@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1805: (2015-12-10 )
MEENMNIKQLKSKTMLGTVALVSAFSFASTNADANTYNYAVDVDYLASAEEIAQAHPASNTFPLGQCTWGVKEMATWAGNWWGNGGDWAASAASAGYTVGTQPRVGSIVCWTDGSYGHVAYVTAVDPVTNKIQVLESNYAGHQWIDNYRGWFDPQNTATPGVVSYIYPN
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10--......-----...-------20.--.......-30........40..-----......50.....------...60------...---.-....70-.....-.----.-.---80---.----.-..-.....90..--------.--------.....-----100---..-----......--------.110.-------------.------------.----.---..-----.120..-...--..130...----....140------....--...150.......----160.......---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEENM
N
I
K
Q
L
---
K
SKT
M
L
-----
G
T
V
-------
A
L
V
--
S
A
F
SFAS-TNADAN
T
Y
N
Y
A
V
D
V
-----
D
Y
LA
S
A
E
E
I
A
Q
AH------PASNT------FPL---
G
-
Q
C
TW
G
V
-
K
E
M
A
T
-
W
----A-G---N----W----W-GN-GG
D
W
A
ASAA--------S--------AGYTV-----G-----TQ-----PRV
G
S
I
--------
V
C
WTD-------------G------------S----Y---G
H
-----
V
A
Y
V
T
A-VDP--VT
N
K
I
Q
V
L----ESNYAGH------
Q
W
I
D
--NYRGWFDPQNTAT----P
G
V
V
S
YIYPN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
88.06
57%
-111
- C5 -
4CGK
6
?
B:
[284-392]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
S
------
Y
P
I
---
G
-
E
C
T
W
G
V
-
K
T
L
A
P
-
W
----
A
-
G
---
D
----
Y
----
W
-
G
N
-
G
A
Q
W
A
T
S
A
A
--------
A
--------
A
G
F
R
T
-----
G
-----
S
T
-----
P
Q
V
G
A
I
--------
A
C
W
N
D
-------------
G
------------
G
----
Y
---
G
H
-----
V
A
V
V
T
A
-
V
E
S
--
T
T
-
R
I
Q
V
S
----
E
S
N
Y
A
G
N
------
R
T
I
G
--
N
H
R
G
W
F
N
P
-
T
T
T
S
----
E
G
F
V
T
Y
I
Y
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
87.43
44%
-90
- C5 -
4CGK
7
?
A:
[42-392]
SNLT
A
Q
Q
Q
E
A
Q
K
Q
V
D
Q
I
Q
E
Q
V
S
A
I
Q
A
E
Q
S
N
L
Q
A
E
N
D
R
L
Q
A
E
S
K
K
L
E
G
E
I
T
E
L
S
K
N
I
V
S
R
N
Q
S
L
E
K
Q
A
R
S
A
Q
T
N
G
A
V
T
S
Y
I
N
T
I
V
NSKSITEAIS
R
V
A
A
M
S
E
I
V
S
A
N
N
K
M
L
E
Q
Q
K
A
D
K
K
A
I
S
E
K
Q
V
A
N
N
D
A
I
N
T
V
I
A
N
Q
Q
K
L
A
D
D
A
Q
A
L
T
T
K
Q
A
E
L
K
A
A
E
L
S
L
A
A
E
K
ATA
E
G
E
K
A
S
L
L
E
Q
K
A
A
A
E
A
E
A
R
---
A
A
A
V
A
E
-----
A
A
Y
-------
K
E
K
--
R
A
S
Q
Q
Q
S
-
V
L
A
S
A
N
T
N
L
T
A
Q
V
Q
-----
A
V
S
E
S
A
A
A
P
V
R
A
K
V
R
P
T
Y
S
T
N
A
S
S
------
Y
P
I
---
G
-
E
C
T
W
G
V
-
K
T
L
A
P
-
W
----
A
-
G
---
D
----
Y
----
W
-
G
N
-
G
A
Q
W
A
T
S
A
A
--------
A
--------
A
G
F
R
T
-----
G
-----
S
T
-----
P
Q
V
G
A
I
--------
A
C
W
N
D
-------------
G
------------
G
----
Y
---
G
H
-----
V
A
V
V
T
A
-
V
E
S
---
T
T
R
I
Q
V
S
----
E
S
N
Y
A
G
N
------
R
T
I
G
--
N
H
R
G
W
F
N
P
T
T
T
-
S
----
E
G
F
V
T
Y
I
Y
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
87.21
57%
-110
- C5 -
4CGK
5
?
