@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1851: (2015-12-11 )
MAKSLQEMRERVCEANKSLPVHSLVKFTWGNVSEVDREAGLIVIKPSGVDYDQLTPENMVVTDLEGNIVEGDLNPSSDLPTHVQLYKAWPEVGGIVHTHSTEAVGWAQAGRDIPFYGTTHADYFYGPVPCARSLSEDEVNTAYEKETGSVIIEEFERRDLDPMAVPGIVVRNHGPFTWGKDPAQAVYHSVVLEEVAKMNRFTEQINPRVEPAPKYIMDKHYLRKHGPNAYYGQKGQEH
Atome Classification :
(20 SA)
------------....-.....10........20-...-.....30...-....-------.------------------40........50.......-----.60....-..---------------------..70-----..-----....-...80...-----.....90........100.......110---......-.-.120-..-..---------.-...130.-.....-----.-140........150.......160.......170........180----.........190.......200.---......210.......220.......230......--------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------M
A
K
S
-
L
Q
E
M
R
E
R
V
C
EANKSL
P
V
-
H
S
L
-
V
K
FTWG
N
V
S
E
-
V
DRE-------A------------------
G
L
I
V
I
KPSGVDYDQLTPEN-----
M
V
V
TDLE-G
N
---------------------
I
VE------GD-----LNPS-SDL
P
T
H
V
Q
-----
L
Y
K
AWPEVG
G
I
V
HTHSTEAV
G
W
A
QAGR----DIPFYG-T-THA--DY-FY---------G-PV
P
C
A
RS-LSEDE-----V-
N
T
-
A
YEKET
G
S
V
I
I
E
E
F
E
RRDLDPMAV
P
G
I
V
V
-RNHGPFTWGK------
D
P
A
Q
A
V
Y
H
S
V
V
L
E
E
V
A
K
M
N
R
F
T
E
---
Q
INPRVEPA
P
K
Y
I
M
D
K
H
Y
L
R
K
HGPNAYYGQKGQEH--------
1
PsiBlast_PDB
99.37
55%
-74
- C3 -
1JDI
1
ARAD_ECOLI
A:
[2-223]
-----------------
L
E
D
L
K
R
Q
V
L
E
A
N
L
A
L
P
K
-
H
N
L
-
V
T
L
T
W
G
N
V
S
A
-
V
D
R
E
-------
R
------------------
G
V
F
V
I
K
P
S
G
V
D
Y
S
I
M
T
A
D
D
-----
M
V
V
V
S
I
E
T
G
E
---------------------
V
V
E
------
G
A
-----
K
K
P
S
-
S
D
T
P
T
H
R
L
-----
L
Y
Q
A
F
P
S
I
G
G
I
V
H
T
H
S
R
H
A
T
I
W
A
Q
A
G
Q
----
S
I
P
A
T
G
-
T
-
T
H
A
--
D
Y
-
F
Y
---------
G
-
T
I
P
C
T
R
K
-
M
T
D
A
E
-----
I
-
N
G
-
E
Y
E
W
E
T
G
N
V
I
V
E
T
F
E
K
Q
G
I
D
A
A
Q
M
P
G
V
L
V
-
H
S
H
G
P
F
A
W
G
K
------
N
A
E
D
A
V
H
N
A
I
V
L
E
E
V
A
Y
M
G
I
F
C
R
---
Q
L
A
P
Q
L
P
D
M
Q
Q
T
L
L
N
K
H
Y
L
R
K
H
---------------------
21
PsiBlast_CBE
99.30
55%
-73
- C3 -
1JDI
5
ARAD_ECOLI
F:
[2-223]
-----------------
