@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1078: (2015-12-05 )
MKRLLLLEDGSVFEGEAFGADVETSGEIVFSTGMTGYQESITDQSYNGQIITFTYPLIGNYGINRDDYESIRPTCKGVVIYEWAEYPSNWRQQMTLDEFLKLKGIPGISGIDTRALTKIIRKHGTMKACLINEGNSIHEALENLQKSVLLNDQIEQVSTKLAYASPGVGKNIVLVDFGLKHSILRELSQRQCHITVVPHTTTAQEILNLNPDGVLLSNGPGNPEQLPNALQMIQEIQGKIPIFGICMGHQLFAKANGAKTYKMTFGHRGFNHAVRHLQTGQVDFTSQNHGYAVSREDFPEALFITHEEINDKTVEGVRHKYYPAFSVQFHPDAAPGPHDTSYLFDEFINMIDDFQQKS
Atome Classification :
(20 SA)
-.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130....-....140.......150-........160...-----------....170----........--.180.--.--.......190.......200........210.......220----...--...-.---..230..-.-.--.-..240.......250.-......------------------------260....---------...-270------.-....-------------------------------.---------.---------.------280....-----...290.-------......300.......310.......320.......330.......340.......350......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
K
R
L
L
L
LEDGSVFEGEAFGADVETS
G
E
I
V
F
STGMTGY
Q
E
SITDQSYN
G
Q
I
I
T
F
T
YPLIGNYGINR
D
D
Y
E
S
IRPTCK
G
V
V
I
Y
E
WAEYP
S
N
W
R
QQM
T
L
D
E
F
L
K
LKGIPGISGI
D
T
R
A
L
T
K
I
I
R
KHG
T
M
K
A
C
L
I-NEG
N
-
S
I
H
E
A
L
E
N
L
Q
K
S
V
L
L
N
--
D
Q
I
E
Q
V
S
T
K
LAYAS-----------PGVG
K
------
N
I
V
L
V
DFG--
L
K
--
H
--
S
--
I
L
R
E
L
S
QRQ
C
H
I
T
V
VPHTT-
T
A
Q
E
I
LNLNPD
G
V
L
LSNGP------G
N
P
--
E
Q
L
-
P
---
N
A
L
Q
M
I
Q
-
E
-
I
--Q-GKI
P
I
F
G
I
CMG
H
Q
L
F
A-KANG
A
K
------------------------
T
Y
K
M
T
FG---------HR
G
-
F
N
-------
H
-
A
V
R
H
-------------------------------L---------Q---------T------G
Q
V
D
F
TS-----QNH
G
Y
AV-------
S
R
EDFP
E
A
L
F
I
T
HEEIND
K
T
V
E
G
V
R
HKYY
P
A
F
S
V
Q
FHPDAAPGPH
D
T
S
Y
L
F
D
E
F
I
N
M
I
D
D
F
QQKS
1
PsiBlast_PDB
88.38
43%
-77
- C2 -
1JDB
2
CARA_ECOLI
C:
[6-380]
----
L
L
V
L
E
D
G
T
Q
F
H
G
R
A
I
G
A
T
G
S
A
V
G
E
V
V
F
N
T
S
M
T
G
Y
Q
E
I
L
T
D
P
S
Y
S
R
Q
I
V
T
L
T
Y
P
H
I
G
N
V
G
T
N
D
A
D
E
E
S
S
Q
V
H
A
Q
G
L
V
I
R
D
L
P
L
I
A
S
N
F
R
N
T
E
D
L
S
S
Y
L
K
R
H
N
I
V
A
I
A
D
I
D
T
R
K
L
T
R
L
L
R
E
K
G
A
Q
N
G
C
I
I
-
A
G
D
N
P
D
A
A
L
A
L
E
K
A
R
A
F
P
G
L
N
GM
D
L
A
K
E
V
T
T
A
E
A
Y
S
W
TQGSWTLTGGL
P
Q
A
K
K
EDELPF
H
V
V
A
Y
D
F
G
--
A
K
--
R
--
N
--
I
L
R
M
L
V
D
R
G
C
R
L
T
I
V
P
A
Q
T
-
S
A
E
D
V
L
K
M
N
P
D
G
