@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1043: (2015-12-05 )
MIQINNLHKFYGQKEILKDINISIPKGKVTAILGPNGSGKSTLLSCISRLEPYDNGEIFLDKVPLAHYSSNDLAKTLAILRQSNHLTLKIKVRDLIGFGRFPYSKGRLSQKDKAVIESVISYMDLNDIADEFINNLSGGQIQRAFIAMTMAQDTQYICLDEPLNNLDMKYAVQMMDLIKRYAYEFNKTIVIIIHDINFATHYADNVVALKEGQVVSCGTVEDVMQEKILSHLFDMPIRIETVDGKSIILFCTT
Atome Classification :
(20 SA)
---.........10-..-......20........30........40........50........60....--..--.--.70-.........80....-....90........100.......110-.......120.......130.......140.......150...------....160.......170.......180.......190.......200.......210.......220...----....230.......240.......250.----------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MIQIN
N
L
H
K
F
Y
-
G
Q
-
K
E
I
L
K
D
INISIPKG
K
V
T
A
I
LGPNGS
G
K
S
T
L
L
S
C
I
S
RLEPYDNG
E
I
F
L
DKVPL--AH--Y--SS--
N
D
L
A
K
T
L
A
I
L
RQSN
H
-
L
T
L
K
I
K
V
R
D
LIGFGRFPYSKGRLS
Q
K
D
-
K
A
V
I
E
S
V
I
S
Y
M
D
L
N
D
I
A
D
E
F
I
N
NLSGGQ
I
Q
R
A
F
I
A
M
T
MAQD
T
Q
------
Y
I
CLDEPLNNL
D
M
K
Y
A
V
Q
M
M
D
L
I
K
R
Y
A
Y
EFN
K
T
I
V
I
I
I
HDIN
F
A
T
HYAD
N
V
V
A
LKEG
Q
V
V
SCG
T
V
E
D
V
M
Q
----
E
K
I
L
S
H
LFDM
P
I
R
I
E
TVDG
K
S
I
I
L
F
CTT----------------------------------------------------------------------------------------
26
PsiBlast_CBE
83.58
31%
-134
- C1 -
2OLK
1
?
D:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
NL
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
2
PsiBlast_PDB
82.96
31%
-136
- C1 -
2OLJ
4
?
A:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
4
PsiBlast_PDB
82.72
31%
-135
- C1 -
2OUK
1
?
A:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
1
PsiBlast_PDB
82.70
30%
-139
- C1 -
4G1U
1
HMUV_YERPE
C:
[11-246]
---
L
L
E
A
S
H
L
H
Y
H
V
-
Q
Q
-
Q
A
L
I
N
D
V
S
L
H
I
A
S
G
E
M
V
A
I
I
G
P
N
G
A
G
K
S
T
L
L
R
L
L
T
G
Y
L
S
P
S
H
G
E
C
H
L
L
G
Q
N
L
--
N
S
--
W
--
Q
P
--
K
A
L
A
R
T
R
A
V
M
R
Q
Y
S
E
-
L
A
F
P
F
S
V
S
E
V
I
Q
M
G
R
A
P
Y
G
----
G
S
Q
D
-
R
Q
A
L
Q
Q
V
M
A
Q
T
D
C
L
A
L
A
Q
R
D
Y
R
V
L
S
G
G
E
Q
Q
R
V
Q
L
A
R
V
L
A
Q
L
W
Q
PQP
T
P
R
W
L
F
L
D
E
P
T
S
A
L
D
L
Y
H
Q
Q
H
T
L
R
L
L
R
Q
L
T
R
Q
E
P
L
A
V
C
C
V
L
H
D
L
N
L
A
A
L
Y
A
D
R
I
M
L
L
A
Q
G
K
L
V
A
C
G
T
P
E
E
V
L
N
----
A
E
T
L
T
Q
W
Y
Q
A
D
L
G
V
S
R
H
P
E
S
A
L
P
Q
I
Y
L
R
----------------------------------------------------------------------------------------
21
PsiBlast_CBE
82.65
31%
-141
- C1 -
3C4J
4
?
B:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
NL
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
24
PsiBlast_CBE
82.54
31%
-133
- C1 -
2OUK
1
?
C:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
NL
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
25
PsiBlast_CBE
82.50
31%
-135
- C1 -
2OUK
1
?
B:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
27
PsiBlast_CBE
82.30
31%
-133
- C1 -
2OLK
1
?
C:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
NL
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
7
PsiBlast_PDB
82.15
31%
-132
- C1 -
3C41
3
?
J:
[3-229]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
NL
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
3
PsiBlast_PDB
81.81
31%
-137
- C1 -
2OLK
1
?
A:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
23
PsiBlast_CBE
81.71
31%
-135
- C1 -
2OUK
1
?
D:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
NL
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
84
HHSearch
81.67
31%
-138
* C1 *
2OLJ
4
?
A:
[24-251]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
KD
T
--
N
L
--
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
-
W
P
R
E
K
A
-
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
-
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
----
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
-----------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
81.59
31%
-136
- C1 -
3C4J
3
?
A:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
28
PsiBlast_CBE
81.53
31%
-132
- C1 -
2OLK
2
?
B:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
NL
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
94
Fugue
81.37
26%
-128
- C1 -
1Z47
1
?
A:
[11-355]
GSM
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
-
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
--
T
D
--
L
--
P
P
--
Q
K
--
R
N
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
L
R
E
--
K
R
V
P
K
D
E
M
-
D
A
R
V
R
E
L
L
R
F
M
R
L
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
------
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
KPGT
L
F
V
A
S
F
I
G
E
S
N
V
W
T
R
A
V
Q
N
G
R
I
E
V
A
G
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
29
PsiBlast_CBE
80.62
31%
-132
- C1 -
2OLJ
3
?
B:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
NL
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
81
HHSearch
79.45
29%
-131
- C1 -
3GFO
1
ECFA3_CLOP1
A:
[7-236]
---
I
L
K
V
E
E
L
N
Y
N
Y
-
S
D
G
T
H
A
L
K
G
I
N
M
N
I
K
R
G
E
V
T
A
I
L
G
G
N
G
V
G
K
S
T
L
F
Q
N
F
N
G
I
L
K
P
S
S
G
R
I
L
F
D
N
K
P
I
--
D
Y
--
S
R
K
G
I
--
M
K
L
R
E
S
I
G
I
V
F
Q
D
P
D
N
Q
L
F
S
A
S
V
Y
Q
D
V
S
F
G
A
V
N
M
K
L
--
P
E
D
E
I
-
R
K
R
V
D
N
A
L
K
R
T
G
I
E
H
L
K
D
K
P
T
H
C
L
S
F
G
Q
K
K
R
V
A
I
A
G
V
L
V
M
E
P
K
------
V
L
I
L
D
E
P
T
A
G
L
D
P
M
G
V
S
E
I
M
K
L
L
V
E
M
Q
K
E
L
G
I
T
I
I
I
A
T
H
D
I
D
I
V
P
L
Y
C
D
N
V
F
V
M
K
E
G
R
V
I
L
Q
G
N
P
K
E
V
F
A
----
E
K
E
V
I
R
K
V
N
L
R
L
P
R
I
G
H
L
M
E
I
-----------------------------------------------------------------------------------------------
5
PsiBlast_PDB
79.42
31%
-133
- C1 -
2Q0H
4
?
A:
[24-250]
---
M
I
D
V
H
Q
L
K
K
S
F
-
G
S
-
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--
K
A
--
K
--
D
T
N
L
N
K
V
R
E
E
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
-
A
K
A
M
E
-
L
L
D
K
V
G
L
K
D
K
A
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
-------------
L
F
D
R
P
Q
H
E
R
T
K
A
F
L
S
K
V
F
--------------------------------------------------------------------------------------------
14
PsiBlast_PDB
79.33
30%
-132
- C1 -
4YMW
-
?
J:
[1-223]
---
M
I
F
V
N
D
V
Y
K
N
F
-
G
S
-
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
NN
G
K
--
V
--
N
I
--
N
K
V
R
Q
K
V
G
M
V
F
Q
--
H
-
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
------
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
----
R
A
K
N
E
R
T
R
E
F
L
S
K
I
L
-----------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
78.63
29%
-132
- C1 -
4U00
3
?
A:
[4-225]
---
I
I
R
I
R
N
L
H
K
W
F
-
G
P
-
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
--
K
D
--
D
--
R
A
L
-
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
-
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
R
V
R
R
W
P
R
E
K
A
E
-
K
K
A
L
E
-
L
L
E
R
V
G
I
L
D
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
------
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
-
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
F
T
----
R
P
K
E
E
R
T
R
S
F
L
Q
R
V
L
H
----------------------------------------------------------------------------------------------------