@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1817: (2015-12-11 )
MLVIILIIVLASLTVTIISYQKMTELTKSVEKQLEDNADNLSDQLTYQIEAAQKDQILTLTNQLNRMQQEIYQLLTDMRTELNQHLTESRDRSDKRLELINSNLSQSVQKMQDSNEKRLDQMRQTVEEKLEKTLQTRLQTSFETVSRQLESVNQGLGEMKTVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTVSQYEREFPTVSGSSERVEYAIKLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYELGDKVQIELYRKSLLASIRKFAKDINNKYLNPPETTNFGIMFLPTEGLYSEVVRNATFFDSLRRDENIVVAGPSTLSALLNSLSVGFKTLNIQKNANDISKILGNVKVEFGKFGGMLSKAQKQLNTASKSIDNLLTTRTNAIIRALNTVEEHQDQATTSLLNLPITEEEEINEN
Atome Classification :
(20 SA)
.........10........20........30........40........50........60.-.......70.--......--.80.......-.--90-.......-..100.......110.......120.......130.......140.......150.......160.......170...-....180.......190--........200.......210.......220.......230.-......240.......250.......260.......270.......280.......290.......300..--....---.310.......320.-------......330.......340.......350.......360...-----....370.....------------..380.......390.......400.......410.......420..----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
L
V
I
I
L
I
I
V
L
A
S
L
T
V
T
I
I
S
Y
Q
K
M
T
E
L
T
K
S
V
E
K
Q
L
EDNADNLSD
Q
L
T
Y
Q
I
EAAQKD
Q
I
L
T
L
T
N
-
Q
L
N
R
M
Q
Q
E
I
Y
--
Q
L
L
T
D
M
--
R
T
E
L
N
Q
H
L
T
E
-S--R--DRS
D
K
R
L
-
E
L
I
N
S
N
L
S
Q
S
V
Q
K
M
QDS
N
E
K
R
L
D
Q
M
R
Q
T
V
E
E
K
L
E
K
T
L
Q
T
R
L
Q
T
S
F
E
T
V
S
R
Q
L
E
S
V
N
Q
G
L
G
E
M
K
T
V
A
Q
D
V
G
T
L
N
K
V
L
SN-TKTRGILGE
L
Q
L
G
Q
I
I
---
E
D
I
M
T
V
S
Q
Y
E
R
EFPTVSGSS
E
R
V
E
Y
A
I
KLPGNGQG
D
Y
I
Y
L
PI-DSKF
P
L
E
D
Y
Y
R
L
E
D
A
Y
ELG
D
K
V
Q
I
E
L
Y
R
K
S
L
L
A
S
I
R
K
F
A
K
D
I
N
NKYLNPPETTN
F
G
I
M
F
LPTE
G
L
Y
S
E
V
V
R--N
A
T
F
---
F
D
S
LRRDE
N
I
V
V
AG
P
-------
S
T
L
S
A
L
L
N
S
L
SVG
F
K
T
L
N
IQKN
A
N
D
I
S
K
I
L
GN
V
K
V
E
F
G
K
F
G
G
-----
M
L
S
K
A
Q
K
Q
L
N
T
A
------------
S
K
S
I
D
N
L
L
T
T
R
T
N
A
I
I
R
A
L
N
T
V
E
E
H
Q
D
Q
A
T
T
S
LLNLPIT
E
E
E
EINEN----------
42
Fugue
80.04
17%
-6
* C6 *
1LGR
2
?
