@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1688: (2015-12-09 )
MKLKHIVLGLALTTLLGVTFSNQEVSASSTSSKVVKVGVMTFSDTEKARWDKIEKLVGDKAKIKFTEFTDYTQPNQATANKDVDINAFQHYNFLENWNKENKKNLIPLEKTYLAPIRIYSEKVKSLKKLKKGATIAIPNDATNGSRALYVLQSAGLIKLNVSGKKVATVANITSNKKDINIQELDASQTPRALKDVDAAIINNTYIEQANLKPSDAIFVEKSDKNSKQWINIIAGRKNWKKQKNAKAIQAILDAYHTDEVKKVIKDTSADIPQW
Atome Classification :
(21 SA)
.........10........20........30........40........50-..--..-..-.-.60-..--.......70........80........90........100..-...-...110.......120----.........130........140.......150.......-160--.-...-.-...170.......180.......190.--..--....200.......210.-.-.....220..-..-.-...230.......240.....-..250.......260--.......-----------.--.270..-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
L
K
H
I
V
L
G
L
A
L
T
T
L
L
G
V
T
FSNQEVSASSTS
S
K
V
V
K
V
G
V
M
TFSDT
E
K
A
R
W
D
-
K
I
--
E
K
-
L
V-G-DK--
A
K
--
I
K
F
T
EFTDYTQPNQATANKDV
D
I
N
A
F
Q
H
Y
N
F
L
E
NWNKE-NKK-NLI-PLEKTY
L
A
P
I
R
I
Y
S
------
E
K
V
K
S
L
K
K
LKK-G
A
T
I
AIPNDATNG
S
R
A
L
Y
V
L
QSA
G
L
I
K
L
-NV---S-G
K
K
-
V
-
A
T
V
A
NITSNKKD
I
N
I
Q
ELDASQT
P
R
A
L
--
K
D
--
V
D
A
A
I
INN
T
Y
I
EQANLKP-S-
D
A
I
F
V
EK-SD-KN-
S
-
K
Q
W
I
N
I
IAGRKN
W
K
K
Q
K
N
A
K
A
-
I
Q
A
I
L
D
A
Y
H
T
D
E
V
----
K
K
V
I
K
DT-----------S--ADIPQW-----
1
PsiBlast_PDB
96.50
56%
-57
- C8 -
4Q5T
4
?
A:
[18-257]
-------------------------------------------
D
S
D
K
E
R
W
D
-
K
I
--
E
E
-
L
L
-
K
K
E
N
--
I
K
--
L
K
F
K
E
F
T
D
Y
S
Q
P
N
K
A
L
K
N
G
E
I
D
I
N
S
F
Q
H
Y
N
F
L
N
N
W
N
K
E
-
N
K
G
-
D
L
V
-
T
V
A
E
T
Y
I
S
P
I
N
L
F
S
G
T
E
NGK
A
K
Y
S
S
A
K
E
I
P
N
-
G
G
Q
I
A
I
P
N
D
A
T
N
E
S
R
A
L
Y
V
L
Q
D
A
G
L
I
K
L
-
N
V
---
S
-
G
D
E
-
L
-
A
T
V
K
N
I
K
S
N
P
K
N
L
D
I
K
E
V
D
A
S
Q
T
A
R
N
L
--
A
S
--
V
D
A
A
V
V
N
N
S
Y
A
V
P
A
K
I
D
F
-
K
-
T
S
L
Y
K
E
K
-
V
N
-
E
G
-
S
-
K
Q
W
I
N
I
I
A
A
Q
K
N
W
K
K
S
K
K
A
A
A
-
I
K
K
L
I
K
A
Y
H
T
D
A
V
----
K
K
V
I
K
K
T
-----------
A
KG
V
D
E
P
V
W
-----
2
PsiBlast_PDB
87.11
41%
-59
- C8 -
4QHQ
2
?
