@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1211: (2015-12-06 )
MTLNAKGESNQILVDKEVHSTNLLLDIDEKPELFQGLLLSFQHVFAMFGATILVPLILGMPVSVALFASGCGTLIYQVATKFKVPVYLGSSFAYITAMALAMKQMHGDISAAQTGILFVGLIYVVVATVIKFVGNSWVDKILPPIIIGPMIIVIGLGLANSAVTNAGFVAKGDWRKMLVAVVTFLIAAFINTKGKGFIKIIPFLFAIIGGYILSIILGLVDLSPVEKAAWFELPKFYLPFKTGLFHSYKLYFGPEMLAILPISIVTIAENIGDHTVLGQICGRNFLKKPGLNRLLIGDGLATAFSALIGGPAETTYGENTGVIGMTRIASVTVIRNAAFIAIAFSFFGKFTALISTIPSAVLGGMAILLYGVIASNGLKVLIENRVNFAEVRNLIIASSMLVLGLGGAVLDLGALTLSGTALSAIVGIILNLILPKESMKS
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------.........10........20........30........40-----.......---.50........60-----.........70........80.....------....90........100---......--...110......-.120.......130-------.-.......140.......150...-----....160.......----170----.......180.------......190.......200.......210...--....220.......230.......240.......250-....-------.....------260.----......270....---------...280------------.....-....290.---......300....--....-.----310........320--...----.--.-..330.......340......--------.----.---350.......360.......370-........380.......390.......400.......410.......420.......430------.......440--------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------MTLNAKGES
N
Q
I
L
V
D
K
EVHST
N
L
L
L
DIDE
K
P
E
L
F
Q
G
L
L
L
S
F
-----
Q
H
V
F
A
M
F
---
G
A
T
I
L
V
P
L
I
LGM------P
V
S
V
A
L
F
AS
G
C
G
T
L
I
Y
Q
V
A
T-KFK
V
P
------
V
Y
LGS
S
F
A
Y
I
T
A
M
A
L
-----
A
M
K
Q
M
H--G
D
I
S
A
A
Q
T
G
I
L
F
-
V
G
L
I
Y
V
V
V
A
T
V
I
K
--------
F
-
V
G
N
S
W
V
D
KIL
P
P
I
IIGP
M
I
I
V
I
G-----LGLANSAVTNA
G
F
V----AK
G
----
D
W
R
K
M
L
V
A
V
V
T
------
F
L
I
A
A
F
INTKGKG
F
I
K
I
I
P
F
L
F
A
I
I
G
G
Y
I
L
S
I
--
I
L
G
LVDLSPV
E
K
A
A
W
FEL
P
K
F
Y
L
PFKTGL
F
H
S
Y
K
L
---
Y
FGP-------
E
M
L
A
I
------
L
P
I
S
----
I
V
T
I
A
E
NIGD
H
T
V
---------
L
G
Q
I
--------------
C
G
R
N
F
-LKKPGL
N
R
---
L
L
IGD
G
L
--
A
T
A
F
--
S
A
L
I-G----GP-AETTYGENTG
V
--
I
G
M
----
T
--
R
-
I
A
S
V
T
V
I
RN
A
A
F
I
A
-
I
A
F
S
F
F
--------
G
----
K
---
F
T
A
L
I
S
T
I
P
S
A
V
L
G
G
M
A
I
L
L
Y
G
--
V
I
ASN
G
L
K
V
L
IENRV
N
F
A
E
V
R
N
L
I
I
A
S
S
M
L
V
LGLG
G
A
V
L
D
L
G
A
L
TL
S
G
T
A
L
S
A
I
V
G
I
I
L
N
L
------IL
P
K
E
SMKS---------------------
6
HHSearch