?:
[101-468]
-------------------
D
R
D
P
R
S
I
A
K
R
A
E
D
Y
L
R
A
--
T
G
I
A
D
T
V
L
F
G
P
E
P
---
E
F
F
L
F
D
D
I
-
R
F
G
A
S
I
S
G
S
H
--
V
A
I
D
D
I
--
E
G
A
W
N
S
S
T
K
Y
-
E
--
G
--
G
N
K
G
H
R
P
-
G
V
K
G
G
Y
F
P
V
P
P
V
---
D
S
----
A
Q
D
I
R
S
E
M
C
L
V
M
E
Q
M
G
L
V
V
E
A
H
H
H
E
V
A
T
A
G
Q
N
E
V
A
T
R
F
N
T
M
T
K
K
A
D
E
I
Q
I
Y
K
Y
V
V
H
N
V
A
H
R
F
G
K
T
A
T
F
M
P
K
P
M
F
---
G
D
--------------
N
G
S
G
M
H
C
H
M
S
L
A
K
N
G
------------
T
N
L
F
S
G
D
K
Y
A
G
L
S
------------
E
Q
A
L
Y
Y
I
G
G
V
I
K
H
A
K
A
I
N
--
A
L
A
N
P
T
T
N
S
Y
K
R
L
V
P
P
V
M
L
A
Y
S
A
R
N
R
--
S
A
S
I
RIP
V
V
A
S
P
K
A
R
R
I
E
V
R
F
P
DPAAN
P
Y
L
C
F
A
A
L
L
M
A
G
L
D
G
I
K
N
K
I
H
P
G
E
P
M
D
I
P
Q
V
A
G
S
----------------
L
E
E
A
L
N
A
L
D
L
D
------------
R
----
E
F
L
K
A
G
G
V
F
T
D
E
A
I
D
A
Y
I
A
L
R
R
E
E
D
D
R
V
R
M
T
P
H
P
V
E
F
E
L
Y
Y
S
V---------
5
PsiBlast_PDB
65.25
28%
15
- C4 -
4DVY
-
CAGA_HELPY
P:
[622-755]
------------------
S
L
R
K
R
E
H
L
E
K
E
V
E
K
K
L
E
S
K
S
---
N
K
M
E
A
K
A
Q
A
N
S
Q
K
D
E
I
F
A
L
I
N
K
E
A
N
R
D
A
R
A
I
A
YT
Q
N
L
K
G
I
--
K
R
E
L
S
D
K
L
E
K
I
S
--
K
--
D
L
K
D
----------
F
S
K
S
F
D
E
F
K
----------
E
E
T
L
--
K
A
L
K
G
S
V
K
D
L
G
I
N
P
E
W
I
S
K
-
V
E
N
L
N
A
A
L
N
E
F
K
N
F
S
K
V
T
Q
A
K
S
D
L
E
N
S
-
V
K
D
V
I
I
N
Q
K
V
T
D
K
V
D
N
---
L
N
Q
A
V
S
V
A
K
A
M
G
D
F
S
R
V
E
Q
V
L
A
D
L
K
N
F
S
K
E
Q
L
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
62.35
10%
-5
- C3 -
2YVX
5
MGTE_THET8
A:
[30-471]
---
V
S
L
Q
E
A
L
Q
E
G
D
T
R
A
L
R
E
V
L
E
E
I
H
P
Q
D
L
L
A
L
W
D
E
L
K
G
E
H
R
Y
V
V
L
T
L
L
P
K
A
K
A
A
E
V
L
S
H
L
S
-
P
E
E
Q
A
E
-------
Y
L
K
T
L
--
P
P
W
R
L
R
E
I
L
E
-
E
LS
L
--
D
D
L
A
D
A
L
-
Q
A
V
R
K
E
D
P
A
Y
F
Q
R
L
K
D
L
L
D
P
R
T
R
A
E
V
E
A
L
A
R
Y
E
E
D
E
A
G
G
L
M
T
P
E
Y
V
A
V
R
E
G
M
-
T
V
E
E
V
L
R
F
L
R
R
A
A
P
D
A
E
T
I
Y
Y
I
Y
V
V
-
D
E
K
G
R
L
K
G
V
L
S
L
R
D
L
I
V
AD
P
R
T
R
V
A
E
I
M
N