A:
[1-230]
---------------------------------
V
I
K
V
G
T
V
A
G
P
D
S
E
--
V
W
Q
-
V
V
--
Q
K
-
V
A
-
K
-
E
K
--
E
G
LN
V
K
V
I
E
F
N
D
Y
V
Q
P
N
A
A
L
D
S
G
D
L
D
A
N
S
F
Q
H
Q
P
Y
L
D
S
Q
V
K
Q
-
R
G
Y
-
K
I
V
-
S
A
G
L
T
Y
I
S
P
I
G
V
Y
S
------
K
K
F
K
S
L
K
D
L
P
Q
-
G
A
K
L
A
V
P
N
D
P
S
N
E
N
R
A
L
L
L
L
Q
T
Q
G
V
I
K
L
-
K
A
GAG
T
-
G
G
N
-
N
-
A
T
V
L
D
I
A
E
N
P
K
K
L
K
I
S
E
L
D
A
A
Q
L
P
R
V
L
--
S
D
--
V
D
A
A
V
I
N
T
N
Y
A
L
A
A
N
L
Q
P
-
T
K
D
A
I
A
L
E
S
-
L
-----
T
-
S
P
Y
A
N
L
I
A
V
R
---
A
K
D
K
D
Q
P
W
-
V
K
K
L
V
K
A
Y
Q
S
P
E
V
----
K
E
F
I
K
K
Q
-----------
F
--
K
G
S
M
V
A
-----
5
PsiBlast_PDB
84.89
38%
-56
- C8 -
4YAH
1
METQ_ECOLI
X:
[33-255]
----------------------------------
I
K
V
G
V
I
V
G
A
E
Q
Q
V
A
E
V
---
A
--
Q
K
-
V
A
-
K
-
D
K
YG
L
D
--
V
E
L
V
T
F
N
D
Y
V
L
P
N
E
A
L
S
K
G
D
I
D
A
N
A
F
Q
H
K
P
Y
L
D
Q
Q
L
K
D
-
R
G
Y
-
K
L
V
-
A
V
G
N
T
F
V
Y
P
I
A
G
Y
S
------
K
K
I
K
S
L
D
E
L
Q
D
-
G
S
Q
V
A
V
P
N
D
P
T
N
L
G
R
S
L
L
L
L
Q
K
V
G
L
I
K
L
-
K
D
---
G
-
V
G
L
-
L
-
P
T
V
L
D
V
V
E
N
P
K
N
L
K
I
V
E
L
E
A
P
Q
L
P
R
S
L
--
D
D
AQ
I
A
L
A
V
I
N
T
T
Y
A
S
Q
I
G
L
T
P
-
A
K
D
G
I
F
V
E
---
D
-
K
E
-
S
-
P
-
Y
V
N
L
I
V
T
R
E
D
---
N
K
D
A
E
N
-
V
K
K
F
V
Q
A
Y
Q
S
D
E
V
----
Y
E
A
A
N
K
V
-----------
F
--
N
G
G
A
V
K
-----
4
PsiBlast_PDB
84.29
40%
-55
- C8 -
1P99
2
?
A:
[40-274]
---------------------------------
K
V
T
I
G
V
A
S
-
N
D
T
K
--
A
W
E
-
K
V
--
K
E
-
L
A
-
K
K
D
D
--
I
D
--
V
E
I
K
H
F
S
D
Y
N
L
P
N
K
A
L
N
D
G
D
I
D
M
N
A
F
Q
H
F
A
F
L
D
Q
Y
K
K
A
-
H
K
G
-
T
K
I
S
A
L
S
T
T
V
L
A
P
L
G
I
Y
S
------
D
K
I
K
D
V
K
K
V
K
D
-
G
A
K
V
V
I
P
N
D
V
S
N
Q
A
R
A
L
K
L
L
E
A
A
G
L
I
K
L
-
K
K
---
D
-
F
G
L
-
A
-
G
T
V
K
D
I
T
S
N
P
K
H
L
K
I
T
A
V
D
A
Q
Q
T
A
R
A
L
--
S
D
--
V
D
I
A
V
I
N
N
G
V
A
T
K
A
G
K
D
P
K
N
-
D
P
I
F
L
E
K
-
S
N
-
S
D
-
A
V
K
P
Y
I
N
I
V
A
V
N
---
D
K
D
L
D
N
K
T
-
Y
A
K
I
V
E
L
Y
H
S
K
E
A
----
Q
K
A
L
Q
E
D
-----------
V
--
K
D
G
E
K
P
-----
42
Fugue
83.73
40%
-56
- C8 -
1P99
2
?