I
F
L
S
N
G
P
------
G
D
P
--
A
P
C
-
D
---
Y
A
I
T
A
I
Q
-
K
F
L
--
E
-
T
D
I
P
V
F
G
I
C
L
G
H
Q
L
L
A
-
L
A
S
G
A
K
------------------------
T
V
K
M
K
F
G
---------
H
H
G
-
G
N
-------
H
-
P
V
K
D
-------------------------------
V
---------
E
---------
K
------
N
V
V
M
I
T
A
-----
Q
N
H
G
F
A
V
-------
D
E
A
T
L
P
A
N
L
R
V
T
H
K
S
L
F
D
G
T
L
Q
G
I
H
R
T
D
K
P
A
F
S
F
Q
G
H
P
E
A
S
P
G
P
H
D
A
A
P
L
F
D
H
F
I
E
L
I
E
Q
Y
R
K
T
-
6
PsiBlast_PDB
88.07
43%
-77
- C2 -
1C30
2
CARA_ECOLI
B:
[6-380]
----
L
L
V
L
E
D
G
T
Q
F
H
G
R
A
I
G
A
T
G
S
A
V
G
E
V
V
F
N
T
S
M
T
G
Y
Q
E
I
L
T
D
P
S
Y
S
R
Q
I
V
T
L
T
Y
P
H
I
G
N
V
G
T
N
D
A
D
E
E
S
S
Q
V
H
A
Q
G
L
V
I
R
D
L
P
L
I
A
S
N
F
R
N
T
E
D
L
S
S
Y
L
K
R
H
N
I
V
A
I
A
D
I
D
T
R
K
L
T
R
L
L
R
E
K
G
A
Q
N
G
C
I
I
-
A
G
D
N
P
D
A
A
L
A
L
E
K
A
R
A
F
P
G
L
N
GM
D
L
A
K
E
V
T
T
A
E
A
Y
S
W
T
Q
G
S
W
T
LTGGL
P
E
A
K
K
EDELP
F
H
V
V
A
Y
D
F
G
--
A
K
--
R
--
N
--
I
L
R
M
L
V
D
R
G
C
R
L
T
I
V
P
A
Q
T
-
S
A
E
D
V
L
K
M
N
P
D
G
I
F
L
S
N
G
P
------
G
D
P
--
A
P
C
-
D
---
Y
A
I
T
A
I
Q
-
K
F
L
--
E
-
T
D
I
P
V
F
G
I
S
L
G
H
Q
L
L
A
-
L
A
S
G
A
K
------------------------
T
V
K
M
K
F
G
---------
H
H
G
-
G
N
-------
H
-
P
V
K
D
-------------------------------
V
---------
E
---------
K
------
N
V
V
M
I
T
A
-----
Q
N
H
G
F
A
V
-------
D
E
A
T
L
P
A
N
L
R
V
T
H
K
S
L
F
D
G
T
L
Q
G
I
H
R
T
D
K
P
A
F
S
F
Q
G
H
P
E
A
S
P
G
P
H
D
A
A
P
L
F
D
H
F
I
E
L
I
E
Q
Y
R
K
T
-
7
PsiBlast_PDB
87.81
43%
-76
- C2 -
1C3O
2
CARA_ECOLI
B:
[6-380]
----
L
L
V
L
E
D
G
T
Q
F
H
G
R
A
I
G
A
T
G
S
A
V
G
E
V
V
F
N
T
S
M
T
G
Y
Q
E
I
L
T
D
P
S
Y
S
R
Q
I
V
T
L
T
Y
P
H
I
G
N
V
G
T
N
D
A
D
E
E
S
S
Q
V
H
A
Q
G
L
V
I
R
D
L
P
L
I
A
S
N
F
R
N
T
E
D
L
S
S
Y
L
K
R
H
N
I
V
A
I
A
D
I
D
T
R
K
L
T
R
L
L
R
E
K
G
A
Q
N
G
C
I
I
-
A
G
D
N
P
D
A
A
L
A
L
E
K
A
R
A
F
P
G
L
N
GM
D
L
A
K
E
V
T
T
A
E
A
Y
S
W
T
Q
G
S
W
T
LTGGL
P
E
A
K
K
EDELP
F
H
V
V
A
Y
D
F
G
--
A
K
--
R
--
N
--
I
L
R
M
L
V
D
R
G
C
R
L
T
I
V
P
A
Q
T
-
S
A
E
D
V
L
K
M
N
P
D
G
I
F
L
S
N
G
P
------
G
D
P
--
A
P
C
-
D
---
Y
A
I
T
A
I
Q
-
K
F
L
--
E
-
T
D
I
P
V
F
G
I
S
L
G
H
Q
L
L
A
-
L
A
S
G
A
K
------------------------
T
V
K
M
K
F
G
---------
H
H
G
-
G
N
-------
H
-
P
V
K
D
-------------------------------
V
---------
E
---------
K
------
N
V
V
M
I
T
A
-----
Q
N
H
G