92.79
39%
-128
- C5 -
3QE7
2
URAA_ECOLI
A:
[4-410]
--------------------------------------------------------------------------------------------------------
R
A
I
G
V
S
E
R
P
P
L
L
Q
T
I
P
L
S
L
-----
Q
H
L
F
A
M
F
---
G
A
T
V
L
V
P
V
L
F
H
I
------
N
P
A
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
-
I
C
K
G
K
I
P
------
A
Y
L
G
S
S
F
A
F
I
S
P
V
L
L
-----
L
L
---
P
--
L
G
Y
E
V
A
L
G
G
F
I
M
-
C
G
V
L
F
C
L
V
S
F
I
-
V
--------
K
K
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
-----
L
E
L
A
G
V
A
A
G
M
A
G
L
L
PAEG
Q
T
P
----
D
S
K
T
I
I
I
S
I
T
T
------
L
A
V
T
V
L
G
S
V
L
F
R
G
F
L
A
I
I
P
I
L
I
G
V
L
V
G
Y
A
L
S
F
--
A
M
G
I
V
D
T
T
P
I
I
N
A
H
W
F
A
L
P
T
L
Y
T
---------
P
R
F
---
E
-
W
F
-------
A
I
L
T
I
------
L
P
A
A
----
L
V
V
I
A
E
H
V
G
H
L
V
V
---------
T
A
N
I
--------------
V
K
K
D
L
-
L
R
D
P
G
L
H
R
---
S
M
F
A
N
G
L
--
S
T
V
I
--
S
G
F
F
-
G
----
S
T
-
P
N
T
T
Y
G
E
N
I
G
V
--
M
A
I
----
T
--
R
-
V
Y
S
T
W
V
I
G
G
A
A
I
F
A
-
I
L
L
S
C
V
--------
G
----
K
---
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
--
V
I
G
A
S
G
I
R
V
L
I
E
S
K
V
D
Y
N
K
A
Q
N
L
I
L
T
S
V
I
L
I
I
G
V
S
G
A
K
V
N
I
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
------
I
F
K
L
I
S
------------------------
16
Fugue
92.70
39%
-128
- C5 -
3QE7
2
URAA_ECOLI
A:
[4-410]
--------------------------------------------------------------------------------------------------------
R
A
I
G
V
S
E
R
P
P
L
L
Q
T
I
P
L
S
L
-----
Q
H
L
F
A
M
F
---
G
A
T
V
L
V
P
V
L
F
H
I
------
N
P
A
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
C
-
K
G
K
I
P
------
A
Y
L
G
S
S
F
A
F
I
S
P
V
L
L
-----
L
L
P
L
-----
G
Y
E
V
A
L
G
G
F
I
M
-
C
G
V
L
F
C
L
V
S
F
I
V
K
--------
K
-
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
-----
L
E
L
A
G
V
A
A
G
M
A
G
L
L
----
P
A
E
GQTP
D
S
K
T
I
I
I
S
I
T
T
------
L
A
V
T
V
L
G
S
V
L
F
R
G
F
L
A
I
I
P
I
L
I
G
V
L
V
G
Y
A
L
S
F
--
A
M
G
I
V
D
T
T
P
I
I
N
A
H
W
F
A
L
P
T
L
Y
T
P
R
-------------
F
E
W
F
-------
A
I
L
T
I
------
L
P
A
A
----
L
V
V
I
A
E
H
V
G
H
L
V
V
---------
T
A
N
I
--------------
V
K
K
D
L
-
L
R
D
P
G
L
H
R
---
S
M
F
A
N
G
L
--
S
T
V
I
--
S
G
F
F
-
G
----
S
T
-
P
N
T
T
Y
G
E
N
I
G
V
--
M
A
I
----
T
--
R
-
V
Y
S
T
W
V
I
G
G
A
A
I
F
A
-