A:
[284-392]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
S
------
Y
P
I
---
G
-
E
C
T
W
G
V
-
K
T
L
A
P
-
W
----
A
-
G
---
D
----
Y
----
W
-
G
N
-
G
A
Q
W
A
T
S
A
A
--------
A
--------
A
G
F
R
T
-----
G
-----
S
T
-----
P
Q
V
G
A
I
--------
A
C
W
N
D
-------------
G
------------
G
----
Y
---
G
H
-----
V
A
V
V
T
A
-
V
E
S
--
T
T
-
R
I
Q
V
S
----
E
S
N
Y
A
G
N
------
R
T
I
G
--
N
H
R
G
W
F
N
P
-
T
T
T
S
----
E
G
F
V
T
Y
I
Y
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
79.24
38%
-107
- C5 -
2K3A
-
?
A:
[43-155]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
S
G
------
S
S
A
N
L
------
Y
T
A
---
G
-
Q
C
T
W
Y
V
-
Y
D
K
V
G
G
N
----
I
-
G
---
S
----
T
----
W
-
G
N
-
A
N
N
W
A
S
A
A
S
--------
S
--------
A
G
Y
T
V
-----
N
-----
N
S
-----
P
E
A
G
S
I
--------
L
Q
S
T
A
-------------
G
------------
G
----
Y
---
G
H
-----
V
A
Y
V
E
N
-
V
N
S
---
D
G
S
V
E
V
S
----
E
M
N
Y
N
G
G
------
P
F
S
V
--
S
E
R
T
I
S
A
----
G
E
----
A
S
S
Y
N
Y
I
H
L
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
67.78
20%
-64
- C5 -
4OLK
2
?
A:
[4-167]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
A
K
T
Q
A
E
I
N
K
R
---
L
D
A
Y
A
K
-----
G
T
V
-------
D
-----------------
S
P
Y
R
I
K
K
A
T
-----
S
Y
D
P
S
F
G
V
M
E
A
G
A
------
I
D
A
D
G
------
Y
Y
H
---
A
-
Q
C
Q
D
L
I
-
T
D
Y
V
L
-
W
----
L
-
T
---
D
----
N
K
V
R
T
W
-
G
N
-
A
K
D
Q
I
K
Q
S
Y
--------
G
--------
T
G
F
K
I
-----
H
-----
E
N
K
PS
T
V
P
K
K
G
W
I
--------
A
V
F
T
S
-------------
G
SYQ---------
Q
----
W
---
G
H
-----
I
G
I
V
Y
D
-
G
G
N
---
T
S
T
F
T
I
L
----
E
Q
N
W
N
G
-------------
Y
A
N
K
K
P
T
K
R
V
D
N
Y
----
Y
G
L
T
H
F
I
E
I
P
V
K-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
67.18
46%
-122
- C5 -
2K3A
-
?
A:
[49-131]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
L
------
Y
T
A
---
G
-
Q
C
T
W
Y
V
Y
D
K
V
G
G
-
N
----
I
-
G
---
S
----
T
----
W
-
G
N
-
A
N
N
W
A
S
A
A
S
--------
S
--------
A
G
Y
T
V
-----
N
-----
N
S
-----
P
E
A
G
S
I
--------
L
Q
S
T
A
-------------
G
------------
G
----
Y
---
G
H
-----
V
A
Y
V
E
N
-
V
N
S
---
D
G
S
V
E
V
S
----
E
M
N
Y
N
G
G
------
P
F
S
V
--
S
E
R
T
I
S
A
G
E
A
S
S
Y
----
N
Y
I
H
L
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
66.66
16%
-79
- C5 -
2VOB
2
?
