@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1048: (2015-12-05 )
MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPMLTKIVGDKPKLMILNKADLADPIRTKEWRDFYESQGLKTLAINSKEQSTVKKVTDIAKILMSDKIAKLRGRGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQWLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKTYYPDRLKERFKSINLEDEAPEIIMALTQKLGYRDDYDRFYNLFVKEVRDGKLGRYTLDIVGEHDGNN
Atome Classification :
(20 SA)
----------------------------------------.........10--....-....20-........30........40.....-..---.-----50--........60.......----.----70.......--.---80--.---........90.....-...100.......110.......120.......130.......140..-----.------.----.-----..150....---...160--...----...-...170.......180.......----190.......200...-----------.-----.---..------------210.......220....-...230.......240......-----.250-------..---------.......260.......270...---..------..280.-----------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------M
A
T
I
Q
WFPG
H
M
--
S
K
A
R
-
R
Q
V
Q
E
N-IKH
V
D
F
V
T
I
L
V
DARLPLSSQN
P
M
L
T
-
K
I---V-----GD--KP
K
L
M
I
L
NKADLADPI
R
----
T
----
K
E
W
R
D
F
Y
E
S--Q---G---
L
---
K
T
L
A
INS
K
E
Q
S
T
V
K
K
-
V
T
D
I
A
K
I
L
M
SD
K
I
A
K
L
RGRGI
Q
K
E
T
L
R
T
M
I
I
GIPNA
G
K
S
T
L
M
N
R
LAG
K
-----
K
------
I
----
A
-----
V
VGNKPGV
T
---
K
G
Q
Q
----
W
L
K----SNK-
E
L
E
I
LDTPGILWPKFEDEL
V
G
L
K
----
L
A
L
TGAIKDQLLPMD
E
-----------
V
-----
T
---
I
F
------------
G
L
N
Y
F
K
T
YY
P
D
R
L
K
E
R
F
-
K
SINLEDEA
P
E
I
I
M
A
L
T
Q
KLGY-----RD---------
D
Y
---------
D
R
F
Y
N
L
F
V
K
E
VRDGKL
G
R
Y
T
L
D
I
---
V
G------EHDGNN-----------------------------------------------------------
105
HHSearch
96.60
47%
-93
- C14 -
1PUJ
2
RBGA_BACSU
A:
[9-281]
-------------------------------------------------
H
M
--
A
K
A
R
-
R
E
V
T
E
K
-
L
K
L
I
D
I
V
Y
E
L
V
D
A
R
I
P
M
S
S
R
N
P
M
I
E
-
D
I
---
L
-----
K
N
--
K
P
R
I
M
L
L
N
K
A
D
K
A
D
A
A
V
----
T
----
Q
Q
W
K
E
H
F
E
N
--
Q
---
G
---
I
---
R
S
L
S
I
N
S
V
N
G
Q
G
L
N
Q
-
I
V
P
A
S
K
E
I
L
Q
E
K
F
D
R
M
R
A
K
G
V
K
P
R
A
I
R
A
L
I
I
G
I
P
N
V
G
K
S
T
L
I
N
R
L
A
K
K
-----
N
------
I
----
A
--------------------
Q
----
W
V
K
----
V
G
K
-
E
L
E
L
L
D
T
P
G
I
L
W
P
K
F
E
D
E
L
V
G
L
R
----
L
A
V
T
G
A
I
K
D
S
I
I
N
L
Q
D
-----------
V
-----
A
---
V
F
------------
G
L
R
F
L
E
E
H
Y
P
E
R
L
K
E
R
Y
-
G
L
D
E
I
P
E
D
I
A
E
L
F
D
A
I
G
E
K
