@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1206: (2015-12-06 )
MSKGLKSLYTLLGLISLTLLGFVAVISKQHIYLPSFNWLDWDFNLPSPIDVGMYHYFFWGALVLFVIVLLAILVVLFYPRRYTEYKLADKTGKLMLKKSAIEGFVKTEVLKTGLMKSLSVTAHLYKKKVKVDVKGLLTSRTNVPEQLEHIQSDVELGLKEFFGLEKKMNTRVFVKQVEEENVGNAKTNKSRVE
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10...-------.....20........30--..-.......40........50-......--..60..--------------...-------.---..70.---.......80........90.---.......100----.......110----------......-.120------------------------....-------.---..130.....-..140.........150.-------------......160-.-------......170........180.......190.--------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MS
K
G
L
K
S
L
Y
T
L
L
G
L
-------
I
S
L
T
L
L
G
F
V
A
V
I
SKQ
H
---
I
Y-LPSFNWLDWDFNLPSP
I
D
V
-
G
M
Y
H
Y
F
--
F
W
G
A
L
V
--------------
L
F
V
-------
I
---
V
L
L
A
I
---
L
V
V
L
FYPRRY
T
E
Y
K
LADKTG---
K
L
M
L
K
K
S
A
I
E
----
G
F
V
K
T
E
V
L
K
T
----------
G
L
M
K
S
L
-
S
V
T
A
------------------------
H
L
Y
K
-------
K
---
K
V
K
V
D
V
K
G
LL-TSR--TN
V
P
E
Q
L
E
H
I
Q
S
D
-------------
V
E
L
G
L
K
E
F
F-G-------
L
E
K
KMN
T
R
-
V
F
V
K
Q
V
E
EENVGNAKTNKSRVE--------------------------------------------------------------------------------------------------------------------------------
49
Fugue
79.33
22%
-127
- C1 -
4QCC
-
DGOA_ECOLI
A:
[5-274]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
P
L
I
A
I
L
R
G
I
-------
T
P
D
E
A
L
A
H
V
G
A
V
I
D
A
G
FD
A
V
E
-
I
P
-
L
N
S
P
Q
W
E
Q
S
I
P
A
I
V
D
A
Y
G
D
K
A
L
I
--
G
A
G
T
V
L
K
P
E
Q
V
D
A
L
A
R
M
GCQ
L
I
V
T
PNIH
S
E
V
---
I
R
R
A
V
G
Y
G
M
T
V
C
P
G
C
A
T
A
T
E
A
F
T
A
L
E
A
G
AQ-
A
L
K
I
F
P
S
S
A
F
----
G
P
Q
Y
I
K
A
L
K
A
----------
V
L
P
S
D
I
-
A
V
F
A
V
G
GVTPEN
L
A
Q
W
I
D
A
GCA
G
A
G
L
G
S
D
L
Y
R
AGQS
V
--
E
---
R
T
A
Q
Q
A
A
A
F
V
-
K
A
Y
--
R
E
A
Q
K
Q
K
E
Q
R
Q
D
Q
K
S
A
Y
A
L
G
A
S
L
G
R
Y
M
E
N
S
L
K
E
Q
E
-
K
-------
L
G
I
K
L
D
K
D
-
Q
L
I
A
G
V
Q
D
A
F
A
D
K
S
K
L
S
D
Q
E
I
E
Q
T
L
Q
A
F
E
A------------------------------------------------------------------------------------------------------------------------
21
HHSearch
60.24
16%
-43
- C2 -
3J1Z
-
?
P:
[216-293]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
R
----
Q
R
I
K
L
I
A
K
E
D
----------
P
R
V
L
G
L
H
D
L
R
T
------------------------
R
Q
A
G
-------
K
---
T
V
F
I
Q
F
H
L
E
L
-
D
G
N
--
L
S
L
N
E
A
H
-
S
I
T
D
T
-------------
T
G
L
R
V
K
A
A
F
-
E
-------
D
---
A
E
V
I
-
I
H
Q
D
P
V
Q
V
E
P
T
T
Q
-----------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
60.01
27%
-167
- C2 -
4Y28
-
?
