@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1981: (2015-12-12 )
MNKSKVVLAVCVAGISFLAAMNSEIDSVSANAVMNSNDISQTSNIIISSEKISPYVIEFVTQQESNNITSYARFLQSQEEENFSTVKFDFTQAEFYDENGNLVDKDTVMKTVRPEKLLARSVGTSGGTWSSGSGYSVCKGMRVSGNAGLVGLQSSYYVDFQKVQGGYNRLDRVYGATVDGAGTWTFLANGVFRGSEAPGASAYGGIEGQWSVSPGFGLPTGTSTKYLYFRVGNDTFCLDTNF
Atome Classification :
(20 SA)
----------------------------.........10........20........30..----....------------..40........50.....-------.--..60.-----.......70---.------.....-----..80........----90----.-----........100--...--...--.110...----....120.......130.......140...---------....150.-......160.......170-----..--------....---.180------------------........190..-------......200-----------....-....210.------...-...220....----------...230-........240---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------MNKS
K
V
V
L
A
V
C
V
A
G
I
S
F
L
A
A
M
N
SEIDSVSAN
A
V
----MNSN------------DISQTS
N
I
I
I
SSEKIS
P
Y
V
-------
I
--
E
F
VTQ-----QESN
N
I
T
S
Y
---
A
------
R
F
L
Q
S
-----
Q
E
EENF
S
T
V
K
F
D
----
F
-----
T
-----
Q
A
E
F
YDENGNL--V
D
K
--
D
T
V
--
M
KTV
R
P
E
----
K
L
L
A
R
SVGTSGGTWSSGSGY
S
V
CK
G
M
R
VSG---------NA
G
L
V
GLQ-S
S
Y
Y
V
D
F
Q
K
V
Q
G
G
Y
N
R
L
D
R
-----
V
Y--------GATV---DGA-------------------
G
T
W
T
F
LANG-VFR-------GSEAPGAS------------AYGG-IE
G
Q
W
SVS------PGF-GLPTGTS
T
K
Y
----------
L
Y
F
R
V--GN
D
T
F
C
LDTNF---
32
Fugue
93.48
20%
-51
- C4 -
1TL2
5
TAL2_TACTR
A:
[2-236]
-----------------------------
G
G
E
S
M
L
R
G
V
Y
Q
D
K
F
Y
Q
G
T
Y
P
Q
N
K
N
D
N
W
L
A
R
A
T
----
L
I
G
K
------------
G
G
W
S
N
F
K
F
L
F
L
S
P
G
G
E
L
Y
G
-------
V
L
N
D
K
I
Y
K
G
TPPT
H
D
N
D
N
W
M
G
R
---
A
------
K
K
I
G
N
-----
G
G
W
N
Q
F
Q
F
L
F
F
D
----------------------
P
N
G
Y
L
Y
A
V
S
K
--
D
K
L
--
Y
K
A
S
P
P
Q
SDTD
N
W
I
A
R
A
T
E
V
G
S
G
G
W
S
G
------
F
K
F
L
F
F
H
P
---------
N
G
Y
L
Y
A
V
H
G
Q
Q
F
Y
K
A
L
P
P
V
S
N
Q
D
N
W
L
A
R
-----
A
T
--------
K
I
G
Q
---
G
G
W
-------------------
D
T
F
K
F
L
F
F
---------------
S
S
V
G
T
------------
L
F
G
V
-
Q
G
G
K
F
Y
E
D
YP----
P
S
Y
-
A
Y
D
N
W
L
A
R
A
K
----------
L
I
G
N
G
--
G
W
D
D
F
R
F
L
F
-
F
---
31
Fugue
76.84
15%
-39
- C5 -
4INO
-
?