R
G
C
LMSGG
L
I
---------
N
Y
---------
D
K
T
T
E
V
I
I
R
D
I
R
T
E
K
F
G
R
L
S
F
E
Q
---
P
T
-----------------------------------------------------------------------
128
Fugue
96.30
46%
-94
- C14 -
1PUJ
2
RBGA_BACSU
A:
[9-281]
-------------------------------------------------
H
M
--
A
K
A
R
-
R
E
V
T
E
K
-
L
K
L
I
D
I
V
Y
E
L
V
D
A
R
I
P
M
S
S
R
N
P
M
I
E
-
D
I
---
L
-----
K
N
--
K
P
R
I
M
L
L
N
K
A
D
K
A
D
A
A
V
----
T
----
Q
Q
W
K
E
H
F
E
N
--
Q
---
G
---
I
---
R
S
L
S
I
N
S
V
N
G
Q
G
L
N
Q
-
I
V
P
A
S
K
E
I
L
Q
E
K
F
D
R
M
R
A
K
G
V
K
P
R
A
I
R
A
L
I
I
G
I
P
N
V
G
K
S
T
L
I
N
R
L
A
K
K
-----
N
------
I
----
A
--------------------
Q
----
W
V
K
----
V
G
K
-
E
L
E
L
L
D
T
P
G
I
L
W
P
K
F
E
D
E
L
V
G
L
R
----
L
A
V
T
G
A
I
K
D
S
I
I
N
L
Q
D
-----------
V
-----
A
---
V
F
------------
G
L
R
F
L
E
E
H
Y
P
E
R
L
K
E
R
Y
-
G
L
D
E
I
P
E
D
I
A
E
L
F
D
A
I
G
E
K
R
G
C
-----
L
M
SGGLI----
N
Y
---------
D
K
T
T
E
V
I
I
R
D
I
R
T
E
K
F
G
R
L
S
F
E
Q
---
P
T
-----------------------------------------------------------------------
1
PsiBlast_PDB
94.46
47%
-90
- C14 -
1PUJ
2
RBGA_BACSU
A:
[9-278]
-------------------------------------------------
H
M
--
A
K
A
R
-
R
E
V
T
E
K
-
L
K
L
I
D
I
V
Y
E
L
V
D
A
R
I
P
M
S
S
R
N
P
M
I
E
-
D
I
---
L
-----
K
N
--
K
P
R
I
M
L
L
N
K
A
D
K
A
D
A
A
V
----
T
----
Q
Q
W
K
E
H
F
E
N
--
Q
---
G
---
I
---
R
S
L
S
I
N
S
V
N
G
Q
G
L
N
Q
-
I
V
P
A
S
K
E
I
L
Q
E
K
F
D
R
M
R
A
K
G
V
K
P
R
A
I
R
A
L
I
I
G
I
P
N
V
G
K
S
T
L
I
N
R
L
A
K
K
-----
N
------
I
----
A
--------------------
Q
----
W
V
K
----
V
G
K
-
E
L
E
L
L
D
T
P
G
I
L
W
P
K
F
E
D
E
L
V
G
L
R
----
L
A
V
T
G
A
I
K
D
S
I
I
N
L
Q
D
-----------
V
-----
A
---
V
F
------------
G
L
R
F
L
E
E
H
Y
P
E
R
L
K
E
R
Y
-
G
L
----
D
E
I
P
E
D
I
A
E
L
F
D
A
I
G
E
-----
K
R
GCLMSGGLI
N
Y
---------
D
K
T
T
E
V
I
I
R
D
I
R
T
E
K
F
G
R
L
S
F
E
Q
---
P
T
-----------------------------------------------------------------------
4
PsiBlast_PDB
77.74
32%
-87
- C14 -
3CNO
1
RBGA_THEMA
A:
[13-246]
----------------------------------------------------------
R
Q
I
K
D
L
-
L
R
L
V
N
T
V
V
E
V
R
D
A
R
A
P
F
A
T
S
A
Y
G
V
D
------
F
-----
S
R
--
K
E
T
I
I
L
L
N
K
V
D
I
A
D
E
K
T
----
T
----
K
K
W
V
E
F
F
K
K
--
Q
---
G
---
K
---
R
V
I
T
T
H
K
G
E
P
R
K
V
------
L
L
K
K
L
S
F
D
R
L
A
------------
R
V
L
I
V
G
V
P
N
T
G
K
S
T
I
I
N
K
L
K
G
K
-----
R
------
