@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1264: (2015-12-06 )
MSETVKLFQYSTLSSLMAGLYKGSLTIGELLTHGDLGIGTVHMIDGELIVLDGKAYQAIGTDGKAEIIQLSDDVTVPYAAVLPHYIQKQFDINAETDNKDLEEMILKNFEGQNLFKSLKIKGTFSRMHVRMIPKSPQHKRFADIASNQPEFTRENVSGTLVGIWTPELFHGVGVKGFHVHFISDDLTFGGHVMDYSLTQGKVEIGKVDQLDQCFPTQDQEFLEANFDLQKLREDIDLSE
Atome Classification :
(20 SA)
.........10........20-.......------.30.....----....-40-----...------------.....50..---.--.....60........70........-80........90........-------100.......110..-.-.-...120..------------.......130.-....--..----140...--....150.......160.---....-----..170-....-.-...----------.180..--.---..-..190....-.--..200..-.-....210.......-220.......230.......-------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSE
T
V
K
L
F
Q
Y
S
T
L
S
S
L
M
A
G
L
Y-KGSL
T
I
G
------
E
L
-
L
THGD----LG
I
G
-
T
V
-----
H
M
I------------DG
E
L
I
V
LDG---K--
A
Y
Q
A
IGTDG
K
A
E
I
I
Q
LSDDVTV
P
Y
A
-
A
V
L
P
H
Y
I
Q
K
Q
FDINAETDN
K
-------
D
L
E
E
M
I
L
K
NFE
G
Q
N
L
-
F
-
K
-
S
LKI--
K
G
------------
T
F
S
R
M
H
V
R
MIP-KSPQ--
H
K
----
R
F
A
D
I
A--SNQPEFTRENVS
G
T
L
V
G
I
---W
T
P
E
-----
L
F
H---GVGV-K-
G
F
H
----------
V
H
F
ISD--D---LT-FGG
H
V
M
D
Y
S-L--TQG
K
V
EI-G-K
V
D
Q
L
D
QCFPTQ
D
Q
-
E
F
L
E
ANF
D
L
Q
K
L
R
E
DIDLSE-------------------------------------------
23
HHSearch
98.36
43%
-91
* C5 *
1XV2
1
?
A:
[6-237]
----
N
V
L
Y
Q
H
G
T
L
G
T
L
M
A
G
L
L
-
E
G
T
A
T
I
N
------
E
L
-
L
E
H
G
N
----
L
G
I
A
-
T
L
-----
T
G
S
------------
D
G
E
V
I
F
L
D
G
---
K
--
A
Y
H
A
N
-
E
H
K
E
F
--
I
E
L
K
G
D
E
K
V
P
Y
A
-
S
I
T
N
F
K
A
S
K
T
F
P
L
Q
Q
-
L
S
Q
D
-------
D
V
F
A
Q
I
K
N
E
M
L
S
E
N
L
-
F
-
S
-
A
V
K
I
--
Y
G
------------
T
F
K
H
M
H
V
R
M
M
P
-
A
Q
Q
P
P-
Y
T
----
R
L
I
D
S
A
--
R
R
Q
P
E
E
K
R
Q
D
I
R
G
A
I
V
G
F
---
F
T
P
E
-----
L
F
H
---
G
V
G
S
-
A
-
G
F
H
----------
I
H
F
A
D
D
--
E
---
R
A
-
Y
G
G
H
V
L
D
F
E
-
V
--
D
D
V
V
V
E
I
-
Q
-
N
F
E
T
F
Q
Q
H
F
P
V
-
N
N
E
T
F
V
K
A
K
I
D
Y
K
D
V
A
E
E
I
R
E
A
E
-------------------------------------------
1
PsiBlast_PDB
97.97
41%
-94
- C5 -
1XV2
1
?
