@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0920: (2015-12-04 )
MIRRAKEKDLPAIAELLKQILVLHHGVRPDIFHTRGSKFSKEQLKEMLMDESRPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLMDFARQYAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------.........10........20..----------...--.--..30.------..-.....40........-50----.--...--.....60------.........70.......-------.80---------------.-........90...-.....100......-.110......-.120.-......130.......140.......150..------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------MIRRAKEK
D
L
P
A
I
A
E
L
L
K
Q
I
L
V
L
----------HHG--V--RPD
I
F
------HT-RGSKF
S
K
E
Q
L
K
E
M
L
M-D-----E--SR
P
--
I
F
V
Y
ES-------DE
G
K
V
V
A
H
L
F
L
Q
L
Q
E
KRD-------L
P
----------------
R
-
K
SF
K
T
L
Y
I
DDLCI-
D
E
E
V
R
G
Q
Q
I
G
Q
K
L
M
-
D
F
A
R
Q
Y
A
K
KH-G
C
Y
N
I
-
T
L
N
V
WND
N
Q
R
A
V
S
F
Y
E
K
LGFKPQ
Q
T
Q
M
E
EIL------------------
2
PsiBlast_PDB
91.44
30%
-129
- C2 -
4F6A
1
?
A:
[2-153]
----------------------------------------------------------------------------------------------------------------------------------------------------
I
I
R
E
A
T
V
Q
D
Y
Y
E
V
A
R
L
H
T
Q
V
H
E
A
----------
H
V
K
--
E
--
R
G
D
I
F
------
R
S
-
N
E
P
T
L
N
P
S
R
F
Q
A
A
V
Q
-
G
-----
E
--
K
S
T
--
V
L
V
F
V
D
-------
E
R
E
K
I
G
A
Y
S
V
I
H
L
V
Q
T
P
L
-------
L
P
----------------
T
M
Q
Q
R
K
T
V
Y
I
S
D
L
C
V
-
D
E
T
R
R
G
G
G
I
G
R
L
I
F
-
E
A
I
I
S
Y
G
K
A
H
-
Q
V
D
A
I
-
E
L
D
V
Y
D
F
N
E
R
A
K
R
F
Y
H
S
L
G
M
R
C
Q
K
Q
T
M
E
L
P
L
------------------
1
PsiBlast_PDB
86.93
30%
-126
- C2 -
4E0A
3
?
A:
[2-153]
----------------------------------------------------------------------------------------------------------------------------------------------------
I
I
R
E
A
T
V
Q
D
Y
E
E
V
A
R
L
H
T
Q
V
H
E
A
----------
H
V
K
--
E
--
R
G
D
I
F
------
R
S
-
N
E
P
T
L
N
P
S
R
F
Q
A
A
V
Q
-
G
-----
E
--
K
S
T
--
V
L
V
F
V
D
-------
E
R
E
K
I
G
A
Y
S
V
I
H
L
V
Q
T
P
L
-------
L
P
----------------
T
M
Q
Q
R
K
T
V
Y
I
S
D
L
C
V
-
D
E
T
R
R
G
G
G
I
G
R
L
I
F
-
E
A
I
I
S
Y
G
K
A
H
-
Q
V
D
A
I
-
E
L
D
V
Y
D
F
N
D
R
A
K
A
F
Y
H
S
L
G
M
R
C
Q
K
Q
T
M
E
L
P
L
------------------
9
PsiBlast_PDB
78.67
23%
-120
- C2 -
1I1D
5
GNA1_YEAST
A:
[11-158]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
R
R
M
E
E
G
D
L
E
Q
V
T
E
T
L
K
-
V
L
T
T
----------
V
G
T
--
I
--
T
P
E
S
F
C
K
L
I
K
Y
W
N
-
E
A
T
V
W
N
D
---
K
K
I
M
--------
Q
--
Y
N
P
--
M
V
I
V
D
K
-------
R
T
E
T
V
A
A
T
G
N
I
I
I
E
--
R
K
-------
I
I
----------------
H
-
E
L
G
L
C
G
H
I
E
D
I
A
V
-
N
S
K
Y
Q
G
Q
G
L
G
K
L
L
I
-
D
Q
L
V
T
I
G
F
D
Y
-
G
C
Y
K
I
-
I
L
D
C
---
D
E
K
N
V
K
F
Y
E
K
C
G
F
S
N
A
G
V
E
M
Q
I
R
K
------------------
8
PsiBlast_PDB
77.72
23%
-115
- C2 -
1I12
3
GNA1_YEAST
A:
[10-157]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
R
R
M
E
E
G
D
L
E
Q
V
T
E
T
L
K
-
V
L
T
T
----------
V
G
T
--
I
--
T
P
E
S
F
C
K
L
I
K
Y
W
N
-
E
A
T
V
W
N
D
---
K
K
I
M
--------
Q
--
Y
N
P
--
M
V
I
V
D
K
-------
R
T
E
T
V
A
A
T
G
N
I
I
I
E
--
R
K
-------
I
I
----------------
H
-
E
L
G
L
C
G
H
I
E
D
I
A
V
-
N
S
K
Y
Q
G
Q
G
L
G
K
L
L
I
-
D
Q
L
V
T
I
G
F
D
Y
-
G
C
Y
K
I
-
I
L
D
C
---
D
E
K
N
V
K
F
Y
E
K
C
G
F
S
N
A
G
V
E
M
Q
I
R
K
------------------
76
HHSearch
76.72
31%
-91
- C1 -
1U6M
2
?