A
-----------------------
G
I
Q
----
W
F
S
----
L
E
N
-
G
V
K
I
L
D
T
P
G
I
L
Y
K
N
I
F
S
E
D
L
A
A
K
----
L
L
L
V
G
S
-----
L
P
V
E
R
-----------
I
-----
E
D
Q
R
I
F
----------------------
E
R
A
F
E
I
F
A
R
S
I
G
I
E
S
S
F
S
E
F
F
E
D
F
A
R
K
R
G
L
-----
L
K
KGGVP----
D
I
---------
E
R
A
L
M
L
F
F
T
E
V
A
Q
G
K
A
G
R
V
S
F
E
R
---
P
E
------
D
----------------------------------------------------------------
3
PsiBlast_PDB
77.19
32%
-88
- C14 -
3CNN
1
RBGA_THEMA
A:
[13-246]
----------------------------------------------------------
R
Q
I
K
D
L
-
L
R
L
V
N
T
V
V
E
V
R
D
A
R
A
P
F
A
T
S
A
Y
G
V
D
------
F
-----
S
R
--
K
E
T
I
I
L
L
N
K
V
D
I
A
D
E
K
T
----
T
----
K
K
W
V
E
F
F
K
K
--
Q
---
G
---
K
---
R
V
I
T
T
H
K
G
E
P
R
K
V
------
L
L
K
K
L
S
F
D
R
L
A
------------
R
V
L
I
V
G
V
P
N
T
G
K
S
T
I
I
N
K
L
K
G
K
-----
R
------
A
-----------------------
G
I
Q
----
W
F
S
----
L
E
N
-
G
V
K
I
L
D
T
P
G
I
L
Y
K
N
I
F
S
E
D
L
A
A
K
----
L
L
L
V
G
S
-----
L
P
V
E
R
-----------
I
-----
E
D
Q
R
I
F
----------------------
E
R
A
F
E
I
F
A
R
S
I
G
I
E
S
S
F
S
E
F
F
E
D
F
A
R
K
R
G
L
-----
L
K
KGGVP----
D
I
---------
E
R
A
L
M
L
F
F
T
E
V
A
Q
G
K
A
G
R
V
S
F
E
R
---
P
E
------
D
----------------------------------------------------------------
2
PsiBlast_PDB
77.07
32%
-83
- C14 -
3CNL
1
RBGA_THEMA
A:
[9-246]
-----------------------------------------------------
E
K
A
K
-
R
Q
I
K
D
L
-
L
R
L
V
N
T
V
V
E
V
R
D
A
R
A
P
F
A
T
S
A
Y
G
V
D
------
F
-----
S
R
--
K
E
T
I
I
L
L
N
K
V
D
I
A
D
E
K
T
----
T
----
K
K
W
V
E
F
F
K
K
--
Q
---
G
---
K
---
R
V
I
T
T
H
K
G
E
P
R
K
V
------
L
L
K
K
L
S
F
D
R
L
A
------------
R
V
L
I
V
G
V
P
N
T
G
K
S
T
I
I
N
K
L
K
G
K
-----
R
------
A
----------------------
K
G
I
Q
----
W
F
S
----
L
E
N
-
G
V
K
I
L
D
T
P
G
I
L
Y
K
N
I
F
S
E
D
L
A
A
K
----
L
L
L
V
G
S
-----
L
P
V
E
R
-----------
I
-----
E
D
Q
R
I
F
----------------------
E
R
A
F
E
I
F
A
R
S
I
G
I
E
S
S
F
S
E
F
F
E
D
F
A
R
K
R
G
L
-----
L
K
KGGVP----
D
I
---------
E
R
A
L
M
L
F
F
T
E
V
A
Q
G
K
A
G
R
V
S
F
E
R
---
P
E
------
D
I
---------------------------------------------------------------
106
HHSearch
73.94
31%
-58
* C14 *
3CNL
1
RBGA_THEMA
A:
[9-251]
-----------------------------------------------------
E
K
A
K
-
R
Q
I
K
D
L
-
L
R
L
V
N
T
V
V
E
V
R
D
A
R
A
P
F
A
T
S
A
Y
G
V
D
------
F
-----
S
R
--
K
E
T
I
I
L
L
N
K
