@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1722: (2015-12-10 )
MAIKAVFFDIDGTLLNDRKNVQKSTIKAIRNLKDQGILVGLATGRGPSFVQPFLENLGLDFAVTYNGQYIYSRSEIIYTNQLSKTTVYRLIRYAGARRREISLGTASGLLGSGIIGLGTSRLGQIVSSLVPRKWAKAIERSFKHFIRRIKPQNIDSLMIILREPIYQVVLVATEGESERIQKQFPRVKLTRSSPYSMDVISEEQSKVKGIERVGQRYGFDLSEVIAFGDSDNDIEMLSQVGIGVAMGNASQQVKENARYTTADNNDDGISKALAHYGLIQFEIEKTFSSRDENFNKVKSFHLLMDGETIETPRLYDSKEAGFRSDFKVEEIVEFLYAASQGNQKVFDQSIRNLHLAIDKARDKVISKDHPETPLVGEVDALTDLLYLTYGSFVLMGVDPKPLFDTVHEANMGKIFPDGKAHFDPVTHKILKPDDWEEHFAPEPSIRRELDSQIQKSLNRK
Atome Classification :
(20 SA)
.........10.....-..-.-20........30........40........50....----.--..-.----60---..-.......70-...--...-...80-......-..90-------........100........110--.---........120----.----.....--..130.-.---.....140..-.....150.......160-.--.....-..170-...-----.-----...---180--..---..----.-.------...--190.......200.......210.......220.......230.......240.......250.......--260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
I
K
A
V
F
F
DIDGTLLN-
D
R
-
K
-
N
V
Q
K
S
T
I
K
A
I
R
NLKDQ
G
I
L
V
G
LATGRG
P
S
F
V
Q
P
F
L
E
----N--LG-L----
D
----
F
A
-
V
T
YN
G
Q
Y
I
--
Y
SR--
S
E
I
-
I
Y
TNQ-L
S
K
T
T
V
-
Y
R
L
I
-------
R
Y
AGAR
R
R
E
-
I
SLGTASGLL----G---S
G
I
I
GL
G
T
S
R
-----
L
----
G
Q
I
V
S
--
S
L
V
P
R
K
-
W
---
A
K
A
I
E
R
S
F
K
H
-
F
I
R
RIKPQ
N
I
D
S
L
M
I
I
-
L
-R--EP
I
Y
Q
-
V
V
L
V
A-TEG-----
E
-----
S
E
R
---
I
----
Q
K
---QF----P-
R
------
V
K
L
--TRSSPYSM
D
V
I
S
E
E
Q
S
K
V
K
G
I
E
R
V
G
Q
RYGF
D
L
S
E
V
I
AFGDSD
N
D
I
E
M
L
S
QVG
I
G
V
AMG
N
A
S
Q
Q
V
K
ENA
R
Y
--TTADNND
D
G
I
S
K
A
L
A
HYG
L
I
Q
F
E
I
E
K
TFSSRDE
N
F
N
K
V
K
S
F
H
L
L
MDGETIETPRLYDSKEAGFRSDF
K
V
E
E
I
V
E
F
L
Y
AASQGN
Q
K
V
F
D
Q
S
I
R
N
L
H
L
A
I
D
K
A
R
D
KVISKDHPETPLVG
E
V
D
A
L
T
D
L
L
Y
L
TYG
S
F
V
L
MGV
D
P
K
P
L
F
D
T
V
H
EANMGKIFPDGKAHFD
P
V
T
H
KILKPD
D
W
E
EHFAP
E
P
S
I
R
R
E
L
D
S
Q
I
Q
K
S
LNRK
2
PsiBlast_PDB
93.37
33%
-82
- C3 -
2QYH
5
?
A:
[4-257]
---
K
I
V
F
F
D
I
D
G
T
L
L
D
-
E
Q
-
K
-
Q
L
P
L
S
T
I
E
A
V
R
R
L
K
Q
S
G
V
Y
V
A
I
A
T
G
R
A
P
F
M
F
E
H
V
R
K
----
Q
--
L
G
-
I
----
D
----
S
F
-
V
S
F
N
G
Q
Y
V
--
V
F
E
--
G
N
V
-
L
Y
K
Q
P
-
L
R
R
E
K
V
-
R
A
L
T
-------
E
E
A
H
K
N
G
H
P
-
L
V
F
M
D
A
E
K
M
R
----
A
---
S
----
I
G
D
H
---------------------
P
H
I
-
H
---
V
S
M
A
S
L
K
F
A
H
--------
P
P
V
D
P
L
Y
Y
E
-
N
-
K
--
D
-
I
Y
Q
-
A
L
L
F
C
-
R
A
E
-----
E
-----
E
E
P
---
Y
----
V
R
---
N
Y
----
P
-
E
------
F
R
F
--
V
R
W
H
D
V
S
T
D
V
L
P
A
G
G
S
K
A
E
G
I
R
M
M
I
E
K
L
G
I
D
K
K
D
V
Y
A
F
G
D
G
L
N
D
I
E
M
L
S
F
V
G
T
G
V
A
M
G
N
A
H
E
E
V
K
R
V
A
D
F
--
V
T
K
P
V
D
K
E
G
I
W
Y
G
L
K
Q
L
Q
L
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
92.28
30%
-77
- C3 -
1YMQ
3
?