A:
[5-652]
---------------------------------------------------------------------------------------------------------------------------------------------Q
R
A
S
V
S
FNKPGHIPFGAVQGYAPGG
V
P
A
Y
S
NKHDHYF
S
G
E
R
N
I
E
D
N
I
---
F
F
G
F
K
Y
-----
Q
C
V
-------
E
F
A
--
R
R
W
L
L
V
R
-
K
G
L
L
L
P
D
V
N
W
A
C
H
I
-----
F
Q
L
K
E
V
R
D
A
----------
A
T
T
E
S
------
F
A
V
---
L
-
Q
V
R
N
G
T
-
T
-------------------------------------------------------------------------
T
K
-----
P
E
A
D
A
L
--------
L
V
Y
P
S
-------------
T
------------
D
----
A
NPV
G
H
-----
V
G
T
I
T
E
-
V
G
D
----
D
Y
V
C
V
A
----
D
Q
N
Y
R
F
H
------
K
W
E
S
--
S
C
A
--
Y
K
L
K
L
D
H
R
----
D
G
I
W
T
I
I
D
D
I
DAD
E
I
E
I
P
L
G
W
L
T
FPGRANRPEGAPPVALHPSLHFKEPP
K
P
Y
L
L
R
R
N
F
L
P
TESKANWLDMNN
P
A
E
R
L
F
V
E
E
FGMV
S
Y
Y
E
S
N
H
E
F
H
L
R
C
V
A
Y
G
T
Q
L
H
A
I
F
M
E
A
T
A
Q
V
I
E
S
D
E
K
L
R
L
F
AIPEEF
W
P
R
I
R
H
S
W
K
Y
QQTYI
S
G
R
F
D
F
A
F
N
NETG
E
V
K
C
FEYNADSAST
L
L
E
C
G
L
I
Q
Q
K
W
A
E
S
V
GLDKQDTRGSGFA
V
E
R
N
L
K
M
A
W
A
N
SGAT
G
R
V
H
FCVDEE
R
E
E
Q
Y
T
A
L
Y
C
M
Q
A
A
E
A
V
G
L
E
G
K
L
C
I
L
FDE
F
R
F
D
DNG
H
V
V
D
SDGVRVR
N
V
W
K
TWM
W
E
S
A
I
T
D
Y
Y
A
A
R
E
E
R
GENWKPSPKDKVRLCDLLLGDDWEILYFEPMW
K
V
I
P
S
NKAI
L
P
M
I
Y
H
N
HPEHPAILKAEYELT
D
E
L
R
K
H
G
Y
A
K
K
P
I
VN
M
I
Y
Q
Q
L
F
EKQDD
Y
Y
A
I
I
G
G
W
M
I
GDAFS
G
T
G
I
R
EP
F
A
A
V
R
I
K
T
D
K
L
PHPVTLKDIDKMAEDE----------
43
Fugue
66.53
24%
-77
- C5 -
4CT3
9
?
A:
[2-165]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
T
Q
A
E
I
N
K
R
---
L
D
A
Y
A
K
-----
G
T
V
-------
D
-----------------
S
P
Y
R
V
K
K
A
T
-----
S
Y
D
P
S
F
G
V
M
E
A
G
A
------
I
D
A
D
G
------
Y
Y
H
---
A
-
Q
Q
D
L
-
I
-
T
D
Y
V
L
-
W
----
L
-
T
---
D
NK
V
R
T
----
W
-
G
N
-
A
K
D
Q
I
K
Q
S
Y
--------
G
--------
T
G
F
K
I
-----
H
E
NKPS
T
V
-----
P
K
K
G
W
I
--------
A
V
F
T
S
-------------
G
------------
S
----
Y
EQW
G
H
-----
I
G
I
V
Y
D
-
G
G
N
---
T
S
T
F
T
I
L
----
E
Q
N
W
N
G
Y
ANK
K
P
T
K
R
V
D
--
N
Y
Y
G
---------------
L
T
H
F
I
E
I
P
V
K
A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
64.60
40%
-105
- C5 -
2LRJ
-
?