A:
[8-237]
------
L
Y
Q
H
G
T
L
G
T
L
M
A
G
L
L
-
E
G
T
A
T
I
N
------
E
L
-
L
E
H
G
N
----
L
G
I
A
-
T
L
-----
T
G
S
------------
D
G
E
V
I
F
L
D
G
---
K
--
A
Y
H
A
---
N
E
H
K
E
F
I
E
L
K
G
D
E
K
V
P
Y
A
-
S
I
T
N
F
K
A
S
K
T
F
P
L
Q
-
Q
L
S
Q
D
-------
D
V
F
A
Q
I
K
N
E
M
L
S
E
N
L
-
F
-
S
-
A
V
K
I
--
Y
G
------------
T
F
K
H
M
H
V
R
M
M
P
A
Q
Q
P
P
--
Y
T
----
R
L
I
D
S
A
--
R
R
Q
P
E
E
K
R
Q
D
I
R
G
A
I
V
G
F
---
F
T
P
E
-----
L
F
H
---
G
V
G
S
-
A
-
G
F
H
----------
I
H
F
A
D
D
--
E
---
R
A
-
Y
G
G
H
V
L
D
F
E
-
V
--
D
D
V
V
V
E
I
-
Q
-
N
F
E
T
F
Q
Q
H
F
P
V
N
N
E
-
T
F
V
K
A
K
I
D
Y
K
D
V
A
E
E
I
R
E
A
E
-------------------------------------------
7
PsiBlast_PDB
90.85
34%
-101
- C5 -
4BT7
2
ALDC_BREBE
A:
[25-234]
------
L
F
Q
Y
S
T
I
N
A
L
M
L
G
Q
F
-
E
G
D
L
T
L
K
------
D
L
-
K
L
R
G
D
----
M
G
L
G
-
T
I
-----
N
D
L
------------
D
G
E
M
I
Q
M
G
T
---
K
--
F
Y
Q
I
---
D
S
T
G
K
L
S
E
L
P
E
S
V
K
T
P
F
A
-
V
T
T
H
F
E
P
K
E
K
T
T
L
T
N
V
Q
D
Y
N
-------
Q
L
T
K
M
L
E
E
K
F
E
N
K
N
V
-
F
-
Y
-
A
V
K
L
--
T
G
------------
T
F
K
M
V
K
A
R
T
V
P
-
K
Q
T
R
P-
Y
P
----
Q
L
T
E
V
T
--
K
K
Q
S
E
F
E
F
K
N
V
K
G
T
L
I
G
F
---
Y
T
P
N
-----
Y
A
A
---
A
L
N
V
-
P
-
G
F
H
----------
L
H
F
I
T
E
--
D
---
K
T
-
S
G
G
H
V
L
N
L
Q
-
F
--
D
N
A
N
L
E
I
-
S
-
P
I
H
E
F
D
V
Q
L
P
H
T
D
D
-
F
A
H
S
D
L
T
Q
V
T
T
S
Q
V
H
Q
A
E
S
E
-------------------------------------------
5
PsiBlast_PDB
90.65
34%
-101
- C5 -
4BT5
2
ALDC_BREBE
A:
[25-234]
------
L
F
Q
Y
S
T
I
N
A
L
M
L
G
Q
F
-
E
G
D
L
T
L
K
------
D
L
-
K
L
R
G
D
----
M
G
L
G
-
T
I
-----
N
D
L
------------
D
G
E
M
I
Q
M
G
T
---
K
--
F
Y
Q
I
---
D
S
T
G
K
L
S
E
L
P
E
S
V
K
T
P
F
A
-
V
T
T
H
F
E
P
K
E
K
T
T
L
T
N
V
Q
D
Y
N
-------
Q
L
T
K
M
L
E
E
K
F
E
N
K
N
V
-
F
-
Y
-
A
V
K
L
--
T
G
------------
T
F
K
M
V
K
A
R
T
V
P
-
K
Q
T
R
P-
Y
P
----
Q
L
T
E
V
T
--
K
K
Q
S
E
F
E
F
K
N
V
K
G
T
L
I
G
F
---
Y
T
P
