@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1767: (2015-12-10 )
MNTIVMQADKKLQEKIRTDLAQHHISNNNPYVVFSAKISGTTVLLYTSGKLVFQGSNASHIAQKYGYIEQKESCSSETQDIPIIGTDEVGNGSYFGGLAVVASFVTPKDHAYLKKLGVGDSKTLTDQKIKQIAPLLEKAIPHKALLLSPQKYNQVVGPNNKHNAVSVKVALHNQAIFLLLQDGFEPEKIVIDAFTSSKNYQNYLKNEKNQFKQTITLEEKAENKYLAVAVSSIIARNLFLENLNKLSDDVGYKLPSGAGHQSDKVASQLLKAYGISSLEHCAKLHFANTKKAQALLK
Atome Classification :
(20 SA)
.........10........20..-......30-........40........50........60......----------..----------70----------........80------------.........90........100.......110.......120......----.130......-.140........150.--...-.-..160--.........170.......180-.--.--.---...----..190..-..-..-.200....-------...------210.------......220.......230...---....240.......250.......260.......270--..----.--..-.--.-..280.......290.....--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
N
T
I
V
MQA
D
K
K
L
Q
E
K
I
R
T
D
L
A
Q
H
-HISNNN
P
Y
-
V
V
F
S
AKISG
T
T
V
L
L
YTS
G
K
L
V
F
QGS
N
A
S
H
I
A
Q
K
YGY----------
I
E
----------
Q
K
----------
E
SCSSETQD-------------
I
P
I
I
GTDEVGNGSYF
G
G
L
A
V
V
A
S
FVTP
K
D
H
A
Y
L
K
K
LGVGDSKT
L
T
D
Q
K
----
I
K
Q
I
A
P
L
L
E
K-AI-PH
K
A
L
LL
S
P
Q
K
Y
N
--QVV-G-PNN----KH
N
A
V
S
V
K
V
A
LHN
Q
A
I
F
L
L
L-Q-D--G--F---EP
E
----
K
I
V
I
D
A
F-TS-S
K
-
N
Y
Q
N
Y
L
K
N
-------
E
K
N
------
Q
F
K
Q
------
T
I
T
L
E
EKAEN
K
Y
L
A
V
A
V
S
S
I
I
A
---
R
N
L
F
L
E
N
L
N
K
L
S
D
DVGYKLPSGAGH
Q
S
D
K
V
A
S
Q
L
L
----
K
A
----Y--G
I
-
S
--
S
-
L
E
H
C
A
K
L
HFAN
T
K
K
A
Q
A
LLK--
3
PsiBlast_PDB
99.44
38%
-84
- C4 -
2D0C
1
?
A:
[2-307]
-
S
N
Y
V
I
Q
A
D
Q
Q
L
L
D
A
L
R
A
H
Y
-
E
G
-
A
L
S
D
R
L
P
A
G
A
L
F
A
V
K
R
P
D
V
V
I
T
A
Y
R
S
G
K
V
L
F
Q
G
K
A
A
E
Q
E
A
A
K
W
-------------
I
----------
S
G
----------
A
S
A
S
N
E
T
A
D
HQPSA
L
A
A
H
Q
LGS
L
S
A
I
G
S
D
E
V
G
T
G
D
Y
F
G
P
I
V
V
A
A
A
Y
V
D
R
P
H
I
A
K
I
A
A
L
G
V
K
D
S
K
Q
L
N
D
E
A
----
I
K
R
I
A
P
A
I
M
E
-
T
V
-
P
H
A
V
T
V
L
D
N
P
Q
Y
N
R
W
Q
R
S
-
G
M
P
Q
T
----
K
M
K
A
L
-----
L
H
N
R
T
L
V
K
L
V
---
D
--
A
--
I
APA
E
P
E
----
A
I
I
I
D
E
F
-
L
K
-
R
D
-
S
Y
F
R
Y
L
S
D
-------
E
D
R
------
I
I
R
E
------
R
V
H
C
L
P
K
A
E
S
V
H
V
S
V
A
A
A
S
I
I
A
---
R
Y
V
F
L
E
E
M
E
Q
L
S
R
A
V
G
L
L
L
P
K
G
A
G
A
I
V
D
E
A
A
A
R
I
I
----
R
A
----
R
--
G
E
-
E
--
M
-
L
E
T
C
A
K
L
H
F
A
N
T
K
K
A
L
A
I
A
K
--
1
PsiBlast_PDB
99.42
38%
-79
- C4 -
2D0A
-
?
