@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1233: (2015-12-06 )
MKPICIIPARSGSKGLPDKNMLFLAGKPMIFHTIDAAIESGMFDKKDIFVSTDSELYREICLERGISVVMRKPELSTDQATSYDMLKDFLSDYEDNQEFVLLQVTSPLRKSWHIKEAMEYYSSHDVDNVVSFSEVEKHPGLFTTLSDKGYAIDMVGADKGYRRQDLQPLYYPNGAIFISNKETYLREKSFFTSRTYAYQMAKEFSLDVDTRDDFIHVIGHLFFDYAIREKENKVFYKEGYSRLFNREASKIILGDSKTISISLENYHNYSQGGVTLATMLENLPNFLTANVTEAFVSIGVNDLITGYSVEEIFSNFQKLYSLLAENKIKMRFTTIAYTLFRETVNNADIEKINQWLTEFCYQNQIPLLDINRFLSKDGNLNYHLTSDGLHFTQEANDLLQSQYQLFVDEVKTL
Atome Classification :
(20 SA)
.........10......------..20........30........40........50.....---...60.---.......70........80.......--.90..--.--.....100........110.......120......---.130-....------.---..------..-140.------.-....-.150--..--.---....------.160.------..------.------....170.......180......-----------------.------------------190.......-..200.-.......210.......220.......230.......240.......250--.----........260--------...----------..------------....------------------------------270.......280..-.-....290--..--....--.300....----.---..310.......320...--.--...330...--....340.-------------......350.......360.-.-.....370-.-.......380......-----------.390.......400.......410.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MK
P
I
C
I
I
PARSGSKGLP------DK
N
M
L
F
LAGK
P
M
I
F
H
T
I
D
A
A
I
E
SGMFDKK
D
I
F
VS
T
D
S
E
L
---
Y
R
E
I
C
L
---ER
G
I
S
V
V
M
RKPELSTDQAT
S
Y
D
M
L
K
D
--
F
L
S
DY--E--DNQ
E
F
V
-
L
L
Q
VT
S
P
L
R
KSW
H
I
K
E
A
M
E
Y
Y
SSHDV
D
N
---
V
V
---
S
F
S
E
------
V
---
E
K------HP-G
L
F
T
------T-LSDK-
G
Y
A
---
I
D
--
M
---VGAD------KGY-R------RQ------D------LQPLYYPN
G
A
I
F
ISN
K
E
T
Y
L
R
EK-----------------S------------------F--FTS
R
T
Y
A
-
Y
Q
M
A
-
K
-
E
FSLDVDTR
D
D
F
I
H
V
I
G
H
L
F
F
D
Y
A
IREKENK
V
F
Y
K
E
G
Y
S
R
L
F
NREA
S
K
----
I
----
I
LGDS
K
T
I
S
----------
I
S
L----------EN------------YHNY------------------------------SQG
G
V
T
L
A
T
M
L
E
N
L
P
-
N
-
F
L
T
A
N
V
T
--
E
A
--
F
V
S
I--G
V
N
D
LITG----Y---
S
V
E
E
I
F
S
N
F
Q
K
L
Y
S
L
L
AE--N--
K
I
K
M
R
F
T
T
I
--
A
Y
T
L
F
R
E
T-------------VNNA
D
I
E
K
I
N
Q
W
L
T
E
F
C
Y
QN-Q-IP
L
L
D
I
-
N
-
R
-
F
LSKDGN
L
N
Y
H
LTSDG-----------
L
H
F
T
Q
E
A
N
D
L
L