L
E
D
L
K
R
Q
V
L
E
A
N
L
A
L
P
K
-
H
N
L
-
V
T
L
T
W
G
N
V
S
A
-
V
D
R
E
-------
R
------------------
G
V
F
V
I
K
P
S
G
V
D
Y
S
I
M
T
A
D
D
-----
M
V
V
V
S
I
E
T
G
E
---------------------
V
V
E
------
G
A
-----
K
K
P
S
-
S
D
T
P
T
H
R
L
-----
L
Y
Q
A
F
P
S
I
G
G
I
V
H
T
H
S
R
H
A
T
I
W
A
Q
A
G
Q
----
S
I
P
A
T
G
-
T
-
T
H
A
--
D
Y
-
F
Y
---------
G
-
T
I
P
C
T
R
K
-
M
T
D
A
E
-----
I
-
N
G
-
E
Y
E
W
E
T
G
N
V
I
V
E
T
F
E
K
Q
G
I
D
A
A
Q
M
P
G
V
L
V
-
H
S
H
G
P
F
A
W
G
K
------
N
A
E
D
A
V
H
N
A
I
V
L
E
E
V
A
Y
M
G
I
F
C
R
---
Q
L
A
P
Q
L
P
D
M
Q
Q
T
L
L
N
K
H
Y
L
R
K
H
---------------------
58
Fugue
99.19
54%
-73
- C3 -
1JDI
1
ARAD_ECOLI
A:
[1-223]
---------------
M
-
L
E
D
L
K
R
Q
V
L
E
A
N
L
A
L
P
K
-
H
N
L
-
V
T
L
T
W
G
N
V
S
A
-
V
D
R
E
-------
R
------------------
G
V
F
V
I
K
P
S
G
V
D
Y
S
I
M
T
A
D
D
-----
M
V
V
V
S
I
E
T
G
E
---------------------
V
V
E
------
G
A
-----
K
K
P
S
-
S
D
T
P
T
H
R
L
-----
L
Y
Q
A
F
P
S
I
G
G
I
V
H
T
H
S
R
H
A
T
I
W
A
Q
A
G
Q
----
S
I
P
A
T
G
-
T
-
T
H
A
--
D
Y
-
F
Y
---------
G
-
T
I
P
C
T
R
K
-
M
T
D
A
E
-----
I
-
N
G
-
E
Y
E
W
E
T
G
N
V
I
V
E
T
F
E
K
Q
G
I
D
A
A
Q
M
P
G
V
L
V
-
H
S
H
G
P
F
A
W
G
K
------
N
A
E
D
A
V
H
N
A
I
V
L
E
E
V
A
Y
M
G
I
F
C
R
---
Q
L
A
P
Q
L
P
D
M
Q
Q
T
L
L
N
K
H
Y
L
R
K
H
---------------------
57
Fugue
99.19
54%
-73
- C3 -
1JDI
1
ARAD_ECOLI
A:
[1-223]
---------------
M
-
L
E
D
L
K
R
Q
V
L
E
A
N
L
A
L
P
K
-
H
N
L
-
V
T
L
T
W
G
N
V
S
A
-
V
D
R
E
-------
R
------------------
G
V
F
V
I
K
P
S
G
V
D
Y
S
I
M
T
A
D
D
-----
M
V
V
V
S
I
E
T
G
E
---------------------
V
V
E
------
G
A
-----
K
K
P
S
-
S
D
T
P
T
H
R
L
-----
L
Y
Q
A
F
P
S
I
G
G
I
V
H
T
H
S
R
H
A
T
I
W
A
Q
A
G
Q
----
S
I
P
A
T
G
-
T
-
T
H
A
--
D
Y
-
F
Y
---------
G
-
T
I
P
C
T
R
K
-
M
T
D
A
E
-----
I
-
N
G
-
E
Y
E
W
E
T
G
N
V
I
V
E
T
F
E
K
Q
G
I
D
A
A
Q
M
P
G
V
L
V
-
H
S
H
G
P
F
A
W
G
K
------
N
A
E
D
A
V
H
N
A
I
V
L
E
E
V
A
Y
M
G
I
F
C
R
---
Q
L
A
P
Q
L
P
D
M
Q
Q
T
L
L
N
K
H
Y
L
R
K
H
---------------------
26
PsiBlast_CBE
98.82
54%
-71
- C3 -
1K0W
5
ARAD_ECOLI
