@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0810: (2015-12-03 )
MTKYQETAKAILAAVGGEKNIQHVTHCVTRLRLVLDNDEIVNDQVIKTIPNVIGVMRKNDQYQIILGNDVNNYYNAFLALGHFENTTREFSSQKKSSILEKLIETIAGVITPLIPALLGGGMLKVIGILLPMLGIASSSSQTVAFINFFGDAAYYFMPIMIAYSAASRFKVTPVLAATVGGILLHPAFVTMVAEGKPLSLFGAPVTLASYGSSVIPILIMVFLMQYIERWINKIVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGKGLSSAMLSIYHVAPWLALSILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGAASLAVAVKAKQKQTRQVAFAAGLSALLAGITEPALYGVTLKFKKPLYAAMISGGLVGAYIGLVNIASYTFVVPSIIGLPQYINPQGGNNFSNAVIAAIATIILTFIITWFLGIDEGENEKSSINAQEHTHIRSGLSKKETLYSPMVGNVLPLSKVPDETFSSKLLGEGLAITPSVGEVYAPFDGEIISLFPTKHAIALKDDKGVEVLIHIGIDTVELNGEGFEQLVKVGDFVKRGQLLLRMDIDFISSKGYSLISPVVVTNSIDQLEIIVKDAETMVTNEDDLLVIL
Atome Classification :
(20 SA)
------------.........10.......--------.20........-30........40........50-.........-------60....-----...-.70..------......80........90....---------------....100.......110.......-120.......130...------------...-.140......--------.150......----.160.......----170.......180.........190.......200.......--------210.......220.......230.----......240.......250.....------..260....-.---..270.......280..--.....290.......300.......310..-----.....320.......--330.......340-------.......350.......360.......370.-----......380.......390.....------..400.....------..410......--.420.......430..---------------.....440........450.......460.......470...---....480.......490.....---------------..500.......510.......520.......530.......540.......550-------.........560..-.....570.......580.......590....----...600.......610......-----------------.620----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------MT
K
Y
Q
E
T
A
K
A
I
L
A
AVGGE--------K
N
I
Q
H
V
T
H
C
V
T
-
R
L
R
L
V
LDNDEIV
N
D
Q
V
I
K
T
I
P
--
N
V
I
G
V
MRKN-------D
Q
Y
Q
I
I
-----LGN-D
V
N
N
Y
------
Y
N
A
F
L
A
LGHFE
N
T
T
R
E
F
S
S
Q
K
K
---------------
S
S
I
L
E