A:
[1-302]
-------------Q
E
V
K
V
K
D
YF
G
E
Q
T
I
K
L
P
V
S
K
I
I
Y
L
G
S
F
A
E
V
P
A
M
F
H
T
W
D
R
V
V
G
I
S
D
Y
A
F
K
S
D
I
V
K
A
T
------------
L
K
D
P
E
R
I
K
P
M
S
S
D
H
A
A
A
L
N
-------
V
--
E
L
L
K
K
-----
L
S
P
D
L
V
V
T
F
VGN
P
------
K
A
V
E
H
-----
A
K
K
F
G
I
S
F
L
S
F
Q
EKT
I
A
-----
E
-----
V
M
E
D
I
D
T
Q
A
K
A
--
L
E
V
--
D
A
S
--
K
K
L
A
K
M
Q
----
E
T
L
D
F
I
A
E
R
L
K
G
V
K
K
K
K
G
V
E
L
F
H
K
A
N
K
I
S
G
H
QA
L
D
S
D
I
L
E
K
G
G
I
D
N
F
-
G
L
K
Y
V
K
F
G
R
A
D
I
S
V
E
K
I
V
K
E
NPE
I
I
F
I
W
WISPLS
P
E
D
V
L
N
N
P
K
F
-------------------
A
T
I
K
A
I
K
N
K
Q
V
Y
K
L
P
TMDIG
G
P
R
A
P
L
I
S
------------
L
F
I
A
-
L
K
A
H
---
P
------
E
A
F
K
G
V
D
I
N
A
I
V
K
D
----------
Y
Y
K
V
V
FD
L
N
D
A
E
V
E
P
F
L
W
H--
27
Fugue
62.35
13%
-8
- C3 -
2A4H
-
?
A:
[53-178]
-----------------------------------------------------------------
M
A
S
H
------------
H
H
H
H
H
L
D
Q
Q
P
A
A
Q
R
T
Y
A
K
A
-------
I
--
L
E
V
C
T
-----
C
K
F
R
A
Y
P
Q
I
---
Q
------
A
F
I
Q
S
-----
G
R
P
A
K
F
P
N
L
Q
I
K
----
Y
-----
V
RGL
D
P
V
V
K
L
L
D
A
S
G
K
V
--
Q
E
T
--
L
S
I
TK
W
N
T
D
T
V
E
----
E
F
F
E
T
H
L
A
K
D
G
A
---
G
K
N
S
Y
S
V
V
E
D
A
D
G
D
D
---------
D
E
D
Y
L
R
T
N
-
R
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
61.49
14%
-31
- C2 -
3QS7
1
FLT3_HUMAN
E:
[56-411]
A
A
V
E
V
D
V
S
A
S
I
T
L
Q
V
L
V
DAPGN
I
S
C
L
W
V
F
K
H
S
S
L
N
C
Q
P
H
F
G
V
V
S
M
V
I
L
K
M
T
E
T
Q
A
G
E
Y
L
L
F
----
I
Q
S
T
------------
N
Y
T
I
L
F
T
V
S
I
R
T
L
R
R
P
Y
F
R
K
M
E
N
Q
D
A
L
--
V
C
I
S
E
-----
S
V
P
E
P
I
V
E
W
---
V
------
L
C
V
V
K
-----
K
E
E
K
V
L
H
E
L
F
G
T
----
D
-----
I
-----
R
C
C
A
R
N
E
L
G
R
E
--
C
T
R
L
F
T
I
D
--
L
N
Q
T
P
Q
T
----
T
L
P
Q
L
F
L
K
V
G
E
P
L
W
I
R
C
K
A
V
H
V
N
H
G
F
G
L
T
W
---------
E
L
E
N
K
A
L
E
-
E
G
N
Y
F
E
M
S
T
Y
S
T
N
-
R
T
M
I
R
-----
I
L
--------
F
A
F
V
---
S
S
V
A
R
NDTGYYT
C
S
S
S
K
H
P
S
QS
A
L
V
T
I
V
E
K
G
-
F
I
N
-------
A
T
E
D
Y
E
I
D
QY
E
E
F
C
F
S
VR
F
K
A
Y
P
Q
-
I
R
C
T
W
T
F
S
R
K
S
F
P
C
E
Q
K
-
G
L
D
N
G
Y
S
I
S
K
FCN
H
K
H
Q
P
G
E
Y
I
F
H
A
--
E
N
D
D
A
Q
F
T
K
M
F
T
L
N
29
Fugue
59.86
12%
14
* C9 *
4LTB
-
?
