@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1160: (2015-12-05 )
MKFEYIAEERCKVKTLLKSHDVSRGLLAKIKYRGGKIFVNGEEQNAIFLLEIGDVVTIDIPDEPSHETLEPVPHDLDIVYEDDHFLILNKPFGFASIPSSIHSNTIANFIKHYYVSNNYANQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQAKAIEKRYYALVSGSGDLADSGDIIAPIARDVDSIITRRVHESGKYAHTSYQVVARYGDVRLVDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRMDLGINRQALHCHSLSFYDPFMGKINKQTLDLTDDFDSVIMELH
Atome Classification :
(20 SA)
---.........10--.-........20-.........30........40.-.-..-...-.-50........60........70........80......-..90........100-.-.--.-.....110.......120.......130.......-140.......150.......160.......170..-.....180.......190.-.--..-.---...200.......210...--.....220.......230.-......240.......-250------..-------------.-------------.-------------.....260.......270.......280.......290..------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MK
F
E
Y
I
A
E
E
R
---
C
-
K
V
K
T
L
L
K
SH--DVSR
G
L
L
A
K
I
K
YRG
G
K
I
F
VNGE-E-Q
N
-
A
I
F
-
L
-
L
E
IG
D
V
V
T
I
DIPDEPSHETLEPVPHD
L
D
I
V
Y
EDD
H
F
L
I
-
L
NKPFGFASI
P
S
S
I
--
H
-
S
--
N
-
T
I
A
N
F
I
K
H
Y
YVSNNYAN
Q
Q
V
H
I
V
T
R
LDRDTS
G
L
M
L
-
F
AKHGY
A
H
A
R
L
D
K
Q
L
Q
A
K
A
I
E
K
R
Y
Y
A
L
V
SGSGDLA-DSG
D
I
I
A
P
I
A
R
D
V
D
S
I
-
I
T
-
R
--
R
V
-H---ESGKYAH
T
S
Y
Q
V
V
A
R-YG
D
--
V
R
L
V
D
I
K
LHTG
R
T
H
Q
I
R
V
H
-
F
AHIGFPLLGDDLYGG-R--------MD-------------L-------------G-------------INR
Q
A
L
H
CHSLSFY
D
P
F
M
G
KINK
Q
T
LDLTD
D
F
D
S
V
I
M
ELH------------
39
Fugue
98.88
33%
-103
- C5 -
2IST
3
RLUD_ECOLI
A:
[1-324]
A
Q
R
V
Q
L
T
A
T
V
S
E
N
QLG
Q
-
R
L
D
Q
A
L
A
E
M
F
P
D
Y
S
R
S
R
I
K
E
W
-
I
L
D
Q
R
V
L
V
N
G
K
-
V
C
D
K
-
P
K
E
-
K
-
V
L
G
G
E
Q
V
A
I
N
A
E
I
E
R
F
----
E
P
Q
D
I
P
L
D
I
V
Y
E
D
E
D
I
I
I
-
I
N
K
P
R
D
L
V
V
H
P
G
A
G
--
N
P
D
--
G
-
T
V
L
N
A
L
L
H
Y
Y
-
P
P
I
A
D
V
P
R
A
G
I
V
H
R
L
D
K
D
T
T
G
L
M
V
-
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
A
I
G
H
--
M
T
-
A
G
G
T
V
D
E
P
I
S
R
H
P
T
K
R
-
T
H
-
