@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1420: (2015-12-07 )
MKKGQVNDTKQSYSLRKYKFGLASVILGPFIMVTSPVFADQTTSVQVNNQTGTSVDANNSSNETSASSVITSNNDSVQASDKVVNSQNTATKDITTPLVETKPMVEKTLPEQGNYVYSKETEVKNTPSKSAPVAFYAKKGDKVFYDQVFNKDNVKWISYKSFCGVRRYAAIESLDPSGGSETKAPTPVTNSGSNNQEKIATQGNYTFSHKVEVKNEAKVASPTQFTLDKGDRIFYDQILTIEGNQWLSYKSFNGVRRFVLLGKASSVEKTEDKEKVSPQPQARITKTGRLTISNETTTGFDILITNIKDDNGIAAVKVPVWTEQGGQDDIKWYTAVTTGDGNYKVAVSFADHKNEKGLYNIHLYYQEASGTLVGVTGTKVTVAGTNSSQEPIENGLAKTGVYNIIGSTEVKNEAKISSQTQFTLEKGDKINYDQVLTADGYQWISYKSYSGVRRYIPVKKLTTSSEKAKDEATKPTSYPNLPKTGTYTFTKTVDVKSQPKVSSPVEFNFQKGEKIHYDQVLVVDGHQWISYKSYSGIRRYIEI
Atome Classification :
(20 SA)
-----------------.........10........20........30...---..---...40---........50........60........70........80........90......----..100.......110..---------....----------.120..-.....130......-------------.140......---------.150....------------...--160....-------...170.......180.......190.......200-.......210..-.....220..-.....230.......240.......250.......260.......270.......---280.......290.......300--....----....310.......320...---...-.330.----......340.--......350.......360---.-----.....-...370..--.....380.......390.....------....400.......410....--...420.......430..--------------...---..440.......450.......460.-----......470.......480-........490....-..---.500-...------------....510..-----.....520.---...--...530.......540.------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------MKKGQVND
T
K
QSYS
L
R
K
Y
K
F
G
L
A
S
V
I
LGP
F
I
M
V
T---SP---VFADQ---T
T
S
V
Q
VNNQTG
T
S
VDANNSSNETSA
S
S
V
I
TSNNDSVQASDKVVNSQNTATKDITTP----LVETK
P
M
V
E
KTLPEQG
N
---------
Y
V
Y
S----------KETEVK-NTPSKSA
P
V
A
F
Y
AK-------------KG
D
K
V
F
Y
D
Q
V---------FNKDN
V
K
W
------------
I
S
Y
--
K
S
FCG
V
R
-------
R
Y
A
A
IESLDPSGGSETKAPTPVTNSGSN
N
Q
E
K
I
A
TQ-GN
Y
T
F
S
H
K
V
E
V
K-NEAKVASP
T
Q
-
F
TLDKG
D
R
I
F
Y
D
Q
I
L
T
IEGN
Q
W
L
S
YKSFNG
V
R
R
F
V
L
LGKASSVEKTEDKEKVSPQ---PQ
A
R
I
T
KT
G
R
L
T
ISNETTT
G
F
D
---
I
L
I
T
----NIKDDN
G
I
A
A
V
K
V
P
V
W
TEQG---GQD-
D
I
K
W
Y
----
T
A
V
T
TGDG
N
Y
--
K
V
A
V
S
FADHKNEKG
L
Y
N
-----
I
-----
H
L
Y
Y
Q-EAS
G
T
L
V
G
--VTG
T
K
V
T
V
AGTNSSQ
