@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0872: (2015-12-03 )
MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALSNCANSGINNVGVITQYQPLELNTHIGNGSSWGLDGIDSGVTVLQPYSATEGNRWFQGTSHAIYQNIDYIDRINPEYVLILSGDHIYKMDYDDMLQTHKDNLASLTVAVLDVPLKEASRFGIMNTDSNDRIVEFEEKPEHPKSTKASMGIYIFDWKRLRTVLIDGEKNGIDMSDFGKNVIPAYLESGERVYTYNFDGYWKDVGTIESLWEANMEYIGEDNKLHSRDRSWKIYSKNLIAPPNFMTEDANVKDSLVVDGCFVAGNVEHSILSTNVQVKPNAIIKDSFVMSGATIGEGAKINRAIIGEDAVIGDGVVIDGSKEVEVIGYKEVVGVPNED
Atome Classification :
(20 SA)
-.........10........20........30..-......40........50........60..-......70........80.........90........100.......110.......120......--.130.--......--140.......150.......160.......170.......180--.--...---------------------....---------------------.190.......200..--.....210.......220.......230..----------..-----------.-.--.240..--------......250.......-260..-..---.-..-------270.......-.280.-....------..290.----.....-.300...-.--.-..310.......320.......330-------------------..-------------------.....340.-......350.......360-----.......370-------........------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MKN
E
M
L
A
L
I
L
AGGQGT
R
L
G
K
L
T
Q
S
I
A
K
P
A
V
QFG-G
R
Y
R
I
I
D
F
A
L
S
N
C
A
NSGINN
V
G
V
I
T
Q
Y
Q
P
L
-
E
L
N
T
HIGNGSSWGLDGI-DSG
V
T
V
L
QPYSATEGNRWFQGT
S
H
A
I
Y
QNI
D
Y
I
DRINP
E
Y
V
L
I
LSG
D
H
--
I
Y
KM
D
--
Y
D
D
M
L
Q
--
T
H
KD
N
L
A
S
L
T
V
A
V
LDV
P
L
K
E
A
SRFGIMNTDSND
R
I
V
E
FEEK----P--EHP---------------------KSTK---------------------ASM
G
I
Y
I
F
D
W
K
R
L
R
T
V
--
L
IDGEKNGI
D
M
S
D
FG
K
N
V
I
P
A
Y
LESG
E
R
V
Y
----------
T
Y-----------N-F--D
G
Y
-W
K
--------
D
V
G
T
I
E
S
L
W
E
A
N
M
E
YI-GEDNK-LH---S-RD-------R
S
-
W
K
I
Y
SKN-LIAPP-NFMT------EDANVK----D
S
L
V
V
-
D
G
C
F
VAG-N--V-E
H
S
I
LSTN
V
Q
VKPN
A
I
I
KDS
F
V
MSG-------------------AT-------------------IGEG
A
K
I
N
R
-
A
I
IGEDAVIGD
G
V
V
IDGSK-----
E
V
E
V
I
G
Y
K
E
--------VVGVPNED------------------------------------------------------------------------------------
34
HHSearch
98.62
39%
-125
- C2 -
1YP2
6
GLGS_SOLTU
A:
[17-416]
-
A
S
R
S
V
L
G
I
I
L
------
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
A
N
Y
R
-
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
A
-------
E
G
F
V
E
V
L
A
A
Q
Q
S
P
E
N
P
D
W
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
--
Q
G
E
Q
L
Q
A
M
KVDTTILGLD
D
K
R
A
K
E
M
P
F
I
---------------------
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
---
G
A
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