M
--
A
V
-
H
---
P
M
G
K
P
A
V
T
H
Y
R
I
M
E
H
-
F
R
V
--
H
T
R
L
R
L
R
L
E
T
G
R
T
H
Q
I
R
V
H
-
M
A
H
I
T
H
P
L
V
G
D
P
V
Y
G
G
-
R
--------
P
R
P
P
K
GAS
E
A
F
I
S
T
L
R
-------------
K
-------------
F
D
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
Q
D
M
V
E
L
I
E
V
M
R
A
D
F
E
E
H
KDEVDW
19
HHSearch
89.05
33%
-101
- C5 -
1V9F
1
RLUD_ECOLI
A:
[76-312]
----------------------------------------------------------------------------------
F
E
P
Q
D
I
P
L
D
I
V
Y
E
D
E
D
I
I
I
-
I
N
K
P
R
D
L
V
V
H
P
G
A
G
--
N
-
P
D-
G
-
T
V
L
N
A
L
L
H
Y
Y
P
P
-
I
A
D
V
P
R
A
G
I
V
H
R
L
D
K
D
T
T
G
L
M
V
-
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
A
I
G
H
--
M
T
-
A
G
G
T
V
D
E
P
I
S
R
H
P
T
K
R
-
T
H
-
M
--
A
V
-
H
---
P
M
G
K
P
A
V
T
H
Y
R
I
M
E
H
-
F
R
V
--
H
T
R
L
R
L
R
L
E
T
G
R
T
H
Q
I
R
V
H
-
M
A
H
I
T
H
P
L
V
G
D
P
V
Y
G
G
-
R
--------
P
R
-------------
P
PKGAS
E
A
F
I
S
T
L
R
K
-------------
F
D
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
Q
D
M
V
E
L
I
E
V
M
R
------------
2
PsiBlast_PDB
85.40
37%
-93
- C5 -
2IST
2
RLUD_ECOLI
A:
[76-291]
----------------------------------------------------------------------------------
F
E
P
Q
D
I
P
L
D
I
V
Y
E
D
E
D
I
I
I
-
I
N
K
P
R
D
L
V
V
H
P
G
A
G
--
N
-
P
--
D
G
T
V
L
N
A
L
L
H
Y
Y
P
P
I
A
D
V
P
R
-
A
G
I
V
H
R
L
D
K
D
T
T
G
L
M
V
-
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
--
A
I
G
H
M
T
-
A
G
G
T
V
D
E
P
I
S
R
H
P
T
K
R
-
T
H
-
M
--
A
V
-
H
---
P
M
G
K
P
A
V
T
H
Y
R
I
M
E
H
-
F
R
V
--
H
T
R
L
R
L
R
L
E
T
G
R
T
H
Q
I
R
V
H
-
M
A
H
I
T
H
P
L
V
G
D
P
V
Y
G
G
-
R
--------
P
R
-------------
P
-------------
P
K
GAS
E
A
F
I
S
T
L
R
K
F
D
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
Q
D
M
V
E
L
I
E
V
M
R
------------
1
PsiBlast_PDB
85.13
37%
-94
- C5 -
1V9F
1
RLUD_ECOLI
A:
[76-291]
----------------------------------------------------------------------------------
F
E
P
Q
D
I
P
L
D
I
V
Y
E
D
E
D
I
I
I
-
I
N
K
P
R
D
L
V
V
H
P
G
A
G
--
N
-
P
--