A:
[2-307]
-
S
N
Y
V
I
Q
A
D
Q
Q
L
L
D
A
L
R
A
H
Y
-
E
G
-
A
L
S
D
R
L
P
A
G
A
L
F
A
V
K
R
P
D
V
V
I
T
A
Y
R
S
G
K
V
L
F
Q
G
K
A
A
E
Q
E
A
A
K
W
-------------
I
----------
S
G
----------
A
S
A
S
N
E
T
A
D
HQPSA
L
A
A
H
Q
LGS
L
S
A
I
G
S
D
E
V
G
T
G
D
Y
F
G
P
I
V
V
A
A
A
Y
V
D
R
P
H
I
A
K
I
A
A
L
G
V
K
D
S
K
Q
L
N
D
E
A
----
I
K
R
I
A
P
A
I
M
E
-
T
V
-
P
H
A
V
T
V
L
D
N
P
Q
Y
N
R
W
Q
R
S
-
G
M
P
Q
T
----
K
M
K
A
L
-----
L
H
N
R
T
L
V
K
L
V
---
D
--
A
--
I
APA
E
P
E
----
A
I
I
I
D
E
F
-
L
K
-
R
D
-
S
Y
F
R
Y
L
S
D
-------
E
D
R
------
I
I
R
E
------
R
V
H
C
L
P
K
A
E
S
V
H
V
S
V
A
A
A
S
I
I
A
---
R
Y
V
F
L
E
E
M
E
Q
L
S
R
A
V
G
L
L
L
P
K
G
A
G
A
I
V
D
E
A
A
A
R
I
I
----
R
A
----
R
--
G
E
-
E
--
M
-
L
E
T
C
A
K
L
H
F
A
N
T
K
K
A
L
A
I
A
K
--
2
PsiBlast_PDB
99.05
38%
-84
- C4 -
2D0B
1
?
A:
[2-307]
-
S
N
Y
V
I
Q
A
D
Q
Q
L
L
D
A
L
R
A
H
Y
-
E
G
-
A
L
S
D
R
L
P
A
G
A
L
F
A
V
K
R
P
D
V
V
I
T
A
Y
R
S
G
K
V
L
F
Q
G
K
A
A
E
Q
E
A
A
K
W
-------------
I
----------
S
G
----------
A
S
A
S
N
E
T
A
D
HQPSA
L
A
A
H
Q
LGS
L
S
A
I
G
S
D
E
V
G
T
G
D
Y
F
G
P
I
V
V
A
A
A
Y
V
D
R
P
H
I
A
K
I
A
A
L
G
V
K
D
S
K
Q
L
N
D
E
A
----
I
K
R
I
A
P
A
I
M
E
-
T
V
-
P
H
A
V
T
V
L
D
N
P
Q
Y
N
R
W
Q
R
S
-
G
M
P
Q
T
----
K
M
K
A
L
-----
L
H
N
R
T
L
V
K
L
V
---
D
--
A
--
I
APA
E
P
E
----
A
I
I
I
D
E
F
-
L
K
-
R
D
-
S
Y
F
R
Y
L
S
D
-------
E
D
R
------
I
I
R
E
------
R
V
H
C
L
P
K
A
E
S
V
H
V
S
V
A
A
A
S
I
I
A
---
R
Y
V
F
L
E
E
M
E
Q
L
S
R
A
V
G
L
L
L
P
K
G
A
G
A
I
V
D
E
A
A
A
R
I
I
----
R
A
----
R
--
G
E
-
E
--
M
-
L
E
T
C
A
K
L
H
F
A
N
T
K
K
A
L
A
I
A
K
--
4
PsiBlast_PDB
98.55
37%
-84
- C4 -
3ASM
-
?
