@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1510: (2015-12-08 )
MEKNTWKKLLVSTAALSVVAGGAIAATHSNSVDAASKTTIKLWVPTDSKASYKAIVKKFEKENKGVTVKMIESNDSKAQENVKKDPSKAADVFSLPHDQLGQLVESGVIQEIPEQYSKEIAKNDTKQSLTGAQYKGKTYAFPFGIESQVLYYNKTKLTADDVKSYETITSKGKFGQQLKAANSYVTGPLFLSVGDTLFGKSGEDAKGTNWGNEAGVSVLKWIADQKKNDGFVNLTAENTMSKFGDGSVHAFESGPWDYDAAKKAVGEDKIGVAVYPTMKIGDKEVQQKAFLGVKLYAVNQAPAGSNTKRISASYKLAAYLTNAESQKIQFEKRHIVPANSSIQSSDSVQKDELAKAVIEMGSSDKYTTVMPKLSQMSTFWTESAAILSDTYSGKIKSSDYLKRLKQFDKDIAKTK
Atome Classification :
(20 SA)
.........10........20........30........40.....--.---..-50........60.-.......70...-.....80....-.--.-..90...-...-..100.......110....--...-120.........130.......140.......150.....-----.------.160---....---...---------.170..---..------.-----..--180--.-------...-.----....190....-...200..---.--.....210-........--------220......--.-230..---.---....--.240--.......250.......260...----.---...270.......280.......290.......300.......310......-.-320.-......330..-.-....340.......350.......360.......370.......380.......390..--.-.----...400....-...410...-----------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MEK
N
T
W
K
K
L
L
V
S
T
A
A
L
S
V
VAG
G
A
I
A
ATHSNSVDAAS
K
T
T
I
K
L
W
VPT--D---SK-
A
S
Y
K
A
I
V
K
K
F
E
KE-NK
G
V
T
V
K
M
IESN-D
S
K
A
Q
E
N
V
KKD-P--S-KAA
D
V
FS-L
P
H
-
D
Q
L
G
Q
L
V
E
S
G
V
I
Q
E
I
P
E
Q
Y
--
S
K
E
-
I
--AKNDTKQSLTGAQYKG
K
T
Y
A
F
PFGIE
S
Q
V
L
Y
Y
NKTKL-----
T
------
A
D
D
----
V
K
S
Y
---
E
T
I---------TSKGKF---
G
Q
------
Q
-----
L
K
--A----A-------NSY-V----TG
P
L
F
L
SVG
D
T
-
L
FGKS-GE---D--AKGTNWG--
N
E
A
G
V
S
V
L
--------
K
W
I
A
DQKKN--D-G
F
-
V
N
---
L
---TAEN--
T
M
S
K--FGDG
S
V
H
AFESGPW
D
Y
D
A
A
K
K
AV----G---EDKI
G
V
A
V
Y
P
T
MKI
G
D
K
E
V
Q
Q
K
AFL
G
V
K
L
Y
A
V
NQAPAGSNT
K
R
I
S
A
S
Y
K
L
A
A
-
Y
-
L
TNA-ES
Q
K
I
Q
F
E
K
R
H
-I-VPANSSIQSSDSV
Q
K
D
E
L
A
K
A
V
I
EMGSSDKY
T
T
V
M
P
K
L
S
Q
M
S
T
F
W
TE
S
A
A
I
LSDTYSGK--I-K----
S
S
D
Y
L
K
R
L
K
Q
-
F
D
K
D
IAKTK-----------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
82.16
22%
-35
- C1 -
1URS
1
?
A:
[30-393]
-------------------------------------
Q
T
I
T
V
W
S
W
Q
--
T
G
P
-
E
L
-
Q
D
V
K
Q
I
A
A
Q
W
A
K
A
-
H
G
D
-
K
V
I
V
V
D
Q
S
S
N
P
K
G
F
Q
F
Y
A
T
A
-
A
R
T
G
-
K
G
P
D
V
V
F
-
G
M
P
H
D
N
N
G
V
F
A
E
E
G
L
M
A
P
V
P
S
G
V
--
L
N
-----
T
G
L
Y
A
P
N
T
I
D
A
I
K
V
N
G
T
M
Y
S
V
P
V
S
V
Q
V
A
A
I
Y
Y
N
K
K
L
V
-----
P
------
Q
-
P
----
P
Q
T
W
---
A
E
F
---------
V
K
D
A
N
A
---
H
G
F
-----
M
-----
Y
D
--
Q
----
A
-------
N
L
Y
-
F
----
D
Y
A
I
I
G
G
Y
G
G
Y
-
V
F
K
D
N
-
N
G
TL-
D
--
P
N
N
I
G
L
D
--
T
P
G
A
V
Q
A
Y
--------
T
L
M
R
D
M
V
S
K
--
Y
-
H
W
-
M
T
PS-
T
---