A:
[40-294]
---------------------------------
K
V
T
I
G
V
---
A
S
N
D
T
K
A
W
E
-
K
V
--
K
E
-
L
A
-
K
-
K
D
D-
I
D
--
V
E
I
K
H
F
S
D
Y
N
L
P
N
K
A
L
N
D
G
D
I
D
M
N
A
F
Q
H
F
A
F
L
D
Q
Y
K
K
A
-
H
K
G
T
K
I
S
-
A
L
S
T
T
V
L
A
P
L
G
I
Y
S
------
D
K
I
K
D
V
K
K
V
K
D
-
G
A
K
V
V
I
P
N
D
V
S
N
Q
A
R
A
L
K
L
L
E
A
A
G
L
I
K
L
-
K
K
---
D
-
F
G
L
-
A
-
G
T
V
K
D
I
T
S
N
P
K
H
L
K
I
T
A
V
D
A
Q
Q
T
A
R
A
L
--
S
D
--
V
D
I
A
V
I
N
N
G
V
A
T
K
A
G
K
D
P
K
N
-
D
P
I
F
L
E
K
S
N
S
-
D
A
-
V
-
K
P
Y
I
N
I
V
A
V
N
---
D
K
D
L
D
N
K
T
-
Y
A
K
I
V
E
L
Y
H
S
K
E
A
----
Q
K
A
L
Q
E
D
VKDG
E
K
P
V
N
L
S
K
--
D
E
I
K
A
I
E
T
S
L
A
53
HHSearch
83.11
40%
-57
- C8 -
1P99
2
?
A:
[40-272]
---------------------------------
K
V
T
I
G
V
A
S
N
D
--
T
K
-
A
W
E
-
K
V
--
K
E
-
L
A
-
K
K
D
D
--
I
D
--
V
E
I
K
H
F
S
D
Y
N
L
P
N
K
A
L
N
D
G
D
I
D
M
N
A
F
Q
H
F
A
F
L
D
Q
Y
K
K
A
H
K
G
T
-
K
I
S
-
A
L
S
T
T
V
L
A
P
L
G
I
Y
S
------
D
K
I
K
D
V
K
K
V
-
K
D
G
A
K
V
V
I
P
N
D
V
S
N
Q
A
R
A
L
K
L
L
E
A
A
G
L
I
K
L
-
K
K
---
D
-
F
G
L
-
A
-
G
T
V
K
D
I
T
S
N
P
K
H
L
K
I
T
A
V
D
A
Q
Q
T
A
R
A
L
--
S
D
--
V
D
I
A
V
I
N
N
G
V
A
T
K
A
G
K
D
P
K
N
-
D
P
I
F
L
E
K
-
S
N
S
D
A
-
V
-
K
P
Y
I
N
I
V
A
V
N
D
K
D
-
L
D
N
--
K
T
-
Y
A
K
I
V
E
L
Y
H
S
K
E
A
----
Q
K
A
L
Q
E
D
-----------
V
--
K
D
G
E
K
P
-----
56
HHSearch
81.47
28%
-59
- C8 -
1XS5
1
TPN32_TREPA
A:
[2-231]
-------------------------------
D
E
T
V
G
V
G
V
L
S
E
P
--
H
A
R
L
L
E
-
I
A
--
K
E
-
E
V
-
K
K
Q
H
--
I
E
--
L
R
I
V
E
F
T
N
Y
V
A
L
N
E
A
V
M
R
G
D
I
L
M
N
F
F
Q
H
V
P
H
M
Q
Q
F
N
Q
E
-
H
N
G
-
D
L
V
-
S
V
G
N
V
H
V
E
P
L
A
L
Y
S
------
R
T
Y
R
H
V
S
D
F
P
A
-
G
A
V
I
A
I
P
N
D
S
S
N
E
A
R
A
L
R
L
L
E
A
A
G
F
I
R
M
-
R
A
---
G
-
S
G
L
-
F
-
A
T
V
E
D
V
Q
Q
N
V
R
N
V
V
L
Q
E
V
E
S
A
L
L
P
R
V
F
--
D
Q
--
V
D
G
A
V
I
N
G
N
Y
A
I
M
A
G
L
S
A
-
R
R
D
G
L
A
V
E
P
-----
D
-
A
-
S
A
Y
A
N
V
L
V
V
K
R
G
N
-
E
--
A
D
A
R
-
V
Q
A
V
L
R
A
L
C
G
G
R
V
----
R
T
Y
L
K
E
R
-----------
Y
--
K
G
G
E
V
A
-----
58
HHSearch
81.11
31%
-47
* C8 *
3GXA
7
?