D
F
S
---
F
-
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
R
Y
L
P
P
S
-
K
M
L
D
--------
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
--
N
C
K
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
27
PsiBlast_CBE
91.13
35%
-111
- C2 -
1YP2
6
GLGS_SOLTU
C:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
A
S
------
E
G
F
V
E
V
L
A
A
Q
Q
S
P
E
N
P
D
W
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
QG
E
Q
L
---------------------
Q
A
M
K
VDTTILGLD
D
K
R
A
K
E
M
P
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
33
HHSearch
90.85
38%
-108
- C2 -
3BRK
3
GLGC_RHIRD
X:
[9-396]
-
L
A
R
D
A
M
A
Y
V
L
A
G
G
R
G
S
R
L
K
E
L
T
D
R
R
A
K
P
A
V
Y
F
G
-
G
K
A
R
I
I
D
F
A
L
S
N
A
L
N
S
G
I
R
R
I
G
V
A
T
Q
Y
K
A
H
-
S
L
I
R
H
L
Q
R
G
W
D
F
F
R
P
E
R
-
N
E
S
F
D
I
L
P
A
S
-------
W
Y
E
G
T
A
D
A
V
Y
Q
N
I
D
I
I
E
P
Y
A
P
E
Y
M
V
I
L
A
G
D
H
--
I
Y
K
M
D
--
Y
E
Y
M
L
Q
--
Q
H
V
D
S
G
A
D
V
T
I
G
C
L
E
V
P
R
M
E
A
T
G
F
G
V
M
H
V
N
E
K
D
E
I
I
D
F
I
E
K
----
P
--
A
D
P
PGIPGNE--------------
G
F
A
L
---------------------
A
S
M
G
I
Y
V
F
H
T
K
F
L
M
E
A
--
V
R
R
D
A
A
D
----------
I
I
P
Y
I
V
E
H
G
-
K
A
V
----------
A
H
RFADSCVRSDF
E
-
H
--
E
P
Y
-
W
R
--------
D
V
G
T
I
D
A
Y
W
Q
A
N
I
D
L
T
-
D
V
V
P
D
-
L
D
---
I
-
Y
D
-------
K
S
-
W
P
I
W
T
Y
A
-
E
I
T
P
P
-
A
K
F
V
HDDEDR
R
G
S
A
V
-----
S
S
V
V
S
-
G
D
C
I
I
S
G
-
A
A-
L
-
N
R
S
L
L
F
T
G
V
R
A
N
S
Y
S
R
L
E
N
A
V
V
L
P
S
-------------------
V
K
-------------------
I
G
R
H
A
Q
L
S
N
-
V
V
I
D
H
G
V
V
I
P
E
G
L
I
V
G
E
D
P
-----
E
L
D
A
K
R
F
R
R
--------
T
E
S
G
I
C
L
I
------------------------------------------------------------------------------------
26
PsiBlast_CBE
89.48
35%
-111
- C2 -
1YP2
6
GLGS_SOLTU
D:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
-------N
E
G
F
V
E
V
L
A
A
Q
Q
S
P
-----
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
QG
E
Q
L
---------------------
Q
A
M
K
VDTTILGLD
D
K
R
A
K
E
M
P
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
3
PsiBlast_PDB
88.89
35%
-108
- C2 -
1YP4
5
GLGS_SOLTU
A:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
A
--------
G
F
V
E
V
L
A
A
Q
Q
S
P
E
N
P
D
W
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
QG
E
Q
L
---------------------
Q
A
M
K
VDTTILGLD
D
K
R
A
K
E
M
P
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
22
PsiBlast_CBE
88.87
35%
-105
- C2 -
1YP4
6
GLGS_SOLTU
C:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
A
S
------
E
G
F
V
E
V
L
A
A
Q
Q
S
P
E
N
P
D
W