N
G
S
I
--
A
K
A
E
--
F
L
A
G
K
I
G
M
Y
V
S
G
P
W
D
T
A
D
I
E
K
A
-----
K
----
I
D
F
G
V
T
P
W
P
T
L
P
N
-
G
K
H
--
A
T
P
F
L
G
V
I
T
A
F
V
N
K
E
S
K
-----
T
Q
A
A
D
W
S
L
V
Q
-
A
-
L
T
S
A
-
Q
A
Q
Q
M
Y
F
R
D
S
Q
-
Q
-
I
P
A
L
L
S
V
Q
R
S
S
A
V
Q
S
S
P
T
F
K
A
F
V
E
Q
L
---
R
Y
A
V
P
M
P
N
I
P
Q
M
Q
A
V
W
Q
A
M
-
S
I
L
Q
N
I
I
A
G
K
--
V
-
S
----
P
E
Q
G
A
K
D
F
V
Q
-
N
I
Q
K
G
---------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
80.87
29%
-33
- C1 -
2XD2
-
MALX_STRPN
A:
[43-398]
---------------------------------------
L
T
V
Y
V
D
E
--
G
---
Y
K
-
S
Y
I
E
E
V
A
K
A
Y
E
K
E
A
G
V
K
V
T
L
K
T
G
D
A
L
-
G
G
L
D
K
L
S
L
D
N
Q
-
N
--
G
-
N
V
P
D
V
M
M
-
A
P
Y
-
D
R
V
G
S
L
G
S
D
G
Q
L
S
E
V
--
K
L
--
S
D
G
-
A
--
K
T
D
D
T
T
K
S
L
V
T
A
A
-
N
G
K
V
Y
G
A
P
A
V
I
E
S
L
V
M
Y
Y
N
K
-
D
L
-----
V
------
K
D
A
----
P
K
T
F
A
D
L
E
N
L
---------
A
K
D
S
K
Y
AFA
G
E
------
D
-----
G
K
--
T
----
T
AFLADWT
N
F
Y
-
Y
----
T
Y
G
L
L
A
G
N
G
A
Y
-
V
F
G
Q
N
-
G
K
---
D
--
A
K
D
I
G
L
A
--
N
D
G
S
I
V
G
I
N
Y
A
K
S
W
Y
E
K
W
P
K
G
M
Q
D
T
--
E
-
G
A
-
G
N
---
L
---
I
------
Q
T
Q
--
F
Q
E
G
K
T
A
A
I
I
D
G
P
W
K
A
Q
A
F
K
D
A
---------
K
V
N
Y
G
V
A
T
I
P
T
L
P
N
G
K
---
E
Y
A
A
F
G
G
G
K
A
W
V
I
P
Q
A
-----
V
K
N
L
E
A
S
Q
K
F
V
D
-
F
-
L
V
A
T
-
E
Q
Q
K
V
L
Y
D
K
T
N
-
E
-
I
P
A
N
T
E
A
R
S
Y
A
E
G
K
N
D
E
L
T
T
A
V
I
K
Q
F
---
K
N
T
Q
P
L
P
N
I
S
Q
M
S
A
V
W
D
P
A
K
N
M
L
F
D
A
V
S
G
Q
--
K
-
D
----
A
K
T
A
A
N
D
A
V
T
-
L
I
K
E
T
L
K
Q
K
-----------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
79.94
20%
-35
- C1 -
2GH9
1
?
A:
[2-376]
--------------------------------------
K
I
T
V
W
T
H
F
--
G
G
P
-
E
L
-
E
W
L
K
E
Q
A
R
T
F
E
R
--
T
S
G
T
K
V
E
V
V
E
V
P
-
F
A
E
I
K
Q
K
F
I
L
G
-
A
PQ
G
-
Q
A
A
D
L
V
V
T
V
P
H
-
D
W
V
G
E
M
A
Q
A
G
V
L
E
P
V
G
K
Y
V
--
T
Q
A
-
Y
--
L
A
D
L
Q
G
V
A
V
E
A
F
T
F
G
G
R
L
M
G
L
P
A
F
A
E
S
V
A
L
I
Y
N
K
K
Y
V
-----
K
------
E
-
P
----
P
R
T
W
---
E
E
F
---------
L
A
L
A
Q
K
---
L
T
TGA---
T
-----
F
G
--
F
LYNI
G
-------
D
P
Y
-
F
----
N
F
G
F
F
K
A
F
G
A
E
N
V
F
A
K
D
-
A
K
G
N
L
D
--
P
T
K
L
L
I
G
--
G
E
V
G
E
K
A
L
--------
Q
F
I
K
D
L
R
F
K
--
Y
-
N
L
-
V
P
EG-
V
---
D
Y
G
V
--
A
D
G
A
--
F
K
D
G
A
L
A
M
I
L
N
G
P
W
A
L
G
D
Y
K
K
A
-----
K
----
V
D
F
G
I
A
P
F
P
V
P
P
G
A
K
N
--
P
W
G
P
F
L
G
V
Q
G
V
V
V
N
A
Y
S
K
-----
N
K
T
Q
A
V
N
F
A
K
-
T
-
L
V
T
G
-
R
N
L
V
A
F
N
Q
A
G
G
-
R
-
I
P
V
S
K
S
A
V
K
Q
L
--
E
K
D
P
V
V
A
G
F
S
K
V
---
F
P
L
G
A
P
M
P
N
I
P
E
M
G
K
V
W
G
P
W
G
N
A
I
S
L
A
I
Q
R
P
--
D
S
N
----
V
---
K
K
I
V
E
D
-
M
V
A
E
I
K
K
A
I
-----------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
79.81
21%
-32
- C1 -
3K01
1
?