V
D
I
A
D
E
K
T
----
T
----
K
K
W
V
E
F
F
K
K
--
Q
---
G
--------
K
R
V
I
T
T
H
K
G
E
P
R
K
V
-
L
L
K
K
L
S
---------------
F
D
R
L
A
R
V
L
I
V
G
V
P
N
T
G
K
S
T
I
I
N
K
L
K
G
K
-----
R
------
A
----------------------
K
G
I
Q
----
W
F
S
----
L
E
N
-
G
V
K
I
L
D
T
P
G
I
L
Y
K
N
I
F
S
E
D
L
A
A
K
----
L
L
L
V
G
S
L
P
V
E
R
I
E
D
Q
R
-----------
I
-----
F
---
E
R
------------
A
F
E
--------
I
F
A
R
S
I
-
G
I
---
E
S
S
F
S
E
F
F
E
D
F
A
R
K
R
G
L
LKKGG
V
P
---------
D
I
---------
E
R
A
L
M
L
F
F
T
E
V
A
Q
G
K
A
G
R
V
S
F
E
R
---
P
E
------
D
I
---------------------------------------------------------------
109
HHSearch
58.63
21%
-73
- C14 -
2YV5
1
RSGA_AQUAE
A:
[73-230]
------------------------------------------------------------
I
R
P
K
-
V
A
N
V
D
R
V
I
I
V
E
T
L
K
M
P
E
F
N
N
Y
-
L
L
D
-
N
M
L
V
V
Y
E
Y
---
F
K
--
V
E
P
V
I
V
F
N
K
I
D
L
L
N
E
E
E
K
K
E
-
L
----
E
R
W
I
S
I
Y
R
D
--
A
---
G
---
Y
---
D
V
L
K
V
S
A
K
T
G
E
G
I
D
E
-
L
V
D
Y
L
E
------------------
G
F
I
C
I
L
A
G
P
S
G
V
G
K
S
S
I
L
S
R
L
T
G
E
-----
E
------
L
----
R
T
Q
E
V--------
T
T
---
T
G
V
R
----
L
I
P
----
F
G
K
-
G
S
F
V
G
D
T
P
G
F
S
K
V
E
A
T
M
F
V
K
P
R
E
----
V
R
N
Y
F
R
E
F
L
R
Y
Q
C
K
Y
P
-----------
D
-----
C
---
T
H
------------
T
N
E
P
G
C
A
V
K
E
A
V
K
N
G
E
I
-
S
C
E
R
Y
K
S
Y
L
K
I
I
K
V
Y
L
E
E
I
K
E
L
-----
C
R
---------
E
D
------------------------------------------------------------------------------------------------------------
112
HHSearch
57.25
26%
-69
- C14 -
2RCN
2
RSGA_SALTY
A:
[125-281]
-------------------------------------------------------------
K
P
I
-
A
A
N
I
D
Q
I
V
-
I
V
S
A
I
L
P
E
L
S
L
N
I
-
I
D
-
R
Y
---
L
V
G
C
E
T
L
Q
--
V
E
P
L
I
V
L
N
K
I
D
L
L
D
D
E
G
----
M
D
F
V
-
N
E
Q
M
D
I
Y
R
N
--
I
---
G
---
Y
---
R
V
L
M
V
S
S
H
T
Q
D
G
L
K
P
-
L
E
E
A
L
------------------
T
G
R
I
S
I
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
L
L
G
L
-----
Q
------
N
EILT
N
---------------------TA
A
R
L
Y
H
----
F
P
H
-
G
G
D
V
I
D
S
P
G
V
R
E
F
G
L
W
H
L
E
P
E
Q
I
----
T
Q
G
F
V
E
F
H
D
Y
L
G
H
C
K
Y
-----------
R
-----
D
---
C
K
------------
H
D
A
D
P
G
C
A
I
R
E
A
V
E
N
G
A
-
I
A
E
T
R
F
E
N
Y
H
R
I
L
E
S
M
A
-----------------------------------------------------------------------------------------------------------------------------------
108
HHSearch
54.86
26%
-56
- C14 -
3H2Y
1
?