F
A
V
-------
D
E
A
T
L
P
A
N
L
R
V
T
H
K
S
L
F
D
G
T
L
Q
G
I
H
R
T
D
K
P
A
F
S
F
Q
G
H
P
E
A
S
P
G
P
H
D
A
A
P
L
F
D
H
F
I
E
L
I
E
Q
Y
R
K
T
-
3
PsiBlast_PDB
87.53
43%
-76
- C2 -
1CE8
1
CARA_ECOLI
B:
[6-380]
----
L
L
V
L
E
D
G
T
Q
F
H
G
R
A
I
G
A
T
G
S
A
V
G
E
V
V
F
N
T
S
M
T
G
Y
Q
E
I
L
T
D
P
S
Y
S
R
Q
I
V
T
L
T
Y
P
H
I
G
N
V
G
T
N
D
A
D
E
E
S
S
Q
V
H
A
Q
G
L
V
I
R
D
L
P
L
I
A
S
N
F
R
N
T
E
D
L
S
S
Y
L
K
R
H
N
I
V
A
I
A
D
I
D
T
R
K
L
T
R
L
L
R
E
K
G
A
Q
N
G
C
I
I
-
A
G
D
N
P
D
A
A
L
A
L
E
K
A
R
A
F
P
G
L
N
GM
D
L
A
K
E
V
T
T
A
E
A
Y
S
W
T
Q
G
S
W
T
LTGGL
P
Q
A
K
K
EDELP
F
H
V
V
A
Y
D
F
G
--
A
K
--
R
--
N
--
I
L
R
M
L
V
D
R
G
C
R
L
T
I
V
P
A
Q
T
-
S
A
E
D
V
L
K
M
N
P
D
G
I
F
L
S
N
G
P
------
G
D
P
--
A
P
C
-
D
---
Y
A
I
T
A
I
Q
-
K
F
L
--
E
-
T
D
I
P
V
F
G
I
C
L
G
H
Q
L
L
A
-
L
A
S
G
A
K
------------------------
T
V
K
M
K
F
G
---------
H
H
G
-
G
N
-------
H
-
P
V
K
D
-------------------------------
V
---------
E
---------
K
------
N
V
V
M
I
T
A
-----
Q
N
H
G
F
A
V
-------
D
E
A
T
L
P
A
N
L
R
V
T
H
K
S
L
F
D
G
T
L
Q
G
I
H
R
T
D
K
P
A
F
S
F
Q
G
H
P
E
A
S
P
G
P
H
D
A
A
P
L
F
D
H
F
I
E
L
I
E
Q
Y
R
K
T
-
2
PsiBlast_PDB
87.35
43%
-78
- C2 -
1BXR
2
CARA_ECOLI
B:
[6-380]
----
L
L
V
L
E
D
G
T
Q
F
H
G
R
A
I
G
A
T
G
S
A
V
G
E
V
V
F
N
T
S
M
T
G
Y
Q
E
I
L
T
D
P
S
Y
S
R
Q
I
V
T
L
T
Y
P
H
I
G
N
V
G
T
N
D
A
D
E
E
S
S
Q
V
H
A
Q
G
L
V
I
R
D
L
P
L
I
A
S
N
F
R
N
T
E
D
L
S
S
Y
L
K
R
H
N
I
V
A
I
A
D
I
D
T
R
K
L
T
R
L
L
R
E
K
G
A
Q
N
G
C
I
I
-
A
G
D
N
P
D
A
A
L
A
L
E
K
A
R
A
F
P
G
L
N
GM
D
L
A
K
E
V
T
T
A
E
A
Y
S
W
T
Q
G
S
W
T
LTGGL
P
Q
A
K
K
EDELP
F
H
V
V
A
Y
D
F
G
--
A
K
--
R
--
N
--
I
L
R
M
L
V
D
R
G
C
R
L
T
I
V
P
A
Q
T
-
S
A
E
D
V
L
K
M
N
P
D
G
I
F
L
S
N
G
P
------
G
D
P
--
A
P
C
-
D
---
Y
A
I
T
A
I
Q
-
K
F
L
--
E
-
T
D
I
P
V
F
G
I
C
L
G
H
Q
L
L
A
-
L
A
S
G
A
K
------------------------
T
V
K
M
K
F
G
---------
H
H
G
-
G
N
-------
H
-
P
V
K
D
-------------------------------
V
---------
E
---------
K
------
N
V
V
M
I
T
A
-----
Q
N
H
G
F
A
V
-------
D
E
A
T
L
P
A
N
L
R
V
T
H
K
S
L
F
D
G
T
L
Q
G
I
H
R
T
D
K
P
A
F
S
F
Q
G
H
P
E
A
S
P
G
P
H
D
A
A
P
L
F
D
H
F
I
E
L
I
E
Q
Y
R
K
T
-
5
PsiBlast_PDB
87.08
43%
-79
- C2 -
1M6V
2
CARA_ECOLI
B:
[6-380]
----
L
L
V
L
E
D
G
T
Q
F
H
G
R
A
I
G
A
T
G
S
A
V
G
E
V
V
F
N
T
S
M
T
G
Y
Q
E
I
L
T
D