A:
[24-406]
---------------------------------
V
E
L
S
G
T
V
T
F
W
D
T
S
--
N
EA-
E
K
-
A
T
Y
Q
A
L
A
E
G
F
E
K
E
-
H
P
K
V
D
V
K
Y
V
N
V
P
-
F
G
E
A
N
A
K
F
K
N
A
-
A
G
G
N
S
G
A
P
D
V
M
R
-
T
E
V
-
A
W
V
A
D
F
A
S
I
G
Y
L
A
P
L
D
G
T
P
--
A
L
D
-
D
--
G
S
D
H
L
P
Q
A
A
A
S
T
R
Y
E
G
K
T
Y
A
V
P
Q
V
I
D
T
L
A
L
F
Y
N
K
E
L
L
-----
T
------
K
A
G
VEV-
P
G
S
V
---
A
E
L
---------
K
T
A
A
A
E
---
I
T
E
K
TGAT
G
-----
L
Y
--
L
RG--
D
-------
D
P
Y
-
W
----
F
L
P
Y
L
Y
G
E
G
G
D
-
L
V
D
E
K
-
N
K
---
T
-----
V
T
V
D
--
D
E
A
G
V
R
A
Y
--------
R
V
I
K
D
L
V
D
S
--
K
-
A
A
-
I
T
D
AS
D
---
G
W
N
N
--
M
Q
N
A
--
F
K
S
G
K
V
A
M
M
V
N
G
P
W
A
I
E
D
V
K
A
G
A
----
R
FKD
A
G
N
L
G
V
A
P
V
P
A
G
S
A
-
G
Q
-
G
---
S
P
Q
G
G
W
N
L
S
V
Y
A
G
S
K
-----
N
L
D
A
S
Y
A
F
V
K
-
Y
-
M
S
S
A
-
K
V
Q
Q
Q
T
T
E
K
L
S
-
L
-
L
P
T
R
T
S
V
Y
E
V
P
S
V
A
D
N
E
M
V
K
F
F
K
P
A
---
V
D
K
A
V
E
R
P
W
I
A
E
G
N
A
L
F
E
P
I
R
L
Q
M
A
N
V
L
S
G
E
--
T
-
S
----
P
D
E
A
A
A
N
T
G
D
-
A
Y
R
K
L
L
K
D
Y
-----------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
78.47
27%
-35
- C1 -
2XD3
3
MALX_STRPN
A:
[36-406]
--------------------------------------
E
L
T
V
Y
V
D
E
--
G
---
Y
K
-
S
Y
I
E
E
V
A
K
A
Y
E
K
E
--
A
G
V
K
V
T
L
K
T
G
D
-
A
L
G
G
L
D
K
L
S
L
D
-
N
Q
N
G
-
N
V
P
D
V
M
M
-
A
P
Y
-
D
R
V
G
S
L
G
S
D
G
Q
L
S
E
V
K
L
S
D
--
G
-
A
-
K
--
T
D
D
T
T
K
S
L
V
--
T
A
A
N
G
K
V
Y
G
A
P
A
V
I
E
S
L
V
M
Y
Y
N
K
D
L
V
-----
K
------
D
A
-----
P
K
T
F
---
A
D
L
---------
E
N
L
A
K
D
---
S
K
Y-----
A
-----
F
A
--
G
ED--
G
KTTAFL-
A
D
W
-
T
NFYY
T
Y
G
L
L
A
G
N
G
A
Y
-
V
F
G
Q
N
-
G
K
---
D
--
A
K
D
I
G
L
A
--
N
D
G
S
I
V
G
I
--------
N
Y
A
K
S
W
Y
E
K
WP
K
-
G
M
-
Q
D
---
T
EG-
A
G
N
L
--
I
Q
T
Q
--
F
Q
E
G
K
T
A
A
I
I
D
G
P
W
K
A
Q
A
F
K
D
A
-----
K
----
V
N
Y
G
V
A
T
I
P
T
L
P
N
-
G
K
E
--
Y
A
A
F
G
G
G
K
A
W
V
I
P
Q
A
V
K
-----
N
L
E
A
S
Q
K
F
V
D
-
F
-
L
V
A
T
-
E
Q
Q
K
V
L
Y
D
K
T
N
-
E
-
I
P
A
N
T
E
A
R
S
Y
A
E
G
K
N
D
E
L
T
T
A
V
I
K
Q
F
---
K
N
T
Q
P
L
P
N
I
S
Q
M
S
A
V
W
D
P
A
K
N
M
L
F
D
A
V
S
G
Q
--
K
-
D
----
A
K
T
A
A
N
D
A
V
T
-
L
I
K
E
T
L
--------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
77.70
29%
-32
- C1 -
2XD3
3
MALX_STRPN
A:
[37-392]
---------------------------------------
L
T
V
Y
V
D
E
--
G
---
Y
K
-
S
Y
I
E
E
V
A
K
A
Y
E
K
E
A
G
V
K
V
T
L
K
T
G
D
A
L
-
G
G
L
D
K
L
S
L
D
N
Q
-
N
--
G
-
N
V
P
D
V
M
M
-
A
P
Y
-
D
R
V
G
S
L
G
S
D
G
Q
L
S
E
V
--
K
L
--
S
D
G
-
A
--
K
T
D
D
T
T
K
S
L
V
T
A
A
-
N
G
K
V
Y
G
A
P
A
V
I
E
S
L
V
M
Y
Y
N
K
-
D
L
-----
V
------
K
D
A
----
P
K
T
F
A
D
L
E
N
L
---------
A
K
D
S
K
Y
AFA
G
E
------
D
-----
G
K
--
T
----
T
AFLADWT
N
F
Y
-
Y
----
T
Y
G
L
L
A
G
N
G
A
Y
-
V
F
G
Q
N
-
G
K
---
D
--
A
K
D
I
G
L
A
--
N
D
G
S
I
V
G
I
N
Y
A
K
S
W
Y
E
K
W
P
K
G
M
Q
D
T
--
E
-
G
A
-
G
N
---
L
---
I
------
Q
T
Q
--
F
Q
E
G
K
T
A
A
I
I
D
G
P
W
K
A
Q
A
F
K
D
A
---------
K
V
N
Y
G
V
A
T
I
P
T
L
P
N
G
K
---
E
Y
A
A
F
G
G
G
K
A
W
V
I
P
Q
A
-----
V
K
N
L
E
A
S
Q
K
F
V
D
-
F
-
L
V
A
T
-
E
Q
Q
K
V
L
Y
D
K
T
N
-
E
-
I
P
A
N
T
E
A
R
S
Y
A
E
G
K
N
D
E
L
T
T
A
V
I
K
Q
F
---
K
N
T
Q
P
L
P
N
I
S
Q
M
S
A
V
W
D
P
A
K
N
M
L
F
D
A
V
S
G
Q
--
K
-
D
----
A
K
T
A
A
N
D
A
V
T
-
L
I
K
E
T
L
--------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
77.60
23%
-34
- C1 -
3WOA
1
MALE_ECOLI (first)
A:
[35-415]
-------------
E
S
V
A
D
K
M
G
M
G
Q
S
G
S
G
----
M
K
I
E
E
G
K
L
V
I
W
I
N
G
--
D
K--
G
Y
-
N
G
L
A
E
V