A:
[3-261]
---
K
A
L
F
F
D
I
D
G
T
L
V
S
F
E
T
-
H
-
R
I
P
S
S
T
I
E
A
L
E
A
A
H
A
K
G
L
K
I
F
I
A
T
G
R
P
K
A
I
I
N
N
L
S
E
L
Q
D
R
N
--
L
--
I
----
D
----
G
Y
-
I
T
M
N
G
A
Y
C
--
F
V
G
--
E
E
V
-
I
Y
K
S
A
-
I
P
Q
E
E
V
-
K
A
M
A
-------
A
F
C
E
K
K
-----------------------
G
V
P
C
I
F
V
E
E
-----
H
----
N
--
I
S
--
V
C
Q
P
N
E
-
M
---
V
K
K
I
F
Y
D
F
L
H
--
V
N
V
I
P
T
V
S
F
E
E
A
S
-----
N
--
K
E
V
I
Q
-
M
T
P
F
I
-
T
E
E
-----
E
-----
E
K
E
---
V
----
L
P
---
S
I
----
P
-
T
------
C
E
I
--
G
R
W
Y
P
A
F
A
D
V
T
A
K
G
D
T
K
Q
K
G
I
D
E
I
I
R
H
F
G
I
K
L
E
E
T
M
S
F
G
D
G
G
N
D
I
S
M
L
R
H
A
A
I
G
V
A
M
G
Q
A
K
E
D
V
K
A
A
A
D
Y
--
V
T
A
P
I
D
E
D
G
I
S
K
A
M
K
H
F
G
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
91.56
30%
-73
- C3 -
2RBK
2
?
A:
[3-261]
---
K
A
L
F
F
D
I
D
G
T
L
V
S
F
E
T
-
H
-
R
I
P
S
S
T
I
E
A
L
E
A
A
H
A
K
G
L
K
I
F
I
A
T
G
R
P
K
A
I
I
N
N
L
S
E
L
Q
D
R
N
--
L
--
I
----
D
----
G
Y
-
I
T
M
N
G
A
Y
C
--
F
V
G
--
E
E
V
-
I
Y
K
S
A
-
I
P
Q
E
E
V
-
K
A
M
A
-------
A
F
C
E
K
K
-----------------------
G
V
P
C
I
F
V
E
E
-----
H
----
N
--
I
S
--
V
C
Q
P
N
E
-
M
---
V
K
K
I
F
Y
D
F
L
H
--
V
N
V
I
P
T
V
S
F
E
E
A
S
-----
N
--
K
E
V
I
Q
-
M
T
P
F
I
-
T
E
E
-----
E
-----
E
K
E
---
V
----
L
P
---
S
I
----
P
-
T
------
C
E
I
--
G
R
W
Y
P
A
F
A
D
V
T
A
K
G
D
T
K
Q
K
G
I
D
E
I
I
R
H
F
G
I
K
L
E
E
T
M
S
F
G
D
G
G
N
D
I
S
M
L
R
H
A
A
I
G
V
A
M
G
Q
A
K
E
D
V
K
A
A
A
D
Y
--
V
T
A
P
I
D
E
D
G
I
S
K
A
M
K
H
F
G
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
91.14
30%
-73
- C3 -
2RB5
2
?