K
L
I
E
T
I
A
G
V
I
T
P
L
I
P
A
L
LG-
G
G
M
L
K
V
I
G
I
L
L
P
M
L
GI------------ASS-SS
Q
T
V
A
F
I
N
F--------FGD
A
A
Y
Y
F
M
P
----
I
M
I
A
YSAAS
R
F
----
K
V
T
P
V
L
A
A
TVG--
G
I
L
L
H
P
A
F
V
T
M
VAEGK
P
L
S
LFGAP
V
T
L
A
S--------YGS
S
V
I
P
I
L
I
M
V
F
L
M
Q
Y
I
E
R
W
I
N
K
----
I
V
P
S
V
M
K
S
F
LQ
P
T
L
I
I
L
I
S
G
F
L
A
L
------
V
V
VG
P
L
G
V
I
-
I
---GK
G
L
S
S
A
M
L
S
I
Y
HV
A
P
W
--
L
A
L
S
I
L
G
A
I
M
P
L
V
V
M
TG
M
H
W
A
F
A
P
I
F
L
A
AS-----VATP
D
V
L
I
L
P
A
M
L
A
S
--
N
L
A
Q
G
A
A
S
L
A
V
A
V
-------
K
AKQ
K
Q
T
R
Q
V
A
F
A
A
G
L
S
A
L
L
A
G
ITEP
A
L
Y
G
V
-----
T
L
K
FKK
P
L
Y
A
A
M
ISG
G
L
V
G
A
Y
I
G
L
------
V
N
IA
S
Y
T
F
V
V
------
P
S
I
IGLPQYIN--PQGGN
N
F
S
N
A
V
I
A
A
I
A
---------------
T
I
I
L
T
F
-
I
I
T
W
F
LGIDEGENEKSSIN
A
Q
E
H
T
H
I
R
SGLSK
K
E
T
---LYSPMVGNVLPLSKVP
D
E
T
F
S
S
---------------
K
L
LGEG
L
A
ITPSVG
E
V
YAPFDG
E
I
I
S
L
FPT
K
H
A
I
A
LKDDKG
V
E
V
L
I
H
IG
I
D
T
V
---------
E
LN
G
E
G
F
E
Q
L
V
K
V
G
-
D
F
V
K
RG
Q
L
L
L
R
M
D
I
D
FISSKGY
S
L
I
S
P
V
V
VTN----SI
D
Q
L
E
I
I
V
KD
A
E
T
MVTNED
D
L
-----------------
L
V
IL----------
2
PsiBlast_PDB
75.19
43%
-84
- C5 -
1GPR
-
A:
[12-160]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
V
---
F
V
S
P
I
T
G
E
I
H
P
I
T
D
V
P
D
Q
V
F
S
G
---------------
K
M
M
G
D
G
F
A
I
L
P
S
E
G
I
V
V
S
P
V
R
G
K
I
L
N
V
F
P
T
K
H
A
I
G
L
Q
S
D
G
G
R
E
I
L
I
H
F
G
I
D
T
V
---------
S
L
K
G
E
G
F
T
S
F
V
S
E
G
-
D
R
V
E
P
G
Q
K
L
L
E
V
D
L
D
A
V
K
P
N
V
P
S
L
M
T
P
I
V
F
T
N
----
L
A
E
G
E
T
V
S
I
K
A
S
G
S
V
N
R
E
Q
E
D
I
-----------------
V
K
I
E
----------
52
Fugue
72.54
16%
-105
- C2 -
4CR2
-
RPN1_YEAST
Z:
[49-993]
LELL
V
E
R
L
K
E
DD
S
S
L
Y
E
A
S
L
N
A
L
K
E
S
I
K
N
S
TSSMTAVP
K
P
L
K
F
L
R
P
T
Y
P
-
D
L
C
S
I
Y
D
K
W
T
--
D
P
N
L
K
S
S
L
A
--
D
V
L
S
I
L
A
M
T
Y
SENGKH
D
S
L
R
Y
R
-----
L
L
S
-
D
V
S
D
F
E
GWGHE
Y
I
R
H
L
A
L
E
I
G
E
V
Y
N
D
Q
V
E
K
D
A
E
D
ETSSDGSKSDGSAA