Q
S
Q
Y
Q
L
F
V
D
E
VKTL
1
PsiBlast_PDB
93.41
37%
-94
- C2 -
1EYR
1
NEUA_NEIME
A:
[6-216]
---
I
A
V
I
L
A
R
Q
N
S
K
G
L
P
------
L
K
N
L
R
K
M
N
G
I
S
L
L
G
H
T
I
N
A
A
I
S
S
K
C
F
D
R
--
I
I
V
S
T
D
G
G
L
---
I
A
E
E
A
K
---
N
F
G
V
E
V
V
L
R
P
A
E
L
A
S
D
T
A
S
S
I
S
G
V
I
H
--
A
L
E
T
I
--
G
--
S
N
S
G
T
V
T
L
L
Q
P
T
S
P
L
R
T
G
A
H
I
R
E
A
F
S
L
F
D
E
K
I
K
G
S
---
V
V
---
S
A
C
P
------
M
---
E
H
------
H
P
L
K
T
L
L
------
Q
-
I
N
N
G
-
E
Y
A
---
P
M
--
R
---
H
L
S
D
------
L
E
Q
-
P
------
R
Q
------
Q
------
L
P
Q
A
F
R
P
N
G
A
I
Y
I
N
D
T
A
S
L
I
A
N
N
-----------------
C
------------------
F
--
F
I
A
P
T
K
L
-
Y
I
M
S
-
H
-
Q
D
S
I
D
I
D
T
E
L
D
L
Q
Q
A
E
N
I
L
N
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
81.19
23%
-77
- C2 -
3TQD
2
KDSB_COXBU
A:
[9-256]
-
E
F
R
V
I
I
P
A
R
F
D
---
L
P
------
G
K
A
L
V
D
I
A
G
K
P
M
I
Q
H
V
Y
E
S
A
I
K
S
G
-
A
E
E
--
V
V
I
A
T
D
D
K
R
---
I
R
Q
V
A
E
---
D
F
G
A
V
V
C
M
T
S
S
D
H
Q
S
G
T
E
R
I
A
E
A
A
V
A
--
L
G
F
----
E
--
D
D
E
I
I
V
-
C
L
Q
G
D
E
P
L
I
P
P
D
A
I
R
K
L
A
E
D
L
D
E
H
D
--
K
---
V
A
---
S
L
C
T
P
I
TE
V
D
E
---
L
F
------
N
P
-
H
S
T
K
------
V
-
V
L
N
R
-
R
N
Y
---
A
L
--
Y
---
F
S
H
A
------
P
I
P
-
W
------
G
R
DTFSDK
E
N
L
Q
---
L
N
G
S
H
Y
R
H
V
G
I
Y
A
Y
R
V
G
F
L
E
E
Y
L
S
W
D
A
C
P
A
E
K
M
E
AL
E
Q
L
R
I
------------------
L
W
-
H
G
G
R
I
H
M
-
V
V
A
K
-
S
-
K
C
P
P
G
V
D
T
E
E
D
L
E
R
V
R
A
Y
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
79.44
28%
-92
- C2 -
1QWJ
1
NEUA_MOUSE
A:
[6-213]
----
A
L
V
L
A
R
G
G
S
K
G
I
P
------
L
K
N
I
K
R
L
A
G
V
P
L
I
G
W
V
L
R
A
A
L
D
A
G
V
F
--
Q
S
V
W
V
S
T
D
H
D
E
---
I
E
N
V
A
K
---
Q
F
G
A
Q
V
H
R
R
S
S
E
T
S
K
D
S
S
T
S
L
D
A
I
V
E
--
F
L
N
Y
H
--
N
--
E
V
D
I
V
G
-
N
I
Q
A
T
S
P
C
L
H
P
T
D
L
Q
K
V
A
E
M
I
R
E
E
G
Y
D
S
---
V
-----
F
S
V
------
V
---
R
R
------
H
Q
-
F
R
W
S
------
E
-
I
Q
K
G
-
V
R
E
---
V
T
--
E
P
LN
L
N
P
A
------
K
R
P
-
R
------
R
Q
------
D
------
W
D
G
E
L
Y
E
N
G
S
F
Y
F
A
K
R
--
H
L
I
E
M
-----------------
G
------------------
Y
--
L
Q
G
G
K
M
A
Y
Y
E
M
R
-
A
-
E
H
S
V
D
I
D
V
D
I
D
W
P
I
A
E
Q
R
V
L
R
F
G
Y
F
G
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
77.75