P
K
V
V
Y
V
R
T
D
T
D
Q
E
E
V
A
R
L
M
A
D
Y
---
D
F
T
V
L
P
V
V
D
E
E
G
R
L
V
G
I
V
T
V
D
D
V
L
D
V
L
E
A
E
A
T
E
D
I
H
K
L
G
A
V
D
V
P
D
L
V
Y
S
E
A
G
P
V
A
L
W
L
A
R
V
R
W
L
V
I
L
I
L
T
G
M
V
T
S
S
I
L
Q
G
F
E
S
V
L
---
E
A
V
T
A
L
A
F
Y
V
P
V
L
L
G
-------
T
G
G
N
T
G
N
Q
S
A
T
L
I
I
R
A
L
A
T
R
D
L
D
L
R
D
W
R
R
V
F
L
K
E
M
G
V
G
L
L
L
G
-----
L
T
L
S
F
L
L
V
G
K
V
Y
WDGHPLLLPVV
G
V
S
L
V
L
I
V
F
F
A
N
L
V
G
A
M
L
P
F
L
L
R
R
L
G
V
D
P
A
L
V
S
N
P
L
V
A
T
L
S
D
V
T
G
L
L
I
Y
L
S
V
A
R
L
L
L
E
46
Fugue
61.14
7%
12
- C5 -
1FIO
2
SSO1_YEAST
A:
[1-196]
-------------
M
H
D
F
V
G
F
M
N
K
I
S
Q
I
N
R
D
L
D
K
Y
D
H
T
I
N
Q
V
D
S
L
H
K
R
L
L
T
E
V
N
E
E
Q
A
S
H
L
R
H
-
S
L
D
N
F
V
A
Q
A
T
--
D
L
Q
F
K
L
--
K
N
E
I
K
S
A
Q
R
D
-
G
--
I
HD
T
N
K
Q
A
Q
A
-
E
N
S
R
Q
R
F
L
K
L
I
Q
D
Y
R
I
V
D
S
N
Y
K
E
E
N
K
E
Q
A
K
R
Q
Y
M
I
I
-------
Q
P
E
A
T
E
D
E
V
E
A
A
I
S
D
V
G
G
Q
Q
I
F
S
Q
A
L
L
E
A
K
T
A
L
A
E
-
V
Q
A
R
----
H
Q
E
L
L
K
L
E
---
K
S
M
A
E
L
T
Q
L
F
N
D
M
E
E
L
V
I
E
Q
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
60.22
27%
24
- C4 -
4DVZ
-
CAGA_HELPY
A:
[622-756]
------------------
S
L
R
K
R
E
H
L
E
K
E
V
E
K
K
L
E
S
K
S
G
N
K
-----
K
A
Q
A
N
S
Q
K
D
E
I
F
A
L
I
N
K
E
A
N
R
D
A
R
A
I
A
Y
T
Q
N
L
K
G
I
--
K
R
E
L
S
D
K
L
E
K
I
S
--
K
--
D
L
K
D
----------
F
S
K
S
F
D
E
F
K
N
-----
F
S
K
A
E
E
T
L
--
K
A
L
K
G
S
V
K
D
L
G
I
N
P
E
W
I
S
K
-
V
E
N
L
N
A
A
L
N
E
F
K
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
60.11
28%
32
- C4 -
4G0H
-
CAGA_HELPY
A:
[622-755]
------------------
S
L
R
K
R
E
H
L
E
K
E
V
E
K
K
L
E
S
K
S
--
K
N
K
M
E
A
K
A
Q
A
N
S
Q
K
D
E
I
F
A
L
I
N
K
E
A
N
R
D
A
R
A
I
A
Y
T
Q
N
L
K
G
I
--
K
R
E
L
S
D
K
L
E
K
I
S
--
K
--
D
L
K
D
----------
F
S
K
S
-----------
F
S
K
A
E
E
T
L
--
K
A
L
K
G
S
V
K
D
L
G
I
-
P
E
W
I
S
K
-
V
E
N
L
N
A
A
L
N
E
F
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
59.68
17%
13
- C5 -
4K12
-
?