I
L
L
S
C
V
--------
G
----
K
---
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
--
V
I
G
A
S
G
I
R
V
L
I
E
S
K
V
D
Y
N
K
A
Q
N
L
I
L
T
S
V
I
L
I
I
G
V
S
G
A
K
V
N
I
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
------
I
F
K
L
I
S
------------------------
1
PsiBlast_PDB
91.49
39%
-128
- C5 -
3QE7
2
URAA_ECOLI
A:
[4-405]
--------------------------------------------------------------------------------------------------------
R
A
I
G
V
S
E
R
P
P
L
L
Q
T
I
P
L
S
L
-----
Q
H
L
F
A
M
F
---
G
A
T
V
L
V
P
V
L
F
H
I
N-----
P
A
T
V
L
L
F
-
N
G
I
G
T
L
L
Y
L
F
I
C
-
K
G
K
I
P
------
A
Y
L
G
S
S
F
A
F
I
S
P
V
L
L
-----
L
L
P
L
G
Y
-----
E
V
A
L
G
G
F
I
M
-
C
G
V
L
F
C
L
V
S
F
I
V
K
--------
K
-
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
-----
L
E
L
A
G
V
A
A
G
M
A
G
L
L
P---
A
E
G
QTP-
D
S
K
T
I
I
I
S
I
T
T
------
L
A
V
T
V
L
G
S
V
L
F
R
G
F
L
A
I
I
P
I
L
I
G
V
L
V
G
Y
A
L
S
F
--
A
M
G
I
V
D
T
T
P
I
I
N
A
H
W
F
A
L
P
T
L
Y
T
P
-------
R
F
E
W
---
F
----------
A
I
L
T
I
------
L
P
A
A
----
L
V
V
I
A
E
H
V
G
H
L
V
V
---------
T
A
N
I
--------------
V
K
K
D
L
-
L
R
D
P
G
L
H
R
---
S
M
F
A
N
G
L
--
S
T
V
I
--
S
G
F
F
-
G
----
S
T
-
P
N
T
T
Y
G
E
N
I
G
V
--
M
A
I
----
T
--
R
-
V
Y
S
T
W
V
I
G
G
A
A
I
F
A
-
I
L
L
S
C
V
--------
G
----
K
---
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
--
V
I
G
A
S
G
I
R
V
L
I
E
S
K
V
D
Y
N
K
A
Q
N
L
I
L
T
S
V
I
L
I
I
G
V
S
G
A
K
V
N
I
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
------
I
F
K
L
I
S
------------------------
20
Fugue
62.25
21%
-99
* C6 *
3EB8
-
VIRA_SHIFL
A:
[53-399]
-------------------------------------------------------------------------------------------------
A
E
K
H
S
E
K
K
L
M
D
-
S
F
S
P
S
L
S
Q
D
K
M
D
G
------
E
F
A
H
A
N
I
---
D
---------
G
I
------
S
I
R
L
C
L
N
-
K
G
I
C
S
V
F
Y
L
D
G
D
-
K
-------------------
I
Q
S
T
Q
L
-----
S
S
K
E
Y
N
--
N
L
L
S
S
L
P
P
K
Q
F
N
-
L
G
K
V
H
T
I
T
A
P
V
S
------------
G
N
F
K
T
H
K
P
------
A
P
E
V
I
E
T
A
-----
I
N
C
C
T
S
I
I
P
N
D
D
Y
-----------------------------------
F
H
V
K
D
T
D
F
-------------------------------
N
S
V
W
H
D
I
Y
R
D
I
R
A
S
D
S
---
N
S
T
K
I
---
Y
F
N
N
------------------
I
E
I
P
----
L
K
L
I
A
D
L
I
N
E
L
G
I
---------
N
E
F
I
--------------