A:
[66-225]
---------------------------------------------------------------
I
-
G
K
S
D
A
L
V
V
K
I
V
D
I
F
D
F
N
G
S
W
L
P
G
L
H
-
R
F
---
V
-----
G
N
--
N
K
V
L
L
V
G
N
K
A
D
L
I
P
K
S
V
K
H
D
K
V
----
K
H
W
M
R
Y
S
A
K
Q
-
L
---
G
---
L
K
P
E
D
V
F
L
I
S
A
A
K
G
Q
G
I
A
E
-
L
A
D
A
I
E
Y
Y
R
--------------
G
G
K
D
V
Y
V
V
G
C
T
N
V
G
K
S
T
F
I
N
R
M
I
K
E
-----
F
S
DETE
N
V
----
I
-----
T
T
S
H
F
P
-------
D
L
I
----
D
I
P
----
L
D
E
-
E
S
S
L
Y
D
T
P
G
I
I
N
H
H
Q
M
A
H
Y
V
G
K
Q
----
S
L
K
L
I
T
P
T
K
E
I
K
P
M
V
F
-----------
Q
-----
L
---
N
E
------------
E
Q
T
L
F
F
S
G
L
A
R
F
D
Y
V
S
G
-
G
R
R
A
F
T
C
H
F
S
N
R
L
T
I
H
R
T
K
L
E
K
-----
A
D
---------
E
L
---------
Y
K
N
H
A
G
D
L
L
S
P
P
T
P
E
E
L
E
N
M
P
E
L
---
V
K
------
Y
E
F
N
I
R
-----------------------------------------------------------
110
HHSearch
54.23
22%
-69
- C14 -
1U0L
1
RSGA_THEMA
A:
[78-235]
------------------------------------------------------------
T
K
P
H
-
V
A
N
V
D
Q
V
I
L
V
V
T
V
K
M
P
E
T
S
T
Y
-
I
I
D
-
K
F
---
L
V
L
A
E
K
N
E
--
L
E
T
V
M
V
I
N
K
M
D
L
Y
D
E
D
D
----
L
----
R
K
V
R
E
L
E
E
I
YS
G
---
L
---
Y
---
P
I
V
K
T
S
A
K
T
G
M
G
I
E
E
-
L
K
E
Y
L
K
G
------------------
K
I
S
T
M
A
G
L
S
G
V
G
K
S
S
L
L
N
A
I
N
P
G
-----
L
------
K
----
L
-----
R
------
T
T
---
T
T
A
Q
----
L
L
K
----
F
D
F
-
G
G
Y
V
V
D
T
P
G
F
A
N
L
E
I
N
D
I
E
P
E
E
L
----
K
H
Y
F
K
E
F
G
D
K
Q
C
F
F
S
D
-----------
C
-----
N
---
H
V
------------
D
E
P
E
C
G
V
K
E
A
V
E
N
G
E
I
A
-
E
S
R
Y
E
N
Y
V
K
M
F
Y
E
L
L
G
R
R
----------------------------------------------------------------------------------------------------------------------------------
107
HHSearch
50.06
23%
-45
- C14 -
3EC1
1
?
A:
[61-226]
-------------------------------------------------------
F
L
-
S
M
L
H
R
I
-
G
E
S
K
A
L
V
V
N
I
V
D
I
F
D
F
N
G
S
F
I
P
G
L
P
-
R
F
---
A
-----
A
D
--
N
P
I
L
L
V
G
N
K
A
D
L
L
P
R
S
V
K
Y
P
K
L
----
L
R
W
M
R
R
M
A
E
E
-
L
---
G
LCP
V
---
D
V
C
L
V
S
A
A
K
G
I
G
M
A
K
-
V
M
E
A
I
N
R
Y
R
--------------
E
G
G
D
V
Y
V
V
G
C
T
N
V
G
K
S
T
F
I
N
R
I
I
E
E
A
T
G
K
G
N
------
V
----
I
-----
T
T
S
Y
F
P
G
T
T
---
L
D
M
I
----
E
I
P
----
L
E
S
-
G
A
T
L
Y
D
T
P
G
I
I
N
H
H
Q
M
A
H
F
V
D
A
R
----
D
L
K
I
I
T
P
K
R
E
I
H
P
R
V
Y
-----------
Q
-----
L
---
N
E
------------
G
Q
T
L
F
F
G
G
L
A
R
L
D
Y
I
K
G
-
G
R
R
S
F
V
C
Y
M
A
N
E
L
T
V
H
R
T
K
L
E
K
-----
A
D
---------
S
L
---------
Y
A
N
Q
L
G
E
L
L
S
P
P
S
K
R
Y
A
A
E
F
P
P
L
---
V
P
------
R
S
L
S
V
K
-----------------------------------------------------------
129
Fugue
48.30
18%
-9
- C9 -
3EC1
1
?
