@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1185: (2015-12-06 )
MRKDNLGIILGLSAYVLWGLLSLYWKLLSGIEAYSTFAYRIIFTVLTMLIYMLVSGRKTVYLKDLKGLVNNKKSFWTMFVASILISINWLVYIFAVTHGHATEASLGYYMMPIISILLSVLVLREHLARVVSLAILIAIMGVGILVYQTGHFPLISLTLALSFGFYGLLKKSISLSSDFSMLVESSFIAPFALIYIVFFAKDFLTDYNILQLVLLSLSGIITAVPLLLFAEAIKRAPLNIIGFIQYINPTIQLLLALFIFKETIVSGEVIGFIFIWLAILVFSIGQVHTMLKKGK
Atome Classification :
(18 SA)
------------------------------------------------------.........10........20...--.....30...----------...-----..40........50......-----..60........--------70..--......80........90...--.....100...-....110........120---.........130.......----------140...-..-..150...---....160...-------....170-.-......180......---.190.......200---------------.....--------------..210.......220------....-----.....230-----.......240-.......250.-----------------.....----.260..-.....270.......280------.....-....290...-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------MRKDN
L
G
I
I
L
G
L
S
A
Y
V
L
W
G
L
L
S
L
Y
--
W
K
L
L
S
G
I
E
A
Y
----------
S
T
F
-----
A
Y
R
I
I
F
T
V
L
T
M
L
I
Y
M
L
VSGR-----
K
T
V
Y
L
K
D
L
K
G
L
V--------NN
K
K
--
S
F
W
T
M
F
V
A
S
I
L
I
S
I
N
W
L
V
Y
I
F
--
A
VTHGHATEAS-L
G
Y
Y
M
-
M
P
I
I
S
I
L
L
S
V
-----
L
V
L
R
E
H
L
A
R
V
V
S
L
A
I
L
I
A
I
----------
M
G
V
G
I
L
-
V
Y-QTGH
F
P
L
I
---
S
L
T
L
A
L
S
F
G
F
-------
Y
G
L
L
K
K
S-I-SLS
S
D
F
S
M
L
V
E
SSF
I
---
A
P
F
A
L
I
Y
I
V
F
F
A
K
D
---------------
F
LT
D
Y
--------------
N
I
L
Q
L
V
L
L
S
L
S
G
I
--------
I
T
A
V
-----
P
L
L
L
F
A
E
A
-----
I
K
RAP
L
N
I
I
G
-
F
I
Q
YI
N
P
T
I
Q
L
-----------------
L
L
A
L
F
----
I
F
K
E
T
I-VSG
E
V
I
G
F
I
F
I
W
L
A
I
L
--------
V
F
S
I
G
-
Q
V
H
T
M
L
KKGK-
19
Fugue
93.73
18%
-148
- C2 -
4RGP
6
?
A:
[2-256]
------------------------------------------------------
N
A
T
E
Q
E
T
L
T
I
L
L
D
V
Y
A
-------
Y
--
Y
Q
A
Y
Q
I
V
K
A
S
----------
Q
F
F
-----
S
D
D
I
I
F
-----
L
L
E
L
L
K
E
R
R
-----
E
----
L
N
V
D
F
L
F
--------
Q
N
Q
V
--
H
L
Q
E
L
E
L
T
Y
---
H
I
S
L
L
---------
D
N
A
Y
E
E
E
L
-
L
A
N
Y
I
M
D
--------------
L
E
A
K
L
R
N
D
H
I
I
D
F
V
R
S
V
S
P
----------
I
L
Y
R
L
L
M
R
L
M
Q
S
Q
V
A
D
I
N
---
D
Y
I
Y
D
A
K
N
D
Q
-------
Y
D
T
W
K
F
D
-
K
M
H
D
S
A
N
----------------------
P
F
V
Q
N
---------------
F
V
A
K
G
--------------
R
D
S
K
I
T
S
R
S
L
A
D
F
--------
I
Q
L
T
-----
D
L
---
P
Q
A
-----
I
K
D
N
I
L
L
L
R
D
-
F
E
K
S
V
R
N
P
L
A
H
-----------------
L
I
K
P
F
D
E
E
E
L
H
R
T
T
G
-
F
S
S
Q
T
F
L
E
K
I
I
Q
L
A
V
F
S
G
I
H
Y
D
ND
K
F
Y
F
D
-
K
V
N
E
L
I
K
R
I
Y
Q
22
Fugue
73.56
11%
-154
- C1 -
2I0Z
2
?