N
-----
Y
A
A
---
A
L
N
V
-
P
-
G
F
H
----------
L
H
F
I
T
E
--
D
---
K
T
-
S
G
G
H
V
L
N
L
Q
-
F
--
D
N
A
N
L
E
I
-
S
-
P
I
H
E
F
D
V
Q
L
P
H
T
D
D
-
F
A
H
S
D
L
T
Q
V
T
T
S
Q
V
H
Q
A
E
S
E
-------------------------------------------
6
PsiBlast_PDB
90.15
34%
-100
- C5 -
4BT6
5
ALDC_BREBE
A:
[25-234]
------
L
F
Q
Y
S
T
I
N
A
L
M
L
G
Q
F
-
E
G
D
L
T
L
K
------
D
L
-
K
L
R
G
D
----
M
G
L
G
-
T
I
-----
N
D
L
------------
D
G
E
M
I
Q
M
G
T
---
K
--
F
Y
Q
I
---
D
S
T
G
K
L
S
E
L
P
E
S
V
K
T
P
F
A
-
V
T
T
H
F
E
P
K
E
K
T
T
L
T
N
V
Q
D
Y
N
-------
Q
L
T
K
M
L
E
E
K
F
E
N
K
N
V
-
F
-
Y
-
A
V
K
L
--
T
G
------------
T
F
K
M
V
K
A
R
T
V
P
-
K
Q
T
R
P-
Y
P
----
Q
L
T
E
V
T
--
K
K
Q
S
E
F
E
F
K
N
V
K
G
T
L
I
G
F
---
Y
T
P
N
-----
Y
A
A
---
A
L
N
V
-
P
-
G
F
H
----------
L
H
F
I
T
E
--
D
---
K
T
-
S
G
G
H
V
L
N
L
Q
-
F
--
D
N
A
N
L
E
I
-
S
-
P
I
H
E
F
D
V
Q
L
P
H
T
D
D
-
F
A
H
S
D
L
T
Q
V
T
T
S
Q
V
H
Q
A
E
S
E
-------------------------------------------
4
PsiBlast_PDB
90.05
34%
-102
- C5 -
4BT4
2
ALDC_BREBE
A:
[25-234]
------
L
F
Q
Y
S
T
I
N
A
L
M
L
G
Q
F
-
E
G
D
L
T
L
K
------
D
L
-
K
L
R
G
D
----
M
G
L
G
-
T
I
-----
N
D
L
------------
D
G
E
M
I
Q
M
G
T
---
K
--
F
Y
Q
I
---
D
S
T
G
K
L
S
E
L
P
E
S
V
K
T
P
F
A
-
V
T
T
H
F
E
P
K
E
K
T
T
L
T
N
V
Q
D
Y
N
-------
Q
L
T
K
M
L
E
E
K
F
E
N
K
N
V
-
F
-
Y
-
A
V
K
L
--
T
G
------------
T
F
K
M
V
K
A
R
T
V
P
-
K
Q
T
R
P-
Y
P
----
Q
L
T
E
V
T
--
K
K
Q
S
E
F
E
F
K
N
V
K
G
T
L
I
G
F
---
Y
T
P
N
-----
Y
A
A
---
A
L
N
V
-
P
-
G
F
H
----------
L
H
F
I
T
E
--
D
---
K
T
-
S
G
G
H
V
L
N
L
Q
-
F
--
D
N
A
N
L
E
I
-
S
-
P
I
H
E
F
D
V
Q
L
P
H
T
D
D
-
F
A
H
S
D
L
T
Q
V
T
T
S
Q
V
H
Q
A
E
S
E
-------------------------------------------
2
PsiBlast_PDB
89.72
34%
-101
- C5 -
4BT2
2
ALDC_BREBE
A:
[25-234]
------
L
F
Q
Y
S
T
I
N
A
L
M
L
G
Q
F
-
E
G
D
L
T
L
K
------
D
L
-
K
L
R
G
D
----
M
G
L
G
-
T
I
-----
N
D
L
------------
D
G
E