23%
-91
- C2 -
1QWJ
1
NEUA_MOUSE
A:
[2-223]
P
H
L
A
A
L
V
L
A
R
G
G
S
K
G
I
P
------
L
K
N
I
K
R
L
A
G
V
P
L
I
G
W
V
L
R
A
A
L
D
A
G
V
F
Q
S
--
V
W
V
S
T
D
H
D
E
---
I
E
N
V
A
K
---
Q
F
G
A
Q
V
H
R
R
S
S
E
T
S
K
D
S
S
T
S
L
D
A
I
V
E
--
F
L
N
Y
H
--
N
--
E
V
D
I
V
G
-
N
I
Q
A
T
S
P
C
L
H
P
T
D
L
Q
K
V
A
E
M
I
R
E
E
-
G
Y
D
---
S
V
---
F
S
V
V
------
R
---
R
H
-------
Q
-
F
R
W
S
------
E
---
I
Q
-
K
G
V
R
E
V
T
E
P
L
N
---
L
N
P
-------
A
K
R
-
P
------
R
R
------
Q
D-----
W
D
G
E
L
Y
E
N
G
S
F
Y
F
A
K
R
H
L
I
E
M
-
G
-----------------
Y
------------------
L
--
Q
G
G
K
M
A
Y
-
Y
E
M
R
-
A
-
E
H
S
V
D
I
D
V
D
I
D
W
P
I
A
E
Q
R
V
L
R
F
G
Y
F
G
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
74.20
22%
-80
- C2 -
1VIC
-
KDSB_HAEIN
A:
[2-254]
-
S
F
T
V
I
I
P
A
R
F
A
S
S
R
L
P
------
G
K
P
L
A
D
I
K
G
K
P
M
I
Q
H
V
F
E
K
A
L
Q
S
G
-
A
S
R
--
V
I
I
A
T
D
N
E
N
---
V
A
D
V
A
K
---
S
F
G
A
E
V
C
M
T
S
V
N
H
N
S
G
T
----
E
R
L
A
E
--
V
V
E
K
L
--
A
IP
D
N
E
I
I
V
-
N
I
Q
G
D
E
P
L
I
P
P
V
I
V
R
Q
V
A
D
N
L
A
K
F
-
N
V
N
---
M
A
S
L
A
V
K
I
H
------
D
---
A
E
E
L
----
F
N
-
P
N
A
V
K
-----
V
-
L
T
D
K
-
D
G
Y
---
V
L
--
Y
---
F
S
R
S
VIPYDR
D
Q
F
-
M
------
N
L
------
Q
DVQK
V
Q
L
S
D
A
Y
L
R
H
I
G
I
Y
A
Y
R
A
G
F
I
K
Q
Y
V
-----------------
Q
WAPT
Q
L
E
N
L
E
KL
E
Q
L
R
V
-
L
Y
-
N
G
E
R
I
H
--
V
E
L
A
-
K
E
V
P
A
V
G
V
D
T
A
E
D
L
E
K
V
R
A
I
L
A
A
N
G
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
69.31
19%
-69
- C2 -
3K8D
4
KDSB_ECOLI
A:
[18-263]
-
S
F
V
V
I
I
P
A
R
Y
A
S
T
R
L
P
------
G
K
P
L
V
D
I
N
G
K
P
M
I
V
H
V
L
E
R
A
R
E
S
G
-
A
E
R
--
I
I
V
A
T
D
H
E
D
---
V
A
R
A
V
E
---
A
A
G
G
E
V
C
M
T
R
A
D
H
Q
S
G
T
E
R
L
----
A
E
--
V
V
E
K
C
--
A
FS
D
D
T
V
I
V
-
N
V
Q
G
D
E
P
M
I
P
A
T
I
I
R
Q
V
A
D
N
L
A
Q
R
-
Q
V
G
---
M
A
---
T
L
A
V
------
P
I
HN
A
E
------
E
A
-
F
N
P
N
A
V
K
---
V
-
V
L
D
A
-
E
G
Y
---
A
L
--
Y
---
F
S
R
A
------
T
I
P
-
W
DR
D
R
F
A
E
G
------
L
ET----
V
G
D
N
F
L
R
H
L
G
I
Y
G
Y
R
A
G
F
I
R
R
Y
V
N
WQPS
P
L
E
H
I
E
MLE---
Q
L
R
V
---------------
L
W
-
Y
G
E
K
I
H
V
-
A
V
A
Q
-
E
-
V
P
G
T
G
V
D
T
P
E
D
L
E
R
V
R
A
E
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
67.96
17%
-84
- C2 -