A:
[9-90]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
------
Y
T
A
---
G
-
Q
C
T
W
Y
V
Y
D
K
V
G
G
-
E
----
I
-
G
---
S
----
T
----
W
-
G
N
-
A
N
N
W
A
A
A
A
Q
--------
G
--------
A
G
F
T
V
-----
N
-----
H
T
-----
P
S
K
G
A
I
--------
L
Q
S
S
E
-------------
G
------------
P
----
F
---
G
H
-----
V
A
Y
V
E
S
-
V
N
S
---
D
G
S
V
T
I
S
----
E
M
N
Y
S
G
G
------
P
F
S
V
--
S
S
R
T
I
S
A
S
E
A
G
N
Y
----
N
Y
I
H
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
59.81
19%
-103
- C5 -
2IO8
-
GSP_ECOLI
A:
[56-154]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
---
W
-
Q
C
V
E
F
A
-
R
R
F
L
F
-
L
N
YG
V
V
-
F
---
T
----
D
----
V
-
G
M
-
A
W
E
I
F
S
L
R
F
L
R
E
VVND
N
I
--------
L
P
L
Q
A
F
P
NGS
P
-----
R
A
-----
P
V
A
G
A
L
--------
L
I
W
D
K
GGEF---------
K
------------
D
----
T
---
G
H
-----
V
A
I
I
T
Q
-
L
H
G
----
N
K
V
R
I
A
----
E
Q
N
V
I
H
S
------
P
L
P
Q
--
G
Q
Q
W
T
R
E
L
E
M
V
V
E
----
N
G
C
Y
T
L
K
D
T
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
58.72
20%
-102
* C5 *
3A2Z
-
GSP_ECOLI
A:
[55-155]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
K
---
W
-
Q
C
V
E
F
A
-
R
R
F
L
F
-
L
N
YG
V
V
-
F
---
T
----
D
----
V
-
G
M
-
A
W
E
I
F
S
L
R
F
--------
L
R
EVVND
N
I
L
P
L
Q
A
F
P
NGS
P
-----
R
A
-----
P
V
A
G
A
L
--------
L
I
W
D
K
-------------
G
GEFK--------
D
----
T
---
G
H
-----
V
A
I
I
T
Q
-
L
H
G
----
N
K
V
R
I
A
----
E
Q
N
V
I
H
S
------
P
L
P
Q
--
G
Q
Q
W
T
R
E
L
E
M
V
V
E
----
N
G
C
Y
T
L
K
D
T
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
57.98
18%
-71
- C5 -
2IO8
4
GSP_ECOLI
A:
[10-618]
----------------------------------------------------------------------------------------------------------------------------------------------------------APFGTLLGYAPGG
V
A
I
Y
S
SDYSDD
A
V
F
R
S
Y
I
D
D
E
---
Y
M
G
H
K
W
-----
Q
C
V
-------
E
F
A
--
R
R
F
L
F
L
N
-
Y
G
V
V
F
T
D
V
G
M
A
W
E
I
-----
F
S
L
R
F
L
R
E
V
V
N
----------
D
N
I
------
L
P
L
---
Q
-
A
F
P
N
G
S
-
P
R
-------------------------------------------------------------------------
A
-----
P
V
A
G
A
L
--------
L
I
W
D
K
-------------
G
------------
G
EFKD
T
---
G
H
-----
V
A
I
I
T
Q
-
L
H
G
----
N
K
V
R
I
A
----
E
Q
N
V
I
H
S
------
P
L
P
Q
--
G
Q
Q
W
T
R
E
L
E
M
V
V
E
----
N
G
C
Y
T
L
K
D
T
F
DDTTIL
G
W
M
I
QTEDTEYSLPQPEIAGELL
K
I
S
G
A
R
L
ENKGQFDGKWLDEKD
P
L
Q
N
A
Y
V
Q
A
NGQVINQDPY
H
Y
Y
T
I
T
E
S
A
E
Q
E
L
I
K
A
T
N
E
L
H
L
M
Y
L
H
A
T
D
K
V
L
K
D
D
N
L
L
A
L
F
DIPKIL
W
P
R
L
R
L
S
W
Q
R
R
R
HHMI
T
G
R
M
D
F
C
M
D
ER
G
L
K
V
YEYNADSASC
H
T
E
A
G
L
I
L
E
R
W
A
E
Q
GYKGNGFNPAEG
L
I
N
E
L
A
G
A
W
K
H
SRARP
F
V
H
I
M
Q
D
KDIEE
N
Y
H
A
Q
F
M
E
Q
A
L
H
Q
A
G
F
E
T
R
I
L
R
G
LDE
L
G
W
D
AA
G
Q
L
I
D
GEG
R
L
V
N
C
VWKTWA
W
E
T
A
F
D
Q
I
R
E
VEFAAVPIRTGHPQNEVR
L
I
D
V
L
L
RPE
V
L
V
F
EPLWTVIPGNKAI
L
P
I
L
W
S
L
F
PHHRYLLDTDFTVN
D
E
L
V
K
T
G
Y
A
V
K
P
IAGRCGSN
I
D
L
V
S
HHEEVL
D
K
T
S
G
KFAE
Q
K
N
I
Y
Q
Q
L
W
C
L
P
K
V
DG
K
Y
I
Q
V
C
T
F
T
V
GGNYG
G
T
C
L
R
G
D
ESLVIKKE
S
D
I
E
P
L
I
V
V
K
24
HHSearch
52.63
20%
-103
- C5 -
2VOB
-
?