F:
[2-223]
-----------------
L
E
D
L
K
R
Q
V
L
E
A
N
L
A
L
P
K
-
H
N
L
-
V
T
L
T
W
G
N
V
S
A
-
V
D
R
E
-------
R
------------------
G
V
F
V
I
K
P
S
G
V
D
Y
S
I
M
T
A
D
D
-----
M
V
V
V
S
I
E
T
G
E
---------------------
V
V
E
------
G
A
-----
K
K
P
S
-
S
D
T
P
T
H
R
L
-----
L
Y
Q
A
F
P
S
I
G
G
I
V
H
T
H
S
R
H
A
T
I
W
A
Q
A
G
Q
----
S
I
P
A
T
G
-
T
-
T
H
A
--
N
Y
-
F
Y
---------
G
-
T
I
P
C
T
R
K
-
M
T
D
A
E
-----
I
-
N
G
-
E
Y
E
W
E
T
G
N
V
I
V
E
T
F
E
K
Q
G
I
D
A
A
Q
M
P
G
V
L
V
-
H
S
H
G
P
F
A
W
G
K
------
N
A
E
D
A
V
H
N
A
I
V
L
E
E
V
A
Y
M
G
I
F
C
R
---
Q
L
A
P
Q
L
P
D
M
Q
Q
T
L
L
N
K
H
Y
L
R
K
H
---------------------
45
HHSearch
98.73
55%
-71
- C3 -
1K0W
1
ARAD_ECOLI
A:
[2-223]
-----------------
L
E
D
L
K
R
Q
V
L
E
A
N
L
A
L
P
K
-
H
N
L
-
V
T
L
T
W
G
N
V
S
A
-
V
D
R
E
-------
R
------------------
G
V
F
V
I
K
P
S
G
V
D
Y
S
I
M
T
A
D
D
-----
M
V
V
V
S
I
E
T
G
E
---------------------
V
V
E
------
G
A
-----
K
K
P
S
-
S
D
T
P
T
H
R
L
-----
L
Y
Q
A
F
P
S
I
G
G
I
V
H
T
H
S
R
H
A
T
I
W
A
Q
A
G
Q
----
S
I
P
A
T
G
-
T
-
T
H
A
--
N
Y
-
F
Y
---------
G
-
T
I
P
C
T
R
K
-
M
T
D
A
E
-----
I
-
N
G
-
E
Y
E
W
E
T
G
N
V
I
V
E
T
F
E
K
Q
G
I
D
A
A
Q
M
P
G
V
L
V
-
H
S
H
G
P
F
A
W
G
K
------
N
A
E
D
A
V
H
N
A
I
V
L
E
E
V
A
Y
M
G
I
F
C
R
---
Q
L
A
P
Q
L
P
D
M
Q
Q
T
L
L
N
K
H
Y
L
R
K
H
---------------------
2
PsiBlast_PDB
98.36
54%
-71
- C3 -
1K0W
1
ARAD_ECOLI
A:
[2-223]
-----------------
L
E
D
L
K
R
Q
V
L
E
A
N
L
A
L
P
K
-
H
N
L
-
V
T
L
T
W
G
N
V
S
A
-
V
D
R
E
-------
R
------------------
G
V
F
V
I
K
P
S
G
V
D
Y
S
I
M
T
A
D
D
-----
M
V
V
V
S
I
E
T
G
E
---------------------
V
V
E
------
G
A
-----
K
K
P
S
-
S
D
T
P
T
H
R
L
-----
L
Y
Q
A
F
P
S
I
G
G
I
V
H
T
H
S
R
H
A
T
I
W
A
Q
A
G
Q
----
S
I
P
A
T
G
-
T
-
T
H
A
--
N
Y
-
F
Y
---------
G
-
T
I
P
C
T
R
K
-
M
T
D
A
E
-----
I
-
N
G
-
E
Y
E
W
E
T
G
N
V
I
V
E
T
F
E
K
Q
G
I
D
A
A
Q
M
P
G
V
L
V
-
H
S
H
G
P
F
A
W
G
K
------
N
A
E
D
A
V
H
N
A
I
V
L
E
E
V
A
Y
M
G
I
F
C
R
---
Q
L
A
P
Q
L
P
D
M
Q
Q
T
L
L
N
K
H
Y
L
R
K
H
---------------------
46
HHSearch
71.73
