@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0930: (2015-12-04 )
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINQGYYGMVTGDIFPLDANSVGDTINRGGTFLRSARYPEFAELEGQLKGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGLPGTIDNDIVGTDYTIGFDTAVATAVENLDRLRDTSASHNRTFVVEVMGRNAGDIALWSGIAAGADQIIVPEEEFNIDEVVSNVRAGYAAGKHHQIIVLAEGVMSGDEFAKTMKAAGDDSDLRVTNLGHLLRGGSPTARDRVLASRMGAYAVQLLKEGRGGLAVGVHNEEMVESPILGLAEEGALFSLTDEGKIVVNNPHKADLRLAALNRDLANQSSK
Atome Classification :
(22 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230..-.....240.......250.......260.......270.......280.......290.......300-----.......310.......320.......330.......340
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
R
I
A
V
L
TSGGDAP
G
M
N
A
A
I
R
A
V
V
R
K
A
I
SEG
M
E
V
Y
GINQG
Y
Y
G
M
V
TG
D
I
F
PLDANSVGDTINRGGTFLRSARYP
E
F
A
E
L
E
G
Q
L
K
G
I
E
Q
L
K
KHGI
E
G
V
V
V
IGGDGSYHG
A
M
R
LTEHGFPAVGLPGTIDNDIVGT
D
Y
T
IG
F
D
T
A
V
A
T
A
V
E
N
L
D
R
L
RDTSASHN
R
T
F
V
V
E
V
MGRNAG
D
I
A
L
WSGIAAGA
D
Q
I
I
VPEEEF
N
I
D
E
V
V
S
N
V
R
A
GYAAGK
H
H
Q
I
I
V
L
AEGVMS
G
D
E
F
A
K
T
M
-
K
AAGDDSD
L
R
V
T
N
L
G
H
L
LRGGSP
T
A
R
D
R
V
L
A
S
R
M
G
A
Y
A
V
Q
L
L
K
EGRG
G
L
A
V
GVH
N
E
E
M
V
ESPILGLAE-----EG
A
L
F
S
LTDE
G
K
I
V
VNNPHKA
D
L
R
L
A
A
LN
R
D
L
ANQSSK
3
PsiBlast_PDB
97.26
57%
-104
- C6 -
3PFK
2
PFKA_GEOSE
A:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
Q
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
24
PsiBlast_CBE
97.24
57%
-105
- C6 -
3U39
2
PFKA_GEOSE
D:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
4
PsiBlast_PDB
97.00
57%
-105
- C6 -
4PFK
4
PFKA_GEOSE
A:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
Q
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
2
PsiBlast_PDB
96.94
57%
-106
- C6 -
3U39
1
PFKA_GEOSE
A:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
29
PsiBlast_CBE
96.78
57%
-105
- C6 -
4I4I
2
PFKA_GEOSE
B:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
A
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
10
PsiBlast_PDB
96.74
58%
-106
- C6 -
4A3S
-
PFKA_BACSU
A:
[1-316]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
V
R
A
V
V
R
K
A
I
Y
H
D
V
E
V
Y
G
I
Y
N
G
Y
A
G
L