E
--
P
I
E
N
G
------
L
A
KTG
V
Y
N
IIGSTEVKNEAKI--SSQ
T
Q
F
T
LEKGDKINYD
Q
--------------
V
LT---ADG
Y
Q
W
I
S
YKSYSG
V
R
R
Y
I
PVKKLTT-----SSEKAKDEATKPTSYPNL--PKTG
T
Y
T
F
T
K
T
VDVK-SQ---PKVS-S
P
V
------------
E
F
NFQKG
E
K
-----
I
HY
D
Q
V
L
V
V---DGH--Q
W
I
S
YK
S
Y
S
G
I
R
R
Y
IEI------------------
27
Fugue
77.13
17%
17
* C7 *
2ZB6
2
HEMA_MEASE
A:
[12-462]
----------------------
V
A
A
E
E
L
M
N
A
L
S
K
G
N
C
S
-----------------------
G
P
T
---
T
I
R
G
Q
F
S
N
M
S
L
S
L
L
D
L
Y
L
G
R
G
-
Y
N
V
S
S
I
V
T
M
T
S
Q
G
M
Y
G
G
T
Y
L
V
E
K
P
N
L
-
S
Q
L
S
M
Y
R
----
V
F
E
V
G
V
I
R
N
---
P
G
L
G
A
---------
P
V
F
H
----------
M
T
N
Y
L
E
-
Q
P
V
S
N
D
L
S
N
C
M
V
A
L
--------------
G
E
L
K
L
A
A
L
C
---------
H
G
E
D
S
I
T
I
------------
P
Y
Q
--
G
S
G
K
G
V
S
-------
F
Q
L
V
K
L
G
V
W
K
S
-------
P
T
D
M
Q
S
W
V
P
L
S
T
D
D
P
V
I
D
-
R
L
Y
L
S
S
H
R
G
V
I
A
D
N
Q
A
K
W
A
V
P
T
T
-
R
T
D
D
K
L
R
M
E
T
C
F
Q
Q
A
C
-----------------------
K
G
K
I
Q
A
L
C
E
N
P
E
W
A
P
L
---
K
D
N
R
I
P
S
Y
G
V
L
S
V
D
L
S
L
T
V
E
L
K
---
I
K
I
A
----
S
G
F
G
---------
P
L
I
T
H
G
S
---
G
M
D
-
L
Y
K
---------
S
N
H
N
N
V
Y
--
W
L
T
I
P
P
M
K
N
L
-------------------------
A
L
G
V
I
N
T
--
L
E
W
I
P
R
F
K
V
S
P
Y
L
F
T
V
--
P
I
K
E
A
------
G
G
D
C
H
A
P
T
Y
L
-
P
A
E
V
D
G
D
V
K
L
--
S
S
N
L
-------------
V
--------------
I
L
P
---
G
Q
D
L
Q
Y
V
L
A
T
Y
D
T
S
R
V
E
H
A
V
V
Y
Y
V
Y
S
-----
P
S
-------------------
R
S
F
S
Y
F
Y
P
F
R
L
P
I
K
-
G
V
---
P
-
I
E
-
L
Q
V
------------
E
C
-
F
T
W
D
Q
K
-----
L
W
C
R
H
F
C
V
L
A
D
S
E
S
G
--
G
H
I
T
H
S
G
M
V
G
M
G
V
S
C
T
-------------------
31
Fugue
75.05
18%
14
- C7 -
1Q9J
-
PAPA5_MYCTU
A:
[1-418]
-----------------
M
F
P
G
S
V
I
R
K
---
L
S
H
S
E
E
V
F
A
Q
Y
E
V
F
T
S
M
T
I
Q
L
R
---
G
V
---
I
------------
D
V
D
A
L
S
D
A
F
D
A
L
L
E
T
H
P
V
L
A
S
H
L
E
Q
S
S
D
G
G
W
N
L
V
A
D
D
L
L
H
S
G
I
C
V
I
D
A
E
L
R
----
L
D
Q
S
V
S
L
L
H
L
Q
L
I
L
R
E
G
-----------------------------------
G
A
E
L
T
L
Y
L
H
----------------
H
C
M
A
D
G
H
---------
H
G
A
V
L
V
D
E
------------
L
F
S
--------
R
-------
Y
T
D
A
V
T
T
G
D
P
--
G
P
I
T
P
Q
P
T
P
L
------
S
M
E
A
V
L
A
Q
-
R
G
I
R
K
A
E
R
F
M
S
V
-