1H7E
-
KPSU5_ECOLX
A:
[1-240]
S
K
A
V
I
V
I
P
A
R
Y
G
S
S
R
L
P
------
G
K
P
L
L
D
I
V
G
K
P
M
I
Q
H
V
Y
E
R
A
L
Q
V
A
G
V
A
E
--
V
W
V
A
T
D
D
P
R
---
V
E
Q
A
V
Q
---
A
F
G
G
K
A
I
M
T
R
N
D
H
E
S
G
T
D
----
R
L
V
E
--
V
M
H
K
V
--
E
---
A
D
I
Y
I
-
N
L
Q
G
D
E
P
M
I
R
P
R
D
V
E
T
L
L
Q
G
M
R
D
D
-
P
A
L
---
P
V
---
A
T
L
C
H
A
I
S
A
A
E
---
A
A
------
E
P
-
S
T
V
K
------
V
-
V
V
N
T
-
R
Q
D
---
A
L
--
Y
---
F
S
R
S
------
P
I
P
-
Y
------
P
R
N-----
A
------
E
K
A
R
Y
L
K
H
V
G
I
Y
A
Y
R
R
D
V
L
Q
N
Y
S
-----------------
Q
LPES
M
P
E
Q
A
E
SL
E
Q
L
R
L
-
M
N
-
A
G
I
N
I
R
T
-
F
E
V
A
---
A
T
G
P
G
V
D
T
P
A
C
L
E
K
V
R
A
L
M
A
Q
E
L
A
E
N
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
67.09
20%
-82
- C2 -
2Y6P
5
KDSB_AQUAE
A:
[2-232]
-
R
R
A
V
I
I
P
A
R
L
G
S
T
R
L
K
------
E
K
P
L
K
N
L
L
G
K
P
L
I
R
W
V
V
E
G
L
V
K
T
G
--
E
R
--
V
I
L
A
T
D
S
E
R
---
V
K
E
V
V
E
---
D
L
-
C
E
V
F
L
T
P
S
D
L
P
S
G
S
D
----
R
V
L
Y
--
V
V
R
D
L
-----
D
V
D
L
I
I
-
N
Y
Q
G
D
E
P
F
V
Y
E
E
D
I
K
L
I
F
R
E
L
E
K
G
---
E
---
R
V
---
V
T
L
A
------
R
---
K
D
------
K
E
-
A
Y
E
R
PE
D
V
K
-
V
-
V
L
D
R
-
E
G
Y
---
A
L
--
Y
---
F
S
R
S
------
P
I
P
-
Y
------
F
R
K-----
N
------
D
T
F
Y
P
L
K
H
V
G
I
Y
G
F
R
K
E
T
L
M
E
F
G
-----------------
A
MPPS
K
L
E
Q
I
E
GL
E
Q
L
R
--
L
L
E
N
G
I
K
I
K
V
-
L
I
T
--
E
-
N
Y
Y
H
G
V
D
T
E
E
D
L
K
I
V
E
E
K
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
66.84
18%
-73
- C2 -
3OAM
1
KDSB_VIBCH
A:
[1-250]
M
S
F
T
V
V
I
P
A
R
Y
Q
S
T
R
L
P
------
G
K
P
L
A
D
I
G
G
K
P
M
I
Q
W
V
Y
E
Q
A
M
Q
A
G
-
A
D
R
--
V
I
I
A
T
D
D
E
R
---
V
E
Q
A
V
Q
---
A
F
G
G
V
V
C
M
T
S
P
N
H
Q
S
G
T
E
R
L
A
E
V
V
A
K
--
M
A
--
I
--
P
--
A
D
H
I
V
V
-
N
V
Q
G
D
E
P
L
I
P
P
A
I
I
R
Q
V
A
D
N
L
A
A
C
-
S
A
P
---
M
A
---
T
L
A
V
------
E
---
I
E
D
E
A
E
V
F
N
P
-
N
A
V
K
------
V
-
I
T
D
K
-
S
G
Y
---
A
L
--
Y
---
F
S
R
A
------
T
I
P
W
D
------
R
D
N
F
A
---
K
ADKA--
I
V
Q
P
L
L
R
H
I
G
I
Y
A
Y
R
A
G
F
I
N
T
Y
L
D
WQPS
Q
L
E
K
I
E
CLEQ--
L
R
V
L
---------------
W
--
H
G
E
K
I
H
V
-
A
V
A
L
-
E
-
A
P
P
A
G
V
D
T
P
E
D
L
E
V
V
R
R
I
V
A
E
R
A
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
66.34
17%
-93
* C2 *
3P94
1
?