D
S
K
K
E
-
L
Q
M
--
L
S
Y
---
N
Q
V
N
K
I
I
--
N
S
N
F
--
P
------------------
Q
Q
D
L
C
--
F
Q
T
----
E
--
K
-
L
L
F
T
S
L
F
Q
D
P
A
F
I
S
-
A
L
T
S
A
F
WQSLHITS
S
----
S
---
V
E
H
I
Y
A
Q
I
M
S
E
N
I
E
N
R
L
N
F
M
P
E
Q
R
V
I
N
N
C
G
-
H
I
I
K
I
N
A
V
R
A
Y
E
V
S
S
S
I
L
P
S
H
I
T
C
N
G
V
G
I
N
K
I
E
T
S
Y
L
V
H
A
G
T
L
P
S
--
S
E
G
L
R
N
A
------
I
P
P
E
S
R
Q
V
S
F
A
I
I
S
P
D--------------
22
Fugue
59.74
15%
-120
- C4 -
2J3L
11
SYP_ENTFA
A:
[1-565]
--------------------------MKQSKMLIPTLREVPNDAEV
L
S
H
Q
I
L
L
R
A
GYIRQVAAG
I
Y
S
Y
L
P
L
A
N
R
V
L
E
K
L
K
T
I
M
R
E
E
F
E
K
I
D
A
V
E
M
L
M
P
A
L
L
P
A
E
L
W
K
E
S
G
R
Y
E
T
Y
G
P
N
L
Y
R
L
K
D
RND
R
D
Y
I
L
G
P
T
---
H
E
E
T
F
T
E
L
I
R
D
E
------
I
N
S
Y
K
R
L
P
----
L
N
L
Y
Q
I
Q
T
-
K
Y
R
D
E
KRSRSG
L
L
R
G
R
E
F
I
M
K
D
G
Y
S
F
H
AD
E
A
S
L
D
Q
S
Y
--
R
D
Y
E
K
A
Y
S
R
I
F
E
R
C
G
L
E
F
R
A
I
I
G
D
G
G
--------
A
-
M
G
G
K
D
S
K
E
F
M
A
I
S
E
I
G
E
D
T
I
C
Y
S
TESD
Y
A
A
N
L
E
M
A
T
S
L
Y
T
P
K
----
K
S
H
----
E
T
Q
L
D
L
E
K
I
A
T
P
EVGT
I
A
E
V
A
N
F
F
E
V
E
P
Q
R
I
I
K
S
V
L
F
I
A
D
--
E
E
P
V
M
V
L
--
V
R
G
D
H
D
V
N
D
V
K
L
K
N
F
L
G
A
D
F
L
D
E
A
T
E
E
D
A
R
R
V
L
G
A
GFG
S
I
G
P
VNVSED
V
K
I
Y
A
D
------
L
A
V
Q
D
LAN
A
I
V
G
A
N
E
D
G
Y
H
L
T
NVNPDRDFQ
P
I
S
Y
EDL
R
F
V
Q
EGDPSPD
G
N
G
V
L
-
A
F
T
K
G
I
E
I
G
H
I
F
K
L
G
T
R
Y
--
S
D
A
M
--
G
A
T
V
-
L
----
D
E
-
N
G
R
E
K
S
V
I
M
G
C
Y
G
I
G
V
----
S
--
R
-
L
L
S
A
I
V
E
Q
N
A
D
E
R
G
-
I
N
W
P
T
G
--------
I
----
A
PFD
L
H
V
V
Q
M
N
V
K
D
E
Y
Q
T
K
L
S
Q
E
V
E
A
--
M
M
T
E
A
G
Y
E
V
L
V
D
D
R
----
N
E
R
A
G
V
K
F
A
D
A
D
L
I
G
C
P
-
I
R
I
T
V
G
K
K
A
V
D
G
V
V
E
V
K
I
K
R
T
G
E
M
L
------
E
V
R
K
E
E
L
E
S
T
L
S
I
L
M---------------
17
Fugue
49.71
10%
-130
- C5 -
1Z6T
1
APAF_HUMAN
A:
[1-586]
MD
A
K
A
R
N
C
L
L
Q
H
R
E
A
L
E
K
DIKT
S
Y
I
M
D
H
M
I
S
D
GFLT
I
S
E
E
E
K
V
R
N
EPT
Q
Q
Q
R
A
A
M
L
I
K
M
I
L
K
KD
N
D
S
Y
V
S
F
Y
N
A
L
L
H
E
GY
K
D
L
A
A
L
L
H
D
G
I
P
V
V
G
I
T
S
Y
V
R
T
V
L
C
E
G
G
V
P
Q
R
P
V
V
F
V
T
R
K
K
L
V
-----
N
A
I
Q
Q
K
L
S
K
L
K
G
E
P
G
W
V
T
I
H
G
M
AGCG
K
S
V
L
A
A
E
A
V
R
D
H
S
L
L
E
G
C
F
P
G
G
-
V
H
W
V
S
------
V
G
K
Q
D
K
S
G
L
L
M
K
L
Q
N
-----
L
C
T
R
L
D
--
Q
D
E
S
F
S
Q
R
L
P
L
N
-
I
E
E
A
K
D
R
L
R
I
L
M
L
R
KHPR
S
L
L
I
-
L
D
D
V