G
K
K
F
E
K
D
--
T
G
I
K
V
T
V
E
H
P
---
D
K
L
E
E
K
F
P
Q
V
-
A
A
T
G
-
D
G
P
D
I
I
F
-
W
A
H
-
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
P
D
K
--
A
---
F
--
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
-----
P
------
N
-
P
----
P
K
T
W
---
E
E
I
---------
P
A
L
D
K
E
---
L
K
A
K
GKS-
A
-----
L
M
--
F
NL--
Q
-------
E
P
Y
-
F
----
T
W
P
L
I
A
A
D
G
G
Y
-
A
F
K
Y
E
-
N
G
---
K
YD
I
K
D
V
G
V
D
--
N
A
G
A
K
A
G
L
--------
T
F
L
V
D
L
I
K
N
--
K
-
H
M
-
N
A
---
D
T--
D
Y
S
I
--
A
E
A
A
--
F
N
K
G
E
T
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
-----
K
----
V
N
Y
G
V
T
V
L
P
T
F
K
G
-
Q
P
S
---
K
P
F
V
G
V
L
S
A
G
I
N
A
A
S
P
-----
N
K
E
L
A
K
E
F
L
E
N
Y
-
L
L
T
D
-
E
G
L
E
A
V
N
K
D
K
P
-
L
G
A
V
A
L
K
S
Y
-
E
E
E
-
L
A
K
D
P
R
I
A
A
T
M
E
N
---
A
Q
K
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
G
R
--
Q
-
T
----
V
D
E
A
L
K
D
A
Q
T
---------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
77.54
21%
-27
- C1 -
3MP6
2
MALE_ECOLI (first)
A:
[1-517]
--------------------------------
M
K
I
E
E
G
K
L
V
I
W
I
N
G
--
D
K--
G
Y
-
N
G
L
A
E
V
G
K
K
F
E
K
D
-
T
-
G
I
K
V
T
V
E
H
P
D
-
K
L
E
E
K
F
P
Q
V
A
A
-
T
--
G
-
D
G
P
D
I
I
F
-
W
A
H
-
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
--
T
P
--
D
K
A
-
F
--
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
PNPPK
T
------
W
E
E
----
I
P
A
L
D
--
K
E
L
---------
K
A
K
G
K
S
---
A
L
------
M
-----
F
N
--
L
----
Q
-------
E
P
Y
-
F
----
T
W
P
L
I
A
A
D
G
G
Y
-
A
F
K
Y
E
-
N
G
---
K
--
Y
D
I
K
D
V
G
VD
N
A
G
A
K
A
G
L
--------
T
F
L
V
D
L
I
K
N
--
K
-
H
M
N
A
D
---
T
---
D
Y
S
I
--
A
E
A
A
--
F
N
K
G
E
T
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
---------
K
V
N
Y
G
V
T
V
L
P
T
F
K
----
G
Q
P
S
K
P
F
V
G
V
L
S
A
G
I
N
-----
A
A
S
P
N
K
E
L
A
K
E
F
L
E
-
N
-
Y
L
L
T
-
D
E
G
L
E
A
V
N
K
D
K
-
P
-
L
G
A
V
A
L
K
S
Y
E
E
E
L
A
K
D
P
R
I
A
A
T
M
E
N
A
Q
K
---
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
G
R
--
Q
-
T
----
V
D
E
A
L
A
A
A
Q
T
N
A
A
A
E
F
G
S
S
Y
WTSEYNPNAPILVG
S
E
V
A
Y
K
P
RG
E
W
I
Q
C
E
V
LKVVADGT
R
F
E
V
R
DPEPDELGNS
G
K
V
Y
K
C
N
RKELLLIPPGFPTKNYPPG
T
K
V
L
A
R
Y
P
ETT
T
F
Y
P
A
I
V
IGTKRDG
T
C
R
L
R
F
D
GEK
E
T
E
V
T
RRL
V
L
P
S
PTALA
39
HHSearch
76.56
23%
-35
* C1 *
3PY7
1
MALE_ECOLI (first)
A:
[4-373]
-----------------------------------
E
E
G
K
L
V
I
W
I
N
G
--
D
K--
G
Y
-
N
G
L
A
E
V
G
K
K
F
E
K
D
--
T
G
I
K
V
T
V
E
H
---
P
D
K
L
E
E
K
F
P
Q
V
-
A
A
T
G
-
D
G
P
D
I
I
F
-
W
A
H
-
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
P
A
A
--
A
---
F
--
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
-----
P
------
N
-
P
----
P
K
T
W
---
E
E
I
---------
P
A
L
D
K
E
---
L
K
A
K
GKS-
A
-----
L
M
--
F
NL--
Q
-------
E
P
Y
-
F
----
T
W
P
L
I
A
A
D
G
G
Y
-
A
F
K
Y
E
-
N
G
---
K
YD
I
K
D
V
G
V
D
--
N
A
G
A
K
A
G
L
--------
T
F
L
V
D
L
I
K
N
--
K
-
H
M
-
N
A
D--
T
---
D
Y
S
I
--
A
E
A
A
--
F
N
K
G
E
T
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
-----
A
----
V
N
Y
G
V
T
V
L
P
T
F
K
G
-
Q
P
---
S
K
P
F
V
G
V
L
S
A
G
I
N
A
A
S
P
-----
N
K
E
L
A
K
E
F
L
E
N
Y
-
L
L
T
D
-
E
G
L
E
A
V
N
K
D
K
P
-
L
G
A
V
A
L
K
S
Y
E
-
E
E
-
L
A
K
D
P
R
I
A
A
T
M
E
N
---
A
Q
K
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
G
R
--
Q
-
T
----
V
D
A
A
L
A
A
A
Q
T
-
N
A
A
A
M
D
D
L
D
-----------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
75.21
21%
-33
- C1 -
2ZYO
1
?