D
G
T
V
L
N
A
L
L
H
Y
Y
P
P
I
A
D
V
P
R
-
A
G
I
V
H
R
L
D
K
D
T
T
G
L
M
V
-
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
--
A
I
G
H
M
T
-
A
G
G
T
V
D
E
P
I
S
R
H
P
T
K
R
-
T
H
-
M
--
A
V
-
H
---
P
M
G
K
P
A
V
T
H
Y
R
I
M
E
H
-
F
R
V
--
H
T
R
L
R
L
R
L
E
T
G
R
T
H
Q
I
R
V
H
-
M
A
H
I
T
H
P
L
V
G
D
P
V
Y
G
G
-
R
--------
P
R
-------------
P
-------------
P
KGAS
E
A
F
I
S
T
L
R
K
F
D
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
Q
D
M
V
E
L
I
E
V
M
R
------------
18
PsiBlast_CBE
84.40
34%
-105
- C5 -
1XPI
2
RLUC_ECOLI
B:
[7-227]
-------------------------------------------------------------------------------------------
I
L
Y
E
D
D
H
I
L
V
-
L
N
K
P
S
G
T
A
V
H
G
G
S
G
--
L
-
S
--
F
-
G
V
I
E
G
L
R
A
L
R
P
E
A
R
F
----
L
E
L
V
H
R
L
D
R
D
T
S
G
V
L
L
-
V
A
K
K
R
S
A
L
R
S
L
H
E
Q
L
R
E
K
G
M
Q
K
D
Y
L
A
L
V
R
G
Q
W
Q
-
S
-
H
V
K
S
V
Q
A
P
L
L
K
N
I
L
Q
S
-
G
E
-
R
I
V
R
V
-
S
---
Q
E
G
K
P
S
E
T
R
F
K
V
E
E
R
-
Y
A
F
--
A
T
L
V
R
C
S
P
V
T
G
R
T
H
Q
I
R
V
H
-
T
Q
Y
A
G
H
P
I
A
F
D
D
R
Y
G
D
-
R
E
F
D
R
Q
L
T
E
A
G
-------------
T
-------------
G
-------------
L
N
R
L
F
L
H
A
A
A
L
K
F
T
H
P
G
T
G
E
V
M
R
I
E
A
P
M
D
E
G
L
K
R
C
L
Q
K
L
R
------------
5
PsiBlast_PDB
84.01
34%
-109
- C5 -
1XPI
3
RLUC_ECOLI
A:
[7-227]
-------------------------------------------------------------------------------------------
I
L
Y
E
D
D
H
I
L
V
-
L
N
K
P
S
G
T
A
V
H
G
G
S
G
--
L
-
S
--
F
-
G
V
I
E
G
L
R
A
L
R
--
A
R
F
----
L
E
L
V
H
R
L
D
R
D
T
S
G
V
L
L
-
V
A
K
K
R
S
A
L
R
S
L
H
E
Q
L
R
E
K
G
M
Q
K
D
Y
L
A
L
V
R
G
Q
W
Q
-
S
-
H
V
K
S
V
Q
A
P
L
L
K
N
I
L
Q
S
-
G
E
-
R
I
V
R
V
-
S
---
Q
E
G
K
P
S
E
T
R
F
K
V
E
E
R
-
Y
A
F
--
A
T
L
V
R
C
S
P
V
T
G
R
T
H
Q
I
R
V
H
-
T
Q
Y
A
G
H
P
I
A
F
D
D
R
Y
G
D
-
R
E
F
D
R
Q
L
T
E
A
G
-------------
T
-------------
G
-------------
L
N
R
L
F
L
H
A
A
A
L
K
F
T
H
P
G
T
G
E
V
M
R
I
E
A
P
M
D
E
G
L
K
R
C
L
Q
K
L
R
------------
20
HHSearch
83.77
36%
-98
- C5 -
1V9K
1
RLUC_ECOLI
A:
[3-225]