M
I
Q
M
G
T
---
K
--
F
Y
Q
I
---
D
S
T
G
K
L
S
E
L
P
E
S
V
K
T
P
F
A
-
V
T
T
H
F
E
P
K
E
K
T
T
L
T
N
V
Q
D
Y
N
-------
Q
L
T
K
M
L
E
E
K
F
E
N
K
N
V
-
F
-
Y
-
A
V
K
L
--
T
G
------------
T
F
K
M
V
K
A
R
T
V
P
-
K
Q
T
R
P-
Y
P
----
Q
L
T
E
V
T
--
K
K
Q
S
E
F
E
F
K
N
V
K
G
T
L
I
G
F
---
Y
T
P
N
-----
Y
A
A
---
A
L
N
V
-
P
-
G
F
H
----------
L
H
F
I
T
E
--
D
---
K
T
-
S
G
G
H
V
L
N
L
Q
-
F
--
D
N
A
N
L
E
I
-
S
-
P
I
H
E
F
D
V
Q
L
P
H
T
D
D
-
F
A
H
S
D
L
T
Q
V
T
T
S
Q
V
H
Q
A
E
S
E
-------------------------------------------
3
PsiBlast_PDB
89.46
34%
-100
- C5 -
4BT3
2
ALDC_BREBE
A:
[25-234]
------
L
F
Q
Y
S
T
I
N
A
L
M
L
G
Q
F
-
E
G
D
L
T
L
K
------
D
L
-
K
L
R
G
D
----
M
G
L
G
-
T
I
-----
N
D
L
------------
D
G
E
M
I
Q
M
G
T
---
K
--
F
Y
Q
I
---
D
S
T
G
K
L
S
E
L
P
E
S
V
K
T
P
F
A
-
V
T
T
H
F
E
P
K
E
K
T
T
L
T
N
V
Q
D
Y
N
-------
Q
L
T
K
M
L
E
E
K
F
E
N
K
N
V
-
F
-
Y
-
A
V
K
L
--
T
G
------------
T
F
K
M
V
K
A
R
T
V
P
-
K
Q
T
R
P-
Y
P
----
Q
L
T
E
V
T
--
K
K
Q
S
E
F
E
F
K
N
V
K
G
T
L
I
G
F
---
Y
T
P
N
-----
Y
A
A
---
A
L
N
V
-
P
-
G
F
H
----------
L
H
F
I
T
E
--
D
---
K
T
-
S
G
G
H
V
L
N
L
Q
-
F
--
D
N
A
N
L
E
I
-
S
-
P
I
H
E
F
D
V
Q
L
P
H
T
D
D
-
F
A
H
S
D
L
T
Q
V
T
T
S
Q
V
H
Q
A
E
S
E
-------------------------------------------
27
HHSearch
47.93
19%
-60
- C5 -
2HX0
1
?
A:
[28-127]
-------------------------------------------------------------------------------------------------------------------------------------
G
Q
-------
E
V
F
S
Q
L
H
A
F
V
Q
Q
N
Q
L
-
R
-
A
A
W
I
A
G
C
-
T
G
------------
S
L
T
D
V
A
L
R
Y
A
G
-
Q
E
A
T
T
S
L
T
----
G
-----------
T
F
E
V
I
S
L
N
G
T
L
-------
E
L
T
------------------
G
E
H
----------
L
H
L
A
V
S
D
P
Y
G--
V
M
-
L
G
G
H
M
M
P
G
C
T
V
R-
T
T
L
E
L
V
I
-
G
-
E
L
P
A
L
T
F
S
R
Q
P
C
A
I
-
S
G
Y
D
E
L
H
I
S
S
R
L
---------------------------------------------------
26
HHSearch
45.49
22%
-21
- C5 -
2P6Y
1
?