A:
[56-155]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
---
Y
-
Q
C
V
E
F
A
-
R
R
W
L
L
-
V
----
R
K
G
L
L
L
P
----
D
----
V
-
N
W
-
A
C
H
I
F
Q
L
K
E
VRDAATT
E
S
--------
F
A
V
L
Q
V
R
N
GT
T
-----
T
K
-----
P
E
A
D
A
L
--------
L
V
Y
P
S
TDA----------
N
------------
P
----
V
---
G
H
-----
V
G
T
I
T
E
-
V
G
D
----
D
Y
V
C
V
A
----
D
Q
N
Y
R
F
H
------
K
W
E
S
--
S
C
A
Y
K
L
K
L
D
H
R
D
G
----
I
W
T
I
I
D
D
I
D
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
52.13
17%
-54
- C2 -
1DDT
-
?
?:
[200-380]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
C
I
N
L
D
W
D
V
I
---
R
D
K
T
K
T
-----
K
I
E
-------
S
L
K
E
H
G
P
I
K
N
K
M
-
S
E
S
P
N
K
T
V
S
E
E
K
A
K
-----
Q
Y
L
E
E
F
H
Q
T
A
L
E
H
------
P
E
L
S
E
------
L
K
T
V
T
G
T
-
N
P
V
F
A
G
-
A
N
Y
A
A
-
W
----
A
-
V
---
N
----
V
----
A
-
Q
V
I
D
S
E
T
A
D
N
L
E
--------
K
--------
T
T
A
A
L
-----
S
-----
I
L
-----
P
G
I
G
S
V
--------
M
G
I
A
D
-------------
G
------------
A
----
V
---
H
H
NT
E
E
I
V
A
Q
S
I
A
-
L
S
S
L
M
V
A
Q
A
I
P
L
V
GELV
D
I
G
F
A
A
Y
------
N
F
V
E
--
S
I
I
N
L
F
Q
V
V
H
N
S
Y
----
N
R
P
A
Y
S
P
G
H
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
44.52
22%
-50
* C4 *
2PNN
1
TRPV1_RAT
A:
[11-258]
-------------------------------------------------------------------------------------------------------------LYD
R
R
S
I
F
D
A
V
A
Q
SNCQELES
L
L
P
F
L
Q
R
S
KKRLTDSEFKDPETGKT
C
L
L
K
A
M
L
N
LHNGQND
T
I
A
L
L
L
D
V
A
R
K
T
D
S
L
K
Q
F
---
V
N
A
S
Y
T
DSYYK
G
Q
T
-------
A
L
H
--
I
A
I
E
R
R
N
M
T
L
V
T
L
L
V
E
N
G
A
-
D
V
-----
Q
A
A
A
N
G
D
F
F
K
K
T
K
------
G
R
P
G
F
Y
FGEL
P
L
S
L
---
A
-
A
C
T
N
Q
L
-
A
I
V
K
F
-
L
----
L
-
Q
---
N
----------------
S
W
Q
P
A
D
I
--------
S
--------
A
R
D
S
V
-----
G
-----
N
------
T
V
L
H
A
L
--------
V
E
V
A
D
-------------
N
------------
T
----
V
---
D
N
-----
T
K
F
V
T
S
M
Y
------
N
E
I
L
I
L
----
G
A
K
L
H
P
T
------
L
K
L
E
EI
T
N
R
K
G
L
T
P
L
A
L
A
A
S
S
GK
I
G
V
L
A
Y
I
L
Q
R
E
I
H------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
43.77
19%
-29
- C4 -
1ZR6
7
?