A:
[20-203]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
----
V
P
S
N
V
V
F
M
G
----------
N
S
I
----------
T
D
------------
G
W
W
P
ADST
F
F
I
R
N
NFVDR----------------
G
I
S
G
Q
T
T
S
E
M
L
V
R
F
R
Q
D
-
V
I
N
L
K
P
K
--
A
V
--
V
I
L
A
--
G
I
N
D
I
A
H
N
----
N
GVI
A
L
E
N
V
F
G
N
L
V
S
M
A
E
L
A
K
A
--
N
--
H
I
K
V
I
F
C
S
V
--
L
P
A
Y
D
F
P
W
RPGM---------
Q
P
A
D
K
V
I
Q
L
N
K
W
I
K
E
Y
A
D
K
N
-
G
-
L
T
Y
V
D
Y
-
H
S
A
-
M
K
D
E
R
N
G
L
P
A
N
L
S
K
D
G
-----------
V
H
P
T
L
E
G
Y
K
I
M
E
K
I
V
L
E
A
I
H
K
T
V
K
-
30
HHSearch
63.95
20%
-91
- C2 -
2HSJ
4
?
A:
[19-214]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
Q
T
K
Y
R
H
L
N
H
I
S
----
V
----
V
E
P
N
I
L
F
I
G
----------
D
S
I
----------
V
E
------------
Y
Y
P
L
QELFGTS
K
T
I
V
N
R-----------------
G
I
R
G
Y
Q
T
G
L
L
L
E
N
L
D
A
H
-
L
Y
G
G
A
V
D
--
K
I
--
F
L
L
I
--
G
T
N
D
I
G
K
D
----
V
---
P
V
N
E
A
L
N
N
L
E
A
I
I
Q
S
V
A
R
--
D
Y
P
L
T
E
I
K
L
L
S
I
--
L
P
V
N
E
R
E
E
YQQAVYI------
R
S
N
E
K
I
Q
N
W
N
Q
A
Y
Q
E
L
A
S
A
Y
M
Q
-
V
E
F
V
P
V
-
F
D
C
-
L
T
D
Q
A
G
Q
L
K
K
E
Y
T
T
D
G
-----------
L
H
L
S
I
A
G
Y
Q
A
L
S
K
S
L
K
D
Y
L
Y
-----
56
Fugue
63.91
15%
-66
- C2 -
1H7E
-
KPSU5_ECOLX
A:
[1-245]
S
K
A
V
I
V
I
P
A
R
Y
G
S
S
R
L
P
------
G
K
P
L
L
D
I
V
G
K
P
M
I
Q
H
V
Y
E
R
A
L
Q
V
A
G
V
A
--
E
V
W
V
A
T
D
D
P
R
---
V
E
Q
A
V
Q
---
A
F
G
G
K
A
I
M
T
R
N
D
H
E
S
G
T
D
R
L
V
E
V
M
H
K
--
V
---------
E
A
D
I
Y
I
-
N
L
Q
G
D
E
P
M
I
R
P
R
D
V
E
T
L
L
Q
G
M
R
D
D
P
A
L
P
---
V
A
---
T
L
C
H
------
A
---
I
S
------
A
A
-
E
A
A
E
PS
T
V
K
V
V
-
V
N
T
R
-
Q
D
A
---
L
Y
--
F
---
S
R
S
P
------
I
P
Y
-
P
------
R
N
------
A
------
E
K
A
R
Y
L
K
H
V
G