A:
[12-116]
-------------------------------------------------------------------------------------------------------------------------------------
G
M
-------
D
L
K
Q
Q
I
V
Q
L
V
Q
Q
H
R
I
-
H
-
A
-
G
S
I
A
S
C
V
G
------------
C
L
S
T
L
H
I
R
L
A
D
-
S
-----
V
S
----
T
----
L
--
Q
V
S
A
P
F
E
I
L
S
L
S
G
T
L
T
-------
Y
-----------------
Q
-
H
C
H
----------
L
H
I
A
V
A
--
D
AQG
R
V
-
W
G
G
H
L
L
E
G
N
-
L
IN-
T
A
E
L
M
I
-
H
-
H
Y
P
Q
H
H
F
T
R
E
F
D
P
N
-
T
G
Y
S
E
L
V
V
S
A
A
----------------------------------------------------
41
Fugue
44.87
16%
-45
- C1 -
4AV9
3
HSV2_KLULA
A:
[14-338]
-
S
N
P
I
V
D
Y
E
F
N
Q
D
Q
S
C
L
I
V
S
T
-
P
K
S
F
D
I
Y
NVHPLK
R
I
-
M
S
Q
E
M
----
P
D
A
G
-
T
I
-----
R
M
L
HRTN
Y
I
A
F
V
S
TK
K
E
L
L
H
I
W
D
D
VKK
Q
--
D
I
T
R
V
K
L
D
A
A
V
K
D
L
F
L
S
R
E
F
I
V
V
S
Q
-
G
D
V
I
S
I
F
K
F
G
N
P
W
N
K
I
T
E
D
I
-------
K
F
G
G
--
V
C
E
F
A
N
G
L
L
-
V
-
Y
-
S
N
E
F
--
N
--------------
L
G
Q
I
H
V
T
R
L
Q
-
T
D
A
E
--
Q
V
VGK
G
V
L
V
K
A
H
--
A
N
P
V
K
M
V
R
L
N
R
K
G
D
M
V
A
T
---
C
S
Q
D
GT
L
I
R
V
F
Q
TDN
G
V
L
V
-
R
-
E
F
R
RGL
D
R
T
S
I
I
D
M
R
W
S
P
D
--
G
---
S
K
-
L
A
V
V
S
D
K
W
T
-
L
--
H
V
F
E
V
F
N
-
D
-
A
E
N
K
R
H
V
L
K
D
W
I
N
S
-
E
W
S
I
C
N
F
K
L
K
V
S
K
G
S
N
D
C
K
I
A
W
ISDT
G
L
V
I
V
W
PNRR
L
A
D
T
F
K
L
N
Y
NDDEH
V
W
W
L
Q
L
N
Q
R
N
E
IP
25
HHSearch
44.19
11%
-46
- C5 -
3HTN
6
?
A:
[25-128]
-------------------------------------------------------------------------------------------------------------------------------------
H
T
-------
E
I
V
K
A
L
N
A
F
C
K
E
K
G
I
L
S
-
G
-
S
I
N
G
--
I
G
------------
A
I
G
E
L
T
L
R
F
F
N
-
P
K
T
K
A
-
Y
D
----
D
K
------
T
F
R
E
Q
M
E
I
S
N
L
T
G
N
I
S
-------
S
M
-------
N
-----
E
Q
-
V
-
Y
L
H
----------
L
H
I
T
V
G
R
S
D
Y--
S
A
-
L
A
G
H
L
L
S
A
I
-
Q
N-
G
A
G
E
F
V
V
-
E
-
D
Y
S
E
R
I
S
R
T
Y
N
P
D
L
-
G
L
N
I
Y
D
F
E
R
------------------------------------------------------
28
HHSearch
44.03
13%
-45
- C5 -
2DT4
1
?
A:
[20-122]
--------------------------------------------------------------------------------------------------------------------------------------
E
-------
E
L
L
T
Y
I
K
N
F
C
K
K
E
G
I
-
E
T
A
-
I
I
N
G
--
I
G
------------
T
L
K
N
P
K
I
G
Y
F
L
-
E
E
K
K
E-
Y
K
----
V
I
P
------
L
K
G
S
Y
E
L
I
S
L
I
G
N
V
-------
S
L
K
-------
D
-----
G
E
-
P
-
F
V
H
----------
A
H
V
S
L
G
--
N
EEG
I
V
-
F
G
G
H
L
V
E
G
E
-
V
--
F
V
A
E
I
F
L
-
Q
-
E
L
K
G
E
K
I
E
R
K
P
T
K
Y
-
G
L
A
L
W
E
E
L
K
L
-----------------------------------------------------
39
Fugue
41.00
23%
-12
- C5 -
1JYO
-
SICP_SALTY
A:
[1-130]
-------------------------------------------------------------------------------------------------------------------------
L
Q
A
H
Q
D
I
I
A
N
I
G
E
K
L
GLP
L
T
F
D
D
N
N
Q
C
L
L
L
L
D
S
-
D
I
-
F
-
T
-
S
I
E
A
--
K
D
------------
D
I
W
L
L
N
G
M
I
I
P
-
L
S
P
V
CG
D
S
----
I
W
R
Q
I
M
--
V
I
N
G
E
L
A
A
N
N
-
E
G
T
L
A
Y
I
DAA
E
T
L
L
-----
L
I
H
---
A
I
T
D
-
L
-
T
N
T
----------
Y
H
I
I
S
Q
--
L
---
E
S
-
F
V
N
Q
Q
E
A
L
K
-
N
--
I
L
Q
E
Y
A
K
-
V
-------------------------------------------------------------------------------
34
Fugue
40.83
16%
-17
- C5 -
2XQH
4
?