P
S
Y
S
R
Q
I
V
T
L
T
Y
P
H
I
G
N
V
G
T
N
D
A
D
E
E
S
S
Q
V
H
A
Q
G
L
V
I
R
D
L
P
L
I
A
S
N
F
R
N
T
E
D
L
S
S
Y
L
K
R
H
N
I
V
A
I
A
D
I
D
T
R
K
L
T
R
L
L
R
E
K
G
A
Q
N
G
C
I
I
-
A
G
D
N
P
D
A
A
L
A
L
E
K
A
R
A
F
P
G
L
N
GM
D
L
A
K
E
V
T
T
A
E
A
Y
S
W
T
Q
G
S
W
T
LTGGL
P
Q
A
K
K
EDELP
F
H
V
V
A
Y
D
F
G
--
A
K
--
R
--
N
--
I
L
R
M
L
V
D
R
G
C
R
L
T
I
V
P
A
Q
T
-
S
A
E
D
V
L
K
M
N
P
D
G
I
F
L
S
N
G
P
------
G
D
P
--
A
P
C
-
D
---
Y
A
I
T
A
I
Q
-
K
F
L
--
E
-
T
D
I
P
V
F
G
I
C
L
G
H
Q
L
L
A
-
L
A
S
G
A
K
------------------------
T
V
K
M
K
F
G
---------
H
H
G
-
G
N
-------
H
-
P
V
K
D
-------------------------------
V
---------
E
---------
K
------
N
V
V
M
I
T
A
-----
Q
N
H
G
F
A
V
-------
D
E
A
T
L
P
A
N
L
R
V
T
H
K
S
L
F
D
G
T
L
Q
G
I
H
R
T
D
K
P
A
F
S
F
Q
G
H
P
E
A
S
P
----
A
A
P
L
F
D
H
F
I
E
L
I
E
Q
Y
R
K
T
-
4
PsiBlast_PDB
86.95
43%
-78
- C2 -
1T36
1
CARA_ECOLI
B:
[6-380]
----
L
L
V
L
E
D
G
T
Q
F
H
G
R
A
I
G
A
T
G
S
A
V
G
E
V
V
F
N
T
S
M
T
G
Y
Q
E
I
L
T
D
P
S
Y
S
R
Q
I
V
T
L
T
Y
P
H
I
G
N
V
G
T
N
D
A
D
E
E
S
S
Q
V
H
A
Q
G
L
V
I
R
D
L
P
L
I
A
S
N
F
R
N
T
E
D
L
S
S
Y
L
K
R
H
N
I
V
A
I
A
D
I
D
T
R
K
L
T
R
L
L
R
E
K
G
A
Q
N
G
C
I
I
-
A
G
D
N
P
D
A
A
L
A
L
E
K
A
R
A
F
P
G
L
N
GM
D
L
A
K
E
V
T
T
A
E
A
Y
S
W
T
Q
G
S
W
T
LTGGL
P
E
A
K
K
EDELP
F
H
V
V
A
Y
D
F
G
--
A
K
--
R
--
N
--
I
L
R
M
L
V
D
R
G
C
R
L
T
I
V
P
A
Q
T
-
S
A
E
D
V
L
K
M
N
P
D
G
I
F
L
S
N
G
P
------
G
D
P
--
A
P
D
-
D
---
Y
A
I
T
A
I
Q
-
K
F
L
--
E
-
T
D
I
P
V
F
G
I
C
L
G
H
Q
L
L
A
-
L
A
S
G
A
K
------------------------
T
V
K
M
K
F
G
---------
H
H
G
-
G
N
-------
H
-
P
V
K
D
-------------------------------
V
---------
E
---------
K
------
N
V
V
M
I
T
A
-----
Q
N
H
G
F
A
V
-------
D
E
A
T
L
P
A
N
L
R
V
T
H
K
S
L
F
D
G
T
L
Q
G
I
H
R
T
D
K
P
A
F
S
F
Q
G
H
P
E
A
S
P
G
P
H
D
A
A
P
L
F
D
H
F
I
E
L
I
E
Q
Y
R
K
T
-
8
PsiBlast_PDB
86.76
43%
-74
- C2 -
1KEE
2
CARA_ECOLI
B:
[6-380]
----
L
L
V
L
E
D
G
T
Q
F
H
G
R
A
I
G
A
T
G
S
A
V
G
E
V
V
F
N
T
S
M
T
G
Y
Q
E
I
L
T
D
P
S
Y
S
R
Q
I
V
T
L
T
Y
P
H
I
G
N
V
G
T
N
D
A
D
E
E
S
S
Q
V
H
A
Q
G
L
V
I
R
D
L
P
L
I
A
S
N
F
R
N
T
E
D
L
S
S
Y
L
K
R
H
N
I
V
A
I
A
D
I
D
T
R
K
L
T
R
L
L
R
E
K
G
A
Q
N
G
C
I
I
-
A
G
D
N
P
D
A
A
L
A
L
E
K
A
R
A
F
P
G
L
N
GM
D
L
A
K
E
V
T
T
A
E
A
Y
S
W
T
Q
G
S
W
T
LTGGL
P
E
A
K
K
EDELP
F
H
V
V
A