A:
[3-174]
----------------------------------------------------------------------------------------------------------------------------------------------------
L
I
R
S
A
T
K
E
D
G
Q
A
I
A
R
L
V
L
V
I
L
K
D
----------
M
E
L
------
P
I
-
L
------
E
E
-
V
S
E
E
Q
M
I
D
L
L
A
E
A
T
A
-
Y
PTYRY
G
--
Y
Q
R
--
I
L
V
Y
E
H
--------
A
G
E
V
A
G
I
A
V
G
Y
P
A
E
D
E
K
IID
E
P
L
R
E
V
F
K
K
H
GLAEDVRLFIEE
E
-
T
L
P
N
E
W
Y
L
D
T
I
S
V
-
D
E
R
F
R
G
M
G
I
G
S
K
L
L
-
D
A
L
P
E
V
A
K
A
S
-
G
K
Q
A
L
-
G
L
N
V
D
F
D
N
P
G
A
R
K
L
Y
A
S
K
G
F
K
D
V
T
T
M
T
I
S
G
H
------------------
62
Fugue
75.95
27%
-134
- C1 -
2BEI
1
SAT2_HUMAN
A:
[3-169]
--------------------------------------------------------------------------------------------------------------------------------------------------S
V
R
I
R
E
A
K
E
G
D
C
G
D
I
L
R
L
I
R
E
L
A
E
F
----------
E
----------------------
K
L
K
I
S
E
E
A
L
R
A
D
G
F
-
G
-----
D
--
N
P
F
Y
H
C
L
V
A
E
I
-------
L
G
P
C
V
V
G
Y
G
I
Y
Y
F
I
Y
S
T
----------------------------
W
K
G
R
T
I
Y
L
E
D
I
Y
V
M
P
E
Y
-
R
G
Q
G
I
G
S
K
I
I
-
K
K
V
A
E
V
A
L
D
K
-
G
C
S
Q
F
-
R
L
A
V
L
D
W
N
Q
R
A
M
D
L
Y
K
A
L
G
A
Q
D
L
T
E
A
E
G
W
H
F
F
C
F
Q
G
E
A
T
R
K
L
A
G-----
74
HHSearch
72.96
24%
-101
- C1 -
1Z4E
-
?
A:
[6-152]
----------------------------------------------------------------------------------------------------------------------------------------------------
T
I
R
E
A
T
E
G
D
L
E
Q
M
V
H
M
L
A
D
D
V
L
G
----------
R
K
------
R
E
-
R
Y
------
E
K
-
P
L
P
V
S
Y
V
R
A
F
K
E
I
K
K
-
D
-----
K
--
N
N
E
--
L
I
V
A
C
N
--------
G
E
E
I
V
G
M
L
Q
V
T
F
T
P
Y
L
---------
T
----------------
Y
-
Q
G
S
W
R
A
T
I
E
G
V
R
T
-
H
S
A
A
R
G
Q
G
I
G
S
Q
L
V
-
C
W
A
I
E
R
A
K
E
R
-
G
C
H
L
I
-
Q
L
T
T
D
K
Q
R
P
D
A
L
R
F
Y
E
Q
L
G
F
K
A
S
H
E
G
L
K
M
H
F
------------------
73
HHSearch
71.57
21%
-108
- C1 -
1TIQ
4
PAIA_BACSU
A:
[4-152]
----------------------------------------------------------------------------------------------------------------------------------------------------
K
M
K
K
C
S
R
E
D
L
Q
T
L
Q
Q
L
S
I
E
T
F
N
D
----------
T
F
K
--
E
QN
S
P
E
N
M
------
K
A
Y
L
E
S
A
F
N
T
E
Q
L
E
K
E
L
S
-
N
-----
M
--
S
S
Q
--
F
F
F
I
Y
F
--------
D
H
E
I
A
G
Y
V
K
V
N
I
D
D
A
Q
S
--------
E
----------------
E
-
M
G
A
E
S
L
E
I
E
R
I
Y
I
-
K
N
S
F
Q
K
H
G
L
G
K
H
L
L
-
N
K
A
I
E
I
A
L
E
R
-
N
K
K
N
I
-
W
L
G
V
W
E
K
N
E
N
A
I
A
F
Y
K
K
M
G
F
V
Q
T
G
A
H
S
F
Y
M
G
------------------
69
HHSearch
71.22
25%
-109
- C1 -
2DXQ
6
?