I
Y
A
Y
R
R
D
V
L
Q
N
Y
S
-----------------
Q
------------------
L
--
P
E
S
M
P
E
Q
-
A
E
S
L
-
E
-
Q
--
L
R
L
M
N
A
G
I
N
I
R
T
F
E
V
A
A
T
G
P
G
V
D
T
P
A
C
L
E
K
V
R
A
L
M
A
Q
E
L
A
E
N
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
61.60
17%
-90
- C2 -
3MIL
1
IAH1_YEAST
A:
[3-211]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
E
K
F
L
L
F
G
----------
D
S
I
----------
T
E
------------
F
A
F
N
TRPIEDG
K
D
Q
Y
A
L
G
A
A
L
V
N
E
Y
TRK
M
D
I
L
Q
R
G
F
K
G
Y
T
S
R
W
A
L
K
I
L
P
-
E
-
I
L
K
H
E
S
N
--
I
V
M
A
T
I
F
L
--
G
A
N
D
A
C
S
A
GPQS
V
---
P
L
P
E
F
I
D
N
I
R
Q
M
V
S
L
M
K
S
--
Y
--
H
I
R
P
I
I
I
G
P
--
G
L
V
D
R
E
K
W
E
K
E
K
S
E
E
I
A
L
GYF
R
T
N
E
N
F
A
I
Y
S
D
A
L
A
K
L
A
N
E
E
-
K
-
V
P
F
V
A
L
-
N
K
A
-
F
Q
Q
E
G
G
D
A
W
Q
Q
L
L
T
D
G
-----------
L
H
F
S
G
K
G
Y
K
I
F
H
D
E
L
L
K
V
I
E
T
F
Y
P
Q
6
PsiBlast_PDB
61.55
26%
-106
- C2 -
1VIC
-
KDSB_HAEIN
A:
[5-153]
----
V
I
I
P
A
R
F
A
S
S
R
L
P
------
G
K
P
L
A
D
I
K
G
K
P
M
I
Q
H
V
F
E
K
A
L
Q
S
G
---
A
S
R
V
I
I
A
T
D
N
E
N
---
V
A
D
V
A
K
---
S
F
G
A
E
V
C
M
----
T
S
V
N
H
N
S
G
T
E
R
L
A
E
--
V
V
E
K
L
AI
P
--
D
N
E
I
I
V
-
N
I
Q
G
D
E
P
L
I
P
P
V
I
V
R
Q
V
A
D
N
L
A
K
F
N
V
N
M
A
S
L
A
V
---
K
I
H
D
------
A
---
E
E
L
F
----
N
P
-
N
A
V
K
------
V
-
L
T
D
K
D
G
Y
V
---
L
Y
--
F
---
S
R
S
V
------
I
P
Y
-
D
------
R
D
------
Q
------
F
M
N
L
Q
D
V
Q
K
V
Q
L
S
D
A
Y
L
R
H
I
G
I
Y
-----------------
A
------------------
Y
--
R
A
G
F
I
K
Q
-
Y
V
Q
W
-
A
-
P
T
Q
L
E
N
L
E
K
L
E
Q
L
R
V
L
Y
N
G
E
R
I
H
V
E
L
A
K
E
V
P
A
V
G
V
D
T
A
E
D
L
E
K
V
R
A
I
L
----
A
----
A
N
G
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
60.69
16%
-74
- C2 -
1LVW
8
?