Y
D
F
G
--
A
K
--
R
--
N
--
I
L
R
M
L
V
D
R
G
C
R
L
T
I
V
P
A
Q
T
-
S
A
E
D
V
L
K
M
N
P
D
G
I
F
L
S
N
G
P
------
G
D
P
--
A
P
C
-
D
---
Y
A
I
T
A
I
Q
-
K
F
L
--
E
-
T
D
I
P
V
F
G
I
-
L
G
H
Q
L
L
A
-
L
A
S
G
A
K
------------------------
T
V
K
M
K
F
G
---------
H
H
G
-
G
N
-------
H
-
P
V
K
D
-------------------------------
V
---------
E
---------
K
------
N
V
V
M
I
T
A
-----
Q
N
H
G
F
A
V
-------
D
E
A
T
L
P
A
N
L
R
V
T
H
K
S
L
F
D
G
T
L
Q
G
I
H
R
T
D
K
P
A
F
S
F
Q
G
H
P
E
A
S
P
G
P
H
D
A
A
P
L
F
D
H
F
I
E
L
I
E
Q
Y
R
K
T
-
46
Fugue
50.56
42%
-104
- C2 -
1A9X
-
CARA_ECOLI
B:
[1-149]
I
K
S
A
L
L
V
L
E
D
G
T
Q
F
H
G
R
A
I
G
A
T
G
S
A
V
G
E
V
V
F
N
T
S
M
T
G
Y
Q
E
I
L
T
D
P
S
Y
S
R
Q
I
V
T
L
T
Y
P
H
I
G
N
V
G
T
N
D
A
D
E
E
S
S
Q
V
H
A
Q
G
L
V
I
R
D
L
P
L
I
A
S
N
F
R
N
T
E
D
L
S
S
Y
L
K
R
H
N
I
V
A
I
A
D
I
D
T
R
K
L
T
R
L
L
R
E
K
G
A
Q
N
G
C
I
I
A
G
D
N
P
-
D
A
A
L
A
L
E
K
A
R
A
F
P
G
L
N
--
G
M
D
L
A
K
E
V
T
T
A
E
A
Y
-----------
S
W
T
Q
G
------
S
W
T
L
T
G
G
L
--
P
Q
--
A
--
K
--
K
E
D
E
L
P
F
H
V
V
A
Y
D
F
G
A
K
R
N
-
I
L
R
M
L
V
D
R
G
C
R
L
T
I
V
P
A
Q
T
------
S
A
E
--
D
V
L
-
K
---
M
N
P
D
G
I
F
-
L
-
S
--
N
-
G
P
G
D
P
A
P
C
D
Y
A
I
T
A
I
Q
-
K
F
L
E
T
D
------------------------
I
P
V
F
G
I
C
---------
Y
G
L
-
G
H
-------
Q
-
L
L
A
L
-------------------------------
A
---------
S
---------
G
------
A
K
T
V
K
M
K
-----
F
G
H
H
G
G
N
-------
H
P
V
K
D
V
E
K
N
V
V
M
I
T
A
Q
N
H
G
F
A
V
D
E
A
T
L
P
A
N
L
R
V
T
H
K
S
L
F
D
G
T
L
Q
G
I
H
R
T
D
K
P
A
F
S
F
Q
G
N
P
E
A
S
P
G
59
HHSearch
50.50
25%
-69
* C2 *
2A9V
3
GUAAA_THEAC
A:
[12-205]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
L
------
K
I
Y
V
V
D
N
G
--
G
Q
WT
H
--
R
--
E
W
R
V
L
R
E
L
G
V
D
T
K
I
V
P
N
D
I
-
D
S
S
E
L
--
D
G
L
D
G
L
V
L
S
G
G
A
------
P
N
I
--
D
E
E
L
D
---
K
L
G
S
V
G
K
-
Y
-
I
--
D
D
H
N
Y
P
I
L
G
I
C
V
G
A
Q
F
I
A
-
L
H
F
G
A
S
------------------------
V
V
K
A
K
H
P
---------
E
F
G
-
K
--------
T
-
K
V
S
V
-------------------------------
M
---------
H
SENIFGG--
L
------
P
S
E
I
T
V
W
-----
E
N
H
N
D
E
I
-------
I
--
N
L
P
D
D
F
T
L
A
A
S
S
-
A
T
C
Q
V
Q
G
F
Y
H
K
T
R
P
I
Y
A
T
Q
F
H
P
E
V
E
H
T
Q
-
Y
G
R
D
I
F
R
N
F
I
G
I
C
A
S
Y
R
E
I
Q
15
PsiBlast_PDB
48.11
28%
-133
- C2 -
1GPM
1
GUAA_ECOLI
A:
[9-97]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
L
I
L
D
F
G
--
S
Q
--
Y
--
T
Q
L
V
A
R
R
V
R
E
L
G
V
Y
C
E
L
W
A
W
D
V
-
T
E
A
Q
I
R
D
F
N
P
S
G
I
I
L
S
G
G
P
------
E
S
T
TE
E
N
S
-
P
---
R
A
P
Q
Y
V
----
F
--
E
-
A
G
V
P
V
F
G
V
C
Y
G
M
Q
T
M
A
-
M
Q
L
G
G
H
------------------------
V
E
A
S
N
E
R
---------
E
F
G
-
Y
A
-------
Q
-
V
E
V
V
-------------------------------
N
---------
D
---------
S
------
A
L
V
R
G
I
E
-----
D
A
L
T
A
D
G
-------
K
P
L
L
D
V
W
M
S
H
G
D
K
V
T
A
I
P
S
D
F
I
T
V
A
S
T
E
S
C
P
F
A
I
M
A
N
E
E
K
R
F
Y
G
V
Q
F
H
P
E
V
T
H
T
R
Q
G
M
R
M
L
E
R
F
V
62
HHSearch
47.98
22%
-79
- C2 -
1QDL
-
TRPG_SULSO
B:
[2-195]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
------
L
T
L
I
I
D
N
Y
--
D
S
F
V
Y
--
N
--
I
A
Q
I
V
G
E
L
G
S
Y
P
I
V
I
R
N
D
E
I
S
I
K
G
I
E
R
I
D
P
D
R
L
I
I
S
P
G
P
------
G
T
P
--
E
K
R
-
E
DIG
V
S
L
D
V
I
K
-
Y
----
L
G
K
R
T
P
I
L
G
V
C
L
G
H
Q
A
I
G
-
Y
A
F
G
A
K
------------------------
I
R
R
A
R
K
V
---------
F
H
G
-
K
I
-------
S
-
N
I
I
L
-------------------------------
V
---------
N
NSPLSLYYG
I
------
A
K
E
F
K
A
T
-----
R
Y
H
S
L
V
V
-------
D
E
--
V
H
R
P
L
I
V
D
A
I
S
A
E
D
N
E
I
M
A
I
H
H
E
E
Y
P
I
Y
G
V
Q
F
H
P
E
S
V
G
T
S
-
L
G
Y
K
I
L
Y
N
F
L
N
R
V
-------
17
PsiBlast_PDB
47.98
26%
-82
- C2 -
2A9V
3
GUAAA_THEAC
A:
[16-196]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Y
V
V
D
N
G
GQ
W
T
--
H
--
R
--
E
W
R
V
L
R
E
L
G
V
D
T
K
I
V
P
N
D
I
-
D
S
S
E
L
D
G
L
--
D
G
L
V
L
S
G
G
A
------
P
N
I
--
D
E
E
-
L
---
D
K
L
G
S
V
G
-
K
-
Y
I
D
D
-
H
N
Y
P
I
L
G
I
C
V
G
A
Q
F
I
A
-
L
H
F
G
A
S
------------------------
V
V
K
A
K
H
P
---------
E
F
G
-
K
T
-------
K
V
S
V
M
H
-------------------------------
S
---------
E
---------
N
------
I
F
G
G
L
P
S
E
I
T
V
W
E
N
H
N
D
E
I
-------
I
--
N
L
P
D
D
F
T
L
A
A
S
S
A
T
C
Q
-
V
Q
G
F
Y
H
K
T
R
P
I
Y
A
T
Q
F
H
P
E
V
----
E
H
T
Q
Y
G
R
D
I
F
R
N
F
I
G
I
C
A
S
Y
R
69
HHSearch
46.84
19%
-84
- C2 -
2VXO
-
GUAA_HUMAN
A:
[29-218]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
------
A
V
V
I
L
D
A
G
------
Y
G
K
V
--
I
D
R
R
V
R
E
L
F
V
Q
S
E
I
F
P
L
E
T
-
P
A
F
A
I
K
E
Q
G
F
R
A
I
I
I
S
G
G
P
---------------------
A
P
W
F
D
P
A
-
I
--
F
T
I
G
K
P
V
L
G
I
C
Y
G
M
Q
M
M
N
-
K
V
F
G
G
T
------------------------
V
H
K
-----------------