19%
-70
* C3 *
1E4C
3
FUCA_ECOLI
P:
[2-206]
---------------
E
-
R
N
K
L
A
R
Q
I
I
D
T
C
L
E
M
T
R
-
L
G
L
-
N
Q
G
T
A
G
N
V
S
V
-
R
Y
Q
---------------------------
D
G
M
L
I
T
P
T
G
I
P
Y
E
K
L
T
E
S
H
-----
I
V
F
I
D
G
N
-
G
K
---------------------
H
E
E
------
G
------
K
L
P
Q
-
S
E
W
R
F
H
M
A
-----
A
Y
Q
S
R
P
D
A
N
A
V
V
H
N
H
A
V
H
C
T
A
V
S
I
L
N
R
----
S
I
P
A
I
--
H
-
Y
M
I
--
A
A
-
A
G
G--------
N
-
S
I
P
C
A
P
Y
-
A
T
F
----------
G
-
T
R
--
E
L
S
E
H
V
A
L
A
L
K
N
-------
R
K
A
T
L
L
-
Q
H
H
G
L
I
A
C
E
V
------
N
L
E
K
A
L
W
L
A
H
E
V
E
V
L
A
Q
L
Y
L
T
T
L
---
A
I
T
D
P
V
P
V
L
S
D
E
E
I
A
V
V
----
L
E
K
F
------------------
52
HHSearch
70.10
27%
-62
- C3 -
2IRP
2
MTNB_AQUAE
A:
[7-207]
--------------
K
K
-
F
S
E
K
V
E
E
I
I
E
A
G
R
I
L
H
S
-
R
G
W
-
V
P
A
T
S
G
N
I
S
A
-
K
V
S
E
--------------------------
E
Y
I
A
I
T
A
S
G
K
H
K
G
K
L
T
P
E
D
-----
I
L
L
I
D
Y
E
-
G
R
---------------------
P
V
G
-------
G
-----
G
K
P
S
-
A
E
T
L
L
H
T
T
-----
V
Y
K
L
F
P
E
V
N
A
V
V
H
T
H
S
P
N
A
T
V
I
S
I
V
E
K
K---
D
F
V
E
L
E
-
D
-
Y
E
L
--
L
K
-
A
F
PDIHTHEVK
I
-
K
I
P
I
F
P
N
-
E
-
Q
----------
N
-
I
P
--
L
L
A
K
E
V
E
N
Y
F
K
T
S
----
E
D
K
Y
G
F
L
I
-
R
G
H
G
L
Y
T
W
G
R
------
S
M
E
E
A
L
I
H
T
E
A
L
E
F
I
F
E
C
E
L
K
L
L
---
S
F
H
----------------------------------------
48
HHSearch
68.82
19%
-54
- C3 -
2Z7B
1
?
A:
[36-248]
--------------
T
M
-
R
R
K
V
F
E
E
L
V
T
A
T
K
I
L
L
N
-
E
G
I
-
M
D
-
T
F
G
H
I
S
A
-
R
D
P
E
-------
D
P-----------------
A
S
F
F
L
A
-
Q
K
L
A
P
S
L
I
T
V
D
D
-----
I
Q
R
F
N
L
D
-
G
E
---------------------
T
S
D
-------------
N
R
P
S
Y
L
E
R
Y
I
H
S
E
-----
I
Y
K
T
R
P
D
V
Q
C
V
L
H
T
H
S
P
A
V
L
P
Y
C
F
V
D
T
----
P
L
R
P
V
--
T
-
H
M
G
--
A
--
F
I
---------
G
E
S
V
P
V
Y
E
I
-
R
D
K
H
G
DETDL
F
-
G
G
-
S
--
P
D
V
C
A
D
I
A
E
S
L
G
S
-------
Q
T
V
V
L
M
-
A
R
H
G
V
V
N
V
G
K
------
S
V
R
E
V
V
F
R
A
F
Y
L
E
Q
E
A
A
A
L
T
A
G
L
---
K
I
G
N
V
-
K
Y
L
S
P
G
E
I
K
T
A
G
K
L
V
G
A
Q
I
D
R
G
W
N
H
W
S
Q
R
--------
49
HHSearch
67.44
15%
-55
- C3 -
2OPI
1
?