T
S
G
F
E
F
S
K
E
D
T
L
R
L
C
L
D
I
V
P
Y
F
L
K
H
N
G
E
E
D
A
V
D
L
L
L
E
I
E
S
I
D
K
L
P
Q
F
V
DENTF
Q
R
V
-
C
Q
Y
M
V
A
C
V
P
L
LPPPEDV
A
F
L
K
T
A
Y
S
I
Y
L
S
Q
NE
L
T
D
A
I
A
L
A
V
R
L
GE
E
D
M
I
R
S
V
F
D
A
T
S
D
--
P
V
M
H
K
Q
L
A
Y
I
L
A
A
Q
K
T
S
F
E
Y
E
G
V
Q
D
I
I
G
N
G
KLSEHFL
Y
L
A
K
E
L
N
L
T
G
P
K
V
P
E
D
I
Y
K
S
H
L
D
N
S
K
S
V
F
S
S
A
G
L
D
S
A
Q
Q
N
L
A
S
S
F
V
N
G
F
L
N
L
GYCND
K
L
I
V
D
N
D
N
W
V
-
Y
KTK
G
D
G
M
T
S
A
V
A
S
I
G
S
I
Y
Q
W
N
L
D
G
L
Q
Q
L
D
K
Y
L
Y
V
D
E
P
E
V
K
A
G
A
L
L
G
I
G
I
S
A
S
GVHDG
E
V
E
P
A
L
L
L
L
Q
D
Y
V
T
N
PD
T
K
I
S
S
A
A
I
L
G
L
G
I
A
F
AGSKN
D
E
V
L
G
L
L
L
P
I
A
A
S
T
D
L
P
I
E
T
A
A
M
A
S
L
A
L
A
H
V
F
VGTC
N
G
D
I
T
T
S
I
M
D
N
F
L
E
R
T
A
I
E
L
K
T
D
W
------
V
R
F
L
A
L
A
L
G
I
L
Y
MGQG
E
Q
V
D
D
V
L
E
T
I
S
A
I
E
H
P
M
T
S
A
I
E
V
L
V
G
S
C
A
Y
TGTGD
V
L
L
I
Q
D
L
L
H
R
L
T
L
A
Y
-
A
V
L
G
I
A
L
I
A
L
G
E
D
I
G
K
E
M
S
L
R
H
F
G
H
L
M
H
Y
G
N
E
H
I
R
---
R
M
V
P
L
A
M
G
I
V
S
V
S
D
P
Q
M
K
V
F
D
T
L
T
R
F
S
H
DAD
L
E
V
S
M
N
S
I
F
A
M
G
L
C
G
A
G
T
N
N
A
R
L
A
Q
L
L
R
Q
L
A
S
Y
Y
S
R
E
-
Q
D
A
L
F
I
T
R
L
A
Q
G
L
L
H
L
G
K
G
T
M
TMDVFNDAH
V
L
N
K
V
T
L
A
S
I
L
T
T
A
V
G
L
V
S
P
S
F
M
L
K
H
H
Q
L
F
Y
M
L
N
A
G
I
R
P
K
F
I
L
A
L
N
D
----
E
G
E
P
I
K
V
N
V
R
V
G
Q
P
V
L
L
N
H
G
E
R
A
E
LETDEYISYTSHIEG
V
V
I
L
K
K
NPDYREEE
51
Fugue
72.28
15%
-91
- C1 -
4LLG
-
RPOD_ECOLI
F:
[6-612]
-----------------
Q
S
Q
L
K
L
L
V
T
R
G
K
E
--------
Q
G
Y
L
T
Y
A
E
V
N
D
-
H
L
P
-----
E
D
I
V
D
S
D
Q
I
E
D
I
I
--
Q
M
I
-----
N
-------
D
M
G
I
Q
V
-----
M
G
R
-
T
T
D
P
V
------
R
M
Y
M
R
E
M
G
T
V
E
L
L
T
R
E
G
E
I
D
I
A
---------------
K
R
I
-
E
D
G
I
N
Q
V
Q
C
S
V
A
E
----------
Y
P
E
A
I
T
Y
L
L
E
Q
Y
D
R
------------
V
E
A
E
E
A
R
L
S
D
L
I
T
G
--------
F
V
D
D
-------------
P
E
L
A
R
E
K
F
----
A
E
L
R
A
Q
Y
V
V
T
R
--
D
T
I
K
A
T
A
Q
E
E
I
L
K
L
S
E
V
F
K
Q
F
--
R
L
V
P
K
Q
--------
F
D
Y
L
V
N
S
M
R