A:
[2-307]
-
S
N
Y
V
I
Q
A
D
Q
Q
L
L
D
A
L
R
A
H
Y
-
E
G
-
A
L
S
D
R
L
P
A
G
A
L
F
A
V
K
R
P
D
V
V
I
T
A
Y
R
S
G
K
V
L
F
A
G
K
A
A
E
Q
E
A
A
K
W
-------------
I
----------
S
G
----------
A
S
A
S
N
E
T
A
D
HQPSA
L
A
A
H
Q
L
GS
L
S
A
I
G
S
D
E
V
G
T
G
D
Y
F
G
P
I
V
V
A
A
A
Y
V
D
R
P
H
I
A
K
I
A
A
L
G
V
K
D
S
K
Q
L
N
D
E
A
----
I
K
R
I
A
P
A
I
M
E
-
T
V
-
P
H
A
V
T
V
L
D
N
P
Q
Y
N
R
W
Q
R
S
-
G
M
P
Q
T
----
K
M
K
A
L
-----
L
H
N
R
T
L
V
K
L
V
---
D
--
A
--
I
APA
E
P
E
----
A
I
I
I
D
E
F
-
L
K
-
R
D
-
S
Y
F
R
Y
L
S
D
-------
E
D
R
------
I
I
R
E
------
R
V
H
C
L
P
K
A
E
S
V
H
V
S
V
A
A
A
S
I
I
A
---
R
Y
V
F
L
E
E
M
E
Q
L
S
R
A
V
G
L
L
L
P
K
G
A
G
A
I
V
D
E
A
A
A
R
I
I
----
R
A
----
R
--
G
E
-
E
--
M
-
L
E
T
C
A
K
L
H
F
A
N
T
K
K
A
L
A
I
A
K
--
42
Fugue
97.87
36%
-85
- C4 -
3ASM
-
?
A:
[2-309]
-
S
N
Y
V
I
Q
A
D
Q
Q
L
L
D
A
L
R
A
H
Y
E
G
A
-
L
S
D
R
L
P
A
G
-
A
L
F
A
V
K
R
P
D
V
V
I
T
A
Y
R
S
G
K
V
L
F
A
G
K
A
A
E
Q
E
A
A
K
W
I
S
----------
G
A
----------
S
A
S
NETADHQPS
A
L
A
A
H
Q
L
G
S
-------------
L
S
A
I
G
S
D
E
V
G
T
G
D
Y
F
G
P
I
V
V
A
A
A
Y
V
D
R
P
H
I
A
K
I
A
A
L
G
V
K
D
S
K
Q
L
N
D
E
A
----
I
K
R
I
A
P
A
I
M
E
-
T
V
-
P
H
A
V
T
V
L
D
N
P
Q
Y
N
--
R
W
Q
-
R
-
S
G
------
M
P
Q
T
K
M
K
A
L
L
H
N
R
T
L
V
K
L
V
-
D
-
A
I
A
P
--
A
---
E
P
E
----
A
I
I
I
D
E
F
-
L
K
-
R
D
-
S
Y
F
R
Y
L
S
D
-------
E
D
R
------
I
I
R
E
------
R
V
H
C
L
P
K
A
E
S
V
H
V
S
V
A
A
A
S
I
I
A
---
R
Y
V
F
L
E
E
M
E
Q
L
S
R
A
V
G
L
L
L
P
K
G
A
G
A
I
V
D
E
A
A
A
R
I
I
----
R
A
----
R
--
G
E
-
E
--
M
-
L
E
T
C
A
K
L
H
F
A
N
T
K
K
A
L
A
I
A
K
RR
21
HHSearch
97.82
37%
-85
- C4 -
2D0B
1
?