A:
[23-251]
--------------------------------
K
E
I
V
F
G
T
T
V
G
D
--
F
G
D
M
V
K
E
Q
I
--
Q
P
-
E
L
-
E
K
K
G
--
Y
T
--
V
K
L
V
E
F
T
D
Y
V
R
P
N
L
A
L
A
E
G
E
L
D
I
N
V
F
Q
H
K
P
Y
L
D
D
F
K
K
E
-
H
N
L
-
D
I
T
-
E
V
F
Q
V
P
T
A
P
L
G
L
Y
P
------
G
K
L
K
S
L
E
E
V
K
D
-
G
S
T
V
S
A
P
N
D
P
S
N
F
A
R
V
L
V
M
L
D
E
L
G
W
I
K
L
-
K
D
---
G
-
I
N
P
L
T
-
A
S
K
A
D
I
A
E
N
L
K
N
I
K
I
V
E
L
E
A
A
Q
L
P
R
S
R
--
A
D
--
V
D
F
A
V
V
N
G
N
Y
A
I
S
S
G
M
K
L
-
T
--
E
A
L
F
Q
E
-
P
-----
S
-
F
A
Y
V
N
W
S
A
V
K
T
A
D
-
K
--
D
S
Q
W
-
L
K
D
V
T
E
A
Y
N
S
D
A
F
----
K
A
Y
A
H
K
R
-----------
F
--
E
G
Y
K
S
P
-----
57
HHSearch
78.39
35%
-56
- C8 -
3TQW
1
?
A:
[4-240]
---------------------------------
M
V
R
V
G
T
I
A
G
P
--
E
T
Q
L
M
E
-
V
A
--
K
Q
-
V
A
L
N
R
Y
G
--
L
H
--
V
N
I
I
T
F
S
D
Y
N
T
P
N
E
A
L
A
D
G
S
V
D
A
N
M
F
Q
H
L
P
Y
L
K
A
Q
I
E
M
-
R
G
Y
-
K
I
V
-
S
I
G
K
T
F
V
Y
P
M
G
L
Y
S
------
K
K
I
T
A
L
T
Q
L
K
T
-
G
A
K
I
A
V
P
S
D
P
S
N
E
A
R
A
L
L
L
L
E
K
A
Q
L
I
Q
L
-
K
T
---
H
---
I
-
N
-
A
T
P
M
D
I
A
S
N
P
K
K
L
K
I
V
E
L
D
A
A
Q
L
S
R
S
L
--
G
D
--
V
D
L
A
A
I
N
T
N
Y
A
I
P
A
G
L
S
P
-
S
R
D
A
L
L
T
E
G
-
P
-----
N
-
S
P
Y
A
N
V
V
A
V
R
E
D
D
-
K
--
N
D
P
R
-
L
K
Q
L
V
S
A
L
H
S
P
A
V
----
L
S
A
A
K
K
I
FG---------
D
--
G
A
I
P
A
------
60
HHSearch
77.72
31%
-46
- C8 -
3IR1
6
?