------------------------------------------------------------------------------------------
V
I
M
Y
E
D
D
H
I
L
V
-
L
N
K
P
S
G
T
A
V
H
G
G
S
G
--
L
-
S
--
F
-
G
V
I
E
G
L
R
A
L
R
P
----
E
A
R
F
L
E
L
V
H
R
L
D
R
D
T
S
G
V
L
L
-
V
A
K
K
R
S
A
L
R
S
L
H
E
Q
L
R
E
K
G
M
Q
K
D
Y
L
A
L
V
R
G
Q
--
W
Q
S
H
V
K
S
V
Q
A
P
L
L
K
N
I
L
Q
S
G
E
R
I
V
--
R
V
-
S
---
Q
E
G
K
P
S
E
T
R
F
K
V
E
E
R
-
Y
A
F
--
A
T
L
V
R
C
S
P
V
T
G
R
T
H
Q
I
R
V
H
-
T
Q
Y
A
G
H
P
I
A
F
D
D
R
Y
G
D
-
R
--------
E
F
D
R
Q
L
T
E
A
G-----
T
-------------
G
-------------
L
N
R
L
F
L
H
A
A
A
L
K
F
T
H
P
G
T
G
E
V
M
R
I
E
A
P
M
D
E
G
L
K
R
C
L
Q
K
M
R
------------
7
PsiBlast_PDB
79.91
33%
-106
- C5 -
2I82
2
RLUA_ECOLI
A:
[12-217]
-----------------------------------------------------------------------------------------
L
V
I
L
Y
Q
D
D
H
I
M
V
-
V
N
K
P
S
G
L
L
S
V
P
G
R
L
EE
H
-
K
--
D
-
S
V
M
T
R
I
Q
R
D
Y
-------
P
Q
A
E
S
V
H
R
L
D
M
A
T
S
G
V
I
V
-
V
A
L
T
K
A
A
E
R
E
L
K
R
Q
F
R
E
R
E
P
K
K
Q
Y
V
A
R
V
W
G
H
P
S
P
A
-
E
-
G
L
V
D
L
P
L
I
C
D
W
P
N
R
-
P
K
-
Q
--
K
V
C
Y
---
E
T
G
K
P
A
Q
T
E
Y
E
V
V
E
Y
-
A
A
D
N
T
A
R
V
V
-
L
K
P
I
T
G
R
S
H
Q
L
R
V
H
-
M
L
A
L
G
H
P
I
L
G
D
R
F
Y
A
S
P
E
--------
A
R
-------------
A
-------------
M
-------------
A
P
R
L
L
L
H
A
E
M
L
T
I
T
H
P
A
Y
G
--
N
S
M
T
F
K
A
P
A
D
F
--------------------
6
PsiBlast_PDB
79.50
36%
-100
- C5 -
1V9K
1
RLUC_ECOLI
A:
[4-208]
-------------------------------------------------------------------------------------------
I
M
Y
E
D
D
H
I
L
V
-
L
N
K
P
S
G
T
A
V
H
G
G
S
G
--
L
-
S
--
F
-
G
V
I
E
G
L
R
A
L
R
P
E
A
R
F
----
L
E
L
V
H
R
L
D
R
D
T
S
G
V
L
L
-
V
A
K
K
R
S
A
L
R
S
L
H
E
Q
L
R
E
K
G
M
Q
K
D
Y
L
A
L
V
R
G
Q
W
Q
-
S
-
H
V
K
S
V
Q
A
P
L
L
K
N
I
L
Q
S
-
G
E
-
R
I
V
R
V
-
S
---
Q
E
G
K
P
S
E
T
R
F
K
V
E
E
R
-
Y
A
F
--
A
T
L
V
R
C
S
P
V
T
G
R
T
H
Q
I
R
V
H
-
T
Q
Y
A
G
H
P
I
A
F
D
D
R
Y
G
D
-
R
E
F
D
R
Q
L
T
E
A
G
-------------
T
-------------
G
-------------
L
N
R
L
F
L
H
A
A
A
L
K
F
T
H
P
G