A:
[2-307]
-
S
N
Y
V
I
Q
A
D
Q
Q
L
L
D
A
L
R
A
H
Y
E
G
A
-
L
S
D
R
L
P
A
G
-
A
L
F
A
V
K
R
P
D
V
V
I
T
A
Y
R
S
G
K
V
L
F
Q
G
K
A
A
E
Q
E
A
A
K
W
I
S
----------
G
A
S
A
S
NETADHQ
P
S
----------
A
L
A
A
H
Q
L
G
S
-------------
L
S
A
I
G
S
D
E
V
G
T
G
D
Y
F
G
P
I
V
V
A
A
A
Y
V
D
R
P
H
I
A
K
I
A
A
L
G
V
K
D
S
K
Q
L
N
D
E
A
----
I
K
R
I
A
P
A
I
M
E
-
T
V
-
P
H
A
V
T
V
L
D
N
P
Q
Y
N
--
R
W
Q
-
R
-
S
G
------
M
P
Q
T
K
M
K
A
L
L
H
N
R
T
L
V
K
L
V
D
A
I
A
--
P
--
A
---
E
P
E
----
A
I
I
I
D
E
F
-
L
K
-
R
D
-
S
Y
F
R
Y
L
S
D
-------
E
D
R
------
I
I
R
E
------
R
V
H
C
L
P
K
A
E
S
V
H
V
S
V
A
A
A
S
I
I
A
---
R
Y
V
F
L
E
E
M
E
Q
L
S
R
A
V
G
L
L
L
P
K
G
A
G
A
I
V
D
E
A
A
A
R
I
I
----
R
A
----
R
--
G
E
-
E
--
M
-
L
E
T
C
A
K
L
H
F
A
N
T
K
K
A
L
A
I
A
K
--
43
Fugue
94.45
34%
-80
- C4 -
2D0B
1
?
A:
[2-309]
-
S
N
Y
V
I
Q
A
D
Q
Q
L
L
D
A
L
R
A
H
Y
E
G
A
-
L
S
D
R
L
P
A
G
-
A
L
F
A
V
K
R
P
D
V
V
I
T
A
Y
R
S
G
K
V
L
F
Q
G
K
A
A
E
Q
E
A
A
K
W
I
S
G
A
S
A
S
NETAD
H
Q
----------
P
S
----------
A
L
A
A
H
Q
L
G
S
-------------
L
S
A
I
G
S
D
E
V
G
T
G
D
Y
F
G
P
I
V
V
A
A
A
Y
V
D
R
P
H
I
A
K
I
A
A
L
G
V
K
D
S
K
Q
L
N
D
E
A
----
I
K
R
I
A
P
A
I
M
E
-
T
V
-
P
H
A
V
T
V
L
D
N
P
Q
Y
N
--
R
W
Q
-
R
-
S
G
M
----
P
Q
T
K
M
K
A
L
L
H
N
R
T
L
V
K
L
V
D
A
-
I
-
A
--
P
--
A
---
E
P
E
----
A
I
I
I
D
E
F
-
L
K
-
R
D
-
S
Y
F
R
Y
L
S
D
-------
E
D
R
------
I
I
R
E
------
R
V
H
C
L
P
K
A
E
S
V
H
V
S
V
A
A
A
S
I
I
A
---
R
Y
V
F
L
E
E
M
E
Q
L
S
R
A
V
G
L
L
L
P
K
G
A
G
A
I
V
D
E
A
A
A
R
I
I
----
R
A
----
R
--
G
E
-
E
--
M
-
L
E
T
C
A
K
L
H
F
A
N
T
K
K
A
L
A
I
A
K
R
R
22
HHSearch
79.87
25%
-82
* C4 *
3VN5
-
RNH3_AQUAE
A:
[2-256]
---
P
S
L
K
I
S
P
S
E
A
E
K
I
Q
N
Y
L
V
S
S
G
F
R
K
I
N
A
P
Y
-
T
L
W
A
L
E
G
N
G
V
K
V
Y
Y
Y
K
T
G
S
L
L
I
Q
G
K
N
S
E
K
V
L
K
E
V
L
---------------------------------------
N
L
L
E
K
-------------
K
K
L
P
G
C
D
E
S
G
K
G
D
I
F
G
S
L
V
L
C
C
V
C
I
P
E
E
N
Y
L
K
V
S
S
L
N
P
R
D
T
K
R
L
S
D
K
R
----
V
E
R
L
Y
L
A
L
K
P
-
L
V
-
K
A
Y
C
Y
E
I
K
P
E
E
Y
N
--
K
L
Y
-
R
-
K
F
------
R
N
L
N
K
M
M
T
H
F
Y
K
L
L
I
E
R
V
K
-
E
-
E
-----
C
---
G
V
S
----
E
V
V
V
D
K
Y
-
Q
P
-
S
N
-
P
------------------------
F
G
E
------
D
V
I
F
E
T
E
A
E
-
R
N
L
A
V
A
V
A
S
I
F
A
---
R
Y
K
F
L
Q
S
L
K
E
V
E
R
E
L
G
I
K
I
P
K
G
T
S
K
E
V
K
E
L
A
K
S
L
K
----
N
----------------
P
E
R
F
I
K
L
N
F
N
------------
6
PsiBlast_PDB
78.64
27%
-77
- C4 -
4PY5
10
?