A:
[13-390]
-------------------------------
K
S
E
G
K
P
D
K
L
V
V
W
E
N
A
--
D
D
G
V
Q
L
-
N
N
T
K
K
W
A
G
E
F
T
K
K
--
T
G
I
Q
V
E
V
V
P
V
A
-
L
L
K
Q
Q
E
K
L
T
L
D
-
G
P
A
G
-
K
G
A
D
L
V
T
-
W
P
H
-
D
R
L
G
E
A
V
T
K
G
L
L
Q
P
I
Q
V
D
N
----
S
-
V
--
K
N
Q
F
D
D
V
A
M
K
A
L
T
Y
G
G
K
L
Y
G
L
P
K
A
I
E
S
V
A
L
I
Y
N
K
K
L
M
-----
G
------
Q
-
V
----
P
A
T
Y
---
D
E
L
---------
F
Q
Y
A
K
A
---
N
N
KPDEQ-
K
YG---
V
L
--
F
----
E
A------
N
N
F
-
Y
Y---
T
Y
F
L
F
A
A
K
G
A
A
-
V
F
K
E
Q
-
D
G
---
T
LD
P
N
E
I
G
L
N
--
S
P
E
A
V
Q
G
M
--------
N
E
V
Q
K
W
F
T
E
--
A
-
R
L
-
P
Q
S--
L
---
K
A
D
T
--
V
N
G
L
--
F
K
S
G
K
V
A
A
V
I
N
G
P
W
A
I
K
D
Y
Q
A
A
-----
G
----
I
N
V
G
V
A
P
L
P
K
I
D
G
-
K
D
A
---
Q
T
F
I
G
V
K
G
W
Y
L
S
A
Y
S
K
-----
Y
P
K
Y
A
T
E
L
M
Q
-
F
-
L
T
S
K
-
E
A
L
A
S
R
F
K
E
T
G
-
E
-
I
P
P
Q
K
E
L
L
N
D
P
M
I
K
N
N
P
V
V
N
G
F
A
K
Q
A
---
S
K
G
V
P
M
P
S
I
P
E
M
G
V
V
W
E
P
I
N
N
A
H
T
F
V
A
Q
G
K
--
Q
-
T
----
P
E
Q
A
L
N
D
A
V
K
-
I
M
K
E
K
I
Q
T
M
-----------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
74.93
24%
-30
- C1 -
1HSJ
2
MALE_ECOLI (first)
A:
[3-370]
-----------------------------------
E
E
G
K
L
V
I
W
I
N
G
--
D
K--
G
Y
-
N
G
L
A
E
V
G
K
K
F
E
K
D
--
T
G
I
K
V
T
V
E
H
P
---
D
K
L
E
E
K
F
P
Q
V
-
A
AT
G
-
D
G
P
D
I
I
F
-
W
A
H
-
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
P
D
K
--
A
---
F
--
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
-----
P
------
N
-
P
----
P
K
T
W
---
E
E
I
---------
P
A
L
D
K
E
---
L
K
A
K
GKS-
A
-----
L
M
--
F
NL--
Q
-------
E
P
Y
-
F
----
T
W
P
L
I
A
A
D
G
G
Y
-
A
F
K
Y
E
-
N
G
---
K
YD
I
K
D
V
G
V
D
--
N
A
G
A
K
A
G
L
--------
T
F
L
V
D
L
I
K
N
--
K
-
H
M
-
N
A
---
D
T--
D
Y
S
I
--
A
E
A
A
--
F
N
K
G
E
T
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
-----
K
----
V
N
Y
G
V
T
V
L
P
T
F
K
G
-
Q
P
S
---
K
P
F
V
G
V
L
S
A
G
I
N
A
A
S
P
-----
N
K
E
L
A
K
E
F
L
E
N
Y
-
L
L
T
D
-
E
G
L
E
A
V
N
K
D
K
P
L
G
-
A
V
A
L
K
S
Y
E
-
E
E
-
L
A
K
D
P
R
I
A
A
T
M
E
N
---
A
Q
K
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
G
R
--
Q
-
T
----
V
D
E
A
L
A
A
A
Q
T
-
N
A
A
A
E
F
M
S
K
-----------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
74.76
23%
-33
- C1 -
2XZ3
5
ENV_BLV (first)
A:
[4-372]
-----------------------------------
E
E
G
K
L
V
I
W
I
N
G
--
D
K--
G
Y
-
N
G
L
A
E
V
G
K
K
F
E
K
D
--
T
G
I
K
V
T
V
E
H
---
P
D
K
L
E
E
K
F
P
Q
V
-
A
A
T
G
-
D
G
P
D
I
I
F
-
W
A
H
-
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
P
D
K
--
A
---
F
--
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
-----
P
------
N
-
P
----
P
K
T
W
---
E
E
I
---------
P
A
L
D
K
E
---
L
K
A
K
GKS-
A
-----
L
M
--
F
NL--
Q
-------
E
P
Y
-
F
----
T
W
P
L
I
A
A
D
G
G
Y
-
A
F
K
Y
E
-
N
G
---
K
YD
I
K
D
V
G
V
D
--
N
A
G
A
K
A
G
L
--------
T
F
L
V
D
L
I
K
N
--
K
-
H
M
-
N
A
---
D
T--
D
Y
S
I
--
A
E
A
A
--
F
N
K
G
E
T
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
-----
K
----
V
N
Y
G
V
T
V
L
P
T
F
K
G
-
Q
P
S
---
K
P
F
V
G
V
L
S
A
G
I
N
A
A
S
P
-----
N
K
E
L
A
K
E
F
L
E
N
Y
-
L
L
T
D
-
E
G
L
E
A
V
N
K
D
K
P
-
L
G
A
V
A
L
K
S
Y
-
E
E
E
-
L
A
K
D
P
R
I
A
A