V
M
M
D
R
V
R
T
Q
E
R
L
I
M
K
----
L
C
V
E
Q
C
K
M
-
P
K
K
N
F
I
T
L
F
T
G
N
E
T
S
------
D
T
W
F
N
A
A
I
A
-
M
---
N
K
P
W
S
E
K
L
H
D
V
----
S
E
--
E
V
H
R
A
L
Q
K
L
Q
Q
I
E
E
E
T
G
L
T
-----------------------------
I
E
--
Q
V
K
D
I
N
R
R
M
S
I
G
--------
E
A
K
A
R
R
A
K
K
E
M
V
E
A
N
L
R
L
V
I
S
I
A
K
K
Y
T
N
R
G
L
-----
Q
-------
F
L
D
L
I
Q
E
G
N
I
G
L
M
K
A
V
------
D
K
F
-----------------------
E
--
Y
R
R
G
Y
K
F
S
T
Y
A
T
W
W
I
R
---------------
Q
A
I
T
R
S
-
I
A
D
Q
--------
A
R
T
I
R
I
P
V
H
M
I
E
T
I
N
K
L
N
R
I
S
R
Q
---
M
L
Q
E
M
G
R
E
P
T
P
E
E
L
A
E
R
M
L
M
P
E
---------------
D
K
I
R
K
V
L
K
I
A
K
E
P
I
S
M
E
T
P
I
G
D
D
-----
E
D
S
H
L
G
D
F
I
E
D
T
T
L
E
----
L
P
L
D
S
A
---------
T
T
E
S
L
R
A
A
T
H
D
V
L
A
-
G
L
T
A
R
E
A
K
V
L
R
M
R
F
G
I
D
M
N
T
D
Y
T
L
E
E
V
G
K
Q
F
D
VTR
E
R
I
R
Q
I
E
A
K
A
L
R
K
L
R
H
P
S
R
S
E
V
L
-----------------
R
S
F
L
D---------
1
PsiBlast_PDB
72.01
43%
-85
- C5 -
1AX3
-
A:
[12-160]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
E
V
---
F
V
S
P
I
T
G
E
I
H
P
I
T
D
V
P
D
Q
V
F
S
G
---------------
K
M
M
G
D
G
F
A
I
L
P
S
E
G
I
V
V
S
P
V
R
G
K
I
L
N
V
F
P
T
K
H
A
I
G
L
Q
S
D
G
G
R
E
I
L
I
H
F
G
I
D
T
V
---------
S
L
K
G
E
G
F
T
S
F
V
S
E
G
-
D
R
V
E
P
G
Q
K
L
L
E
V
D
L
D
A
V
K
P
N
V
P
S
L
M
T
P
I
V
F
T
N
----
L
A
E
G
E
T
V
S
I
K
A
S
G
S
V
N
R
E
Q
E
D
I
-----------------
V
K
I
E
----------
24
HHSearch
70.60
43%
-71
- C5 -
1AX3
-
A:
[8-157]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
E
I
G
E
E
V
---
F
V
S
P
I
T
G
E
I
H
P
I
T
D
V
P
D
Q
V
F
S
G
---------------
K
M
M
G
D
G
F
A
I
L
P
S
E
G
I
V
V
S
P
V
R
G
K
I
L
N
V
F
P
T
K
H
A
I
G
L
Q
S
D
G
G
R
E
I
L
I
H
F
G
I
D
T
V
---------
S
L
K
G
E
G
F
T
S
F
V
S
E
G
-
D
R
V
E
P
G
Q
K
L
L
E
V
D
L
D
A
V
K
P
N
V
P
S
L
M
T
P
I
V
F
T
N
----
L
A
E
G
E
T
V
S
I
K
A
S
G
S
V
N
R
E
Q
E
D
I
-----------------
V
K
I
E
----------
11
PsiBlast_PDB
68.12
36%
-89
- C5 -
3OUR
-
?