A:
[32-266]
-----------------------------------
Y
R
L
R
L
N
D
A
I
L
T
V
Y
K
S
G
S
V
V
Y
G
G
K
G
R
E
K
L
K
E
L
V
A
-----------------------------------
E
T
V
L
S
D
T
E
--------------
L
P
R
I
G
C
N
E
A
G
K
G
E
F
V
G
P
L
V
V
A
C
I
V
A
D
E
K
C
L
K
R
L
I
E
L
G
V
K
D
S
K
K
L
S
N
E
K
----
V
E
E
L
A
S
E
I
T
E
-
T
C
-
H
G
K
V
K
L
L
I
P
E
K
Y
N
--
R
A
Y
-----
S
----
K
F
K
N
I
N
R
L
L
E
A
V
Y
R
E
I
V
S
D
L
-
C
-
E
--
K
--
F
---
S
P
K
----
V
V
V
V
D
K
F
----
S
N
-
R
A
E
E
V
L
K
D
-------
V
V
K
------
G
A
R
--------
L
E
V
R
P
K
A
E
D
D
-
L
A
V
A
A
A
S
I
V
A
---
K
A
V
R
L
K
T
M
K
E
L
E
K
R
F
K
V
K
L
P
E
G
-----
N
T
G
L
A
E
L
L
----
K
K
----
T
--
P
K
-
E
--
L
-
H
E
K
L
F
K
L
H
F
S
V
-----------
5
PsiBlast_PDB
73.34
25%
-81
- C4 -
3VN5
-
RNH3_AQUAE
A:
[27-244]
----------------------------
N
A
P
Y
-
T
L
W
A
L
E
G
N
G
V
K
V
Y
Y
Y
K
T
G
S
L
L
I
Q
G
K
N
S
E
K
V
L
K
E
V
L
N
----------
L
L
----------
E
K
-----------------
K
K
-------------
L
P
--
G
C
D
E
S
G
K
G
D
I
F
G
S
L
V
L
C
C
V
C
I
P
E
E
N
Y
L
K
V
S
S
L
N
P
R
D
T
K
R
L
S
D
K
R
----
V
E
R
L
Y
L
A
L
K
P
-
L
V
-
K
A
Y
C
Y
E
I
K
P
E
E
Y
N
--
K
L
Y
-
R
-
K
F
R
----
N
L
N
----
K
M
M
T
H
---
F
Y
K
L
L
-
I
-
E
--
R
--
V
---
K
E
E
CGVS
E
V
V
V
D
K
Y
-
Q
P
-
S
-------------------
N
------
P
F
G
E
------
D
V
I
F
E
T
E
A
E
-
R
N
L
A
V
A
V
A
S
I
F
A
---
R
Y
K
F
L
Q
S
L
K
E
V
E
R
E
L
G
I
K
I
P
K
G
T
S
K
E
V
K
E
L
A
K
S
L
K
----
N
P
----
E
--
R
F
-
I
--
K
-
L
N
F
N
------------------
23
HHSearch
71.53
28%
-68
- C4 -
1EKE
1
RNH2_METJA
A:
[1-222]
-----------------------------------------------------------------------------------------------------------------------------
M
I
I
I
G
I
D
E
A
G
R
G
P
V
L
G
P
M
V
V
C
A
F
A
I
E
K
E
R
E
E
E
L
K
K
L
G
V
K
---
E
L
T
K
N
K
----
R
A
Y
L
K
K
L
L
E
N
-
L
G
-
Y
V
E
K
R
I
L
E
A
E
E
I
N
--
Q
L
M
-
N
--
S
------
I
N
L
N
D
I
E
I
N
A
F
S
K
V
A
K
N
L
I
E
K
-
L
--
N
IR
D
---
D
E
I
----
E
I
Y
I
D
A
C
-
S
T
-
N
T
K
K
F
E
D
S
F
K
D
-------
K
I
E
DIIKER
N
L
N
I
------
K
I
I
A
E
H
K
A
D
A
K
Y
P
V
V
S
A
A
S
I
I
A
---
K
A
E
R
D
E
I
I
D
Y
Y
K
K
I
Y
G
---
D
I
G
S
G
Y
P
S
D
P
K
T
I
K
F
L
----
E
D
----
Y
--
F
K
-
K
H
K
K
-
L
P
D
I
A
R
T
H
W
K