T
M
E
N
---
A
Q
K
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
G
R
--
Q
-
T
----
V
D
A
A
L
A
A
A
Q
T
-
N
A
A
A
L
S
H
Q
R
-----------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
74.41
23%
-29
- C1 -
3DM0
2
GBLPA_ARATH (first)
A:
[3-371]
-----------------------------------
E
E
G
K
L
V
I
W
I
N
G
--
D
K--
G
Y
-
N
G
L
A
E
V
G
K
K
F
E
K
D
--
T
G
I
K
V
T
V
E
H
---
P
D
K
L
E
E
K
F
P
Q
V
-
A
A
T
G
-
D
G
P
D
I
I
F
-
W
A
H
-
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
P
A
A
--
A
---
F
--
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
-----
P
------
N
-
P
----
P
K
T
W
---
E
E
I
---------
P
A
L
D
K
E
---
L
K
A
K
G---
K
-----
S
A
L
M
F
NL--
Q
-------
E
P
Y
-
F
----
T
W
P
L
I
A
A
D
G
G
Y
-
A
F
K
Y
E
N
G
K
Y--
D
--
I
K
D
V
G
V
D
--
N
A
G
A
K
A
G
L
--------
T
F
L
V
D
L
I
K
N
--
K
-
H
M
-
N
A
---
D
T--
D
Y
S
I
--
A
E
A
A
--
F
N
K
G
E
T
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
-----
A
----
V
N
Y
G
V
T
V
L
P
T
F
K
G
-
Q
P
---
S
K
P
F
V
G
V
L
S
A
G
I
N
A
A
S
P
-----
N
K
E
L
A
K
E
F
L
E
N
Y
-
L
L
T
D
-
E
G
L
E
A
V
N
K
D
K
P
-
L
-
G
A
V
A
L
K
S
Y
E
E
E
-
L
A
K
D
P
R
I
A
A
T
M
E
N
---
A
Q
K
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
G
R
--
Q
-
T
----
V
D
A
A
L
A
A
A
Q
T
-
N
A
A
A
G
L
V
L
K
-----------------------------------------------------------------------------------------------------------------------------------
45
Fugue
73.28
19%
-27
- C1 -
3D4G
4
ZP3_MOUSE
A:
[3-473]
----------------------------------
T
E
E
G
K
L
V
I
W
I
N
G
--
D
K--
G
Y
-
N
G
L
A
E
V
G
K
K
F
E
K
D
-
T
-
G
I
K
V
T
V
E
H
P
D
-
K
L
E
E
K
F
P
Q
V
A
A
-
T
--
G
-
D
G
P
D
I
I
F
-
W
A
H
-
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
--
P
--
D
K
A
-
F
--
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
-----
P
NPPKTW
E
E
I
----
P
A
L
D
---
K
E
L
---------
K
A
K
G
K
S
---
A
L
------
M
-----
F
N
--
L
----
Q
-------
E
P
Y
-
F
----
T
W
P
L
I
A
A
D
G
G
Y
-
A
F
K
Y
E
-
N
G
---
K
--
Y
D
I
K
D
V
G
VD
N
A
G
A
K
A
G
L
--------
T
F
L
V
D
L
I
K
N
--
K
-
H
M
N
A
D
---
T
---
D
Y
S
I
--
A
E
A
A
--
F
N
K
G
E
T
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
-----------
K
V
N
Y
G
V
T
V
L
P
T
F
K
G
Q
P
S
--
K
P
F
V
G
V
L
S
A
G
I
N
-----
A
A
S
P
N
K
E
L
A
K
E
F
L
E
-
N
-
Y
L
L
T
-
D
E
G
L
E
A
V
N
K
D
K
-
P
-
L
G
A
V
A
L
K
S
Y
E
E
E
L
A
K
D
P
R
I
A
A
T
M
E
N
A
Q
K
---
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
G
R
--
Q
-
T
----
V
D
A
A
L
A
A
A
Q
T
-
N
A
A
A
V
K
V
E
C
L
EA
E
L
V
V
T
V
S
RDLFGTG
K
L
V
Q
PGDLTLGSEGCQ
P
R
V
S
V
D
TD
V
V
R
F
NAQLHECSS
R
V
Q
M
T
KD
A
L
V
Y
S
T
F
L
L
H
D
PRPVSGLSILRTN
R
V
E
V
P
I
E
C
R
Y
P
R----------------------------------
27
HHSearch
72.16
19%
-31
- C1 -
1ELJ
4
MALE_PYRFU
A:
[4-377]
-----------------------------------
E
E
G
K
V
V
I
W
H
A
M
Q
P
N
---
E
L
-
E
V
F
Q
S
L
A
E
E
Y
M
A
L
-
C
P
E
V
E
I
V
F
E
Q
K
P
---
N
L
E
D
A
L
K
A
A
-
I
PT
G
-
Q
G
P
D
L
F
I
-
W
A
H
-
D
W
I
G
K
F
A
E
A
G
L
L
E
P
I
D
E
Y
V
--
T
E
D
-
L
--
L
N
E
F
A
P
M
A
Q
D
A
M
Q
Y
K
G
H
Y
Y
A
L
P
F
A
A
E
T
V
A
I
I
Y
N
K
E
M
V
-----
S
------
E
-
P
----
P
K
T
F
---
D
E
M
---------
K
A
I
M
E
K
---
Y
Y
------
D
PANEK