W
D
S
W
V
L
K
A
F
D
S
Q
C
Q
I
L
L
T
T
RD---
K
S
V
T
D
S
V
M
G
P
K
Y
V
V
----
P
V
------
E
S
S
L
G
K
E
K
G
L
------
E
I
L
S
L
F
V
N
M
K
K
A
D
L
P
E
Q
A
H
S
I
I
K
E
C
K
G
S
P
L
V
V
S
L
I
G
A
L
L
R
D
F
P
N
R
W
E
Y
Y
L
K
Q
L
Q
N
K
Q
F
K
R
I
R
K
S
S
S
Y
D
Y
------
E
-------
A
L
D
E
A
------
M
S
I
S
----
V
E
M
L
R
E
D
I
K
D
Y
Y
T
---------
D
L
S
I
--------------
L
Q
K
D
V
K
V
P
T
K
V
L
C
I
---
L
W
D
M
E
T
E
E
V
E
D
I
L
--
Q
E
F
V
-
N
K
SL
L
F
C
-
D
R
N
G
K
S
F
R
Y
Y
L
--
H
D
L
----
Q
--
V
-
D
F
L
T
E
K
N
C
S
Q
L
Q
D
L
-
H
K
K
I
I
T
--------
Q
F
Q
R
Y
H
---
Q
P
H
T
L
S
P
D
Q
E
D
C
M
Y
W
Y
N
F
L
A
Y
H
--
M
A
S
A
K
M
H
K
E
L
C
A
L
M
F
S
L
D
W
I
K
A
K
T
E
L
V
G
P
A
H
L
I
H
E
F
V
E
Y
-
R
H
I
L
D
E
K
D
C
A
V
S
E
N
F
Q
E
F
L
S
L
N
GHLLG
R
Q
P
F
P
N
I
V
Q
L
G
L
C
EPETS
E
V
Y
Q
Q
A
K
L
Q
A
K
Q
23
Fugue
48.63
14%
-104
- C6 -
3PND
14
APBE_SALTY
A:
[13-329]
------------------------------------------------------------------------------------------
A
A
Q
V
L
E
G
K
T
M
G
T
L
W
R
V
S
V
V
G
I
D
A
K
R
A
A
E
L
Q
T
K
I
-----
Q
T
Q
L
D
A
D
---
D
W
L
L
S
T
Y
-------------------
K
N
D
S
A
L
M
R
F
N
H
S
-
R
S
L
A
P
------
W
P
V
S
E
A
M
A
D
I
V
T
S
A
L
-----
R
I
G
A
K
T
--
D
G
A
-------------------------------------------
M
D
I
T
V
G
P
L
V
N
L
W
G
-----
F
G
P
D
R
Q
P
L
H
I
P
T
-------
P
A
----
Q
I
D
A
A
K
A
K
T
G
L
------
Q
H
L
Q
V
I
D
R
A
G
H
Q
F
L
Q
K
D
L
P
D
L
Y
----------------
V
D
L
S
T
V
G
E
G
Y
A
A
D
H
L
A
R
L
M
E
Q
E
G
--
I
A
R
Y
L
V
---
S
V
G
G
-------
A
L
S
S
R
G
M
N
AQG
Q
P
W
R
----
V
A
I
Q
K
P
T
D
R
E
N
A
V
---------
Q
A
I
V
D
-------------
I
N
G
H
G
-
I
S
T
S
G
S
Y
R
---
N
Y
Y
E
L
D
--------------
G
----
K
R
-
V
S
H
V
I
D
P
Q
T
G
R
--
P
I
E
----
H
--
N
-
L
V
S
V
T
V
I
A
-----------------------------------
P
T
A
L
E
A
D
G
W
D
T
G
L
M
V
L
G
------------
T
Q
K
A
Q
E
V
V
R
R
E
G
L
---
A
V
F
M
I
M
K
E
G
E
G
F
K
T
W
M
S
P
Q
F
K
T
F
L
V
S
D
--------------------------------------------
19
Fugue
41.43
20%
-98
- C5 -
2NN4
-
YQGQ_BACSU
A:
[1-62]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
T
F
Y
D
V
Q
Q
L
L
K
-
T
F
G
H
I
------
V
Y
F
G
D
R
E
L
E
I
E
F
M
L
D
-----
E
L
K
E
L
Y
M
N
H
M
I
E
K
E
Q
W
A
R
A
A
-
A
V
L
R
K
E
L
E
Q
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
34.74
28%
-77
* C7 *
2DPN
-
?