A:
[2-229]
---------------------------------
E
I
V
F
G
T
T
V
G
D
F
-
G
D
M
V
K
E
-
Q
I
--
Q
P
-
E
L
-
E
K
K
G
--
Y
T
--
V
K
L
V
E
F
T
D
Y
V
R
P
N
L
A
L
A
E
G
E
L
D
I
N
V
F
Q
H
K
P
Y
L
D
D
F
K
K
E
-
H
N
L
-
D
I
T
-
E
V
F
Q
V
P
T
A
P
L
G
L
Y
P
------
G
K
L
K
S
L
E
E
V
K
D
-
G
S
T
V
S
A
P
N
D
P
S
N
F
A
R
V
L
V
M
L
D
E
L
G
W
I
K
L
-
K
D
---
G
-
I
N
P
L
T
-
A
S
K
A
D
I
A
E
N
L
K
N
I
K
I
V
E
L
E
A
A
Q
L
P
R
S
R
--
A
D
--
V
D
F
A
V
V
N
G
N
Y
A
I
S
S
G
M
K
L
-
T
--
E
A
L
F
Q
E
-
P
-----
S
-
F
A
Y
V
N
W
S
A
V
K
T
A
D
-
K
--
D
S
Q
W
-
L
K
D
V
T
E
A
Y
N
S
D
A
F
----
K
A
Y
A
H
K
R
-----------
F
--
E
G
Y
K
S
P
-----
52
HHSearch
77.29
31%
-52
- C8 -
3UP9
6
?
A:
[5-245]
------------------------------
D
V
V
T
L
T
V
G
A
T
P
S
P
--
H
A
K
I
L
T
-
Y
I
--
N
D
N
L
A
-
A
D
A
G
--
I
K
--
L
D
I
V
E
Y
T
D
Y
V
Q
P
N
T
A
L
N
D
G
D
L
D
A
N
F
Y
Q
T
V
P
Y
L
E
N
A
E
K
Q
-
F
G
Y
-
N
F
E
-
A
G
E
G
I
H
L
E
P
L
G
V
F
S
------
N
K
H
K
S
L
D
E
L
P
D
-
G
G
T
I
G
I
I
S
D
T
A
N
Q
S
R
A
L
E
L
L
A
T
Q
G
L
V
S
I
-
P
E
---
G
-----
D
-
V
N
I
N
T
V
T
-
K
L
K
N
F
D
F
R
E
V
E
G
P
Q
L
V
R
S
L
--
D
D
--
F
D
Y
A
V
I
N
G
N
F
A
Q
E
G
G
K
T
I
S
G
-
D
A
L
V
V
E
S
-
P
---
V
-
D
-
N
P
A
V
N
V
L
V
W
K
G
D
S
-
K
--
K
V
D
A
-
I
A
K
L
E
K
L
L
H
S
D
E
V
----
K
Q
Y
I
E
K
T
W
SD--------
G
--
S
V
I
P
A
F
-----
11
PsiBlast_PDB
77.15
29%
-60
- C8 -
1XS5
1
TPN32_TREPA
A:
[5-230]
------------------------------------
V
G
V
G
V
L
S
E
P
H
-
A
R
L
L
-
E
I
A
K
E
E
-
V
K
-
K
-
Q
H
--
I
E
--
L
R
I
V
E
F
T
N
Y
V
A
L
N
E
A
V
M
R
G
D
I
L
M
N
F
F
Q
H
V
P
H
M
Q
Q
F
N
Q
E
-
H
N
G
-
D
L
V
-
S
V
G
N
V
H
V
E
P
L
A
L
Y
S
------
R
T
Y
R
H
V
S
D
F
P
A
-
G
A
V
I
A
I
P
N
D
S
S
N
E
A
R
A
L
R
L
L
E
A
A
G
F
I
R
M
-
R
A
---
G
-
S
G
L
-
F
-
A
T
V
E
D
V
Q
Q
N
V
R
N
V
V
L
Q
E
V
E
S
A
L
L
P
R
V
F
--
D
Q
--
V
D
G
A
V
I
N
G
N
Y
A
I
M
A
G
L
S
A
R
R
-
D
G
L
A
V
E
-----
P
D
-
A
-
S
A
Y
A
N
V
L
V
----
V
K
R
G
N
E
A
D
A
R
V
Q
A
V
L
R
A
L
C
G
G
R
V
----
R
T
Y
L
K
E
R
-----------
Y
--
K
G
G
E
V
A
-----
6
PsiBlast_PDB
75.83
41%
-55
- C8 -
3K2D
1
?