A:
[59-369]
-----------------------------------------------------
D
D
F
L
-
S
M
L
H
R
I
-
G
E
S
K
A
L
V
V
N
I
V
D
I
F
D
F
N
G
S
F
I
P
G
L
P
-
R
F
---
A
-----
A
D
--
N
P
I
L
L
V
G
N
K
A
D
L
L
P
R
S
V
----
K
----
Y
P
K
L
L
R
W
M
R
--
R
---
M
---
A
---
E
E
L
G
L
C
P
V
D
V
C
L
V
S
A
-
A
K
G
I
G
M
A
K
V
M
E
A
I
N
R
Y
R
E
G
G
------
D
V
Y
V
V
G
C
T
N
V
G
K
S
T
F
I
N
R
I
I
E
E
-----
A
------
T
----
G
K
G
N
V
I
T
T
S
Y
F
P
G
T
T
---
L
D
M
I
----
E
I
P
----
L
E
S
-
G
A
T
L
Y
D
T
P
G
I
I
N
H
H
Q
M
A
H
F
V
D
A
R
----
D
L
K
I
I
T
P
K
R
E
I
H
P
R
V
Y
-----------
Q
L
N
EG
Q
T
---
L
F
FGGL
A
R
L
D
YIKG
G
R
R
S
F
V
C
Y
M
A
N
E
L
T
V
H
R
-
T
K
L
E
K
A
D
S
L
Y
A
N
Q
L
G
E
L
L
S
P
P
S
-----
K
R
---------
Y
A
---------
A
E
F
P
P
L
V
P
R
S
L
S
V
K
E
-
R
K
T
D
I
V
F
---
S
G
L
G
W
V
T
C
N
D
P
G
A
Q
L
V
V
H
A
P
KG
V
D
V
F
I
R
QSLI-----------------------------------------
111
HHSearch
47.08
20%
-63
- C14 -
1T9H
6
RSGA_BACSU
A:
[81-238]
-------------------------------------------------------------
R
P
P
-
I
C
N
V
D
Q
A
V
L
V
F
S
A
V
Q
P
S
F
S
T
-
A
L
L
D
-
R
F
---
L
V
L
V
E
A
N
D
--
I
Q
P
I
I
C
I
T
K
M
D
L
I
E
D
Q
D
----
T
E
D
T
I
Q
A
Y
A
E
D
Y
R
N
--
I
---
G
---
Y
---
D
V
Y
L
T
S
S
K
D
Q
D
S
L
A
D
-
I
I
P
H
F
------------------
Q
D
K
T
T
V
F
A
G
Q
S
G
V
G
K
S
S
L
L
N
A
I
S
P
--------------------------------
T
---
R
H
V
E
----
L
I
H
----
T
-
S
-
G
G
L
V
A
D
T
P
G
F
S
S
L
E
F
T
D
I
E
E
E
E
L
----
G
Y
T
F
P
D
I
R
E
K
S
S
S
C
K
F
-----------
R
-----
G
---
C
L
------------
H
L
K
E
P
K
C
A
V
K
Q
A
V
E
D
G
E
-
L
K
Q
Y
R
Y
D
H
Y
V
E
F
M
T
E
I
K
D
R
K
P
R
-----
Y
------------------------------------------------------------------------------------------------------------------------
130
Fugue
46.52
13%
-49
- C6 -
1MKY
6
DER_THEMA
A:
[2-439]
A
T
V
L
I
V
G
R
P
NVG
K
S
T
L
F
N
K
L
V
KDPV
Q
D
T
V
E
W
YG
K
T
F
K
L
V
D
T
C
G
V
F
D
N
P
Q
D
I
--
I
S
Q
K
M
K
E
V
T
L
N
M
I
R
E
A
D
L
V
L
F
V
V
D
G
K
R
G
I
T
K
E
D
E
S
L
A
-
D
F
---
L
-----
R
K
S
T
V
D
T
I
L
V
A
N
K
A
E
N
L
R
E
F
E
----
R
----
E
V
K
P
E
L
Y
S
L
--
G
---
F
---
G
---
E
P
I
P
V
S
A
E
H
N
I
N
L
D