A:
[25-444]
MHYD
V
I
V
I
G
GG
P
S
G
L
M
A
A
I
G
A
A
E
E
GAN
V
L
L
L
D
KGNKLG
R
K
L
A
I
SGGGRCNVTNR
L
P
L
D
E
I
V
K
H
I
P
G
N
G
R
F
L
Y
S
A
F
S
I
F
N
N
E
D
I
I
T
F
F
E
N
L
G
V
K
L
K
E
E
D
HG
R
M
F
P
VSNK
A
Q
S
V
V
D
A
L
L
T
R
L
K
D
L
G
V
K
I
R
T
NTPV
E
T
I
E
Y
E
N
G
Q
T
K
A
--------
V
I
L
Q
--
T
G
E
V
L
E
T
N
H
V
V
I
A
V
G
G
K
S
V
P
Q
TG
S
T
G
D
G
Y
A
W
A
E
K
-
A
G
H
T
I
-
T
E
L
F
P
T
E
V
P
I
L
S
NE
P
F
I
R
D
R
S
L
Q
G
L
A
L
R
D
I
N
L
S
V
----------
L
N
A
I
I
S
-
H
K
-
M
D
M
L
F
T
H
F
---
G
L
S
G
P
A
A
L
R
C
-------
S
Q
F
V
V
K
A
-
L
-
K
K
F
K
T
N
T
I
Q
M
S
I
D
A
L
---
P
E
E
N
S
E
Q
L
F
Q
R
M
L
K
---------------
Q
M
K
E
D
PKKG
I
K
N
V
L
KGYVP
E
R
Y
F
L
F
L
L
E
K
N
E
I
DGSEQAGQ
V
S
H
E
-----
K
I
R
A
L
V
K
D
-----
F
K
E
F
T
V
N
V
N
G
-
T
Q
S
I
E
K
A
F
V
T
G
GGVSVKEINPKEMSSKF
T
N
G
L
Y
----
F
C
G
E
V
L
D
I
H
G
Y
T
G
G
Y
N
I
T
S
A
L
V
T
--------
G
R
I
A
G
-
T
T
A
G
E
N
A
K
---
21
Fugue
72.44
15%
-162
- C4 -
3J7W
-
CAPSA_BPT7
A:
[2-344]
---------------------------------------------------ASM
T
G
G
Q
Q
M
G
T
N
Q
G
K
G
V
V
A
A
G
D
K
L
A
L
F
--
L
K
V
F
G
G
-
E
V
L
----------
T
A
F
-----
A
R
T
S
V
T
T
S
R
H
M
V
R
S
--
I
S
S
G
-----
K
S
A
Q
F
P
V
L
G
R
T
Q
A
A
Y
L
A
PGE
N
L
D
D
--
K
R
K
D
I
K
H
T
E
K
V
I
T
I
D
G
L
L
T
A
D
--
V
L
I
Y
D
I
E
D
A
M
N
-
H
Y
D
V
R
-
S
E
Y
T
S
Q
L
G
E
S
-----
L
A
M
A
A
D
G
A
V
L
A
E
I
A
G
L
C
N
V
ESKYNENIEG
L
G
T
A
T
V
-
I
E
-
T
T
Q
N
K
A
A
L
---
T
D
Q
V
A
L
G
K
E
I
-------
I
A
A
L
T
K
A
R
A
-
A
L
T
K
N
Y
V
P
A
A
D
R
V
F
Y
C
D
P
D
S
Y
S
A
I
L
A
A
L
M
P
N
A
ANYAALIDPEKGSIR
N
V
M
G
F
--------------
E
V
V
E
V
P
H
L
T
A
G
G
A
--------
G
T
A
R
EGTTG
Q
K
H
V
F
P
A
N
KGEGN
V
K
V
A
K
D
N
V
I
G
-
L
F
M
H
R
S
A
V
G
T
V
-----------------
K
L
R
D
L
----
A
L
E
R
A
R
-
R
A
N
F
Q
A
D
Q
I
I
A
K
Y
A
M
G
--------
H
G
G
L
R
P
E
A
A
G
A
V
V
F
K
V
-
18
Fugue
64.16
14%
-143
- C4 -
3WO6
6
YIDC2_BACHD
A:
[1-232]
--------------------------------------------------GQDP
I
T
S
E
S
E
G
I
W
N
H
F
F
V
Y
P
M
S
W
L
I
T
T
V
--
A
N
L
L
N
G
S
Y
G
L
----------
S
I
I
-----
I
V
T
I
L
I
R
L
A
L
L
P
L
T
L
K
Q
Q
K
S
-----
M
R
A
M
Q
V
I
R
P
E
M
E
--------
A
I
Q
K
--
K
Y
-------------------------
K
E
K
A
S
K
D
------------------------
P
K
V
Q
Q
E
M
Q
K
E
L
L
G
L
Y
Q
K
----------
H
G
V
N
P
M
-----
A
G
C
L
P
L
F
----
I
Q
L
P
I
L
M
A
F
-------
Y
F
A
I
M
R
T
-
E
-
E
I
R