Y
G
--
I
----
A
W
P
I
----
N
A
Y
-
F
----
I
S
A
I
A
Q
A
F
G
G
Y
-
Y
F
D
D
K
-
T
E
--------
Q
P
G
L
D
--
K
P
E
T
I
E
G
F
--------
K
F
F
F
T
E
I
W
P
--
Y
-
M
A
-
P
T
---
G
---
D
Y
N
T
--
Q
Q
S
I
--
F
L
E
G
R
A
P
M
M
V
N
G
P
W
S
I
N
D
V
K
K
A
-----
G
----
I
N
F
G
V
V
P
L
P
P
I
I
K
D
G
K
E
Y
W
P
R
P
Y
G
G
V
K
L
I
Y
F
A
A
G
I
K
-----
N
K
D
A
A
W
K
F
A
K
-
W
-
L
T
T
S
E
E
S
I
K
T
L
A
L
E
L
G
-
Y
-
I
P
V
L
T
K
V
L
D
D
P
E
I
K
N
D
P
V
I
Y
G
F
G
Q
A
---
V
Q
H
A
Y
L
M
P
K
S
P
K
M
S
A
V
W
G
G
V
D
G
A
I
N
E
I
L
Q
D
P
QN
A
-
D
----
I
---
E
G
I
L
K
K
-
Y
Q
Q
E
I
L
N
N
M
-----------------------------------------------------------------------------------------------------------------------------------
42
Fugue
71.25
21%
-23
- C1 -
2VGQ
6
MALE_ECOLI (first)
A:
[17-477]
----------------------------------
I
E
E
G
K
L
V
I
W
I
N
G
--
D
K--
G
Y
-
N
G
L
A
E
V
G
K
K
F
E
K
D
-
T
-
G
I
K
V
T
V
E
H
P
D
-
K
L
E
E
K
F
P
Q
V
A
A
-
T
--
G
-
D
G
P
D
I
I
F
-
W
A
H
-
D
R
F
G
G
Y
A
Q
S
G
L
L
A
E
I
T
--
P
--
D
K
A
-
F
--
Q
D
K
L
Y
P
F
T
W
D
A
V
R
Y
N
G
K
L
I
A
Y
P
I
A
V
E
A
L
S
L
I
Y
N
K
D
L
L
-----
P
NPPKTW
E
E
I
----
P
A
L
D
---
K
E
L
---------
K
A
K
G
K
S
---
A
L
------
M
-----
F
N
--
L
----
Q
-------
E
P
Y
-
F
----
T
W
P
L
I
A
A
D
G
G
Y
-
A
F
K
Y
E
-
N
G
---
K
--
Y
D
I
K
D
V
G
VD
N
A
G
A
K
A
G
L
--------
T
F
L
V
D
L
I
K
N
--
K
-
H
M
N
A
D
---
T
---
D
Y
S
I
--
A
E
A
A
--
F
N
K
G
E
T
A
M
T
I
N
G
P
W
A
W
S
N
I
D
T
S
---------
K
V
N
Y
G
V
T
V
L
P
T
F
K
----
G
Q
P
S
K
P
F
V
G
V
L
S
A
G
I
N
-----
A
A
S
P
N
K
E
L
A
K
E
F
L
E
-
N
-
Y
L
L
T
-
D
E
G
L
E
A
V
N
K
D
K
-
P
-
L
G
A
V
A
L
K
S
Y
E
E
E
L
A
K
D
P
R
I
A
A
T
M
E
N
A
Q
K
---
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
Y
A
V
R
T
A
V
I
N
A
A
S
G
R
--
Q
-
T
----
V
D
E
A
L
K
D
A
Q
T
-
N
S
A
M
A
F
A
E
D
K
T
Y
K
Y
I
C
R
N
FSNFCNVDVVEILPYLPCLT
A
R
D
Q
D
R
L
R
A
T
C
T
L
SG
N
R
D
T
L
W
H
L
F
N
T
L
Q
R
RPG
W
V
E
Y
F
I
A
A
L
R
G
C
EL
V
D
L
A
D
E
V
A
S
V
Y
Q--------------------------------------------
11
PsiBlast_PDB
70.82
26%
-43
- C1 -
4HW8
11
?
A:
[37-376]
-------------------------------
K
D
K
P
N
Q
L
T
--
M
W
V
D
G
--
D
---
K
Q
M
A
F
Y
K
K
I
T
D
Q
Y
T
K
K
-
T
-
G
I
K
V
K
L
V
N
I
G
-
Q
N
D
Q
L
E
N
I
S
L
D
A
P
--
A
G
K
G
P
D
I
F
F
-
L
A
H
-
D
N
T
G
S
A
Y
L
Q
G
L
A
A
E
I
--
K
L
--
S
K
D
-
E
--
L
K
G
F
N
K
Q
A
L
K
A
M
N
Y
D
N
K
Q
L
A
L
P
A
I
V
E
T
T
A
L
F
Y
N
K
-
K
L
-----
V
------
K
N
A
----
P
Q
T
L
---
E
E
V
E
A
N
A
A
K
LTD
S
K
K
K
Q
Y
---
G
M
------
L
-----
F
D
--
A
----
K
-------
N
F
Y
-
F
----
N
Y
P
F
L
F
G
N
D
D
Y
-
I
F
K
K
N
-
G
S
---
E
--
Y
D
I
H
Q
L
G
--
L
N
S
K
H
V
V
K
--------
N
A
E
R
L
Q
K
W
Y
--
D
K
G
Y
-
L
P
---
K
---
A
A
T
H
D
V
M
I
G
L
--
F
K
E
G
K
V
G
Q
F
V
T
G
P
W
N
I
N
E
Y
Q
E
T
F
----
G
---
K
D
-
L
G
V
T
T
L
P
T
----
D
G
G
K
P
M
K
P
F
L
G
V
R
G
W
Y
L
S
E
Y
-----
S
K
H
K
Y
W
A
K
D
L
M
L
-
Y
-
I
T
S
K
-
D
T
L
Q
K
Y
T
D
E
M
S
-
E
-
I
T
G
R
V
D
V
K
S
S
N
P
N
L
K
------
V
F
E
K
Q
A
--
R
H
A
E
P
M
P
N
I
P
E
M
R
Q
V
W
E
P
M
G
N
A
S
I
F
I
S
N
G
K
--
N
-
P
----
K
Q
A
L
D
E
A
T
N
D
-
I
T
Q
N
I
K
I
L
H
-----------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
70.43
20%
-27
- C1 -
2GHA
1
?