T
G
E
V
M
R
I
E
A
P
M
D
E
G
L
K
R
C
L
Q
K
M
R
------------
21
HHSearch
76.36
32%
-92
- C5 -
2I82
2
RLUA_ECOLI
A:
[8-216]
-------------------------------------------------------------------------------------
Q
E
P
W
L
V
I
L
Y
Q
D
D
H
I
M
V
-
V
N
K
P
S
G
L
L
S
V
P
G
R
L
--
E
-
E
HK
D
-
S
V
M
T
R
I
Q
R
D
-------
Y
P
Q
A
E
S
V
H
R
L
D
M
A
T
S
G
V
I
V
-
V
A
L
T
K
A
A
E
R
E
L
K
R
Q
F
R
E
R
E
P
K
K
Q
Y
V
A
R
V
W
G
H
--
P
S
P
A
E
G
L
V
D
L
P
L
I
C
D
W
P
N
R
-
P
K
-
Q
--
K
V
C
Y
---
E
T
G
K
P
A
Q
T
E
Y
E
V
V
E
Y
A
A
D
N
--
T
A
R
V
V
L
K
P
I
T
G
R
S
H
Q
L
R
V
H
-
M
L
A
L
G
H
P
I
L
G
D
R
F
Y
A
S
-
P
--------
E
A
R
------------
A
-------------
M
-------------
A
P
R
L
L
L
H
A
E
M
L
T
I
T
H
P
A
Y
G
N
S
M
T
F
K
A
P
A
D
F
----------------------
4
PsiBlast_PDB
61.42
36%
-44
- C5 -
1PRZ
-
RLUD_ECOLI
A:
[77-292]
----------------------------------------------------------------------------------
F
E
P
Q
D
I
P
L
D
I
V
Y
E
D
E
D
I
I
V
-
I
N
K
P
R
D
L
V
V
H
P
G
A
G
--
N
-
P
--
D
G
T
V
L
N
A
L
L
H
Y
Y
P
P
I
A
D
V
-
P
R
A
G
I
V
H
R
L
D
K
D
T
T
G
L
M
V
-
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
--
A
I
G
H
M
T
-
A
G
G
T
V
D
E
P
I
S
R
H
P
T
K
R
-
T
H
-
M
--
A
V
-
H
---
P
M
G
K
P
A
V
T
H
Y
R
I
M
E
H
-
F
R
V
--
H
T
R
L
R
L
R
L
E
T
G
R
T
H
Q
I
R
V
H
-
M
A
H
I
T
H
P
L
V
G
D
P
V
Y
G
G
-
R
--------
P
R
-------------
P
-------------
P
KGAS
E
A
F
I
S
T
L
R
K
F
D
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
Q
D
M
V
E
L
I
E
V
M
R
------------
3
PsiBlast_PDB
60.01
36%
-45
- C5 -
1QYU
-
RLUD_ECOLI
A:
[77-292]
----------------------------------------------------------------------------------
F
E
P
Q
D
I
P
L
D
I
V
Y
E
D
E
D
I
I
I
-
I
N
K
P
R
D
L
V
V
H
P
G
A
G
--
N
-
P
--
D
G
T
V
L
N
A
L
L
H
Y
Y
P
P
I
A
D
V
-
P
R
A
G
I
V
H
R
L
D
K
D
T
T
G
L
M
V
-
V
A
K
T
V
P
A
Q
T
R
L
V
E
S
L
Q
R
R
E
I
T
R
E
Y
E
A
V
--
A
I
G
H
M
T
-
A
G
G
T
V
D
E
P
I
S
R
H
P
T
K
R
-
T
H
-
M
--
A
V
-
H
---
P
M
G
K
P
A
V
T
H
Y
R
I
M
E
H
-
F
R
V
--
H
T
R
L
R
L
R
L
E
T
G
R