I
S
G
K
I
E
K
L
E
L
G
S
V
G
D
I
I
H
R
G
G
T
K
L
Y
T
A
R
C
P
E
F
K
T
V
E
G
R
E
K
G
I
A
N
L
K
K
L
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
M
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
A
G
L
A
G
G
A
E
S
I
L
I
P
E
A
D
Y
D
M
H
E
I
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
E
F
G
K
R
I
-
E
E
E
-
T
N
L
E
T
R
V
S
V
L
G
H
I
Q
R
G
G
S
P
S
A
A
D
R
V
L
A
S
R
L
G
A
Y
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
K
L
V
D
H
D
I
I
E
I
L
E
T
K
H
T
V
E
Q
N
M
Y
Q
L
S
K
E
L
S
I
-------------------------
12
PsiBlast_PDB
96.70
57%
-112
- C6 -
2PFK
-
PFKA_ECOLI
A:
[1-300]
I
K
K
I
G
V
L
T
S
G
G
D
A
P
G
M
N
A
A
I
R
G
V
V
R
S
A
L
T
E
G
L
E
V
M
G
I
Y
D
G
Y
L
G
L
Y
E
D
R
M
V
Q
L
D
R
Y
S
V
S
D
M
I
N
R
G
G
T
F
L
G
S
A
R
F
P
E
F
R
D
E
N
I
R
A
V
A
I
E
N
L
K
K
R
G
I
D
A
L
V
V
I
G
G
D
G
S
Y
M
G
A
M
R
L
T
E
M
G
F
P
C
I
G
L
P
G
T
I
D
N
D
I
K
G
T
D
Y
T
I
G
F
F
T
A
L
S
T
V
V
E
A
I
D
R
L
R
D
T
S
S
S
H
Q
R
I
S
V
V
E
V
M
G
R
Y
C
G
D
L
T
L
A
A
A
I
A
G
G
C
E
F
V
V
V
P
E
V
E
F
S
R
E
D
L
V
N
E
I
K
A
G
I
A
K
G
K
K
H
A
I
V
A
I
T
E
H
M
C
D
V
D
E
L
A
H
F
I
E
K
E
T
G
R
E
T
--
R
A
T
V
L
G
H
I
Q
R
G
G
S
P
V
P
Y
D
R
I
L
A
S
R
M
G
A
Y
A
I
D
L
L
L
A
G
Y
G
G
R
C
V
G
I
Q
N
E
Q
L
V
H
H
D
I
I
D
A
I
--------------------------------------------
26
PsiBlast_CBE
96.59
57%
-104
- C6 -
3U39
2
PFKA_GEOSE
B:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
-----
21
PsiBlast_CBE
96.47
57%
-103
- C6 -
6PFK
2
PFKA_GEOSE
D:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
8
PsiBlast_PDB
96.31
57%
-105
- C6 -
1MTO
2
PFKA_GEOSE
A:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
W
V
I
E
V
M
G
R
H
A
G
D
I
A
L
Y
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
27
PsiBlast_CBE
96.29
57%
-105
- C6 -
4I4I
2
PFKA_GEOSE
D:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
A
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
23
PsiBlast_CBE
96.27
57%
-102
- C6 -
6PFK
2
PFKA_GEOSE
B:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
1
PsiBlast_PDB
96.12
57%
-103
- C6 -
6PFK
2
PFKA_GEOSE
A:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
80
HHSearch
96.11
54%
-103
* C6 *
1PFK
6
PFKA_ECOLI
A:
[2-320]
I
K
K
I