B:
[3-84]
----------------------
M
D
S
E
R
D
K
A
R
K
E
V
E
E
Y
V
K
K
I
V
G
E
S
Y
A
K
S
T
K
K
R
H
T
I
T
V
A
L
V
N
-
E
L
N
N
I
K
N
E
Y
L
--
N
K
I
V
E
S
TS
E
S
E
L
Q
I
L
M
M
E
-
S
--
R
--
S
K
V
D
E
A
V
-
S
K
F
E
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
59.47
10%
8
* C5 *
1VCS
-
VTI1A_MOUSE
A:
[1-102]
--------------------
G
S
S
G
S
S
G
E
G
Y
E
Q
D
F
A
V
L
T
A
E
I
T
S
K
I
A
-
R
V
P
R
L
P
P
D
E
K
K
Q
M
V
A
-
N
V
E
K
Q
L
E
E
A
R
--
E
L
L
E
Q
M
--
D
L
E
V
R
E
I
P
P
Q
-
S
--
R
--
G
M
Y
S
N
R
M
-
R
S
Y
K
Q
E
M
G
K
L
E
T
D
F
K
R
S
R
I
A
S
G
P
S
S
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
58.32
25%
6
- C4 -
3S84
-
APOA4_HUMAN
A:
[40-159]
--------------------
Q
K
I
G
D
N
L
R
E
L
Q
Q
R
L
E
P
Y
A
D
----
Q
L
R
T
Q
V
N
T
Q
A
E
Q
L
R
R
Q
L
T
P
-
Y
A
Q
R
M
E
R
V
L
R
--
E
N
A
D
S
L
--
Q
A
S
L
R
P
H
A
D
E
-
L
--
K
--
A
K
I
D
Q
N
V
-
E
E
L
K
G
R
L
T
----
P
Y
A
D
E
F
K
V
K
I
D
---
Q
T
V
E
E
-
L
R
R
S
L
A
P
Y
A
Q
D
T
Q
E
K
L
N
H
Q
L
E
G
L
T
F
Q
M
K
K
N
A
E
E
L
K
A
R
I
S
A
S
A
E
E
L
R
-
Q
R
L
A
P
L
A
E
D
V
R
G
N
L
R
G
---
N
T
E
G
L
Q
K
S
L
A
E
L
G
G
H
L
D
Q
Q
V
E
E
F
R
R
R
V
E
P
Y
G
E
N
F
N
K
A
L
V
Q
Q
M
-
E
Q
L
R
Q
K
L
G
P
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
57.57
21%
50
- C4 -
1X79
3
RABE1_HUMAN
B:
[3-92]
---------------------------------------------------
E
T
R
D
Q
V
K
K
L
Q
L
-
M
L
R
Q
A
N
D
Q
L
E
--
K
T
M
K
D
---
K
Q
E
L
E
D
F
I
K
Q
-
S
--
S
--
E
D
S
S
H
Q
I
-
S
A
L
V
L
R
A
Q
A
S
-
E
I
L
L
E
E
L
Q
Q
G
L
S
Q
A
K
R
D
V
Q
E
Q
M
A
V
L
M
Q
S
R
E
Q
V
S
E
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
50.84
18%
118
- C4 -
2F8X
-
MAML1_HUMAN
M:
[5-59]
------------------------------------------------------------------------------------------
H
S
A
-
V
--
M
--
E
R
L
R
R
R
I
-
E
L
C
R
R
H
H
S
T
C
E
A
R
Y
E
A
V
S
P
E
R
L
E
L
E
R
Q
H
T
F
A
L
H
Q
R
C
I
Q
A
K
A
K
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
50.48
12%
33
- C5 -
2LQG
-
A:
[907-1044]
-----------------------
G
I
D
P
F
T
L
V
Q
R
L
E
H
A
A
K
Q
A
A
A
S
A
T
Q
T
I
A
A
A
Q
H
A
A
--
S
A
P
K
-
A
S
A
G
P
Q
P
L
L
V
--
Q
S
C
K
A
V
--
A
E
Q
I
P
L
L
V
Q
G
-
V
--
R
--
G
S
Q
A
Q
P
D
S
P
S
A
Q
L
A
L
I
A
A
S
Q
S
F
L
Q
P
G
G
K
M
V
A
A
A
K
A
S
V
P
T
I
Q
D
Q
A
S
A
M
Q
L
S
Q
C
A
K
N
L
G
T
A
L
A
E
L
R
T
A
A
Q
K
A
Q
E