A:
[341-422]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
H
K
G
L
Y
E
I
L
T
T
S
W
H
A
Q
L
S
I
N
L
A
M
L
G
S
L
T
I
V
V
A
Q
H
---
M
Y
S
M
P
P
Y
P
Y
L
A
T
D
Y
--
A
T
Q
L
S
L
-
F
T
H
H
M
W
--
I
G
G
------------------
F
L
-------
I
---
V
G
A
A
A
---
H
A
A
I
F
M
V
R
D
Y
D
P
T
T
R
Y
N
D
L
L
---
D
R
V
L
R
H
R
D
A
I
----
I
S
H
L
N
W
V
C
I
F
----------
L
G
F
H
S
F
-
G
L
Y
I
------------------------
H
N
D
T
-------
M
---
S
A
L
G
R
P
Q
D
M
F
-
S
D
T
--
A
I
Q
L
Q
P
V
F
A
Q
W
I
Q
-------------
N
T
H
A
L
A
P
G
T
-
T
-------
A
P
G
A
T
A
S
T
-
S
L
T
W
G
G
G
D
L
V
A
V
G
N
K
V
A
L
L
P
I
P
--------------------------------------------------------------------------------------------------------------------------------
44
Fugue
59.63
13%
-83
- C1 -
1AVP
1
PRO_ADE02
A:
[1-204]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
S
S
E
Q
E
L
K
A
I
V
K
D
-------
L
G
C
G
P
Y
-
F
L
G
T
Y
D
K
R
F
---
P
G
-
F
V
S
P
H
K
L
A
C
A
I
V
N
T
A
G
R
E
T
-
G
G
V
H
--------
W
M
--------------
A
F
A
-------
W
---
N
P
R
S
K
---
T
C
Y
L
F
E
P
F
G
F
S
D
Q
R
L
K
Q
V
Y
Q
FEY
E
S
L
L
R
R
S
A
I
A
S
SPD
R
C
I
T
L
E
K
S
T
Q
SVQGPNSAA
C
G
L
F
C
C
M
-
F
L
H
A
------------------------
F
A
N
W
-------
P
---
Q
T
P
M
D
H
N
P
T
M
-
N
L
I
--
T
G
V
P
N
S
M
L
N
S
P
Q
V
-------------
Q
P
T
L
R
R
N
Q
E
-
Q
-------
L
Y
S
F
L
E
R
H
S
P
Y
F
R
S
H
S
A
Q
I
R
S
A
T
S
F
C
H
L
K
N
M
--------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
59.62
27%
-165
- C2 -
4XK8
-
?
A:
[341-422]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
H
K
G
L
Y
E
I
L
T
T
S
W
H
A
Q
L
S
I
N
L
A
M
L
G
S
L
T
I
V
V
A
Q
H
---
M
Y
S
M
P
P
Y
P
Y
L
A
T
D
Y
--
A
T
Q
L
S
L
-
F
T
H
H
M
W
--
I
G
G
------------------
F
L
-------
I
---
V
G
A
A
A
---
H
A
A
I
F
M
V
R
D
Y
D
P
T
T
R
Y
N
D
L
L
---
D
R
V
L
R
H
R
D
A
I
----
I
S
H
L
N
W
V
C
I
F
----------
L
G
F
H
S
F
-
G
L
Y
I
------------------------
H
N
D
T
-------
M
---
S
A
L
G
R
P
Q
D
M
F
-
S
D
T
--
A
I
Q
L
Q
P
V
F
A
Q
W
I
Q
-------------
N
T
H
A
L
A
P
G
T
-
T
-------
A
P
G
A
T
A
S
T
-
S
L
T
W
G
G
G
D
L
V
A
V
G
G
K
V
A
L
L
P
I
P
--------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
58.40
27%
-178
- C2 -
4L6V
-
PSAA_SYNY3
A:
[335-416]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
H
K
G
L
Y
E
I
L
T
T
S
W
H
A
Q
L
A
I
N
L
A
L
L
G
S
L
T
I
I
V
A
Q
H
---
M
Y
A
M
P
P
Y
P
Y
Q
A
I
D
Y
--
A
T
Q
L
S
L
-
F
T
H
H
M
W
--
I
G
G
F
L
I
--------------
V
G
A
-------
G
---
A
H
G
A
I
---
F
M
V
R
D
Y
D
P
A
K
N
V
N
N
L
L
D
R
M
L
---
R
H
R
D
A
I
I
S
H
L
----
N
W
V
C
I
F
L
G
F
H
----------
S
F
G
L
Y
I
-
H
N
D
T
------------------------
M
R
A
L
-------
G
---
R
P
Q
D
M
F
S
D
T
A
-
I
Q
L
--
Q
P
I
F
A
Q
W
V
Q
H
L
H
T
-------------
L
A
P
G
A
T
A
P
N
-
A
-------
L
A
T
A
S
Y
A
F
-
G
G
E
T
I
A
V
A
G
K
V
A
M
M
P
I
T
L
G
T
A
D
--------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
58.14
30%
10
- C2 -
3GB8
-
XPO1_HUMAN
A:
[984-1048]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
F
P
------------------------
H
L
Q
D
-------
A
---
Q
V
K
L
F
V
T
G
L
F
-
S
L
N
--
Q
D
I
P
A
F
K
E
H
L
R
-
D
-------------
F
L
V
Q
I
K
E
F
A
-
G
ED
T
S
D
L
F
L
E
E
R
---
E
-
I
A
L
R
Q
A
D
E
E
K
H
K
R
Q
M
S
V
P
G
I
F
N
--------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
57.98
12%
-62
- C2 -
3UEB
-
?