A:
[2-203]
---------------
I
-
T
D
E
H
I
E
L
F
L
A
Q
A
H
R
Y
G
D
-
A
K
L
-
M
L
C
S
S
G
N
L
S
W
-
R
I
G
---------------------------
E
E
A
L
I
S
G
T
G
S
W
V
P
T
L
A
K
E
K
-----
V
S
I
C
N
I
A
-
S
G
---------------------
T
P
T
------
N
G
-----
V
K
P
S
-
M
E
S
T
F
H
L
G
-----
V
L
R
E
R
P
D
V
N
V
V
L
H
F
Q
S
E
Y
A
T
A
I
S
C
M
K
N
----
K
P
T
N
F
N
V
T
-
A
E
I
--
P
C
H
V
G
---------
S
-
E
I
P
V
I
P
Y
-
Y
R
P
----------
G
-
S
--
P
E
L
A
K
A
V
V
E
A
M
L
K
-------
H
N
S
V
L
L
-
T
N
H
G
Q
V
V
C
G
K
------
D
F
D
Q
V
Y
E
R
A
T
F
F
E
M
A
C
R
I
I
V
Q
S
G
-----
G
D
Y
-
S
V
L
T
P
E
E
I
E
D
L
E
-------------------------
5
PsiBlast_PDB
65.26
30%
-54
- C3 -
2IRP
1
MTNB_AQUAE
A:
[5-194]
------------
L
F
K
K
-
F
S
E
K
V
E
E
I
I
E
A
G
R
I
L
H
S
-
R
G
W
-
V
P
A
T
S
G
N
I
S
A
-
K
V
S
E
-------
E
-------------------
Y
I
A
I
T
A
S
G
K
H
K
G
K
L
T
P
E
D
-----
I
L
L
I
D
Y
E
-
G
R
---------------------
P
V
G
------
G
G
------
K
P
S
-
A
E
T
L
L
H
T
T
-----
V
Y
K
L
F
P
E
V
N
A
V
V
H
T
H
S
P
N
A
T
V
I
S
I
V
E
K
KD
F
V
E
L
E
D
Y
E
-
L
-
L
K
A
F
P
D
I
-
H
T
---------
H
-
E
V
K
I
K
I
P
-
I
F
P
N
E
-----
Q
-
N
I
P
L
L
A
K
E
-----
V
E
N
Y
F
K
T
S
E
D
K
Y
---
G
F
L
I
-
R
G
H
G
L
Y
T
W
G
R
------
S
M
E
E
A
L
I
H
T
E
A
L
E
F
I
F
E
C
E
L
K
L
L
---
S
F
H
----------------------------------------
62
Fugue
64.95
17%
-34
- C3 -
2Z7B
1
?
A:
[34-270]
-------------
S
F
T
M
R
R
K
V
F
E
E
L
V
T
A
T
K
I
L
L
N
-
E
G
I
M
D
T
F
--
G
H
I
S
A
R
D
P
E
D
-------
P
------------------
A
S
F
F
L
A
Q
-
K
L
A
P
S
L
I
T
V
D
D
-----
I
Q
R
F
N
L
D
-
G
E
---------------------
T
S
D
------
N
R
-----
P
S
Y
L
-
E
-
R
Y
I
H
S
E
-----
I
Y
K
T
R
P
D
V
Q
C
V
L
H
T
H
S
P
A
V
L
P
Y
C
F
V
D
T
----
P
L
R
P
V
T
-
H
M
G
A
F
--
I
G
-
E
S
---------
V
-
P
V
Y
E
I
R
D
-
K
H
G
D
E
-----
T
D
L
F
-
G
G
S
P
D
V
C
A
D
I
A
E
S
L
G
S
Q
T
--------
V
V
L
M
A
R
H
G
V
V
N
V
G
K
------
S
V
R
E
V
V
F
R
A
F
Y
L
E
Q
E
A
A
A
L
T
A
G
L
---
K
I
G
N
V
K
Y
L
S
P
G
E
I
K
T
A
G
--
K
L
V
G
A
Q
I
D
R
G
W
N
H
W
S
Q
R
L
R
Q
A
GLA
50
HHSearch
64.52
23%
-68
- C3 -
2FK5
1
?