T
H
Q
I
R
V
H
-
M
A
H
I
T
H
P
L
V
G
D
P
V
Y
G
G
-
R
--------
P
R
-------------
P
-------------
P
KGAS
E
A
F
I
S
T
L
R
K
F
D
R
Q
A
L
H
A
T
M
L
R
L
Y
H
P
I
S
G
I
E
M
E
W
H
A
P
I
P
Q
D
M
V
E
L
I
E
V
M
R
------------
15
PsiBlast_PDB
59.77
26%
-79
- C5 -
1KSV
1
RSUA_ECOLI
A:
[16-197]
------------------------------
V
S
R
A
I
A
G
R
-
E
I
R
G
N
R
V
T
V
D
G
E
I
V
-
R
N
-
A
A
F
K
L
-
L
P
E
H
D
V
A
Y
D
G
N
P
L
A
Q
Q
H
---------------
G
P
R
Y
F
M
-
L
N
K
P
Q
G
Y
V
C
S
T
D
D
P
--
D
-
H
--
P
-
T
V
L
Y
F
L
------
D
E
P
V
A
W
K
L
H
A
A
G
R
L
D
I
D
T
T
G
L
V
L
-
M
T
D
D
G
Q
W
S
H
R
I
T
S
P
R
H
--
H
C
E
K
T
Y
--
L
V
T
L
E
S
P
V
A
-
D
--
D
T
A
E
Q
F
A
K
G
V
----------
Q
L
-
H
---
N
E
K
D
L
T
K
P
A
V
L
E
V
I
T
-
P
T
Q
--
V
R
L
T
---
I
S
E
G
R
Y
H
Q
V
K
R
M
-
F
A
A
V
G
N
H
V
V
E
L
H
R
E
R
I
-
G
--------
G
I
-------------
T
-------------
L
-------------
D
A
D
L
A
P
G
E
Y
R
P
L
T
E
E
E
I
A
S
V
V
-------------------------------
23
HHSearch
59.60
23%
-73
- C5 -
1KSK
1
RSUA_ECOLI
A:
[2-210]
-----------
S
H
---
M
-
R
L
D
K
F
I
A
Q
Q
L
-
G
V
S
R
A
I
A
G
R
E
I
R
G
N
R
-
V
T
V
D
G
E
-
I
-
V
R
N
A
A
F
-
K
-
L
L
P
E
H
D
V
A
Y
D
G
N
P
------
L
-------
A
-
Q
Q
H
G
P
R
Y
F
M
-
L
N
K
P
Q
G
Y
V
C
S
T
D
D
P
--
D
-
H
--
P
-
T
V
L
Y
F
L
D
E
P
------
V
A
W
K
L
H
A
A
G
R
L
D
I
D
T
T
G
L
V
L
-
M
T
D
D
G
Q
W
S
H
R
I
T
S
P
--
R
H
H
C
E
K
T
Y
L
V
T
L
E
S
P
--
V
A
-
D
-
D
T
A
E
Q
F
A
K
-----
G
-
V
-----
Q
L
-
H
NEK
D
L
T
K
P
A
V
L
E
V
I
-------
T
--
P
T
Q
V
R
L
T
I
S
E
G
R
Y
H
Q
V
K
R
M
-
F
A
A
V
G
N
H
V
V
E
L
H
R
E
R
I
-
G
--------
G
I
-------------
T
-------------
L
-------------
D
A
D
L
A
P
G
E
Y
R
P
L
T
E
E
E
I
A
S
V
V
-------------------------------
41
Fugue
59.32
20%
-89
- C5 -
1KSK
1
RSUA_ECOLI
A:
[1-234]
-----------
G
S
---
H
M
R
L
D
K
F
I
A
Q
Q
--
L
G
V
S
R
A
I
A
G
R
E
I
R
G
N
R
V
T
V
D
G
E
-
I
-
V
R
-
N
A
A
-
F
K
L
L
P
E
H
D
V
A
Y
D
---------------
G
N
P
L
A
Q
Q
H
G
P
R
Y
F
M
L
N
K
P
Q
G
Y
V
C
S
T
D
D
P
--
D
-
H
--
P
-
T
V
L
Y
F
L
D
E
P
V
------
A
W
K