A:
[3-261]
---
K
A
L
F
F
D
I
D
G
T
L
V
S
F
E
T
-
H
-
R
I
P
S
S
T
I
E
A
L
E
A
A
H
A
K
G
L
K
I
F
I
A
T
G
R
P
K
A
I
I
N
N
L
S
E
L
Q
D
R
N
--
L
--
I
----
D
----
G
Y
-
I
T
M
N
G
A
Y
C
--
F
V
G
--
E
E
V
-
I
Y
K
S
A
-
I
P
Q
E
E
V
-
K
A
M
A
-------
A
F
C
E
K
K
-----------------------
G
V
P
C
I
F
V
E
E
-----
H
----
N
--
I
S
--
V
C
Q
P
N
E
-
M
---
V
K
K
I
F
Y
D
F
L
H
--
V
N
V
I
P
T
V
S
F
E
E
A
S
-----
N
--
K
E
V
I
Q
-
M
T
P
F
I
-
T
E
E
-----
E
-----
E
K
E
---
V
----
L
P
---
S
I
----
P
-
T
------
C
E
I
--
G
R
W
Y
P
A
F
A
D
V
T
A
K
G
D
T
K
Q
K
G
I
D
E
I
I
R
H
F
G
I
K
L
E
E
T
M
S
F
G
D
G
G
N
D
I
S
M
L
R
H
A
A
I
G
V
A
M
G
Q
A
K
E
D
V
K
A
A
A
D
Y
--
V
T
A
P
I
D
E
D
G
I
S
K
A
M
K
H
F
G
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
91.11
29%
-75
- C3 -
2RAR
2
?
A:
[3-261]
---
K
A
L
F
F
D
I
A
G
T
L
V
S
F
E
T
-
H
-
R
I
P
S
S
T
I
E
A
L
E
A
A
H
A
K
G
L
K
I
F
I
A
T
G
R
P
K
A
I
I
N
N
L
S
E
L
Q
D
R
N
--
L
--
I
----
D
----
G
Y
-
I
T
M
N
G
A
Y
C
--
F
V
G
--
E
E
V
-
I
Y
K
S
A
-
I
P
Q
E
E
V
-
K
A
M
A
-------
A
F
C
E
K
K
-----------------------
G
V
P
C
I
F
V
E
E
-----
H
----
N
--
I
S
--
V
C
Q
P
N
E
-
M
---
V
K
K
I
F
Y
D
F
L
H
--
V
N
V
I
P
T
V
S
F
E
E
A
S
-----
N
--
K
E
V
I
Q
-
M
T
P
F
I
-
T
E
E
-----
E
-----
E
K
E
---
V
----
L
P
---
S
I
----
P
-
T
------
C
E
I
--
G
R
W
Y
P
A
F
A
D
V
T
A
K
G
D
T
K
Q
K
G
I
D
E
I
I
R
H
F
G
I
K
L
E
E
T
M
S
F
G
D
G
G
N
D
I
S
M
L
R
H
A
A
I
G
V
A
M
G
Q
A
K
E
D
V
K
A
A
A
D
Y
--
V
T
A
P
I
D
E
D
G
I
S
K
A
M
K
H
F
G
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
90.81
29%
-74
- C3 -
2RAV
2
?
A:
[3-261]
---
K
A
L
F
F
D
I
A
G
T
L
V
S
F
E
T
-
H
-
R
I
P
S
S
T
I
E
A
L
E
A
A
H
A
K
G
L
K
I
F
I
A
T
G
R
P
K
A
I
I
N
N
L
S
E
L
Q
D
R
N
--
L
--
I
----
D
----
G
Y
-
I
T
M
N
G
A
Y
C
--
F
V
G
--
E
E
V
-
I
Y
K
S
A
-
I
P
Q
E
E
V
-
K
A
M
A
-------
A
F
C
E
K
K
-----------------------
G
V
P
C
I
F
V
E
E
-----
H
----
N
--
I
S
--
V
C
Q
P
N
E
-
M
---
V
K
K
I
F
Y
D
F
L
H
--
V
N
V
I
P
T
V
S
F
E
E
A
S
-----
N
--
K
E
V
I
Q
-
M
T
P
F
I
-
T
E
E
-----
E
-----
E
K
E
---
V
----
L
P
---
S
I
----
P
-
T
------
C
E
I
--
G
R
W
Y
P
A
F
A
D
V
T
A
K
G
D
T
K
Q
K
G
I
D
E
I
I
R
H
F
G
I
K
L
E
E
T
M
S
F
G
D
G
G
N
D
I
S
M
L
R
H
A
A
I
G
V
A
M
G
Q
A
K
E
D
V
K
A
A
A
D
Y
--
V
T
A
P
I
D
E
D
G
I
S
K
A
M
K
H
F
G
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
120
HHSearch
90.02
31%
-70
* C3 *
2RBK
2
?