B:
[23-161]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
N
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
D
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
T
R
I
A
E
E
G
-
Q
T
V
K
A
G
D
T
V
I
E
F
D
L
A
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
-----
M
D
E
I
K
E
L
N
K
L
S
G
S
V
V
V
G
E
T
P
V
-----------------
L
R
V
T
----------
9
PsiBlast_PDB
67.61
37%
-91
- C5 -
2MP0
1
PTGA_ECOLI
B:
[19-151]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T
I
E
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
D
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
S
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
K
R
I
A
E
E
G
-
Q
R
V
K
V
G
D
T
V
I
E
F
D
L
P
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
-----
M
D
E
I
K
E
L
I
K
L
S
G
S
V
T
V
G
E
T
P
V
-----------------
I
R
I
K
----------
26
HHSearch
67.54
34%
-88
- C5 -
1F3Z
1
PTGA_ECOLI
A:
[12-157]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
E
---
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
D
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
S
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
K
R
I
A
E
E
G
-
Q
R
V
K
V
G
D
T
V
I
E
F
D
L
P
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
----
M
D
E
I
K
E
L
I
K
L
-
S
G
S
V
T
V
G
E
T
P
V
-----------------
I
R
I
K
----------
5
PsiBlast_PDB
67.41
37%
-95
- C5 -
4JBW
-
PTGA_ECOLI
M:
[23-155]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TIE
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
D
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
S
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
K
R
I
A
E
E
G
-
Q
R
V
K
V
G
D
T
V
I
E
F
D
L
P
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
-----
M
D
E
I
K
E
L
I
K
L
S
G
S
V
T
V
G
E
T
P
V
-----------------
I
R
I
K
----------
6
PsiBlast_PDB
67.38
37%
-92
- C5 -
2F3G
-
PTGA_ECOLI
A:
[19-151]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T
I
E
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
D
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
S
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
K
R
I
A
E
E
G
-
Q
R
V
K
V
G
D
T
V
I
E
F
D
L
P
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
-----
M
D
E
I
K
E
L
I
K
L
S
G
S
V
T
V
G
E
T
P
V
-----------------
I
R
I
K
----------
4
PsiBlast_PDB
67.26
37%
-93
- C5 -
1F3Z
1
PTGA_ECOLI
A:
[12-144]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T
I
E
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
D
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
S
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
K
R
I
A
E
E
G
-
Q
R
V
K
V
G
D
T
V
I
E
F
D
L
P
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
-----
M
D
E
I
K
E
L
I
K
L
S
G
S
V
T
V
G
E
T
P
V
-----------------
I
R
I
K
----------
7
PsiBlast_PDB
67.22
37%
-93
- C5 -
1GGR
-
PTGA_ECOLI
A:
[19-151]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T
I
E
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
D