Y
H
---------------------------------------------
T
F
--------------
L
W
F
D
L
G
Q
P
D
Y
I
L
P
--------
F
V
A
G
-----
I
T
T
Y
F
Q
F
K
-----
M
T
M
S
H
Q
M
Q
M
K
-
V
M
L
Y
V
M
P
V
M
I
I
-----------------
I
A
G
L
S
----
L
P
----------
S
A
L
S
L
Y
W
V
I
G
N
--------
I
F
M
I
I
-
Q
T
Y
--------
8
HHSearch
47.34
17%
-175
- C- -
3B5D
1
EMRE_ECOLI
A:
[31-105]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
P
S
V
G
T
I
I
--------
C
Y
C
A
-----
S
F
W
L
L
A
Q
T
-----
L
A
Y
I
P
T
G
I
A
Y
A
I
W
S
G
V
G
I
V
L
I
S
-----------------
L
L
S
W
G
----
F
F
G
Q
R
L
-
D
L
P
A
I
I
G
M
M
L
I
C
A
G
V
L
--------
I
I
N
L
L
-
S
----------
6
PsiBlast_PDB
40.84
28%
-75
- C3 -
3RBZ
-
MTHK_METTH
A:
[24-89]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
----------
L
V
L
A
V
I
-
I
Y
-
G
T
A
G
F
H
F
I
EGE
S
W
T
V
S
L
Y
W
T
F
V
T
I
A
TVG
Y
G
D
Y
S
P
S
-
T
-
P
L
G
M
Y
F
T
V
T
L
I
V
L
G
I
---
A
T
F
A
V
A
V
R
H
V
V
I
C
G
---------------
W
S
E
S
T
--------------
L
E
C
L
R
E
L
R
G
S
E
V
F
--------
V
L
A
E
-----
D
E
N
V
R
K
K
V
-----
L
R
S
G
A
N
F
V
H
G
-
D
P
T
R
V
S
D
L
E
K
A
-----------------
N
V
R
G
A
----
R
A
V
I
V
D
-
L
E
S
D
S
E
T
I
H
C
I
L
G
I
R
K
--------
I
D
E
S
V
-
R
I
I
A
E
A
E
R
Y
E
-
10
HHSearch
37.64
13%
-254
- C- -
3B5D
1
EMRE_ECOLI
A:
[30-105]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
P
S
V
G
T
I
I
C
Y
C
A
S
F
W
L
L
A
Q
--
T
L
A
Y
I
P
T
G
I
A
Y
A
I
W
S
G
V
-
G
I
V
L
I
S
L
L
S
W
-----
G
F
F
G
Q
R
L
D
L
P
A
I
I
G
M
M
L
I
C
----------
A
G
V
L
I
I
-
N
L
-
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
32.50
41%
-41
- C3 -
4HUM
1
?
A:
[253-293]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
F
L
---
E
A
S
A
F
S
F
I
V
F
L
I
A
P
---------------
F
G
E
D
Y
--------------
V
A
A
Q
Q
V
G
I
S
L
S
G
I
--------
L
Y
M
I
-----
P
Q
S
V
G
S
A
G
-----
T
V
R
I
G
F
S
L
G
R
-
R
E
F
S
R
A
R
Y
I
S
G
-----------------
V
S
L
V
S
----
G
W
V
L
A
V
-
I
T
V
L
S
L
V
L
F
R
S
P
L
A
S
M
--------
Y
N
D
D
P
-
A
V
L
S
I
A
S
T
V
L
-
5
PsiBlast_PDB
32.15
34%
49
- C3 -
1K1D
-
HYDA_GEOSE
A:
[350-388]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
S
E
G
-----
V
K
K
G
R
I
T
L
N
Q
-
F
V
D
I
V
S
T
R
I
A
K
-----------------
L
F
G
L
F
----
P
K
K
G
T
I
-
V
V
G
S
D
A
D
L
V
I
F
D
P
N
I
E
--------
R
V
I
S
A
-
E
T
H
H
M
A
V
D
Y
N
-
1
PsiBlast_PDB
30.69
41%
-34
- C3 -
4HUK
1
?
