
----------------------
L
Y
A
P
Q
R
--
G
E
---------
R
F
C
D
V
Q
Q
R
A
L
--
E
A
V
Q
S
I
V
D
R
---------------------------
H
E
G
E
T
-
V
L
I
V
T
H
G
V
V
L
K
T
L
M
A
A
F
K
D
T
---
P
L
----
D
--
H
L
-
W
-------
S
P
P
-
Y
M
Y
G
T
S
V
T
I
I
E
V
-
D
-
G
G
--------
T
F
--
H
V
A
V
E
G
D
V
S
H
I
-
E
E
V
K
E
V
-
68
HHSearch
85.32
30%
-70
- C2 -
1H2E
3
?
A:
[2-206]
T
T
L
Y
L
T
R
H
G
E
T
K
W
N
V
E
R
R
M
Q
G
W
-
Q
D
S
P
L
T
E
K
G
R
Q
D
A
M
R
L
G
K
R
L
E
A
--
V
E
L
A
A
I
Y
T
S
T
S
G
R
A
L
E
T
A
E
-
I
V
R
G
G
R
----
L
----
I
P
--
I
Y
Q
D
E
R
L
R
E
I
H
L
G
D
W
E
G
K
T
H
-----
D
E
I
R
Q
---
M
D
--------
P
I
A
-
F
-
D
H
F
--
W
Q
A
------------------------
P
------------------------
H
----------------------
L
Y
A
P
--
Q
R
G
E
---------
R
F
C
D
V
Q
Q
R
A
L
--
E
A
V
Q
S
I
V
D
R
H
--------------------------
E
G
-
E
T
-
V
L
I
V
T
H
G
V
V
L
K
T
L
M
A
A
F
K
D
T
---
P
L
----
D
--
H
L
---------
W
S
P
P
Y
M
Y
G
T
S
V
T
I
I
E
V
D
G
--
G
--------
T
F
--
H
V
A
V
E
G
D
V
S
H
I
E
E
V
K
E
V
--
1
PsiBlast_PDB
85.31
30%
-67
* C2 *
1H2E
3
?
A:
[4-205]
--
L
Y
L
T
R
H
G
E
T
K
W
N
V
E
R
R
M
Q
G
W
Q
-
D
S
P
L
T
E
K
G
R
Q
D
A
M
R
L
G
K
R
L
E
A
--
V
E
L
A
A
I
Y
T
S
T
S
G
R
A
L
E
T
A
E
-
I
V
R
G
G
R
----
L
----
I
P
--
I
Y
Q
D
E
R
L
R
E
I
H
L
G
D
W
E
G
K
T
H
-----
D
E
I
R
Q
---
M
D
--------
P
I
A
-
F
-
D
H
F
--
W
Q
A
------------------------
P
------------------------
H
----------------------
L
Y
A
P
Q
R
--
G
E
---------
R
F
C
D
V
Q
Q
R
A
L
--
E
A
V
Q
S
I
V
D
R
---------------------------
H
E
G
E
T
-
V
L
I
V
T
H
G
V
V
L
K
T
L
M
A
A
F
K
D
T
---
P
L
----
D
--
H
L
-
W
-------
S
P
P
-
Y
M
Y
G
T
S
V
T
I
I
E
V
-
D
-
G
G
--------
T
F
--
H
V
A
V
E
G
D
V
S
H
I
-
E
E
V
K
E
V
-
70
HHSearch
84.55
31%
-64
- C2 -
3R7A
1
?