M
Y
A
Y
P
G
L
P
Q
A
-
V
P
V
T
R
L
---------------
W
L
S
K
Q
Q
T
S
D
L
M
A
F
G
-----------------------------
R
E
H
R
L
--
S
L
N
A
V
V
A
A
A
---
I
L
L
T
----
E
W
Q
L
R
N
--------------------------------------
T
P
--
H
V
P
I
P
Y
V
Y
P
V
D
L
R
F
V
L
A
-----
P
-----
P
V
A
P
T
-
E
A
T
-
N
L
L
G
--
A
A
S
Y
L
A
E
I
G
---------------------
P
N
T
D
I
V
D
L
A
S
D
I
V
A
T
L
R
A
D
L
--
A
N
G
-----------------------------
V
I
Q
---
Q
S
G
L
H
--
F
G
T
A
F
E
G
T
P
P
G
L
P
P
L
V
F
C
T
-----
D
----------
A
T
S
F
P
T
M
--
R
T
P
P
G
L
---
E
I
E
D
I
K
-
G
Q
---
F
Y
C
S
-
I
S
V
------------
P
L
D
L
Y
S
C
A
V
-----
Y
A
G
Q
L
I
I
E
H
---
H
G
H
--
I
A
E
P
G
K
S
L
E
A
I
R
S
L
L
C
T
V
P
S
EYG------------
24
Fugue
73.60
17%
21
- C5 -
3WOL
10
DAPB2_PSEMX
A:
[1-696]
GEGMWVPQQLPEI
A
G
P
L
K
K
A
G
L
K
L
S
P
Q
Q
I
S
D
L
T
G
D
P
M
G
A
V
V
A
L
G
G
C
T
A
S
F
V
---
S
P
NG
L
V
V
T
N
H
HCA
Y
G
A
I
Q
L
N
S
T
A
E
N
N
L
I
K
N
G
F
N
A
P
T
T
A
D
E
V
S
A
G
P
N
A
R
V
F
V
L
D
E
I
T
D
V
T
K
D
A
K
A
A
I
A
A
A
GDD
A
L
A
R
T
K
A
L
E
A
F
E
K
K
L
I
A
D
C
E
AEAG
F
R
C
R
L
Y
S
F
SGGN
T
Y
R
L
F
K
N
L
E
I
K
-
D
V
R
L
A
Y
A
P
P
G
S
V
G
K
FGGDIDNWMWPRH
T
G
D
F
A
F
Y
R
A
Y
V
G
KDG
K
P
A
A
F
S
K
D
N
V
P
Y
Q
P
K
H
W
L
K
F
A
D
Q
P
L
G
A
--
G
D
F
V
M
V
A
G
Y
P
G
S
TN
R
Y
A
L
A
A
E
F
D
N
T
A
Q
W
T
Y
P
T
I
A
R
H
Y
K
N
Q
I
A
M
V
E
A
A
G
K
Q
N
A
D
I
Q
V
K
Y
A
A
T
M
A
-
G
W
N
N
T
S
K
N
Y
D
-
G
Q
L
E
G
F
K
R
I
D
A
A
G
Q
K
L
R
E
E
A
A
V
L
G
W
L
K
G
Q
G
A
K
G
Q
P
A
L
D
A
H
A
K
L
L
D
L
L
E
Q
S
K
A
T
R
D
---
R
D
L
T
L
A
L
F
N
N
T
A
M
L
G
S
A
T
Q
L
Y
R
---
L
S
I
E
R
E
K
P
N
A
E
R
E
S
G
Y
Q
E
R
D
L
P
A
I
E
G
G
L
---
K
Q
L
-
E
R
R
Y
V
----
A
A
M
D
R
Q
L
Q
E
Y
W
L
N
E
Y
I
K
L
P
A
D
Q
R
V
A
A
V
D
A
-----
W
L
GGND
A
A
A
V
K
-
R
A
L
D
R
L
A
G
TK
L
G
S
T
E
E
R
L
K
W
F
A
A
D
R
K
--
A
F
E
A
S
ND
P
A
I
Q
Y
A
V
A
V
M
P
T
L
L
K
L
E
Q
E
R
K
T
R
A
G
--
E
N
L
A
A
R
P
V
Y
L
Q
A
L
A
D
Y
K
K
S
Q
G
E
F
V
Y
P
DANL
S
L
R
I
T
F
G
N
V
M
G
Y
A
P
K
D
G
M
E
Y
T
P
F
T
T
L
E
G
V
V
A
K
E
T
GQDPF
D
S
P
K
A
L
L
D
A
V
A
A
K
R
Y
G
G
L
ED
K
R
I
G
S
V
P
V
N
Y
L
S
D
L
D
-
I
T
---
G
G
N
S
G
S
P
V
L
D
AHGKLV
G
L
A
F
D
G
N
W
E
S
V
S
S
NWVFD
P
K
M
T
R
M
I
A
V
---
D
G
R
Y
L
R
W
I
M
Q
E
V
Y
P
A
P
Q
L
L
K
E
M
NV----------------