T
M
L
E
T
I
I
K
K
L
E
E
K
G
-
L
D
L
E
S
K
P
E
I
T
D
A
I
K
V
A
I
V
G
R
P
N
V
G
K
S
T
L
F
N
A
I
L
N
K
-----
E
------
R
----
A
-----
L
V
S
P
I
P
V
D
D
---
E
V
F
I
-----------
D
G
R
-
K
Y
V
F
V
D
T
A
G
L
E
K
Y
S
N
Y
R
V
V
D
S
I
E
K
AD
V
V
V
I
V
L
D
A
T
Q
G
I
T
R
Q
D
Q
R
M
A
G
L
M
E
R
R
G
R
A
-----
S
---
V
V
------------
V
F
N
K
W
D
L
V
V
H
R
E
K
R
Y
D
E
-
F
T
K
L
F
R
E
K
L
Y
F
I
D
Y
S
P
L
I
F
T
S
A
-----
D
K
---------
G
W
N
I
D
R
M
I
D
A
M
N
L
A
Y
A
S
Y
T
T
K
V
P
S
S
A
I
N
S
A
L
Q
K
V
---
L
A
------
F
T
N
L
P
R
GLKIF
F
G
V
Q
VDIKPP
T
F
L
F
F
V
NSIEKVK
N
P
Q
K
I
F
L
R
K
L
I
R
D
YVFPFEG
S
P
I
F
L
K
F
K
R
S
R
118
HHSearch
46.02
38%
-40
* C12 *
3IEV
2
ERA_AQUAE
A:
[9-72]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
-----
K
------
V
----
S
-----
I
I
S
P
K
A
G
T
T
---
R
M
R
V
----
L
G
V
K
N
I
P
N
E
A
-
Q
I
I
F
L
D
T
P
G
I
Y
E
P
K
K
S
D
V
L
G
H
S
M
----
V
E
I
A
K
Q
S
L
E
E
A
D
V
I
L
F
-----------
M
-----
I
---
D
A
------------
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
I
K
-
P
L
N
K
P
V
I
V
V
I
N
K
I
D
K
I
G
P
A
K
N
V
-----
L
P
---------
L
I
---------
D
E
I
H
K
K
H
P
E
L
T
E
I
V
P
I
S
A
L
K
G
A
N
---
L
D
------
E
L
V
K
T
I
-----------------------------------------------------------
127
HHSearch
44.36
12%
-75
- C14 -
3IEV
1
ERA_AQUAE
A:
[84-182]
----------------------------------------------------------
E
I
A
K
Q
S
-
L
E
E
A
D
V
I
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
---
I
KP---
L
N
--
K
P
V
I
V
V
I
N
K
I
D
K
I
G
P
A
K
N---
V
----
L
P
L
I
D
E
I
H
K
--
K
HPE
L
---
T
---
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
-
L
V
K
T
I
L
K
Y
L
P
E
G
E
P
L
F
P
E
D
M
I
T
D
L
P
L
R
L
L
A
A
E
I
V
R
E
K
A
M
M
L
T
R
E
E
V
P
T
-----
S
------
I
----
A
-----
V
K
I
N
E
I
K
P
G
---
D
A
N
P
----
N
M
L
----
V
I
K
-
G
E
I
I
V
D
R
E
N
L
K
P
I
I
I
G
K
K
G
Q
R
L
K
----
E
I
G
K
R
A
R
Q
E
L
E
L
I
L
G
R
-----------
P
-----
V
---
Y
L
------------
E
L
W
V
K
V
V
P
D
W
R
R
R
P
E
Y
V
-
R
L
F
G
Y
A
L
---------------------------------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
44.33
35%
-25
- C12 -
3A1V
1
?