A:
[14-232]
V
T
L
Y
V
T
R
H
G
K
T
I
L
N
T
N
H
R
A
Q
G
W
-
A
D
S
P
L
V
E
K
G
V
E
V
A
T
N
L
G
T
G
L
K
D
--
I
H
F
M
N
A
Y
S
S
D
S
G
R
A
I
E
T
A
N
-
L
V
L
K
Y
S
EQS-
K
----
L
K
--
L
E
Q
R
K
K
L
R
E
L
N
F
G
I
F
E
G
E
K
L
-----
D
N
M
W
D
---
A
V
G
K
A
A
GVTS
P
E
E
-
L
-
L
K
F
--
S
I
Q
E
V
I
D
L
I
------------------
R
------------------------
A
----------------------
A
D
P
T
--
K
Q
A
E
---------
D
W
E
L
F
S
T
R
I
K
--
A
E
I
D
K
I
S
E
E
A
A
K
D
-----------------------
G
G
-
G
N
-
V
L
V
V
V
H
G
L
L
I
T
T
L
I
E
M
L
D
S
S
---
K
-------------------
T
K
L
-
G
V
E
N
A
S
V
T
K
I
V
Y
Q
D
--
G
--------
I
Y
--
T
V
E
S
V
G
D
M
S
Y
V
A
K
G
K
E
---
4
PsiBlast_PDB
81.67
28%
-68
- C2 -
4IJ5
4
PSPA_HYDTT
A:
[2-189]
V
K
L
I
L
V
R
H
A
E
S
E
W
N
P
V
G
R
Y
Q
G
L
L
-
D
P
D
L
S
E
R
G
K
K
Q
A
K
L
L
A
Q
E
L
S
R
--
E
H
L
D
V
I
Y
S
S
P
L
K
R
T
Y
L
T
A
L
-
E
I
A
E
A
K
----
N
----
L
--
E
V
I
K
E
D
R
I
I
E
I
D
H
G
M
W
S
G
M
L
V
-----
E
E
V
M
E
---
K
Y
--------
P
E
D
-
F
-
R
R
W
--
V
E
E
------------------------
P
------------------------------------------------
H
K
V
E
F
Q
G
G
E
---------
S
L
A
S
V
Y
N
R
V
K
--
G
F
L
E
E
V
R
K
R
---------------------------
H
W
-
N
Q
T
V
V
V
V
S
H
T
V
P
M
R
A
M
Y
C
A
L
L
G
V
---
D
L
----
S
--
K
F
---------
W
S
F
-
G
C
D
N
A
S
Y
S
V
I
H
M
E
E
-
R
R
--------
N
V
--
I
L
K
L
N
I
T
C
H
L
G
E
F
Y
V
E
A
H
K
82
HHSearch
80.94
26%
-64
- C2 -
3D8H
-
?
A:
[21-248]
Y
K
L
T
L
I
R
H
G
E
S
E
W
N
K
E
N
R
F
T
G
W
-
T
D
V
S
L
S
E
Q
G
V
S
E
A
I
E
A
G
R
M
L
L
E
K
G
F
K
F
D
V
V
Y
T
S
V
L
K
R
A
I
M
T
T
W
-
T
V
L
K
E
L
----
G
NIN-
C
P
--
I
I
N
H
W
R
L
N
E
R
H
Y
G
A
L
Q
G
L
N
K
-----
S
E
T
A
S
---
K
F
--------
G
E
D
Q
V
-
K
I
W
--
R
R
S
FDVP
P
P
V
L
E
KSDPRWPGNELIYKG
I
------------------------
C
----------------------
P
S
C
L
--
P
T
T
E
---------
C
L
K
D
T
V
E
R
V
K
--
P
Y
F
E
D
V
I
A
P
S
I
M
------------------------
S
G
-
K
S
-
V
L
V
S
A
H
G
N
S
L
R
A
L
L
Y
L
L
E
G
M
---
T
P
----
E
--
Q
I
---------
L
E
V
-
N
I
P
T
A
C
P
L
V
L
E
L
D
D
-
Y
L
--------
K
V
--
T
K
K
Y
Y
L
I
------------
5
PsiBlast_PDB
80.11
27%
-69
- C2 -
4IJ6
4
PSPA_HYDTT
A:
[2-189]
V
K
L
I
L
V
R
A
A
E
S
E
W
N
P
V
G
R
Y
Q
G
L
L
-
D
P
D
L
S
E
R
G
K
K
Q
A
K
L
L
A
Q
E
L
S
R
--
E
H
L
D
V
I
Y
S
S
P
L
K
R
T
Y
L
T
A
L
-
E
I
A
E
A
K
----
N
----
L
--
E
V
I
K
E
D
R
I
I
E
I
D
H
G
M
W
S
G
M
L
V
-----
E
E
V
M
E
---
K
Y
--------
P
E
D
-
F
-
R
R
W
--
V
E
E
------------------------
P
------------------------------------------------
H
K
V
E
F
Q
G
G
E
---------
S
L
A
S
V
Y
N
R
V
K
--
G
F
L
E
E
V
R
K
R
---------------------------
H
W
-
N
Q
T
V
V
V
V
S
H
T
V
P
M
R
A
M
Y
C
A
L
L
G
V
---
D
L
----
S
--
K
F
---------
W
S
F
-
G
C
D
N
A
S
Y
S
V
I
H
M
E
E
-
R
R
--------
N
V
--
I
L
K
L
N
I
T
C
H
L
G
E
F
Y
V
E
A
S
-
10
PsiBlast_PDB
79.23
31%
-65
- C2 -
3R7A
1
?