A:
[7-148]
----------------------------------------------------------------------------------------------------------------------------------------------------
S
L
R
A
A
G
P
G
D
L
P
G
L
L
E
L
Y
Q
V
L
N
P
S
----------
D
--------
P
E
L
-----------
T
T
Q
E
A
G
A
V
F
A
A
M
L
A
-
Q
-----
P
--
G
L
T
--
I
F
V
A
T
E
--------
N
G
K
P
V
A
T
A
T
L
L
I
V
P
N
L
---------
T
----------------
R
-
A
A
R
P
Y
A
F
I
E
N
V
V
T
-
L
E
A
R
R
G
R
G
Y
G
R
T
V
V
-
R
H
A
I
E
T
A
F
G
A
-
N
C
Y
K
V
-
M
L
L
T
G
R
H
D
P
A
V
H
A
F
Y
E
S
C
G
F
V
Q
N
K
T
G
F
Q
I
R
Q
------------------
3
PsiBlast_PDB
70.96
28%
-123
- C1 -
3JVN
1
?
A:
[4-136]
----------------------------------------------------------------------------------------------------------------------------------------------------
V
I
R
R
A
K
E
I
D
L
Y
C
L
N
S
L
M
Y
K
L
H
D
E
----------
H
H
Q
--
Q
--
C
P
D
-----------------
E
K
S
I
A
R
Y
L
D
-
D
-----
P
--
E
C
M
--
V
Y
V
A
E
M
-------
D
D
-
V
I
I
G
F
I
T
G
H
F
C
E
L
I
S
-------
T
V
----------------
S
-
K
L
V
M
M
A
T
I
D
E
L
Y
I
-
E
K
E
Y
R
R
E
G
V
A
E
Q
L
M
-
M
R
I
E
Q
E
L
K
D
Y
-
G
V
K
E
I
-
F
V
E
V
W
--
N
K
G
A
--------------------------------------
82
HHSearch
70.28
24%
-119
- C1 -
3DSB
3
?
A:
[8-150]
----------------------------------------------------------------------------------------------------------------------------------------------------
E
I
R
E
A
R
M
D
D
L
D
T
I
A
K
F
N
Y
N
L
A
K
E
----------
T
E
G
--
K
-----
E
L
----------
D
M
D
V
L
T
K
G
V
K
A
L
L
L
-
D
-----
E
R-
K
G
K
--
Y
H
V
Y
T
V
--------
F
D
K
V
V
A
Q
I
M
Y
T
Y
E
W
S
D
--------------------------
W
-
R
N
G
N
F
L
W
I
Q
S
V
Y
V
-
D
K
E
Y
R
R
K
G
I
F
N
Y
L
F
-
N
Y
I
K
N
I
C
D
K
D
E
N
I
V
G
M
-
R
L
Y
V
E
K
E
N
I
N
A
K
A
T
Y
E
S
L
N
M
Y
E
C
D
Y
N
M
Y
E
Y
E
------------------
70
HHSearch
69.96
27%
-122
- C1 -
3JVN
1
?
A:
[4-136]
----------------------------------------------------------------------------------------------------------------------------------------------------
V
I
R
R
A
K
E
I
D
L
Y
C
L
N
S
L
M
Y
K
L
H
D
E
----------
H
H
Q
--
Q
--
C
P
D
-----------------
E
K
S
I
A
R
Y
L
D
-
D
-----
P
--
E
C
M
--
V
Y
V
A
E
M
--------
D
D
V
I
I
G
F
I
T
G
H
F
C
E
L
I
S
-------
T
V
----------------
S
-
K
L
V
M
M
A
T
I
D
E
L
Y
I
-
E
K
E
Y
R
R
E
G
V
A
E
Q
L
M
-
M
R
I
E
Q
E
L
K
D
Y
-
G
V
K
E
I
-
F
V
E
V
W
--
N
K
G
A
--------------------------------------
20
PsiBlast_PDB
69.40
26%
-95
* C2 *
2FE7
-
?