A:
[36-228]
------------------------------------------------------------------------
V
E
L
V
T
F
T
D
Y
V
T
P
N
A
A
L
D
D
G
S
I
D
M
N
A
F
Q
H
K
P
Y
L
D
R
Q
V
E
D
-
R
D
Y
-
K
L
T
-
I
A
G
N
T
F
V
Y
P
I
A
G
Y
S
------
K
Q
V
K
S
V
A
A
L
A
D
-
G
V
R
I
A
V
P
N
D
P
T
N
L
G
R
S
L
L
L
L
E
Q
Q
G
L
I
K
L
-
R
P
---
E
-
V
G
L
-
L
-
A
T
V
R
D
I
V
E
N
P
K
N
I
T
I
M
E
L
D
A
A
Q
L
P
R
S
L
--
D
D
--
V
A
L
S
I
I
N
T
T
Y
A
S
S
I
N
L
T
P
-
E
K
D
G
V
F
V
E
---
D
-
K
E
-
S
-
P
-
Y
V
N
L
I
V
A
R
Q
D
N
V
Q
N
E
N
----
V
Q
N
F
V
K
A
Y
Q
T
E
E
V
----
Y
T
A
A
K
E
I
-----------
F
--
K
----------
3
PsiBlast_PDB
75.68
40%
-52
- C8 -
4K3F
9
?
A:
[32-230]
------------------------------------------------------------------------
L
K
I
K
E
F
T
D
Y
V
Q
P
N
V
Q
V
S
E
K
R
L
D
A
N
F
F
Q
H
Q
P
Y
L
D
E
F
N
K
A
-
K
G
T
-
D
L
V
-
A
V
T
G
V
H
I
E
P
L
G
A
Y
S
------
S
K
Y
K
K
L
D
E
L
P
S
-
G
A
T
V
V
I
P
N
D
A
T
N
G
G
R
A
L
L
L
L
D
K
A
G
V
I
K
L
-
K
D
---
N
-
K
S
I
-
T
-
A
T
P
K
D
I
V
D
N
P
K
N
I
K
I
R
E
L
E
A
A
T
L
P
R
V
L
--
T
Q
--
V
D
M
A
L
I
N
T
N
Y
A
L
E
A
K
L
N
P
-
T
K
D
A
L
A
I
E
G
-
S
D
------
S
P
Y
V
N
I
L
V
A
R
P
D
---
N
K
D
S
D
A
-
M
Q
K
L
A
K
A
L
H
S
A
E
I
----
K
Q
F
I
Q
E
K
-----------
Y
--
K
G
A
V
V
P
-----
21
PsiBlast_CBE
75.17
41%
-54
- C8 -
3K2D
1
?
B:
[36-228]
------------------------------------------------------------------------
V
E
L
V
T
F
T
D
Y
V
T
P
N
A
A
L
D
D
G
S
I
D
M
N
A
F
Q
H
K
P
Y
L
D
R
Q
V
E
D
-
R
D
Y
-
K
L
T
-
I
A
G
N
T
F
V
Y
P
I
A
G
Y
S
------
K
Q
V
K
S
V
A
A
L
A
D
-
G
V
R
I
A
V
P
N
D
P
T
N
L
G
R
S
L
L
L
L
E
Q
Q
G
L
I
K
L
-
R
P
---
E
-
V
G
L
-
L
-
A
T
V
R
D
I
V
E
N
P
K
N
I
T
I
M
E
L
D
A
A
Q
L
P
R
S
L
--
D
D
--
V
A
L
S
I
I
N
T
T
Y
A
S
S
I
N
L
T
P
-
E
K
D
G
V
F
V
E
---
D
-
K
E
-
S
-
P
-
Y
V
N
L
I
V
A
R
Q
D
N
V
Q
N
E
N
----
V
Q
N
F
V
K
A
Y
Q
T
E
E
V
----
Y
T
A
A
K
E
I
-----------
F
--
K
----------
14
PsiBlast_PDB
73.85
36%
-57
- C8 -
4GOT
1
METQ_BACSU
A:
[35-237]
------------------------------------------------------------------------
L
K
V
K
V
L
S
D
Y
K
M
Y
N
K
A
L
A
D
K
E
V
D
A
N
Y
F
Q
H
I
P
Y
L
E
Q
E
M
K
E
-
N
T
D
Y
K
L
V
-
N
A
G
A
V
H
L
E
P
F
G
I
Y
S
------
K
T
Y
K
S
L
K
D
L
P
D
-
G
A
T
I
I
L
T
N
N
V
A
E
Q
G
R
M
L
A
M
L
E
N
A
G
L
I
T
L
-
D
S
---
K
-
V
E
T
-
V
D
A
T
L
K
D
I
K
K
N
P
K
N
L
E
F
K
K
V
A
P
E
L
T
A
K
A
Y
E
N
K
E
--
G
D
A
V
F
I
N
V
N
Y
A
I
Q
N
K
L
N
P
K
K
-
D
A
I
E
V
E
S
-
T
K
-
N
N
-
P
---
Y
A
N
I
I
A
V
R
K
G
---
E
E
D
S
A
K
-
I
K
A
L
M
E
V
L
H
S
K
K
I
----
K
D
F
I
E
K
K
-----------
Y
--
D
G
A
V
L
P
-----
8
PsiBlast_PDB
71.71
35%
-37
- C8 -
4IB2
7
?
A:
[39-250]
---------------------------------------------------------------------
Q
--
L
E
V
T
V
F
D
D
Y
V
Q
P
N
E
V
V
E
S
G
E
F
D
A
N
Y
F
Q
H
V
P
Y
L
E
S
F
N
E
E
-
K
G
T
-
H
L
V
-
D
A
G
D
I
H
Y
E
P
F
G
I
Y
P
------
G
T
K
K
S
L
D
E
I
S
E
-
G
D
K
I
A
V
P
N
D
T
T
N
E
A
R
A
L
L
L
L
Q
D
N
G
I
I
T
L
-
K
D
---
G
-
A
G
L
-
N
-
A
T
V
N
D
I
E
E
N
P
Y
N
V
E
I
V
E
L
E
A
A
Q
V
A
R
V
T
--
G
E
--
T
A
Y
V
V
L
N
G
N
Y
A
L
E
A
G
Y
S
V
-
A
K
D
A
L
A
Y
E
K
-
S
D
-
S
E
A
A
-
K
T
Y
V
N
I
I
A
V
K
E
G
N
E
K
E
E
K
----
I
Q
A
L
V
K
A
L
K
S
D
E
I
----
K
E
Y
I
E
K
T
YD---------
G
--
A
V
I
P
F
E
-----
10
PsiBlast_PDB
71.61
35%
-40
- C8 -
3IR1
5
?
A:
[31-223]
------------------------------------------------------------------------
V
K
L
V
E
F
T
D
Y
V
R
P
N
L
A
L
A
E
G
E
L
D
I
N
V
F
Q
H
K
P
Y
L
D
D
F
K
K
E
-
H
N
L
-
D
I
T
-
E
V
F
Q
V
P
T
A
P
L
G
L
Y
P
------
G
K
L
K
S
L
E
E
V
K
D
-
G
S
T
V
S
A
P
N
D
P
S
N
F
A
R
V
L
V
M
L
D
E
L
G
W
I
K
L
K
D
G
---
I
-
N
P
L
-
T
-
A
S
K
A
D
I
A
E
N
L
K
N
I
K
I
V
E
L
E
A
A
Q
L
P
R
S
R
--
A
D
--
V
D
F
A
V
V
N
G
N
Y
A
I
S
S
G
M
K
L
-
T
-
E
A
L
F
Q
E
P
-------
S
-
F
A
Y
V
N
W
S
A
V
K
---
T
A
D
K
D
S
Q
W
-
L
K
D
V
T
E
A
Y
N
S
D
A
F
----
K
A
Y
A
H
K
R
-----------
F
--
E
G
Y
K
S
P
-----
23
PsiBlast_CBE
71.38
35%
-39
- C8 -
3GXA
7
?