A:
[2-243]
A
H
M
K
G
I
V
L
A
G
G
S
G
T
R
L
Y
PITRAV
S
K
Q
L
L
P
I
Y
D
K
P
M
I
Y
Y
P
L
S
V
L
M
L
A
G
-
I
R
D
--
I
L
I
I
S
T
P
R
D
L
P
L
Y
R
D
L
L
G
DGS
Q
F
G
V
R
F
S
Y
R
V
Q
E
E
P
R
G
I
A
---
D
A
F
I
V
--
G
K
D
F
I
--
G
---
D
S
K
V
A
-
L
V
L
G
D
N
V
F
Y
G
H
-
R
F
S
E
I
L
R
R
A
A
S
L
-
E
D
G
---
A
V
---
I
F
G
Y
------
Y
---
V
R
------
D
P
-
R
P
F
G
------
V
V
E
F
D
S
-
E
G
R
---
V
I
--
S
---
I
E
E
K
------
P
S
------------------------
R
P
K
S
N
Y
V
V
P
G
L
Y
F
Y
D
N
Q
V
V
E
I
A
R
-----------------
R
IEPSDRGELE
I
T
S
V
N
E
E
Y
L
--
R
M
G
K
L
R
V
-
E
L
M
G
R
G
-
M
A
W
L
D
T
G
T
H
D
G
L
L
E
A
S
S
F
I
E
T
I
Q
K
R
Q
G
F
Y
I
A
C
L
E
E
I
A
Y
N
N
G
W
I
T
R
E
D
V
----
L
----
E
M
A
E
K
L
E
K
T
----------
D
Y
G
----------
K
Y
------------
L
R
D
L
------------------------------
A
E
G
N
F
H
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
60.25
14%
-86
- C2 -
3HP4
-
?
A:
[2-183]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
T
I
L
I
L
G
----------
D
-
L
----------
S
A
------------
A
Y
G
L
QQEEG
W
V
K
L
L
Q
D
K
Y
D
A
E
QSD
I
V
L
I
N
A----
S
I
S
G
E
T
S
G
G
A
L
R
R
L
D
-
A
L
L
E
Q
Y
E
P
T
--
H
V
--
L
I
E
L
--
G
A
N
D
G
L
R
G
----
F
---
P
V
K
K
M
Q
T
N
L
T
A
L
V
K
K
S
Q
A
--
A
--
N
A
M
T
A
L
M
E
I
--
Y
I
P
P
N
----------------
Y
G
P
R
Y
S
K
M
F
T
S
S
F
T
Q
I
S
E
D
T
-
N
-
A
H
L
M
N
F
-
F
M
L
-
D
I
A
G
K
---
S
D
L
M
Q
N
D
S
-----------
L
H
P
N
K
K
A
Q
P
L
I
R
D
E
M
Y
D
S
I
K
K
W
L
N
N
49
Fugue
60.13
15%
-70
- C2 -
1FXW
1
PA1B3_BOVIN
A:
[5-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
P
A
S
K
P
T
P
V
Q
D
V
Q
G
D
G
R
W
M
S
L
H
H
R
F
V
A
D
S
K
D
K
EPE
V
V
----
F
I
G
D
S
L
V
Q
L
MHQCEIWREL
F
S
P
----------
L
H
------------
A
L
N
F
------------------------------
G
I
G
G
D
S
T
Q
H
V
L
W
R
L
E
-
N
-
G
E
L
E
H
I
R
PK
I
V
--
V
V
W
V
--
G
T
N
N
--
H
G
----
H
---
T
A
E
Q
V
T
G
G
I
K
A
I
V
Q
L
V
N
E
--
R
QP
Q
A
R
V
V
V
L
G
L
--
L
P
R
G
Q
H
P
N
-------------
P
L
R
E
K
N
R
R
V
N
E
L
V
R
A
A
L
A
G
H
-
P
R
A
H
F
L
D
A
-
D
-
P
G
F
V
H
S
D
G
T
I
S
H
H
D
M
Y
D
Y
-----------
L
H
L
S
R
L
G
Y
T
P
V
C
R
A
L
H
S
L
L
L
R
L
---
50
Fugue
60.08
13%
-86
- C2 -
5A4A
6
?