A:
[7-140]
--------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
V
P
A
D
A
E
Q
I
L
A
F
I
I
E
L
A
D
Y
E
RA
R
H
E
--
V
--
V
T
D
V
E
------
G
I
-
R
R
S
L
F
A
E
G
S
P
T
R
A
L
M
-
C
-----
L
--
S
------------------
E
G
R
P
I
G
Y
A
V
F
F
Y
S
Y
S
T
W
-------
L
G
----------------
R
-
N
G
---
I
Y
L
E
D
L
Y
V
-
T
P
E
Y
R
--
G
A
G
R
R
L
L
R
E
L
A
R
E
-
A
V
A
N
-
D
C
G
R
L
-
E
W
S
V
L
D
W
N
Q
P
A
I
D
F
Y
R
S
I
G
A
L
P
Q
D
E
W
V
R
Y
R
L
------------------
64
Fugue
69.33
22%
-109
- C1 -
2CY2
1
?
A:
[1-174]
---------------------------------------------------------------------------------------------------------------------------------------------------V
R
I
R
R
A
G
L
E
D
L
P
G
V
A
R
V
L
V
D
T
W
R
A
----------
T
Y
R
GV
V
--
P
E
A
F
L
------
E
G
-
L
S
Y
E
G
Q
A
E
R
W
A
Q
R
L
K
-
T
-----
P
--
T
W
P
G
R
L
F
V
A
E
S
-------
E
S
G
E
V
V
G
F
A
A
F
G
P
D
R
A
S
G
-------
F
P
----------------
G
-
Y
---
T
A
E
L
W
A
I
Y
V
-
L
P
T
W
Q
R
K
G
L
G
R
A
L
F
-
H
E
G
A
R
L
L
Q
A
E
-
G
-
Y
G
R
M
L
V
W
V
L
K
E
N
P
K
G
R
G
F
Y
E
H
L
G
G
V
L
L
G
E
R
E
I
E
L
G
G
A
K
L
W
E
V
A
Y
G
F
D
LGGHKW
66
Fugue
68.41
17%
-93
- C1 -
1P0H
2
MSHD_MYCTU
A:
[6-313]
A
L
D
W
R
SALT
A
D
E
Q
R
S
V
R
A
L
V
T
A
T
T
A
V
D
GVAPVG
E
Q
V
L
R
E
L
GQQR
T
E
H
L
L
V
A
G
SRPGGPII
G
Y
L
N
L
S
P
PG
G
A
M
A
E
L
V
V
HPQSRRRG
I
G
T
A
M
A
R
A
A
L
A
K
T
A
GR
N
Q
F
W
A
H
GTL
D
P
A
R
A
T
A
S
A
L
GLVGV
R
E
L
I
Q
M
R
R
P
LRD
I
P
E
P
T
I
P
D
G
V
V
I
R
T
Y
A
G
T
S
D
D
A
E
L
L
R
V
N
N
A
A
F
A
-----------------------
G
------
H
P
-
E
Q
G
G
W
T
A
V
Q
L
A
E
R
R
G
-
E
-----
A
WF
D
P
D
--
G
L
I
L
A
F
-------
G
D
G
R
L
L
G
F
H
W
T
K
V
H
P
D
H
P
------------------------------
G
L
G
E
V
Y
V
L
G
V
-
D
P
A
A
Q
R
R
G
L
G
Q
M
L
T
S
I
G
I
V
S
L
A
R
R
L
-
V
E
P
A
V
-
L
L
Y
V
E
S
D
N
V
A
A
V
R
T
Y
Q
S
L
G
F
T
T
Y
S
V
D
T
A
Y
A
L
------------------
85
HHSearch
68.33
20%
-116
* C1 *
2FE7
-
?