A:
[1-260]
-
M
T
K
A
L
F
F
D
I
D
G
T
L
V
S
-
F
E
T
H
-
R
I
P
S
S
T
I
E
A
L
E
A
A
H
A
K
G
L
K
I
F
I
A
T
G
R
P
K
A
I
I
N
N
L
S
E
----
L
Q
D
R
N
L
I
----
D
----
G
Y
-
I
T
M
N
G
A
Y
C
--
F
V
G
--
E
E
V
-
I
Y
K
S
A
-
I
P
Q
E
E
V
-
K
A
M
A
-------
A
F
C
E
K
K
G
V
P
-
C
I
F
V
E
E
H
N
I
-----------
S
V
C
Q
P
-
N
------------
E
M
------
V
K
--------
K
I
F
Y
-
D
F
L
H
---
V
N
V
I
P
T
V
--
S
F
E
E
A
-
S
-
N
--
K
E
V
I
Q
-
M
T
P
F
I
-
T
E
E
-----
E
-----
E
K
E
---
V
----
L
P
---
S
I
----
P
-
T
------
C
E
I
--
G
R
W
Y
P
A
F
A
D
V
T
A
K
G
D
T
K
Q
K
G
I
D
E
I
I
R
H
F
G
I
K
L
E
E
T
M
S
F
G
D
G
G
N
D
I
S
M
L
R
H
A
A
I
G
V
A
M
G
Q
A
K
E
D
V
K
A
A
A
D
Y
--
V
T
A
P
I
D
E
D
G
I
S
K
A
M
K
H
F
G
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
87.96
24%
-72
- C3 -
3FZQ
7
?
A:
[6-274]
---
K
L
L
I
L
D
I
D
G
T
L
R
D
-
E
V
-
Y
-
G
I
P
E
S
A
K
H
A
I
R
L
C
Q
K
N
H
C
S
V
V
I
C
T
G
R
S
M
G
T
I
Q
D
D
V
L
----
S
--
L
G
-
V
----
D
----
G
Y
-
I
A
G
G
G
N
Y
I
--
Q
Y
H
--
G
E
L
-
L
Y
N
Q
S
-
F
N
Q
R
L
I
-
K
E
V
V
-------
C
L
L
K
K
R
E
V
A
-
F
S
I
E
S
Q
E
K
V
F
----
M
N
Q
K
A
K
E
I
F
E
T
M
N
Q
-----
L
----
K
G
T
N
S
--
C
I
N
K
Q
H
-
I
---
Q
E
K
I
--
T
Y
E
N
-
N
I
E
E
Y
K
S
Q
D
I
H
K
I
C
L
W
-
S
-
N
--
E
K
V
F
D
-
E
V
K
D
I
-
L
Q
D
-----
K
-----
M
E
L
---
A
----
Q
R
---
D
I
--------------------
S
S
Q
Y
-
Y
E
I
I
Q
K
D
F
H
K
G
K
A
I
K
R
L
Q
E
R
L
G
V
T
Q
K
E
T
I
C
F
G
D
G
Q
N
D
I
V
M
F
Q
A
S
D
V
T
I
A
M
K
N
S
H
Q
Q
L
K
D
I
A
T
S
--
I
C
E
D
I
F
D
N
G
I
Y
K
E
L
K
R
R
N
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
87.06
27%
-80
- C2 -
3NIW
2
?
A:
[6-265]
---
K
L
I
V
L
D
L
D
G
T
L
T
N
-
S
K
-
K
-
E
I
S
S
R
N
R
E
T
L
I
R
I
Q
E
Q
G
I
R
L
V
L
A
S
G
R
P
T
Y
G
I
V
P
L
A
N
----
E
--
L
R
-
M
----
N
EFGG
F
I
-
L
S
Y
N
G
G
E
I
IN
W
E
S
--
K
E
M
-
M
Y
E
N
V
-
L
P
N
E
V
V
-
P
V
L
---------
Y
E
C
A
R
T
N
H
-
L
S
I
L
T
Y
D
G
------------------------------
A
E
I
V
T
EN
S
L
D
P
Y
V
-
Q
---
K
E
A
--------
F
L
N
K
M
A
I
R
E
T
N
D
F
L
T
D
-
I
-
T
--
L
P
V
A
K
-
C
L
I
V
G
-
D
A
G
K
L
I
P
V
E
-----
S
E
L
---
C
----
I
R
---
L
Q
----
G
-
K
------
I
N
V
--
F
R
S
E
P
Y
F
L
E
L
V
P
Q
G
I
D
K
A
L
S
L
S
V
L
L
E
N
I
G
M
T
R
E
E
V
I
A
I
G
D
G
Y
N
D
L
S
M
I
K
F
A
G
M
G
V
A
M
G
N
A
Q
E
P
V
K
K
A
A
D
Y
--
I
T
L
T
N
D
E
D
G
V
A
E
A
I
E
R
I
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
114
HHSearch
87.03
23%
-82
- C3 -
3FZQ
7
?