L
H
A
A
G
R
L
D
I
D
T
T
G
L
V
L
M
T
D
D
G
Q
W
S
H
R
I
T
S
P
R
H
H
---
C
E
K
T
Y
L
V
T
L
E
S
-------------
P
V
A
D
D
T
A
E
Q
-
F
A
-
K
--
G
V
-
Q
---
L
H
N
E
K
D
L
T
K
-
P
A
V
L
E
-
V
I
T
--
P
T
Q
V
R
L
T
I
S
E
G
R
Y
H
Q
V
K
-
R
M
F
A
A
V
G
N
H
----------------------------------------------------------------
V
V
E
L
H
R
E
R
I
G
G
I
T
L
D
A
D
L
A
P
G
E
Y
R
P
L
T
E
E
E
I
A
S
V
V
---------------
24
HHSearch
59.30
23%
-69
- C5 -
3DH3
1
RLUF_ECOLI
A:
[4-208]
----------
D
S
S
---
V
-
R
L
N
K
Y
I
S
E
S
G-
I
C
S
R
R
E
A
D
R
Y
I
E
Q
G
N
-
V
F
L
N
G
K
-
R
-
A
T
-
I
G
D
-
Q
-
V
K
P
G
D
V
V
K
V
N
G
Q
L
I
------
E
------
P
R
E
A
E
D
L
V
L
I
A
-
L
N
K
P
V
G
I
V
S
T
T
E
D
G
--
E
-
R
--
D
-
N
I
V
D
F
V
N
H
--------
S
K
R
V
F
P
I
G
R
L
D
K
D
S
Q
G
L
I
F
-
L
T
N
H
G
D
L
V
N
K
I
L
R
A
G
--
N
D
H
E
K
E
Y
L
V
T
V
D
K
P
--
I
T
-
E
E
-
F
I
R
G
-
M
S
----
A
G
--------
V
-
P
---
I
L
--
G
T
V
T
K
K
C
K
V
K
--
K
E
A
--
P
F
V
F
R
I
T
L
V
Q
G
L
N
R
Q
I
R
R
M
-
C
E
H
F
G
Y
E
V
K
K
L
E
R
T
R
I
-
M
--------
N
V
-------------
S
-------------
L
-------------
S
G
I
P
L
G
E
W
R
D
L
T
D
D
E
L
I
D
L
F
K
L
I
E
N
S
S
S
E
V
----------------------
14
PsiBlast_PDB
59.13
26%
-74
- C5 -
1KSL
1
RSUA_ECOLI
A:
[16-197]
------------------------------
V
S
R
A
I
A
G
R
-
E
I
R
G
N
R
V
T
V
D
G
E
I
V
-
R
N
-
A
A
F
K
L
-
L
P
E
H
D
V
A
Y
D
G
N
P
L
A
Q
Q
H
---------------
G
P
R
Y
F
M
-
L
N
K
P
Q
G
Y
V
C
S
T
D
D
P
--
D
-
H
--
P
-
T
V
L
Y
F
L
------
D
E
P
V
A
W
K
L
H
A
A
G
R
L
D
I
D
T
T
G
L
V
L
-
M
T
D
D
G
Q
W
S
H
R
I
T
S
P
R
H
--
H
C
E
K
T
Y
--
L
V
T
L
E
S
P
V
A
-
D
--
D
T
A
E
Q
F
A
K
G
V
----------
Q
L
-
H
---
N
E
K
D
L
T
K
P
A
V
L
E
V
I
T
-
P
T
Q
--
V
R
L
T
---
I
S
E
G
R
Y
H
Q
V
K
R
M
-
F
A
A
V
G
N
H
V
V
E
L
H
R
E
R
I
-
G
--------
G
I
-------------
T
-------------
L
-------------
D
A
D
L
A
P
G
E
Y
R
P
L
T
E
E
E
I
A
S
V
V
-------------------------------
13
PsiBlast_PDB
58.63
26%
-75
- C5 -
1KSK
1
RSUA_ECOLI
A:
[16-197]
------------------------------
V
S
R
A
I
A
G
R
-
E
I
R