A:
[29-98]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
Q
E
T
I
I
----
D
Y
V
F
D
H
L
T
R
-----------
S
E
V
K
D
I
-
E
V
T
M
------------------------
R
I
N
R
-------
E
ETL
D
L
E
I
E
V
Y
L
E
V
-
P
I
F
VK
V
D
V
D
K
L
I
D
E
A
V
E
R
-------------
A
Y
E
I
V
E
R
K
L
-
R
-------
E
I
A
N
E
----------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
57.76
27%
-164
- C2 -
4RKU
4
PSAA_PEA
A:
[304-385]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
H
K
G
L
Y
E
I
L
T
T
S
W
H
A
Q
L
S
I
N
L
A
M
L
G
S
L
T
I
V
V
A
Q
H
---
M
Y
S
M
P
P
Y
P
Y
L
A
T
D
Y
--
A
T
Q
L
S
L
-
F
T
H
H
M
W
--
I
G
G
------------------
F
L
-------
I
---
V
G
A
A
A
---
H
A
A
I
F
M
V
R
D
Y
D
P
T
T
R
Y
N
D
L
L
---
D
R
V
L
R
H
R
D
A
I
----
I
S
H
L
N
W
V
C
I
F
----------
L
G
F
H
S
F
-
G
L
Y
I
------------------------
H
N
D
T
-------
M
---
S
A
L
G
R
P
Q
D
M
F
-
S
D
T
--
A
I
Q
L
Q
P
V
F
A
Q
W
I
Q
-------------
N
T
H
A
L
A
P
G
T
-
T
-------
A
P
G
A
T
A
S
T
-
S
L
T
W
G
G
G
D
L
V
A
V
G
N
K
V
A
L
L
P
I
P
--------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
57.59
5%
-45
- C2 -
2ZZT
2
?
A:
[12-87]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
----
D
D
I
F
A
V
L
E
R
F
----------
P
N
V
H
N
P
H
R
V
R
I
------------------------
R
R
V
G
-------
T
----
Y
F
I
E
M
D
I
E
V
-
D
G
K
--
M
S
V
K
-
D
A
H
E
L
T
V
K
-------------
I
R
K
E
M
L
K
R
R
D
D
-------
I
---
E
D
V
T
-
I
H
V
E
P
L
G
N
----------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
57.52
13%
-30
- C2 -
3BYP
1
?
A:
[14-87]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
R
A
F
L
Q
E
R
I
R--------
G
R
A
L
E
V
H
D
L
K
T
------------------------
R
R
A
G
-------
P
---
R
S
F
L
E
F
H
L
V
V
-
R
G
D
--
T
P
V
E
E
A
H
-
R
L
C
D
E
-------------
L
E
R
A
L
A
Q
A
F
-
P
-------
G
--
L
-
Q
A
T
-
I
H
V
E
P
E
G
-----------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
57.36
7%
-21
- C2 -
2XCZ
1
?
A:
[16-105]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
S
L
L
----
Q
E
L
S
S
K
L
A
E
L
----------
L
G
K
P
E
K
-
Y
V
M
T
------------------------
S
L
Q
C
G
V
P
M
T
F
S
G
NT-
E
P
T
C
Y
V
E
V
K
S
-
I
G
A
--
L
D
-
G
S
R
T
Q
E
V
S
E
L
-------------
V
C
G
H
I
E
Q
N
L
-
G
-------
I
-
P
A
D
R
I
Y
-
I
G
F
E
D
V
P
A
R
L
W
G
W
N
G
S
T
F
G
-----------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
57.31
5%
-40
- C2 -
3H90
4
FIEF_ECOLI
A:
[208-281]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
----
Q
E
I
I
D
I
V
T
S
W
----------
P
G
V
S
G
A
H
D
L
R
T
------------------------
R
Q
S
G
-------
P
---
T
R
F
I
Q
I
H
L
E
M
-
E
D
S
--
L
P
L
V
Q
A
-
H
M
V
A
D
Q
-------------
V
E
Q
A
I
L
R
R
F
-
P
-------
G
---
S
D
V
I
-
I
H
Q
D
P
C
S
V
V
---------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
57.19
5%
-29
- C2 -
2OS5
2
?