A:
[4-273]
-
L
Y
K
L
L
I
L
D
I
D
G
T
L
R
D
-
E
V
-
Y
-
G
I
P
E
S
A
K
H
A
I
R
L
C
Q
K
N
H
C
S
V
V
I
C
T
G
R
S
M
G
T
I
Q
D
D
V
L
----
S
--
L
G
-
V
----
D
----
G
Y
-
I
A
G
G
G
N
Y
I
--
Q
Y
H
--
G
E
L
-
L
Y
N
Q
S
-
F
N
Q
R
L
I
-
K
E
V
V
-------
C
L
L
K
K
R
E
V
A
-
F
S
I
E
S
Q
E
K
V
------------
F
M
N
--
Q
K
-----
A
----
K
E
I
F
E
--
T
M
--
N
Q
-
L
---
K
G
T
-
N
S
C
I
N
K
Q
H
I
Q
E
K
I
T
-
Y
E
N
N
I
E
E
Y
-
K
-
S
--
Q
D
I
H
K
-
I
C
L
W
S
-
N
E
K
-----
V
-----
F
D
E
---
V
----
K
D
---
I
L
----
Q
-
D
K-----
M
E
L
AQ
R
D
I
S
S
Q
Y
Y
E
I
I
Q
K
D
F
H
K
G
K
A
I
K
R
L
Q
E
R
L
G
V
T
Q
K
E
T
I
C
F
G
D
G
Q
N
D
I
V
M
F
Q
A
S
D
V
T
I
A
M
K
N
S
H
Q
Q
L
K
D
I
A
T
S
--
I
C
E
D
I
F
D
N
G
I
Y
K
E
L
K
R
R
N
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
86.54
27%
-77
* C2 *
4DW8
4
?
A:
[6-265]
---
K
L
I
V
L
D
L
D
G
T
L
T
N
-
S
K
-
K
-
E
I
S
S
R
N
R
E
T
L
I
R
I
Q
E
Q
G
I
R
L
V
L
A
S
G
R
P
T
Y
G
I
V
P
L
A
N
----
E
--
L
R
-
M
----
N
EFGG
F
I
-
L
S
Y
N
G
G
E
I
IN
W
E
S
--
K
E
M
-
M
Y
E
N
V
-
L
P
N
E
V
V
-
P
V
L
---------
Y
E
C
A
R
T
N
H
-
L
S
I
L
T
Y
D
G
------------------------------
A
E
I
V
T
EN
S
L
D
P
Y
V
-
Q
---
K
E
A
--------
F
L
N
K
M
A
I
R
E
T
N
D
F
L
T
D
-
I
-
T
--
L
P
V
A
K
-
C
L
I
V
G
-
D
A
G
K
L
I
P
V
E
-----
S
E
L
---
C
----
I
R
---
L
Q
----
G
-
K
------
I
N
V
--
F
R
S
E
P
Y
F
L
E
L
V
P
Q
G
I
D
K
A
L
S
L
S
V
L
L
E
N
I
G
M
T
R
E
E
V
I
A
I
G
D
G
Y
N
D
L
S
M
I
K
F
A
G
M
G
V
A
M
G
N
A
Q
E
P
V
K
K
A
A
D
Y
--
I
T
L
T
N
D
E
D
G
V
A
E
A
I
E
R
I
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
125
HHSearch
85.93
27%
-80
- C3 -
3R4C
4
?
A:
[10-267]
H
M
I
K
V
L
L
L
D
V
D
G
T
L
L
S
-
F
E
T
H
-
K
V
S
Q
S
S
I
D
A
L
K
K
V
H
D
S
G
I
K
I
V
I
A
T
G
R
A
A
S
D
L
H
E
I
D
-----
A
--
V
P
-
Y
----
D
----
G
V
-
I
A
L
N
G
A
E
C
--
V
L
R
D-
G
S
V
-
I
R
K
V
A
-
I
P
A
Q
D
F
-
R
K
S
M
-------
E
L
A
R
E
F
D
F
A
-
V
A
L
E
L
N
E
G
V
F
------------
V
N
R
L
T
P
-----
T
----
V
E
----------
Q
-
I
---
A
G
I
V
---
E
H
P
---
V
P
P
V
V
D
I
-
E
E
M
F
E
R
------
K
E
C
C
Q
-
L
C
F
Y
F
-
D
E
E
-----
A
-----
E
Q
K
---
V
----
M
P
---
L
L
----
S
-
G
------
L
S
A
--
T
R
W
H
P
L
F
A
D
V
N
V
A
G
T
S
K
A
T
G
L
S
L
F
A
D
Y
Y
R
V
K
V
S
E
I
M
A
C
G
D
G
G
N
D
I
P
M
L
K
A
A
G
I
G
V
A
M
G
N
A
S
E
K
V
Q
S
V
A
D
F
--
V
T
D
T
V
D
N
S
G
L
Y
K
A
L
K
H
F
G
V
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
85.84
29%
-82
- C3 -
3R4C
4
?