A:
[23-280]
-
S
D
A
K
A
S
G
E
F
S
V
A
V
G
N
G
A
R
A
T
E
K
A
S
T
A
V
G
------
S
W
A
A
A
D
G
K
Q
S
T
A
L
G
V
G
-
T
Y
AYANA
S
T
A
------------
L
G
S
V
A
F
V
D
N
---
T
--
A
T
Y
G
T
A
A
G
N
R
A
K
V
D
K
D
A
T
E
G
T
A
L
G
A
K
A
T
V
T
N
K
N
S
V
A
L
G
A
N
S
V
T
T
R
D
-------
N
E
V
Y
I
G
Y
K
T
G
T
E
S
D
K
-
T
-
Y
-
G
T
R
V
--
L
G
GLSDGTRNSDAA
T
V
G
Q
L
N
R
K
V
G
G
-
V
Y
D
D
--
V
K
----
A
R
I
T
V
E
--
S
E
K
Q
K
K
Y
T
D
Q
K
T
S
E
V
N
E
K
---
V
E
A
R
-----
T
T
V
---
G
V
D
S
-
D
-
G
K
L
----------
T
R
A
-------------
E
G
A
T
K
T
I
A
-
V
--
N
D
G
L
V
A
L
S
G
-
R
T
D
R
I
D
Y
A
V
G
A
I
D
G
-
R
V
T
R
N
T
Q
S
I
E
K
N
S
K
A
I
A
A
N
T
RT-----------------------------------------
15
PsiBlast_PDB
38.40
24%
-42
- C5 -
4NHY
-
OGFD1_HUMAN
A:
[279-363]
--------------------------------------------------------------------------------------------------------
I
P
Q
D
H
E
I
L
Y
D
-
W
I
N
P
T
Y
L
D
M
D
Y
Q
V
Q
I
Q
E
E
F
E
-------
E
S
S
E
I
L
L
K
E
F
L
K
P
E
K
-
F
----
T
K
V
--
C
E
------------
A
L
E
H
G
H
V
E
W
S
S
-
R
G
P
P
--
N
K
----
R
F
Y
E
K
A
EE
S
K
L
P
E
I
L
K
E
C
M
K
L
F
R
S
E
A
---
L
F
L
L
-----
L
S
N
---
F
T
G
L
-
K
-
L
H
F
----------
L
A
P
S
S
S
--
V
---
P
M
-
C
Q
G
E
L
R
H
W
K
-
T
--
G
H
Y
T
L
I
H
-
D
-
H
S
K
A
E
F
A
L
D
L
I
L
Y
C
-
G
C
E
G
W
E
P
E
Y
G
G
F
T
S
Y
I
A
K
G
E
-------------------------------------------
40
Fugue
38.24
12%
-13
- C2 -
2BH0
-
YOAJ_BACSU
A:
[2-208]
--------
A
Y
D
D
L
H
E
G
Y
A
T
Y
T
-
G
S
G
Y
S
G
G
------
A
F
--
L
L
D
P
----
I
P
S
D
M
E
I
-----
T
A
I
------------
N
P
A
D
L
N
Y
G
G
---
V
--
K
A
A
L
A
G
S
--
Y
L
E
V
E
G
P
K
G
K
T
T
V
Y
V
T
-
D
L
Y
P
E
G
A
R
G
A
L
D
L
S
-------------------------
P
N
A
-
F
-
R
-
K
I
G
N
M-
K
D
------------
G
K
I
N
I
K
W
R
V
V
K
-
A
P
I
T
--
G
N
----
F
T
Y
R
I
K
--
E
G
S
------
S
R
W
W
A
A
I
Q
V
---
R
---------
N
H
---
K
Y
P
V
M
K
M
E
Y
E
----------
K
D
G
K
W
I
--
N
M
--
E
K
M
D
Y
N
H
F
V
S
T
N
-
L
--
G
T
G
S
L
K
V
-
R
M
T
D
I
R
G
K
V
V
K
D
T
I
P
K
-
L
P
E
S
G
T
S
K
A
Y
T
V
P
G
H
V
Q
F
P
E
-------------------------------------------