26
Fugue
70.78
17%
10
- C8 -
1ZY7
2
RED1_HUMAN
A:
[8-402]
-----------------
S
R
Q
P
I
P
S
E
G
L
Q
L
H
L
P
Q
V
L
A
D
A
V
S
R
L
V
L
G
K
F
G
D
L
T
D
NF
S
S
---
P
H
A
R
R
---
K
V
L
A
G
V
V
M
T
T
G
T
D
V
K
D
---------
A
K
V
I
S
V
S
T
G
T
K
C
I
N
G
E
Y
M
S
D
R
G
L
A
L
N
D
C
H
A
E
----
I
I
S
R
R
S
L
L
R
F
L
Y
T
Q
L
E
L
---------
Y
L
N
N
----------
K
D
D
Q
K
R
-
S
I
F
Q
K
S
E
R
G
G
F
R
L
K
-----------------------------------
E
N
V
Q
F
------------
H
L
Y
I
S
T
S
P
C
G
D
A
-------
R
I
-----
F
K
A
R
G
Q
L
R
T
K
I
E
S
G
--------------
E
-
G
T
I
P
V
R
S
N
A
S
I
Q
-
T
W
D
G
V
L
Q
G
E
R
L
L
T
M
S
C
S
D
K
I
A
R
W
N
V
V
G
I
Q
G
S
L
L
S
I
F
V
E
P
I
Y
F
S
S
I
I
L
------------------------------
G
S
L
Y
H
G
D
H
L
S
R
A
M
Y
---
Q
R
I
S
----
N
I
E
D
L
P
P
L
Y
T
L
N
K
P
L
L
S
G
I
S
---
N
A
E
----------------------------
A
R
Q
P
G
K
A
P
N
F
S
-----
V
-----
N
W
T
V
G
-
D
S
A
I
E
V
I
N
--
A
T
-
T
G
K
D
E
L
G
R
A
S
R
---------------
L
C
K
H
A
L
Y
C
R
W
M
R
V
H
G
K
V
P
S
H
L
LR
S
K
I
T
K
P
N
V
Y
H
E
S
K
L
A
A
K
E
--------------
Y
Q
A
---
A
K
A
R
L
F
T
A
F
I
K
-
A
G
L
G
A
W
V
E
---------------------
K
P
T
E
Q
D
Q
F
--
S
L
T
--------------------------------------------------------------------------------------------------------
29
Fugue
61.72
17%
20
- C3 -
1OKE
4
POLG_DEN2P
A:
[1-394]
-----------------
M
R
C
--
I
G
I
S
N
R
D
F
V
E
G
V
S
G
G
S
W
V
D
I
V
L
E
H
G
S
C
V
T
---
T
M
---
A
K
N
K
P
---
T
L
D
F
E
L
I
K
T
E
A
K
Q
------------------------------------------
P
----
A
T
L
R
K
Y
C
I
E
A
K
L
T
---------------------------
N
T
T
T
E
S
-
R
C
P
T
Q
G
E
P
T
L
N
E
E
Q
-------------
D
K
R
F
V
C
K
H
S
M
---------
V
D
R
G
------------------
W
--
G
N
G
C
G
L
-----------------------------------
F
G
K
G
G
I
V
T
C
-
A
M
F
T
C
K
K
N
M
E
G
K
-
I
V
-------------
Q
P
E
N
L
E
Y
T
V
V
I
T
P
----------
H
S
G
E
E
H
A
V
----
G
N
D
T
G
K
H
G
K
E
V
K
I
T
P
Q
S
S
I
T
E
A
E
L
T
G
Y
G
T
V
T
M
E
C
S
P
R
T
G
L
D
FNE
M
V
L
L
----
Q
M
K
D
-------
K
A
W
L
V
H
R
Q
W
---
F
L
D
L
P
L
P
W
L
----
P
G
A
D
T
Q
G
S
N
W
--
I
Q
K
E
T
L
V
T
F
K
N
P
H
A
---------------------------------
K
K
Q
D
V
V
V
L
G
S
Q
E
G
--
A
M
H
T
A
------
L
T
--------
G
A
T
E
I
Q
M
---------
S
S
G
N