A:
[12-268]
--
I
K
V
L
L
L
D
V
D
G
T
L
L
S
F
E
T
-
H
-
K
V
S
Q
S
S
I
D
A
L
K
K
V
H
D
S
G
I
K
I
V
I
A
T
G
R
A
A
S
D
L
H
E
-------------
I
----
D
-----
A
-
V
P
Y
D
G
V
I
A
--
L
N
G
--
A
E
C
-
V
-----
L
R
D
G
S
V
-
I
R
K
V
A
IP
A
Q
D
F
R
K
S
M
E
L
A
R
E
-
F
D
F
A
V
A
L
E
L
------------------
N
-----
E
----
G
V
F
V
N
--
R
L
T
P
T
------
V
E
Q
I
A
G
I
V
E
H
-
P
V
----
P
P
V
V
D
I
E
E
M
F
-
E
-
R
--
K
E
C
C
Q
-
L
C
F
Y
F
-
D
E
E
-----
A
-----
E
Q
K
---
V
----
M
P
---
L
L
----
S
-
G
------
L
S
A
--
T
R
W
H
P
L
F
A
D
V
N
V
A
G
T
S
K
A
T
G
L
S
L
F
A
D
Y
Y
R
V
K
V
S
E
I
M
A
C
G
D
G
G
N
D
I
P
M
L
K
A
A
G
I
G
V
A
M
G
N
A
S
E
K
V
Q
S
V
A
D
F
--
V
T
D
T
V
D
N
S
G
L
Y
K
A
L
K
H
F
G
V
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
84.99
25%
-61
- C3 -
1RKQ
2
YIDA_ECOLI
A:
[3-271]
L
A
I
K
L
I
A
I
D
M
D
G
T
L
L
L
-
P
D
-
H
-
T
I
S
P
A
V
K
N
A
I
A
A
A
R
A
R
G
V
N
V
V
L
T
T
G
R
P
Y
A
G
V
H
N
Y
L
K
----
E
--
L
H
-
M
EQPG
D
----
Y
C
-
I
T
Y
N
G
A
L
V
--
Q
K
A
--
A
D
----
G
S
T
-
V
A
Q
T
A
L
S
Y
D
D
Y
-------
R
F
L
E
K
L
S
R
E
-
V
-------------
G
---
S
H
F
H
A
L
D
R
T
T
-----
L
Y
T
AN
R
D
I
S
Y
--
Y
T
V
H
E
S
-
F
---
V
A
T
I
P
L
V
F
C
E
--
A
E
K
M
D
P
N
T
Q
F
L
K
V
M
M
-
I
-
D
--
E
P
--
A
-
I
L
D
Q
A
-
I
A
R
-----
I
-----
P
Q
E
---
V
----
K
E
---
K
Y
----
T
-
V
------
L
K
-----
S
A
P
Y
F
L
E
I
L
D
K
R
V
N
K
G
T
G
V
K
S
L
A
D
V
L
G
I
K
P
E
E
I
M
A
I
G
D
Q
E
N
D
I
A
M
I
E
Y
A
G
V
G
V
A
V
D
N
A
I
P
S
V
K
E
V
A
N
F
--
V
T
K
S
N
L
E
D
G
V
A
F
A
I
E
K
Y
V
L
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
117
HHSearch
84.57
25%
-66
- C3 -
1RKQ
2
YIDA_ECOLI
A:
[3-272]
L
A
I
K
L
I
A
I
D
M
D
G
T
L
L
L
-
P
D
-
H
-
T
I
S
P
A
V
K
N
A
I
A
A
A
R
A
R
G
V
N
V
V
L
T
T
G
R
P
Y
A
G
V
H
N
Y
L
K
----
E
--
L
H
-
M
EQPG
D
----
Y
C
-
I
T
Y
N
G
A
L
V
--
Q
K
A
AD
G
S
T
-
V
A
Q
T
A
-
L
S
Y
D
D
Y
-
R
F
L
E
-------
K
L
S
R
E
V
G
S
H
-
F
H
A
L
D
R
T
T
L
------------
Y
T
A
-
N
R
D
-----
I
-----
S
Y
-----------
Y
----
T
-
V
H
E
S
F
V
-----
A
T
I
P
L
V
F
C
E
A
E
K
M
D
P
-
N
--
T
Q
F
L
K
-
V
M
M
I
D
-
E
P
A
-----
I
-----
L
D
Q
---
A
I
A
R
I
P
Q
---
E
V
----
K
E
K
------
Y
T
V
--
L
K
S
A
P