A:
[16-105]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
N
F
E
----
E
R
L
T
D
L
L
A
E
S
----------
M
N
K
P
R
N
-
R
I
A
I
------------------------
E
V
L
A
G
Q
R
I
T
H
G
A
SR-
N
P
V
A
V
I
K
V
E
S
-
I
G
A
--
L
S
-
A
D
D
N
I
R
H
T
Q
K
-------------
I
T
Q
F
C
Q
D
T
L
-
K
-------
L
-
P
K
D
K
V
I
-
I
T
Y
F
D
L
Q
P
I
H
V
G
F
N
G
T
T
V
A
A
A
T
--------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
56.96
27%
-167
- C2 -
3LW5
-
PSAA_PEA
A:
[321-402]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
H
K
G
L
Y
E
I
L
T
T
S
W
H
A
Q
L
S
I
N
L
A
M
L
G
S
L
T
I
V
V
A
Q
H
---
M
Y
S
M
P
P
Y
P
Y
L
A
T
D
Y
--
A
T
Q
L
S
L
-
F
T
H
H
M
W
--
I
G
G
------------------
F
L
-------
I
---
V
G
A
A
A
---
H
A
A
I
F
M
V
R
D
Y
D
P
T
T
R
Y
N
D
L
L
---
D
R
V
L
R
H
R
D
A
I
----
I
S
H
L
N
W
V
C
I
F
----------
L
G
F
H
S
F
-
G
L
Y
I
------------------------
H
N
D
T
-------
M
---
S
A
L
G
R
P
Q
D
M
F
-
S
D
T
--
A
I
Q
L
Q
P
V
F
A
Q
W
I
Q
-------------
N
T
H
A
L
A
P
G
T
-
T
-------
A
P
G
A
T
A
S
T
-
S
L
T
W
G
G
G
D
L
V
A
V
G
N
K
V
A
L
L
P
I
P
--------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
56.59
27%
-171
- C2 -
4KT0
6
PSAA_SYNY3
A:
[335-416]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
H
K
G
L
Y
E
I
L
T
T
S
W
H
A
Q
L
A
I
N
L
A
L
L
G
S
L
T
I
I
V
A
Q
H
---
M
Y
A
M
P
P
Y
P
Y
Q
A
I
D
Y
--
A
T
Q
L
S
L
-
F
T
H
H
M
W
--
I
G
G
F
L
I
--------------
V
G
A
-------
G
---
A
H
G
A
I
---
F
M
V
R
D
Y
D
P
A
K
N
V
N
N
L
L
D
R
M
L
---
R
H
R
D
A
I
I
S
H
L
----
N
W
V
C
I
F
L
G
F
H
----------
S
F
G
L
Y
I
-
H
N
D
T
------------------------
M
R
A
L
-------
G
---
R
P
Q
D
M
F
S
D
T
A
-
I
Q
L
--
Q
P
I
F
A
Q
W
V
Q
H
L
H
T
-------------
L
A
P
G
A
T
A
P
N
-
A
-------
L
A
T
A
S
Y
A
F
-
G
G
E
T
I
A
V
A
G
K
V
A
M
M
P
I
T
L
G
T
A
D
--------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
56.42
9%
-38
- C2 -
3W61
2
?