G
V
L
T
S
G
G
D
A
P
G
M
N
A
A
I
R
G
V
V
R
S
A
L
T
E
G
L
E
V
M
G
I
Y
D
G
Y
L
G
L
Y
E
D
R
M
V
Q
L
D
R
Y
S
V
S
D
M
I
N
R
G
G
T
F
L
G
S
A
R
F
P
E
F
R
D
E
N
I
R
A
V
A
I
E
N
L
K
K
R
G
I
D
A
L
V
V
I
G
G
D
G
S
Y
M
G
A
M
R
L
T
E
M
G
F
P
C
I
G
L
P
G
T
I
D
N
D
I
K
G
T
D
Y
T
I
G
F
F
T
A
L
S
T
V
V
E
A
I
D
R
L
R
D
T
S
S
S
H
Q
R
I
S
V
V
E
V
M
G
R
Y
C
G
D
L
T
L
A
A
A
I
A
G
G
C
E
F
V
V
V
P
E
V
E
F
S
R
E
D
L
V
N
E
I
K
A
G
I
A
K
G
K
K
H
A
I
V
A
I
T
E
H
M
C
D
V
D
E
L
A
H
F
I
-
E
K
E
T
-
G
R
E
T
R
A
T
V
L
G
H
I
Q
R
G
G
S
P
V
P
Y
D
R
I
L
A
S
R
M
G
A
Y
A
I
D
L
L
L
A
G
Y
G
G
R
C
V
G
I
Q
N
E
Q
L
V
H
H
D
I
I
D
A
I
E
-----
N
---------------
M
K
R
P
F
K
G
D
W
L
D
C
A
K
K
L
Y
-----
28
PsiBlast_CBE
96.08
57%
-102
- C6 -
4I4I
2
PFKA_GEOSE
C:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
A
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
31
PsiBlast_CBE
95.88
57%
-104
- C6 -
4I7E
2
PFKA_GEOSE
C:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
A
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
22
PsiBlast_CBE
95.83
57%
-106
- C6 -
6PFK
2
PFKA_GEOSE
C:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
9
PsiBlast_PDB
95.80
55%
-103
- C6 -
1ZXX
2
PFKA_LACDE
A:
[1-318]
M
K
R
I
G
I
L
T
S
G
G
D
A
P
G
M
N
A
A
V
R
A
V
T
R
V
A
I
A
N
G
L
E
V
F
G
I
R
Y
G
F
A
G
L
V
A
G
D
I
F
P
L
E
S
E
D
V
A
H
L
I
N
V
S
G
T
F
L
Y
S
A
R
Y
P
E
F
A
E
E
E
G
Q
L
A
G
I
E
Q
L
K
K
H
G
I
D
A
V
V
V
I
G
G
D
G
S
Y
H
G
A
L
Q
L
T
R
H
G
F
N
S
I
G
L
P
G
T
I
D
N
D
I
P
Y
T
D
A
T
I
G
Y
D
T
A
C
M
T
A
M
D
A
I
D
K
I
R
D
T
A
S
S
H
H
R
V
F
I
V
N
V
M
G
R
N
C
G
D
I
A
M
R
V
G
V
A
C
G
A
D
A
I
V
I
P
E
R
P
Y
D
V
E
E
I
A
N
R
L
K
Q
A
Q
E
S
G
K
D
H
G
L
V
V
V
A
E
G
V
M
T
A
D
Q
F
M
A
E
L
-
K
K
Y
G
-
D
F
D
V
R
A
N
V
L
G
H
M
Q
R
G
G
T
P
T
V
S
D
R
V
L
A
S
K
L
G
S
E
A
V
H
L
L
L
E
G
K
G
G
L
A
V
G
I
E
N
G
K
V
T
S
H
D
I
L
D
L
F
D
-----
E
----------------
S
H
R
G
D
Y
D
L
L
K
L
N
A
D
L
S
R
----
30
PsiBlast_CBE
95.73
57%
-104
- C6 -
4I7E
2
PFKA_GEOSE
D:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
A
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
T
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
5
PsiBlast_PDB
95.73
57%
-101
- C6 -
4I4I
2
PFKA_GEOSE
A:
[1-318]
M