A:
[1-208]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
H
T
S
G
T
Y
N
D
S
L
L
T
I
N
S
D
Y
D
A
Y
----
L
LD
F
P
L
M
G
D
D
F
M
L
Y
----------
L
A
R
----------
M
E
LKCRFRRHERVL
Q
S
G
L
------------------------------
C
V
S
G
L
T
I
N
G
A
R
N
R
L
K
-
R
-
V
Q
L
P
E
G
T
--
Q
I
--
I
V
N
I
--
G
S
V
D
I
M
R
G
----
K
---
P
L
V
Q
I
E
H
D
F
R
L
L
I
K
E
M
H
N
--
M
--
R
L
V
P
I
L
T
N
L
AP
L
G
N
Y
C
H
D
K
-------------
V
L
C
D
K
I
Y
R
F
N
K
F
I
R
S
E
C
--
C
-
H
-
L
K
V
I
D
I
H
S
-
C
-
L
I
N
E
R
G
V
V
R
F
D
C
F
Q
A
S
P
R
Q
V
TGSK
E
P
Y
L
F
W
N
K
I
G
R
Q
R
V
L
Q
V
I
E
T
S
L
E
Y
----
51
Fugue
59.95
18%
-70
- C2 -
1FXW
-
PA1B2_BOVIN
F:
[6-217]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
P
A
A
I
P
H
A
A
E
D
I
Q
G
D
D
R
W
M
S
Q
H
N
R
F
V
L
D
C
K
D
K
EPDV
L
----
F
V
G
D
S
M
V
Q
L
----------
M
Q
Q
YEIWRELFSP
L
H
------------
A
L
N
F
------------------------------
G
I
G
G
D
T
T
R
H
V
L
W
R
L
K
-
N
-
G
E
L
E
N
I
K
--
P
K
--
V
I
V
V
WV
G
T
N
N
H
--
E
----
N
---
T
A
E
E
V
A
G
G
I
E
A
I
V
Q
L
I
N
T
RQ
P
--
Q
A
K
I
I
V
L
G
L
--
L
P
R
G
E
K
P
N
-------------
P
L
R
Q
K
N
A
K
V
N
Q
L
L
K
V
S
L
P
K
L
-
A
N
V
Q
L
L
D
T
-
D
-
G
G
F
V
H
S
D
G
A
I
S
C
H
D
M
F
D
F
-----------
L
H
L
T
G
G
G
Y
A
K
I
C
K
P
L
H
E
L
I
M
Q
L
L
--
5
PsiBlast_PDB
59.58
30%
-108
- C2 -
3TQD
1
KDSB_COXBU
A:
[13-135]
-----
I
I
P
A
R
F
D
---
L
P
------
G
K
A
L
V
D
I
A
G
K
P
M
I
Q
H
V
Y
E
S
A
I
K
S
G
A
---
E
E
V
V
I
A
T
D
D
K
R
---
I
R
Q
V
A
E
---
D
F
G
A
V
V
C
M
----
T
S
S
D
H
Q
S
G
T
E
R
I
A
E
A
A
V
A
L
G
F
--
E
--
D
D
E
I
I
V
-
C
L
Q
G
D
E
P
L
I
P
P
D
A
I
R
K
L
A
E
D
L
D
E
H
D
--
K
---
V
A
---
S
L
C
T
------
P
---
I
T
------
E
V
-
D
E
L
F
------
N
-
P
H
S
T
-
K
V
V
---
L
N
--
R
---
R
N
Y
A
------
L
Y
F
-
S
------
H
A
------
P
------
I
P
W
G
R
D
T
F
S
D
K
E
N
L
Q
L
N
G
S
H
Y
R
H
-----------------
V
------------------
G
--
I
Y
A
Y
R
V
G
-
F
L
E
E
-
Y
-
L
S
W
D
A
C
P
A
E
K
M
E
A
L
E
Q
L
R
I
L
W
H
G
G
R
I
H
M
V
V
A
K
S
K
C
P
P
G
V
D
T
E
E
D
L
E
R
V
----
R
----
A
Y
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------