A:
[4-144]
----------------------------------------------------------------------------------------------------------------------------------------------------
E
I
R
P
A
V
P
A
D
A
E
Q
I
L
A
F
I
I
E
L
A
D
Y
----------
E
R
A
-----
R
H
E
V
V
---------
T
D
V
E
---
G
I
R
R
S
L
F
A
E
G
-----
S
--
P
T
R
--
A
L
M
C
L
S
--------
E
G
R
P
I
G
Y
A
V
F
F
Y
S
Y
S
T
---------
W
------------------
L
G
R
N
G
I
Y
L
E
D
L
Y
V
-
T
P
E
Y
R
--
G
A
G
R
R
L
L
-
R
E
L
A
R
E
A
V
A
N
-
D
C
G
R
L
-
E
W
S
V
L
D
W
N
Q
P
A
I
D
F
Y
R
S
I
G
A
L
P
Q
D
E
W
V
R
Y
R
L
------------------
63
Fugue
67.80
22%
-86
- C1 -
1I12
3
GNA1_YEAST
A:
[4-160]
-----------------------------------------------------------------------------------------------------------------------------------------------LPDG
F
Y
I
R
R
M
E
E
G
D
L
E
Q
V
T
E
T
L
K
V
L
T
T
V
----------
G
T
I
--
T
--
P
E
S
F
C
------
K
L
-
I
K
Y
W
N
E
A
T
V
W
N
D
K
K
I
-
M
-----
Q
--
Y
N
P
--
M
V
I
V
D
K
-------
R
T
E
T
V
A
A
T
G
N
I
I
I
E
R
K
---------
I
I
----------------
H
-
E
L
G
L
C
G
H
I
E
D
I
A
V
-
N
S
K
Y
Q
G
Q
G
L
G
K
L
L
I
-
D
Q
L
V
T
I
G
F
D
Y
-
G
C
Y
K
I
-
I
L
D
C
---
D
E
K
N
V
K
F
Y
E
K
C
G
F
S
N
A
G
V
E
M
Q
I
R
K
------------------
80
HHSearch
66.89
24%
-95
- C1 -
1VKC
8
?
A:
[11-157]
----------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
I
V
D
G
E
E
Y
I
E
E
I
K
K
L
D
R
E
I
S
Y
S
----------
F
V
R
--
F
---
P
I
S
Y
------
E
--
E
Y
E
E
R
H
E
E
L
F
E
S
L
L
S
-
Q
-----
G
--
E
H
K
--
F
F
V
A
L
N
-------
E
R
S
E
L
L
G
H
V
W
I
C
I
T
L
D
T
--------------------------
V
-
D
Y
V
K
I
A
Y
I
Y
D
I
E
V
-
V
K
W
A
R
G
L
G
I
G
S
A
L
L
-
R
K
A
E
E
W
A
K
E
R
-
G
A
K
K
I
-
V
L
R
V
E
I
D
N
-
P
A
V
K
W
Y
E
E
R
G
Y
K
A
R
A
L
I
M
E
K
P
I
------------------
83
HHSearch
66.88
20%
-115
- C1 -
2B5G
4
SAT1_HUMAN
A:
[5-150]
----------------------------------------------------------------------------------------------------------------------------------------------------
V
I
R
P
A
T
A
A
D
C
S
D
I
L
R
L
I
K
E
L
A
K
Y
--------------------
E
Q
V
-----------
I
L
T
E
K
D
L
L
E
D
G
F
G
-
E
H----
P
--
F
Y
H
--
C
L
V
A
E
V
P
KEHWTP
E
G
H
S
I
V
G
F
A
M
Y
Y
F
T
Y
D
P
---------
W
-------------------
I
G
K
L
L
Y
L
E
D
F
F
V
-
M
S
D
Y
R
G
F
G
I
G
S
E
I
L
-
K
N
L
S
Q
V
A
M
R
C
-
R
C
S
S
M
-
H
F
L
V
A
E
W
N
E
P
S
I
N
F
Y
K
R
R
G
A
S
D
L
S
S
E
E
G
W
R
L
------------------
75
HHSearch
66.88
22%
-98
- C1 -
2CY2
1
?
A:
[2-151]
----------------------------------------------------------------------------------------------------------------------------------------------------
R
I
R
R
A
G
L
E
D
L
P
G
V
A
R
V
L
V
D
T
W
R
A
----------
T
Y
R
G-
V
--
V
P
E
A
F
------
L
E
G
L
S
Y
E
G
Q
A
E
R
W
A
Q
R
L
K
-
T
-----
P
TW
P
G
R
--
L
F
V
A
E
S
-------
E
S
G
E
V
V
G
F
A
A
F
G
P
D
R
A
S
G
---------------------------
F
P
G
Y
T
A
E
L
W
A
I
Y
V
-
L
P
T
W
Q
R
K
G
L
G
R
A
L
F
-
H
E
G
A
R
L
L
Q
A
E
-
G
Y
G
R
M
-
L
V
W
V
L
K
E
N
P
K
G
R
G
F
Y
E
H
L
G
G
V
L
L
G
E
R
E
I
E
L
G
------------------