L
L
F
T
G
H
L
K
C
R
L
--------------
R
M
D
---
K
L
Q
L
K
G
M
S
Y
S
M
C
T
G
-----
K
F
K
V
V
K
E
-----
I
A
E
T
Q
H
G
T
I
V
I
R
V
Q
Y
E
G
D
--
G
S
P
C
K
I
P
F
E
I
M
-
D
L
E
-
K
R
---
H
V
L
G
-
R
L
I
------------
T
V
N
P
I
V
T
E
K
-----
D
S
P
V
N
I
E
A
E
P
P
-
F
G
D
--
S
Y
I
I
I
G
V
E
P
G
Q
L
K
L
N
W
F
K
K----------------
13
HHSearch
58.92
29%
-4
- C10 -
1R77
-
ALE1_STACP
A:
[279-344]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
K
--
S
E
S
A
S
F
T
A
N
T
D
I
I
T
R
L
T
G
---
P
F
R
S
-
M
P
Q
------------
S
G
V
L
R
K
G
L
T
-----
I
K
Y
D
E
V
M
K
Q
---
D
G
H
--
V
W
V
G
Y
N
T
N
S
G
K
R
V
Y
L
P
V
------------------
23
Fugue
58.26
33%
22
* C10 *
1R77
-
ALE1_STACP
A:
[264-362]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
D
K
V
K
L
Y
K
T
N
K
Y
G
T
L
--
Y
K
S
E
S
A
S
F
T
A
N
T
D
I
I
-
T
R
L
TG
P
F
R
S
-
M
P
Q
------------
S
G
V
L
R
K
G
L
T
-----
I
K
Y
D
E
V
M
K
Q
---
D
G
H
--
V
W
V
G
Y
N
T
N
S
G
K
R
V
Y
L
P
V
R
TWNESTGELGPLWGTIK
11
PsiBlast_CBE
57.95
34%
14
- C10 -
4LXC
1
LSTP_STASI
C:
[157-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
N
K
Y
G
T
L
--
Y
K
S
E
S
A
S
F
T
P
N
T
D
I
I
-
T
R
T
TG
P
F
R
S
-
M
P
Q
------------
S
G
V
L
K
A
G
Q
T
-----
I
H
Y
D
E
V
M
K
Q
---
D
G
H
--
V
W
V
G
Y
T
G
N
S
G
Q
R
I
Y
L
P
V
------------------
12
PsiBlast_CBE
56.30
34%
10
- C10 -
4LXC
2
LSTP_STASI
B:
[157-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
N
K
Y
G
T
L
--
Y
K
S
E
S
A
S
F
T
P
N
T
D
I
I
-
T
R
T
TG
P
F
R
S
-
M
P
Q
------------
S
G
V
L
K
A
G
Q
T
-----
I
H
Y
D
E
V
M
K
Q
---
D
G
H
--
V
W
V
G
Y
T
G
N
S
G
Q
R
I
Y
L
P
V
------------------
10
PsiBlast_CBE
54.80
34%
14
- C10 -
4LXC
1
D:
[157-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
N
K
Y
G
T
L
--
Y
K
S
E
S
A
S
F
T
P
N
T
D
I
I
-
T
R
TTG
P
F
R
S
-
M
P
Q
------------
S
G
V
L
K
A
G
Q
T
-----
I
H
Y
D
E
V
M
K
Q
---
D
G
H
--
V
W
V
G
Y
T
G
N
S
G
Q
R
I
Y
L
P
V
------------------
1
PsiBlast_PDB
54.66
34%
11
- C10 -
4LXC
1
LSTP_STASI
A:
[157-229]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
N
K
Y
G
T
L
--
Y
K
S
E
S
A
S
F
T
P
N
T
D
I
I
-
T
R
T
TG
P
F
R
S
-
M
P
Q
------------
S
G
V
L
K
A
G
Q
T
-----
I
H
Y
D
E
V
M
K
Q
---
D
G
H
--
V
W
V
G
Y
T
G
N
S
G
Q
R