A:
[14-214]
V
T
L
Y
V
T
R
H
G
K
T
I
L
N
T
N
H
R
A
Q
G
W
-
A
D
S
P
L
V
E
K
G
V
E
V
A
T
N
L
G
T
G
L
K
D
--
I
H
F
M
N
A
Y
S
S
D
S
G
R
A
I
E
T
A
N
L
V
L
K
Y
S
E
----
Q
----
S
K
L
K
L
E
Q
R
K
K
L
R
E
L
N
F
G
I
F
E
G
E
K
L
D
N
M
W
D
A
V
G
K
A
A
GV
T
S
--------
P
E
E
-
L
-
L
K
F
-----------------------------
S
------------------------
I
----------------------
Q
E
V
I
D
L
I
R
A
A
DPTKQAED
W
E
L
F
S
T
R
I
K
A
E
I
D
K
I
S
E
E
A
A
K
D
---------------------------
G
G
-
G
N
-
V
L
V
V
V
H
G
L
L
I
T
T
L
I
E
M
L
------------
D
--
S
S
-
K
-------
T
K
L
-
G
V
E
N
A
S
V
T
K
I
V
Y
Q
D
-
G
I
--------
Y
T
--
V
E
S
V
G
D
M
S
Y
V
A
K
G
K
E
----
74
HHSearch
78.06
26%
-64
- C2 -
1FZT
-
PMGY_SCHPO
A:
[8-210]
N
L
L
V
L
T
R
H
G
E
S
E
W
N
K
L
N
L
F
T
G
W
-
K
D
P
A
L
S
E
T
G
I
K
E
A
K
L
G
G
E
R
L
K
S
R
G
Y
K
F
D
I
A
F
T
S
A
L
Q
R
A
Q
K
T
C
Q
-
I
I
L
E
E
V
----
G
EPN-
L
E
--
T
I
K
S
E
K
L
N
E
R
Y
Y
G
D
L
Q
G
L
N
K
-----
D
D
A
R
K
---
K
W
--------
G
A
E
Q
V
-
Q
I
W
---
R
R
------------------------
S
------------------------
Y
----------------------
D
I
A
P
--
P
N
G
E
---------
S
L
K
D
T
A
E
R
V
L
--
P
Y
Y
K
S
T
I
V
P
H
I
L
------------------------
K
G
-
E
K
-
V
L
I
A
A
H
G
N
S
L
R
A
L
I
M
D
L
E
G
L
---
T
G
----
D
--
Q
I
---------
V
K
R
-
E
L
A
T
G
V
P
I
V
Y
H
L
D
K
-
D
G
--------
K
Y
--
V
S
K
E
L
I
D
N
-----------
71
HHSearch
76.45
25%
-58
- C2 -
3DCY
1
TIGAR_HUMAN
A:
[9-269]
F
A
L
T
V
V
R
H
G
E
T
R
F
N
K
E
K
I
I
Q
G
Q
G
V
D
E
P
L
S
E
T
G
F
K
Q
A
A
A
A
G
I
F
L
N
N
--
V
K
F
T
H
A
F
S
S
D
L
M
R
T
K
Q
T
M
H
-
G
I
L
E
R
S
----
K
FCKD
M
T
--
V
K
Y
D
S
R
L
R
E
R
K
Y
G
V
V
E
G
K
A
L
-----
S
E
L
R
A
---
M
A
--------
K
A
A
-
R
-------
E
E
------------------------
C
------------------------
P
----------------------
V
F
T
P
--
P
G
G
E
---------
T
L
D
Q
V
K
M
R
G
I
--
D
F
F
E
F
L
C
Q
L
I
L
K
E
A
D
Q
KN
C
L
E
T
S
L
A
E
I
FPLIPG---
L
A
-
A
S
-
V
L
V
V
S
H
G
A
Y
M
R
S
L
F
D
Y
F
L
T
D
---
L
K
----
C
--
S
L
-
P
ATLS
R
S
E
L
M
S
-
V
T
P
N
T
G
M
S
L
F
I
I
N
F
E
E
G
RE
V
-----
K
P
T
V
Q
C
I
C
M
N
L
Q
D
H
L
N
-------
77
HHSearch