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
QG
E
Q
L
---------------------
Q
A
M
K
VDTTILGLD
D
K
R
A
K
E
M
P
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
1
PsiBlast_PDB
88.69
34%
-106
- C2 -
3BRK
3
GLGC_RHIRD
X:
[9-402]
-
L
A
R
D
A
M
A
Y
V
L
A
G
G
R
G
S
R
L
K
E
L
T
D
R
R
A
K
P
A
V
Y
F
G
-
G
K
A
R
I
I
D
F
A
L
S
N
A
L
N
S
G
I
R
R
I
G
V
A
T
Q
Y
K
A
H
-
S
L
I
R
H
L
Q
R
G
W
D
F
F
R
P
E
R
-
N
E
S
F
D
I
L
P
A
S
-------
W
Y
E
G
T
A
D
A
V
Y
Q
N
I
D
I
I
E
P
Y
A
P
E
Y
M
V
I
L
A
G
D
H
--
I
Y
K
M
D
--
Y
E
Y
M
L
Q
--
Q
H
V
D
S
G
A
D
V
T
I
G
C
L
E
V
P
R
M
E
A
T
G
F
G
V
M
H
V
N
E
K
D
E
I
I
D
F
I
E
K
----
P
--
A
D
P
---------------------
P
G
I
P
GNEGFAL--------------
A
S
M
G
I
Y
V
F
H
T
K
F
L
M
E
A
--
V
R
R
D
A
A
D
----------
I
I
P
Y
I
V
E
H
G
K
A
V
A
HRFADSCVRS
D
F
-----------
E
-
H
--
E
P
Y
-
W
R
--------
D
V
G
T
I
D
A
Y
W
Q
A
N
I
D
L
T
-
D
V
V
P
D
-
L
D
---
I
-
Y
D
-------
K
S
-
W
P
I
W
T
Y
A
-
E
I
T
P
P
A
K
F
V
H
------
D
D
E
D
R
R
GSAV
S
S
V
V
S
-
G
D
C
I
I
S
G
A
A
--
L
-
N
R
S
L
L
F
T
G
V
R
A
N
S
Y
S
R
L
E
N
A
V
V
L
P
S
-------------------
V
K
-------------------
I
G
R
H
A
Q
L
S
N
-
V
V
I
D
H
G
V
V
I
P
E
G
L
I
V
G
E
D
P
-----
E
L
D
A
K
R
F
R
R
--------
T
E
S
G
I
C
L
I
------------------------------------------------------------------------------------
21
PsiBlast_CBE
88.60
35%
-110
- C2 -
1YP4
4
GLGS_SOLTU
D:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
--------
E
G
F
V
E
V
L
A
A
Q
Q
S
P
E
-----
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
Q
G
E
Q
L
---------------------
Q
A
M
K
VDTTILGLD
D
K
R
A
K
E
M
P
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
28
PsiBlast_CBE
88.48
35%
-105
- C2 -
1YP2
6
GLGS_SOLTU
B:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
A
S
-----N
E
G
F
V
E
V
L
A
A
Q
Q
S
P
E
----
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
QG
E
Q
L
---------------------
Q
A
M
K
VDTTILGLDDK
R
A
K
E
M
P
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
DYYET
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
25
PsiBlast_CBE
87.46
35%
-105
- C2 -
1YP3
5
GLGS_SOLTU
C:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
A
S
------
E
G
F
V
E
V
L
A
A
Q
Q
S
P
E
N
P
D
W
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
Q
G
E
Q
L
---------------------
Q
A
M
K
VDTTILGLD
D
K
R
A
K
E
M
P
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
23
PsiBlast_CBE
87.20
35%
-103
- C2 -
1YP4
6
GLGS_SOLTU
B:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
A
S
N
M
---N
E
G
F
V
E
V
L