A:
[2-172]
-----------------------------
S
L
S
Q
A
S
A
D
L
E
A
T
L
R
H
K
L
T
V
M
Y
S
Q
I
N
G
--
A
S
R
A
----
L
D
D
V
------------
R
N
R
Q
Q
D
V
R
M
T
A
N
R
K
V
E
Q
L
Q
-------
Q
--
E
Y
T
E
M
-----
K
A
L
L
D
A
S
E
T
---
T
------
S
T
R
K
I
-----
K
E
E
E
K
R
V
N
S
K
F
D
----
T
-----
I
-----
Y
Q
I
L
L
K
K
K
S
E
I
--
Q
T
L
--
K
E
E
--
I
E
Q
S
L
T
K
----
R
----------------------
D
E
F
E
F
L
E
---------
K
A
S
K
L
R
G
I
-
S
T
K
P
V
Y
I
P
E
V
E
L
N
H
K
L
I
K
G
-----
I
H
--------
Q
S
T
I
---
D
L
K
-------------------
N
E
L
K
Q
C
I
G
R
-
L
Q
E
-------
L
T
P
---------------------------------------------------------------------------------
13
PsiBlast_PDB
57.35
25%
-53
- C8 -
2W3Y
1
?
A:
[114-188]
------------------------------------------------------------------------------------
Q
N
L
N
T
T
V
K
G
V
E
V
A
K
S
V
-------
I
--
Q
F
A
G
N
-----
V
I
A
G
N
V
T
G
F
---
A
------
T
F
L
Q
N
F
G
N
G
L
S
A
E
M
N
K
T
Q
A
N
Y
N
----
Y
L
Y
A
Y
S
T
-----
H
D
L
F
Q
D
T
S
G
N
V
--
F
Y
K
--
P
R
F
--
L
I
Y
G
T
H
F
----
K
Q
E
Q
K
K
I
A
T
S
C
A
S
Y
Q
E
V
N
L
E
F
G
V
D
T
V
G
G
T
F
---------
R
I
E
E
Y
F
S
N
-
E
T
F
K
K
K
V
D
N
F
L
D
K
Y
E
G
K
A
I
-----
D
D
--------
A
D
S
Y
---
F
D
D
-------------------
I
F
N
G
V
K
P
N
K
-
N
Y
V
-------
Y
-----------------------------------------------------------------------------------
14
PsiBlast_PDB
57.09
23%
-22
- C6 -
1X35
1
?
A:
[73-185]
---------------------------------------------------------------------G
I
T
V
L
T
H
S
E
LS
A
E
I
G
V
T
D
S
I
V
V
S
S
E
L
V
M
P
Y
T
-------
V
--
G
T
W
L
R
-----
G
V
A
A
N
W
S
K
Y
---
S
W
L
S
V
R
Y
T
Y
I
P
S
-----
C
P
S
S
T
A
G
S
I
H
M
G
----
F
-----
Q
---------
Y
D
M
--------
A
--
D
T
V
--
P
V
S
V
N
Q
L
----
S
N
L
R
G
Y
V
--
S
G
Q
V
W
S
G
S
A
G
L
C
F
I
N
G
T
R
C
S
D
---------
T
S
T
A
I
S
T
T
-
L
D
V
S
K
L
G
K
K
W
Y
P
Y
K
T
S
A
D
Y
-----
A
T
--------
A
V
G
V
---
D
V
N
-------------------
I
A
T
P
L
V
P
A
R
-
L
V
I
-------
A
L
L
D
G
S
S
S
------------
T
A
V
A
-
A
G
R
I
Y
C
T
Y
------
T
I
Q
-
M
I
E
P
T
A
S
A
L
N
----------
N
--------------------
8
PsiBlast_PDB
52.67
29%
-4
- C8 -
2NGR
-
B:
[129-165]
-----------------------------------------------------------------------------------------------
L
Y
P
H
V
-------
V
--
G
F
L
N
I
-----
D
E
S
Q
R
V
P
A
T
---
L
------
Q
V
L
Q
T
-----
L
P
E
E
N
Y
Q
V
L
R
F
L
----
T
-----
A
-----
F
L
V
Q
I
S
A
H
S
D
Q
--
N
K
M
--
T
N
T
--
N
L
A
V
V
F
G
----
P
N
L
L
W