76.19
28%
-60
- C2 -
3GP3
3
GPMA_BURP1
A:
[10-236]
Y
K
L
V
L
I
R
H
G
E
S
T
W
N
K
E
N
R
F
T
G
W
-
V
D
V
D
L
T
E
Q
G
N
R
E
A
R
Q
A
G
Q
L
L
K
E
A
G
Y
T
F
D
I
A
Y
T
S
V
L
K
R
A
I
R
T
L
W
-
H
V
Q
D
Q
M
----
D
LMY-
V
P
--
V
V
H
S
W
R
L
N
E
R
H
Y
G
A
L
S
G
L
N
K
-----
A
E
T
A
A
---
K
Y
--------
G
D
E
Q
V
-
L
V
W
--
R
R
S
YDTPPPALEPGDERAPYAD-----
P
------------------------
R
YAKVP-----------------
R
E
Q
L
--
P
L
T
E
---------
C
L
K
D
T
V
A
R
V
L
--
P
L
W
N
E
S
I
A
P
A
V
K
------------------------
A
G
-
K
Q
-
V
L
I
A
A
H
G
N
S
L
R
A
L
I
K
Y
L
D
G
I
---
S
D
----
A
--
D
I
---------
V
G
L
-
N
I
P
N
G
V
P
L
V
Y
E
L
D
E
--
S
--------
L
T
--
P
I
R
H
Y
Y
L
G
S
----------
80
HHSearch
75.99
25%
-60
- C2 -
3KKK
-
?
A:
[4-231]
Y
T
L
V
L
L
R
H
G
E
S
T
W
N
K
E
N
K
F
T
G
W
-
T
D
V
P
L
S
E
K
G
E
E
E
A
I
A
A
G
K
Y
L
K
E
K
N
F
K
F
D
V
V
Y
T
S
V
L
K
R
A
I
C
T
A
W
-
N
V
L
K
T
A
DLL-
H
----
V
P
--
V
V
K
T
W
R
L
N
E
R
H
C
G
S
L
Q
G
L
N
K
-----
S
E
T
A
K
---
K
Y
--------
G
E
E
-
Q
V
K
I
W
--
R
R
S
------------------------
Y
DIP
P
P
K
L
D
KEDNRWPGHNVVYKNV
P
----------------------
K
D
A
L
--
P
F
T
E
---------
C
L
K
D
T
V
E
R
V
L
--
P
F
W
F
D
H
I
A
P
D
I
L
------------------------
A
N
-
K
K
-
V
M
V
A
A
H
G
N
S
L
R
G
L
V
K
H
L
D
N
L
---
S
E
----
A
--
D
V
---------
L
E
L
-
N
I
P
T
G
V
P
L
V
Y
E
L
D
E
-
N
L
--------
K
P
--
I
K
H
Y
Y
L
L
------------
69
HHSearch
75.56
27%
-66
- C2 -
3E9C
2
TIGRB_DANRE
A:
[4-250]
F
A
L
T
I
V
R
H
G
E
T
-------------
D
T
P
L
S
D
T
G
H
Q
Q
A
A
A
A
G
R
Y
L
K
D
--
L
H
F
T
N
V
F
V
S
N
L
Q
R
A
I
Q
T
A
E
-
I
I
L
G
N
N
LHSS
A
----
T
E
--
M
I
L
D
P
L
L
R
E
R
G
F
-----------------------------------------------------------------------------------------------------------------------------
G
E
---------
T
L
E
Q
V
K
T
R
F
K
--
M
F
L
K
S
L
F
Q
R
M
F
E
E
HGSALSSADQPVIAGLADDGAQN
V
P
-
V
H
-
A
L
M
V
S
H
G
A
F
I
R
I
S
V
R
H
L
V
E
D
---
L
Q
C
C
L
P
A
GL
K
M
N
Q
-------
V
F
S
-
P
C
P
N
T
G
I
S
R
F
I
F
T
I
-
H
R
E
ES
V
L
R
A
T
R
I
--
Q
G
V
F
I
N
R
K
D
H
L
--------
91
HHSearch
75.38
34%
-71
- C2 -
1V37
1
?