V
--------
F
-
N
I
S
V
-------------------------------
D
---------
N
TCSLFRG--
L
------
Q
K
E
E
V
V
L
-----
L
T
H
G
D
S
V
-------
D
--
K
V
A
D
G
F
K
V
V
A
R
S
--
G
N
I
V
A
G
I
A
N
E
S
K
K
L
Y
G
A
Q
F
H
P
E
V
G
L
T
E
-
N
G
K
V
I
L
K
N
F
L
Y
D
I
A
G
C
S
G
T
F
65
HHSearch
46.56
23%
-77
- C2 -
2YWB
-
GUAA_THET8
A:
[1-185]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
L
V
L
D
F
G
--
S
Q
--
Y
T
R
L
--
I
A
R
R
L
R
E
L
R
A
F
S
L
I
L
P
G
D
A
-
P
L
E
E
V
L
K
H
R
P
Q
A
L
I
L
S
G
G
P
------
R
S
V
--
F
D
P
-
D
----
A
P
R
P
D
P
-
R
-
L
--
F
S
S
G
L
P
L
L
G
I
C
Y
G
M
Q
L
L
A
-
Q
E
L
G
G
R
------------------------
V
E
R
A
------------
E
Y
G
-
K
A
L
L
T
R
H
E
-
G
-
P
L
F
R
-------------------------------
G
---------
L
----------------
E
G
E
V
Q
V
W
-----
M
S
H
Q
D
A
V
-------
T
--
A
P
P
P
G
W
R
V
V
A
E
T
-
E
E
N
P
V
A
A
I
A
S
P
D
G
R
A
Y
G
V
Q
F
H
P
E
V
A
H
T
P
-
K
G
M
Q
I
L
E
N
F
L
E
L
A
G
V
K
R
D
W
T
9
PsiBlast_PDB
45.75
29%
-80
- C2 -
2D7J
-
GUAAA_PYRHO
A:
[3-170]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
I
M
D
N
G
--
G
Q
Y
V
H
--
R
--
I
W
R
T
L
R
Y
L
G
V
E
T
K
I
I
P
N
T
T
-
P
L
E
E
I
K
A
M
N
P
K
G
I
I
F
S
G
G
P
SLENT-
G
N
C
--
E
K
V
-------
L
E
H
Y
D
-
E
-
F
--
N
---
V
P
I
L
G
I
C
L
G
H
Q
L
I
A
-
K
F
F
G
G
K
------------------------
V
G
R
---
G
---------
E
K
A
E
Y
S
-------
L
-
V
E
I
E
-------------------------------
I
---------
I
---------
D
------
E
D
E
I
F
K
G
-----
L
P
K
R
L
K
V
W
E
S
HMDE
V
K
E
L
P
P
K
F
K
I
L
A
R
S
E
T
C
P
--
I
E
A
M
K
H
E
E
L
P
I
Y
G
V
Q
F
H
P
E
V
A
H
T
E
K
G
E
E
I
L
R
N
F
A
K
L
C
G
E
L
-----
70
HHSearch
45.72
23%
-75
- C2 -
3TQI
-
GUAA_COXBU
A:
[6-204]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Q
H
------
R
I
L
I
L
D
F
G
--
S
Q
--
Y
A
Q
L
--
I
A
R
R
V
R
E
I
G
V
Y
C
E
L
M
P
C
D
I
-
D
E
E
T
I
R
D
F
N
P
H
G
I
I
L
S
G
G
P
------
E
----------------
A
P
A
-
F
-
I
--
F
E
I
G
C
P
V
L
G
I
C
Y
G
M
Q
T
M
A
-
Y
Q
L
G
G
K
------------------------
V
N
--------------
E
F
G
-
H
A
Q
L
R
V
L
NP
A
-
F
L
F
D
G------------------------------
I
---------
E
---------
D
QVSPQG
E
P
L
L
D
V
W
-----
M
S
H
G
D
I
V
-------
S
--
E
L
P
P
G
F
E
A
T
A
C
T
-
D
N
S
P
L
A
A
M
A
D
F
K
R
R
F
F
G
L
Q
F
H
P
E
V
T
H
T
P
-
Q
G
H
R
I
L
A
H
F
V
I
H
I
C
Q
C
I
P
N
W
68
HHSearch
45.56
24%
-60
- C2 -
3UOW
-
?