A
A
Q
Q
S
P
E
N
---
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
Q
G
E
Q
L
---------------------
Q
A
M
K
VDTTILGLDD
K
R
A
K
E
M
P
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
24
PsiBlast_CBE
86.53
35%
-107
- C2 -
1YP3
3
GLGS_SOLTU
D:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
-------N
E
G
F
V
E
V
L
A
A
Q
Q
S
P
E
------
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
QG
E
Q
L
---------------------
Q
A
M
K
VDTTILGLD
D
K
R
A
K
E
MP
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVP
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
2
PsiBlast_PDB
86.05
35%
-106
- C2 -
1YP3
5
GLGS_SOLTU
A:
[32-414]
----------------
T
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
--------
E
G
F
V
E
V
L
A
A
Q
Q
S
P
E
N
P
D
W
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
QG
E
Q
L
---------------------
Q
A
M
K
VDTTILGLD
D
K
R
A
K
E
M
P
F
I
--
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
-
K
K
P
V
P
-
D
F
---
S
F
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
K
M
L
-------
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
G
S
V
P
I
G
-------------------
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
--------
D
G
Y
F
I
K
S
G
------------------------------------------------------------------------------------
55
Fugue
82.71
37%
-92
- C2 -
1YP2
6
GLGS_SOLTU
A:
[10-451]
Q
T
C
L
D
P
D
A
S
R
S
V
L
G
I
I
L
R
L
Y
P
L
T
K
K
R
A
K
P
A
V
P
L
G
-
A
N
Y
R
L
I
D
I
P
V
S
N
C
L
N
S
N
I
S
K
I
Y
V
L
T
Q
F
N
S
A
-
S
L
N
R
H
L
S
R
A
Y
A
E
G
-------
F
V
E
V
L
A
A
Q
Q
S
P
E
N
P
D
W
F
Q
G
T
A
D
A
V
R
Q
Y
L
W
L
F
E
E
H
T
V
L
E
Y
L
I
L
A
G
D
H
--
L
Y
R
M
D
--
Y
E
K
F
I
Q
--
A
H
R
E
T
D
A
D
I
T
V
A
A
L
P
M
D
E
K
R
A
T
A
F
G
L
M
K
I
D
E
E
G
R
I
I
E
F
A
E
K
----
P
--
Q
G
E
---------------------
Q
L
Q
A
M
KVDTTILGLD
D
K
R
A
K
E
M
P
F
I
A
S
M
G
I
Y
V
I
S
K
D
V
M
L
N
L
--
L
R
D
K
F
P
G
A
---
N
D
F
G
S
E
V
I
P
G
A
T
S
L
G
M
R
V
Q
----------
A
Y
-----------
L
-
Y
--
D
G
Y
-
W
E
--------
D
I
G
T
I
E
A
F
Y
N
A
N
L
G
I
T
K
K
P
V
P
D
-
F
S
---
F
-
Y
D
-------
R
S
-
A
P
I
Y
T
Q
P
-
R
Y
L
P
P
-
S
-
K
M
------
L
D
A
D
V
T
----
D
S
V
I
G
-
E
G
C
V
I
K
N
C
K
--
I
-
H
H
S
V
V
G
L
R
S
C
I
S
E
G
A
I
I
E
D
S
L
L
M
G
A
-------------------
D
Y
Y
E
T
D
A
D
R
K
L
L
A
A
K
GSVPIG
I
G
K
N
C
H
I
K
R
-
A
I
I
D
K
N
A
R
I
G
D
N
V
K
I
I
N
K
D
-----
N
V
Q
E
A
A
R
E
T
DG
Y
F
I
K
SG
I
V
T
V
I
K
D
A
L
I
P
S
GIII----------------------------------------------------------------------------
35
HHSearch
62.43
21%
-96
- C2 -
2GGO
-
?