Y
F
L
E
I
L
D
K
R
V
N
K
G
T
G
V
K
S
L
A
D
V
L
G
I
K
P
E
E
I
M
A
I
G
D
Q
E
N
D
I
A
M
I
E
Y
A
G
V
G
V
A
V
D
N
A
I
P
S
V
K
E
V
A
N
F
--
V
T
K
S
N
L
E
D
G
V
A
F
A
I
E
K
Y
V
L
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
84.51
24%
-58
- C3 -
1NRW
3
YWPJ_BACSU
A:
[4-286]
--
M
K
L
I
A
I
D
L
D
G
T
L
L
N
-
S
K
-
H
-
Q
V
S
L
E
N
E
N
A
L
R
Q
A
Q
R
D
G
I
E
V
V
V
S
T
G
R
A
H
F
D
V
M
S
I
F
E
----
P
--
L
G
-
I
----
K
T
---
W
V
-
I
S
A
N
G
A
V
I
--
H
D
P
--
E
G
R
-
L
Y
H
H
E
T
I
D
K
K
R
A
-
Y
D
I
L
-------
S
W
L
E
S
E
N
Y
Y
-
Y
E
V
F
T
G
S
A
I
Y
TPQN
G
---
R
E
L
L
D
V
E
L
D
R
-----
F
R
S
--
A
N
P
E
A
--
D
L
S
V
L
K
-
Q
---
A
A
E
V
Q
Y
S
Q
S
G
-
F
A
Y
------
I
N
S
F
Q
E
L
-
F
-
E
AD
E
P
I
D
F
-
Y
N
I
L
G
-
F
S
F
-----
F
-----
K
E
K
---
L
----
E
A
---
G
W
----
K
-
R
YEHAED
L
T
L
--
V
S
S
A
E
H
N
F
E
L
S
S
R
K
A
S
K
G
Q
A
L
K
R
L
A
K
Q
L
N
I
P
L
E
E
T
A
A
V
G
D
S
L
N
D
K
S
M
L
E
A
A
G
K
G
V
A
M
G
N
A
R
E
D
I
K
S
I
A
D
A
--
V
T
L
T
N
D
E
H
G
V
A
H
M
M
K
H
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
119
HHSearch
84.30
23%
-81
- C3 -
3DAO
1
?
A:
[19-283]
G
M
I
K
L
I
A
T
D
I
D
G
T
L
V
K
-
D
G
-
S
L
L
I
D
P
E
Y
M
S
V
I
D
R
L
I
D
K
G
I
I
F
V
V
C
S
G
R
Q
F
S
S
E
F
K
L
F
A
----
P
--
I
K
-
H
K---
L
----
L
Y
-
I
T
D
G
G
T
V
V
--
R
T
P
--
K
E
I
-
L
K
T
Y
P
-
M
D
E
D
I
W
-
K
G
M
C
-------
R
M
V
R
D
E
L
P
A
-
C
D
Y
F
A
A
T
P
------
D
---
F
C
F
A
E
D
G
G
S
P
------------
I
F
---------------
H
L
L
R
D
S
Y
------
G
F
E
M
R
E
V
D
D
I
T
R
L
-
D
-
R
--
N
D
I
I
K
-
F
T
V
F
H
-
P
D
K
-----
C
-----
E
E
L
C
TP
V
F---
I
P
---
A
W
N---
K
-
K
------
A
H
L
--
A
A
A
G
K
E
W
V
D
C
N
A
K
G
V
S
K
W
T
A
L
S
Y
L
I
D
R
F
D
L
L
P
D
E
V
C
C
F
G
D
N
L
N
D
I
E
M
L
Q
N
A
G
I
S
Y
A
V
S
N
A
R
Q
E
V
I
A
A
A
K
H
--
T
C
A
P
Y
W
E
N
G
V
L
S
V
L
K
S
F
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
116
HHSearch
83.17
25%
-67
- C3 -
1NRW
3
YWPJ_BACSU
A:
[4-288]
--
M
K
L
I
A
I
D
L
D
G
T
L
L
N
-
S
K
-
H
-
Q
V
S
L
E
N
E
N
A
L
R
Q
A
Q
R
D
G
I
E
V
V
V
S
T
G
R
A
H
F
D
V
M
S
I
F
E
----
P
--
L
G
-
I
K---
T
----
W
V
-
I
S
A
N
G
A
V
I
--
H
D
P
E-
G
R
L
-
Y
H
H
E
T
-
I
D
K
K
R
A
-
Y
D
I
L
-------