G
N
R
V
T
V
D
G
E
I
V
-
R
N
-
A
A
F
K
L
-
L
P
E
H
D
V
A
Y
D
G
N
P
L
A
Q
Q
H
---------------
G
P
R
Y
F
M
-
L
N
K
P
Q
G
Y
V
C
S
T
D
D
P
--
D
-
H
--
P
-
T
V
L
Y
F
L
------
D
E
P
V
A
W
K
L
H
A
A
G
R
L
D
I
D
T
T
G
L
V
L
-
M
T
D
D
G
Q
W
S
H
R
I
T
S
P
R
H
--
H
C
E
K
T
Y
--
L
V
T
L
E
S
P
V
A
-
D
--
D
T
A
E
Q
F
A
K
G
V
----------
Q
L
-
H
---
N
E
K
D
L
T
K
P
A
V
L
E
V
I
T
-
P
T
Q
--
V
R
L
T
---
I
S
E
G
R
Y
H
Q
V
K
R
M
-
F
A
A
V
G
N
H
V
V
E
L
H
R
E
R
I
-
G
--------
G
I
-------------
T
-------------
L
-------------
D
A
D
L
A
P
G
E
Y
R
P
L
T
E
E
E
I
A
S
V
V
-------------------------------
22
HHSearch
56.47
22%
-77
* C5 *
1VIO
4
RSUA_HAEIN
A:
[2-209]
------------
S
---
L
-
R
L
D
K
F
I
A
E
N
V-
G
L
T
R
S
Q
A
T
K
A
I
R
Q
S
A
-
V
K
I
N
G
E
-
I
-
V
K
S
G
S
V
-
Q
-
I
S
Q
E
D
E
I
Y
F
E
D
E
--------------
L
L
T
W
I
E
E
G
Q
Y
F
M
-
L
N
K
P
Q
G
C
V
C
S
N
D
D
-----
Y
--
P
-
T
I
Y
Q
F
F
D
Y
P
L
------
A
G
K
L
H
S
A
G
R
L
D
V
D
T
T
G
L
V
L
-
L
T
D
D
G
Q
W
S
H
R
I
T
S
P
--
K
H
H
C
E
K
T
Y
L
V
T
L
A
D
P
--
V
E
-
E
N
Y
S
--
A
A
C
A
E
----
G
-
I
L
-
L
R-
G
E
-
K
---
E
P
T
K
P
A
--
K
L
E
I
L
D
-------
D
Y
N
V
N
L
T
I
S
E
G
R
Y
H
Q
V
K
R
M
-
F
A
A
L
G
N
K
V
V
G
L
H
R
W
K
I
-
G
--------
D
V
-------------
V
-------------
L
-------------
D
E
S
L
E
E
G
E
Y
R
P
L
T
Q
S
E
I
E
K
L
V
-------------------------------
27
HHSearch
49.94
24%
-84
- C5 -
2GML
-
RLUF_ECOLI
A:
[1-145]
-----------------------------------------------------------------------------------------------
D
L
V
L
I
A
-
L
N
K
P
V
G
I
V
S
T
T
E
D
G
--
E
-
R
--
D
-
N
I
V
D
F
V
N
H
--------
S
K
R
V
F
P
I
G
R
L
D
K
D
S
Q
G
L
I
F
-
L
T
N
H
G
D
L
V
N
K
I
L
R
A
G
--
N
D
H
E
K
E
Y
L
V
T
V
D
K
P
--
I
T
-
E
E
-
F
I
R
G
-
M
S
----
A
G
--------
V
-
P
---
I
L
G
--
T
V
T
K
K
C
K
V
K
K
--
E
A
--
P
F
V
F
R
I
T
L
V
Q
G
L
N
R
Q
I
R
R
M
-
C
E
H
F
G
Y
E
V
K
K
L
E
R
T
R
I
-
M
--------
N
V
-------------
S
-------------
L
-------------
S
G
I
P
L
G
E
W
R
D
L
T
D
D
E
L
I
D
L
F
K
L
I
E
N
S
S
-------------------------