A
K
D
A
A
I
T
L
K
A
I
N
P
I
N
T
F
T
K
F
L
L
D
H
Q
---------
G
E
L
F
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
52.58
29%
-1
- C8 -
1GRN
-
B:
[98-134]
-----------------------------------------------------------------------------------------------
L
Y
P
H
V
-------
V
--
G
F
L
N
I
-----
D
E
S
Q
R
V
P
A
T
---
L
------
Q
V
L
Q
T
-----
L
P
E
E
N
Y
Q
V
L
R
F
L
----
T
-----
A
-----
F
L
V
Q
I
S
A
H
S
D
Q
--
N
K
M
--
T
N
T
--
N
L
A
V
V
F
G
----
P
N
L
L
W
A
K
D
A
A
I
T
L
K
A
I
N
P
I
N
T
F
T
K
F
L
L
D
H
Q
---------
G
E
L
F
P
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
51.17
29%
-5
- C8 -
1AM4
-
RHG01_HUMAN
A:
[102-138]
-----------------------------------------------------------------------------------------------
L
Y
P
H
V
-------
V
--
G
F
L
N
I
-----
D
E
S
Q
R
V
P
A
T
---
L
------
Q
V
L
Q
T
-----
L
P
E
E
N
Y
Q
V
L
R
F
L
----
T
-----
A
-----
F
L
V
Q
I
S
A
H
S
D
Q
--
N
K
M
--
T
N
T
--
N
L
A
V
V
F
G
----
P
N
L
L
W
A
K
D
A
A
I
T
L
K
A
I
N
P
I
N
T
F
T
K
F
L
L
D
H
Q
---------
G
E
L
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
48.43
29%
-4
- C8 -
1TX4
-
A:
[101-137]
-----------------------------------------------------------------------------------------------
L
Y
P
H
V
-------
V
--
G
F
L
N
I
-----
D
E
S
Q
R
V
P
A
T
---
L
------
Q
V
L
Q
T
-----
L
P
E
E
N
Y
Q
V
L
R
F
L
----
T
-----
A
-----
F
L
V
Q
I
S
A
H
S
D
Q
--
N
K
M
--
T
N
T
--
N
L
A
V
V
F
G
----
P
N
L
L
W
A
K
D
A
A
I
T
L
K
A
I
N
P
I
N
T
F
T
K
F
L
L
D
H
Q
---------
G
E
L
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
47.95
29%
1
- C8 -
1RGP
-
A:
[137-173]
-----------------------------------------------------------------------------------------------
L
Y
P
H
V
-------
V
--
G
F
L
N
I
-----
D
E
S
Q
R
V
P
A
T
---
L
------
Q
V
L
Q
T
-----
L
P
E
E
N
Y
Q
V
L
R
F
L
----
T
-----
A
-----
F
L
V
Q
I
S
A
H
S
D
Q
--
N
K
M
--
T
N
T
--
N
L
A
V
V
F
G
----
P
N
L
L
W
I
N
P
I
N
T
F
T
K
F
L
L
D
H
Q
G
E
L
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
47.73
14%
53
- C9 -
2KZ9
-
VATE_YEAST
A:
[1-69]
-----------------------------------------------------------------------------------------------
M
A
S
A
I
-------
T
--
A
L
T
P
N
-----
Q
V
N
D
E
L
N
K
M
---
Q
------
A
F
I
R
K
-----
E
A
E
E
K
A
K
E
I
Q
L
K
----------
A
-----
D
Q
E
Y
E
I
E
K
T
N
I
--
V
R
N
--
E
T
N
--
N
I
D
G
N
F
K
----
S
K
L
K
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.92
32%
-12
- C8 -
2PTG
-
?