B:
[6-61]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
V
A
L
A
G
C
P
N
V
G
K
T
S
L
F
N
A
L
T
G
T
-----
K
-----------
Q
-----
Y
V
A
N
W
P
G
V
T
VEK
K
E
-
V
----
F
T
Y
----
K
G
Y
-
T
I
N
L
I
D
L
P
G
T
Y
S
L
G
Y
S
S
I
D
E
K
I
A
----
R
D
Y
L
L
K
G
D
A
D
L
V
I
L
V
A
-----------
D
-----
S
---
V
N
------------
P
E
Q
S
L
Y
L
L
L
E
I
L
E
M
E
K
K
-
V
I
L
A
M
T
K
K
T
G
M
K
I
D
R
Y
E
L
Q
K
H
L
-----
G
I
---------
P
V
---------
V
F
T
S
S
V
T
G
E
G
L
E
E
L
K
E
K
I
V
E
Y
A
Q
---
K
N
------
T
I
L
H
R
M
-----------------------------------------------------------
132
Fugue
41.89
15%
-27
- C5 -
1B74
1
MURI_AQUPY
A:
[1-252]
-----------------------------------------
M
K
I
G
I
F
D
S
G
V
GG
L
T
V
L
-
K
A
I
R
N
R
-
Y
R
K
V
D
I
V
Y
L
G
D
T
A
R
V
P
---------------------------------------------------------
Y
G
I
--
R
---
S
---
K
---
D
T
I
I
R
Y
S
L
E
C
A
G
F
L
K
-
D
K
G
V
D
I
I
V
V
A
C
N
T
A
S
A
Y
A
L
E
R
L
K
K
E
I
N
V
P
V
F
G
V
I
E
P
G
V
K
E
A
L
K
K
S
R
N
K
-----
K
------
I
----
G
-----
V
I
G
T
P
A
T
V
K
---
S
G
A
Y
----
Q
R
K
----
L
E
E
G
G
A
D
V
F
A
K
A
C
P
L
F
A
P
L
A
E
E
G
L
L
E
G
----
E
I
T
R
K
V
V
E
H
Y
L
K
E
F
K
G
KID--------
T
-----
L
---
I
L
------------
G
C
T
H
Y
-
P
L
L
K
K
E
I
K
K
F
L
-
G
D
A
E
V
V
D
S
S
E
A
L
S
L
S
L
H
N
F
I
K
D
-----
D
G
---------
S
S
---------
S
L
E
L
F
F
T
D
L
S
P
N
L
Q
F
L
I
K
L
I
L
G
R
D
Y
P
V
K
------
L
A
E
G
V
F
-----------------------------------------------------------
84
PsiBlast_CBE
41.62
35%
-12
- C12 -
3A1S
3
?
B:
[6-61]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
V
A
L
A
G
C
P
N
V
G
K
T
S
L
F
N
A
L
T
G
T
-----
K
-----------
Q
-----
Y
V
A
N
W
P
G
V
T
V
E
K
K
E
G
V
----
F
T
Y
----
K
G
Y
-
T
I
N
L
I
D
L
P
G
T
Y
S
L
G
Y
S
S
I
D
E
K
I
A
----
R
D
Y
L
L
K
G
D
A
D
L
V
I
L
V
A
-----------
D
-----
S
---
V
N
------------
P
E
Q
S
L
Y
L
L
L
E
I
L
E
M
E
K
K
-
V
I
L
A
M
T
A
I
D
E
A
K
K
T
G
M
K
I
D
R
Y
E
-----
L
Q
---------
K
H
---------
L
G
I
P
V
V
F
T
S
S
V
T
G
E
G
L
E
E
L
K
E
K
I
---
V
E
------
Y
A
Q
K
N
T
-----------------------------------------------------------