A:
[1-171]
M
E
L
W
L
V
R
H
G
E
T
L
W
N
R
E
G
R
L
L
G
W
-
T
D
L
P
L
T
A
E
G
E
A
Q
A
R
R
L
K
G
A
L
P
S
-----
L
P
A
F
S
S
D
L
L
R
A
R
R
T
A
E
-
L
A
G
------------
F
S
--
P
R
L
Y
P
E
L
R
E
I
H
F
G
A
L
E
G
A
L
W
-----
E
T
L
D
P
---
R
Y
--------
K
E
A
-
L
-
L
R
F
------------------------------------------------------
Q
----------------------
G
F
H
P
--
P
G
G
E
---------
S
L
S
A
F
Q
E
R
V
F
--
R
F
L
E
G
L
K
--------------------------------
A
P
-
A
V
L
F
T
H
G
G
V
V
R
A
V
L
R
A
L
G
E
D
GLV
P
P
----
G
--
S
A
---------
V
A
V
-
D
W
P
R
R
V
L
V
R
L
A
L
D
-----------------------------------
75
HHSearch
72.33
22%
-46
- C2 -
1QHF
3
PMG1_YEAST
A:
[1-234]
P
K
L
V
L
V
R
H
G
Q
S
E
W
N
E
K
N
L
F
T
G
W
-
V
D
V
K
L
S
A
K
G
Q
Q
E
A
A
R
A
G
E
L
L
K
E
K
K
V
Y
P
D
V
L
Y
T
S
K
L
S
R
A
I
Q
T
A
N
-
I
A
L
E
K
A
----
D
RLW-
I
P
--
V
N
R
S
W
R
L
N
E
R
H
Y
G
D
L
Q
G
K
D
K
-----
A
E
T
L
K
---
K
F
--------
G
E
E
-
K
F
N
T
Y
--
R
R
S
FDVPPPPIDASSPFSQKGDERYKY
V
------------------------
D
----------------------
P
N
V
L
--
P
E
T
E
---------
S
L
A
L
V
I
D
R
L
L
--
P
Y
W
Q
D
V
I
A
K
D
L
L
------------------------
S
G
-
K
T
-
V
M
I
A
A
H
G
N
S
L
R
G
L
V
K
H
L
E
G
I
---
S
D
----
A
--
D
I
---------
A
K
L
-
N
I
P
T
G
I
P
L
V
F
E
L
D
E
-
N
L
--------
K
P
--
S
K
P
S
Y
Y
L
D
P
E
A
A
A
A
G
A
A
A
V
85
HHSearch
67.58
22%
-64
- C2 -
1RII
1
GPMA_MYCTU
A:
[5-224]
G
S
L
V
L
L
R
H
G
E
S
D
W
N
A
L
N
L
F
T
G
W
-
V
D
V
G
L
T
D
K
G
Q
A
E
A
V
R
S
G
E
L
I
A
E
H
D
L
L
P
D
V
L
Y
T
S
L
L
R
R
A
I
T
T
A
H
-
L
A
L
D
S
A
----
D
RLW-
I
P
--
V
R
R
S
W
R
L
N
E
R
H
Y
G
A
L
Q
G
L
D
K
-----
A
E
T
K
A
---
R
Y
--------
G
E
E
Q
F
-
M
A
W
--
R
R
S
------------------------
Y
------------------------
D
TPPPPIERGSQFSQDADPRYAD
I
G
G
G
--
P
L
T
E
---------
C
L
A
D
V
V
A
R
F
L
--
P
Y
F
T
D
V
I
V
G
D
L
R
------------------------
V
G
-
K
T
-
V
L
I
V
A
H
G
N
S
L
R
A
L
V
K
H
L
D
Q
M
---
S
D
----
D
--
E
I
---------
V
G
L
-
N
I
P
T
G
I
P
L
R
Y
D
L
D
S
-
A
M
--------
R
P
--
L
V
R
G
G
T
Y
L
D
P
E
A
A
A
A
G
A
A
A
16
PsiBlast_PDB
65.56
33%
-61
- C2 -
1V37
1
?