A:
[1-330]
-----
M
K
A
F
I
L
A
A
G
S
G
E
R
L
E
P
I
T
H
T
R
P
K
A
F
V
P
I
L
-
S
K
P
-
L
I
E
Y
Q
I
E
Y
L
R
K
C
G
I
R
D
I
T
V
I
V
S
S
K
N
K
E
Y
F
E
K
K
L
K
E
-------------
I
S
I
--
V
T
Q
----
K
D
D
I
K
G
T
G
A
A
I
L
S
A
K
F
--
N
----
D
E
A
L
I
I
Y
G
D
L
--
F
F
S
N
E
K
E
I
C
N
I
I
T
--
L
K
----
E
N
A
I
I
G
V
-
K
V
S
--
N
P
K
D
Y
G
V
L
V
L
D
N
Q
N
N
L
S
K
I
I
E
K
----
P
--
E
I
P
---------------------
P
S
N
L
---------------------
I
N
A
G
I
Y
K
L
N
S
D
I
F
T
Y
L
--
D
K
-
I
S
I
-
S
E
R
G
E
L
E
L
T
D
A
I
N
L
M
A
K
-
D
H
R
V
K
----------
V
I
-----------
E
-
Y
--
E
G
Y
-
W
M
--------
D
I
G
K
P
W
N
I
I
D
V
N
K
W
A
L
-
D
N
L
V
F
-
S
Q
NL
G
N
-
V
E
-------
D
N
-
V
K
I
K
G
K
V
-
I
I
E
E
D
-
A
E
I
K
------
S
G
T
Y
I
E
G---
P
V
Y
I
G
-
K
G
S
E
I
G
P
-
N
S
Y
L
R
P
Y
T
I
L
V
E
K
N
K
I
G
A
S
V
E
V
K
E
S
V
I
M
E
G
-------------------
S
K
-------------------
I
P
H
L
S
Y
V
G
D
-
S
V
I
A
E
D
V
N
F
G
A
G
T
L
I
A
N
L
R
-----
F
D
E
K
E
V
K
V
N
--------
V
K
G
K
R
I
S
S
------------------------------------------------------------------------------------
63
Fugue
60.10
17%
-89
- C2 -
1HV9
4
GLMU_ECOLI
A:
[4-451]
---
N
A
M
S
V
V
I
L
A
A
G
K
G
T
R
M
Y
---
S
D
L
P
K
V
L
H
T
L
A
-
G
K
A
-
M
V
Q
H
V
I
D
A
A
N
E
L
G
A
A
H
V
H
L
V
Y
G
H
G
G
D
-
L
L
K
Q
A
L
K
D
----------
D
N
L
N
W
V
L
Q
A
E
Q
--------
L
G
T
G
H
A
M
Q
Q
A
A
P
F
F
A
--
D
D
E
D
I
L
M
L
Y
G
D
V
--
P
--
L
I
--
S
V
E
T
L
Q
--
R
L
R
D
A
K
P
Q
G
G
I
G
L
L
T
V
K
L
D
D
P
T
G
Y
G
R
I
T
R
E
-
N
G
K
V
T
G
I
V
E
H
KDAT
D
--
E
Q
R
---------------------
Q
I
Q
E
---------------------
I
N
T
G
I
L
I
A
N
G
A
D
M
K
R
W
--
L
A
K
L
T
N
N
N
A
Q
G
E
Y
Y
I
T
D
I
I
A
L
A
Y
Q
E
G
R
E
I
V
----------
A
V
-----------
H
-
P
QR
L
S
E
-
V
E
--------
G
V
N
N
R
L
Q
L
S
R
L
E
R
V
Y
Q
-
S
E
Q
A
E
-
K
L
---
L
-
L
A
GVMLRDP
A
R
-
F
D
L
R
G
T
L
-
T
H
G
R
D
-
V
E
I
D
------
T
N
V
I
I
E
----
G
N
V
T
L
G
H
R
V
K
I
G
T
-
G
C
V
I
-
K
N
S
V
I
G
D
D
C
E
I
S
P
Y
T
V
V
E
D
A
N
L
A
A
A
-------------------
C
T
-------------------
I
G
P
F
A
R
L
R
P
G
A
E
L
L
E
G
A
H
V
G
N
F
V