T
C
K
R
I
L
D
K
S
K
--
27
HHSearch
71.46
25%
-64
- C4 -
1UAX
-
RNH2_PYRHO
A:
[1-207]
-----------------------------------------------------------------------------------------------------------------------------
M
K
V
A
G
V
D
E
A
G
R
G
P
V
I
G
P
L
V
I
G
V
A
V
I
D
E
K
N
I
E
R
L
R
D
I
G
V
K
D
S
K
Q
L
T
P
G
Q
----
R
E
K
L
F
S
K
L
I
D
-
I
L
D
D
Y
Y
V
L
L
V
T
P
K
E
I
D
--
E
R
H
-----------
H
S
M
N
E
L
E
A
E
K
F
V
V
A
L
N
S
L
R
-
I
-----------
K
P
Q
----
K
I
Y
V
D
S
A
-
D
V
D
P
K
-
R
F
A
S
L
I
K
A
-------
G
L
K
-------
Y
E
A
------
T
V
I
A
E
H
K
A
D
A
K
Y
E
I
V
S
A
A
S
I
I
A
---
K
V
T
R
D
R
E
I
E
K
L
K
Q
K
Y
G
---
E
F
G
S
G
Y
P
S
D
P
R
T
K
E
W
L
----
E
E
Y
Y
K
Q
Y
--
G
-----
D
-
F
P
P
I
V
R
R
T
W
E
T
A
R
K
I
E
E
R
F
R
--
10
PsiBlast_PDB
70.56
26%
-58
- C4 -
3P83
-
RNH2_ARCFU
D:
[4-191]
---------------------------------------------------------------------------------------------------------------------------------
G
I
D
E
A
G
K
G
C
V
I
G
P
L
V
V
A
G
--
V
A
C
S
D
E
D
R
L
R
K
L
G
V
K
D
S
K
K
L
S
Q
G
R
----
R
E
E
L
A
E
E
I
R
K
-
I
C
-
R
T
E
V
L
K
V
S
P
E
N
L
D
--
E
------------
R
M
A
A
K
T
I
N
E
I
L
K
E
C
Y
A
E
I
I
L
-
R
-------
L
---
K
P
E
----
I
A
Y
V
D
----
S
-
P
D
-
V
I
P
E
R
L
S
R
-------
E
L
E
------
E
I
T
G
L-----
R
V
V
A
E
H
K
A
D
E
K
Y
P
L
V
A
A
A
S
I
I
A
---
K
V
E
R
E
R
E
I
E
R
L
K
E
K
F
G
D
---
F
G
S
G
Y
A
S
D
P
R
T
R
E
V
L
----
K
E
----
W
--
I
A
-
S
--
G
R
I
P
S
C
V
R
M
R
W
K
T
V
S
N
L
R
Q
K
T
L
--
24
HHSearch
70.36
23%
-65
- C4 -
1IO2
-
RNH2_THEKO
A:
[1-208]
-----------------------------------------------------------------------------------------------------------------------------
M
K
I
A
G
I
D
E
A
G
R
G
P
V
I
G
P
M
V
I
A
A
V
V
V
D
E
N
S
L
P
K
L
E
E
L
K
V
R
D
S
K
K
L
T
P
K
R
----
R
E
K
L
F
N
E
I
L
G
-
V
L
D
D
Y
V
I
L
E
L
P
P
D
V
I
G
--
S
R
-----
E
------
G
T
L
N
E
F
E
V
E
N
F
A
K
A
L
N
S
L
K
-
V
-----------
K
P
D
----
V
I
Y
A
D
A
A
-
D
V
D
E
E
-
R
F
A
R
E
L
G
E
-------
R
L
N
-------
F
E
A
------
E
V
V
A
K
H
K
A
D
D
I
F
P
V
V
S
A
A
S
I
L
A
---
K
V
T
R
D
R
A
V
E
K
L
K
E
E
Y
G
---
E
I
G
S
G
Y
P
S
D
P
R
T
R
A
F
L
E
N
Y
Y
R
E
----
H
--
G
-----
E
-
F
P
P
I
V
R
K
G
W
K
T
L
K
K
I
A
E