A:
[9-82]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
I
V
E
A
A
E
R
V
----------
P
G
V
R
G
V
I
H
L
R
A
------------------------
R
Y
V
G
-------
Q
---
D
I
W
A
D
M
I
I
G
V
-
D
P
E
--
N
T
V
E
Q
-
A
H
E
I
C
E
A
-------------
V
Q
A
A
V
C
G
K
I
-
R
-------
R
--
I
E
S
L
A
-
V
S
A
E
A
R
E
-----------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
56.42
27%
-171
- C2 -
2WSE
-
PSAA_PEA
A:
[341-422]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
H
K
G
L
Y
E
I
L
T
T
SWHAQLS
I
N
L
A
M
L
G
S
L
T
I
V
V
A
Q
H
---
M
Y
S
M
P
P
Y
P
Y
L
A
T
D
Y
--
A
T
Q
L
S
L
-
F
T
H
H
M
W
--
I
G
G
------------------
F
L
-------
I
---
V
G
A
A
A
---
H
A
A
I
F
M
V
R
D
Y
D
P
T
T
R
Y
N
D
L
L
---
D
R
V
L
R
H
R
D
A
I
----
I
S
H
L
N
W
V
C
I
F
----------
L
G
F
H
S
F
-
G
L
Y
I
------------------------
H
N
D
T
-------
M
---
S
A
L
G
R
P
Q
D
M
F
-
S
D
T
--
A
I
Q
L
Q
P
V
F
A
Q
W
I
Q
-------------
N
T
H
A
L
A
P
G
T
-
T
-------
A
P
G
A
T
A
S
T
-
S
L
T
W
G
G
G
D
L
V
A
V
G
N
K
V
A
L
L
P
I
P
--------------------------------------------------------------------------------------------------------------------------------
42
Fugue
56.34
21%
-22
- C1 -
4X0Q
7
DPOLQ_HUMAN
A:
[6-772]
S
L
S
I
I
DVASDQ
N
L
F
Q
T
F
I
K
E
W
R
C
KK
R
F
S
I
S
L
A
C
E
K
I
RDDTLVV
G
L
A
V
C
WGGR
D
A
Y
Y
F
S
LL
D
P
S
L
T
LK
D
R
M
W
Y
L
Q
S
C
L
RKESD
K
E
C
S
V
V
I
YDF
I
Q
S
Y
K
I
L
L
LSCGISLE
Q
S
Y
E
D
P
K
V
A
C
W
L
L
DPDSQEPT
L
H
S
I
V
T
S
FLPHELPLLEGMETSQGIQSLGLNAGSEHSGR
Y
R
A
S
V
E
S
I
L
I
F
N
S
M
N
Q
L
N
S
L
L
Q
K
E
NLQDVFRKV
E
M
P
S
Q
Y
C
L
A
L
L
E
L
N
G
I
G
F
S
T
A
E
C
E
S
Q
K
H
I
M
Q
A
K
L
D
A
I
E
T
Q
A
Y
Q
LAGHSFSFTS
S
D
D
I
A
E
VLFLE
L
K
L
P
PQFSTS
K
D
V
L
N
K
L
K
ALHPLPG
L
I
L
E
W
R
R
I
T
N
A
I
T
KV
V
F
P
L
Q
R
EKCLNPFLG
M
E
R
I
Y
P
V
S
Q
S
----
H
T
A
T
G
R
-------
I
T
F
T
E
P
N
I
Q
N
V
P
R
----------------
D
F
E
I
K
M
G
M
P
F
S
I
-
S
M
R
H
A
F
VP
F
P
G
G
S
I
--------------
L
A
A
-------
D
Y
SQ
L
E
L
R
I
---
L
A
H
L
S
H
D
R
R
L
I
Q
V
L
---
N
T
G
---
A
D
V
F
R
S
I
A
A
E
----
W
-------------------
K
M
I
E
P
E
-
S
V
G
D
------------------------
D
L
R
Q
-------
Q
---
A
K
Q
I
C
Y
G
I
I
Y
G
M
G
A
--
K
S
L
G
E
Q
M
G
I
K
E
N
D
-------------
A
A
C
Y
I
D
S
F
K
-
S
-------
R
Y
T
G
I
N
Q
F
-
M
T
E
T
V
K
N
C
K
R
D
G
F
V
Q
T
I
L
G
R
R
R
Y
L
PGIKDNN
P
Y
R
K
A
H
A
E
R
Q
A
I
N
T
I
V
Q
G
S
A
A
D
I
V
K
I
A
T
V
N
I
Q
K
Q
L
E
T
F
H
STFKS
H
G
H
R
E
G
M
L
Q
S
DC
P
I
R
G
G
F
F
I
LQLHD
E
L
L
Y
E
V
A
EED
V
V
Q
V
A
Q
I
V
K
N
E
M
E
S
AVKLS
V
K
L
K
V
K
V
K
I
G
A
S
W
G
E
L
K
D
F
D
V
39
HHSearch
55.54
8%
-18
- C2 -
3KAN
1
DOPD_HUMAN
A:
[56-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
A
Q
L
S
I
S
S
-
I
G
V
--
V
G
T
A
E
D
N
R
S
H
S
A
H
-------------
F
F
E
F
L
T
K
E
L
-
A
-------
L
-
G
Q
D
R
I
L
-
I
R
F
F
P
L
E
S
W
Q
I
G
K
I
G
T
V
M
T
F
L
---------------------------------------------------------------------------------------------------------------------------------