A:
[253-293]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
F
L
---
E
A
S
A
F
S
F
I
V
F
L
I
A
P
---------------
F
G
E
D
Y
--------------
V
A
A
Q
Q
V
G
I
S
L
S
G
I
--------
L
Y
M
I
-----
P
Q
S
V
G
S
A
G
-----
T
V
R
I
G
F
S
L
G
R
-
R
E
F
S
R
A
R
Y
I
S
G
-----------------
V
S
L
V
S
----
G
W
V
L
A
V
-
I
T
V
L
S
L
V
L
F
R
S
P
L
A
S
M
--------
Y
N
D
D
P
-
A
V
L
S
I
A
S
T
V
L
-
4
PsiBlast_PDB
30.44
41%
-43
- C3 -
4HUN
1
?
A:
[253-293]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
F
L
---
E
A
S
A
F
S
F
I
V
F
L
I
A
P
---------------
F
G
E
D
Y
--------------
V
A
A
Q
Q
V
G
I
S
L
S
G
I
--------
L
Y
M
I
-----
P
Q
S
V
G
S
A
G
-----
T
V
R
I
G
F
S
L
G
R
-
R
E
F
S
R
A
R
Y
I
S
G
-----------------
V
S
L
V
S
----
G
W
V
L
A
V
-
I
T
V
L
S
L
V
L
F
R
S
P
L
A
S
M
--------
Y
N
D
D
P
-
A
V
L
S
I
A
S
T
V
L
-
2
PsiBlast_PDB
29.61
41%
-45
- C3 -
4HUL
1
?
A:
[253-293]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
F
L
---
E
A
S
A
F
S
F
I
V
F
L
I
A
P
---------------
F
G
E
D
Y
--------------
V
A
A
Q
Q
V
G
I
S
L
S
G
I
--------
L
Y
M
I
-----
P
Q
S
V
G
S
A
G
-----
T
V
R
I
G
F
S
L
G
R
-
R
E
F
S
R
A
R
Y
I
S
G
-----------------
V
S
L
V
S
----
G
W
V
L
A
V
-
I
T
V
L
S
L
V
L
F
R
S
P
L
A
S
M
--------
Y
N
D
D
P
-
A
V
L
S
I
A
S
T
V
L
-
16
Fugue
29.35
27%
119
* C3 *
3H00
-
A:
[1-39]
------------------------------------------------------------------------------------------------------------------
N
N
Y
T
S
L
I
H
S
L
I
E
E
S
-----
Q
N
Q
Q
E
K
N
E
Q
E
L
L
--------
E
L
D
K
W
A
S
L
W
N
W
F
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
26.93
18%
268
- C3 -
2JP3
-
FXYD4_RAT
A:
[24-40]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
G
L
L
C
I
A
G
I
A
--------
L
A
L
S
G
-
K
C
K
C
R
R
N
H
T
P
-
25
Fugue
26.65
35%
-11
* C4 *
3A0B
-
YCF12_THEVL
Y:
[1-28]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
Q
L
T
M
I
A
M
I
G
I
--------
A
G
-------
P
M
I
I
F
L
L
A
-----
V
R
R
G
N
L
G
T
T
G
-
E
R
P
F
S
D
I
I
T
S
V
-----------------
R
Y
W
V
I
----
H
S
I
T
I
P
-
A
L
F
I
A
G
W
L
F
V
S
T
G
L
A
Y
--------
D
V
F
G
T
-
P
R
P
D
S
Y
Y
A
Q
E
-
12
HHSearch
25.77
25%
240
- C3 -
3WU2
-
PSBT_THEVL
T:
[16-29]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
L
-----------------
F
F
F
A
I
----
F
F
R
E
P
P
-
R
I
T
A
N
L
W
E
R
F
C
N
W
V
T
S
--------
T
D
N
R
L
-
Y
V
G
W
F
G
V
I
M
I
-
15
HHSearch
25.70
12%
238
- C3 -
2ZXE
-
?
G:
[26-42]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
A
V
L
C
V
I
G
I
I
--------
I
L
L
A
G
-
K
----------
13
HHSearch
12.60
36%
449
- C3 -
2HAC
-
CD3Z_HUMAN
A:
[14-27]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
L
T
A
-----
L
F
L
R
V
K
F
S
R
S
A
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------