K
V
E
--
11
PsiBlast_PDB
70.28
30%
-79
- C4 -
1EKE
1
RNH2_METJA
A:
[3-217]
-------------------------------------------------------------------------------------------------------------------------------
I
I
G
I
D
E
A
G
R
G
P
V
L
G
P
M
V
V
C
A
F
A
I
E
K
E
R
E
E
E
L
K
K
L
G
V
K
---
E
L
T
K
N
K
----
R
A
Y
L
K
K
L
L
E
N
-
L
G
-
Y
V
E
K
R
I
L
E
A
E
E
I
N
--
Q
L
M
-
N
-
S
I
N
L
N
D
I
E
I
N
A
F
S
-
K
V
A
K
N
L
I
E
K
L
N
I
R
-
D
-
D
--
E
--
I
---
E
-------
I
Y
I
D
A
C
S
T
N
-
T
K
-
K
F
E
D
S
F
K
D
K
I
EDIIK
E
R
N
-------
L
N
I
------
K
I
I
A
E
H
K
A
D
A
K
Y
P
V
V
S
A
A
S
I
I
A
K
A
E
R
D
E
I
I
D
Y
Y
K
K
I
Y
G
D
I
------
G
S
G
Y
P
S
D
P
K
T
I
K
F
L
----
E
D
----
Y
F
K
K
H
-
K
--
K
-
L
P
D
I
A
R
T
H
W
K
T
C
K
R
I
L
D
K
S
K
--
25
HHSearch
69.96
24%
-70
- C4 -
1I39
-
RNH2_ARCFU
A:
[1-200]
------------------------------------------------------------------------------------------------------------------------------
M
K
A
G
I
D
E
A
G
K
G
C
V
I
G
P
L
V
V
A
G
V
A
C
S
D
E
--
D
R
L
R
K
L
G
V
K
D
S
K
K
L
S
Q
G
R
----
R
E
E
L
A
E
E
I
R
K
-
I
C
-
R
T
E
V
L
K
V
S
P
E
N
L
D
--
E
R
M
-
A
--
A
------
K
T
I
N
E
I
L
K
E
C
Y
A
E
I
I
L
R
L
K
--------------
P
E
----
I
A
Y
V
D
S
P
-
D
V
I
P
E
-
R
L
S
R
E
L
E
E
-------
I
T
---------
G
L
------
R
V
V
A
E
H
K
A
D
E
K
Y
P
L
V
A
A
A
S
I
I
A
---
K
V
E
R
E
R
E
I
E
R
L
K
E
K
F
G
---
D
F
G
S
G
Y
A
S
D
P
R
T
R
E
V
L
----
K
E
----
W
--
I
A
S
G
--
R
-
I
P
S
C
V
R
M
R
W
K
T
V
S
N
L
R
Q
K
----
44
Fugue
69.92
28%
-59
- C4 -
1EKE
1
RNH2_METJA
A:
[2-225]
------------------------------------------------------------------------------------------------------------------------------
I
I
I
G
I
D
E
A
G
R
G
P
V
L
G
P
M
V
V
C
A
F
A
I
E
K
E
R
E
E
E
L
K
K
L
G
V
K
---
E
L
T
K
N
K
----
R
A
Y
L
K
K
L
L
E
N
L
G
--
Y
V
E
K
R
I
L
E
A
E
E
I
N
--
Q
L
-
M
N
-
S
I
N
----
L
N
D
I
E
I
N
A
F
S
K
V
A
K
N
L
I
E
K
L
-
N
-
I
--
R
--
D
---
D
E
I
----
E
I
Y
I
D
A
C
S
T
N
-
T
K
-
K
F
E
D
S
F
K
D
-------
K
I
E
------
D
I
I
K
ERNLN
I
K
I
I
A
E
H
K
A
D
A
K
Y
P
V
V
S
A
A
S
I
I
A
---
K
A
E
R
D
E
I
I
D
Y
Y
K
K
I
Y
G
---
D
I
G
S
G
Y
P
S
D
P
K
T
I
K
F
L
----
E
D
----
Y
--
F
K
-
K
H
K
K
-
L
P
D
I
A
R
T
H
W
K
T
C
K