A:
[7-233]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
------
K
I
L
V
L
N
F
G
--
S
Q
--
Y
F
H
L
--
I
V
K
R
L
N
N
I
K
I
F
S
E
T
K
D
Y
G
V
-
E
L
K
D
I
K
D
M
N
I
K
G
V
I
L
S
G
G
P
------
Y
S
V
--
T
E
A
-
G
SPH
L
K
K
E
V
F
E
-
Y
-
F
--
L
E
K
K
I
P
I
F
G
I
C
Y
G
M
Q
E
I
A
-
V
Q
M
N
G
E
------------------------
V
K
K
S
K
T
S
---------
E
Y
G
-
C
T
---------
D
V
N
I
L
R
NDNINNITYCRNFSS
A
M
D
L
Y
S
N
Y
K
L
M
NCC
L
F--------
E
NI-------
K
------
S
D
I
T
T
V
W
-----
M
N
H
N
D
E
V
-------
T
--
K
I
P
E
N
F
Y
L
V
S
S
S
-
E
N
C
L
I
C
S
I
Y
N
K
E
Y
N
I
Y
G
V
Q
Y
H
P
E
V
Y
E
S
L
-
D
G
E
L
M
F
Y
N
F
A
Y
N
I
C
K
C
K
K
F
D
16
PsiBlast_PDB
45.40
23%
-91
- C2 -
3UOW
-
?
A:
[10-212]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
V
L
N
F
G
--
S
Q
Y
F
H
--
L
--
I
V
K
R
L
N
N
I
K
I
F
S
E
T
K
D
Y
G
V
-
E
L
K
D
I
K
D
M
N
I
K
G
V
I
L
S
G
G
P
YSVTEA
G
S
P
--
H
L
K
-
K
---
E
V
F
E
Y
F
----
L
--
E
-
K
K
I
P
I
F
G
I
C
Y
G
M
Q
E
I
A
V
Q
M
N
G
E
V
K
K
S
K
T
S
E
Y
G
C
T
D
V
N
I
L
R
NDNINNI
T
Y
C
R
N
F
-SS
A
M
D
L
Y
S
N
Y
K
L
-
M
N
----------
C
C
L
-------------------------------
F
---------
E
---------
N
------
I
K
S
D
I
T
T
V
W
---
M
N
H
N
D
E
V
-------
T
K
--
I
P
E
N
F
Y
L
V
S
S
S
E
N
-
C
L
I
C
S
I
Y
N
K
E
Y
N
I
Y
G
V
Q
Y
H
P
E
V
Y
E
S
L
D
G
E
L
M
F
Y
N
F
A
Y
N
I
C
K
C
K
K
F
D
P
67
HHSearch
45.33
20%
-61
- C2 -
1GPM
1
GUAA_ECOLI
A:
[6-205]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
K
H
------
R
I
L
I
L
D
F
G
--
S
Q
--
Y
T
Q
L
--
V
A
R
R
V
R
E
L
G
V
Y
C
E
L
W
A
W
D
V
-
T
E
A
Q
I
R
D
F
N
P
S
G
I
I
L
S
G
G
P
------
E
S
T
--
T
E
E
-
N
----
S
P
R
A
P
Q
-
Y
-
V
--
F
E
A
G
V
P
V
F
G
V
C
Y
G
M
Q
T
M
A
-
M
Q
L
G
G
H
------------------------
V
E
A
S
N
E
R
---------
E
F
G
-
Y
--------
A
-
Q
V
E
V
-------------------------------
V
NDSALVRGI
E
---------
D
ALTADG
K
P
L
L
D
V
W
-----
M
S
H
G
D
K
V
-------
T
--
A
I
P
S
D
F
I
T
V
A
S
T
-
E
S
C
P
F
A
I
M
A
N
E
E
K
R
F
Y
G
V
Q
F
H
P
E
V
T
H
T
R
-
Q
G
M
R
M
L
E
R
F
V
R
D
I
C
Q
C
E
A
L
W