K
R
I
G
V
L
T
S
G
G
D
S
P
G
M
N
A
A
I
R
S
V
V
R
K
A
I
Y
H
G
V
E
V
Y
G
V
Y
H
G
Y
A
G
L
I
A
G
N
I
K
K
L
E
V
G
D
V
G
D
I
I
H
R
G
G
T
I
L
Y
T
A
R
C
P
E
F
K
T
E
E
G
Q
K
K
G
I
E
Q
L
K
K
H
G
I
E
G
L
V
V
I
G
G
D
G
S
Y
Q
G
A
K
K
L
T
E
H
G
F
P
C
V
G
V
P
G
T
I
D
N
D
I
P
G
T
D
F
T
I
G
F
D
T
A
L
N
T
V
I
D
A
I
D
K
I
R
D
A
A
T
S
H
E
R
T
Y
V
I
E
V
M
G
R
H
A
G
D
I
A
L
W
S
G
L
A
G
G
A
E
T
I
L
I
P
E
A
D
Y
D
M
N
D
V
I
A
R
L
K
R
G
H
E
R
G
K
K
H
S
I
I
I
V
A
E
G
V
G
S
G
V
D
F
G
R
Q
I
-
Q
E
A
-
T
G
F
E
T
R
V
T
V
L
G
H
V
Q
R
G
G
S
P
T
A
F
D
R
V
L
A
S
R
L
G
A
R
A
V
E
L
L
L
E
G
K
G
G
R
C
V
G
I
Q
N
N
Q
L
V
D
H
D
I
---
A
E
------------------
A
L
A
N
K
H
T
I
D
Q
R
M
Y
A
L
S
K
E
L
S
I
----
11
PsiBlast_PDB
95.43
57%
-107
- C6 -
1PFK
6
PFKA_ECOLI
A:
[2-302]
I
K
K
I
G
V
L
T
S
G
G
D
A
P
G
M
N
A
A
I
R
G
V
V
R
S
A
L
T
E
G
L
E
V
M
G
I
Y
D
G
Y
L
G
L
Y
E
D
R
M
V
Q
L
D
R
Y
S
V
S
D
M
I
N
R
G
G
T
F
L
G
S
A
R
F
P
E
F
R
D
E
N
I
R
A
V
A
I
E
N
L
K
K
R
G
I
D
A
L
V
V
I
G
G
D
G
S
Y
M
G
A
M
R
L
T
E
M
G
F
P
C
I
G
L
P
G
T
I
D
N
D
I
K
G
T
D
Y
T
I
G
F
F
T
A
L
S
T
V
V
E
A
I
D
R
L
R
D
T
S
S
S
H
Q
R
I
S
V
V
E
V
M
G
R
Y
C
G
D
L
T
L
A
A
A
I
A
G
G
C
E
F
V
V
V
P
E
V
E
F
S
R
E
D
L
V
N
E
I
K
A
G
I
A
K
G
K
K
H
A
I
V
A
I
T
E
H
M
C
D
V
D
E
L
A
H
F
I
E
K
E
T
G
R
E
T
--
R
A
T
V
L
G
H
I
Q
R
G
G
S
P
V
P
Y
D
R
I
L
A
S
R
M
G
A
Y
A
I
D
L
L
L
A
G
Y
G
G
R
C
V
G
I
Q
N
E
Q
L
V
H
H
D
I
I
D
A
I
E
-----
N
M
K
R
P
F
K
G
D
W
L
D
C
A
K
K
L
Y
--------------------
40
PsiBlast_CBE
95.24
57%
-108
- C6 -
1PFK
6
PFKA_ECOLI
B:
[2-302]
I
K
K
I
G
V
L
T
S
G
G
D
A
P
G
M
N
A
A
I
R
G
V
V
R
S
A
L
T
E
G
L
E
V
M
G
I
Y
D
G
Y
L
G
L
Y
E
D
R
M
V
Q
L
D
R
Y
S
V
S
D
M
I
N
R
G
G
T
F
L
G
S
A
R
F
P
E
F
R
D
E
N
I
R
A
V
A
I
E
N
L
K
K
R
G
I
D
A
L
V
V
I
G
G
D
G
S
Y
M
G
A
M
R
L
T
E
M
G
F
P
C
I
G
L
P
G
T
I
D
N
D
I
K
G
T
D
Y
T
I
G
F
F
T
A
L
S
T
V
V
E
A
I
D
R
L
R
D
T
S
S
S
H
Q
R
I
S
V
V
E
V
M
G
R
Y
C
G
D
L
T
L
A
A
A
I
A
G
G
C
E
F
V
V
V
P
E
V
E
F
S
R
E
D
L
V
N
E
I
K
A
G
I
A
K
G
K
K
H
A
I
V
A
I
T
E
H
M
C
D
V
D
E
L
A
H
F
I
E
K
E
T
G
R
E
T
--
R
A
T
V
L
G
H
I
Q
R
G
G
S
P
V
P
Y
D
R
I
L
A
S
R
M
G
A
Y
A
I
D
L
L
L
A
G
Y
G
G
R
C
V
G
I
Q
N
E
Q
L
V
H
H
D
I
I
D
A
I
E
-----
N
M
K
R
P
F
K
G
D
W
L
D
C
A
K
K
L
Y
--------------------