A:
[1-144]
M
E
L
W
L
V
R
H
G
E
T
L
W
N
R
E
G
R
L
L
G
W
T
-
D
L
P
L
T
A
E
G
E
A
Q
A
R
R
L
K
G
A
L
P
S
--
L
---
P
A
F
S
S
D
L
L
R
A
R
R
T
A
E
-
L
---
A
G
----
F
----
S
P
R
---
L
Y
P
E
L
R
E
I
H
F
G
A
L
E
G
A
L
W
-----
E
T
L
D
P
---
R
Y
--------
K
E
A
-
L
-
L
R
F
QG
F
H
P
------------------------
P
------------------------------------------------------
G
G
E
---------
S
L
S
A
F
Q
E
R
V
F
--
R
F
L
E
G
L
K
A
--------------------------------
P
-
A
V
L
F
T
H
G
G
V
V
R
A
V
L
R
A
L
G
E
D
---
G
L
----
V
--
P
P
-
G
-------
S
A
V
-
A
V
D
W
P
R
R
V
L
V
R
L
A
L
-
D
--------------------------------
8
PsiBlast_PDB
65.15
34%
-62
- C2 -
2P9Z
2
?
A:
[1-144]
M
E
L
W
L
V
R
H
G
E
T
L
W
N
R
E
G
R
L
L
G
W
T
-
D
L
P
L
T
A
E
G
E
A
Q
A
R
R
L
K
G
A
L
P
S
--
L
---
P
A
F
S
S
D
L
L
R
A
R
R
T
A
E
-
L
---
A
G
----
F
----
S
P
R
-
L
H
--
P
E
L
R
E
I
H
F
G
A
L
E
G
A
L
W
-----
E
T
L
D
P
---
R
Y
--------
K
E
A
-
L
-
L
R
F
QG
F
H
P
------------------------
P
------------------------------------------------------
G
G
E
---------
S
L
S
A
F
Q
E
R
V
F
--
R
F
L
E
G
L
K
A
--------------------------------
P
-
A
V
L
F
T
H
G
G
V
V
R
A
V
L
R
A
L
G
E
D
---
G
L
----
V
--
P
P
-
G
-------
S
A
V
-
A
V
D
W
P
R
R
V
L
V
R
L
A
L
-
D
--------------------------------
41
PsiBlast_CBE
65.07
33%
-60
- C2 -
2ENU
1
?
A:
[1-144]
M
E
L
W
L
V
R
H
G
E
T
L
W
N
R
E
G
R
L
L
G
W
T
-
D
L
P
L
T
A
E
G
E
A
Q
A
R
R
L
K
G
A
L
P
S
--
L
---
P
A
F
S
S
D
L
L
R
A
R
R
T
A
E
-
L
---
A
G
----
F
----
S
P
R
---
L
Y
P
E
L
R
E
I
H
F
G
A
L
E
G
A
L
W
-----
E
T
L
D
P
---
R
Y
--------
K
E
A
-
L
-
L
R
F
QG
F
H
P
------------------------
P
------------------------------------------------------
G
G
E
---------
S
L
S
A
F
Q
E
R
V
F
--
R
F
M
E
G
L
K
A
--------------------------------
P
-
A
V
L
F
T
H
G
G
V
V
R
A
V
L
R
A
L
G
E
D
---
G
L
----
V
--
P
P
-
G
-------
S
A
V
-
A
V
D
W
P
R
R
V
L
V
R
L
A
L
-
D
--------------------------------