S
W
L
E
S
E
N
Y
Y
-
Y
E
V
F
T
G
S
A
I
Y
-----------
T
P
Q
N
G
R
E
L
L
D
V
E
L
----
D
R
F
R
S
---
A
N
P
E
A
D
L
S
V
L
K
Q
A
A
E
V
Q
Y
S
Q
-
S
G
F
A
Y
I
N
S
-
F
Q
E
L
F
E
A
-
D
E
P
--
I
D
F
Y
N
-
I
L
G
F
S
F
F
K
E
-----
K
-----
L
E
A
---
G
----
W
K
R
YE
H
A
----
E
-
D
------
L
T
L
--
V
S
S
A
E
H
N
F
E
L
S
S
R
K
A
S
K
G
Q
A
L
K
R
L
A
K
Q
L
N
I
P
L
E
E
T
A
A
V
G
D
S
L
N
D
K
S
M
L
E
A
A
G
K
G
V
A
M
G
N
A
R
E
D
I
K
S
I
A
D
A
--
V
T
L
T
N
D
E
H
G
V
A
H
M
M
K
H
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
81.83
24%
-71
- C3 -
3DNP
1
YHAX_BACSU
A:
[11-273]
-------
L
N
I
D
G
A
L
L
R
-
S
N
-
G
-
K
I
H
Q
A
T
K
D
A
I
E
Y
V
K
K
K
G
I
Y
V
T
L
V
T
N
R
H
F
R
S
A
Q
K
I
A
K
----
S
--
L
K
-
L
----
D
----
A
K
L
I
T
H
S
G
A
Y
I
--
A
E
K
--
I
D
A
P
F
F
E
K
R
-
I
S
D
D
H
T
-
F
N
I
V
-------
Q
V
L
E
S
Y
Q
C
N
-
I
R
L
L
H
E
K
Y
S
I
----
G
---
N
K
------------------
K
K
V
N
S
--
N
L
L
G
K
A
-
L
---
I
H
P
S
D
P
I
F
-------
Y
P
V
Q
F
V
E
S
L
S
D
L
-
L
-
M
D-
E
P
V
S
A
P
V
I
E
V
Y
-
T
E
H
-----
D
I
Q
H
D
I
T
E
T
---
I
----
T
K
---
A
F
----
P
-
A
------
V
D
V
--
I
R
V
N
D
E
K
L
N
I
V
P
K
G
V
S
K
E
A
G
L
A
L
V
A
S
E
L
G
L
S
M
D
D
V
V
A
I
G
H
Q
Y
D
D
L
P
M
I
E
L
A
G
L
G
V
A
M
G
N
A
V
P
E
I
K
R
K
A
D
W
--
V
T
R
S
N
D
E
Q
G
V
A
Y
M
M
K
E
Y
F
R
M
Q
Q
R
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
118
HHSearch
81.52
25%
-70
- C3 -
3PGV
9
?
A:
[21-284]
--
Y
Q
V
V
A
S
D
L
D
G
T
L
L
S
-
P
D
-
H
-
F
L
T
P
Y
A
K
E
T
L
K
L
L
T
A
R
G
I
N
F
V
F
A
T
G
R
H
Y
I
D
V
G
Q
I
R
D
----
N
--
L
G
-
I
R
---
S
----
Y
M
-
I
T
S
N
G
A
R
V
--
H
D
S
D-
G
Q
Q
-
I
F
A
H
N
-
L
D
R
D
I
A
-
A
D
L
F
-------
E
I
V
R
N
D
P
K
I
V
T
N
V
Y
R
E
D
E
W
Y
-----------
M
N
R
H
-
R
-----------------------------------
F
F
K
E
-
A
--
V
F
-
N
Y
K
L
Y
E
P
G
E
L
-
D
-
P
--
Q
G
I
S
K
-
V
F
F
T
C
-
E
D
H
E----
H
-----
L
L
P
---
L
----
E
Q
---
A
M
N
A
R
W
G
D
R
------
V
N
V
--
S
F
S
T
L
T
C
L
E
V
M
A
G
G
V
S
K
G
H
A
L
E
A
V
A
K
M
L
G
Y
T
L
S
D
C
I
A
F
G
D
G
M
N
D
A
E
M
L
S
M
A
G
K
G
C
I
M
A
N
A
H
Q
R
L
K
D
L
H
P
E
L
E
V
I
G
S
N
A
D
D
A
V
P
R
Y
L
R
K
L
Y
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------