A:
[186-296]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
T
L
L
F
N
L
H
T
L
---
A
W
D
P
-------
E
L
L
E
A
------
L
G
I
P
----
A
A
L
L
P
E
V
R
P
S
D
G
D
---------
F
G
E
T
--------------
L
P
-
E
L
-
L
G
A
P
V
P
I
R
---
G
V
L
G
D
Q
Q
--
A
A
L
F
G
Q
A
A
L
G
-
G
----
G
E
-
G
K
C
T
Y
G
--
T
G
A
--
F
L
L
----
L
--
N
-
T
G
K
R
P
V
L
S
E
K
G
L
L
A
T
V
A
W
S
L
G
--------
G
----
R
---
A
T
Y
A
L
E
G
S
L
F
V
A
G
A
A
V
G
W
L
K
E
V
--
G
L
I
R
E
S
A
E
V
E
A
L
A
A
S
V
E
D
T
G
D
V
Y
F
V
P
A
F
T
G
L
G
A
P
Y
W
D
P
Y
A
R
G
T
L
L
G
L
T
R
G
T
S
R
A
H
L
A
R
A
A
L
------
E
G
V
A
F
Q
V
R
D
---------------------
21
Fugue
31.25
35%
111
- C5 -
1FH1
-
NODF_RHILV
A:
[5-86]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
L
E
I
I
S
A
I
N
K
L
V
L
G
L
A
D
V
L
W
D
L
E
Q
L
N
I
-
G
D
V
V
E
A
V
R
G
-----------------------------------------
5
PsiBlast_CBE
29.69
37%
-39
- C5 -
4R0C
2
?
C:
[284-336]
------------------------------------------------------------------------------------------------------------------------------------------
G
S
V
L
G
S
P
F
I
H
G
L
------
V
V
I
V
A
L
I
A
G
I
C
G
A
V
Y
G
R
V
S
G
-
Q
F
R
------------
N
S
G
A
V
I
T
A
M
E
V
-----
T
M
A
S
M
A
--
G
Y
L
V
L
M
F
F
A
A
Q
F
-
V
A
W
F
N
Y
S
Q
L
G
L
L
L
--------
A
-
V
K
G
A
A
W
L
G
A
L
T
V
P
K
V
V
L
L
L
L
F
V
V
-----
L
T
A
L
I
N
L
M
I
G
S
A
S
A
----
K
W
S
----
I
L
A
P
V
F
I
P
M
L
M
------
L
L
G
I
S
P
E
A
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
T
P
L
M
P
Y
F
V
L
--
V
L
G
F
A
R
R
Y
Q
P
E
T
G
I
G
T
L
I
A
L
M
L
P
Y
S
L
T
L
L
L
G
W
S
V
L
---
L
G
V
W
-------
I
G
F
G
W
------
P
L
G
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
28.88
17%
1276
- C3 -
1JGN
-
B:
[5-16]
-----------------------------------------------------------------------------------
N
L
N
P
N
A
K
E
F
V
P
G
V
K
Y
G
N
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
28.62
33%
886
- C7 -
3UKW
1
?