F:
[53-245]
------------------------------------------------------------------------
V
K
L
V
E
F
T
D
Y
V
R
P
N
L
A
L
A
E
G
E
L
D
I
N
V
F
Q
H
K
P
Y
L
D
D
F
K
K
E
-
H
N
L
-
D
I
T
-
E
V
F
Q
V
P
T
A
P
L
G
L
Y
P
------
G
K
L
K
S
L
E
E
V
K
D
-
G
S
T
V
S
A
P
N
D
P
S
N
F
A
R
V
L
V
M
L
D
E
L
G
W
I
K
L
-
K
D
---
G
I
N
P
L
-
T
-
A
S
K
A
D
I
A
E
N
L
K
N
I
K
I
V
E
L
E
A
A
Q
L
P
R
S
R
--
A
D
--
V
D
F
A
V
V
N
G
N
Y
A
I
S
S
G
M
K
L
-
T
-
E
A
L
F
Q
E
P
-------
S
-
F
A
Y
V
N
W
S
A
V
K
---
T
A
D
K
D
S
Q
W
-
L
K
D
V
T
E
A
Y
N
S
D
A
F
----
K
A
Y
A
H
K
R
-----------
F
--
E
G
Y
K
S
P
-----
7
PsiBlast_PDB
71.35
34%
-40
- C8 -
3TQW
1
?
A:
[4-235]
---------------------------------
M
V
R
V
G
T
I
A
G
P
E
T
Q
L
M
E
V
A
-
K
Q
--
V
A
-
L
N
-
R
-
Y
G
--
L
H
--
V
N
I
I
T
F
S
D
Y
N
T
P
N
E
A
L
A
D
G
S
V
D
A
N
M
F
Q
H
L
P
Y
L
K
A
Q
I
E
M
-
R
G
Y
-
K
I
V
-
S
I
G
K
T
F
V
Y
P
M
G
L
Y
S
------
K
K
I
T
A
L
T
Q
L
K
T
-
G
A
K
I
A
V
P
S
D
P
S
N
E
A
R
A
L
L
L
L
E
K
A
Q
L
I
Q
L
-
K
T
---
H
---
I
-
N
-
A
T
P
M
D
I
A
S
N
P
K
K
L
K
I
V
E
L
D
A
A
Q
L
S
R
S
L
--
G
D
--
V
D
L
A
A
I
N
T
N
Y
A
I
P
A
G
L
S
P
-
S
R
D
A
L
L
T
E
G
-
P
N
------
S
P
Y
A
N
V
V
A
V
R
E
D
---
D
K
N
D
P
R
-
L
K
Q
L
V
S
A
L
H
S
P
A
V
L
S
A
A
K
K
I
F
G
D
G
-----------
A
--
I
P
A
--------
22
PsiBlast_CBE
71.02
35%
-38
- C8 -
4IB2
8
?
B:
[39-250]
---------------------------------------------------------------------
Q
--
L
E
V
T
V
F
D
D
Y
V
Q
P
N
E
V
V
E
S
G
E
F
D
A
N
Y
F
Q
H
V
P
Y
L
E
S
F
N
E
E
-
K
G
T
-
H
L
V
-
D
A
G
D
I
H
Y
E
P
F
G
I
Y
P
------
G
T
K
K
S
L
D
E
I
S
E
-
G
D
K
I
A
V
P
N
D
T
T
N
E
A
R
A
L
L
L
L
Q
D
N
G
I
I
T
L
-
K
D
---
G
-
A
G
L
-
N
-
A
T
V
N
D
I
E
E
N
P
Y
N
V
E
I
V
E
L
E
A
A
Q
V
A
R
V
T
--
G
E
--
T
A
Y
V
V
L
N
G
N
Y
A
L
E
A
G
Y
S
V
-
A
K
D
A
L
A
Y
E
K
-
S
D
-
S
E
A
A
-
K
T
Y
V
N
I
I
A
V
K
E
G
N
E
K
E
E
K
----
I
Q
A
L
V
K
A
L
K
S
D
E
I
----
K
E
Y
I
E
K
T
YD---------
G
--
A
V
I
P
F
E
-----