I
Y
L
P
V
------------------
15
HHSearch
53.79
22%
37
- C10 -
1R77
-
ALE1_STACP
A:
[279-348]
----------------------------------------------------------------------------------------------------------------------------------------
L
Y
K
S
E
S
A
S
---------
F
T
A
N
----------
T
D
I
I
T
R
L
T
G
P
F
R
S
M
P
Q
S
G
V
L
R
-------------
K
G
L
T
I
K
Y
D
E
V
---------
M
K
Q
D
G
H
V
W
------------
V
G
Y
--
N
T
N
S
G
K
R
-------
V
Y
L
P
V
R
T
W
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
53.18
34%
9
- C10 -
1R77
-
ALE1_STACP
A:
[276-344]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
T
L
--
Y
K
S
E
S
A
S
F
T
A
N
T
D
I
I
-
T
R
L
TG
P
F
R
S
-
M
P
Q
------------
S
G
V
L
R
K
G
L
T
-----
I
K
Y
D
E
V
M
K
Q
---
D
G
H
--
V
W
V
G
Y
N
T
N
S
G
K
R
V
Y
L
P
V
------------------
30
Fugue
51.45
15%
26
- C8 -
4P5W
1
CMC2_HUMAN
A:
[31-394]
-----------------------
T
K
R
A
D
P
A
E
L
R
T
I
F
L
K
Y
A
S
I
E
K
N
G
E
F
F
M
S
---
P
N
---
D
F
V
-----
T
R
Y
L
N
I
F
S
Q
P
-------
N
P
K
T
V
E
L
L
S
G
V
V
D
Q
T
K
D
G
L
I
S
F
Q
E
F
V
A
F
E
S
V
L
C
A
P
D
---------
A
L
F
M
V
A
F
Q
L
F
D
K
A
G
K
---------
G
E
V
T
----------
F
E
-
D
V
K
-
Q
V
F
G
Q
T
T
I
H
Q
H
I
P
F
-------------
N
W
D
S
E
F
V
Q
L
H
---------
F
G
K
E
R
K
R
H
------------
L
T
Y
--
A
E
F
T
Q
F
L
-------
L
E
I
Q
L
E
H
A
K
Q
A
F
V
Q
R
D
N
A
R
T
G
R
V
T
-
A
I
D
F
R
D
I
M
V
T
I
-
R
P
H
V
L
T
P
F
V
E
E
C
-
L
V
A
A
A
G
G
T
T
S
-
H
Q
V
S
F
S
Y
F
N
G
F
N
S
L
L
N
N
M
E
L
I
R
K
I
Y
S
T
L
A
G
T
R
K
D
V
E
V
T
K
E
E
F
V
L
A
A
Q
K
F
G
Q
V
T
P
M
---
E
V
D
I
L
F
Q
L
A
D
L
Y
E
P
R
G
R
M
T
L
A
D
---
I
E
R
I
----
A
P
P
N
P
D
H
V
G
G
Y
K
L
A
V
A
T
F
A
G
---
I
E
N
-
K
F
G
L
Y
----
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
42.23
14%
-8
* C8 *
1DQG
1
MRC1_MOUSE
A:
[2-135]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
R
Q
---
F
L
I
Y
----
N
E
D
H
K
R
C
V
D
A
L
S
A
I
S
V
Q
T
A
T
CNP
E
A
E
-
S
Q
K
F
R
W
VSD
S
Q
I
M
S
V
A
F
K
L
--
C
L
G
V
P
S
K
T
D
W
A
S
V
T
L
Y
A
CDSKS
E
-----
Y
Q
K
W
E
-
C
K
N
D
T
L
F
G
--
I
K
G
T
E
L
Y
F
N
Y
G
N
R
Q
E
K
N
I
K
L
Y
K
G
------
S
G
L
W
S
R
W
K
V
Y
G
T
T
D
D
L
C
S
R
G
Y
--
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
39.90
23%
18
* C11 *
3BGY