E
M
K
K
A
R
L
G
K--
G
S
K
A
G
H
L
T
Y
--------
L
G
D
A
E
I
G
D
N
V
N
I
G
A
GTITCNYDGA
N
K
F
K
T
I
I
G
D
D
V
F
V
G
S
D
T
Q
L
V
A
P
V
T
V
G
K
G
A
T
I
A
AGTTVT
R
N
V
G
EN
A
L
A
I
SRVP
Q
T
Q
K
E
GWRR-------
60
Fugue
58.85
18%
-89
- C2 -
1HM9
6
GLMU_STRPN
A:
[11-468]
----
S
N
F
A
I
I
L
A
A
G
K
G
T
R
M
K
---
S
D
L
P
K
V
L
H
K
V
A
-
G
I
S
-
M
L
E
H
V
F
R
S
V
G
A
I
Q
P
E
K
T
V
T
V
V
G
H
K
A
E
-
L
V
E
E
V
L
A
G
Q
T
E
F
V
T
Q
S
E
-
Q
------------------
L
G
T
G
H
A
V
M
M
T
E
P
I
L
E
G
-
L
S
G
H
T
L
V
I
A
G
D
T
PL
I
T
G
E
S
--
L
K
N
L
I
D
--
F
H
I
N
H
K
N
V
--
A
T
I
L
T
A
E
T
D
N
P
F
G
Y
G
R
I
V
R
N
D
N
A
E
V
L
R
I
V
E
Q
KDAT
D
--
F
E
K
---------------------
Q
I
K
E
---------------------
I
N
T
G
T
Y
V
F
D
N
E
R
L
F
E
A
--
L
K
N
I
N
T
N
N
A
Q
G
E
Y
Y
I
T
D
V
I
G
I
F
R
E
T
G
E
K
V
G
----------
A
Y
-----------
T
-
L
--
K
D
F
-
D
E
SLGVND
R
V
A
L
A
T
A
E
S
V
M
R
R
R
I
N
H
K
-
H
M
V
N
G
-
V
S
F
--
V
-
N
P
-------
E
A
-
T
Y
I
D
I
D
V
-
E
I
A
P
E
-
V
Q
I
E
------
A
N
V
I
L
K
----
G
Q
T
K
I
G
A
E
T
V
L
T
N
-
G
T
Y
V
-
V
D
S
T
I
G
A
G
A
V
I
-
T
N
S
M
I
E
E
S
S
V
A
D
G
-------------------
V
T
-------------------
V
G
P
Y
A
H
I
R
P
N
S
S
L
G
A
Q
V
H
I
G
N
F
V
E
V
K
G
S
S
I
G
E
NT
K
A
G
H
L
T
Y
I
G
--------
N
C
E
V
G
S
N
V
N
F
G
A
G
T
I
T
V
N
Y
DGK
N
K
Y
K
T
V
I
G
D
N
V
F
V
G
S
N
S
T
I
I
A
P
V
E
L
G
D
N
S
L
V
G
AGSTIT
K
D
V
P
AD
A
I
A
I
G
R
G
R
Q
I
N
K
D
EYATRLPHHPKNQ
4
PsiBlast_PDB
55.97
31%
-95
- C2 -
3HL3
1
?
A:
[24-254]
----
A
M
K
G
I
I
L
A
G
G
T
G
S
R
L
Y
P
I
T
K
V
T
N
K
H
L
L
P
V
G
--
R
Y
P
M
I
Y
H
A
V
Y
K
L
K
Q
C
D
I
T
D
I
M
I
I
T
G
K
E
-------
H
M
G
D
V
V
S
F
L
G
S
G
Q
-
E
F
G
V
S
F
T
Y
R
V
Q
D
K
A
G
-----
G
I
A
Q
A
L
G
L
C
E
D
F
V
G
--
N
D
R
M
V
V
I
L
-
G
D
N
--
I
F
S
D
D
--
I
R
P
Y
V
E
E
F
T
N
Q
K
E
G
A
K
V
L
L
Q
S
V
D
D
P
----
E
R
F
G
V
A
N
I
-
Q
N
R
K
I
I
E
I
E
E
K
----
P
--
K
E
P
---------------------
K
S
S
Y
---------------------
A
V
T
G
I
Y
L
Y
D
S
K
V
F
S
Y
I
K
E
L
K
P
S
A
R
G
E
L
E
I
T
D
I
N
N
----
W
Y
L
K
R
G
--
V
L
----------
T
Y
-----------
N
E
M
--
S
G
W
-
W