A:
[3-481]
-----------EAEFN
S
I
N
A
C
L
A
A
A
D
V
E
F
H
E
EDS
E
G
W
D
M
D
G
TAFNLRV
D
Y
D
P
A
A
I
A
I
P
RS
T
E
D
I
A
A
A
V
Q
C
G
L
D
A
G
V
Q
I
S
A
K
G
GGHSYGSYGFGGEDGHLMLELDRM
Y
R
V
S
V
D
DNN
V
A
T
I
Q
GGAR
L
G
Y
T
A
L
E
L
L
D
Q
GN
R
A
L
S
H
G
TCPAVG
V
G
G
H
V
L
G
G
G
Y
G
FATHTHGLTLDWLI
G
A
T
V
V
L
A
D
A
S
I
V
H
V
S
ET
E
N
A
D
L
F
-----
W
A
L
R
G
GGGGF
A
I
V
--
S
E
F
E
F
N
T
-
F
E
A
P
E
I
I
T
T
Y
Q
V
T
T
TWN
R
K
Q
H
V
A
G
L
K
A
L
Q
D
W
A
------
Q
N
T
M
P
------
R
E
L
---
S
-
M
R
L
E
I
N
-
A
N
A
L
N
-
W
----
E
-
G
---
N
----
F
----
F
-
G
N
-
A
K
D
L
K
K
I
L
Q
--------
P
--------
I
M
K
K
A
-----
G
-----
G
K
-------------------------------------------------------------------------------
S
T
I
S
K
L
V
----
E
T
D
W
Y
G
Q
------
I
--
N
--
T
Y
L
Y
G
A
D
L
N
I
T
Y
N
----
Y
D
V
H
E
Y
F
Y
A
N
S
L
T
A
P
RLS
D
E
A
I
Q
A
F
V
D
Y
K
F
DNSSVRPG
R
G
W
W
I
Q
WDFHGGKNSALAAVSNDETAYAHRDQL
W
L
W
Q
F
Y
D
S
I
YDYENNTSPYPESG
F
E
F
M
Q
G
F
V
A
T
IEDTLPEDR
K
G
K
Y
FNYADTTLT
K
E
E
A
Q
K
L
Y
WRGN
L
E
K
L
Q
A
I
K
A
K
Y
DPEDVFGNVVSVEPIAY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
39.06
12%
-126
- C5 -
2IM9
-
?
A:
[263-308]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-----
I
P
N
G
A
V
--------
I
E
I
I
R
-------------
P
NWDLRQQIG
T
E
L
D
----
I
---
S
H
-----
L
G
F
A
I
W
-
I
N
-----
N
E
L
F
F
R
----
Q
A
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
38.94
11%
-73
- C5 -
2HBW
3
?
A:
[104-183]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
Q
K
A
M
Q
Q
-
S
N
Y
Y
------
L
W
G
G
T
------
V
G
P
---
N
Y
D
C
S
G
L
M
-
Q
A
A
F
V
-
S
----
V
-
G
---
I
----
W
----
L
P
R
D
-
A
Y
Q
Q
E
------------
A
--------
F
T
Q
A
I
-----
T
I----
D
E
-----
L
A
P
G
D
L
--------
V
F
F
G
T
P------------
V
------------
K
----
A
---
T
H
-----
V
G
L
Y
L
G
-
D
G
C
--
Y
I
H
S
S
G
K
A
----
Q
G
R
D
G
I
G
------
I
D
I
L
--
S
E
Q
G
D
V
V
S
R
S
Y
Y
Q
----
Q
L
R
G
A
G
R
V
V
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
38.25
14%
-35
- C5 -
3M1U
8
?
A:
[279-381]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-----
M
A
E
L
G
N
R
M
M
G
Q
P
Y
------
G
W
G
G
L
------
Y
E
D
---
R
-
D
C
S
S
T
L
-
R
D
L
F
T
-
P
----
F
-
G
---
L
----
W
----
L
P
R
N
-
S
A
S
Q
A
K
--------------------
A
G
R
Y
V
-----
D
I----
A
K
-----
L
D
A
D
D
K
E
A
R
I
V
A
EG
V
P
F
M
T
-------------
L
L
W
----------
L
----
R
---
G
H
-----
I
T
L
Y
L
G
-
L
H
E
----
G
Q
A
A
M
F
----
H
N
M
W
G
I
R
------
T
H
R
G
--
G
V
E
G
R
Y
V
L
G
R
A
V
V
----
T
S
T
R
P
G
L
D
V
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
38.19
26%
-122
- C5 -
2IF6
-
?
A:
[4-50]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-----
P
Q
T
G
D
I
--------
I
F
Q
I
S
RSSQ
S
K
A
I
Q
L
A
T
H
S
------------
D
----
Y
---
S
H
-----
T
G
M
L
V
M
-
R
N
-----
K
K
P
Y
V
F
----
E
A
V
G
P
V
K
------
Y
T
P
L
--
K
Q
W
I
A
H
G
E
K
G
K
Y
V
----
V
R
R
V
E
G
G
L
S
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------