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
S
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
K
R
I
A
E
E
G
-
Q
R
V
K
V
G
D
T
V
I
E
F
D
L
P
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
-----
M
D
E
I
K
E
L
I
K
L
S
G
S
V
T
V
G
E
T
P
V
-----------------
I
R
I
K
----------
8
PsiBlast_PDB
67.15
37%
-92
- C5 -
1O2F
-
PTGA_ECOLI
A:
[19-151]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T
I
E
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
D
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
S
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
K
R
I
A
E
E
G
-
Q
R
V
K
V
G
D
T
V
I
E
F
D
L
P
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
-----
M
D
E
I
K
E
L
I
K
L
S
G
S
V
T
V
G
E
T
P
V
-----------------
I
R
I
K
----------
28
HHSearch
67.01
34%
-86
- C5 -
3OUR
-
?
B:
[20-165]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
E
---
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
N
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
D
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
T
R
I
A
E
E
G
-
Q
T
V
K
A
G
D
T
V
I
E
F
D
L
A
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
----
M
D
E
I
K
E
L
N
K
-
L
S
G
S
V
V
V
G
E
T
P
V
-----------------
L
R
V
T
----------
3
PsiBlast_PDB
67.01
37%
-91
- C5 -
1F3G
-
PTGA_ECOLI
A:
[19-151]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T
I
E
I
I
A
P
L
S
G
E
I
V
N
I
E
D
V
P
D
V
V
F
A
E
---------------
K
I
V
G
D
G
I
A
I
K
P
T
G
N
K
M
V
A
P
V
D
G
T
I
G
K
I
F
E
T
N
H
A
F
S
I
E
S
D
S
G
V
E
L
F
V
H
F
G
I
D
T
V
---------
E
L
K
G
E
G
F
K
R
I
A
E
E
G
-
Q
R
V
K
V
G
D
T
V
I
E
F
D
L
P
L
L
E
E
K
A
K
S
T
L
T
P
V
V
I
S
N
-----
M
D
E
I
K
E
L
I
K
L
S
G
S
V
T
V
G
E
T
P
V
-----------------
I
R
I
K
----------
25
HHSearch
66.25
33%
-56
- C5 -
2GPR
-
PTGA_MYCCT
A:
[10-158]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
K
N
L
K
---
V
L
A
P
C
D
G
T
I
I
T
L
D
E
V
E
D
E
V
F
K
E
---------------
R
M
L
G
D
G
F
A
I
N
P
K
S
N
D
F
H
A
P
V
S
G
K
L
V
T
A
F
P
T
K
H
A
F
G
I
Q
T
K
S
G
V
E
I
L
L
H
I
G
L
D
T
V
---------
S
L
D
G
N
G
F
E
S
F
V
T
Q
D
-
Q
E
V
N
A
G
D
K
L
V
T
V
D
L
K
S
V
A
K
K
V
P
S
I
K
S
P
I
I
F
T
N
----
N
G
G
K
T
-
L
E
I
V
K
M
G
E
V
K
Q
G
D
V
V
A
-----------------
I
L
K
-----------
10
PsiBlast_PDB
65.10
37%
-55
- C5 -
2GPR
-
PTGA_MYCCT
A:
[9-148]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
K
N
L
K
---
V
L
A
P
C
D
G
T
I
I
T
L
D
E
V
E
D
E
V
F
K
E
---------------
R
M
L
G
D
G
F
A
I
N
P
K
S
N
D
F
H
A
P
V
S
G
K
L
V
T
A
F
P
T
K
H
A
F
G
I
Q
T
K
S
G
V
E
I
L
L
H
I
G
L
D
T
V
---------
S
L
D
G
N
G
F
E
S
F
V
T
Q
D
-
Q
E
V
N
A
G
D
K
L
V
T
V
D
L
K
S
V
A
K
K
V
P
S
I
K
S
P
I
I
F
T
N
----
N
G
G
K
T
L
E
I
V
K
M
G
E
V
K
Q
G
D
V
V
A
I
-----------------
L
K
------------
53
Fugue
62.02
17%
-104
- C4 -
2GSA
2
GSA_SYNP6
A:
[6-432]
---------FKT
I
K
S
D
E
I
F
A
A
A
Q
K
L
M
P
G
G
V
--------
S
S
--------------
P
V
R
A
F
K
S
V
G
G
Q
P
I
V
F
D
R
--
V
K
D
A
Y
A
W
D
V
-------
D
G
N
R
Y
I
DYVGT
W
G
P
-
A
I
C
G
H
------