T
--------
D
A
G
T
H
V
S
L
Q
R
A
N
A
L
A
R
-
D
I
N
F
G
-
K
Q
---
F
-
N
G
-------
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
Fugue
54.98
18%
-86
- C2 -
1FXJ
2
GLMU_ECOLI
A:
[3-329]
--
N
N
A
M
S
V
V
I
L
A
A
G
K
G
T
R
M
Y
---
S
D
L
P
K
V
L
H
T
L
A
-
G
K
A
-
M
V
Q
H
V
I
D
A
A
N
E
L
G
A
A
H
V
H
L
V
Y
G
H
G
G
D
-
L
L
K
Q
A
L
K
D
D
N
L
----------
N
W
V
L
Q
A
E
Q
--------
L
G
T
G
H
A
M
Q
Q
A
A
P
F
F
A
--
D
D
E
D
I
L
M
L
Y
G
D
V
--
P
--
L
I
--
S
V
E
T
L
Q
--
R
L
R
D
A
K
P
Q
G
G
I
G
L
L
T
V
K
L
D
D
P
T
G
Y
G
R
I
T
R
E
-
N
G
K
V
T
G
I
V
E
H
----
K
--
D
A
T
---------------------
D
E
Q
R
QIQE-----------------
I
N
T
G
I
L
I
A
N
G
A
D
M
K
R
W
--
L
A
K
L
T
N
N
N
A
Q
G
E
Y
Y
I
T
D
I
I
A
L
A
Y
Q
E
G
R
E
I
V
----------
A
V
-----------
H
-
P
--
Q
R
L
-
S
E
--------
V
E
G
V
N
N
R
L
Q
L
S
R
L
E
R
V
-
Y
Q
S
E
Q
-
A
E
---
K
-
L
L
-------
L
A
G
V
M
L
R
D
P
A
-
R
F
D
L
R
-
G
T
L
T
------
H
G
R
D
V
-------
E
I
D
-
T
N
V
I
I
E
G
-------
N
V
T
L
G
H
R
V
K
I
G
T
G
C
V
I
K
N
S
V
I
G
D
D
-------------------
C
E
-------------------
I
S
P
Y
T
V
V
E
D
-
A
N
L
A
A
A
C
T
I
G
P
F
-------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
53.38
28%
-82
- C2 -
4ARW
4
?
A:
[15-244]
--------
I
I
L
A
G
G
S
G
T
R
L
H
P
A
T
L
A
I
S
K
Q
L
L
P
V
Y
-
D
K
-
P
M
I
Y
Y
P
L
S
T
L
M
L
A
G
I
R
E
I
L
I
I
S
T
P
Q
D
T
P
R
F
Q
Q
L
L
G
D
G
S
N
W
G
L
D
-
L
-
Q
Y
A
V
---
Q
P
S
P
--------
D
G
L
A
Q
A
F
L
I
G
E
S
F
I
G
--
N
D
L
S
A
L
V
L
G
D
N
L
--
Y
Y
G
H
D
--
F
H
E
L
L
G
--
S
A
S
Q
R
Q
T
G
A
S
V
F
A
Y
H
V
--
L
D
P
E
R
Y
G
V
V
E
F
D
Q
G
G
K
A
I
S
L
E
E
K
----
P
--
L
E
P
---------------------
K
S
N
Y
---------------------
A
V
T
G
L
Y
F
Y
D
Q
Q
V
V
D
I
A
R
D
L
K
P
S
P
R
G
E
L
E
I
T
D
V
N
R
----
A
Y
L
E
R
G
Q
L
S
V
----------
E
I
-----------
M
-
G
--
R
G
Y
A
W
L
--------
D
T
G
T
H
D
S
L
L
E
A
G
Q
F
I
A
-
T
L
E
N
R
-
Q
G
---
L
-
K
V
-------
A
C
-
P
E
E
I
A
Y
R
-
Q
K
W
I
D
-
A
A
Q
L
------
E
K
L
A
A
P
----
L
A
K
N
G
-
Y
G
Q
Y
L
K
R
-
L
--
L
-
T
E
T
V
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------