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
50.21
47%
107
- C4 -
1BC3
2
ANXA5_RAT
A:
[9-46]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
F
D
G
R
A
D
A
E
V
L
R
K
A
M
K
G
L
G
T
D
------------
E
D
S
I
L
N
L
L
T
A
R
S
N
A
Q
R
Q
Q
I
A
E
E
F
K
T
L
F
G
R
D
L
V
N
D
M
K
S
E
L
K
G
K
F
E
K
L
I
----------
11
PsiBlast_PDB
50.11
47%
102
- C4 -
2IE7
3
ANXA5_RAT
A:
[8-45]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
F
D
G
R
A
D
A
E
V
L
R
K
A
M
K
G
L
G
T
D
------------
E
D
S
I
L
N
L
L
T
A
R
S
N
A
Q
R
Q
Q
I
A
E
E
F
K
T
L
F
G
R
D
L
V
N
D
M
K
S
E
L
T
G
K
F
E
K
L
I
----------
10
PsiBlast_PDB
49.99
47%
105
- C4 -
2IE6
3
ANXA5_RAT
A:
[8-45]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
F
D
G
R
A
D
A
E
V
L
R
K
A
M
K
G
L
G
T
D
------------
E
D
S
I
L
N
L
L
T
A
R
S
N
A
Q
R
Q
Q
I
A
E
E
F
K
T
L
F
G
R
D
L
V
N
D
M
K
S
E
L
T
G
K
F
E
K
L
I
----------
17
PsiBlast_PDB
49.94
47%
99
- C4 -
1BC1
2
ANXA5_RAT
A:
[9-46]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
F
D
G
R
A
D
A
E
V
L
R
K
A
M
K
G
L
G
T
D
------------
E
D
S
I
L
N
L
L
T
A
R
S
N
A
Q
R
Q
Q
I
A
E
E
F
K
T
L
F
G
R
D
L
V
N
D
M
K
S
E
L
K
G
K
F
E
K
L
I
----------
8
PsiBlast_PDB
49.73
47%
102
- C4 -
1N42
2
ANXA5_RAT
A:
[9-46]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
F
D
G
R
A
D
A
E
V
L
R
K
A
M
K
G
L
G
T
D
------------
E
D
S
I
L
N
L
L
T
A
R
S
N
A
Q
R
Q
Q
I
A
E
E
F
K
T
L
F
G
R
D
L
V
N
D
M
K
S
E
L
T
G
K
F
E
K
L
I
----------
19
PsiBlast_PDB
49.51
47%
99
- C4 -
2H0M
-
ANXA5_RAT
A:
[9-46]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
F
D
G
R
A
D
A
E
V
L
R
K
A
M
K
G
L
G
T
D
------------
E
D
S
I
L
N
L
L
T
A
R
S
N
A
Q
R
Q
Q
I
A
E
E
F
K
T
L
F
G
R
D
L
V
N
D
M
K
S
E
L
T
G
K
F
E
K
L
I
----------
15
PsiBlast_PDB
49.45
47%
115
- C4 -
1A8B
2
ANXA5_RAT
A:
[9-46]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
F
D
G
R
A
D
A
E
V
L
R
K
A
M
K
G
L
G
T
D
------------
E
D
S
I
L
N
L
L
T
A
R
S
N
A
Q
R
Q
Q
I
A
E
E
F
K
T
L
F
G
R
D
L
V
N
D
M
K
S
E
L
T
G
K
F
E
K
L
I
----------
9
PsiBlast_PDB
49.28
47%
102
- C4 -
1G5N
3
ANXA5_RAT
A:
[8-45]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
S
G
F
D
G
R
A
D
A
E
V
L
R
K
A
M
K
G
L
G
T
D
------------
E
D
S
I
L
N
L
L
T
A
R
S
N
A
Q
R
Q
Q
I
A
E
E
F
K
T
L
F
G
R
D
L
V
N
D
M
K
S
E
L
T
G
K
F
E
K
L
I
----------