A
H
P
E
V
I
E
A
L
K
V
A
M
E
K
G
T
S
F
G
A
P
---------------
C
A
L
E
N
V
L
A
E
M
V
N
D
A
V
----------------------------------------
P
-
S
I
E
M
V
R
F
V
N
S
--------
G
T
E
A
C
M
A
V
L
R
----
L
M
R
A
Y
T
--
G
R
D
----
K
I
I
K
F
E
G
C
Y
H
G
HA
D
M
F
L
V
K
A
G
S
G
V
A
T
L
G
L
P
S
S
P
-
G
V
P
K
K
T
T
A
---------
N
T
L
T
T
P
Y
N
D
L
E
A
V
K
A
L
F
A
E
N
P
G
E
---------------------
I
A
G
V
I
L
E
------
P
I
V
G
N
S
G
F
I
V
P
---
D
A
G
F
L
E
G
L
R
E
I
T
L
E
H
D
----
A
L
L
V
F
D
E
-----
V
M
T
G
F
R
I
A
Y
G
G
V
Q
E
K
F
G
-----
V
-
T
P
D
L
T
T
L
G
K
I
I
G
G
--
G
L
--------------------------
P
V
G
A
Y
G
G
K
R
E
I
M
Q
L
V
A
----------------------------------------------------------------
P
A
G
P
M
--
Y
Q
A
G
T
L
S
G
N
P
L
A
M
T
A
G
---------------
I
K
T
L
E
L
-
L
--------------------
R
Q
P
G
T
Y
E
Y
L
D
Q
I
T
K
---
R
L
S
D
G
L
L
A
I
A
Q
E
T
G
H
A
------------------------------------
A
C
G
G
Q
V
S
G
M
F
G
F
F
F
T
--------
E
G
P
V
H
N
Y
E
D
A
K
K
S
D
L
---------
Q
K
F
S
R
F
H
R
G
M
L
E
Q
G
-
I
Y
L
A
P
S
Q
----
F
E
A
G
F
T
S
L
A
-----------
H
----
T
E
E
D
I
D
A
T
L
A
A
A
R
T
V
M
S
A
------------------------
L
----------
49
Fugue
58.20
11%
-87
* C4 *
3ODM
5
CAPPA_CLOPE
A:
[24-560]
--------MKIP
C
S
M
M
T
Q
H
P
D
N
V
E
T
Y
I
S
I
Q
--------
Q
E
P
A
E
A
I
K
G
L
T
P
Q
D
K
G
G
L
G
I
E
E
V
M
I
D
F
E
G
K
L
T
P
YH
Q
T
S
Q
I
A
L
G
L
-------
I
S
N
G
I
I
-----
P
G
K
-
D
V
-------------------
R
V
T
P
R
I
P
N
A
N
K
E
---------------
S
--
V
F
R
Q
L
M
S
I
M
S
I
I
E
T
N
V
Q
S
K
E
L
-
T
G
T
P
A
I
S
E
V
V
V
P
M
---------------
I
E
T
-
G
K
E
I
S
E
F
Q
D
R
--------
V
N
S
V
V
D
M
G
N
K
----
N
Y
K
T
K
L
D
L
N
S
V
----
R
I
I
P
L
V
----------------------------------------------
E
D
V
P
A
L
A
N
I
D
R
I
L
D
E
H
Y
E
I
E
K
S
----------
K
G
H
I
L
K
D
L
R
I
M
I
A
R
S
D
T
A
------
M
S
Y
G
L
I
S
G
V
-
L
---
S
V
L
M
A
V
D
G
A
Y
K
W
G
E
K
H
G
--
V
T
I
S
P
I
L
G
C
G
S
L
P
F
R
G
H
F
S
E
E
N
I
D
E
I
L
A
T
Y
-----
S
G
I
K
T
F
T
F
Q
S
A
L
R
Y
D
--
H
G
E
E
A
T
K
H
A
V
R
E
L
-------
K
E
K
I
A
Q
S
K
P
----
R
N
F
S
E
E
D
K
D
L
M
K
E
F
I
G
I
C
-----
S
K
H
Y
L
Q
T
F
L
K
V
I
D
T
V
S
F
V
S
D
F
I
P
K
NRDRLT
A
N
L
D
N
V
A
D
L
V
------
K
D
E
V
L
K
Q
E
I
L
S
--
I
D
N
S
K
E
Y
A
V
P
R
A
I
S
F
T
---------------
G
A
M
Y
T
L
G
M
P
P
E
L
M
G
------
M
G
R
A
L
N
E
I
K
T
K
Y
G
Q
E
G
I
D
K
L
L
E
---
I
Y
P
I
L
R
K
D
L
A
F
A
A
R
F
A
N
G
G
V
S
K
---------------
K
I
I
D
------------------------
E
E
A
R
Q
E
Y
K
E
D
M
K
Y
V
N
E
I
L
N
L
G
L
D
------------------
Y
D
F
L
N
E
N
-
E
F
Y
H
T
L
L
K
T
T
K
P
I
I
M
H
L
M
G
L
E
E
N
V
M
R
N
---------
S
T
E
E
L
K
I
L
N
E
W
I
V
R
M
G
K
V
R
G
S
I
-----------------
G
-------------
45
Fugue
57.26
35%
-61
- C5 -
3IPJ
1
?
A:
[1-95]
----------SN
A
N
K
Y
N
K
I
A
N
E
L
I
K
I
I
G
-
E
--------
D
N
I
I
S
I
T
H
C
A
T
-
R
L
R
V
M
V
K
D
R
E
I
I
N
D
K
K
V
E
K
V
D
--
E
V
K
G
V
F
F
T
S
-------
G
Q
Y
Q
I
I
-----
L
G
T
G
I
V
N
K
V
------
Y
A
E
V
E
K
M
G
L
K
T
L
S
K
K
E
Q
D
E
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------