C:
[8-22]
----------------------------------------------------------------------------------------------------
R
K
R
P
L
E
W
D
E
D
E
E
P
P
R
K
R
K
R
L
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
28.12
37%
-30
- C5 -
4R0C
3
?
A:
[284-336]
------------------------------------------------------------------------------------------------------------------------------------------
G
S
V
L
G
S
P
F
I
H
G
L
------
V
V
I
V
A
L
I
A
G
I
C
G
A
V
Y
G
R
V
S
G
-
Q
F
R
------------
N
S
G
A
V
I
T
A
M
E
V
-----
T
M
A
S
M
A
--
G
Y
L
V
L
M
F
F
A
A
Q
F
-
V
A
W
F
N
Y
S
Q
L
G
L
L
L
--------
A
-
V
K
G
A
A
W
L
G
A
L
T
V
P
K
V
V
L
L
L
L
F
V
V
-----
L
T
A
L
I
N
L
M
I
G
S
A
S
A
----
K
W
S
----
I
L
A
P
V
F
I
P
M
L
M
------
L
L
G
I
S
P
E
A
S
Q
A
A
Y
R
V
G
D
S
S
T
N
I
I
T
P
L
M
P
Y
F
V
L
--
V
L
G
F
A
R
R
Y
Q
P
E
T
G
I
G
T
L
I
A
L
M
L
P
Y
S
L
T
L
L
L
G
W
S
V
L
---
L
G
V
W
-------
I
G
F
G
W
------
P
L
G
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
26.60
30%
95
* C5 *
1VF5
1
PETM_MASLA
F:
[1-33]
--------------------------------------------------------------------------------------------------------------
M
T
E
E
M
L
Y
A
A
L
L
S
F
-----
G
L
I
F
V
G
W
---
G
L
G
V
L
L
L
K
I
Q
G
A
------
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
26.25
17%
-29
- C5 -
3QE7
2
URAA_ECOLI
A:
[44-145]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
T
---
V
L
L
F
N
G
I
--
G
T
L
L
--
Y
L
F
I
C
K
----
G
K
I
P
A
Y
L
-
G
S
S
F
A
F
--
I
S
P
V
L
L
L
L
PL
G
Y
E
V
A
L
G
G
F
I
M
C
G
V
L
F
-
C
L
V
S
F
I
--------
V
----
K
K
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
L
--
E
L
A
G
V
A
A
G
M
A
G
L
L
P
A
E
G
Q
T
P
D
S
K
T
I
I
I
S
I
T
T
L
A
V
T
V
L
G
S
V
L
F
R
G
F
L
A
I
I
P
I
L
I
G
V
L
V
G
Y
A
L
------
S
F
A
M
G
I
V
D
T
---------------------
13
HHSearch
25.24
31%
851
- C7 -
2QTV
-
D:
[25-40]
------------------------------------------------------------------------------------------------------
N
D
L
P
L
K
V
K
E
K
P
S
R
A
K
A
V
S
V
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
24.92
36%
916
- C2 -
2D11
-
NHRF2_HUMAN
E:
[16-26]
----------------------------------------------------------------------------------
M
D
W
N
R
K
R
E
I
F
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
24.07
25%
817
- C5 -
2D10
-
NHRF1_HUMAN
E:
[16-27]
----------------------------------------------------------------------------------
M
D
W
S
K
K
N
E
L
F
S
N
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
18.51
25%
273
- C5 -
3MP7
-
SECE_PYRFU
B:
[24-48]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
N
W
A
T
Y
K
R
---
A
A
K
I
T
G
L
--
G
I
I
L
--
I
G
L
I
-
G
----
M
L
-
I
R
I
V
G
I
L
I
L
G
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------