A:
[3-369]
-------------------------------------
P
K
L
T
I
W
C
S
E
--
K
---
Q
V
-
D
I
L
Q
K
L
G
E
E
F
K
A
K
-
Y
-
G
V
E
V
E
V
Q
Y
V
N
-
F
Q
D
I
K
S
K
F
L
T
A
-
A
PE
G
-
Q
G
A
D
I
I
V
-
G
A
H
-
D
W
V
G
E
L
A
V
N
G
L
I
E
P
I
P
N
F
S
--
D
------
L
K
N
F
Y
E
T
A
L
N
A
F
S
Y
G
G
K
L
Y
G
I
P
Y
A
M
E
A
I
A
L
I
Y
N
K
D
Y
V
-----
P
------
E
-
P
----
P
K
T
M
---
D
E
L
---------
I
E
I
A
K
Q
---
I
D
E
-----
E
F
GGEV
R
G
--
F
----
I
TSAA---
E
F
Y
-
Y
----
I
A
P
F
I
F
G
Y
G
G
Y
-
V
F
K
Q
T
-
E
K
GL-
D
--
V
N
D
I
G
L
A
--
N
E
G
A
I
K
G
V
--------
K
L
L
K
R
L
V
D
E
--
G
-
I
L
-
D
P
---
S
D--
N
Y
Q
I
--
M
D
S
M
--
F
R
E
G
Q
A
A
M
I
I
N
G
P
W
A
I
K
A
Y
K
D
A
-----
G
----
I
D
Y
G
V
A
P
I
P
D
L
E
P
G
-
V
P
--
A
R
P
F
V
G
V
Q
G
F
M
V
N
A
K
S
P
-----
N
K
L
L
A
I
E
F
L
T
-
S
F
I
A
K
K
-
E
T
M
Y
R
I
Y
L
G
D
P
-
R
-
L
P
S
R
K
D
V
L
E
L
V
--
K
D
N
P
D
V
V
G
F
T
L
S
---
A
A
N
G
I
P
M
P
N
V
P
Q
M
A
A
V
W
A
A
M
N
D
A
L
N
L
V
V
N
G
K
--
A
-
T
----
V
E
E
A
L
K
N
A
V
E
-
R
I
K
A
Q
I
Q
-------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
69.90
17%
-41
- C1 -
3UOR
-
?
A:
[27-410]
------------------------------------
K
T
T
V
R
F
W
A
M
G
--
K
---
E
A
-
E
V
V
A
E
L
V
A
D
F
E
K
Q
-
N
P
T
I
H
V
D
V
Q
N
I
P
-
M
T
A
A
H
E
K
L
L
T
A
-
F
A
A
D
-
G
L
P
D
V
C
Q
-
L
G
N
-
T
W
L
P
E
F
A
L
L
D
T
L
E
P
M
Q
P
Y
V
--
A
R
S
K
I
VD
P
A
D
Y
F
P
G
V
W
D
T
N
L
V
D
G
T
L
Y
G
V
P
W
Y
V
D
T
R
L
L
F
Y
R
K
D
L
L
-----
R
------
E
A
G
YSQM
P
K
T
W
---
A
E
M
---------
E
Q
V
M
A
A
---
I
K
R
-----
K
V
GPDR
Y
A
--
I
----
L
M
P
L----
N
E
F
E
Q
----
Q
L
S
F
A
L
Q
Q
D
D
R
-
L
L
R
D
H
-
D
N
--------
Y
G
N
F
R
--
G
A
G
F
R
K
A
L
--------
G
F
Y
D
N
M
Y
Q
Q
--
G
-
W
A
-
P
K
---
V
SET
Q
V
S
N
--
V
W
Y
E
--
F
F
N
G
Y
Y
A
F
Y
L
S
G
P
W
N
V
R
E
F
K
L
R
Q
PPGM
E
----
G
N
W
G
T
A
P
L
P
G
P
N
G
-
L
-
G
---
A
G
I
A
G
G
S
S
L
V
I
F
K
S
S
Q
-----
H
K
D
A
S
W
K
L
I
E
-
Y
-
L
S
Q
P
-
Q
V
Q
A
R
F
H
A
I
I
G
-
D
-
L
P
P
R
R
S
T
W
K
L
P
S
L
A
N
D
A
L
A
H
A
F
G
D
Q
---
L
E
R
V
K
A
T
P
K
V
L
E
W
E
R
I
V
Q
E
M
R
L
V
T
E
R
V
V
R
G
G
--
Q
-
S
----
H
D
A
A
V
Q
E
L
D
Q
-
R
V
D
E
I
L
A
K
R
-----------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
69.86
24%
-38
- C1 -
1URS
1
?
A:
[89-395]
-------------------------------------------------------------------------------------------------------
V
F
G
-
M
P
H
-
D
N
N
G
V
F
A
E
E
G
L
M
A
P
V
P
S
G
V
LN
T
G
L
-
Y
--
A
P
N
----
T
I
D
A
I
K
V
N
G
T
M
Y
S
V
P
V
S
V
Q
V
A
A
I
Y
Y
N
K
-
K
L
-----
V
------
P
Q
P
----
P
Q
T
W
A
--
E
F
V
---------
K
D
A
N
A
H
---
G
F
------
M
-----
Y
D
--
Q
----
A
-------
N
L
Y
-
F
----
D
Y
A
I
I
G
G
Y
G
G
Y
-
V
F
K
D
N
-
N
G
---
T
--
L
D
P
N
N
I
G
LD
T
P
G
A
V
Q
A
Y
--------
T
L
M
R
D
M
V
S
K
--
Y
-
H
W
-
M
T
---
P
---
S
T
N
G
--
S
I
A
K
A
E
F
L
A
G
K
I
G
M
Y
V
S
G
P
W
D
T
A
D
I
E
K
A
---------
K
I
D
F
G
V
T
P
W
P
T
L
P
N
G
K
H
A
T
---
P
F
L
G
V
I
T
A
F
V
N
K
-----
E
S
K
T
Q
A
A
D
W
S
L
V
Q
-
A
-
L
T
S
A
-
Q
A
Q
Q
M
Y
F
R
D
S
Q
-
Q
-
I
P
A
L
L
S
V
Q
R
S
S
A
V
Q
S
S
P
T
F
K
A
F
V
E
---
Q
L
R
Y
A
V
P
M
P
N
I
P
Q
M
Q
A
V
W
-
Q
A
M
S
I
L
Q
N
I
I
A
G
K
--
V
-
S
P
E
Q
G
A
K
D
F
V
Q
N
I
Q
K
-
G
-------------------------------------------------------------------------------------------------------------------------------------------