2
MCE_MIMIV
A:
[92-196]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
I
---
G
E
F
-
I
T
K
F
S
----
K
A
S
S
N
D
I
S
R
Y
--
I
V
S
L
D
P
S
D
--------
D
-----
I
-----
E
I
V
Y
K
N
R
G
S
G
K
L
I
G
--
I
D
N
W
A
I
T
I
K
S
T
--
E
E
I
--
P
L
V
A
G
------
K
S
K
I
S
K
P
K
I
T
G
S
E
R
I
M
Y
R
Y
K
----
T
R
Y
S
F
T
I
N
K
N
S
R
I
D
I
T
D
--------------
V
K
S
---
S
P
I
I
W
K
L
M
T
V
P
S
N
Y
E
L
E
L
E
L
I
N
K
I
D
I
-----
N
T
L
E
S
E
L
L
N
V
F
M
I
I
Q
D
---------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
37.66
23%
27
- C11 -
2QZE
-
MCE_MIMIV
A:
[92-196]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
I
---
G
E
F
-
I
T
K
F
S
----
K
A
S
S
N
D
I
S
R
Y
--
I
V
S
L
D
P
S
D
--------
D
-----
I
-----
E
I
V
Y
K
N
R
---
K
L
I
G
--
I
D
N
W
A
I
T
I
K
S
T
--
E
E
I
--
P
L
V
A
G
------
K
S
K
I
S
K
P
K
I
T
G
S
E
R
I
M
Y
R
Y
K
----
T
R
Y
S
F
T
I
N
K
N
S
R
I
D
I
T
D
--------------
V
K
S
---
S
P
I
I
W
K
L
M
T
V
P
S
N
Y
E
L
E
L
E
L
I
N
K
I
D
I
-----
N
T
L
E
S
E
L
L
N
V
F
M
I
I
Q
----------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
37.28
23%
24
- C11 -
2QY2
2
MCE_MIMIV
A:
[93-197]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
I
---
G
E
F
-
I
T
K
F
S
----
K
A
S
S
N
D
I
S
R
Y
--
I
V
S
L
D
P
S
D
--------
D
-----
I
-----
E
I
V
Y
K
N
R
G
S
G
K
L
I
G
--
I
D
N
W
A
I
T
I
K
S
T
--
E
E
I
--
P
L
V
A
---------
K
I
S
K
P
K
I
T
G
S
E
R
I
M
Y
R
Y
K
----
T
R
Y
S
F
T
I
N
K
N
S
R
I
D
I
T
D
--------------
V
K
S
---
S
P
I
I
W
K
L
M
T
V
P
S
N
Y
E
L
E
L
E
L
I
N
K
I
D
I
-----
N
T
L
E
S
E
L
L
N
V
F
M
I
I
Q
D
---------------------------------------------------------------------------------------------------------------
19
HHSearch
37.14
6%
32
- C10 -
2HBW
1
?
A:
[21-70]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
A
L
N
L
Y
-
D
S
---
P
E
C
T
-
S
-
L
------------
A
T
Q
A
A
V
G
R
H
-----
L
Q
V
T
S
N
Q
-
Q
---
G
A
A
--
V
E
V
C
L
C
-
E
D
D
Y
P
G
W
L
S
L
------------------
20
HHSearch
36.80
16%
148
- C10 -
3NPF
3
?
A:
[19-54]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
C
N
L
R
-
E
E
---
G
K
F
T
-
S
G
M
------------
S
T
Q
A
L
L
G
M
P
-----
V
K
V
L
Q
---
Y
---
N
G
W
--
Y
E
I
Q
T
P
D
D
Y
T
G
W
V
H
R
M
V
------------------