R
I
L
D
K
S
K
QT
8
PsiBlast_PDB
69.38
26%
-63
- C4 -
1I39
-
RNH2_ARCFU
A:
[4-191]
---------------------------------------------------------------------------------------------------------------------------------
G
I
D
E
A
G
K
G
C
V
I
G
P
L
V
V
A
G
--
V
A
C
S
D
E
D
R
L
R
K
L
G
V
K
D
S
K
K
L
S
Q
G
R
----
R
E
E
L
A
E
E
I
R
K
-
I
C
-
R
T
E
V
L
K
V
S
P
E
N
L
D
--
E
------------
R
M
A
A
K
T
I
N
E
I
L
K
E
C
Y
A
E
I
I
L
-
R
-------
L
---
K
P
E
----
I
A
Y
V
D
----
S
-
P
D
-
V
I
P
E
R
L
S
R
-------
E
L
E
------
E
I
T
G
L
-----
R
V
V
A
E
H
K
A
D
E
K
Y
P
L
V
A
A
A
S
I
I
A
---
K
V
E
R
E
R
E
I
E
R
L
K
E
K
F
G
---
D
F
G
S
G
Y
A
S
D
P
R
T
R
E
V
L
----
K
E
----
W
--
I
A
-
S
--
G
R
I
P
S
C
V
R
M
R
W
K
T
V
S
N
L
R
Q
K
----
9
PsiBlast_PDB
69.17
26%
-57
- C4 -
1I3A
1
RNH2_ARCFU
A:
[24-211]
---------------------------------------------------------------------------------------------------------------------------------
G
I
D
E
A
G
K
G
C
V
I
G
P
L
V
V
A
G
--
V
A
C
S
D
E
D
R
L
R
K
L
G
V
K
D
S
K
K
L
S
Q
G
R
----
R
E
E
L
A
E
E
I
R
K
-
I
C
-
R
T
E
V
L
K
V
S
P
E
N
L
D
--
E
------------
R
M
A
A
K
T
I
N
E
I
L
K
E
C
Y
A
E
I
I
L
-
R
-------
L
---
K
P
E
----
I
A
Y
V
D
----
S
-
P
D
-
V
I
P
E
R
L
S
R
-------
E
L
E
------
E
I
T
G
L
-----
R
V
V
A
E
H
K
A
D
E
K
Y
P
L
V
A
A
A
S
I
I
A
---
K
V
E
R
E
R
E
I
E
R
L
K
E
K
F
G
---
D
F
G
S
G
Y
A
S
D
P
R
T
R
E
V
L
----
K
E
----
W
--
I
A
-
S
--
G
R
I
P
S
C
V
R
M
R
W
K
T
V
S
N
L
R
Q
K
----
17
PsiBlast_PDB
68.31
24%
-58
- C4 -
1IO2
-
RNH2_THEKO
A:
[3-183]
-------------------------------------------------------------------------------------------------------------------------------
I
A
G
I
D
E
A
G
R
G
P
V
I
G
P
M
V
I
A
A
V
V
V
D
E
N
S
L
P
K
L
E
E
L
K
V
R
D
S
K
K
L
T
P
K
R
R
E
K
L
F
N
E
I
L
G
V
L
D
D
-
Y
V
----
I
L
E
L
P
P
D
V
I
G
--
S
R
E
-
G
-
T
L
N
----
E
F
E
V
E
N
F
A
K
A
L
N
S
L
K
V
-----------------
K
P
D
----
V
I
Y
A
D
A
A
-
D
V
-
D
E
-
E
R
F
A
R
E
L
G
-------
E
R
L
------
N
F
E
A
------
E
V
V
A
K
H
K
A
D
D
I
F
P
V
V
S
A
A
S
I
L
A
---
K
V
T
R
D
R
A
V
E
K
L
K
E
E
Y
G
E
---
I
G
S
G
Y
P
S
D
P
R
T
R
A
F
L
----
E
N
----
Y
--
Y
R
-
E
--
H
-
G
E
F
P
P
I
V
R
K
G
W
K
T
L
K
K
I
A
E
K
--