A:
[95-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
----
D
L
R
G
K
T
A
F
V
A
G
V
A
D
S
N
G
Y
G
W
A
I
C
K
L
L
R
A
A
G
---------
A
R
V
L
V
G
T
W
-
P
P
V
Y
S
I
F
K
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.16
29%
10
- C8 -
1OW3
-
A:
[137-173]
-----------------------------------------------------------------------------------------------
L
Y
P
H
V
-------
V
--
G
F
L
N
I
-----
D
E
S
Q
R
V
P
A
T
---
L
------
Q
V
L
Q
T
-----
L
P
E
E
N
Y
Q
V
L
R
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
45.10
35%
20
- C8 -
1JPU
1
GLDA_GEOSE
A:
[139-178]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
-----
E
-----
S
Y
R
F
Y
K
K
N
P
D
L
--
V
L
V
--
D
T
K
--
I
I
A
N
A
P
P
----
R
L
L
A
S
G
I
A
D
A
L
A
T
W
V
E
A
R
S
V
I
K
S
G
G
K
T
M
A
G
---------
G
I
P
T
I
A
A
E
-
A
I
A
E
K
C
E
Q
T
L
F
K
Y
G
K
L
A
Y
E
-----
S
V
--------
K
A
K
V
---
V
T
P
-------------------
A
L
E
A
V
V
E
A
N
-
T
L
L
-------
S
G
L
G
F
E
S
G
------------
G
L
A
A
-
A
H
A
I
H
N
G
F
------
T
A
L
-
E
G
E
I
H
H
L
T
H
G
----------
E
K
V
A
F
--
G
T
L
V
Q
L
A
L
E
E
H
---
4
PsiBlast_PDB
44.97
35%
19
- C8 -
1JQA
2
GLDA_GEOSE
A:
[139-178]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
-----
E
-----
S
Y
R
F
Y
K
K
N
P
D
L
--
V
L
V
--
D
T
K
--
I
I
A
N
A
P
P
----
R
L
L
A
S
G
I
A
D
A
L
A
T
W
V
E
A
R
S
V
I
K
S
G
G
K
T
M
A
G
---------
G
I
P
T
I
A
A
E
-
A
I
A
E
K
C
E
Q
T
L
F
K
Y
G
K
L
A
Y
E
-----
S
V
--------
K
A
K
V
---
V
T
P
-------------------
A
L
E
A
V
V
E
A
N
-
T
L
L
-------
S
G
L
G
F
E
S
G
------------
G
L
A
A
-
A
H
A
I
H
N
G
F
------
T
A
L
-
E
G
E
I
H
H
L
T
H
G
----------
E
K
V
A
F
--
G
T
L
V
Q
L
A
L
E
E
H
---
11
PsiBlast_PDB
44.87
30%
-30
* C7 *
4IXL
-
?
A:
[34-82]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
I
T
G
---------
N
E
--
I
G
T
H
-
D
G
Y
D
Y
E
F
W
K
D
E
G
G
Y
G
S
M
T
L
-----
N
S
--------
G
G
T
F
-----
S
-------------------
A
E
W
T
D
V
H
N
I
-
L
F
R
-------
K
G
Q
K
F
D
T
T
------------
Q
T
H
Q
-
Q
L
G
N
I
N
I
D
------
Y
G
V
-
N
Y
Q
P
N
G
S
S
Y
L
----------
A
V
Y
G
W
--
T
T
D
P
L
V
E
F
Y
I
V
---
5
PsiBlast_PDB
44.28
35%
14
- C8 -
1JQ5
2
GLDA_GEOSE
A:
[139-178]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
-----
E
-----
S
Y
R
F
Y
K
K
N
P
D
L
--
V
L
V
--
D
T
K
--
I
I
A
N
A
P
P
----
R
L
L
A
S
G
I
A
D
A
L
A
T
W
V
E
A
R
S
V
I
K
S
G
G
K
T
M
A
G
---------
G
I
P
T
I
A
A
E
-
A
I
A
E
K
C
E
Q
T
L
F
K
Y
G
K
L
A
Y
E
-----
S
V
--------
K
A
K
V
---
V
T
P
-------------------
A
L
E
A
V
V
E
A
N
-
T
L
L
-------
S
G
L
G
F
E
S
G
------------
G
L
A
A
-
A
H
A
I
H
N
G
F
------
T
A
L
-
E
G
E
I
H
H
L
T
H
G
----------
E
K
V
A
F
--
G
T
L
V
Q
L
A
L
E
E
H
---
15
PsiBlast_PDB
42.46
37%
30
- C8 -
3WBH
3
?
A:
[92-136]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
---
D
S
A
-------------------
C
S
A
T
Q
L
A
S
G
-
I
Y
S
-------
G
S
E
V
I
G
I
D
------------
A
E
G
N
P
V
E
T
V
L
E
L
A
------
Q
A
R
-
G
K
A
T
G
L
V
S
D
T
----------
R
L
T
H
A
--
T
P
A
A
F
A
A
H
Q
P
H
---