A:
[3-193]
------------------
A
R
L
Y
A
A
F
R
Q
V
G
E
D
L
F
A
-
Q
G
L
-
I
S
A
T
A
G
N
F
S
V
-
R
T
K
---------------------------
G
G
F
L
I
T
K
S
G
V
Q
K
A
R
L
T
P
E
D
-----
L
L
E
V
P
L
E
-
G
P
---------------------
I
P
E
------
G
--------
A
S
-
V
E
S
V
V
H
R
E
-----
V
Y
R
-
R
T
G
A
R
A
L
V
H
A
H
P
R
V
A
V
A
L
S
F
H
L
S
----
R
L
R
P
L
--
D
-
L
E
G
--
Q
H
-
Y
L
---------
K
-
E
V
P
V
L
A
P
K
T
V
S
----------
A
-
T
E
--
E
A
A
L
S
V
A
E
A
L
R
E
-------
H
R
A
C
L
L
-
R
G
H
G
A
F
A
V
G
L
K
EA
P
E
E
A
L
L
E
A
Y
G
L
M
T
T
L
E
E
S
A
Q
I
L
L
Y
H
R
---
L
W
Q
G
A
G
P
A
L
----------------------------------
47
HHSearch
63.98
16%
-54
- C3 -
3OCR
-
?
A:
[28-235]
-------------
S
P
Q
-
E
W
E
V
R
V
K
L
A
A
A
Y
R
L
A
A
L
-
K
R
W
-
T
D
H
I
Y
T
H
F
S
A
-
R
V
P
G
P------
D
------------------
E
H
F
L
I
N
A
F
G
L
L
F
D
E
I
T
A
S
N
-----
L
V
K
V
D
I
D
-
G
T
---------------------
I
V
D
------
D
P
TGL--
G
I
N
Y
-
A
G
Y
V
I
H
S
A
-----
I
H
A
A
R
H
D
L
Q
A
V
L
H
T
H
T
R
D
G
I
A
V
S
A
Q
K
D
----
G
L
L
P
I
--
S
-
Q
H
S
--
I
A
-
F
S
---------
G
-
R
V
A
Y
H
G
Y
-
E
G
I
----------
A
-
L
D
-
L
S
E
R
E
R
L
V
A
D
L
G
D
-------
K
S
V
M
I
L
-
R
N
H
G
L
L
T
G
G
V
------
S
V
E
H
A
I
Q
Q
L
H
A
L
E
Y
A
C
N
I
Q
I
A
A
Q
---
S
A
G
N
A
E
L
V
F
P
P
R
E
V
I
A
K
V
E
E
Q
A
K
A
I
G
N
G
P
G
V
A
R
H
W
--------
12
PsiBlast_PDB
62.68
22%
-56
- C3 -
4XXF
1
?
A:
[59-226]
------------------------------------------------------------------------------------
V
N
P
F
G
L
A
F
R
L
M
T
V
S
D
-----
L
I
L
V
N
Q
E
-
G
T
---------------------
V
I
G
------
G
G
K
EGRR
I
V
N
L
-
A
G
F
M
I
H
S
A
-----
I
H
K
A
R
P
E
V
Q
A
I
C
H
S
H
S
T
Y
G
K
A
F
S
S
L
G
K
----
P
L
A
I
T
--
T
-
Q
D
S
--
C
A
-
F
Y
---------
G
-
D
V
A
L
L
G
D
--------------------
E
S
G
T
I
A
V
A
L
Q
Q
K
K
--------
A
I
I
L
-
Q
N
H
G
L
L
T
V
G
T
------
T
I
D
S
A
V
A
W
F
I
M
L
E
K
Q
C
Q
V
Q
L
L
A
D
A
A
G
Q
T
I
P
I
D
E
P
Q
A
A
F
T
F
K
E
L
G
H
E
Q
A
G
Y
F
Q
A
S
P
Y
F
Q
V
I
E
--------
54
HHSearch
61.29
18%
-52
- C3 -
3M4R
2
?
A:
[12-216]
---------------
K
-
F
D
S
D
I
D
E
V
V
Y
G
S
R
L
I
G
S
D
P
D
L
-
V
L
-
G
G
G
N
T
S
V
-
K
T
T
E
R
D
HAG
R
I
I
------------------
S
V
L
R
V
K
N
S
G
S
N
L
G
T
I
D
S
R
G
-----
F
T
G
I
R
M
D
-
D
A
L
A
A
A
KIDKMT
D
E
A
M
V
D
Y
L
K
K
S
M
V
N
P-----
S
E
-----
P
S
P
S
-
V
E
T
F
L
H
A
F
-----
L
-----
P
Y
K
F
V
M
H
S
H
A
D
A
I
L
S
I
T
N
T
------
D
L
P
S
-----
D
Q
I
--
A
K
-
I
L
---------
G
-
N
V
V
V
L
P
Y
-
I
P
P
----------
G
-
F
---
T
L
A
K
E
V
M
N
C
F
K
K
------
G
I
D
G
I
V
L
-
R
K
H
G
L
L
T
F
G
D
------
T
G
K
E
A
Y
D
R
H
I
N
I
V
S
R
A
E
N
F
I
R
------------------------------------------------
3
PsiBlast_PDB
58.37
35%
-70
- C3 -
4C24
4
?