14
PsiBlast_PDB
37.34
24%
-42
- C5 -
4NHX
-
OGFD1_HUMAN
A:
[279-363]
--------------------------------------------------------------------------------------------------------
I
P
Q
D
H
E
I
L
Y
D
-
W
I
N
P
T
Y
L
D
M
D
Y
Q
V
Q
I
Q
E
E
F
E
-------
E
S
S
E
I
L
L
K
E
F
L
K
P
E
K
-
F
----
T
K
V
--
C
E
------------
A
L
E
H
G
H
V
E
W
S
S
-
R
G
P
P
--
N
K
----
R
F
Y
E
K
A
EE
S
K
L
P
E
I
L
K
E
C
M
K
L
F
R
S
E
A
---
L
F
L
L
-----
L
S
N
---
F
T
G
L
-
K
-
L
H
F
----------
L
A
P
S
S
S
--
V
---
P
M
-
C
Q
G
E
L
R
H
W
K
-
T
--
G
H
Y
T
L
I
H
-
A
-
E
F
A
L
D
L
I
L
Y
C
G
C
E
G
-
W
E
P
E
Y
G
G
F
T
S
Y
I
A
K
G
E
D
E
E
L
-------------------------------------------
21
PsiBlast_CBE
35.98
35%
-42
- C5 -
2PUI
3
MTNK_BACSU
B:
[204-262]
-----
K
L
W
N
N
D
S
V
K
I
E
A
A
K
L
K
-
K
S
F
L
T
S
A
------
E
T
-
L
I
H
G
D
----
L
H
T
G
-
S
I
-----
F
A
S
------------
E
H
E
T
K
V
I
D
P
---
E
FA
F
Y
G
P
I
G
F
D
V
G
Q
F
I
A
N
L
F
L
N
A
L
S
R
D
G
-
A
D
R
E
P
L
Y
E
H
V
N
Q
V
W
E
T
F
E
E
T
-------
F
S
E
A
W
Q
K
D
S
L
D
V
Y
A
N
-
I
-
D
-
G
Y
L
T
--
D
T
------------
L
S
H
I
F
E
E
A
I
G
F
-
A
G
C
E
--
L
I
----
R
R
T
I
G
L
--
A
H
V
A
D
L
D
T
I
V
P
F
D
K
R
I
G
R
---
K
R
L
A
-----
L
E
T
---
G
T
A
F
-
I
-
E
K
R
----------
S
E
F
K
T
I
--
T
---
D
V
-
I
E
L
F
K
L
L
V
K
--------------------------------------------------------------------------------------------
13
PsiBlast_PDB
35.67
35%
-42
- C5 -
2PUP
3
MTNK_BACSU
A:
[204-262]
-----
K
L
W
N
N
D
S
V
K
I
E
A
A
K
L
K
-
K
S
F
L
T
S
A
------
E
T
-
L
I
H
G
D
----
L
H
T
G
-
S
I
-----
F
A
S
------------
E
H
E
T
K
V
I
D
P
---
E
FA
F
Y
G
P
I
G
F
D
V
G
Q
F
I
A
N
L
F
L
N
A
L
S
R
D
G
-
A
D
R
E
P
L
Y
E
H
V
N
Q
V
W
E
T
F
E
E
T
-------
F
S
E
A
W
Q
K
D
S
L
D
V
Y
A
N
-
I
-
D
-
G
Y
L
T
--
D
T
------------
L
S
H
I
F
E
E
A
I
G
F
-
A
G
C
E
--
L
I
----
R
R
T
I
G
L
--
A
H
V
A
D
L
D
T
I
V
P
F
D
K
R
I
G
R
---
K
R
L
A
-----
L
E
T
---
G
T
A
F
-
I
-
E
K
R
----------
S
E
F
K
T
I
--
T
---
D
V
-
I
E
L
F
K
L
L
V
K
--------------------------------------------------------------------------------------------