A:
[4-115]
------------
M
A
S
S
---
D
V
K
Q
E
L
I
K
Y
G
K
K
L
V
E
-
T
D
L
-
T
K
G
T
G
G
N
L
S
V
-
F
D
R
E
-------
K
------------------
Q
L
M
A
I
T
P
S
G
I
D
F
F
E
I
K
E
S
D
-----
I
V
V
M
D
I
N
-
G
N
---------------------
V
V
E
------
G
E
-----
R
L
P
S
-
S
E
W
Y
M
H
L
I
-----
Q
Y
Q
T
R
D
D
I
D
A
I
I
H
A
H
T
T
Y
A
T
V
L
A
C
L
R
E
----
P
L
P
A
S
H
-
Y
-
M
I
A
--
V
A
-
G
K
---------
D
-
V
R
V
A
E
Y
A
-
T
Y
G
T
K
-----
E
-
L
A
-
V
N
A
A
K
A
M
E
G
R
R
A
V
L
L
A
N
H
G
I
L
A
G
A
Q
N
L
L
N
-
A
F
N
I
V
E
E
V
E
Y
------
C
A
K
I
Y
C
L
A
K
N
F
G
E
P
V
V
L
P
D
E
E
M
E
---
L
M
A
E
K
F
K
------------------------------------
4
PsiBlast_PDB
57.72
35%
-73
- C3 -
4C25
5
?
A:
[4-115]
------------
M
A
S
S
---
D
V
K
Q
E
L
I
K
Y
G
K
K
L
V
E
-
T
D
L
-
T
K
G
T
G
G
N
L
S
V
-
F
D
R
E
-------
K
------------------
Q
L
M
A
I
T
P
S
G
I
D
F
F
E
I
K
E
S
D
-----
I
V
V
M
D
I
N
-
G
N
---------------------
V
V
E
------
G
E
-----
R
L
P
S
-
S
E
W
Y
M
H
L
I
-----
Q
Y
Q
T
R
D
D
I
D
A
I
I
H
A
H
T
T
Y
A
T
V
L
A
C
L
R
E
----
P
L
P
A
S
H
-
Y
-
M
I
A
--
V
A
-
G
K
---------
D
-
V
R
V
A
E
Y
A
-
T
Y
G
T
K
-----
E
-
L
A
-
V
N
A
A
K
A
M
E
G
R
R
A
V
L
L
A
N
H
G
I
L
A
G
A
Q
N
L
L
N
-
A
F
N
I
V
E
E
V
E
Y
------
C
A
K
I
Y
C
L
A
K
N
F
G
E
P
V
V
L
P
D
E
E
M
E
---
L
M
A
E
K
F
K
F
-----------------------------------
61
Fugue
56.32
11%
-39
- C3 -
1GT7
-
RHAD_ECOLI
A:
[1-274]
MQNITQS
W
F
V
Q
G
M
I
K
A
-
T
T
D
A
W
L
K
--
G
W
D
E
R
N
G
G
-
N
L
T
-
L
R
L
D
D
A
D
I
A
P
-
Y
H
D
N
-------
F
HQQP
R
Y
I
P
L
SQPMPLLAN
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
AAN
L
G
I
V
K
V
D
S
D
-
G
A
---------------------
G
Y
H
ILWGLT
N
E
-----
A
V
P
T
-
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
-------
E
N
D
T
-
A
-
V
F
T
--
R
Q
-
L
W
---------
E
-
G
S
T
E
C
L
V
-
V
F
P
D
G
-----
V
-
G
I
-
L
P
W
M
V
P
G
T
D
E
I
G
Q
A
T
A
Q
E
M
Q
K
H
--
S
L
V
L
W
-
P
F
H
G
V
F
G
S
G
P
------
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
---
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
---
A
S
A
L
A
L
--------